JANET HEMINGWAY CBE, FRS, DSc, PhD, BSc, FRCP (Hon), FMedSci, FRES (Hon), (foreign associate National Academy of Sciences USA), FAAM

CURRICULUM VITAE DETAILS

Date of Birth: 13.06.1957

Current Positions: Director of the Liverpool School of Tropical Medicine 2001 to dateAdvocacy, Resources and Mobilisation, Innovative Vector Control Consortium (IVCC) August 2013 to date

Academic qualifications:

1978 BSc, First Class, Genetics and Zoology, University of Sheffield1981 PhD on 'The biochemistry and genetics of insecticide resistance in Anopheles' University of London (London School of Hygiene and Tropical Medicine)2009 DSc, Medicine, University of Sheffield2015 DSc, Medicine, University of Warwick Positions held:

1981-1982 Lecturer in Toxicology, University of California Riverside, USA. 1982-1984 MRC Research Fellow, London School of Hygiene and Tropical

Medicine (LSHTM)1984-1993 Royal Society Junior Research Fellow, LSHTM1986 Secondment to CSIRO (Animal Health Division), Brisbane, Australia

(for a six month period)1992-1993 Senior Lecturer, Department of Medical Parasitology, LSHTM (Co-

Appointment with the Royal Society Fellowship)1994–2001 Biosciences Director of Research and Professor of Applied Molecular

Entomology, University of Wales Cardiff2005-2013 CEO of Innovative Vector Control Consortium (IVCC)

Official Appointments:

Vice President Royal Society of Tropical Medicine 2005 to 2008Bill and Melinda Gates Foundation Malaria Strategy Group 2007 to 2010Google Foundation Emerging Infectious Diseases Strategy Group 2008 to dateRoyal Society Committee Member for Dorothy Hodgkin Biological Fellowships, 1995 to 2009.MRC Special Advisory Panel in infection and immunity 2004 to date.President Science and Medicine Panel, British Association for the Advancement of Science 2007 to 2009.

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Member of the World Health Organization Expert Committee on Insecticides and Insecticide Resistance since 1985.Academy of Medical Sciences Fellowships Panel 2007 to 2011Malaria Elimination Group member (USA) 2007 to date.Panel Advisor AusAid and Global Fund for Pacific Rim Malaria Control Operations 2007 to dateMember of the Advisory Board to the World Bank/WHO Onchocerciasis Control Programme in West Africa 1986 - 1989.Advisor to the Anti-Malaria Campaign Sri Lanka 1984 to date. Advisor to the Ministry of Health Cuba 1989 to 2007.The sole academic member of Joint Industries Pesticide Resistance Action Committee 1990 to 2004.IOPERM Cotton Crop Resistance Management Steering Group member for cotton crop pest control in China, 1996. Scientific Advisor and panel member for Aga Khan University, Pakistan since 2003 Chair of this group since 2007.Keystone Symposia Chairperson and Organising Committee member 2001 - 2007.EMBL bioinformatics workshops organising committee 2003 - 2007.Member of the NIH panel on infectious diseases 2000 - 2005Imperial College London, Post-graduate training oversight group 2004.BBSRC Rothamsted Res Institutional Review Group 2005.MacArthur Foundation Biology of Disease Vectors Course Organiser and steering committee member 2003 - 2008.FNIH Oversight panel member for Gates Grand ChallengesWellcome Trust MAP Advisory committee memberWellcome Trust Infectious Disease Fellowship panel member 2011 to dateGovernor, Royal Liverpool & Broadgreen University Hospitals NHS TrustOak Foundation specialist advisor 2011 to 2013

Awards:Commander of the British Empire (CBE) for services to the Control of Tropical Disease Vectors 2012Knowledge Leader of the Year 2012, MerseysideFellow of the Royal Society 2011Fellow of American Academy of Microbiology 2011Foreign associate National Academy of Sciences USA 2010Honorary Fellow and elected life member Royal Society of Entomology 2010Honorary Fellow of the Royal College of Physicians 2008Fellow Academy of Medical Sciences 2006Welsh Woman of the Year 1999.Tropical Entomology Medals from Indonesia and Cuba 1997 and 1994.Merseyside Woman of the Year, (public services) 2003Welsh Development Agency undergraduate supervisor of the year 1998 and 2001DTI National Award Winner for Industry-Academe collaboration 1999 (presented in 10 Downing Street)Invited and Keynote speaker at numerous meetings including The Royal Society (UK) and the National Academy of Sciences (USA).

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Editorial Boards:Insect Biochemistry and Molecular BiologySalud Publica de MexicoProceedings National Academy of Sciences

Institutional and Academic commitments:

After being instrumental in the re-organisation of the University of Cardiff’s Biosciences and Biomedical Departments, resulting in a re-structuring of undergraduate teaching, merger of departments and move from two RAE grade 3As to two Grade 5s I was head-hunted in 2001 to become the head of the world’s oldest Tropical Medicine Institution in Liverpool. This was a challenging role as the Institution is a complex independent Charity with an annual turn-over of approximately £45Million, which indirectly receives its HEFCE income through an affiliation with the University of Liverpool. It provides the infectious disease in- and out-patient cover for the NHS for the North of England (where we provide infectious diseases staff for the major local hospitals and run an in house NHS and private travel clinic), runs extensive post-graduate and specialist undergraduate biological and medical courses, but with the bulk (80%) of the institutions income coming from research (with research covering both medical and veterinary areas).

Since 2001 I have restructured the Institution, turned it around financially, and have raised £35million of capital grants to build new state of the art facilities, which has allowed the Institution to expand substantially. I had sole responsibility for raising the capital funding for the new School building from a variety of sources. This was clearly a major undertaking, but this, alongside the financial controls that have been put in place has put the Institution on a much sounder footing than it has been at any stage during the last 50 years. LSTM’s growth was strategically driven and is part of a coherent plan formally adopted in 2002, with five year reviews, to ensure that the School is recognised as the premier School of Tropical Medicine in the coming decades.

In addition to the staff in Liverpool I also have oversight of one of four Wellcome Trust Tropical Centres with approximately 40 staff based out in Malawi (a joint venture with Liverpool University) and centres in Tanzania and Ecuador. The School has a wholly owned subsidiary company, Well Travelled Clinics, undertaking the private travel medicine work. I was responsible for the successful spin out of this business from within the School and have also spun out the Gates funded IVCC programme into a separate legal entity and attracted a further $50Million of new funding from the Gates Foundation.

In late 2005 I reduced my percentage time as Head of the Institution to 50%, with the full agreement of LSTM’s Board of Trustees and became founding member and CEO of the Bill and Melinda Gates Funded Innovative Vector Control Consortium. This was established as a new Product Development Partnership for stimulating the development of new public health pesticides for malaria and dengue control, with an initial $50million investment. This required engagement of multinational companies, academia and overseas Ministries of Health in Africa and Latin America in large scale projects aimed at transforming the way that malaria,

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dengue and other vector borne diseases are controlled. The first new products from this venture are now coming to the market.

While running both the Liverpool School and the IVCC I have continued to run an active research group, although I took the decision in 2007 not to directly supervise any further PhD students and to start to wind down my direct role in the research, transferring the activity to three senior post-doctoral staff to take forward. Currently I lead a group of twenty-nine research scientists at post-doctoral and post-graduate level. The group is unique in that it covers the full spectrum of insect vector control from bench to bush. We have cutting edge work on going on the biochemistry and molecular biology of specific enzyme systems associated with xenobiotic resistance through to large scale operational programmes in Mexico and Mozambique putting control theory into practice. Grant holder on current projects in excess of £29 million. Overseas projects currently in Cambodia, Mozambique, Mexico, South Africa, Sri Lanka, Thailand, and USA. Extensive experience of working in tropical regions of Africa, Asia and South America over a 20 year period. In addition I have been a part of the International consortia that have had responsibility for undertaking the Anopheles gambiae and Aedes aegypti mosquito genome sequences and I am currently driving phase 1 of the Culex quinquefasciatus genome programme with the normalised cDNA libraries from a range of pathogen infected mosquitoes being made in my lab. I also act as the lead for LATH for vector M & E on the PMI programme with RTI as the lead organisation.

Current Research Grants (All as PI): Total Value of Current Research Grants approximately £33.4Million. An additional £30Million in capital grants has been raised over the last 5 years in addition to this.

