2002 alkaloids

alkaloidsU 0600

23 - 216Synthesis of the Potent Antitumoral Marine Alkaloid Variolin B.— Key-step in the synthesis of variolin B (XII) is the formation of the an-nulated 2-aminopyrimidine (III) by tandem aza-Wittig/carbodiimide-mediatedcyclization. — (MOLINA, PEDRO; FRESNEDA, PILAR M.; DELGADO,SANTIAGO; BLEDA, JUAN ANTONIO; Tetrahedron Lett. 43 (2002) 6, 1005-1007; Dep. Quim. Org., Fac. Quim., Univ. Murcia, E-30071 Murcia, Spain; EN)

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