2002 fused pyridine derivatives

fused pyridine derivativesR 0450

49 - 137A New Approach to the Synthesis of 2-Aminoimidazo[1,2-a]pyridineDerivatives Through Rapid Parallel Synthesis. — The title com-pounds, e.g. (IV), are prepared by one-pot reaction of pyridines (I) withcyanamide (II) and bromides (III). Best condition for the reaction with (II)is the use of tBu-OK in DMSO. — (JARAMILLO, CARLOS; DE DIEGO,J. EUGENIO; HAMDOUCHI, CHAFIQ; Synlett (2002) 9, 1544-1546; Cent.Invest. Lilly S. A., E-28108 Alcobendas, Madrid, Spain; EN)

1