CarbohydratesU 0500 DOI: 10.1002/chin.201241201

Convenient One-Pot Synthesis of Thiosugars and Their Efficient Conversion to Polyoxygenated Cycloalkenes. — A one-pot protocol for the synthesis of thiosugars with xylo, ribo, gluco, manno, fuco, and galacto configuration via thioetherification of diols with sodium sulfide is developed. These products can be converted to optically pure cycloalkenes as carbohydrate mimetics. — (ZHANG, J.; NIU, Y.; CAO, X.; YE*, X.-S.; Tetrahedron 68 (2012) 22, 4242-4247, http://dx.doi.org/10.1016/j.tet.2012.03.086 ; State Key Lab. Nat. Biomimetic Drugs, Sch. Pharm. Sci., Peking Univ., Beijing 100191, Peop. Rep. China; Eng.) — Bartels

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ChemInform 2012, 43, issue 41 © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim