2015 Hopkins C.A.R.E.S Summer Symposium
July 30, 2015
Armstrong Medical Education Building
10:00-3:30 p.m.
Career Academic and Research Experiences for Students
Schedule
10:00- 11:00a.m. Welcome AMEB, 1st Floor Auditorium
Keynote Speaker Peter Agre, M.D.
Background Stories Branecia Bull, MERIT
Makayla Nicole Proctor, MCHC/RISE-UP
Andres Cordoba, Centro Sol Nadeen Ibrahim, SURE Kelcee Everette, INBT
11:00a.m. - 12:00p.m. Poster Session 1
AMEB, 2nd Floor Lobby
12:00p.m.
12:30p.m.-2:00p.m.
Lunch AMEB, 1st Floor Lobby
Oral Presentations
AMEB, 1st Floor Auditoriums (East and West)
2:00-3:00p.m. Poster Session 2
AMEB, 2nd Floor Lobby
3:00- 3:30p.m. Closing
AMEB, 1st Floor Auditorium
Outstanding Students Awards
Reception AMEB, 1st Floor Lobby
Keynote Speaker
Peter Agre, M.D.
Nobel laureate Peter Agre, MD became the second director of the Johns Hopkins Malaria Research Institute in January, 2008, succeeding founding director Diane E. Griffin, MD, PhD, who remains as chair of the department of Molecular Microbiology and Immunology.
Dr. Agre received his BA in chemistry from Augsburg College in 1970, and his MD from Johns Hopkins in 1974. Following an Internal Medicine Residency at Case Western Reserve University Hospitals of Cleveland and a Hematology-Oncology Fellowship at the University of North Carolina at Chapel Hill, Dr. Agre returned to Johns Hopkins as a postdoctoral fellow in cell biology. Dr. Agre joined the faculty in 1984 and has spent most of his professional life at Hopkins' School of Medicine, leaving in 2005 to go to become Vice Chancellor for Science and Technology at Duke University Medical Center. His return to Hopkins and JHMRI in 2008 gives Dr. Agre the opportunity to concentrate on an area in which he has always been interested - the problem of disease in the developing world.
Dr. Agre's research in red-blood-cell biochemistry led to the first known membrane defects in congenital hemolytic anemias (spherocytosis) and produced the first isolation of the Rh blood group antigens. In 1992, his laboratory became widely recognized for discovering the aquaporins, a family of water channel proteins found throughout nature and responsible for numerous physiological processes in humans— including kidney concentration, as well as secretion of spinal fluid, aqueous humor, tears, sweat, and release of glycerol from fat. Aquaporins have been implicated in multiple clinical disorders—including fluid retention, bedwetting, brain edema, cataracts, heat prostration, and obesity. Water transport in lower organisms, microbes, and plants also depend upon aquaporins. For this work, Dr. Agre shared the 2003 Nobel Prize in Chemistry with Roderick MacKinnon of Rockefeller University.
Not long after receiving the Nobel Prize, Dr. Agre was awarded a JHMRI pilot grant to extend his studies of aquaporins to malaria, addressing the question of whether or not aquaporins could be exploited as a means of treating or preventing the disease. Initial encouraging results have led to an NIH grant and a focus on malaria as the primary area of study in Dr. Agre's laboratory.
As President of the American Association for the Advancement of Science, Dr. Agre led science in diplomacy missions to Cuba, North Korea and Myanmar Burma. His honors include election to the National Academy of Sciences in 2000, the Institute of Medicine in 2005, the American
Academy of Arts and Sciences in 2003, and the American Philosophical Society in 2004. He has also received honorary doctorates from universities in Denmark, Japan, Norway, Greece, Mexico, Hungary, Poland and the United States.