Gates Foundation

Topic: Innovative Vector Control Consortium (re-financing)Value: US$50,726,000 (£26,000,000)

Topic: Innovative Vector Control ConsortiumValue: US$50,726,000 (£26,000,000)

Topic: GIS mapping of drug and insecticide resistance in southern AfricaValue: US$300,000 (£214,200)

Topic: Malaria PhD studentshipsValue: £240,000

National Institute of Health, USA

Topic: Resistance management in southern African malaria vectorsValue: US$2,100,000 (£1.5million)

Department for International Health (DFID)

Topic: Control of outdoor biting vectors in Cambodia4

Value: £1,300,000

Medical Research Council

Topic: Does insecticide resistance affect disease transmissionValue: £309,000

Topic: Molecular approaches to the control of insect vector borne diseaseValue: £65,000

The Wellcome Trust

Topic: Capital development of Centre for Tropical infectious DiseasesValue: £2,000,000

Topic: QTL mapping and field validation of pyrethroid resistance in Anopheles funestus (Sponsor role C. Wondji as senior fellow)Value: £1,200,000

Topic: Positional cloning of pyrethroid resistance genes from Anopheles gambiae

Value: £486,000

Topic: Characterization of a novel class of Anopheles gambiae glutathione S-transferases genetically linked to the inheritance of DDT resistance. Value: £196,000

Topic: Insecticide resistance in Anopheles albimanus. Value: £71,600

Topic: GIS mapping of the movement of insecticide resistance genes through Anopheles populations. Value: £178,000.

Topic: The affect of insecticide resistance on vectorial capacity.Value: £170,000

Topic: Metabolic resistance in Anopheles funestus in South Africa. Tropical Development Award. Value: £88,600.

Topic: Microarray Centre for insect vectors of diseaseValue: £150,000

Topic: Population structure of Anopheles albimanus. Value: £60,359

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Topic: Molecular approaches to dengue control through manipulation of Aedes aegyptiValue: £18,000

Topic: Molecular characterisation of glutathione S-transferases in the Anopheles gambiae and An. dirus complexesValue: £18,000

Topic: Monitoring insecticide resistant Aedes aegyptiValue: £18,000

Topic: Molecular characterisation of insecticide resistance in the Anopheles culicifacies complex

Value: £18,000

Topic: Pyrethroid resistance in Aedes aegypti. Value: £18,000

European Union

Topic: Species composition and insecticide resistance status of SE Asian vectorsValue: Euro 560,000

Shell

Topic: Resistance in malaria vectors and parasites in Nigeria Value: £54,000

Outside Interests

Combined with my role of mother of a 23-year-old daughter and the general interests of reading and walking, for the last 20 years I have played competitive squash up to county level. This was curtailed three years ago by snapping my Achilles tendon. I also own, breed and train a small herd of pure bred Arabian horses for showing, cross country jumping and endurance riding.

PUBLICATION LIST (FULL REFEREED ARTICLES ONLY)

1. Hemingway, J. 1980. Modification of the adult resistance test kit to measure knock-down rates. Trans. Roy. Soc. Trop. Med. Hyg. 74:677 - 679.

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2. Hemingway, J. 1982. Genetics of organophosphate and carbamate resistance in Anopheles atroparvus . J. Econ. Ent. 75:1055-1058.

3. Hemingway, J. 1982. The biochemical nature of malathion resistance in Anopheles stephensi from Pakistan. Pest. Biochem. Physiol. 17:149-155.

4. Hemingway, J. and G. Davidson. 1983. Resistance to organophosphate and carbamate insecticides in Anopheles atroparvus . Parassitologia 25:1-8.

5. Hemingway, J. 1983. Biochemical studies on malathion resistance in Anopheles arabiensis from Sudan. Trans. Roy. Soc. Trop. Med. Hyg. 77:477-480.

6. Hemingway, J. 1983. Add on drugs fight insecticide resistance. New Scientist 97:649.

7. Hemingway, J. and G. P. Georghiou. 1983. Studies on the acetylcholinesterase of Anopheles albimanus resistant and susceptible to organophosphate and carbamate insecticides. Pest. Biochem. Physiol. 19:167-171.

8. Hemingway, J. 1983. The genetics of malathion resistance in Anopheles stephensi from Pakistan. Trans. Roy. Soc. Trop. Med. Hyg. 77:106-108.

9. Hemingway, J., M. Rowland, and K. E. Kissoon. 1984. Efficacy of Pirimiphos methyl as a larvicide or adulticide against insecticide resistant and susceptible mosquitoes (Diptera: Culicidae). J. Econ. Ent. 77: 868-871.

10.Hemingway, J. 1984. The joint action of malathion and IBP against malathion-resistant and susceptible strains of Anopheles stephensi . Bull. Wld Hlth Org. 62:445-449.

11.Hemingway, J. and G. P. Georghiou. 1984. Baseline esterase levels for anopheline and culicine mosquitoes. Mosq. News 44:33-35.

12.Hemingway, J. and G. P. Georghiou. 1984. Differential suppression of organophosphorus resistance in Culex quinquefasciatus by the synergists IBP, DEF and TPP. Pest. Biochem. Physiol. 21:1-9.

13.Hemingway, J., C. A. Malcolm, K. E. Kissoon, R. G. Boddington, C. F. Curtis, and N. Hill. 1985. The biochemistry of insecticide resistance in Anopheles sacharovi : comparative studies with a range of insecticide susceptible and resistant Anopheles and Culex species. Pest. Biochem. Physiol. 24:68-76.

14.Hemingway, J. 1985. Malathion carboxylesterase enzymes in Anopheles arabiensis from Sudan. Pest. Biochem. Physiol. 23:309-313.

15.Hemingway, J., C. Smith, K. G. I. Jayawardena, and P. R. J. Herath. 1986. Field and laboratory detection of the altered acetylcholinesterase resistance genes which confer organophosphate and carbamate resistance in mosquitoes (Diptera: Culicidae). Bull. Ent. Res. 76:559-565.

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16.Hemingway, J., Y. Rubio, and K. E. Bobrowicz. 1986. The use of ELISA demonstrates the absence of Culex organophosphorous-resistance-associated esterases in Anopheles species. Pest. Biochem. Physiol. 25:327-335.

17.Hemingway, J., K. G. I. Jayawardena, I. Weerasinghe, and P. R. J. Herath. 1987. The use of biochemical tests to identify multiple insecticide resistance mechanisms in field-selected populations of Anopheles subpictus Grassi (Diptera: Culicidae). Bull. Ent. Res. 77:57-66.

18.Herath, P. R. J., J. Hemingway, I. S. Weerasinghe, and K. G. I. Jayawardena. 1987. The detection and characterization of malathion resistance in field populations of Anopheles culicifacies B in Sri Lanka. Pest. Biochem. Physiol. 29:157-162.

19.Rowland, M. and J. Hemingway. 1987. Changes in malathion resistance with age in Anopheles stephensi from Pakistan. Pest. Biochem. Physiol. 28:239-247.

20.Villani, F. and J. Hemingway. 1987. The detection and interaction of multiple organophosphorus and carbamate insecticide resistance genes in field populations of Culex pipiens from Italy. Pest. Biochem. Physiol. 27:218-228.

21.Bonning, B. C., C. A. Malcolm, and J. Hemingway. 1988. Purification and characterization of acetylcholinesterase from Culex pipiens . Pest. Science 24:278-280.

22.Herath, P. R. J., K. G. I. Jayawardena, J. Hemingway, and J. Harris. 1988. DDT resistance in Anopheles culicifacies Giles and A. subpictus Grassi (Diptera: Culicidae) from Sri Lanka: a field study on the mechanisms and changes in gene frequency after cessation of DDT spraying. Bull. Ent. Res. 78:717-723.

23.Amin, A. M. and J. Hemingway. 1989. Preliminary investigation of the mechanisms of DDT and pyrethroid resistance in Culex quinquefasciatus Say (Diptera: Culicidae) from Saudi Arabia. Bull. Ent. Res. 79:361-366.

24.El-Sayed, S., J. Hemingway, and R. P. Lane. 1989. Susceptibility baselines for DDT metabolism and related enzyme systems in the sandfly Phlebotomus papatasi (Scopoli) (Diptera: Psychodidae). Bull. Ent. Res. 79:679-684.

25.Hemingway, J., R. G. Boddington, J. Harris, and S. J. Dunbar. 1989. Mechanisms of insecticide resistance in Aedes aegypti (L.) (Diptera: Culicidae) from Puerto Rico. Bull. Ent. Res. 79:123-130.

26.Hemingway, J. 1989. A note on simple biochemical methods for resistance detection and their field application in Sri Lanka. Pest. Sci. 27:281-285.

27.Hemingway, J., A. Callaghan, and D. C. Kurtak. 1989. Temephos resistance in Simulium damnosum Theobald (Diptera: Simulidae): a comparative study between larvae and adults of the forest and savanna strains of this species complex. Bull. Ent. Res. 79:659-669.

