Figure 1. Number of Tuberculosis Cases: California, 1930-2011
1980
1982
1984
1986
1988
1990
1992
1994
1996
1998
2000
2002
2004
2006
2008
2010
0
1,000
2,000
3,000
4,000
5,000
6,000
California Department of Public Health, Tuberculosis Control Branch
Num
ber o
f Tu b
ercu
losi
s C
a ses
1930 1940 1950 1960 1970 19802,000
4,000
6,000
8,000
10,000
12,000
Year
Figure 2. Number of Tuberculosis Cases and Case Rates: California, 2002-2011
2002 2003 2004 2005 2006 2007 2008 2009 2010 20110
1,000
2,000
3,000
4,000
0
5
10
15
20
Year
*
Cas
e R
ate
per 1
00,0
00
Number of Cases
Case Rate per 100,000 Population
National Case RateCalifornia Department of Public Health, Tuberculosis Control Branch
*Num
ber o
f Cas
es
Figure 3. Tuberculosis Cases by Race/Ethnicity: California, 2011
Asian/Pacific Islander1,137 (48.9%)
Hispanic848 (36.5%)
Unknown1 (<0.1%)
Black 137 (5.9%)
American Indian/Alaska Native
5 (0.2%)
White197 (8.5%)
California Department of Public Health, Tuberculosis Control Branch
76
Figure 4. Tuberculosis Case Rates by Race/Ethnicity: California, 2002-2011
2002 2003 2004 2005 2006 2007 2008 2009 2010 20110
5
10
15
20
25
30
35
40Asian/Pacific IslanderBlackHispanicWhiteAmerican Indian/Alaska Na-tive
Year
Cas
es p
er 1
00,0
00
California Department of Public Health, Tuberculosis Control Branch
Figure 5. Tuberculosis Cases in Foreign-born and U.S.-born Persons: California, 2002-2011
2002 2003 2004 2005 2006 2007 2008 2009 2010 20110
500
1,000
1,500
2,000
2,500
3,000
0
20
40
60
80
100
U.S.-born Foreign-born Percent Foreign-born
Num
ber o
f Cas
es
Per c
ent
of C
ase s
California Department of Public Health, Tuberculosis Control Branch
78
Figure 6. Tuberculosis Cases by Country of Origin: California, 2011
U.S.-born511 (21.9%)
Foreign-born1,787 (76.9%)
Unknown27 (1.2%)
Philippines375 (21.0%)
Mexico497 (27.8%)All Other
Countries675 (37.8%)
Vietnam240 (13.4%)
California Department of Public Health, Tuberculosis Control Branch
Figure 7. Tuberculosis Cases in Persons 0-4 Years of Age: California, 2002-2011
1 2 3 4 5 6 7 8 9 100
20
40
60
80
100
120
140
0
0.5
1
1.5
2
2.5
3
3.5
4
4.5
Num
ber o
f Cas
es
Perc
ent o
f Cas
es
Number of Cases Percent of Cases
California Department of Public Health, Tuberculosis Control Branch
Year
2002 2003 2004 2005 2006 2007 2008 2009 2010 2011
Figure 8. Tuberculosis Cases by Verification Criteria: California, 2011
Provider Diagnosis98 (4.2%)
Positive Culture1,840 (79.1%)
Clinical Case336 (14.5%)
Positive Smear12 (0.5%)
California Department of Public Health, Tuberculosis Control Branch
81
NAAT*39 (1.7%)
*NAAT= Nucleic Acid Amplification Test
Figure 9. Deaths in Persons with Tuberculosis: California, 2000-2009
2000 2001 2002 2003 2004 2005 2006 2007 2008 20090
100
200
300
400
0
2
4
6
8
10
12
Year
Perc
ent o
f Cas
es
Num
ber o
f Dea
ths
California Department of Public Health, Tuberculosis Control Branch
Dead at Diagnosis
Died During Treatment Died Before Starting Treatment
Percent Dying with Tuberculosis
Figure 10. Tuberculosis Cases by HIV/AIDS Diagnosis:* California, 2001-2010
2001 2002 2003 2004 2005 2006 2007 2008 2009 20100
50
100
150
200
250
300
0
2
4
6
8
Year
Num
ber o
f Cas
es w
ith H
IV/A
IDS
Per c
ent o
f Ca s
es w
it h H
IV/A
I DS
* Match found in HIV/AIDS Registry, California Department of Public Health, Office of AIDS
Number of Tuberculosis Cases with HIV/AIDSPercent of Tuberculosis Cases with HIV/AIDS
83
California Department of Public Health, Tuberculosis Control Branch
Figure 11. HIV/AIDS-associated Tuberculosis* by Race/Ethnicity: California, 2001-2010
2001 2002 2003 2004 2005 2006 2007 2008 2009 20100
25
50
75