2015 Hopkins C.A.R.E.S. Summer Programs
Biophysics Research for Baltimore Teens: Biophysics for Baltimore Teens (BRBT) is a new initiative, which will give Baltimore city teens a chance to do basic biomedical research in Johns Hopkins biophysics labs on both the Homewood and JHMI campuses. BRBT is offered through the Johns Hopkins Program in Molecular Biophysics (PMB) and PMB graduate students on both campuses will mentor BRBT interns. The interns’ exposure to laboratory research will be augmented with a weekly course in basic laboratory skills taught by graduate students and overseen by PMB faculty. CTY Center Scholars Program: The Center Scholars Program, developed by the Center for Talented Youth and Dr. Andrew Feinberg's Center for Excellence in Genome Science (CEGS) is designed to encourage academically advanced, historically under-represented minority high school students to explore careers in scientific research, particularly the field of genomics. CTY Summer Research Program: This program, sponsored by the Simons Foundation, invites high achieving, academically advanced high school students to participate in a residential research experiences across disciplines at both the Johns Hopkins University and School of Medicine. This six week residential program pairs students with research mentors through a highly selective process which considers both student and mentor skills and interests. Students attend career and research seminars and participate in a journal club sponsored by each host lab. Center for Computational Biology Summer Internship Program: The CCB internship program (http://ccb.jhu.edu/internship.shtml) will provide you with hands-on research experience as part of ongoing research projects with bioinformatics and genomics faculty in the Departments of Biomedical Engineering, Computer Science, Biostatistics, and Biology, and in the Institute of Genetic Medicine. Current areas of research include analysis of high-throughput DNA sequence data to characterize genes and their variations, studies of the microbiome, assembly of whole-genome shotgun data from various species, and the development of new computational and statistical methods for other genome analysis problems. The program involves full-time research for 8-12 weeks between May and August. Note that in 2015, for the first time, the CCB Summer Internships are being organized jointly with the Summer Research Expeditions in the Computer Science Department at JHU. The program is open to college undergraduates and to exceptional high school students. Centro SOL Programa de Verano para Jovenes: Summer program for Spanish/English bilingual high school students in Baltimore City. The program’s goal is to expose bilingual high school students to the medical field by offering meaningful opportunities to work with JHU School of Medicine faculty in clinical settings that serve Latino patients with limited-English proficiency. Patients with limited English proficiency (LEP) frequently have difficulties navigating the healthcare system, explaining their
illness, understanding their providers’ recommendations, and participating fully in the development of a treatment plan. In this project, we want to capitalize on the strength of bilingual youth in our community. Students who are fluent in both Spanish and English will be invited to apply to the program. Following orientation, students will be placed in various clinical settings, where they can utilize their Spanish language skills to assist Latino patients with limited-English proficiency in various scenarios, such as registering for care, guiding them to various places in the hospital, greeting them and providing information at the entrance or information desks throughout Bayview Hospital. In addition, students will shadow Johns Hopkins Hospital Spanish language interpreters for a day a week. This experience will allow them to appreciate the importance of professional medical interpretation during clinical encounters and give them an opportunity to pursue further training in this area if they are interested. Students will meet weekly with faculty preceptors to reflect on their experiences and provide feedback to our program. We see bilingual youth as a unique resource with enormous potential to succeed in STEM (Science, Technology, Engineering, and Math) careers under the right guidance. Through this pilot program, we will expose motivated Baltimore youth to careers in medicine, mentor them at a leading medical institution, and empower them to pursue further training that capitalizes on their Spanish language skills, while improving services to our Latino patients. Diversity and Academic Advancement Summer Institute (DAASI): The Diversity and Academic Advancement Summer Institute (DAASI) is a partnership between Johns Hopkins School of Medicine Office for Student Diversity and Thread (formerly Incentive Mentoring Program). The goals are to three fold: (1) Academic Assistance: Provide a comprehensive, engaging curriculum to bolster participants’ academic self-confidence and capabilities; (2) Service, Life Skills, and Team Work: Create opportunities for participants to learn important life and professional skills through work opportunities and service learning experiences; and (3) Visualizing Success: Expose them to science and health educational pathways so that they may visualize the possibility of pursuing careers in science. Institute for NanoBiotechnology Research Experience for Undergraduates (INBT): The Institute for NanoBiotechnology at Johns Hopkins University offers undergraduate students from colleges and universities around the country a chance to participate in research projects in the exciting and rapidly growing area of Nanobiotechnology, a place where biology, medicine, and nanotech meet. For more information, visit http://inbt.jhu.edu/education/undergraduate/reu/. The Johns Hopkins Internship in Brain Science Program (JHIBS): Project Pipeline Baltimore: The long-term goal of the JHIBS program is to significantly increase the pool of qualified under-represented professional candidates from Baltimore in the neurosciences and mental health medicine through an eight-week summer research and enrichment experience that targets high school juniors and seniors. The program will provide the necessary exposure, knowledge, and career-long mentoring, to help propel students toward a trajectory as a STEM professional. The program has been in existence for seven years funded by the Cohen Foundation and jointly this year with a grant from the National Institutes of Mental Health.
Maternal Child Health Careers/Research Initiatives for Student Enhancement Undergraduate Program (MCHC/RISEUP) at Kennedy Krieger Institute: The MCHC/RISE-UP is a 10-week summer public health leadership program designed for undergraduates in their junior and senior year and recent baccalaureate degree students (within 12 months of the MCHC/RISE-UP orientation) who are interested in learning more about preventing health disparities and promoting health equity and have a cumulative GPA of at least 2.5 on a 4-point scale. MCHC/RISE-UP is a national consortium of institutions including the Kennedy Krieger Institute (KKI; lead institution), Maryland Center for Developmental Disabilities, Johns Hopkins University School of Medicine, Nursing, and Public Health, University of Southern California, California State University-LA, and University of South Dakota Sanford School of Medicine Center for Disabilities. Three public health leadership tracks are offered: (1) clinical (KKI only), (2) research, and (3) community engagement and advocacy.