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28.Bisset, J. A., M. M. Rodriguez, C. Diaz, E. Ortiz, M. C. Marquetti, and J. Hemingway. 1990. The mechanisms of organophosphate and carbamate resistance in Culex quinquefasciatus (Diptera: Culicidae) from Cuba. Bull. Ent. Res. 80:245-250.

29.Hemingway, J., A. Callaghan, and A. M. Amin. 1990. Mechanisms of organophosphate and carbamate resistance in Culex quinquefasciatus from Saudi Arabia. Med. Vet. Entomol. 4:275-282.

30.Peiris, H. T. R. and J. Hemingway. 1990. Mechanisms of insecticide resistance in a temephos selected Culex quinquefasciatus (Diptera: Culicidae) strain from Sri Lanka. Bull. Ent. Res. 80:453-457.

31.Peiris, H. T. R. and J. Hemingway. 1990. Temephos resistance and the associated cross-resistance spectrum in a strain of Culex quinquefasciatus Say (Diptera: Culicidae) from Peliyagoda, Sri Lanka. Bull. Ent. Res. 80:49-55.

32.Bisset, J. A., M. M. Rodriguez, J. Hemingway, C. Diaz, G. J. Small, and E. Ortiz. 1991. Malathion and pyrethroid resistance in Culex quinquefasciatus from Cuba: efficacy of pirimiphos-methyl in the presence of at least three resistance mechanisms. Med. Vet. Entomol. 5:223-228.

33.Bonning, B. C., J. Hemingway, R. Romi, and G. Majori. 1991. Interaction of insecticide resistance genes in field populations of Culex pipiens (Diptera: Culicidae) from Italy in response to changing insecticide selection pressure. Bull. Ent. Res. 81:5-10.

34.Bonning, B. C. and J. Hemingway. 1991. Identification of reduced fitness associated with an insecticide resistance gene in Culex pipiens by microtitre plate assay. Med. Vet. Entomol. 5:377-379.

35.Bonning, B. C. and J. Hemingway. 1991. The efficacy of acetylcholinesteraes in organophosphorus and carbamate resistance in Culex pipiens L. from Italy. Pest. Biochem. Physiol. 40:143-148.

36.Callaghan, A., C. A. Malcolm, and J. Hemingway. 1991. Biochemical-studies of A-carboxylesterase and B-carboxylesterase from organophosphate resistant strains of an Italian Culex pipiens (Diptera, Culicidae). Pest. Biochem. Physiol. 41:198-206.

37.Hemingway, J. 1991. The role of growth regulators and other novel compounds in vector control and resistance management. WHO/CTD/OPR/EC 91.48.

38.Hemingway, J., A. Callaghan, and D. C. Kurtak. 1991. Biochemical characterization of chlorphoxim resistance in adults and larvae of the Simulium damnosum complex (Diptera: Simulidae). Bull. Ent. Res. 81:401-406.

39.Hemingway, J., J. Miyamoto, and P. R. J. Herath. 1991. A possible novel link between organophosphorus and DDT insecticide resistance genes in Anopheles : supporting evidence from fenitrothion metabolism studies. Pest. Biochem. Physiol. 39:49-56.

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40.Hemingway, J. 1992. Genetics of insecticide resistance in mosquito vectors of disease. Parasitology Today 8:296-298.

41.Hemingway, J., G. J. Small, A. Monro, B. V. Sawyer, and H. Kasap. 1992. Insecticide resistance gene frequencies in Anopheles sacharovi populations of the Cukurova plain, Adana province, Turkey. Med. Vet. Entomol. 6:342-348.

42.Ketterman, A. J., K. G. I. Jayawardena, and J. Hemingway. 1992. Purification and characterization of a carboxylesterase involved in insecticide resistance from the mosquito Culex quinquefasciatus . Biochem. J. 287:355-360.

43.Callaghan, A., J. Hemingway, and C. A. Malcolm. 1993. The selection and genetic-analysis of esterase electromorphs in an organophosphate-resistant strain of Culex pipiens from Italy. Biochem. Genet. 31:459-472.

44.Hemingway, J., G. J. Small, and A. G. Monro. 1993. Possible mechanisms of organophosphorus and carbamate insecticide resistance in German cockroaches (Dictyoptera: Blattelidae) from different geographical areas. J. Econ. Ent. 86:1623-1630.

45.Hemingway, J., S. J. Dunbar, A. G. Monro, and G. J. Small. 1993. Pyrethroid resistance in German cockroaches (Dictyoptera: Blattelidae): Resistance levels and underlying mechanisms. J. Econ. Ent. 86:1631-1638.

46.Hemingway, J., A. J. Ketterman, S. H. P. P. Karunaratne, K. G. I. Jayawardena, and A. Vaughan. 1993. Amplified esterases A2 and B2 has resistance occurred once or several times? Proc. 1st Int. Cong. Ins. Pests Urban Envir. 1:319-328.

47.Hemingway, J. and G. J. Small. 1993. Resistance mechanisms in cockroaches - the key to control strategies. Proc. 1st Int. Cong. Ins. Pests Urban Envir. 1:141-152.

48.Karunaratne, S. H. P. P., K. G. I. Jayawardena, J. Hemingway, and A. J. Ketterman. 1993. Characterization of a B-type esterase involved in insecticide resistance from the mosquito Culex quinquefasciatus . Biochem. J. 294:575-579.

49.Ketterman, A. J., S. H. P. P. Karunaratne, K. G. I. Jayawardena, and J. Hemingway. 1993. Qualitative differences between populations of Culex quinquefasciatus in both the esterases A2 and B2 which are involved in insecticide resistance. Pest. Biochem. Physiol. 47:142-148.

50.Lindsay, S. W., P. L. Alonso, J. R. M. Armstrong Schellenberg, J. Hemingway, P. J. Thomas, F. C. Shenton, and B. M. Greenwood. 1993. A malaria control trial using insecticide-impregnated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, West Africa. 3. Entomological characteristics of the study area. Trans. Roy. Soc. Trop. Med. Hyg. 87:19-24.

51.Lindsay, S. W., P. L. Alonso, J. R. M. Armstrong Schellenberg, J. Hemingway, J. Adimah, F. C. Shenton, M. Jawara, and B. M. Greenwood. 1993. A malaria control trial using insecticide-impregnated bed nets and targeted chemoprophylaxis in a rural

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area of The Gambia, West Africa. 7. Impact of permethrin impregnated bed nets on malaria vectors. Trans. Roy. Soc. Trop. Med. Hyg. 87:45-52.

52.Mourya, D. T., J. Hemingway, and C. J. Leake. 1993. Changes in enzyme titres with age in four geographical strains of Aedes aegypti and their association with insecticide resistance. Med. Vet. Entomol. 7:11-16.

53.Peiris, H. T. R. and J. Hemingway. 1993. Characterization and inheritance of elevated esterases in organophosphorus and carbamate insecticide resistant Culex quinquefasciatus (Diptera: Culicidae) from Sri Lanka. Bull. Ent. Res. 83:127-132.

54.Prapanthadara, L., J. Hemingway, and A. J. Ketterman. 1993. Partial purification and characterization of glutathione S-transferase involved in DDT resistance from the mosquito Anopheles gambiae . Pest. Biochem. Physiol. 47:119-133.

55.Rodriguez, M., E. Ortiz, J. A. Bisset, J. Hemingway, and E. Saledo. 1993. Changes in malathion and pyrethroid resistance after cypermethrin selection of Culex quinquefasciatus field populations of Cuba. Med. Vet. Entomol. 7:117-121.

56.Hemingway, J. 1994. Insecticide resistance and its importance in malaria control. Public Health 11:6-13.

57.Jayawardena, K. G. I., S. H. P. P. Karunaratne, A. J. Ketterman, and J. Hemingway. 1994. Determination of the role of elevated B2 esterase in insecticide resistance in Culex quinquefasciatus (Diptera: Culicidae) from studies on the purified enzyme. Bull. Ent. Res. 84:39-44.

58.Bisset, J. A., E. Ortiz, M. Rodriguez, and J. Hemingway. 1995. Comparison of microtitre plate and filter paper assays of elevated esterase-based resistance frequencies in field and laboratory populations of the mosquito Culex quinquefasciatus from Cuba. Med. Vet. Entomol. 9:94-97.

59.Hemingway, J., G. J. Small, S. Lindsay, and F. H. Collins. 1995. Combined use of biochemical, immunological and molecular assays for infection, species identification and resistance detection in field populations of Anopheles (Diptera: Culicidae), In W. O. C. Symondson and E. Lydell [eds.], The ecology of agricultural pests: Biochemical approaches. Chapman and Hall, London.

