1997 indan derivatives

indan derivativesQ 1050

45 - 107Asymmetric Synthesis of (+)-(3aS,4S,7aS)-3a-Hydroxy-4,7a-dimethylperhydroindane-1,5-dione. — Piperidine, added in smallamounts (piperidine: proline = 0.25:1) to the reaction mixture, increases therate of cyclization and leads to an optimized synthesis of the title compound(II) in less than 2 days. — (MEDARDE, M.; CABELLERO, E.; MELERO,C. P.; TOME, F.; SAN FELICIANO, A.; Tetrahedron: Asymmetry 8 (1997)13, 2075-2077; Dep. Quim. Org. Farm., Fac. Farm., Univ. Salamanca, E-37007Salamanca, Spain; EN)

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