Department of Pharmacology and Biochemistry
Courses Specifications
2017-2018
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Contents
Medical and Pharmacy Terminology ..................................................................................... 2
Anatomy and Histology ........................................................................................................... 6
Physiology ............................................................................................................................... 12
Pharmacology-1 ...................................................................................................................... 16
Pharmacology-2 ...................................................................................................................... 22
Toxicology ............................................................................................................................... 28
Biostatistics ............................................................................................................................. 32
OTC abuse .............................................................................................................................. 36
General Biology ...................................................................................................................... 40
Biochemistry-1 ........................................................................................................................ 44
Biochemistry-2 ........................................................................................................................ 50
Clinical Biochemistry ............................................................................................................. 56
Pharmacogenomics ................................................................................................................. 62
Clinical toxicology .................................................................................................................. 65
Veterinary pharmacy ............................................................................................................. 68
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Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Medical and Pharmacy Terminology
Course Code: PB 102
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology & Biochemistry
Academic year/ level: Spring Semester 2017/2018 Level 1
Prerequisite: None
Credit hours: Lecture: 1 Practical: 0 Total: 1
2. Course Aims:
Learn and recognize common medical and pharmaceutical terms and gain basic understanding
of healthcare language. Acquire the knowledge needed for reading health reports in order to
communicate well with other health-care providers.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A1 a1. Identify basic terms in pharmacy that are relevant to orienting students to
pharmacy.
A22
a2. Recognize the proper pharmaceutical and medical terminology,
abbreviations, and symbols related to the central nervous system CNS).
a3.
Define and use prefixes, suffixes, and combining forms that facilitate the
ability to translate medical terms regarding cardiovascular system (CVS) and
gastrointestinal tract (GIT).
a4. Illustrate different forms of writing that help to produce a readable piece of
scientific essay with minimal, or no, language mistakes.
a5. Explain how medical terminology is relevant to communicate with other
health care providers.
b. Intellectual Skills:
At the end of this course, student should be able to:
B21
b1 Predict the meaning of different medical terms regarding CNS
b2 Differentiate between different medical terms and abbreviations related to
CVS
b3 Classify parts of medical term relevant to GIT
b4
Generate well organized translations of selected medical English extracts
from the reading and comprehension passages into Arabic with special focus
on terminology.
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c. Professional and Practical Skills:
At the end of this course, student should be able to:
C1
c1. Apply gained knowledge to analyze parts of medical terms in other basic and
clinical sciences.
c2. Create and analyze authentic materials and discuss issues presented in the
scientific literature.
c3. Utilize acquired information for interpretation of terms and abbreviations in
pharmacy.
c4. Manipulate and interact correctly with other healthcare providers.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D1 d1. Communicate effectively in a scientific language.
D5 d2. Use information technology tools to retrieve information and use on-line
data base related to medical and pharmaceutical abbreviations.
4. Contents:
4.1.Lectures:
4.2. Practical: Not applicable
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Group discussions
5.3. Assignments and self-learning
Study
week Topics
No. of
Credit Hours
1. Introduction (basic word parts, combining vowel rules ,word
building and interpreting medical terms 1
2. Basic word structure (Prefixes) 1
3. Basic word structure (Suffixes) 1
4. Roots of CNS + (Quiz 1) 1
5. Terminology of CNS 1
6. Roots of CVS 1
7. Terminology of CVS 1
8. (Quiz 2)
9. Roots of GIT 1
10. Terminology of GIT 1
11. Medical abbreviations. 1
12. Medical Reports 1
13. Exercise 1
14. Final Exam
Total:
1 credit hour 15.
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6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
3. Quizzes To assess knowledge, understanding and intellectual skills.
6.2. Assessment schedule:
Assessment 1 Quiz 1 4thweek
Assessment 2 Quiz 2 8thweek
Assessment 3 Assignment all over the term
Assessment 4 Written exam 14th&15thweeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Activity (assignments) 5
2. Final-Term Exam 75
Total 100%
7. List of References:
No. References Type
1. Medical Terminology for Health Care Professionals by Jane Rice.
(Pearson; 8thedition, 2014) Textbook
2. USA Journal of pharmacy Education, Electronic Journal Periodical
3. https://www.online-medical-dictionary.org/ Website
8. Matrix of course contents versus ILOs:
a. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1.
Introduction (basic word parts,
combining vowel rules ,word building
and interpreting medical terms
a1 b4 c1 --
2. Basic word structure (Prefixes) a1 b4 c1 --
3. Basic word structure (Suffixes) a1 b4 c1 --
4. Roots of CNS a2 b1, b4 c1,c2 --
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5. Terminology of CNS a2 b1, b4 c1,c2 --
6. Roots of CVS a3 b2, b4 c1,c2 --
7. Terminology of CVS a3 b2, b4 c1,c2 --
9. Roots of GIT a3 b3, b4 c1,c2 --
10. Terminology of GIT a3 b3, b4 c1,c2 --
11. Medical abbreviations. a4, a5 b4 c3,c4 d1, d2
12. Medical Reports a4, a5 b4 c4 d1, d2
13. Exercise a4, a5 b4 c4 d1, d2
Name Signature
Course Coordinator: Dr. Eman Mahmoud
Head of Department: Prof. Dr. Hassn Elkashef
Approval Date 6/2/2018
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Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Anatomy and Histology
Course Code: PB 203
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology and Biochemistry
Academic year/ level: Fall Semester 2017/2018 Level 2
Prerequisite: General biology (PB 101)
Credit hours: Lecture: 2 Practical: 1 Total: 3
2. Course Aims:
To provide knowledge and understanding of the basic anatomical structure of different body
systems such as digestive, respiratory, cardiovascular, urinary and nervous systems and the
correlation between their functions and anatomical structure. To introduce theoretical and
practical knowledge of the normal structure of different cells and tissues of the human body
by means of light and electron microscope as well as different histological tools and
techniques for preparation of histological sections.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A1
a1 Explain the basic anatomical structure of the different systems of the body
and its correlation to function.
a2. Define and describe the histological characteristics of normal cells,
cytoplasmic components, membranous and non-membranous cell organelles.
a3. Mention the characteristics of the four basic tissues of human body.
a4. Describe and compare between different blood elements and their
development.
b. Intellectual Skills:
At the end of this course, student should be able to:
B2 b1. Develop good laboratory practice in histological practical work
B18
b2. Compare the different anatomical structure of organs in the human body
b3. Select appropriate methods to reveal specific microscopic features of cells
and tissues
b4. Discriminate slides of different organs or tissues obtained from different
sources.
b5. Interpret basic results in a complete blood count report
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c. Professional and Practical Skills:
At the end of this course, student should be able to:
C1 c1. Utilize the proper histological and anatomical terminology to report and
describe histopathological differences in tissue sections
C5
c2. Differentiate between different cell organelles
c3. Assess the differences between different types of epithelium, connective
tissue cells and bone cells
c4. Use the microscope to distinguish different blood cells in blood films
c5. Identify different types of tissues and organs and to differentiate between
surface markings
d. General and Transferable Skills:
At the end of this course, student should be able to:
D1 d1. Enhance the communication skills through communication with colleagues
during preparing, essays and assignments.
D3 d2. Express themselves freely and work effectively within a team frame.
D6 d3. Develop the skills required for continued self-learning
4. Contents:
4.1.Lectures:
Study
week Topics
No. of
Credit Hours
1. Cytology: structure of cytoplasmic organelles and the nucleus 2
2. Epithelial tissue: simple, stratified, neuron and glandular
epithelium 2
3. Connective tissue fibers, cells and types 2
4. Cartilage: structure and different types of cartilage + (quiz 1) 2
5.
Bone: cell types and ossification-anatomy
Bone: cell types and ossification-histology
2
6.
Cardiovascular system and respiratory system-anatomy
Muscular tissue: skeletal muscles, smooth muscles and
cardiac muscles-histology
2
7. Nervous tissue: neuron, neuroglial cells and autonomic
ganglia 2
8. Quiz 2
9. Blood elements, arteries and veins. 2
10.
Lymphatic system: spleen, thymus and lymph nodes-anatomy
Lymphatic system: spleen, thymus and lymph nodes-
histology
2
11.
Digestive system especially liver and pancreas-anatomy
Digestive system especially liver and pancreas-histology
2
12. Urinary and genital systems –anatomy + revision 2
13. Urinary and genital systems-histology + revision 2
14. Final Exam
Total:
2 credit hours 15.
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4.2. Practical:
Study
week Topics
No. of
Credit Hours
1. Epithelial tissue: simple, stratified, neuronal and glandular
epithelium 1
2. Epithelial tissue: simple, stratified, neuronal and glandular
epithelium (revision) 1
3. Connective tissue fibers, cells and types 1
4. Connective tissue fibers, cells and types (revision) 1
5. Cartilage: structure and different types of cartilage 1
6. Cartilage: structure and different types of cartilage (revision) 1
7. Bone: cell types and ossification. 1
8. Quiz 2
9. Bone: cell types and ossification. (revision) 1
10. Muscular tissue: skeletal muscles, smooth muscles and cardiac
muscles. 1
11. Muscular tissue: skeletal muscles, smooth muscles and cardiac
muscles. (revision) 1
12. Revision 1
13. Practical Exam 1
14. Final Exam
Total:
1 credit hour 15.
5. Teaching and Learning methods:
5.1. Lectures
5.2. Practical classes
5.3. L.M.S
5.4. Group discussion
5.5. Assignment, activity (homework)
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam To assess professional and practical skills.
3. Course work To assess knowledge, understanding, intellectual skills, general &
transferable skills.
4. Quizzes To assess knowledge, understanding and intellectual skills.
6.2.Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
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Assessment 3 Assignment/activity
(histology drawing notebook) all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Written exam 14th & 15th weeks
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity
(histology drawing notebook) 5
2. Final-Term Exam 50
3. Practical Exam 25
Total 100%
7. List of References:
No. Reference Type
1.
-Junqueira's basic histology: Text and Atlas, by Anthony Mescher
(McGraw-Hill Education/Medical; 13th edition, 2013)
-Ross and Wilson Anatomy and Physiology in Health and Illness by
Anne Waugh and Allison Grant (Churchill Livingstone; 12th edition,
2014)
Textbook
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Cytology: structure of cytoplasmic
organelles and the nucleus a2 b3 c1, c2 --
2. Epithelial tissue: simple, stratified,
neuron and glandular epithelium a3
b1 , b3,
b4 c1, c3 --
3. Connective tissue fibers, cells and types a3, a4 b2 , b3,
b4 c1, c3 --
4. Cartilage: structure and different types
of cartilage a3, a4
b2 , b3,
b4 c1, c3 d1, d3
5.
Bone: cell types and ossification-
anatomy
Bone: cell types and ossification-
histology
a1, a2,
a3 b2, b4
c1, c3,
c5 d1, d3
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6.
