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Benign Metastasizing Leiomyoma
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• Female 58 years old• Latin teacher in a French University• Past history: 2003 hysterectomy for uterine
leiomyomas-----------------------------------------------------• October 2010: abdominal pain• CT scan
2013 09637 NK
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October 20102013 09637 NK
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• Percutaneous biopsy in a Cancer Center: Leiomyomatosis
• Hormonal receptors +
2013 09637 NK
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• Double J catheter• Aromatase inhibitor• Treatment stopped by the patient in march 2013
because of its intolerance and worsening functional signs
2013 09637 NK
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Sept 2013(+ 3 years)
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Surgery
• November 2013
• Partial cystectomy: Enterocystoplasty• Rectal resection (colo rectal anastomosis)• Resection of the left external iliac vein• Resection of part of vagina
• Resection of the nodule in the right iliac fossa2013 09637 NK
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Pathology• Main mass: 29 X 20 X16, cystic• Spindle-shaped smooth muscle cells• 0 mitosis /10 HPF• Necrosis < 50%• KI 67: 1%• Vagina and bladder infiltrated• No intra luminal tumor in the left
external iliac vein• Benign Metastasizing Leiomyoma• 1 Nodule 8 X 5 cm: idem
2013 09637 NK Desmin
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Sept 2014AsymptomaticNo treatment