60.Hemingway, J. 1995. Efficacy of etofenprox against insecticide susceptible and resistant mosquito strains containing characterised resistance mechanisms. Med. Vet. Entomol. 9:423-426.

61.Hemingway, J., S. W. Lindsay, G. J. Small, M. Jawara, and F. H. Collins. 1995. Insecticide susceptibility status in individual species of the Anopheles gambiae complex where pyrethroid impregnated bednets are used extensively for malaria control. Bull. Ent. Res. 85:229-234.

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62.Jayawardena, K. G. I. and J. Hemingway. 1995. Cysteine residues modify the electrophoretic mobility of amplified esterases associated with insecticide resistance in Culex mosquitoes. Med. Vet. Entomol. 9:341-342.

63.Karunaratne, S. H. P. P., J. Hemingway, K. G. I. Jayawardena, V. Dassanayaka, and A. Vaughan. 1995. Kinetic and molecular differences in the amplified and non-amplified esterases from insecticide-resistant and susceptible Culex quinquefasciatus mosquitoes. J. Biol. Chem. 270:31124-31128.

64.Karunaratne, S. H. P. P., K. G. I. Jayawardena, and J. Hemingway. 1995. The cross-reactivity spectrum of a polyclonal antiserum raised against the A2 esterase involved in insecticide resistance. Pest. Biochem. Physiol. 53:75-83.

65.Mourya, D. T., J. Hemingway, and C. J. Leake. 1995. Post-inoculation changes in enzyme activity of Aedes aegypti infected with Chikungunya virus. Acta Virologica 39:31-35.

66.Mumcuoglu, K. Y., J. Miller, I. Uspensky, J. Hemingway, S. Klaus, F. Ben-Ishai, and R. Galun. 1995. Pyrethroid resistance in the head louse Pediculus humanus capitis from Israel. Med. Vet. Entomol. 9:427-432.

67.Prapanthadara, L., J. Hemingway, and A. J. Ketterman. 1995. DDT-resistance in Anopheles gambiae Giles from Zanzibar Tanzania, based on increased DDT- dehydrochlorinase activity of glutathione S-transferases. Bull. Ent. Res. 85:267-274.

68.Vaughan, A., M. Rodriguez, and J. Hemingway. 1995. The independent gene amplification of indistinguishable esterase B electromorphs from the insecticide resistant mosquito Culex quinquefasciatus . Biochem. J. 305:651-658.

69.Vaughan, A. and J. Hemingway. 1995. Mosquito carboxylesterase Est2 1 (A2). Cloning and sequence of the full length cDNA for a major insecticide resistance gene worldwide in the mosquito Culex quinquefasciatus . J. Biol. Chem. 270:17044-17049.

70.Karunaratne, S. H. P. P. and J. Hemingway. 1996. Different insecticides select multiple carboxylesterase isoenzymes and different resistance levels from a single population of Culex quinquefasciatus . Pest. Biochem. Physiol. 54:4-11.

71.Peiris, H. T. R. and J. Hemingway. 1996. The effect of fenthion treatment on larval densities of insecticide resistant Culex quinquefasciatus in an urban area of Sri Lanka. Med. Vet. Entomol. 10:283-287.

72.Penilla, R. P., A. D. Rodriguez, J. Hemingway, J. L. T. Estrada, J. I. A. Jimenez, and M. H. Rodriguez. 1996. Rotational and mosaic strategies for delaying the development of insecticide resistance in mosquitoes - baseline data for a large scale field trial in Southern Mexico. pp. 401-411 In K. B. Wildey and W. H. Robinson [eds.], Proceedings of the 2nd International Conference on Insect Pests in the Urban Environment. BPCC Wheatons Ltd, Exeter.

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73.Prapanthadara, L., S. Koottathep, N. Promtet, J. Hemingway, and A. J. Ketterman. 1996. Purification and characterization of a major glutathione S-transferase from the mosquito Anopheles dirus (Species B). Ins. Biochem. Mol. Biol. 26:277-285.

74.Scharf, M. E., J. Hemingway, B. L. Reid, G. J. Small, and G. W. Bennett. 1996. Toxicological and biochemical characterizations of insecticide resistance in a field-collected strain of Blattella germanica (Dictyoptera: Blattellidae). J. Econ. Ent. 89:322-331.

75.DeSilva, D., J. Hemingway, H. Ranson, and A. Vaughan. 1997. Resistance to insecticides in insect vectors of disease: est3, a novel amplified esterase associated with est1s from insecticide resistant strains of the mosquito Culex quinquefasciatus . Exp. Parasit. 87:253-259.

76.Hemingway, J., R. P. Penilla, A. D. Rodriguez, B. M. James, W. Edge, H. Rogers, and M. H. Rodriguez. 1997. Resistance management strategies in malaria vector mosquito control. A large scale trial in Southern Mexico. Pest. Sci. 51:375-382.

77.Ranson, H., A. J. Cornel, D. Fournier, A. Vaughan, F. H. Collins, and J. Hemingway. 1997. Cloning and localization of a glutathione S -transferase Class I gene from Anopheles gambiae . J. Biol. Chem. 272:5464-5468.

78.Ranson, H., L. Prapanthadara, and J. Hemingway. 1997. Cloning and characterisation of two glutathione S-transferases from a DDT resistant strain of Anopheles gambiae . Biochem. J. 324:97-102.

79.Scharf, M. E., J. Hemingway, G. J. Small, and G. W. Bennett. 1997. Examination of esterases from insecticide resistant and susceptible strains of the German cockroach Blattella germanica (L.). Ins. Biochem. Mol. Biol. 27:489-497.

80.Vaughan, A., N. Hawkes, and J. Hemingway. 1997. Co-Amplification explains linkage disequilibrium of two mosquito esterase genes in insecticide-resistant Culex quinquefasciatus . Biochem. J. 325:359-365.

81.Hemingway, J., N. Hawkes, L. Prapanthadara, K. G. I. Jayawardena, and H. Ranson. 1998. The role of gene splicing, gene amplification and regulation in mosquito insecticide resistance. Proc. Roy. Soc. Series B. 353:1695-1699.

82.Hemingway, J. and S. H. P. P. Karunaratne. 1998. Mosquito Carboxylesterases: A Review of the Molecular Biology and Biochemistry of a Major Insecticide Resistance Mechanism. Med. Vet. Entomol. 12:1-12.

83.Hemingway, J. 1998. Resistance monitoring tools and their application to resistance management. WHO/MAL1-18.

84.Hemingway, J. and W. Brogdon. 1998 Techniques to detect insecticide resistance mechanisms (field and laboratory manual). WHO/CDS/CPC/MAL/98.6, 1-34. 1998. Geneva, WHO. World Health Organization: Dept. of Disease Prevention & Control, WHO Communicable Diseases (CDS).

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85.Hemingway, J. 1998. A practical field and laboratory manual for the mechanistic detection of insecticide resistance in insects. WHO TDR series book.

86.Karunaratne, S. H. P. P. and J. Hemingway. 1998. Identical restriction enzyme maps of the amplicons containing the Est2 1 and Est2 1 insecticide resistance genes in Culex quinquefasciatus colonies from Saudi Arabia, Tanzania and Sri Lanka. J. Natn. Sci. Council Sri Lanka 26:311-319.

87.Karunaratne, S. H. P. P., A. Vaughan, M. G. Paton, and J. Hemingway. 1998. Amplification of a serine esterase gene is involved in insecticide resistance in Sri Lankan Culex tritaeniorhynchus . Ins. Mol. Biol. 7:307-315.

88.Penilla, R. P., A. D. Rodriguez, J. Hemingway, J. L. Torres, J. I. Arredondo-Jimenez, and M. H. Rodriguez. 1998. Resistance management strategies in malaria vector mosquito control. Baseline data for a large-scale field trial against Anopheles albimanus in Mexico. Med. Vet. Entomol. 12:217-233.

89.Pinto, G. A., J. A. Quartau, J. Morgan, and J. Hemingway. 1998. Preliminary data on the sequence of a fragment of cytochrome B gene of mitochondrial DNA in Cicada orni L. (Homoptera: Cicadidae) in Portugal. Bolm Soc. Portugese Ent. Soc. 188:57-66.

90.Prapanthadara, L. A., H. Ranson, P. Somboon, and J. Hemingway. 1998. Cloning, expression and characterization of an insect class I glutathione S-transferase from Anopheles dirus species B. Ins. Biochem. Mol. Biol. 28:321-329.