Cardiovascular system and respiratory
system-anatomy
Muscular tissue: skeletal muscles,
smooth muscles and cardiac muscles-
histology
a1, a2,
a3 b2, b4
c1, c3,
c5 d1, d3
7. Nervous tissue: neuron, neuroglial cells
and autonomic ganglia a3, a4 b2, b4 c1, c3 d1, d3
9. Blood elements, arteries and veins. a2, a4 b2, b4,
b5 c1, c4 d1, d3
10.
Lymphatic system: spleen, thymus and
lymph nodes-anatomy
Lymphatic system: spleen, thymus and
lymph nodes-histology
a1, a2,
a3, a4
b2, b4,
b5
c1, c4,
c5 d1, d3
11.
Digestive system especially liver and
pancreas-anatomy
Digestive system especially liver and
pancreas-histology
a1, a3,
a4 b2, b4 c1, c5 d1, d3
12. Urinary and genital systems –anatomy a1, a3,
a4 b2, b4 c1, c5 d1, d3
13. Urinary and genital systems-histology
8.2. Practical:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Epithelial tissue: simple, stratified,
neuronal and glandular epithelium a2, a3
b1, b3,
b4 c1, c3 d1, d2
2.
Epithelial tissue: simple, stratified,
neuronal and glandular epithelium
(revision)
a2, a3 b1, b3,
b4 c1, c3 d1, d2
3. Connective tissue fibers, cells and types a2, a3 b1, b3,
b4 c1, c3 d1, d2
4. Connective tissue fibers, cells and types
(revision) a2, a3
b1, b3,
b4 c1, c3 d1, d2
5. Cartilage: structure and different types
of cartilage a2, a3
b1, b3,
b4 c1, c3
d1, d2,
d3
6. Cartilage: structure and different types
of cartilage (revision) a2, a3
b1, b3,
b4 c1, c3
d1, d2,
d3
7. Bone: cell types and ossification. a2, a3 b2, b3,
b4 c1, c3
d1, d2,
d3
9. Bone: cell types and ossification.
(revision) a2, a3 b2, b3,
b4 c1, c3
d1, d2,
d3
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10. Muscular tissue: skeletal muscles,
smooth muscles and cardiac muscles.
a1, a3,
a4
b2, b3,
b4 c1, c3
d1, d2,
d3
11.
Muscular tissue: skeletal muscles,
smooth muscles and cardiac muscles.
(revision)
a1, a3,
a4
b1, b2,
b3 c1, c3
d1, d2,
d3
12. Revision
Name Signature
Course Coordinator: Prof. Dr. Sanaa Elsherbiny
Head of Department: Prof. Dr. Hassan Elkashef
Approval Date 10/9/2017
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Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Physiology
Course Code: PB 204
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology & Biochemistry
Academic year/ level: Fall Semester 2017/2018 Level: 2
Prerequisite: General biology (PB 101)
Credit hours: Lecture: 2 Practical: 0 Total: 2
2. Course Aims:
This course aims to introduce the basic principles of physiology and human body
homeostasis. To provide knowledge and understanding of the normal structure and
functions of the major body systems. Moreover, the course integrates physiological data
and mechanisms with clinical applications.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, students should be able to:
A1 a1. List the functional organization and structure of various body systems and its
relation to function.
A11
a2. Describe the structure and functions of the autonomic nervous system, its
higher centers, autonomic receptors and chemical transmitters
a3. Explain the integration between cardiovascular and renal systems to maintain
homeostasis.
a4. Recall the basic functions of endocrine hormones and their effects on
different body systems.
a5.
Describe the functional structure of the respiratory system, the mechanism of
respiratory cycle and some conditions related to disorders of the respiratory
system.
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b. Intellectual Skills:
At the end of this course, students should be able to:
B18
b1. Integrate the physiological performances of different body system with
overall body homeostasis.
b2.
Assess the general classification of the autonomic nervous system and
compare the function and distribution of sympathetic and parasympathetic
divisions.
b3. Predict the events of the cardiac cycle and the physiological consequences of
factors affecting cardiac output, heart rate and blood pressure.
b4. Classify hormones secreted by endocrine glands and the different functions
of them in the body.
b5. Analyze the physiological roles of gastrointestinal, renal and respiratory
systems in maintaining normal homeostasis.
c. Professional and Practical Skills:
At the end of this course, students should be able to:
C5
c1. Apply physiological information to other basic and clinical sciences.
c2. Employ basic physiological measurements to test different body functions.
c3. Manage and diagnose common endocrinal conditions based on data from
clinical lab tests
c4. Apply clinical skills and tools in assessment of body functions in health.
d. General and Transferable Skills:
At the end of this course, students should be able to:
D2 d1. Retrieve physiological information resources.
D3 d2. Work in a team to participate effectively as member of the health care team
D6 d3. Develop the skills required for continued self-learning.
4. Contents:
4.1. Lectures:
Study
week Topics
No. of
Credit Hours
1
Electrophysiological properties & cell membrane
Physiology of autonomic nervous system (parasympathetic
NS)
2
2 Physiology of autonomic nervous system (sympathetic NS) 2
3. Physiology of cardiovascular system (cardiac functions,
properties and cardiac cycle) 2
4. Physiology of cardiovascular system (blood vessels and
blood pressure regulation) + (quiz 1) 2
5 Physiology of endocrine system (adrenal gland) 2
6 Physiology of endocrine system (thyroid and parathyroid
gland) 2
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5. Teaching and Learning Methods:
5.1. Lectures
5.2. L.M.S
5.3. Group assignment
5.4. Discussions of clinical cases
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Course work To assess knowledge, understanding, intellectual skills, general &
transferable skills.
3.Quizzes To assess knowledge, understanding and intellectual skills.
6.2.Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment (essay) all over the term
Assessment 4 Written exam 14th &15th weeks
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment (essay) 5
2. Final-Term Exam 75
Total 100%
7 Physiology of endocrine system (anterior and posterior
pituitary gland) 2
8. Quiz 2
9. Physiology of endocrine system (pancreas) 2
10 Physiology of upper gastrointestinal tract 2
11 Physiology of lower gastrointestinal tract 2
12 Physiology of renal system 2
13 Physiology of respiratory tract 2
14. Final Exam
Total:
2 credit hours 15.
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7. List of References:
No. Reference type
1.
1.1. Ross and Wilson Anatomy and Physiology in Health
and Illness by Anne Waugh and Allison Grant (Churchill
Livingstone; 12th edition, 2014)
1.2. Hole's Essentials of Anatomy and Physiology by David
Shier, Jackie Butler andRicki Lewis (McGraw-Hill
Education; 12th edition, 2014)
1.3. Ganong's Review of Medical Physiology by Kim E.
Barrett, Susan M. Barman, Scott Boitano and Heddwen L.
Brooks(McGraw-Hill Education; 25th edition, 2015).
textbook
2. https://www.physiology.org & The Journal of Physiology website
8. Matrix of course contents versus ILOs:
8.1.Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1-2 Physiology of autonomic nervous
system a1, a2 b1, b2 c1,c2 --
3-4 Physiology of cardiovascular
system a1, a3 b1,b3 c1,c2,c4 d1
5-7 Physiology of endocrine system a1,a4 b1,b4 c3 d1
9. Physiology of endocrine system a1,a4 b1,b4 c3 d1,d2
10-11 Physiology of gastrointestinal
tract a1 b1, b5 c1,c4 d2,d3
12 Physiology of renal system a1, a3 b1, b5 c1,c4 d2,d3
13 Physiology of respiratory system a1,a5 b1, b5 c1,c4 d2,d3
Name Signature
Course Coordinator: Dr. Ahmed Saad
Head of Department: Prof. Dr. Hassan A. Elkashef
Approval Date 10/9/2017
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Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Pharmacology-1
Course Code: PB 331
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology and Biochemistry
Academic year/ level: Fall Semester 2017/2018 Level three
Prerequisite: Physiology (PB 204)
Credit hours: Lecture: 3 Practical: 1 Total: 4
2. Course Aims:
To provide knowledge and understanding of the basic principles of pharmacokinetics and
pharmacodynamics and introduce concepts of drug action with illustration of different
mechanisms to provide comprehensive coverage of the major drug groups affecting different body
systems; autonomic nervous system, cardiovascular system, respiratory system, and autacoids.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, students should be able to:
A8
a1.
Identify the basic principles of pharmacodynamics, including modes of drug action and
terms related to drug-receptor interaction (efficacy and potency, agonists and
antagonists).
a2 Recognize the fundamental concepts of pharmacokinetics, including absorption,
distribution, metabolism and elimination.
A13
a3. Outline significant indications, adverse effects and interactions of different classes of
autonomic drugs (agonists and antagonists of adrenergic and cholinergic receptors).
a4 Recall basic pharmacological aspects of autacoids, autacoid antagonists and drugs
acting on the respiratory system.
a5
Recognize significant indications, adverse effects and interactions of drugs used in
treatment of cardiovascular diseases (hypertension, angina, heart failure and
arrhythmia).
b. Intellectual Skills:
At the end of this course, students should be able to:
B9
b1. Predict the pharmacodynamics of different classes of drugs affecting autonomic
nervous system and proper selection in various disease conditions.
b2 Compare the pharmacokinetics and pharmacodynamics of different drugs affecting
respiratory system and proper specification of dosage and dose regimen.
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B11
b3
Differentiate between first, second and third line drugs used in treatment of
hypertension in patients with or without other comorbidities (asthma, diabetes,
chronic kidney disease, …)
b4 Create a therapeutic plan for management of different types of ischemic heart
diseases (angina and myocardial infarction).
b5 Classify types of heart failure and identify the therapeutic modality of each type.
c. Professional and Practical Skills:
At the end of this course, students should be able to:
C11
c1 Design an experimental protocol to show the effects of the drugs on
laboratory animals, including mice and rats.
c2 Apply different routes of drug administration and assess the precise skills
regarding calculation of drug doses.
c3 Handle experimental animals as well as different isolated tissue preparations.
C13 c4 Utilize the problem-based learning (PBL) to identify the interactions and
adverse effects of different agonists and antagonists of autonomic receptors.
d. General and Transferable Skills:
At the end of this course, students should be able to:
D2 d1 Retrieve drug information resources.
D3 d2 Work effectively within a team.
D11 d3 Reach appropriate solutions in a case based modules.
