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EC – JPIAMR Strategic Interactions
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EC-JPIAMR Strategic Interactions
• AMR strategy – not JPI strategy
• Antimicrobial resistance is a global societal challenge that must be met by strategies for both research and policy development
• AMR must be seen in a One Health perspective and thus requires strategies for research and policy development in drug development, human clinical medicine, animal health and the environment
• International - EU - National
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2010 JPIAMR proposed by Sweden and Italy
2011 EC Action plan against the rising threats from Antimicrobial Resistance
2012 EC CSA JPIAMR
2013 JPIAMR Strategic Research Agenda
2014 IMI2 Strategic Research Agenda
2012 IMI1 Call #6 on AMR
2015 EC ERA-Net Cofund JPI-EC-AMR
2017 EC CSA EXEDRA
2016 Joint AMR workshop by JPIAMR, EC, IMI, and NIH
2013 IMI1 Call #11 on AMR
2012 IMI1 Call 8 on AMR
2013 IMI1 Call #9 on AMR
2015 WHO Global Action Plan on AMR
2018 JPIAMR Strategic Research & Innovation Agenda
2017 EC A European One Health Action Plan against Antimicrobial Resistance (AMR)
2014 JPIAMR Call 1
2015 JPIAMR Call 2
2016 JPIAMR Call 3/4
2017 JPIAMR Call 5
2018 JPIAMR Call 6/7/8
2016 UN General Assembly on AMR
2017 EC Joint Action EU-JAMRAI
2017 G20 & G7 Priority
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JPIAMR 26 Members Countries
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•
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JPIAMR Governance Structure
STEERING COMMITTEE
WG2 Govern
ance
SCIENTIFIC ADVISORY BOARD
WG3 Globalis
ation
WG5/6 Research
Alignment
WG4 Policy
Ailgnment
SECRETARIAT
MANAGEMENT BOARD
NATIONAL EXPERT PANELS
Core Call Steering Group
WG7 Industry relation
s
WG1 Evaluati
on
Call X Steering Group
NATIONAL POLICY GROUPS
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EC Action plan against the rising threats from Antimicrobial Resistance 2011
Action no 11 Reinforce and co-ordinate research efforts, in particular: … - Support the launch of a Joint Programming
Initiative aimed at coordinating national research activities related to AMR
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EC CSA JPIAMR 2012-2015
Objectives: • Organisation – Communication Platform • Mapping of research activities • Strategic Research Agenda • Implementation Plan • Industry Engagement • Evaluation Framework
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JPIAMR
Strategic Research Agenda
6 Research Pillars
• Therapeutics - new drugs, vaccines, alternatives, and
incentives to bring drugs to market.
• Diagnostics - new, better, faster
• Surveillance - new standards and methods for
surveillance of drug resistance in humans, animals, and
the environment
• Transmission - emergence and selection mechanisms for
drug resistance
• Environment - role of the environment for the spread of
drug resistance
• Intervention -evidence base for prevention and infection
control measures
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EC ERA-Net Cofund JPI-EC-AMR 2015-2020
Objectives: • Cofunded OneHealth call on Transmission
of AMR between humans, animals, and the environment
• Additional calls • Industry Engagement
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EC CSA EXEDRA 2017-2020
Objectives: • Sustainability • Policy alignment • Research alignment
• Strategic Research and Innovation Agenda
• Virtual Research Institute • Mapping research activities and
construction of database
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Therapeutics 29%
Diagnostics 0%
Surveillance 4%
Transmission 49%
Environment 9%
Interventions 9%
RESEARCH PROJECTS
Therapeutics 27%
Diagnostics 14%
Surveillance 27%
Transmission 14%
Environment 9%
Interventions 9%
NETWORKS/WORKING GROUPS
€
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A global AMR scientific platform
for scientific interaction and
research capacity to:
Jointly address big research
questions/projects
Facilitate research and training on
AMR
(knowledge, expertise and
funding)
Stimulate networks from
currently independent
research communities in a
One Health approach
Improve the way resources are
shared and used between AMR stakeholders
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EC A European One Health Action Plan against Antimicrobial Resistance (AMR)
2017
3. BOOSTING RESEARCH, DEVELOPMENT AND INNOVATION ON AMR …The proposed AMR research strategy covers the full One Health spectrum, addressing human and animal health as well as the role of the environment. It takes into account the priorities set out in the WHO Global Action Plan on AMR, the JPIAMR and national action plans. …
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G7 Health Minister Meeting Milan Nov. 5-6
AMR in focus at G 7 Health Ministers meeting in Milan
…Health Ministers expressed that they welcome the establishment of the Global AMR R&D Hub and call to ensure it becomes an effective platform to align and increase global investment in much needed R&D based on WHO recommendations, e.g. the Priority Pathogen List (PPL). They expressed support for the collaboration of the Global AMR R&D Hub with existing international networks and initiatives like the Interagency Coordination Group on AMR, the Global Antibiotic Research & Development Partnership (GARDP), CARB-X and the Joint Programming Initiative on AMR (JPIAMR). https://www.jpiamr.eu/amr-in-focus-at-g-7-health-ministers-meeting-in-milan/
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ANTIBIOTIC R&D FUNDING INTERNATIONAL INITIATIVES
Phase I
Phase II
Phase III
Basic Science Pre-clinical Mark
et
National Science Research Agencies
EC FP / European Research Council
ND4BB
US NIH / NIAID
EIB’s InnovFin
UK / China Global Innovation Fund
Recently Launched Existed Prior 2016
17
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2010 JPIAMR proposed by Sweden and Italy
2011 EC Action plan against the rising threats from Antimicrobial Resistance
2012 EC CSA JPIAMR
2013 JPIAMR Strategic Research Agenda
2014 IMI2 Strategic Research Agenda
2012 IMI1 Call #6 on AMR
2015 EC ERA-Net Cofund JPI-EC-AMR
2017 EC CSA EXEDRA
2016 Joint AMR workshop by JPIAMR, EC, IMI, and NIH
2013 IMI1 Call #11 on AMR
2012 IMI1 Call 8 on AMR
2013 IMI1 Call #9 on AMR
2015 WHO Global Action Plan on AMR
2018 JPIAMR Strategic Research & Innovation Agenda
2017 EC A European One Health Action Plan against Antimicrobial Resistance (AMR)
2014 JPIAMR Call 1
2015 JPIAMR Call 2
2016 JPIAMR Call 3/4
2017 JPIAMR Call 5
2018 JPIAMR Call 6/7/8
2016 UN General Assembly on AMR
2017 EC Joint Action EU-JAMRAI
2017 G20 & G7 Priority
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Key Success Factors for Strategic Interaction between EC and JPIAMR
• Coherent global political landscape
• Policy alignment on national level
• Policy alignment JPIAMR – EC
• True Partnership with frequent information exchange and strategic cooperation
• JPIAMR tool for international research collaboration and achieving goals of EC Global action plan.
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