100
125
150
HispanicBlackWhiteAsian/Pacific IslanderAmerican Indian/Alaska Na-tive
Year
Num
ber o
f Cas
es w
ith H
IV/A
IDS
* Match found in HIV/AIDS Registry, California Department of Public Health, Office of AIDS
California Department of Public Health, Tuberculosis Control Branch
1 2 3 4 5 6 7 8 9 1005
101520253035404550
Figure 12. Tuberculosis Cases with Multidrug Resistance (MDR) on Initial or Final Drug
Susceptibility Testing:* California, 2000-2009N
umbe
r of M
DR
Tu
berc
ulos
is C
ases
*Cases with resistance to at least isoniazid, and either rifampin, rifabutin or rifapentine reported on the Initial Drug Susceptibility Report (Follow-up 1) or on the Case Completion Report (Follow-up 2)
35
43
34
41
36 37
2832 33
38
2001 20092000 2002 2003 2004 2005 2006 2007 2008
California Department of Public Health, Tuberculosis Control Branch
Initial Susceptibility Test Final Susceptibility Test
Figure 13. Tuberculosis Cases with Initial Multidrug Resistance (MDR):* California, 2007-2011
*Cases with initial drug resistance to at least isoniazid, and either rifampin, rifabutin or rifapentineCalifornia Department of Public Health, Tuberculosis Control Branch
Long BeachPasadena
BerkeleySan Francisco
³25 cases
15-24 cases
5-14 cases
1-4 cases
None
Initial MDR Cases:2007-2011
Figure 14. Tuberculosis Cases1 by Outcome of Therapy: California, 2009
Completed Therapy £12 Months1,780 (74.5%)
Completed Therapy >12 Months235 (9.8%)
Moved2
97 (4.1%)
Died180 (7.5%)
Lost3
21 (0.9%) Refused17 (0.7%)
Other31 (1.3%)
1 Patient was alive at diagnosis and started on an initial drug regimen of two or more drugs.2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed;
final outcome not available.3 Patient could not be located prior to the completion of treatment.
NoInformation28 (1.2%)
California Department of Public Health, Tuberculosis Control Branch
Figure 15. Outcome in Tuberculosis Cases for Whom One Year or Less of Treatment was Indicated1:
California, 2009
Completed Therapy £12 Months1,770 (76.2%)
Completed Therapy >12 Months195 (8.4%)
Moved2
91 (3.9%)
Died175 (7.5%)
Lost3
21 (0.9%)
Refused16 (0.7%)
Other29 (1.2%)
NoInformation 25 (1.1%)
1 Excludes cases with rifampin resistant disease, cases with meningeal disease, and cases less than 15 years of age with disseminated tuberculosis disease.2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed; final outcome not available.3 Patient could not be located prior to the completion of treatment.
California Department of Public Health, Tuberculosis Control Branch
Figure 16. Outcome in Tuberculosis Cases for Whom Greater than One Year of Treatment
was Indicated:1 California, 2009
Completed Therapy £12 Months10 (14.9%)
Completed Therapy >12 Months40 (60.0%)
Moved2
6 (9.0%)
Died5 (7.5%)
NoInformation 3 (4.5%)
1 Includes cases with rifampin resistant disease, cases with meningeal disease, and cases less than 15 years of age with disseminated tuberculosis disease.
2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed; final outcome not available.
California Department of Public Health, Tuberculosis Control Branch
Refused1 (2.0%)
Other2 (3.0%)
Figure 17. Completion of Tuberculosis Therapy: California, 2000-2009
2000 2001 2002 2003 2004 2005 2006 2007 2008 20090
20
40
60
80
100
Perc
ent o
f Cas
es C
ompl
etin
g T
hera
py
CompletedCompleted in 1 year or less
Note: Excludes cases with rifampin resistant disease, cases with meningeal disease, cases less than 15 years of age with disseminated tuberculosis disease, and those that died during treatment.
90
California Department of Public Health, Tuberculosis Control Branch