4. Contents:
4.1.Lectures:
Study
week Topics
No. of
Credit Hours
1. -Pharmacodynamics
Receptors, efficacy, potency, agonist and antagonists 3
2. -Pharmacokinetics
Absorption, distribution, metabolism & elimination of drugs
3
3. - Introduction to autonomic pharmacology 3
4. - Acetylcholine receptors agonists and antagonists
- Neuromuscular blockers + (Quiz 1)
3
5. - Adrenoceptors activating drugs 3
6. - Adrenoceptors blocking drugs 3
7. Autacoid and autacoid antagonists 3
8. Quiz 2
9. Drugs acting on respiratory system 3
10. Anti-hypertensive drugs 3
11. Anti-anginal drugs 3
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4.2. Practical:
Study
week Topics
No. of
Credit Hours
1. Handling of animals
1
2. Routes of drug administration
1
3. Dose calculation
1
4. Mice handling and injection
1
5. Hypnotics
1
6. PBL
1
7. Revision
1
8. Quiz 2
9. In-vitro experiments
1
10. Effect of acetylcholine on isolated rabbit intestine
1
11. Effect of barium chloride on isolated rabbit intestine
1
12. Effect of acetylcholine and Bacl2 in presence of atropine on
isolated rabbit intestine 1
13. Practical Exam 1
14. Final Exam
Total:
1 credit hour 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Practical session using laboratory equipment and experimental animals
5.3. Group assignment
5.4. Case discussions and PBL
5.5. L.M.S
12. Drugs for treatment of congestive heart failure 3
13. Anti-arrhythmic drugs 3
14. Final Exam
Total:
3 credit hours 15.
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6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam To assess professional and practical skills.
3. Course work To assess knowledge, understanding, intellectual skills, general &
transferable skills.
4. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes To assess knowledge, understanding and intellectual skills.
6.2.Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (homework) all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Written exam weeksth& 15th 14
Assessment 6 Oral exam weeksth& 15th 14
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (homework) 5
2 Practical Exam 25
3. Final-Term Exam 40
3. Oral Exam 10
Total 100%
7. List of References:
No. Reference Type
1.
1.1.Rang and Dale Pharmacology by James Ritter, Rod Flower
Graeme Henderson and Humphrey Rang (Churchill Livingstone;
8th edition, 2015).
1.2. Lippincott Illustrated Reviews: Pharmacology by Karen Whalen
(Lippincott Williams & Wilkins; 6th edition, 2015).
1.3. Brody's Human Pharmacology, Molecular to Clinical; by Lynn
Crespo, Lynn Wecker, George Dunaway, Carl Faingold and
Stephanie Watts (Elsevier Mosby; fifth Edition, 2010)
Textbook
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2.
-British Journal of Pharmacology.
-Pharmacological Reviews.
-Trends in Pharmacological Sciences.
Periodical
3.
www.aspet.org (The American Society for Pharmacology and
Experimental Therapeutics),
www.rxlist.com & www.drugs.com
Website
8. Matrix of course contents versus ILOs:
8.1.Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1.
-Pharmacodynamics
Receptors, efficacy, potency, agonist
and antagonists
a1 b1,b2 c1, c4 --
2.
-Pharmacokinetics
Absorption, distribution, metabolism &
elimination of drugs
a2 b2 c2 --
3. Introduction to autonomic
pharmacology a3 b1 c4 d1,d2
4.
- Acetylcholine receptors agonists and
antagonists
- Neuromuscular blockers
a1,a2,a3 b1 c3,c4 d1,d3
5. Adrenoceptors activating drugs a1,a2,a3 b1 c4 d1,d3
6. Adrenoceptors blocking drugs a1,a2,a3 b1 c4 d1,d3
7. Autacoid and autacoid antagonists a1,a2,a4 b2 c4 d1
9. Drugs acting on respiratory system a1,a2,a4 b1,b2 c4 d1,d2, d3
10. Anti-hypertensive drugs a1,a2,a5 b1, b3 c4 d1,d2, d3
11. Anti-anginal drugs a1,a2,a5 b1, b4 c4 d1,d2, d3
12. Drugs for treatment of congestive heart
failure a1,a2,a5 b1, b5 c4 d1,d2, d3
13. Anti-arrhythmic drugs a1,a2,a5 b1, b5 c4 d1,d2, d3
8.2.Practical:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Handling of animals --- b1 c1, c2,c3 --
2. Routes of drug administration a1, a2 b1 c2, c3 --
21 | P a g e
3. Dose calculation --- b1 c1 --
4. Mice handling and injection -- -- c1, c2 d1,d2
5. Hypnotics a1, a2 -- c1, c2 d1,d2
6. PBL -- -- c4 d1,d2.d3
7. Revision -- b1 c1, c2 d1,d2.d3
9. In-vitro experiments a3 b1 c3 d2
10. Effect of acetylcholine on isolated
rabbit intestine a3 b1 c3 d2
11. Effect of barium chloride on isolated
rabbit intestine a3 b1 c3 d2
12.
Effect of acetylcholine and Bacl2 in
presence of atropine on isolated rabbit
intestine
a3 b1 c3 d2
Name Signature
Course Coordinator: Prof. Dr. Hassan A. El-Kashef
Head of Department: Prof. Dr. Hassan A. El-Kashef
Approval Date 10/9/2017
22 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Pharmacology-2
Course Code: PB 332
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology and Biochemistry
Academic year/ level: Spring semester 2017/2018 Level: 3
Prerequisite: Pharmacology-1 (PB 331)
Credit hours: Lecture: 3 Practical: 1 Total: 4
2. Course Aims:
To provide comprehensive coverage of the major drug groups affecting the central
nervous system and gastrointestinal tract (GIT) together with chemotherapeutic drugs
(antimicrobial and anticancer). To provide knowledge and understanding of the basic
principles of human body control, the activities of endocrine hormones and drug/hormone
therapies of diseases resulting from excess or deficiency of hormones. Moreover, the
adverse effects and toxicity of centrally acting drugs, hormones and chemotherapeutic
drugs are covered.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, students should be able to:
A11 a1 Recognize the etiologies and pathomechanisms of major diseases affecting
the central nervous system (CNS).
A13
a2 Outline the mechanisms of action, clinical uses and adverse effects of
different drugs acting on CNS
a3 Identify basic pharmacological aspects of drugs used in treatment of
gastrointestinal disorders
A14
a4 Discuss the proper therapeutic uses of drugs/hormones in treatment various
disorders resulting from deficiency or overproduction of hormones.
a5 Recognize the effects and clinical uses of chemotherapeutic drugs and their
toxicities
23 | P a g e
b. Intellectual Skills:
At the end of this course, student should be able to:
B9
b1. Assess the drug interactions, adverse reactions and misuse of centrally acting
drugs.
b2. Distinguish between the different classes of hormones and their
pharmacological actions.
b3. Justify the use of antibiotics and chemotherapeutic agents in different
diseases and disorders.
b4
Predict the most clinically important drugs for treatment of emesis,
hyperacidity, peptic ulcer, diarrhea and constipation.
c. Professional and Practical Skills:
At the end of this course, students should be able to:
C11 c1. Handle different laboratory animals to apply various experimental studies
c2. Screen pharmacological effects of different classes of CNS drugs
C13 c3. Utilize the problem-based learning (PBL) to analyze and solve clinical cases
of endocrine and gastrointestinal disorders.
C21 c4. Monitor side effects and toxicities of chemotherapeutic agents.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D1 d1 Communicate effectively in a scientific language with professionals
D3 d2 Work effectively within a team
D6 d3 Develop the skills required for self-learning
D9 d4 Demonstrate time management ability
4. Contents:
4.1.Lectures:
Study week Topics No. of Credit
hours
1 Sedatives, hypnotics and anxiolytics 3
2 Antipsychotic and antidepressant drugs 3
3 Opioid analgesics and anti-inflammatory drugs 3
4 Antiparkinsonian and antiepileptic drugs + (Quiz 1) 3
5 Pituitary gland hormones 3
6 Adrenal cortex hormones 3
7 Pancreatic and thyroid hormones 3
8 Quiz 2
9 Drugs acting on GIT 3
24 | P a g e
10 Antibacterial drugs (cell wall synthesis inhibitors) 3
11 Antibacterial drugs ( inhibitors of protein and nucleic acid
synthesis) 3
12 Antiviral, antifungal, antiprotozoal and anthelmintic drugs 3
13 Anticancer drugs 3
14.
Final Exam Total:
3 credit hours 15.
4.2.Practical:
Study
week Topics
No. of
Credit Hours
1. CNS depressants (barbiturates) 1
2. CNS depressants (benzodiazepines) 1
3. PBL (endocrine disorders) 1
4. Narcotic analgesics 1
5. Non-narcotic analgesics 1
6. PBL (infective disorders) 1
7. CNS stimulants (strychnine) 1
8. Quiz 2
9. CNS stimulants (caffeine) 1
10. Determination of the onset of action of a local anesthetic using
laboratory frogs 1
11. Identification of unknown solution of a local anesthetic using
laboratory frogs 1
12. Revision 1
13. Practical Exam 1
14.
Final Exam Total:
1 credit hour 15.
25 | P a g e
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Practical session
5.3. Group assignments, self-learning
5.4. Case discussions and PBL
5.5. L.M.S
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam To assess professional and practical skills.
3. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
4. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes To assess knowledge, understanding and intellectual skills.
6.2.Assessment schedule:
Assessment 1 Quiz 1 4thweek
Assessment 2 Quiz 2 8thweek
Assessment 3 Assignment/activity (homework) all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Written exam weeksth& 15th 14
Assessment 6 Oral exam weeksth15 &th 14
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (homework) 5
2 Practical Exam 25
3. Final-Term Exam 40
4. Oral Exam 10
Total 100%
26 | P a g e
7. List of References:
No. Reference Type
1.
1.1.Rang and Dale Pharmacology by James Ritter, Rod
Flower Graeme Henderson and Humphrey Rang
(Churchill Livingstone; 8th edition, 2015).
1.2. Lippincott Illustrated Reviews: Pharmacology by Karen
Whalen (Lippincott Williams & Wilkins; 6th edition,
2015).
1.3. Brody's Human Pharmacology, Molecular to Clinical;
by Lynn Crespo, Lynn Wecker, George Dunaway, Carl
Faingold and Stephanie Watts (Elsevier Mosby; fifth
Edition, 2010)
Textbook
2. -British Journal of Pharmacology.
-Pharmacological Reviews.
-Trends in Pharmacological Sciences.