91.Ranson, H., F. H. Collins, and J. Hemingway. 1998. The role of alternative mRNA splicing in generating heterogeneity within the Anopheles gambiae class I glutathione S-transferase family. Proc. Natl. Acad. Sci. USA 95:14284-14289.

92.Small, G. J., S. H. P. P. Karunaratne, and J. Hemingway. 1998. Characterization of amplified esterase EstB1 2 associated with organophosphate resistance in a multi- resistant population of the mosquito Culex quinquefasciatus (Diptera: Culicidae) from Cuba. Med. Vet. Entomol. 12:187-191.

93.Hemingway, J. 1999. Insecticide resistance in malaria vectors: A new approach to an old subject. Parassitologia 41:315-318.

94.Hemingway, J., J. Miller, and K. Y. Mumcuoglu. 1999. Pyrethroid resistance mechanisms in the head louse Pediculus capitis from Israel; implications for control. Med. Vet. Entomol. 13:89-96.

95.Hemingway, J., N. Hawkes, L. Prapanthadara, K. G. I. Jayawardena, and H. Ranson. 1999. The role of gene splicing, gene amplification and regulation in mosquito insecticide resistance. pp. 19-24 In I. Denholm, J. A. Pickett, and A. L. Devonshire [eds.], Insecticide Resistance: from Mechanisms to Management. CABI Publishing, Wallingford, Oxon.

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96.Hemingway, J., S. H. P. P. Karunaratne, and M. F. Claridge. 1999. Insecticide resistance spectrum and underlying resistance mechanisms in tropical populations of the brown planthopper ( Nilaparvata lugens ) collected from rice and wild grass Leersia hexandra . International Journal of Pest Management 45:215-223.

97.Karunaratne, S. H. P. P., G. J. Small, and J. Hemingway. 1999. Characterization of the elevated esterase-associated insecticide resistance mechanism in Nilaparvata lugens (Stal) and other planthopper species. International Journal of Pest Management 45:225-230.

98.Small, G. J., S. H. P. P. Karunaratne, D. D. Chadee, and J. Hemingway. 1999. Molecular and kinetic evidence for allelic variants of esterase Est1 in the mosquito Culex quinquefasciatus. Med. Vet. Entomol. 13:274-281.

99.Zaidi, R. H., Z. Jaal, N. Hawkes, J. Hemingway, and W. O. C. Symondson. 1999. Can multiple-copy sequences of prey DNA be detected amongst gut contents of invertebrate predators? Molecular Ecology 8:2081-2088.

100. Hemingway, J. 2000. The molecular basis of two contrasting mechanisms of insecticide resistance. Ins. Biochem. Mol. Biol. 30:1009-1015.

101. Hemingway, J., M. Coleman, M. G. Paton, L. McCarroll, A. Vaughan, and D. DeSilva. 2000. Aldehyde oxidase is coamplified with the world’s most common Culex mosquito insecticide resistance-associated esterases. Ins. Mol. Biol. 9:93-99.

102. Hemingway, J. and H. Ranson. 2000. Insecticide resistance in insect vectors of human disease. Ann. Rev. Ent. 45:369-389.

103. Karunaratne, S. H. P. P. and J. Hemingway. 2000. Insecticide resistance spectra and resistance mechanisms in populations of Japanese encephalitis vector mosquitoes, Culex tritaeniorhynchus and C. gelidus from Sri Lanka. Med. Vet. Entomol. 14:430-436.

104. Lee, C. Y., J. Hemingway, H. H. Yap, and N. L. Chong. 2000. Biochemical characterization of insecticide resistance in the German cockroach, Blattella germanica , from Malaysia. Med. Vet. Entomol. 14:11-18.

105. McCarroll, L., M. G. Paton, S. H. P. P. Karunaratne, H. T. R. Jayasuryia, K. S. P. Kalpage, and J. Hemingway. 2000. Insecticides and mosquito borne-disease. Nature 407:961-962.

106. Paton, M. G., S. H. P. P. Karunaratne, E. Giakoumaki, N. Roberts, and J. Hemingway. 2000. Quantitative analysis of gene amplification in insecticide resistant Culex mosquitoes. Biochem. J. 346:17-24.

107. Ranson, H., B. Jensen, J. M. Vulule, X. Xang, J. Hemingway, and F. H. Collins. 2000. Identification of a novel mutation in the voltage-gated sodium channel gene of Anopheles gambiae associated with resistance to pyrethroid insecticides. Ins. Mol. Biol. 9:491-497.

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108. Ranson, H., B. Jensen, X. Wang, L. Prapanthadara, J. Hemingway, and F. H. Collins. 2000. Genetic mapping of two loci affecting DDT resistance in the malaria vector, Anopheles gambiae . Insect Mol. Biol. 9:499-507.

109. Small, G. J. and J. Hemingway. 2000. Differential glycosylation produces heterogeneity in elevated esterases associated with insecticide resistance in the brown planthopper Nilaparvata lugens Stal. Ins. Biochem. Mol. Biol. 30:443-453.

110. Small, G. J. and J. Hemingway. 2000. Molecular characterisation of the amplified carboxylesterase gene associated with organophosphorous insecticide resistance in the brown planthopper, Nilaparvata lugens . Ins. Mol. Biol. 9:647-651.

111. Vontas, J. G., A. A. Enyati, G. J. Small, and J. Hemingway. 2000. A simple biochemical assay for glutathione S-transferase activity and its possible field application for insecticide resistance detection in single insects. Pest. Biochem. Physiol. 68:184-192.

112. Vontas, J. G., G. J. Small, and J. Hemingway. 2000. Comparison of insecticide resistance gene copy number, expression levels and esterase activity in insecticide susceptible and resistant Nilaparvata lugens (Stal). Insect Mol. Biol. 9:655-660.

113. Brooke, B. D., G. Kloke, L. L. Koekemoer, E. A. Temu, M. E. Taylor, G. J. Small, J. Hemingway, and M. Coetzee. 2001. Bioassay and biochemical analyses of insecticide resistance in southern African Anopheles funestus (Diptera: Culicidae). Bull. Ent. Res. 91:265-273.

114. Enayati, A. A., J. G. Vontas, G. J. Small, L. McCarroll, and J. Hemingway. 2001. Quantification of pyrethroid insecticides from treated bednets using a mosquito recombinant glutathione S-transferase. Med. Vet. Entomol. 15:58-63.

115. Karunaratne, S. H. P. P. and J. Hemingway. 2001. Malathion resistance and prevalence of the malathion carboxylesterase mechanism in populations of Sri Lankan mosquito vectors of disease. Bull. Wld Hlth Org. 79:1060-1064.

116. Molyneux, D. H., G. Barnish, S. Looreesuwan, B. Liese, and J. Hemingway. 2001. Malaria as a paradigm of an emergent disease. British Med. J. 323:571.

117. Roberts, P. H., X. Zhou, A. Holmes, H. Ranson, G. J. Small, J. Hemingway, J. D. Ng, L. Chen, and E. J. Meehan. 2001. Crystallization of agGST1-6, a recombinant glutathione S-transferasae from a DDT-resistant strain of Anopheles gambiae . Acta Cryst. D57:134-136.

118. Shamsi, F., L. McCarroll, J. Hemingway, and M. Boulton. 2001. Effect of lipofuscin on expression and activity of lysosomal enzymes in the retinal pigment epithelium. Free Radical Biology and Medicine 31:295-296.

119. Vontas, J. G., G. J. Small, and J. Hemingway. 2001. Glutathione S-transferases as antioxidant defence agents confer pyrethroid resistance in Nilaparvata lugens . Biochem. J. 357:65-72.

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120. Vontas, J. G., S. C. Tsakas, M. Loukas, and J. Hemingway. 2001. Low-activity allele of copper-zinc superoxide dismutase (CuZnSOD) in Drosophila increases paraquat genotoxicity but does not affect near UV radiation damage. Genome 44:597-601.

121. Vontas, J. G., N. Cosmidis, M. Loukas, S. Tsakas, M. J. Hejazi, A. Ayoutanti, and J. Hemingway. 2001. Altered acetylcholinesterase confers organophosphate resistance in the olive fruit fly Bacterocera oleae . Pestic. Biochem. Physiol. 71:124-132.

122. Alphey, L., B. Beard, P. F. Billingsley, M. Coetzee, A. Crisanti, C. F. Curtis, P. Eggleston, C. Godfray, J. Hemingway, M. Jacobs-Lorena, A. A. James, F. C. Kafatos, L. Mukwaya, M. G. Paton, J. R. Powell, W. R. Schneider, T. Scott, B. Sina, R. Sinden, S. P. Sinkins, A. Spielman, Y. T. Toure, and F. Collins. 2002. Malaria control with genetically manipulated insect vectors. Science 298:119-121.

