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Page 1: Adaptation: The Body’s Response to Trauma by Brohi

ADAPTATION: THE BODY’SRESPONSE TO TRAUMA

Centre for Trauma SciencesQueen Mary University of Londonwww.c4ts.qmul.ac.uk

Royal London Major Trauma CentreBarts Health NHS Trust

KARIM BROHI, FRCS FRCAProfessor of Trauma Sciences, QMUL

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EXSANGUINATION

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CATASTROPHIC ORGAN DYSFUNCTION

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INFECTION

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PERSISTENT INFLAMMATION CATABOLISM SYNDROME

(PICS)

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SURVIVAL PATHWAYS

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NFκB

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NFκB

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NFκB

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STOP THE DRIVERS OF INFLAMMATION

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DON’T FIGHTEVOLUTION

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