Periodical
3. www.aspet.org (The American Society for Pharmacology
and Experimental Therapeutics),
www.rxlist.com & www.drugs.com
Website
8. Matrix of course contents versus ILOs:
8.1.Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1 Sedatives, hypnotics and anxiolytics a1,a2 b1 c1,c2 --
2 Antipsychotic and antidepressant drugs a1,a2 b1 c1,c2 --
3 Opioid analgesics and anti-
inflammatory drugs a1,a2 b1 c1,c2 d1
4. Antiparkinsonian and antiepileptic
drugs a1,a2 b1 c1,c2 d1,d3
5 Pituitary gland hormones a4 b2 c3 d1, d3
6 Adrenal cortex hormones a4 b2 c3 d1, d3
7. Pancreatic and thyroid hormones a4 b2 c3 d1, d3
9. Drugs acting on GIT a3 b4 c3 d1, d3
10 Antibacterial drugs (cell wall synthesis
inhibitors) a5 b3 c4 d1, d3
11 Antibacterial drugs ( inhibitors of
protein and nucleic acid synthesis) a5 b3 c4 d1, d3
12 Antiviral, antifungal, antiprotozoal and
anthelmintic drugs a5 b3 c4 d1, d3
13 Anticancer drugs a5 b3 c4 d1, d3
27 | P a g e
8.2. Practical:
Study week Course Contents ILOs
K&U IS P&PS G&TS
1-2 CNS depressants a1,a2 b1 c1,c2 --
3. PBL (endocrine disorders) a3 b2 c3 d1, d2, d3
4-5 Analgesics a1,a2 b3 c1,c2 d2, d4
6. PBL (infective disorders) a4 b3 c4 d1, d2, d3
7. CNS stimulants (strychnine) a1,a2 b1 c1,c2 d2, d4
9. CNS stimulants (caffeine) a1,a2 b1 c1,c2 d1, d2, d3
10
Determination of the onset of
action of a local anesthetic using
laboratory frogs
a1,a2 b1 c1 d2, d4
11
Identification of unknown
solution of a local anesthetic
using laboratory frogs
a1,a2 b1 c1 d2, d4
12. Revision a1,a2 b1 c1,c2 d2, d4
Name Signature
Course Coordinator: Dr. Ghada Samy
Head of Department: Prof. Dr. Hassan A. El-Kashef
Approval Date 6/2/2018
28 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Toxicology
Course Code: PB 421
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology & Biochemistry
Academic year/ level: Spring semester 2017/2018 Level four
Prerequisite: Pharmacology 2 (PB 332)
Credit hours: Lecture: 2 Practical: 0 Total: 2
2. Course Aims:
To understand basic principles and different disciplines of toxicology. To gain knowledge
regarding first aid measures, supportive measures, therapeutic interventions, specific antidotes
as well as general guidelines of treatment modalities. To gain knowledge and understanding
of the mechanisms of toxicity and toxicokinetics of different types of pesticides, heavy
metals, toxic gases and irritant toxins. To understand the serious consequences of exposure to
therapeutic drugs, environmental and occupational chemicals and develop approaches for
prevention, diagnosis and treatment of adverse effects.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, students should be able to:
A1
a1. Identify different fields of toxicology, including occupational, forensic and
environmental toxicology and general principles of poisoning management.
a2.
Describe the mechanisms of toxicity and toxic effects of certain medications
and environmental pollutants and their selective toxicities on specific target
organs.
A16
a3. Recognize different classes of physical and chemical hazards
a4. Outline toxic profile of various drugs and other xenobiotics including
sources, identification, symptoms, management and first aid measures.
a5. Describe the biological effects of exposure to different types of immunotoxic
and carcinogenic agents.
29 | P a g e
b. Intellectual Skills:
At the end of this course, students should be able to:
B11
b1. Differentiate between different toxic agents regarding their symptoms, mode
of actions as well as the main lines of toxicity management.
b2. Adapt the knowledge of patient stabilization and antidotes in management of
toxicity cases.
b3. Interpret information about hazards of different pollutants, xenobiotic, heavy
metals, irritant substances and solvents.
b4. Evaluate drug interactions and adverse drug reactions.
B15 b5. Analyze and evaluate reports of toxicity cases.
c. Professional and Practical Skills:
At the end of this course, students should be able to:
C7 c1. Manage minor illnesses and differentiate from toxicity cases requiring
prompt medical intervention.
C21
c2. Examine toxicity profiles of different xenobiotics and utilize information in
the selection of management protocols.
c3. Measure and analyze risks concerning drug-drug interactions, adverse
reactions and toxicity profiles.
c4. Conduct the safe and effective use of drugs in patients while managing the
toxicity condition.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1. Communicate and work effectively in a team.
D5 d2. Implement online computer searching to develop information technology
skills from a variety of sources.
D12 d3. Demonstrate rational thinking and decision-making abilities
4. Contents:
4.1.Lectures:
Study
week Topics
No. of
Credit Hours
1. Introduction 2
2. Mechanisms of toxicity 2
3. Target organ toxicity 2
4. Air, soil and water pollution + (quiz 1) 2
5. Metal toxicity 2
6. Liver toxicity 2
7. Hematotoxicity 2
8. Quiz 2
9. Carcinogenesis (stages of carcinogenesis and carcinogens) 2
30 | P a g e
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Seminars
5.3. Group assignments and self-learning activities
5.4. Case study discussion
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Course work To assess knowledge, understanding, intellectual skills, general &
transferable skills.
3. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
4. Quizzes To assess knowledge, understanding and intellectual skills.
6.2.Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment all over the term
Assessment 4 Written exam 14th & 15th weeks
Assessment 5 Oral exam 14th & 15th weeks
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment 5
2. Final-Term Exam 65
3. Oral Exam 10
Total 100%
10. Carcinogenesis (oncogenes and tumor suppressor genes) 2
11. Pulmonary toxicity 2
12. Kidney toxicity + case study 2
13. Immunotoxicity 2
14. Final Exam
Total:
2 credit hours 15.
31 | P a g e
7. List of References:
No. Reference Type
1. Casarett & Doull's Toxicology: The Basic Science of Poisons, by
Curtis Klaassen. (McGraw-Hill Education; 8th edition, 2013 Textbook
2. Journal of Toxicological Sciences; Journal of Toxicology and
Applied Pharmacology Periodical
3. TOXNET (https://toxnet.nlm.nih.gov/) Website
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
Week Course Contents
ILOs
K&U IS P&PS G&TS
1. Introduction
a1, a2 b1, b2 c1 --
2. Mechanisms of toxicity a2, a3 b1, b3 c1 --
3. Target organ Toxicity
a2, a3 b1,b3 c1, c2 d2,d3
4. Air, soil and water pollution a1, a2,
a3 b1, b3 c3 d2,d3
5. Metal Toxicity
a2, a4 b1, b2, b3 c1, c2,
c4 d1,d2,d3
6. Liver Toxicity
a2, a4 b1, b4 c3,c2,c4 d2,d3
7. Hematotoxicity
a2, a4 b1, b4 c2,c3,c4 d2,d3
9. Carcinogenesis ( stages of
carcinogenesis and carcinogens) a2, a4,
a5 b1, b3 c1, c2,c3 d1,d2
10. Carcinogenesis ( oncogenes and
tumor suppressor genes ) a2, a4,
a5 b1, b3 c1, c2,c3 d1,d2
11. Pulmonary Toxicity
a2, a4 b1, b4 c2,c3,c4 d2,d3
12. Kidney Toxicity + case study
a2, a4 b1, b4, b5 c2,c3,c4 d2,d3
13. Immunotoxicity a2, a4,
a5 b1, b4 c2,c3,c4 d2,d3
Name Signature
Course Coordinator: Dr. Amany Abdelmegid
Head of Department: Prof. Dr. Hassan A. Elkashef
Approval Date 6/2/2018
32 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Biostatistics
Course Code: PB 542
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology & Biochemistry
Academic year/ level: Spring Semester 2017/2018 Level Five
Prerequisite: None
Credit hours: Lecture: 2 Practical: 0 Total: 2
2. Course Aims:
To enhance the student’s ability in problem solving, experimental design, and evaluation of
clinical trials data; as well as, to use statistical methods in collection and presentation of data.
The course provides knowledge about estimation of the drug’s effects on different body
organs and tissues.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, students should be able to:
A1 a1. Recognize basic concepts of biostatistics and data analysis.
a2. Describe the principles of basic science in the field of biological assay.
A17
a3. Mention methods of statistical analysis and pharmaceutical calculations in an
efficient manner for handling data.
a4. Identify ways of drug screening on experimental animals to determine the
mechanisms of action.
a5. Recall methods of drug bioassay on experimental animals to estimate the
potency of drugs.
b. Intellectual Skills:
At the end of this course, student should be able to:
B13
b1. Predict role of biostatistics in medical research.
b2. Interpret the meaning of different data presentation types.
b3. Analyze critically the data derived from laboratory and clinical
measurements.
b4. Compare the potency of the test and standard preparations used in bioassay
procedures based on the statistical results.
b5. Assess the main steps in screening and biological standardization of different
substances based on their physiological function or toxic effects.
33 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C11
c1. Select appropriate statistical tests and use results of applied statistics to make
informed decisions.
c2. Apply methods of graphical presentation.
c3. Discriminate between various experimental models to select the best one
used for biological assay.
c4. Design complete experimental protocols for biological standardization of
different compounds.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1. Work effectively within a team.
D4 d2. Collect, evaluate and present data in accordance with standard statistical
methods.
D11 d3. Search the internet for updates of statistical problem-solving methods and
concepts related to the probability, screening and bioassays.
4. Contents:
4.1.Lectures:
Study
week Topics
No. of
Credit Hours
1. Introduction of statistics + strategies to understand the
meaning of data (descriptive statistics) 2
2.
Measures of central tendency (mean, median, mode) +
measures of dispersion (range, variance and standard
deviation)
2
3. Hypothesis testing (one sample t-test) 2
4. Hypothesis testing (Unpaired and paired student t-test) +
Quiz 1 2
5. Hypothesis testing (ANOVA test) and Chi-X2 test 2
6. Correlation, regression, measures of mortality and morbidity
and non-parametric tests. 2
7. Applications (Exercise + PBL) 2
8. Quiz 2
9. Screening and bioassay of autonomic drugs 2
10. Screening and bioassay of skeletal muscle relaxants 2
11. Screening and bioassay of analgesics, anti-inflammatory
drugs and local anesthetics 2
12. Screening and bioassay of insulin and cardiac glycosides 2
13. Screening and bioassay of antihypertensive drugs 2
14. Final Exam
Total:
2 credit
hours 15.
34 | P a g e
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Assignments, Self-learning
5.3. PBL
5.4. L.M.S (Moodle)
5. Student Assessment Methods:
5.1.Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional skills.
2. Course work To assess knowledge, understanding, intellectual, professional and
general& transferable skills.
3. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
4. Quizzes To assess knowledge, understanding and intellectual skills.
5.2.Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignments (presentation) all over the term
Assessment 4 Oral exam 14th & 15th weeks
Assessment 5 Written exam 14th & 15th weeks
5.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment (presentation) 5
2. Final-Term Exam 65
3. Oral Exam 10
Total 100%
6. List of References:
No. Reference Type
1.
A- Biostatistics, Basic concepts and methodology for the health
sciences, 10th Edition, Wiley (2014)
B- Drug discovery and evaluation: Pharmacologic assays, Vogel
and Vogel (2013), Springer.
C- Basic and Clinical Biostatistics, Beth D. Saunders, Robert G.
Trapp; (2012), McGraw-Hill publishing Company.
Textbook
2 Statistical Methods in Medical Research
(https://journals.sagepub.com/home/smm) Periodical
35 | P a g e
7. Matrix of course contents versus ILOs:
7.1.Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1.
