Download - Animal/Dairy Science 434
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Animal/Dairy Science 434 Lec 2:
Female comparative anatomy;
History of Reproductive Physiology
Kangaroo Rat Human
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Ovarian Differences
Cow Mare
Sow
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• Inversion of the cortex and medulla.
• Ovulation occurs at the Ovulation Fossa
Cow SowCow, Sow, Ewe, Human
• Cortex on outside• Ovulation can occur on
any point of the ovary
Mare
MareBlood vesselsand connectivetissue in medulla
Preovulatory TertiaryFollicle
Internal CL
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Cow
Sow
Mare
Uterine and Cervical Differences
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DuplexOposum Rabbit, Mouse
2 Cervixes
2 Uterine Horns
2 Vaginas
1 Vagina
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Bicornuate
Ewe
Cow
Sow
1 Vagina1 Cervix1 Uterine Body2 Uterine Horns
Smaller uterine horns
Large uterine horns
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Bicornuate
1 Vagina1 Cervix1 Uterine Body 2 Uterine Horns
Large uterine bodySmaller uterine horns
Mare
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Bicornuate
1 Vagina1 Cervix1 Uterine Body 2 Uterine Horns
Dog
Cat
Small uterine bodyLong uterine horns
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SimplexWoman
1 Vagina1 Cervix1 Uterine Body
Large uterine bodyNo uterine horns
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Human Tract
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Human Tract
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A 47-year old woman underwent a hysterectomy for excessively heavy menses. She had previously had four normal deliveries. This structure was removed, what is wrong?
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Cervix
•Cervix is composed of thick connective tissue
COW
Cow has 4-5annular rings
Uterine Body
Vagina
External Cervical Os
Internal Cervical Os
• Mucus is secreted near the time of breeding and ovulation.
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Noobstacles
Interdigitatingpads
Nofornix vagina
Mare SowUterine Body Uterine Body
Vagina
Fornix Vagina
LongitudinalFolds
Vagina
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Cervix
CervicalRing
CervicalRing
CervicalRing
CervicalRing
FornixFornix
FornixFornix
FornixFornix
Anterior Vagina Anterior Vagina
COW
EWEExternal OsExternal Os
Internal OsInternal Os
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Cervix
Sow Mare
CervicalFolds
CervicalFolds
IPIP
FVFV
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External GenitaliaMareMare CowCow SowSow
EweEwe
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What is this?What is this?
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Human Tract
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External Genitalia
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Vagina Anterior Vagina Posterior Vagina (Vestibule)
ColumnarEpithelium
StratifiedSquamousEpithelium
Submucosa
Urethra
Submucosa
Mucosa
FornixFornix Vulva-Vaginal
Sphincter(Hymen)
Vulva-Vaginal
Sphincter(Hymen)
Cervix
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Infundibulum Ovary
Oviduct
Uterus
cloaca
vagina
Left side of Reproductive Tract Develops!!Left side of Reproductive Tract Develops!!
Magnum
Isthmus
Shell Gland
Avian Female
Anatomy albumen
shell membrane
cleaving blastodisc
shell
RightOviduc
t
Intestine
chalazae
perivitellinemembrane
24 hrs50K cells24 hrs50K cells
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Chicken TractChicken TractOvary
Magnum
Shell GlandIntestine
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Chicken OvaryHierarchalFollicles
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Ovary with large follicles
removed
Ruptured follicle
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Chicken Reproductive Tract
Follicles
Infundibulum
Magnum
Isthmus
Shell Gland
Cloaca
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Infundibulum
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Cloaca
Vagina
Vaginal opening
Intestine
opening
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Cloaca of Chicken
Vagina opening
Intestine
opening
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Historical Development of Reproductive PhysiologyHistorical Development of Reproductive Physiology
Aristotle 384-322 BCAristotle 384-322 BC
Generation of Animals
• Fetus arises from menstrual blood
• Seminal plasma initiates the conversion of menstrual blood
• Semen from all parts of body
• Fetus arises from menstrual blood
• Seminal plasma initiates the conversion of menstrual blood
• Semen from all parts of body
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The Age of Gross AnatomyThe Age of Gross Anatomy
• Fallopius (1562) – Describes the oviduct
• Coiter (1573)– Describes the corpus luteum
• Regnier de Graff (1672)– Describes the antral follicle (Graafian Follicle)
• Fallopius (1562) – Describes the oviduct
• Coiter (1573)– Describes the corpus luteum
• Regnier de Graff (1672)– Describes the antral follicle (Graafian Follicle)
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Development of the MicroscopeDevelopment of the Microscope• van Leewenhoek
(1677)– Describes spermatozoa
in semen
• van Leewenhoek (1677)– Describes spermatozoa
in semen
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What is the role of spermatozoa?What is the role of spermatozoa?
• Spallanzani (1780)– Sperm were the fertilizing agent in semen– Successful artificial insemination of a dog
• Dumas (1825)– Proves sperm the fertilizing agent
• Spallanzani (1780)– Sperm were the fertilizing agent in semen– Successful artificial insemination of a dog
• Dumas (1825)– Proves sperm the fertilizing agent
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Modern Reprod. PhysiologyModern Reprod. Physiology
• Gonads produce steroid hormones
• Regulation of estrous cycles in females
• Radioimmunoassay (RIA)
• Artificial Insemination
• Cryopreservation
• Prostaglandin used to control estrous cycles
• Biotechnology
• Gonads produce steroid hormones
• Regulation of estrous cycles in females
• Radioimmunoassay (RIA)
• Artificial Insemination
• Cryopreservation
• Prostaglandin used to control estrous cycles
• Biotechnology
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Approach to ApplicationsApproach to Applications
• Develop basic knowledge of how system works
• Investigate methods that can perturb the system
• Manipulate the system to improve reproduction– Estrus Synchronization
• Develop basic knowledge of how system works
• Investigate methods that can perturb the system
• Manipulate the system to improve reproduction– Estrus Synchronization
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Enhancing ReproductionEnhancing Reproduction
• Small improvements have profound effects on production– 3% improvement in birth rate results in an
additional:• 1 million beef calves/year• 3.2 million pigs/year• 3.7 million gallons of milk/year
• Small improvements have profound effects on production– 3% improvement in birth rate results in an
additional:• 1 million beef calves/year• 3.2 million pigs/year• 3.7 million gallons of milk/year
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Current TrendsCurrent Trends
ProductionProduction ReproductionReproductionMetabolic
andPhysiologic
Changes
• Continuing need to:– improve reproductive performance– understand how to apply new technology
• Ovsynch
• Clonning
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Limiting ReproductionLimiting Reproduction
HumansHumans
PetsPets
InsectsInsects
WildlifeWildlife