123. Coleman, M., J. G. Vontas, and J. Hemingway. 2002. Molecular characterisation of the amplified aldehyde oxidase from insecticide resistant Culex quinquefasciatus . Eur. J. Biochem. 269:768-779.

124. DeSilva, D. and J. Hemingway. 2002. Structural organisation of the est31 gene in a Colombian strain of Culex quinquefasciatus differs from that in Cuba. Med. Vet. Entomol. 16:99-105.

125. Diabate, A., T. Baldet, F. Chandre, M. Akogbeto, F. Darriet, C. Brengues, T. R. Guiguemde, P. Guillet, J. Hemingway, G. J. Small, and J. M. Hougard. 2002. The role of agricultural use of insecticides in resistance to pyrethroids in Anopheles gambiae s.l. in Burkina faso. Am. J. Trop. Med. Hyg. 67:617-622.

126. Diabate, A., T. Baldet, F. Chandre, T. R. Guiguemde, P. Guillet, J. Hemingway, and J. M. Hougard. 2002. First report of the kdr mutation in Anopheles gambiae M form from Burkina Faso. Parassitologia 44:157-158.

127. Hawkes, N. J. and J. Hemingway. 2002. Analysis of the promoters for the -esterase genes associated with insecticide resistance in the mosquito Culex quinquefasciatus . Biochim. Biophys. Acta. 1574:51-62.

128. Hemingway, J., L. M. Field, and J. G. Vontas. 2002. Insecticide resistance and insect genomes. Science 298:96-97.

129. McCarroll, L. and J. Hemingway. 2002. Can insecticide resistance status affect parasite transmission in mosquitoes? Ins. Biochem. & Mol. Biol. 10:1345-1351.

130. Ranson, H., L. Rossiter, F. Ortelli, B. Jensen, X. Wang, C. W. Roth, F. H. Collins, and J. Hemingway. 2002. Identification of a novel class of insect glutathione S-transferases involved in resistance to DDT in the malaria vector Anopheles gambiae . Biochem. J. 359:295-304.

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131. Ranson, H., C. Claudianos, F. Ortelli, C. Abgrall, J. Hemingway, M. V. Sharakhova, M. F. Unger, F. H. Collins, and R. Feyereisen. 2002. Evolution of supergene families associated with insecticide resistance. Science 298:179-181.

132. Vontas, J. G., M. J. Hejazi, N. Hawkes, N. Cosmidis, M. Loukas, and J. Hemingway. 2002. Resistance associated point mutations of organophosphate insensitive acetylcholinesterase in the olive fruit fly Bactrocera oleae . Ins. Mol. Biol. 11:329-336.

133. Vontas, J. G., G. J. Small, D. Nikou, H. Ranson, and J. Hemingway. 2002. Purification, molecular cloning and heterologous expression of a glutathione S-transferase involved in insecticide resistance from the rice brown planthopper, Nilaparvata lugens . Biochem. J. 362:329-337.

134. Brengues, C., N. Hawkes, F. Chandre, L. McCarroll, S. Duchon, P. Guillet, S. Manguin, and J. Hemingway. 2003. Pyrethroid and DDT cross-resistance in Aedes aegypti is correlated with novel mutations in the voltage-gated sodium channel gene. Med. Vet. Entomol. 17:87-94.

135. Chen, L., P. H. Roberts, X. E. Zhou, H. Ranson, G. J. Small, J. Hemingway, and E. J. Meehan. 2003. Crystal structure of an insect class 1 glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae. Acta Cryst. D59:2211-2217.

136. Craig, A., S. Kyes, H. Ranson, and J. Hemingway. 2003. Malaria parasite and vector genomes: partners in crime. Trends in Parasitology 19:356-362.

137. Diabate, A., T. Baldet, F. Chandre, K. R. Dabire, P. Kengne, T. R. Guiguemde, S. Simard, P. Guillet, J. Hemingway, and J. M. Hougard. 2003. Kdr mutation, a genetic marker to assess events of introgression between the molecular M and S forms of Anopheles gambiae (Diptera: Culicidae) in the tropical savannah area of West Africa. J. Med. Ent. 40:195-198.

138. Diabate, A., T. Baldet, C. Brengues, P. Kengne, R. Dabire, F. Simard, F. Chandre, J. M. Hougard, J. Hemingway, J. B. Ouedrago, and D. Fontenille. 2003. Natural swarming behaviour in the molecular M form of Anopheles gambiae . Trans. Roy. Soc. Trop. Med. & Hyg. 97:1-4.

139. Ding, Y., F. Ortelli, L. Rossiter, J. Hemingway, and H. Ranson. 2003. The Anopheles gambiae glutathione transferase superfamily: annotation, phylogeny and expression profiles. BMC Genomics 4:35-45.

140. Enayati, A. A., H. Vatandoost, H. Townson, and J. Hemingway. 2003. Molecular evidence for a kdr -like pyrethroid resistance mechanism in Anopheles stephensi (Culicidae: Diptera). Med. Vet. Entomol. 17:138-144.

141. Hemingway, J. 2003. Insecticide resistance in insect vectors of human disease. pp. 80-88 In S. L. Knobler, S. M. Lemon, M. Najafi, and T. Burroughs [eds.], The resistance phenomenon in microbes and infectious disease vectors. Implications for

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human health and strategies for containment. Institute of Medicine of the National Academies, Washington D.C.

142. Hemingway, J. and I. Bates. 2003. Malaria past problems and future prospects. EMBO reports 4:29-31.

143. Nikou D, Ranson H, J. Hemingway. 2003. An adult-specific CYP6P450 gene is over expressed in a pyrethroid-resistant strain of the malaria vector, Anopheles gambiae . Gene 318: 91-102

144. Ortelli, F., L. Rossiter, J. G. Vontas, H. Ranson, and J. Hemingway. 2003. Heterologous expression of four glutathione S-transferase genes genetically linked to a major insecticide-resistance locus from the malaria vector Anopheles gambiae . Biochem J. 373:957-963.

145. Ranson, H. and J. Hemingway. 2003. Insect Pharmacology and Control: Glutathione transferases, In L. I. Gilbert, K. IATROU, and S. Gill [eds.], Comprehensive Insect Physiology, Biochemistry, Pharmacology and Molecular Biology. Elsevier B.V., Oxford.

146. Rodriguez, A. D., R. P. Penilla, M. H. Rodriguez, J. Hemingway, A. F. Betanzos, and J. E. Hernandez-Avila. 2003. Knowledge and beliefs about malaria transmission and practices for vector control in Southern Mexico. Salud Pub. Mexico 45:110-116.

147. Diabate A., Brengues C., Baldet T., Dabire K.R., Hougard J.M., Akogbeto M., Kengne P., Simard F., Guillet P., Hemingway J., F. Chandre 2004. The spread of the Leu-Phe kdr mutation through Anopheles gambiae complex in Burkina Faso: genetic introgression and de novo phenomena. Trop. Med. Int. Health 9: 1267-1273

148. Erlanger, T. E., A. A. Enayati, J. Hemingway, H. Mshinda, A. Tami, and C. Lengeler. 2004. Field issues related to the effectiveness of insecticide treated nets in Tanzania. Med. Vet. Entomol. 18:153-160.

149. Hemingway, J. 2004. The influence of genomics on the control of malaria and other vector borne diseases. South African Journal of Science 100:475-479.

150. Hemingway, J. 2004. Biological Control of Mosquitoes, pp. 649-660 Biology of Disease Vectors. Elsevier.

151. Hemingway, J. 2004. Taking aim at mosquitoes. Nature 430:936.

152. Hemingway, J. 2004. Control of insects and acarines, Biology of Disease Vectors. Elsevier.

153. Hemingway, J. and A. Craig. 2004. High- and low-tech malaria control. Science 304:1744.

154. Hemingway, J. and A. Craig. 2004. New ways to control malaria. Science 303:1984-1985.

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155. Hemingway J., Hawkes N.J., McCarroll L., H. Ranson. 2004. The molecular basis of insecticide resistance in mosquitoes. Ins. Biochem. Mol. Biol. 34: 653-665

156. Hemingway, J. and H. Ranson. 2004. Chemical control of vectors and mechanisms of resistance, pp. 627-637 Biology of Disease Vectors. Elsevier.

157. Ranson H., Paton M.G., Jensen B., McCarroll L., Vaughan A., Hogan J.R., Hemingway J., F.H. Collins. 2004. Genetic mapping of genes conferring permethrin resistance in the malaria vector, Anopheles gambiae. Ins. Mol. Biol. 13: 379-386

158. Vontas, J. G., L. McCarroll, S. H. P. P. Karunaratne, C. Louis, H. Hurd, and J. Hemingway. 2004. Does environmental stress affect insect-vectored parasite transmission? Phys. Entomol. 29:210-213.

