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A CENTRIFUGATION-ENHANCED HIGH-EFFICIENCY MICRO-FILTERWITH SPIRAL CHANNEL
Xu Ji, Wei Wang, Xia Lou, Jianhong Peng, and Zhihong LiNational Key Laboratory of Micro/Nano Fabrication Technology
Institute of Microelectronics, Peking University, Beijing, 100871, China
(Transducers 2007 P.1865~1868)
Reporter: Chung-Kuang Chin ( 秦重光 )
Date:1/2/2008
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Outline
Introduction Principle & Numerical Simulations Fabrication Experiments Results & Discussion
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Introduction
Micro-filters/Separators- Goal : to separate, remove and pre-concentrate particles from original mixtures .- usually employed prior to analysis in biologic and chemical diagnostic processes.- Classification : Active or Passive
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Introduction (cont.)
Active micro-filters/Separators-運用靜電力、磁力、機械力 、介電泳力 (DEP) 、光鑷夾 ( 光場 )等來完成。
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Introduction (cont.)
Passive micro-filters/Separators-純粹靠結構設計來過濾或分類。
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Principle
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Numerical Simulations
flux, which penetrates through the filtration wall, in a circle channel device is 2.25 times than that in thestraight channel filter at the same conditions.
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Fabrication
Width:120μm
Pores:3.5μm
Depth:60μm
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Experiments
7.2μL/S 60μL/S
7.2μL/S -> 1.2 : 1(number ratio of 大 :小 )60μL/S -> 1.6 : 1(number ratio of 大 :小 )
6.5:1
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Results & Discussion
Ref: Separation of Blood in Microchannel Bends, C. Blattert¹, R. Jurischka¹,I. Tahhan¹, A. Schoth¹, P. Kerth², W. Menz¹ 1 Institut fuer Mikrosystemtechnik, Universitaet Freiburg, Germany 2PREVENTOR µTBC GmbH, Pfungstadt, Germany, IEEE 2003
1. Higher flow velocity allows higher filtration efficiency.
2. Large particles are remarkably enriched by several filtration circles.
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Reference Review: Microfluidics technology for manipulation and analysis of biol
ogical cells, Changqing Yi, Cheuk-Wing Li, Shenglin Ji, Mengsu Yang, Analytica Chimica Acta, 2006
Separation of Blood in Microchannel Bends, C. Blattert¹, R. Jurischka¹,I. Tahhan¹, A. Schoth¹, P. Kerth², W. Menz¹ 1 Institut fuer Mikrosystemtechnik, Universitaet Freiburg, Germany 2PREVENTOR µTBC GmbH, Pfungstadt, Germany, IEEE 2003
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THE END
Thanks for Your Attention!