Supplementary file:

Cocoa diet modulates gut microbiota composition and improves

intestinal health in Zucker diabetic rats

David Álvarez-Cilleros1, Sonia Ramos1, María Elvira López-Oliva2, Fernando Escrivá3,4,

Carmen Álvarez3,4, Elisa Fernández-Millán3,4*, María Ángeles Martín1,4*

Legend to Supplementary Figure 1.-

Figure 1.- Effects of cocoa diet on cyclin E and p21 of Zucker lean (ZL), Zucker

Diabetic rats fed control diet (ZDF-C) and Zucker Diabetic rats fed cocoa diet (ZDF-

Co). Representative immunohistochemistry stained of Cyclin E (A) and p21 (B)

(brown-stained) in distal colon and inmunoreactive score (scale bar 10 µm). Values are

expressed as mean ± SD (n = 6-8).

Supplementary Figure 1.-