Medical Education Initiative for Teens (MERIT):
The Medical Education Resources Initiative for Teens (MERIT) aims to eliminate health care
disparities by transforming underrepresented high school students into health care leaders. To
accomplish these goals, MERIT provides seven years of academic, professional, and social
support. Scholars are selected during their sophomore year of high school and participate in
intensive MERIT programming until graduation including weekly Saturday sessions focused
on academic enrichment and college admissions guidance, paid summer internships in hospitals
and laboratories, and longitudinal mentoring. After high school, they become MERIT alumni
and receive continued guidance throughout college. Health care disparities will only be
eliminated if the workforce mirrors the communities we serve. MERIT Scholars’ voices are not
represented now, but one day, they will be poised to influence critical decisions. Psychiatry Summer Training and Research Program (P-STAR): The Psychiatry Summer Training and Research (P-STAR) program offers undergraduates interested in Behavioral and Biological Sciences the opportunity to work for ten weeks under the guidance of a faculty member at Johns Hopkins Medicine. Through one-on-one work with a faculty mentor, students gain hands-on experience in academic research and clinical environments. To provide in-depth exposure to Translational Psychiatry, especially that on schizophrenia and related disorders, we will have students work in both a laboratory setting and in clinical rotations. Pulmonary and Critical Care Medicine Summer Internship Program: The Division of Pulmonary and Critical Care Medicine hosts undergraduate students each summer as part of an NIH-funded program to enhance diversity in biomedical sciences. Students from around the United States and Puerto Rico join faculty for a ten-week, research-focused experience that extends from Memorial Day weekend through the first week of August. Students are matched with mentors based on their interests. Students work on specific research projects under the supervision of their mentor. Projects span a broad range of research, from the basic science of endothelial or epithelial cell biology to asthma epidemiology. In addition to the research experience, students participate in a weekly journal club, during which they present primary research articles to their peers and members of the faculty. Students also attend a seminar series featuring faculty members from Johns Hopkins and the NIH. This forum provides students with the opportunity to interact with faculty members and hear
different perspectives on issues related to career development. Students interested in clinical medicine are given the opportunity to “round” with the Johns Hopkins Medicine residents, providing a glimpse of life in clinical medicine as a resident at an academic institution. Stanley Summer Scholars Program: The goal of the Stanley Summer Scholars Program of the Stanley Division of Developmental Neurovirology, Dept. Pediatrics, is to foster enthusiasm for the study of the etiology, pathology, immunology, prevention and treatment of serious psychiatric diseases such as schizophrenia and bipolar disorder. By offering students the opportunity to gain laboratory experience while working closely with a mentor from the Stanley Division, we hope to encourage the pursuit of careers in basic, translational or clinical research focusing on major mental illnesses. Research performed in the Stanley Division is interdisciplinary and projects are available in a number of fields including molecular biology, immunology, virology, parasitology, cell culture, animal behavior and neuroscience. Summer Academic Research Experience (SARE): SARE is an 8-week outreach program that seeks to develop exceptional high school students from the greater Baltimore area by introducing them to academic research with a secondary emphasis on STEM and health-related professions. We provide our scholars with a unique exposure to modern scientific research, combined with additional tutoring to fortify basic academic skills. Students spend 70% of the time working in research labs and 30% of the time working on academic skills, including science, writing, and mathematics. This is a paid
internship and we request that ⅔ of the stipend be set aside for college. Summer Internship Program Basic Science Institute: The Summer Internship Program (SIP) provides experience in research laboratories to
students of diverse backgrounds, including underrepresented minority students, students from
economically disadvantaged and underserved backgrounds and students with disabilities that
have completed one - two or more years of college. The purpose of this exposure to biomedical
and/or public health research is to encourage students to consider careers in science, medicine
and public health.