159. David, J. P., C. Strode, J. G. Vontas, D. Nikou, A. Vaughan, P. M. Pignatelli, K. Louis, J. Hemingway, and H. Ranson. 2005. The Anopheles gambiae detoxification chip: a new highly specific microarray to study metabolic based insecticide resistance in malaria vectors. Proc. Natl. Acad. Sci. 102: 4080-4084.

160. Ding, Y., N. Hawkes, J. Meredith, P. Eggleston, J. Hemingway, and H. Ranson. 2005. Characterisation of the promoters of Epsilon glutathione transferases in the mosquito Anopheles gambiae and their response to oxidative stress. Biochem J. 387: 879-888.

161. Enayati, A. A., Ranson H., and Hemingway J. 2005. Insect glutathione transferases and insecticide resistance. Insect Mol. Biol. 14: 3-8.

162. Enayati A.A., Lengeler C., Erlanger T., Hemingway J. 2005. Field evaluation of a recombinant glutathione S-transferase-based pyrethroid quantification assay. Trans. Roy. Soc. Trop. Med. Hyg. 99: 369-378

163. Hawkes N.J., Janes R.W., Hemingway J., J.Vontas. 2005. Detection of resistance-associated point mutations of organophosphate-insensitive acetylcholinesterase in the olive fruit fly, Bactrocera oleae (Gmelin). Pest. Biochem. Physiol. 81: 154-163

164. Lumjuan N, McCarroll L, Prapanthadara LA, Hemingway J, H. Ranson. 2005. Elevated activity of an Epsilon class glutathione transferase confers DDT resistance in the dengue vector, Aedes aegypti. Ins. Biochem. Mol. Biol. 35: 861-871

165. Kelly-Hope, L. A., A. M. G. M. Yapabandara, M. B. Wickramasinghe, M. D. B. Perera, S. H. P. P. Karunaratne, W. P. Fernando, R. R. Abeyasinghe, R. Siyambalagoda, P. R. J. Herath, G. N. L. Galappaththy, and J. Hemingway. 2005. Spatiotemporal distribution of insecticide resistance in Anopheles culicifacies and Anopheles subpictus in Sri Lanka. Trans. Roy. Soc. Lond. Trop. Med. & Hyg. 99:751-761.

166. Lycett G., McLaughlin, L., Ranson, H., Hemingway J., Kafatos, F., Loukeris, T., and Paine, M. 2006. Anopheles gambiae P450 reductase is highly expressed in

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oenocytes and in vivo knockdown increases permethrin susceptibility. Insect mol. Biol. 15, 321 – 327.

167. Casimiro, S., Coleman, M., Mohloai, P., Hemingway, J. and Sharp, B. 2006. Insecticide resistance in Anopheles funestus from Mozambique. J. Med. Ent. 43, 267 – 275.

168. Casimiro, S., Coleman, M., Hemingway, J. and Sharp, B. 2006. Insecticide resistance in Anopheles gambiae and An. arabiensis from Mozambique. J. Med. Ent. 43, 276 – 282.

169. Coleman, M., Sharp, B., Seocharan, I. and Hemingway, J. 2006. Developing evidence based decision support system for rational insecticide choice in the control of the African malaria vectors. J. Med. Ent. 43, 663 – 668.

170. Hemingway, J., Beatty, B., Rowland, M., Scott, T.W. Sharp, B. 2006. The Innovative Vector Control Consortium: improved control of vector borne disease. Trends in Parasit. 22, 308 – 312.

171. Penilla, R.P., Rodriguez, A.D., Hemingway, J., Torres, J.L., Solis, F., and Rodriguez, M.H., 2006. Changes in glutathione S-transferase activity in DDT resistant natural populations of Anopheles albimanus under different insecticide resistance management strategies. Pest. Biochem. Physiol. 86, 63 – 71.

172. Rodriguez, A.D., Penilla, R.P., Rodriguez, M.H., Hemingway, J., Trejo, A., Hernandez-Avila, J.E., 2006. Accepta bility and perceived side effects of Indoor residual spraying under different insecticide resistance management strategies. Salud Publica de Mexico. 48, 317 – 324.

173. Thomas, D.R., McCarroll, L., Roberts R., Karunaratne, S.H., Roberts, C., Casey, D., Morgan, S., Touhig, K., Morgan, J., Collins, F., and Hemingway, J. 2006. Surveillance of insecticide resistance in head lice using biochemical and molecular methods. Arch. Dis. Childhood. 91, 777 – 778.

174. Casimiro, S., Hemingway, J., and Coleman, M. 2007. Operational impact of insecticide usage for malaria control against Anopheles funestus. Malaria Journal 6, 142

175. Coleman, M., and Hemingway, J. 2007. Insecticide resistance monitoring and evaluation in disease transmitting mosquitoes. J. Pest. Science 32, 69 – 76.

176. Enayati, A.A., Hemingway, J., and Garner, P. 2007. Electronic mosquito repellents for preventing mosquito bites and malaria infection. Cochrane Systematic Review 2, CD005434.

177. Penilla, R.P., Rodriguez, A.D., Hemingway, J., Trejo, A., and Lopez, A.D. 2007. Cytochrome P450 based resistance mechanism and pyrethroid resistance in

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Anopheles albimanus field resistance Management trial. Pest. Biochem. Physiol., 89, 111 – 117

178. Karunaratne, S.H., Damayanthi, B.T., Fareena, M.H.J., Imbuldeniya, V. and Hemingway, J. 2007. Insecticide resistance in the tropical bedbug Cimex hemipterus . Pest. Biochem. Physiol. 88, 102 – 107.

179. Karunaratne, S.H., Hawkes, N.J., Perera, M.D.B., Ranson, H., and Hemingway, J. 2007. Mutated sodium channel genes and elevated monooxygenases are found in pyrethroid resistant populations of Sri Lankan malaria vectors. Pest. Biochem. Physiol. 88, 108 – 113.

180. Saavedra-Rodriguez, K., Urdaneta-Marquez, L., Rajatileka, S., Moulton, M., Flores, A.E., Fernandez-Salas, I., Bisset, RJ., Rodriguez, M., McCall, P.J., Donnelly, M.J., Ranson, H., Hemingway, J., and Black, W.C. 2007. A mutation in the voltage gated sodium channel genes associated with pyrethroid resistance in Latin American Aedes aegypti . Insect Mol. Biol. 16, 785 – 798.

181. Strode, C., Djouaka, R.F., Bakare, A.A., Akogbeto, M., and Hemingway, J. 2007. Evidence for metabolic resistance in pyrethroid resistant populations of Anopheles gambiae from Benin, West Africa. American J. Trop. Med. Hyg. 77, 177 – 178.

182. Vontas, J., David J.P., Nikou, D., Hemingway, J., Christophedes, G.K., Louis, C. Ranson, H. 2007. Transcriptional analysis of insecticide resistance in Anopheles stephensi using cross-species microarray hybridisation. Insect Mol. Biol. 16, 315 – 324.

183. Wondji, C.S., Hemingway, J., Ranson, H. 2007. Identification and analysis of single nucleotide polymorphisms (SNPs) in the mosquito Anopheles funestus malaria vector. BMC Genomics 8, Article 5.

184. Wondji, C.S., Morgan, J., Coetzee, M., Hunt, R.H., Steen, K., Black, W.C., Hemingway, J., and Ranson, H. 2007. Mapping a quantitative trait loci conferring pyrethroid resistance in the moAfrican malaria vector Anopheles funestus . BMC Genomics 8, article 34.

185. Adasi K and Hemingway J, 2008. Susceptibility to three pyrethroids and detection of knockdown resistance mutation in Ghanaian Anopheles gambiae sensu stricto Journal of Vector Ecology    33    : 255-262  

   186. Axarli, I.A., Kapoli, P., Platis, D., Fragulaki, M., Paine, M.J.I., Hemingway, J.,

Vontas, J. and Labrou, N. 2008. Engineering sensitive glutathione transferase for the detection of xenobiotics. Biosensors and bioelectronics. 24: 498 – 504.

187. Casimiro, S. L., Hemingway, J., Sharp, B.L., Coleman, M., 2008. Monitoring and operational impact of insecticide usage for malaria control on Anopheles funestus from Mozambique. Malaria Journal 7, 8.