Introduction of statistics + strategies to
understand the meaning of data
(descriptive statistics)
a1 b1 c2 --
2.
Measures of central tendency (mean,
median, mode) + measures of
dispersion (range, variance and
standard deviation)
a1 b1,b2 -- --
3. Hypothesis testing (one sample t-test) a3 b3 c1 --
4. Hypothesis testing (Unpaired and
paired student t-test) a3 b3 c1 d2
5. Hypothesis testing (ANOVA test) and
Chi-X2 test a3 b3 c1 d2
6.
Correlation, regression, measures of
mortality and morbidity and non-
parametric tests.
a3 b3 c1 d1,d2
7. Applications (Exercise + PBL) a1,a3 b3 c1,c2 d1,d2
9. Screening and bioassay of autonomic
drugs a2,a4,a5 b4,b5 c3,c4 d3
10. Screening and bioassay of skeletal
muscle relaxants a4,a5 b4 c3,c4 d3
11.
Screening and bioassay of analgesics,
anti-inflammatory drugs and local
anesthetics
a2,a5 b4 c3,c4 d3
12. Screening and bioassay of insulin and
cardiac glycosides a4,a5 b4,b5 c4 d3
13. Screening and bioassay of
antihypertensive drugs a4,a5 b4,b5 c4 d3
Name Signature
Course Coordinator: Dr. Ahmed Esam Khodir
Head of Department: Prof. Dr. Hassan A. Elkashef
Approval Date 6/2/2018
36 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: OTC abuse
Course Code: PB 435
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology and biochemistry
Academic year/ level: Fall Semester 2017/2018 Level 4.
Prerequisite: None
Credit hours: Lecture: 2 Practical: 0 Total:2
2. Course Aims:
To provide an overview of the basic concepts of drug abuse and the necessary knowledge
about different classes of over the counter (OTC) drugs of great abuse susceptibility. The
course provides further information about the driving forces and the different reasons of abuse
in addition to the major signs and symptoms of drug toxicity and abuse. Furthermore, the
course outlines the methods of prevention of drug misuse.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A1 a1. Identify the basic pharmaceutical drugs abused and their impact on health
A16
a2. Recognize the toxic profile of cough suppressant and decongestant drugs.
a3. Define the symptoms and measures of prevention of drug misuse.
a4. Differentiate between symptoms of abuse of caffeine, hypnotics and opiate
drugs
a5. List main classes of abused drugs.
b. Intellectual Skills:
At the end of this course, student should be able to:
B15
b1. Estimate health hazards concerning drug abuse.
b2. Predict vulnerabilities concerning drug misuse and exposure to toxic agents.
b3. Analyze the symptoms of drug abuse.
b4. Assess the legal regulations concerning abuse of drugs
37 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C9
c1. Raise public awareness on rational use of drugs.
c2. Monitor social health hazards of drug abuse and misuse.
c3. Manipulate different risks concerning drug misuse.
C10 c4. Counsel patients about safe use of OTC medications
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1 Work effectively within a team frame.
D6 d2 Develop the skills required for self-learning
4. Contents:
4.1.Lectures:
4.2.Practical: Not Applicable
5. Teaching and Learning Methods:
5.1. Lectures.
5.2. Self-learning.
5.3. Activity/assignments ( homework)
5.4. L.M.S.
Study
week Topics
No. of
Credit Hours
1. Introduction to drug abuse 2
2. Cough suppressant (dextromethorphan) abuse 2
3. Decongestant (pseudoephedrine) abuse 2
4. Laxative abuse + Quiz 1 2
5. Antihistamine abuse 2
6. Diet pills abuse 2
7. Caffeine abuse 2
8. Quiz 2
9. Abuse of sedatives and hypnotics 2
10. Abuse of opioids 2
11. Abuse of acetaminophen 2
12. Abuse of NSAIDs 2
13. Abuse of amphetamine 2
14. Final Exam
Total:
2 credit hours 15.
38 | P a g e
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
3. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
4. Quizzes To assess knowledge, understanding and intellectual skills.
6.2.Assessment schedule:
Assessment 1 Quiz 1 4thweek
Assessment 2 Quiz 2 8thweek
Assessment 3 Assignment (homework) all over the term
Assessment 4 Written exam 14th&15thweeks
Assessment 5 Oral exam weeksth& 15th 14
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment 5
2. Final-Term Exam 65
3. Oral Exam 10
Total 100%
7. List of References:
No. Reference Type
1. Abusing Over-the-Counter Drugs: Illicit Uses for Everyday Drugs
(Illicit and Misused Drugs) by Kim Etingoff 2012 Textbook
2 https://drugabuse.com/library/otc-drug-abuse/ Website
8. Matrix of course contents versus ILOs:
8.1.Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Introduction to drug abuse a1, a5 b1, b4 c1 --
2. Cough suppressant (dextromethorphan)
abuse a2, a3 b2, b3 c2, c4
--
3. Decongestant (pseudoephedrine) abuse a2, a3 b2, b3 c3, c4 d1,d2
39 | P a g e
4. Laxative abuse a3 b2, b3 c3, c4 d1,d2
5. Antihistamine abuse a3, a5 b2, b3 c3, c4 d1,d2
6. Diet pills abuse a3 b2, b3 c2, c4 d1,d2
7. Caffeine abuse a3, a4 b2, b3 c3, c4 d1,d2
9. Abuse of sedatives and hypnotics a3, a4
b2, b3 c2,c3, c4 d1,d2
10. Abuse of opioids a3, a4
b3, b4 c2, c3 d1,d2
11. Abuse of acetaminophen a3 b2, b3 c3, c4 d1,d2
12. Abuse of NSAIDs a3, a5 b2, b3 c3, c4 d1,d2
13. Abuse of amphetamine a3 b2, b3 c2,c4 d1,d2
Name Signature
Course Coordinator: Dr. Eman Mahmoud
Head of Department: Prof. Dr. Hassan El Kashef
Approval Date 10/9/2017
40 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: General Biology
Course Code: PB 101
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology and Biochemistry
Academic year/ level: Fall Semester 2017/2018 Level 1
Prerequisite: None
Credit hours: Lecture: 2 Practical: 0 Total: 2
2. Course Aims:
The course provides the basic principles of biology and taxonomy, classification of
prokaryotes and eukaryotes with an emphasis on cellular structure. It describes the functions
of organelles and regulatory mechanisms in animal cells.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A1
a1. Identify the fundamental concepts of biology, taxonomy with an emphasis on
animal cell structure and function.
a2. Describe the basic characteristics of prokaryotic and eukaryotic cells and
extracellular matrix.
A4 a3. Enumerate the theories of transport across the biological membranes.
A11 a4.
Recall the basic principles of cellular function, including cell communication,
ligands and receptors.
a5 Describe cell death mechanisms in normal and cancer cells.
b. Intellectual Skills:
At the end of this course, student should be able to:
B18
b1. Correlate cell structure with its function, including active and passive
transport across membrane.
b2. Integrate basic biochemical facts with mechanisms of apoptosis of normal
cells and tumor formation.
b3. Investigate the characteristics of living things to classify organisms into
eukaryotes and prokaryotes.
41 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C1 c1. Utilize gained information to communicate with other health care professionals
C11 c2.
Apply biology knowledge to practical scientific activities and relevant
applications of biology in society and the environment.
c3. Conduct research studies including presentation skills and discussion
C13 c4. Monitor risks concerning incompatibilities in drug substances with
regulatory signals of cell cycle leading to necrosis or apoptosis
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1. Work effectively as a part of a team to perform the required tasks.
D4 d2. Collect, evaluate and present data.
D6 d3. Develop the skills required for continued self-professional development and
self-learning.
4. Contents:
4.1.Lectures:
Study
week Topics
No. of
Credit Hours
1. Introduction to biology; characteristics of living things 2
2. Classification of organisms; principles of taxonomy 2
3. Prokaryotes versus eukaryotes ; animal cell structure 2
4. Organelles functions + quiz 1 2
5. Biological membranes structure and function 2
6. Membrane passive transport and osmosis 2
7. Membrane active transport 2
8. Quiz 2
9. Cytoskeleton and extracellular matrix 2
10. Communication between cells 2
11. Ligands and receptors 2
12. Apoptosis and tumors 2
13. Revision
14. Final Exam
Total:
2 credit hours 15.
42 | P a g e
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Research in library and web (homework and assignments)
5.3. Presentation of research topics
5.4 Discussion
5.5 E-learning using MOODLE system
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam to assess knowledge, understanding, intellectual and professional
skills.
2. Course work to assess knowledge, understanding, intellectual skills, general &
transferable skills.
3. Quizzes to assess knowledge, understanding and intellectual skills.
6.2.Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (Research) all over the term
Assessment 4 Written exam 14th & 15th weeks
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (Research.) 5
2. Final-Term Exam 75
Total 100%
7. List of References:
No. Reference Type
1. Lippincott Illustrated Reviews: Cell and Molecular Biology by Nalini
Chandar and Susan Viselli 1st Edition (Lippincott Illustrated Reviews
Series, 2010)
textbook
2. Cell Biology and Histology by Gartner, Leslie P., Hiatt, James L.,
Strum, Judy, 5th Edition [Lippincott Williams & Wilkins, 2006] textbook
3. Biology, Peter H. Raven. [McGraw-Hill Education; 11th edition
(2016)] Online Book
43 | P a g e
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1.
Introduction to biology; Characteristics
of living things a1
b1
b3
c1
c2 --
2. Classification of organisms; Principles
of taxonomy a1 b3 c1 --
3. Prokaryotes versus and Eukaryotes;
Animal cell structure a2
b1
b3 c2 d3
4. Organelles functions a1
a4
b1
b3
c2
c3
d1
d2
5. Biological membranes structure and
function
a3
a4 b1
c1
c2 d3
6. Membrane passive transport and
osmosis
a3
a4 b1 c2 d3
7. Membrane active transport a3
a4 b1
c2
c3
d1
d2
8. Quiz 2
9. Cytoskeleton and extracellular matrix a2
a4 b1
c2
c3
d1
d2
10. Communication between cells a4 b1
b2
c2
c4 d3
11. Ligands and receptors a4 b1
b2 c4 d3
12 Apoptosis and Tumors a5
b2
c4 d3
Name Signature
Course Coordinator: Dr. Rania Khalil
Head of Department: Prof. Dr. Hassan El Kashif
Approval Date 10/9/2017
44 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Biochemistry-1
Course Code: PB 221
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology and Biochemistry
Academic year/ level: Fall Semester 2017/2018 Level 2
Prerequisite: Physical Chemistry (PC 102)
Credit hours: Lecture: 2 Practical: 1 Total: 3
2. Course Aims:
The course aims to understand the basic principles of biochemistry and its importance for
living organisms and integrates chemical structure of macromolecules (carbohydrates,
proteins, lipids) with its functions. It describes the general characters of enzymes, functions,
mechanisms of action, kinetics, and regulation. It explains concepts as vitamins, porphyrins
and biological oxidation.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A1 a1. Identify the basic principles of biochemistry, including chemistry of
carbohydrates and their classification, structure and function.