Summer Urological Research Experience (SURE) at the Brady Urological Institute: As one of the leading urology departments in the world, the Brady Urological Institute plays a
key role in the advancement in the understanding and treatment of urological diseases and
cancer. As a part of the Department of Urology, the SURE Program is uniquely positioned to
allow students to experience a research opportunity that will allow them to understand how
advances at the bench can be translated to the bedside and how knowledge that can be gained
from treating patients can then be translated back to the bench. Research that occurs within
the department draws from a diverse list of expertise to elucidate answers for the current
paradigms in urologic oncology and other urologic diseases: cell biology, biochemistry,
molecular biology, oncology, biomedical engineering, genetics, cellular and molecular medicine,
and sexual dysfunction. During the 10 week program, students will conduct research related
to the overall goal of their mentoring laboratory while attending a series of seminars and
professional development workshops developed to provide the students with knowledge and
skills that will prepare them for post graduate education (MD, PhD, or similar) and a career in
biomedical research. Housed in a department in which the clinical operations are closely tied to
the ongoing research, students of the SURE Program are also offered an opportunity to view
live surgical procedures and shadow clinicians to obtain a better understanding of how the field
of urological medicine is practiced today. In a Department that utilizes a multidisciplinary
approach to its research missions, the SURE Program is able to provide research opportunities
in the areas of Cell biology, Biochemistry, Molecular biology, Oncology, Biomarker
development, Biomedical engineering, Genetics, Immunology, Pharmacology and molecular
sciences, Cellular and molecular medicine, and Sexual dysfunction. Additional information
about the SURE Program can be obtained by viewing the program
Oral Presentations
12:30p.m.-1:45p.m.
East Auditorium
West Auditorium
Time Name of Student Program Title 12:30pm Jennifer Mendez Centro SOL MIC & MBC Tuberculosis
Experiment
12:50pm Assefa Akinwole SARE Probing for Conformation Changes of DXP Synthase in the Presence of
Analogs 1:10pm Rosaura Garcia MCHC/RISE-UP Using a Template to Develop
Focused Health Education Communication
Time Name of Student Program Title 12:30pm Rachael Avidor and
Kayla McDaniel MERIT Increasing Awareness of Thyroid
Cancer in Women 12:50pm Chikaodi Nwanegwo BRBT IFI16 and autoimmunity
1:10pm Joseph Paggi CCB Graph-based alignment of DNA
sequence to a population of genomes 1:20pm Ashley Williams INBT Microfluidic devices to study effects
of varying levels of sheer stress on the proliferation and morphology of endothelial cells and derived brain
stem cells 1:40pm Thomas Valente SURE Visualization of androgen receptor
transcripts encoding discrete functional domains
1:20pm Christopher DaSilva PCCM Impact of environmental pollutants in a cohort of patients that have been diagnosed with chronic obstructive
pulmonary disease (COPD)
1:40pm Paige Greenwood SIP HIV/HCV coinfection leads to elevated expression of
proinflammatory cytokines compared to monoinfection
Poster Presentations
Session 1 (11:00-12:00)
# Name Program Title 1 BRBT BRBT Bootcamp
2 Chikaodi Nwanegwo
BRBT IFI16 and Autoimmunity
3 Shreya Bhatia CCB Meta-Analysis of miRNA Regulation, Abundance, and Target Genes in Brains of
Alzheimer’s Patients
4 Farhan Damani CCB "A Bayesian Network Approach to Identifying Functional Rare Variants"
5 Emily Herring Alison Samsel
CCB “Metagenomics classification with untranslated versus translated search”
6 Kevin Huang CCB "Improved Microbial Gene Finding Using Large Protein Sequence Data Sets"
7 Emma Jin CCB “Clustering of repetitive genomic sequences”
8 Nishika Karbhari Robert Phillips
CCB "SRA Trait Prediction using Genomic Data"
9 Jennifer Mendez Centro SOL MIC & MBC Tuberculosis Experiment
10 Caleb Akers INBT Cytotoxic Effect of Hyperthermia on Breast Cancer Cells
11 Kurt Castro INBT Multiplexed Color-coded Detection of Sexually Transmitted Diseases Based on Rolling Circle
Amplification
12 Alex Chavez INBT A microfluidic vessel for measuring intracellular uptake of cell-penetrating peptides
13 Nicolas Deshler INBT Biomechanics and Aerodynamics of Cricket Jumps
14 Alyssa Ertel INBT Self-Assembling Bioelectronic Materials
15 Franklyn Hall INBT Determination of the Optimal Oxygen Saturation for ECFC Network Formation Using
