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1,000,000,0007,000,874
6587423
81
US $ investmenthours of workexperimentsresearchersyearsdrug
Pharma is experience challenges
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Pharma R&D is adapting for the future
Focus is on:
•Productivity, ROI
•Externalization & Collaboration
•Diversification
•Personalized Medicine
We want to contribute
• Dedicated Science, Medical Information company• 7,000 Employees• PhD scientists, information
scientists, publishers
• Extensive scientific network• 600,000 authors• 300,000 reviewers• 70,000 journal editors and
board members
• Publish• 300,000 articles/yr• 2,000 journals• 20,000 books• Leading titles (e.g. Cell, The
Lancet)
• Global STM coverage• 18,000 titles used in
abstracting, indexing• Extensive patent coverage
(USTPO, EPO, WPO)
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Our information spans Pharma’s value chain
TargetValidation
Lead ID
LeadValidation PoCPhase
IPhaseII
PhaseIII
PhaseIVToxicity Safety Post
LaunchTargetFinding
Trusted External R&D
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Evolving with Pharma R&D
I. Identify relevant knowledge that drives R&D
II. Disseminate content to scientists, R&D decision makers
III. Make content interactive and actionable
Creating Insight
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Identify relevant content that drives R&D
... the past... the present
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... the past
Disseminate Content to Scientists, R&D decision makers
... the present
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... The past
Make Content Interactive and Actionable
... The present
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Why is Elsevier here?
Novartis announces USD 1 billion investment to build largest pharmaceutical R&D institute in China Press Release November 2009
Because our customers have come here....
... And our new customers are here
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What is Reaxys?
A workflow solution for researchers in chemistry, drug discovery and related scientific areas
Using Reaxys researchers can
• Easily access validated reaction and substance data, ranking and filtering for relevant results
• Source available chemicals• Plan and optimize synthetic route• Export and share results for immediate action in the lab
An extensive repository of reaction and substance property data, Reaxys includes:
• Organic, inorganic, organometallic chemistry from 400 journals
• Coverage from 1771 - present• World Patent Office, European Patent Office and US English
language patents from the major chemistry patent classes
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Reaxys extracts valuable chemical properties and reaction details from journals and patents.
1H NMR
300 MHZ
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Five good reasons to use Reaxys
1. The wealth of experimentally validated data which can be searched, filtered and ranked to find the most relevant answer to a specific question quickly.
2. Functionality beyond data searching: synthesis planner, results management, smart analysis tools for fast evaluation.
3. No user or usage limits: flat-rate for institution-wide access at any time.
4. The intuitive interface and online educational material help reduce your training efforts.
5. Interoperable: linking to SciVerse Scopus, full-texts at publishers and patent offices. Access to your own library settings via OpenURL resolver is possible.
Professor Peter Johnson, University of Leeds
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What our customers say:
Peter Johnson, University of Leeds
Reaxys is used by 24 of the Top-25* ranked academic chemistry research programs
Src: 2011 www.arwu.org
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Reaxys Case Study:
Finding coumarin glycosides
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What we will do
• Search by structure
• Filter By substructure, spectra, and bioactivity
• Export to a spreadsheet
• Create a Synthesis Plan
• Use the Form-based and Advanced Search Tabs
• Search by Keyword
17
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HO
O
Examples:Isolate the substances that
have NMR data and antibacterial activity
Find coumarin glycosides
O
O
O
O
O
O
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coumarin
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glucopyranose
5
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*bac*
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antibacbacterio
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catalyst
*’
palladium
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Reaction type
hydrogenation
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Coumarin NEXT glycosideC*marin* NEXT glycosid*
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What you have seen
• Search by structure
• Filter By substructure, spectra, and bioactivity
• Export to a spreadsheet
• Create a Synthesis Plan
• Use the Form-based and Advanced Search Tabs
• Search by Keyword
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Thank You
• Reaxys training materials can be found at www.reaxys.com/info
• Contact Reaxys Customer Support at: [email protected] if you would like to schedule a Reaxys Advanced Training webinar
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Thank you
• Questions?