A4
a2. List the chemical structures of proteins and lipids macronutrients and
illustrate their functions.
a3. Enumerate the theories of enzyme action, enzymes inhibition and the role of
enzymes in disease diagnosis.
a4.
Describe vitamins; chemical structure, function, properties and deficiency
problems, and recognize porphyrins, biological oxidation and electron
transport chain.
b. Intellectual Skills:
At the end of this course, student should be able to:
B18
b1 Correlate basic biochemical facts of carbohydrates with its importance in the
formation of nucleic acid and immune response in the body.
b2. Evaluate the importance of lipids as precursor of prostaglandins, leukotrienes
and thromboxane
b3. Integrate basic biochemical facts concerning body peptides, proteins and
enzymes with its role in human body functions.
45 | P a g e
B21 b4. Predict symptoms end effects of vitamins deficiencies in a given case study
report.
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C2 c1. Handle and dispose laboratory reagents safely using instruments in biochemistry
laboratory
C11 c2.
Conduct research studies concerning important molecules (lipoproteins,
porphyrins, mucopolysaccharides) in the body including presentation, and
interpretation of biochemical data.
C14 c3. Employ different qualitative diagnostic tests for different types of carbohydrates
and proteins
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1. Work effectively as a part of a team to perform the required tasks.
D4 d2. Collect, evaluate and present data.
D6 d3. Develop the skills required for continued self-professional development and
self-learning.
4. Contents:
4.1. Lectures:
Study
week Topics
No. of
Credit Hours
1. Basic principles of carbohydrates chemistry;
monosaccharaides structure and function 2
2. Disaccharides chemistry 2
3. Polysaccharides chemistry 2
4. Simple lipids chemistry + Quiz 1 2
5. Complex lipids chemistry ; function in biological membrane 2
6. Lipoproteins 2
7. Amino acids and protein chemistry 2
8. Quiz 2
9. Porphyrins 2
10. Enzymes 2
11. Vitamins 2
12. Biological oxidation and electron transport chain 2
13. Revision 2
14. Final Exam
Total:
2 credit hours 15.
46 | P a g e
4.2. Practical:
Study
week Topics
No. of
Credit Hours
1. Introduction, handling processes & safety
Qualitative determination of monosaccarides; glucose 1
2. Qualitative determination of monosaccarides; fructose 1
3. Qualitative determination of disaccharides; sucrose 1
4. Qualitative determination of disaccharides; lactose and maltose
+ Quiz 1 1
5. Qualitative determination of polysaccharides; starch 1
6. Qualitative determination of polysaccharides; dextrin 1
7. Qualitative determination of albumin 1
8. Quiz 2
9. Qualitative determination of neutral proteins; peptone 1
10. Qualitative determination of neutral proteins; gelatin 1
11. Qualitative determination of alkaline proteins; metaprotein 1
12. Qualitative determination of alkaline proteins; Caseinogen 1
13. Practical Exam 1
14. Final Exam
Total:
1 credit hour 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Practical lab
5.3 Research in library and web (homework & assignments)
5.4 E-learning (Moodle system)
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam to assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam to assess professional and practical skills.
3. Course work to assess knowledge, understanding, intellectual skills, general &
transferable skills.
4. Oral exam to assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes to assess knowledge, understanding and intellectual skills.
47 | P a g e
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (Research, assignment
using electronic system (Moodle)) all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Oral exam 14th & 15th weeks
Assessment 6 Written exam 14th & 15th weeks
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (Research, assignment using electronic
system (Moodle)) 5
2. Final-Term Exam 40
3. Oral Exam 10
4. Practical Exam 25
Total 100%
7. List of References:
No. Reference Type
1. Biochemistry (Lippincott Illustrated Reviews Series) by Denise R.
Ferrier (Lippincott Williams & Wilkins; 6th Edition, 2013) Textbook
2. Biochemistry, Mary K. Campbell, Shawn O. Farrell. Thomson
Brooks/Cole 2014, 8th Edition
Textbook
3. Medical biochemistry by M.D. Chatterjea and Shinde Rana (Jaypee
Brothers Medical Pub; 8th edition, 2011)
Textbook
4. Clinical Chemistry by W. J. Marshall, Márta Lapsley (8th Edition,
2016).
Textbook
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1.
Basic principles of carbohydrates
chemistry; monosaccharaides structure
and function
a1 b1 c3 --
2. Disaccharides chemistry a1 b1 c3 --
3. Polysaccharides chemistry a1 b1 c2 d1,d2
48 | P a g e
4. Simple lipids chemistry a2 b2 -- d1,d2
5. Complex lipids chemistry ; function in
biological membrane a2 b2 c2 d2
6. Lipoproteins a2 b2 c2 d2
7. Amino acids and protein chemistry a2 b3 c3 d2
d3
9. Porphyrins a4 b3 c2 d1
d2
10. Enzymes a3 b3 -- d3
11. Vitamins a4 b4 -- d1
d2
12. Biological oxidation and electron
transport chain a4 -- -- d3
8.2.Practical:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1.
Introduction, handling processes &
safety
Qualitative determination of
monosaccarides; glucose
a1 b1 c1 --
2. Qualitative determination of
monosaccarides; fructose a1 b1 c1,c3 --
3. Qualitative determination of
disaccharides; sucrose a1 b1 c3 d1
4. Qualitative determination of
disaccharides; lactose and maltose a1 b1 c3 d1,d2
5. Qualitative determination of
polysaccharides; starch a1
b1
c2,c3 d1-d3
6. Qualitative determination of
polysaccharides; dextrin a1
b1
c2,c3 d1-d3
7. Qualitative determination of albumin a2
b3 c1,c3 d1,d3
9. Qualitative determination of neutral
proteins; peptone a2 b3 c3 d1,d3
49 | P a g e
10. Qualitative determination of neutral
proteins; gelatin a2 b3 c3 d1,d3
11. Qualitative determination of alkaline
proteins; metaprotein a2 b3 c3 d1,d3
12. Qualitative determination of alkaline
proteins; Caseinogen a2 b3 c3 d1,d3
Name Signature
Course Coordinator: Dr. Samuel Tanas
Head of Department: Prof. Dr. Hassan El Kashif
Approval Date 10/9/2017
50 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Biochemistry-2
Course Code: PB 222
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology and Biochemistry
Academic year/ level: Spring Semester 2017/2018 Level 2
Prerequisite: Biochemistry-1 (PB 221)
Credit hours: Lecture:2 Practical:1 Total: 3
2. Course Aims:
This course explains how biochemistry relates to wellness and disease processes and its direct
relationship to understanding pharmaceutical principles. The course describes the biosynthetic
processes leading to the generation of macromolecules and the regulatory processes
underlying its biosynthesis and their function in cellular systems. It identifies intermediary
metabolism in terms of energy production and maintaining cellular homeostasis. Integration
between metabolic control and biochemical disorders is also considered.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A1
a1. Identify the principles of metabolism and recall the essential facts and
advanced concepts of digestion and absorption.
a2.
Describe the functions and metabolic pathways of macromolecules
(carbohydrates , lipids, proteins) and their hormonal and non-hormonal
regulatory mechanisms
A4 a3.
Enumerate metabolic disorders that have biochemical and clinical
implications, and describe biologically active compounds synthetized from
amino acids
A11 a4.
Describe the biochemical basis of some diseases, including diabetes
mellitus, glycogen storage diseases and outlines the fate of biological
compounds.
51 | P a g e
b. Intellectual Skills:
At the end of this course, student should be able to:
B14 b1. Evaluate evidence-based biomedical information and investigate the
metabolic disturbance in a given case study report.
B17
b2.
Determine suitable methods of analysis of different levels of glucose, total
proteins, ALT, AST, bilirubin, albumin, cholesterol, TG, creatinine and uric
acid in biological fluids
b3. Formulate a systemic approach for the laboratory experimental diagnosis
B18 b4. Correlate basic biochemical facts in cases of liver and kidney diseases with
laboratory data.
B21 b5. Interpret laboratory tests with the impact of signs and symptoms in case of
metabolic disorders.
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C2 c1. Handle and dispose laboratory reagents and biological specimen safely
utilizing instruments used in biochemistry laboratory
C4 c2.
Select appropriate methods for identification and analysis of active
substances in biological fluids (colorimetric estimation using
spectrophotometer)
C14 c3.
Employ different quantitative diagnostic tests of some blood parameters
(serum levels of glucose, total proteins, albumin, bilirubin, ALT, AST,
cholesterol, TG, creatinine and uric acid).
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1. Work effectively as a part of a team to perform the required tasks.
D4 d2. Collect, evaluate and present data.
D6 d3. Develop the skills required for continued self-professional development and
self-learning.
4. Contents:
4.1.Lectures:
Study
week Topics
No. of
Credit Hours
1. Introduction to metabolism; Carbohydrate digestion and
absorption 2
2. Oxidation of glucose; Glycolysis 2
3. Gluconeogenesis 2
4. Krebs cycle + Quiz 1 2
5. Pentose phosphate pathway 2
52 | P a g e
4.2.Practical:
Study
week Topics
No. of
Credit Hours
1. Introduction, handling processes and safety 1
2. Determination of blood glucose level 1
3. Liver function, albumin and total protein determination 1
4. Bilirubin determination 1
5. Urea and uric acid determination 1
6. Kidney function; creatinine determination 1
7. Lipid profile; Cholesterol determination 1
8. Quiz 2
9. Lipid profile; Triglyceride determination 1
10. Urine analysis 1
11. Calcium determination 1
12. Revision 1
13. Practical Exam 1
14. Final Exam
Total:
1 credit hour 15.
6. Glycogenesis and Glycogenolysis 2
7. Fatty acids synthesis 2
8. Quiz 2
9. Beta oxidation of fatty acids 2
10. Ketogenesis and ketolysis 2
11. Amino acids synthesis and degredation 2
12. Nitrogenous compounds metabolism and urea cycle 2
13. Biologically active compounds synthesized from amino acids 2
14. Final Exam
Total:
2 credit hours 15.
53 | P a g e
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Practical lab
5.3. Research in library and web (homework and assignments)
5.4. Cases study
5.5 E-learning using Moodle system
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam to assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam to assess professional and practical skills.
3. Course work to assess knowledge, understanding, intellectual skills, general and
transferable skills.
4. Oral exam to assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes to assess knowledge, understanding and intellectual skills.