Layered Hydrogels
16 Athenia Jones INBT Observing the Effects of Substrate Stiffness on Brain Endothelial Cell Behavior
17 Briana Davis JHIBS Oxytocin and Vasopressin: Parallel Processing in the Social Brain
18 Rochinelle Dongmo
JHIBS Identification of HIV-infected Tissue Macrophages in Humanized Mice Part I
19 Osama Hassan JHIBS How does BACE1 inhibitor effect APP abundance in diabetic mice
20 Brittany Jones JHIBS NORT: Novel Object Recognition Test to Study Short-term Memory
21 Sabreenah Khan JHIBS The Don Project
22 Kayla Hall JHIBS Identification of HIV-infected Tissue Macrophages in Humanized Mice Part II
23 Brandon Addison MCHC/RISE-UP Kennedy Krieger Institute Behavioral Management Program
24 Mariah Barber Olivia Dure
MCHC/RISE-UP LIGHT Health Community Outreach and Transition
25 Stephanie Kwiatk MCHC/RISE-UP Mass communication in public health
26 Alesia Robinson MCHC/RISE-UP Kennedy Krieger Institute Phelps Center for Cerebral Palsy and Neurodevelopmental
Medicine
27 Samara Deleon MCHC/RISE-UP B'More 4 Healthy Babies
28 Monica Gapud MCHC/RISE-UP Integrating clinical practice with public health
29 Beverly Dahn MERIT Science of Medicine Internship: Autism
30 Kahlid Fowlkes MERIT Science of Medicine Internship: Autism
31 Christiona Harris MERIT Science of Medicine Internship: Tuberculosis
32 Karen Hernandez MERIT Science of Medicine Internship: Multiple Sclerosis
33 Lidia Hernandez MERIT Science of Medicine Internship: Fission Yeast
34 Elizabeth Cosby P-STAR Effect of Mutant DISC1 Expressed in Astrocytes on Cognitive Performance in the Radial Arm
Maze
35 Saarang Deshpande P-STAR Astrocytic ALDH7A1 Pathophysiology: Localization and Mechanism
36 Francisco Dominguez
P-STAR Social interaction and mTOR activity in Notch mouse models
37 Elizabeth Koplas P-STAR Developing Methods for Next Generation Sequencing to Examine Circulating miRNAs in
Psychiatric Disease
38 Serena Lao P-STAR Determining Off-Target Effects from the CRISPR/Cas9 Targeting of Schizophrenia-
Associated DPYSL2 Gene
39 Emily Merfeld P-STAR Early postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a
conditional neurodevelopmental mouse model of DISC1
40 Phillip Nantawisarakul
P-STAR Microglia Ablation and Reinfiltration During Rodent Brain Development
41 Madeline Pifer P-STAR Oxygen-independent upregulation of HIF1 in DISC1 knockdown models
42 Ali Abdel-Halim PCCM Quality Improvement for Intensive Care Unit Triage
43 Selom Avotri PCCM Lung Transplant Evaluation in Referred Outpatients
44 Jasmine Brown PCCM Antitussive Effects of Auranofin
45 Kathleen Carino PCCM Caspase Has a Role in the Recovery of Endothelial Barrier Integrity After Thrombin-
induced Disruption
46 Samantha Casimir PCCM Survival of Bacterial Cells with Misregulated Cell Wall Machinery
47 Shaquille Charles PCCM Idiopathic Pulmonary Fibrosis: Utilizing Electronic Health Records for Clinical Research
on Rare Diseases
48 Christopher DaSilva
PCCM Airway Macrophage Black Carbon as a Marker of Indoor Air Pollution
49 Maria Paula Hazbon
PCCM Academic Productivity of Interventional Pulmonology Training Programs
50 Rachel Howard PCCM Endothelial Nitric Oxide Synthase Involved in Early Right Ventricular Remodeling in
Pulmonary Hypertension
51 Brennan Boyle SIP The Role of ErbB2 and EGFR Kinase on Cardiac Hypertrophy Protein Expression
52 Prerana Chatty SIP The role of the hepatic estrogen receptor in regulating metabolism
53 Rachel de Barros Oliveira
SIP Genetic modifiers of congenital heart defects in a Down Syndrome model
54 Andrew Flatley SIP Impact of Sonic Hedgehog Agonist on Cerebellar Development in the Dp(16)1Yey/+ Mouse
Model of Down Syndrome
55 Marissa Gionet-Gonzales
SIP
56 Natalie Hamilton SIP Effects of S-palmitoylation on Neuropilin trafficking and localization
57 Kelsey Hopland SIP Characterization of neuron-specific proteasome
58 Errol Hunte, Jr. SIP Impact of Age on the Metabolism of the Anti-HIV Drug Maroviroc
59 Nikhil Adapa SURE Role of Mesenchymal Stem Cells in ASPN Expression
60 Kelly Humphreys SURE Expression Profile for Cancer/Testis Antigens in Prostate Cancer Cell Lines
61 Nadeen Ibrahim SURE HOXB13 Interactions with Androgen Receptors in Prostate Cancer - HOXB13 is a transcription factor that is specific to prostate development. It is also expressed in adults. To add, it was found
that it has the ability to interact with the androgen receptor, and the androgen receptor
signaling is an importance signaling pathway in prostate cancer. Characterizing the interaction between HOXB13 and androgen receptor will
offer new insight on the role of HOXB13 in prostate cancer carceniogenesis.