6.2.Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3
Assignment/activity (Assignments on the
electronic system (Moodle), schematic diagram
poster and case study)
all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Oral exam 14th & 15th weeks
Assessment 6 Written exam 14th & 15th weeks
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (Assignments on the electronic system
(Moodle), schematic diagram poster and case study) 5
2. Final-Term Exam 40
3. Oral Exam 10
4. Practical Exam 25
Total 100%
54 | P a g e
7. List of References:
No. Reference Type
1. Biochemistry (Lippincott Illustrated Reviews Series) by Denise R.
Ferrier (Lippincott Williams & Wilkins; 6th Edition, 2013) Textbook
2. Biochemistry, Mary K. Campbell, Shawn O. Farrell. Thomson
Brooks/Cole 2014, 8th Edition Textbook
3. Medical biochemistry by M.D. Chatterjea and Shinde Rana (Jaypee
Brothers Medical Pub; 8th edition, 2011) Textbook
4. Clinical Chemistry, by W.J. Marshall, Márta Lapsley (8th Edition,
2016). Textbook
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1.
Introduction to metabolism;
Carbohydrate digestion and
absorption
a1 b1 -- --
2. Oxidation of glucose; Glycolysis a2,a3 b2,b3 c2 d3
3. Gluconeogenesis a2,a3 b2,b3 c2 d3
4. Krebs cycle a2,a3 b1,b2 c3 d2
5. Pentose phosphate pathway a3,a4 b1 c3 d2
6. Glycogenesis and Glycogenolysis a3,a4 b3,b4,b5 c2 d3
7. Fatty acids synthesis a2 b2,b3,b4 c2 d1
d2
9. Beta oxidation of fatty acids a2,a3 b2,b3,b5 c3 d1
d2
10. Ketogenesis and ketolysis a2,a3 b2,b3, b5 c3 d1,d3
11. Amino acids synthesis and
degredation a2,a3 b1 c2 d1
12. Nitrogenous compounds catabolism
and urea cycle a3,a4 b3, b5 c3 d1
13. Biologically active compounds
synthesized from amino acids a3 b2,b4 c3
d1
55 | P a g e
8.2. Practical:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Introduction, handling processes and
safety
a1
--
c1
c2 --
2. Determination of blood glucose level a4
b2
c2
c3 d1
3. Liver function, albumin and total
protein determination
a3
a4
b2
b4
c2
c3 d1
4. Bilirubin determination a3
a4
b2
b4 c3 d1,d2
5. Urea and uric acid determination a3
a4
b2
b4 c3 d1,d2
6. Kidney function; creatinine
determination
a3
a4
b2
b4
c2
c3 d1,d3
7. Lipid profile; Cholesterol
determination
a2
a3
b1
b2
b3
c3 d2,d3
9. Lipid profile; Triglyceride
determination
a2
a3
b1
b2
b3
c3 d2,d3
10. Urine analysis -- b2
b4
c2
c3 d2,d3
11. Calcium determination a3
a4 b5 c3 d2,d3
Name Signature
Course Coordinator: Dr. Hanan Hafila
Head of Department: Prof. Dr. Hassan El Kashif
Approval Date 6/2/2018
56 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Clinical Biochemistry
Course Code: PB 422
Program on which the course is given: B. Pharm.
Department offering the course: Pharmacology and Biochemistry
Academic year/ level: Spring Semester 2017/2018 Level 4
Prerequisite: Biochemistry-2 (PB 222)
Credit hours: Lecture:2 Practical: 0 Total:2
2. Course Aims:
This course provides an overview of how biochemical investigations are employed to develop a
clinical diagnosis. To understand the biochemical changes accompanied to metabolic disorders
and the role of endocrine system in its regulation. It describes disorders of liver and kidney
functions with its various diagnostic tests. It illustrates clinical enzymology, tumor markers and
different techniques and devices used in in clinical biochemistry laboratory.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A1
a1. Describe major concepts and applications of clinical biochemistry.
a2.
Recognize the functions and blood levels of hormones, including adrenal
gland, thyroid gland, pituitary gland, gonads and insulin hormone, in health
and disease state.
A11
a3.
Define the principles of laboratory diagnosis (the reference range) and
clinical aspects of different disorders in cases of liver, kidney and blood
diseases.
a4. Recall main enzymes used as diagnostic markers in different diseases
a5 Define tumor markers and outline the most common tumor markers used for
laboratory diagnosis of different malignancies.
b. Intellectual Skills:
At the end of this course, student should be able to:
B13 b1. Interpret laboratory results based on relevant biochemical principles.
B14 b2. Evaluate evidence-based information (complete blood counts and blood
indices) needed in clinical decisions.
57 | P a g e
B17 b3.
Formulate a systemic approach for the laboratory clinical diagnosis using
clinical enzymology and tumor markers in liver, kidney and endocrine
disorders
B18 b4. Integrate basic biochemical and physiological facts in cancer with clinical
data
B21 b5. Interpret clinical laboratory tests in liver, kidney and endocrine disorders
with the impact of clinical symptoms.
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C1 c1.
Utilize the proper information about endocrine system, clinical enzymology
and complete blood counts to communicate with other health care
professionals
C5 c2.
Apply good pharmacy practice by proper understanding of human
physiology and pathophysiology of endocrine system disorders, cancer, liver
and kidney disease.
C11 c3. Conduct scientific research using internet materials followed by presentation,
analysis and interpretation of the results.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1. Work effectively as a part of a team to perform the required tasks
D6 d2. Develop skills required for self-learning
D11 d3. Generate effective and reasonable solutions for rising problems based on the
available information.
4. Contents:
4.1.Lectures:
Study
week Topics
No. of
Credit Hours
1. Endocrine system: overview 2
2. Thyroid gland and its disorders 2
3. Male and female Reproductive system and their disorders 2
4. Male and Female infertility; hormonal profile and semen
analysis + Quiz 1 2
5. Kidney diseases and Kidney function tests 2
6. Liver biochemical role; its disorders and liver function tests 2
7. Anterior Pituitary gland and its disorders 2
8. Quiz 2
9. Posterior Pituitary gland and its disorders 2
10. Clinical Enzymology 2
58 | P a g e
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Research in library and web (homework and assignments)
5.3. Discussion
5.4. Case study (tutorial classes)
5.5. E- learning using Moodle system
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam to assess knowledge, understanding, intellectual and professional
skills.
2. Course work to assess knowledge, understanding, intellectual skills, general &
transferable skills.
3. Oral exam to assess knowledge, understanding, intellectual skills, general skills
and confidence.
4. Quizzes to assess knowledge, understanding and intellectual skills.
6.2.Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (case study) all over the term
Assessment 4 Oral exam 14th & 15th weeks
Assessment 5 Written exam 14th & 15th weeks
6.3.Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (case study) 5
2. Final-Term Exam 65
3. Oral Exam 10
Total 100%
11. Tumor markers 2
12. Adrenal glands and its disorders 2
13. Complete blood counts and blood indices 2
14. Final Exam
Total:
2 credit hours 15.
59 | P a g e
7. List of References:
No. Reference Type
1.
Tietz Fundamentals of Clinical Chemistry and Molecular
Diagnostics by Carl A. Burtis, and David E. Bruns, editors.
(St. Louis, MO: Elsevier Saunders; 7th edition, 2014).
Bishop Textbook for Clinical Chemistry principles,
techniques and correlations by Michael L. Bishop , Edward P.
Fody and Larry E. Schoeff (Lippincott Williams & Wilkins;
7th edition, 2013).
Clinical biochemistry: An Illustrated Color Text, By Allan
Gaw Michael Murphy Rajeev Srivastava Robert Cowan
Denis O'Reilly. (Churchill Livingstone; 5th edition, 2011).
Textbook
2.
Clinical Chemistry. http://clinchem.aaccjnls.org/
Periodicals.
Web site
Clinical Chemistry and Laboratory Medicine.
https://www.degruyter.com/view/j/cclm
Annals of Clinical Biochemistry.
https://journals.sagepub.com/toc/acb/current
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Endocrine system: overview a1 b1 c1
c2 ---
2. Thyroid gland and its disorders a2 b3
b5
c2
c3 ---
3. Male and female Reproductive system
and their disorders
a2
b3
b5
c2
c3 d3
4. Male and Female infertility; hormonal
profile and semen analysis + Quiz 1 a2
b3
b5
c2
c3 d3
5. Kidney diseases and Kidney function
tests a1, a3 b3
c2
c3 d2
6. Liver biochemical role; its disorders
and liver function tests a1, a3 b3 c3 d2
7. Anterior Pituitary gland and its
disorders a2 b5
c2
c3
d1
d3
9. Posterior Pituitary gland and its
disorders a2 b5
c2
c3
d1
d3
10. Clinical Enzymology a1, a4
b3 c1 d3
60 | P a g e
11. Tumor markers a1, a5
b4 c2 d1
12. Adrenal glands and its disorders a2
b1
b3
b5
c1
c2
c3
d1
d3
13. Complete blood counts and blood
indices
a1, a3
b1
b2 c1 d2
Name Signature
Course Coordinator: Dr. Samuel Tanas
Head of Department: Prof. Dr. Hassan El Kashif
Approval Date 6/2/2018
61 | P a g e
Other Courses Not Opened for Registration
at Academic Year (2017-2018)
Final Approval 2016-2017
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1. Basic Information:
Course title: Pharmacogenomics Course code: PB 523
Program on which the course is given: B. Pharm.
Department: Pharmacology & Biochemistry
Academic level: Faculty Elective course
Prerequisite: None
Credit hours: Lecture: 2 Practical: 0 Total: 2
2. Course Aims:
2.1. Understanding the drug efficacy and safety and the need to optimize these factors in
pharmacotherapy.
2.2. Identify how genetic variability influence the overall drug response.
2.3. Provide a detailed overview of the burgeoning field of genomic medicine and
pharmacogenomics.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A1 a1 Describe and define basic pharmacogenomics, concepts and taxonomy
A12
a2 Identify the basic principles and methods of diagnosis of pharmacogenomics and
pharmacogenetics.
a3 Evaluate polymorphism types and their impact on pharmacokinetics and
pharmacodynamics.
b. Intellectual Skills:
At the end of this course, student should be able to:
B7
b1 Determine the theories, application of DNA mutations and repair systems.
b2 Verify the role and implications of pharmacogenomics in discovery of new drugs
and treatment strategies.
b3 Explore the implications of the ethical, legal, social and economic issues related to
pharmacogenomic testing.
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C5
c1 Employ the safe and effective use of drugs on patients
c2 Decide the roles of pharmacogenomics and pharmacogenetics in health and
disease
d. General and Transferable Skills:
At the end of this course, student should be able to:
D2 d1. Obtain up-to-date resources for pharmacogenomic information.
D3 d2. Identify the problem affecting community with trial of solving by teamwork.