62 Cara Lang SURE Tissue-Specific Minicircle Gene Expression Vectors
63 Ashwin Monian SURE Genes differentially expressed in Prostate Cancer EMT
64 Zimuzoh Orakwue SURE Novel way of intratesticular testosterone production in sickle cell mice-effect on NO
signaling in the penis.
65 John Patterson SURE Silodosin inhibits cell growth of bladder and prostate cancers through down-regulation of
ELK1 in vivo
66 Kayla Prater SURE Role of STAT3 in prostatitis-induced epithelial proliferation and cancer cell growth and survival
67 Allison Reinhardt SURE TNF-α Is Increased Following Bilateral Cavernous Nerve Injury, Leading to Enhanced
Recruitment of Neurotoxic Macrophages
68 Sounak Roy SURE CXC Chemokine Receptors 4/7 in Prostate Cancer Bone Metastases
69 Thomas Valente SURE Visualization of Androgen Receptor Transcripts Encoding Discrete Functional Domains In
Metastatic Castration-Resistant Prostate Cancer Tumor Biopsies
70 Daphne Schlesinger
Individual Research
Shape Memory Effect of Anisotropic Poly(D,L-lactic acid) Microparticles.
71 Diana Hla CTY The Effect of Hydrophobic Domain Mutation on SARS CoV E Protein Oligomerization
72 Eunnie Lee CTY Question Complexity in Deductive Reasoning:The Impact of Number of
Propositions during Logic Processing
73 Caitlin Hogan CTY Post-Synthesis Surface Modification of PbS Colloidal Quantum Dot Optical Properties for
Solar Photovoltaics
74 Joshua Kasanjian CTY Effects of Exercise on Mitochondrial DNA Copy Number
75 Domenick Suarez CTY Human Opossum Epigenetic Similarities in DNA Methylation
76 Joseph Martin CTY Performance of Acutely Stressed C57/BL6 Mice in a Reversal Learning Task and Its Use for
Mouse Models of Schizophrenia
77 Ankur Sundara CTY Using Algorithms on Splice Graphs to Identify Splicing Events in Plants
78 Leonard Reid CTY Building a More Efficient Mechanism to test Memory Deficiency in Kabuki syndrome
Session 2 (2:00-3:00)
# Name Program Title 1 Shivani Pandey CCB "Methods for Aegilops tauschii BAC pool
assembly validation”
2 Rebecca Panitch CCB “Replication of Schizophrenia and Bipolar Disorder RNA Seq Analysis”
3 Shannon Rainsford CCB From A to B: An Enrichment Analysis of Subcompartments in Topologically Associated
Domains
4 Kayla Scharfstein CCB "Identifying Microbes from rRNA in Whole Genome Sequencing Experiments"
5 Dhruv Shankar CCB “Evaluating the accuracy of genome assembly with RNA-seq data”
6 Ankur Sundara CCB "Detecting Splicing Events in Plants Using Splice Graphs"
7 Sara Wang CCB "SRA sex prediction using genomic data"
8 Darren Davis DAASI
9 Alicia Lee INBT Bosutinib-Loaded Nanofibers for Inhibiting Cancer Cell Migration
10 Jaron Mackey INBT Self-Assembly Study of C12-FFEE, Ac-FFEE, and Ac-EEEE
11 Prathik Naidu INBT Towards the Rational Design of Potent Peptide Antibiotics
12 Jean Rodríguez Díaz
INBT Direct Reprograming of Fibroblast into Schwann cells
13 Joel Tyson INBT Mapping the Receptor JHA1's Role in the Endocytosis of Aplha-synuclein
14 Casey Vantucci INBT Multiple siRNA Delivery Using Bioreducible Polymeric Nanoparticles for Treatment of
Primary Human Brain Cancer Cells
15 Keclee evette INBT Effects of Shear Stress on the Proliferation and Morphology of HUVEC and dHBMEC Cell
Populations
16 Nahom Yimam INBT Effects of Shear Stress on the Velocity of HUVECand iPSC-Derived HBMEC Cell Lines
17 Shadora Robinson JHIBS Can Exosomes from ATP-Stimulated Astrocytes Reduce Neuronal Cell Death
18 Shamon Thomas-Green
JHIBS Sexual and Religious Obsessions and OCD
19 Montrell Vass JHIBS Isolating Skill Learning Using Point-to-Point Task Training
20 Daniel Gramling JHIBS Optimizing Exosome Purification from Serum and CSF
21 Sai Ruthwik JHIBS Correlation of Patient Perception of Gait and Balance with Validated Objective Measures
22 George Hseeh JHIBS The Neuroprotective Effect of Osteopontin on Cultured Neurons
23 Katherine Groesbeck
MCHC/RISE-UP Aftercare Clinic
24 Jalesa Hobson MCHC/RISE-UP Kennedy Krieger Institute cerebral palsy work
25 MCHC/RISE-UP Kennedy Krieger Institute Neuromotor Disorders work
26 Erika Castriz MCHC/RISE-UP Nutritional program for pre-teens
27 Cameron Wade MCHC/RISE-UP Native American Lifelines work
28 Jamia Marriott MERIT Science of Medicine Internship: Prostate Cancer
29 Josh Neal MERIT Science of Medicine Internship: Breast Cancer
30 Taylar Reed MERIT Science of Medicine Internship: HIV
31 Precious Tatum MERIT Science of Medicine Internship: Asthma
32 Savannah Tripp MERIT Science of Medicine Internship: Prostate Cancer
33 Wesley Godfrey PCCM Use of the Inspirotec as a Novel Sampler for Particulate Matter
34 Brittney Gordon PCCM The Effect of Heat and Humidity on Asthma Morbidity among Urban Children
35 Tiarra Joell PCCM Defining Asthma Pathology Associated with Airway Acidification through a Molecular Window of the Ovarian Cancer G Protein-
Coupled Receptor 1
36 Carolina Larrain PCCM The Regulation of NHE1 by Calpain in Pulmonary Arterial Smooth Muscle
37 Nichole Legaspi PCCM The Role of Angiotensin Type II Receptors in Oxidative Stress Injury
38 Jessica Nino de Rivera
PCCM The effect of healthcare satisfaction on medication adherence and blood pressure control
in adolescents with chronic kidney disease
39 Jose Reyes PCCM The role of CD36 and TRPV4 in reactive oxygen species induced calcium influx in human
lung microvascular endothelial cells
40 Arrix Ryce PCCM Histone H1-Lamin C Interactions
41 Abby Barger Stanley Scholars CMV and Associated Cognitive Decline: An In Depth Analysis of Antibody Binding Patterns
42 Nico Clarke Stanley Scholars Novel Exon Discovery in the Human Brain
43 Erika Glaubitz Stanley Scholars The effect of low-protein diet on chronic Toxoplasma gondii infection
44 Morgan Greene Stanley Scholars Optimizing PCR-based methods to assess neutralization of the latent HIV reservoir by
bNAbs in perinatal infection
45 Emily Krach Stanley Scholars Examining Novel Intergenic Transcripts Containing Repetitive Elements Dysregulated in
Psychiatric Disease
46 Cindy Louis Stanley Scholars Milk protein association with phases of bipolar disorder
47 Wei Feng Ma Stanley Scholars Innate Immune Response to An Intraperitoneally Administered Foodborne
Pathogen Changes Mouse Intestinal Morphology and Tight Junction Protein
Expression
48 Jamie Yang Stanley Scholars Toxoplasma affects dopamine neurotransmission: potential mechanisms
49 Stacey Alston SARE Investigating the Role of Neuropilin-2 in retinal ganglion cell projections to the dorsal lateral
geniculate
50 Grace Ayole SARE PALM Imaging of E. coli RNAP in different conditions
51 Adam Elsaidy SARE Role of Myosin II in defining the mechanics of Pancreatic Cancer
52 Siri Keyaka SARE Phenotypic Analysis of Murine Polycystic Kidney Disease (PKD)
53 Princess Massaquoi SARE Validation of histone H3K4 trimethylation of OPRM1 in persistent pain
54 Tashanna Sands SARE Investigating the effects of constituitively active RAS proteins on McF10A cell migration,
proliferation, and survival
55 Natalie Suarez-Perez
SARE Species Differences in metabolism of anti-HIV drug, maraviroc
56 Ayende Watson SARE Dual Specificity Phosphatase 19 (DUSP 19) is a newly discovered gene localized in the
centrosome that regulates cell migration and adhesion
57 Luis Milburn SIP Optimization of chromatin immunprecipitation for low cell numbers
58 Michelleine Modeste
SIP Evaluating the Effects of ECM Stiffness on C2C12 Myogenesis for Optimiazation and
Application to ASC's Myogenesis in a 2 Dimensional Culture
59 Daymond Parrilla SIP Monitoring Plk4 kinase activity in living cells
60 Diana Price SIP Adapting BioID to enable identification of host targets of Legionella viruence proteins
61 Mark Ren SIP A novel gene-environment mouse model for Parkinson's Disease using LRRD2G2019S and
MPTP
62 Daniella Rodriguez SIP Discovering novel kinases in the Hippo pathway
63 Bianca Romo SIP A Screen for Transmembrane Proteins that Promote Cell-Cell Fusion
64 Michaela Siver SIP Identifying Antibodies for Imaging of Copper Transporter CTR1 in Enteroids
65 Imani Williams SIP Optimizing CRISPR-Cas9 Genome Editing in Fission Yeast
66 Destiny Hines DAASI
67 Anthony Neville DAASI
68 Elizabeth Scriber DAASI
69 Juan Tucker DAASI
70 Joe Paggi CCB Graph-based alignment of DNA sequence to a population of genomes
71 Benjamin Aladejebi CTY Platelet Endothelial Interactions