63 | P a g e
4. Contents:
4.1.Lectures:
Week
No. Topics
No. of
credit
hours
1. Introduction 2
2. History of pharmacogenomics 2
3. Genomics in human health & bioethics 2
4. Genetic basis of pharmacogenomics and pharmacogenetics 2
5. Genetic basis of pharmacogenomics and pharmacogenetics 2
6. Molecular techniques and diagnostics 2
7. Mid-Term exam ---
8. Pharmacogenetics of drug metabolism 2
9. Pharmacogenetics of drug metabolism 2
10. Pharmacogenomics and drug transport 2
11. Pharmacogenomics and drug transport 2
12. Pharmacodynamics and pharmacogenomics 2
13. Pharmacodynamics and pharmacogenomics 2
14. Final Exam
2 credit
hours 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Seminars
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam to assess knowledge, understanding, intellectual and professional skills
2. Class work to assess knowledge, understanding, intellectual skills, general skills and
confidence
6.2.Assessment schedule:
Assessment 1 Mid-term 7th week
Assessment 2 Quiz 10th week
Assessment 3 Written 14th &15th weeks
6.3.Weighing of Assessments:
Mid-Term Exam & course work 25 %
Final-Term Exam 75 %
Total 100%
64 | P a g e
7. List of References:
No. Reference type
1.
1.1. Pharmacogenomics and Personalized Medicine
(Methods in Pharmacology and Toxicology) by Nadine
Cohen 2008 edition
1.2. Pharmacogenomics: Applications to Patient Care,
ACCP
textbook
8. Matrix of course contents versus ILOs:
Study
week Course contents
ILOs
knowledge
and
understanding
intellectual
skills
professional
and
practical
skills
general and
transferable
skills
1 Introduction a1 b1,b3 c2 d1
2 History of pharmacogenomics a1 b1 -- --
3 Genomics in human health &
bioethics a1 b1,b3 c2 d1
4-5
Genetic Basis of
Pharmacogenomics and
pharmacogenetics
a1,a2 b1 c2 d1
6 Molecular Techniques and
Diagnostics a2, b2,b3 c1 d1
8-9 Pharmacogenetics of Drug
Metabolism a3 b2 c1 d2
10-11 Pharmacogenomics and Drug
Transport a3 b2 c1 d2
12-13 Pharmacodynamics and
Pharmacogenomics a3 b2,b3 c1 d2
Name Signature
Course Coordinator: Prof. Dr. Hassan A. Elkashef
Head of Department: Prof. Dr. Hassan A. Elkashef
Approval Date 12/2/2017
65 | P a g e
1. Basic Information:
Course title: Clinical toxicology Course code: PB 522
Program on which the course is given: B. Pharm.
Department: Pharmacology and Biochemistry
Academic level: Elective course
Prerequisite: None
Credit hours: Lecture: 2 Practical: Total: 2
2. Course Aims:
2.1 Learn the basics of forensic medicine that will enable the student to make medico-legal
judgment on simple cases of injuries.
2.2 Learn the basics of clinical toxicology that will enable the student to diagnose and manage
intoxicated patients.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A16
a1 Understand the general principles of poisoning management; explain actions,
interactions, uses and toxicity of certain medications.
a2 Understand toxic profile of various drugs and other xenobiotics including
sources, identification, symptoms, management, control and first aid measures.
A25 a3
Illustrate clinical features of diseases and appropriate medical intervention in
emergency situations, with stress on some genetic abnormalities and toxicology
of addiction and to define the principles of body function in health and disease
states; as well as the etiology, epidemiology, laboratory diagnosis, clinical aspects
of different diseases; and their pharmacotherapy
b. Intellectual Skills:
At the end of this course, student should be able to:
B11 b1
Assess drug-drug interactions, food drug interactions, adverse drug reactions and
predict possible incompatibilities and other prescription-related problems that
may occur during drug dispensing
B21
b2 Analyze, evaluate and interpret clinical cases of toxicity and estimate health
hazards concerning drug abuse, misuse and exposure to toxic agents.
b3
Differentiate between different toxic agents regarding their symptoms, as well as
their main lines of toxicity treatment and interpret clinical laboratory tests with
the impact of clinical symptoms.
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C7 c1 Undertake risk assessments concerning drug-drug interactions, adverse reactions,
toxicity profile and incompatibilities
C9 c2 Counsel patients when dispensing OTC and prescription drugs to ensure safe and
proper use of medicines.
C21 c3 Determine the toxicity profiles of different xenobiotics and chemotherapeutic
agents, detect poisons in biological specimens
66 | P a g e
d. General and Transferable Skills:
At the end of this course, student should be able to:
D1 d1 Communicate effectively with patients and health care professionals
D2 d2 Retrieve pharmaceutical, clinical and other drug information resources.
4. Contents:
4.1.Lectures:
Week
No. Topics
No. of
credit
hours
1. Basic principles of clinical toxicology 2
2. Management of an intoxicated patient 2
3. Household intoxication 2
4. Medical toxicology 2
5. Medical toxicology 2
6. Environmental Pollutants 2
7. Mid-term exam --
8. Substances of abuse 2
9. Drug dependence 2
10. Plant toxicity 2
11. Animal envenomation 2
12. Food-born intoxication 2
13. Revision 2
14. Final Exam
2 credit
hours 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Small group discussions (problem based learning)
5.3. Case study
6. Student Assessment Methods:
6.1.Assessment methods:
1. Mid-term to assess knowledge, understanding, intellectual skills, general skills
2. Quiz to assess knowledge, understanding, intellectual skills, general skills
3. Written exam to assess knowledge, understanding, intellectual and professional skills
6.2.Assessment schedule:
Assessment 1 Mid-term 7th week
Assessment 2 Quiz 10th week
Assessment 3 Written 14th &15th weeks
67 | P a g e
6.3.Weighing of Assessments:
Mid-Term Exam 15%
Quiz 10%
Final-Term Exam 75%
Total 100%
7. List of References:
No. Reference Type
1. Molecular, Clinical and Environmental Toxicology, 2009 Textbook
2.
Clinical Toxicology
http://toxnet.nlm.nih.gov
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
Website
8. Matrix of course contents versus ILOs:
Study
week Course contents
ILOs
knowledge
and
understanding
intellectual
skills
professional
and practical
skills
general and
transferable
skills
1 Basic principles of clinical
toxicology a1 -- c1, c2, c3 --
2 Management of an
intoxicated patient a1, a2, a3 b1, b3 c1, c2, c3 d1, d2
3 Household intoxication a1, a2, a3 b2, b3 c1 d1, d2
4-5 Medical toxicology a1, a2, a3 b1, b2, b3 c1, c2, c3 d1, d2
6 Environmental Pollutants a1, a2, a3 b1, b2, b3 c1, c2, c3 d2
8 Substances of abuse a1, a2, a3 b1, b2, b3 c1, c2, c3 d1, d2
9 Drug dependence a1, a2, a3 b1, b2, b3 c1, c2, c3 d1, d2
10 Plant toxicity a1, a2 b2 c1 d1, d2
11 Animal envenomation a1, a2 b2 c1 d1, d2
12 Food –born intoxication a1, a2, a3 b1, b2, b3 c1, c2, c3 d1, d2
13 Revision
Name Signature
Course Coordinator: Prof. Dr. Hassan El-Kashef
Head of Department: Prof. Dr. Hassan El-Kashef
Approval Date 12/2/2017
68 | P a g e
1. Basic Information:
Course title: Veterinary pharmacy Course code: PB 536
Program on which the course is given: B. Pharm.
Department: Pharmacology & Biochemistry
Academic level: Faculty Elective course
Prerequisite: None
Credit hours: Lecture: 2 Practical: 0 Total: 2
2. Course Aims:
1. List common adverse drug interactions in veterinary patients
2. Explain current trends in veterinary prescribing and compounding.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A2 a1
Recognize the physico-chemical properties of drugs and various substances used
in preparation of medicines, in addition to the properties of different
pharmaceutical dosage forms.
A6 a2 Describe properties of different pharmaceutical dosage forms and drug delivery
systems.
A16 a3 Recognize the toxic profile of various drugs and other xenobiotics; including
identification, symptoms, control and first aid measures.
b. Intellectual Skills:
At the end of this course, student should be able to:
B1 b1 Design process of formulation of safe and effective medicines and dealing with
new drug delivery systems.
B9 b2 Select the proper drugs for various disease conditions using the
pharmacotherapeutic principles.
B15 b3 Estimate health hazards concerning exposure to toxic agents.
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C13 c1 Assess risks concerning drug interactions, adverse reaction and incompatibilities
in different pharmaceutical preparations.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D11 d1 Generate effective and reasonable solutions for rising problems based on the
available information.
69 | P a g e
4. Contents:
4.1.Lectures:
Week
No. Topics
No. of
credit
hours
1. Veterinary Prescribing 2
2. Compounding Concerns 2
3. Dispensing Concerns 2
4. Important Drug Interactions: NSAIDS 2
5. Important Drug Interactions: NSAIDS 2
6. Other Veterinary curiosities (as paracetamol) 2
7. Mid-Term exam --
8. Toxicity Of Human Medication For Pets 2
9. Insulin Dosing In Veterinary Species 2
10. Treatment of common disease (infection) 2
11. Treatment of common disease (infection) 2
12. Treatment of common disease (musculoskeletal) 2
13. Treatment of common disease (neurological) 2
14. Final Exam
2 credit
hours 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Case study
6. Student Assessment Methods:
6.1.Assessment methods:
1. Written exam to assess knowledge, understanding, intellectual and professional skills
2. Class work to assess knowledge, understanding, intellectual skills, general skills and
confidence
3. Quizzes to assess knowledge, understanding and intellectual skills
4. Case study to assess the skills of problem-solving and data presentation
6.2.Assessment schedule:
Assessment 1 Mid-term 7th week
Assessment 2 Quiz 10th week
Assessment 3 Written 14th &15th weeks
6.3.Weighing of Assessments:
Mid-Term Exam & course work 25%
Final-Term Exam 75%
Total 100%
70 | P a g e
7. List of References:
No. Reference type
1. Veterinary pharmacy by Steven B. Kayne and Michael H.
Jopson 2005 textbook
8. Matrix of course contents versus ILOs:
Study
week Course contents
ILOs
knowledge
and
understanding
intellectual
skills
professional
and
practical
skills
general and
transferable
skills
1. Veterinary Prescribing a1, a2 b1, c1 --
2. Compounding Concerns a1, a2 b1, c1 --
3. Dispensing Concerns a1, a2 b1, c1 --
4. Important Drug Interactions
NSAIDs a1,a3 b3 c1 d1
5. Important Drug Interactions
NSAIDs a1,a3 b3 c1 d1
6. Other Veterinary Curiosities a1,a3 b2 c1 d1
8 Toxicity of Human
Medication For Pets a3 b3 c1 d1
9 Insulin Dosing In Veterinary
Species a1 b2 c1 d1
10-13 Treatment of common
diseases a3 b2, b3 c1 d1
Name Signature
Course Coordinator: Prof. Dr. Hassan A. Elkashef
Head of Department: Prof. Dr. Hassan A. Elkashef
Approval Date 12/2/2017