72 Jessica Liu CTY Shape Analysis of the Auditory Cortex in Deaf Babies
73 Muriel Leung CTY Automated Processing of Tobacco News Articles
74 Angel Delgado CTY Generating Randomized DNA Pools of significant Protein Binding Regions
75 Alissa Johnson CTY Motivation as a Predictor of Success in Cognitive Training
76 Stefan Best CTY Effects of Lithium and Stress on Wnt Signaling in Bipolar Disorder Patients
77 Maya De La Torre
CTY Latent Cell Reversal in Ex Vivo Cell Cultures and HIV Patients: Predictive Computational
Models
78 Elsa Salido
CTY IncRNA Correlation with Leukemic Model Cells
79 Breanda Bzaringa JHIBS
Outstanding Students
Assefa Akinwole
Leadership Award Gilman High School
SARE
Alison Cruz
Professionalism Award Baltimore Polytechnic Institute
Centro SOL
Jose Dominguez
Community Involvement Award Current School
Centro SOL
Karen Hernandez
Leadership in Science Western High School
MERIT
Rafael Leon-Chavez
Passion for Learning Award Baltimore Polytechnic Institute
Centro SOL
Yaslin Machuca
Leadership Award Baltimore City College
Centro SOL
Natalie Suarez-Perez
Passion for Learning Award Roland Park County School
SARE
Yarnee Whitacker
Dedication to professional career pursuit REACH! Partnership School
MERIT
Anthony Neville
Passion for Learning DAASI
Diamond Eveline
Leadership DAASI
D'kai Vanlandingham
Professionalism DAASI
Sky Garner
Most Improved
DAASI
Acknowledgements
We are grateful our corporate sponsor, PNC Bank, for supporting the symposium, and for their
commitment to advancing education opportunities and academic programming for Baltimore
City youth.
Special thanks for the additional financial supports that made the Hopkins C.A.R.E.S. Summer
Symposium a success: Office of the Vice Dean for Education, Office for Student Diversity,
Summer Internship Program Basic Science Institute, The Johns Hopkins Internship in Brain
Science Program (National Institute of Mental Health R25-MH10071), and Pulmonary and
Critical Care Medicine Summer Internship Program.
Organizing Committee
Lori Brando, PhD: Assistant Professor and Program Coordinator for Stanley Summer Scholars Program
Amanda Brown, PhD: Director of Johns Hopkins Internship in Brain Science
Camille Bryant: Academic Program Administrator for Institute for NanoBioTechnology
Chiquita A. Collins, PhD: Associate Dean Office of Diversity and Cultural Competence
Ranice Crosby: Academic Program Administrator for Biophysics for Baltimore Teens
Frank Molina: High School Program Director, Thread, and Director for Diversity and Academic Advancement Summer Institute
Warren Grayson: Director of RISE (Reaching Inner city youth through Scientific Education)
Jasmine Griffin: Office Assistant for Office for Student Diversity
Tahirah Hall: Administrative Supervisor Summer Internship Program Coordinator for Pulmonary and Critical Care Medicine Summer Internship Program
Cathryn Kabacoff: Research Technologist for Summer Academic Research Experience
Stephanie Landicho: Program Director for Medical Education Resources Initiative for Teens
Eric Lee: Academic Service Specialist for Summer Internship Program
Yukiko Lema: Program Manager for Psychiatry Summer Training and Research Program
Stephanie Lechich: Research Program Assistant for Psychiatry Summer Training and Research Program
Rachelle Lott: Academic Program Assistant for Summer Internship Program
Tyler Mains: Founder and Adviser for Medical Education Initiative for Teens
Vicky Schneider: Center for Talented Youth Program Manager for Summer Research
Jungsan Sohn, PhD: Director of Biophysics Research for Baltimore Teens
Daniel Teraguchi, Ed.D: Chair, Hopkins C.A.R.E.S. Summer Symposium, Assistant Dean for Student Affairs, Director of Office for Student Diversity, Assistant Professor of Pediatrics,
Monica Guerrero Vazquez: Program Coordinator for Centro SOL
Ann Vukelich: Administrative Coordinator for Center for Computational Biology Summer Internship Program
Catherine L. Will: Program Manager for Summer Internship Program
David “Brandy” Yeater: Research Administrative Manager for Summer Urological Research
Experience at the Brady Urological Institute