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188. Coleman M, Casimiro S, Hemingway J, Sharp B, 2008. Monitoring the operational impact of insecticide usage for malaria control on Anopheles funestus from Mozambique. American Journal of Tropical Medicine and Hygiene     79:        69  

189. Coleman M, Morris N, Kleinschimidt I, Maharaj R, Hemingway J, 2008. Malaria decision support systems - lessons learnt. American Journal of Tropical Medicine and Hygiene    79    : 140

190. Djouaka R. F., Bakare A. A., Coulibaly O. N, Akogbeto M. C., Ranson H., Hemingway J. and Strode C. 2008 Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria. BMC Genomics 2008, 9:538

191. Kelly-Hope, L., Ranson, H. and Hemingway, J. 2008. Lessons from the past: managing insecticide resistance in malaria control and eradication programmes. Lancet Inf. Dis. 8, 387 – 389.

192. McLaughlin, L.A., Niazi, U., Bibby, J., David, J.P., Vontas, J., Hemingway, J., Ranson, H., Sutcliffe, M.J. and Paine, M.J. 2008. Characterization of inhibitors and substrates of Anopheles gambiae CYP6Z2. Insect Mol. Biol. 17, 125 – 135.

193. Morou E, Ismail HM, Dowd AJ, Hemingway J, Labrou N Paine M, Vontas J., 2008 A dehydrochlorinase-based pH change assay for determination of DDT in sprayed surfaces. Analyt. Biochem., 378, 60 – 64

194. Muller, P., Warr, E., Stevenson, B.J., Pignatelli, P.M., Morgan J.C., Steven A., Yawson, A.E., Mitchell, S.N., Ranson, H., Hemingway, J., Paine, and M.J., Donnelly, M.J., 2008. Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids. PLoS Genetics 4 (11).e1000286.doi:10.1371/journal.pgen.1000286.

195. Oxborough RM , Mosha FW, Matowo J, Mndeme R, Feston E, Hemingway J and Rowland M 2008. Mosquitoes and bednets: testing the spatial positioning of insecticide on nets and the rationale behind combination insecticide treatments Annals of Tropical Medicine and Parasitology     102     717-727      

196. Perera, M.D., Hemingway, J., and Karunaratne, S.H.P.P. 2008. Multiple insecticide

resistance mechanisms involving metabolic changes and insensitive target sites selected in anopheline vectors of malaria from Sri Lanka. Malaria J. 7, 168 (10 pages)

197. Shamsi FA, McCarroll L, Hemingway J, 2008 Effect of age pigment lipofuscin on the expression of lysosomal and antioxidant enzymes in the RPE cells. FEBS J. 275, 429-430  

198. Strode, C., Wondji, C.S., David, J.P., Hawkes, N.J., Lumjan, N., Nelson, D.R., Drane, D.R., Karunaratne, S.H., Hemingway, J., Black, W.C. and Ranson, H.

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2008. Genomic analysis of detoxification genes in the mosquito Aedes aegypti . Insect Biochem. Mol. Biol. 38, 113 – 123.

199. Wondji CS, De Silva WAPP, Hemingway J, 2008. , Characterization of knockdown resistance in DDT- and pyrethroid-resistant Culex quinquefasciatus populations from Sri Lanka. Trop. Med. Int. Health 13, 548 – 555.

200. Dowd AJ, Steven A, Morou E, Hemingway J, Vontas J, Paine MJI 2009. A simple glutathione transferase-based colorimetric endpoint assay for insecticide detection ENZYME AND MICROBIAL TECHNOLOGY  45  164-168  

201. Enayati A, Asgarian F, Amouei A, Hemingway J 2009 The first report of two Ornithodoros tick species, the main vectors of relapsing fever from North of Iran, and a review of the disease situation in the country TROPICAL MEDICINE & INTERNATIONAL HEALTH   14   222-228

202. Enayati AA, Asgarian F, Sharif M, Boujhmehrani H, Amouei A, Vahedi N, Boudaghi B, Piazak N, Hemingway J 2009 Propetamphos resistance in Rhipicephalus burs a (Acari, Ixodidae) . VETERINARY PARASITOLOGY     162     135-141  

 203. Kelly-Hope L A, Hemingway J and McKenzie F E 2009 Environmental factors

associated with the malaria vectors Anopheles gambiae and Anopheles funestus in Kenya Malaria Journal, 8:268

204. Penilla R. P, Ranson H, Padilla N, Morgan J C., Steen K, Pignatelli P, Rodríguez A D., Hemingway J, Brogdon W G., Black, IV W C., AND Benedict M Q. * 2009 Towards a Genetic Map for Anopheles albimanus : Identification of Microsatellite Markers and a Preliminary Linkage Map for Chromosome 2. Am. J. Trop. Med. Hyg., 81(6) 1007-1012

205. Ponce García G, Flores A E., Fernández-Salas I, Saavedra-Rodríguez K, Reyes-Solis G, Lozano-Fuentes S, Bond J. G, Casas-Martínez M, Ramsey J M., García-Rejón J, Domínguez-Galera M, Ranson H, Hemingway J, Eisen L, Black IV W C.,

2009 Recent Rapid Rise of a Permethrin Knock Down Resistance Allele in Aedes aegypti in México PLOS NEGLECTED TROPICAL DISEASES  : 3   : e531

   206. Singh Om P., Bali, Prerna, Hemingway J, Subbarao SK , Dash AP, Adak T.

2009 PCR- based methods for the detection of L1014 kdr mutation in Anopheles culicifacies sensu lato MALARIA JOURNAL 8 154,  Source: MALARIA JOURNAL Volume: 8   Article Number: 154

207. Torgett G, Alonso P, Binka F, Collins F, Greenwood B, Hemingway J, ter Kuile F, Sankoh O, Schellenberg D. 2009 Global health and the Bill & Melinda Gates Foundation LANCET   373  2195-2195    

208. Wondji CS, Irving H, Morgan J, Lobo NF , Collins FH, Hunt RH, Coetzee M, Hemingway J and Ranson H. 2009. Two duplicated P450 genes are associated

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with pyrethroid resistance in Anopheles funestus, a major malaria vector Genome Research 19 : 452-459  

209. Koudou GB, Hemingway J. Nov 2009. MONITOR AND OPTIMIZE DURABLY THE USAGE OF INSECTICIDE TREATED NETS WITHIN HOUSEHOLDS WITH DETECTOR FOR REDUCING MALARIA TRANSMISSION, IN CENTRAL IVORY COAST: RESULTS OF PRELIMINARY TRIALS Source: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE    Volume: 81    Issue: 5    Pages: 170-170    Supplement: Suppl. S    Meeting Abstract: 597  

210. Saavedra-Rodriguez K, Strode C, Reyes-Solis G, Flores-Suarez A, Ranson H, Hemingway J, Black W. Nov 2009. CHANGES IN THE TRANSCRIPTION OF DETOXIFICATION GENES IN RESPONSE TO SELECTION WITH TEMEPHOS AND PERMETHRIN IN AEDES AEGYPTI Source: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE    Volume: 81 Issue: 5    Pages: 315-315    Supplement: Suppl. S    Meeting Abstract: 1091   

211. Enayati A, Hemingway J 2010. Malaria Management: Past, Present, and Future. ANNUAL REVIEW OF ENTOMOLOGY: 55: 569-591   

212. Koudou, B. G., Janmohamed, N., Tschannen, A. B. Tanner, M., Hemingway, J., Utzinger J. 2010. Effects of seasonality and irrigation on malaria transmission in two villages in Cote d'Ivoire. ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY   104   : 109-121   

213. Hay, Simon I., Sinka, Marianne E., Okara, Robi M., Kabaria, Caroline W., Mbithi, Philip M., Tago, Carolynn C., Benz, David, Gething, Peter W., Howes, Rosalind E., Patil, Anand P., Temperley, William H., Bangs, Michael J., Chareonviriyaphap, Theeraphap, Elyazar, Iqbal R. F., Harbach, Ralph E., Hemingway, Janet, Manguin, Sylvie., Mbogo, Charles M., Rubio-Palis, Yasmin, Godfray, H. Charles J. 2010. Developing Global Maps of the Dominant Anopheles Vectors of Human Malaria. PLOS MEDICINE    7   : e1000209   

214. Morou E, Dowd AJ, Rajatileka S, Steven A, Hemingway J, et al. 2010. A Simple Colorimetric Assay for Specific Detection of Glutathione-S Transferase Activity Associated with DDT Resistance in Mosquitoes. PLoS Negl Trop Dis 4(8): e808. doi:10.1371/journal.pntd.0000808

215. Dowd AJ, Morou E, Steven A, Ismail HM, Labrou N, Hemingway J, Paine MJI, Vontas J 2010. Development of a colourimetric pH assay for the quantification of pyrethroids based on glutathione-S-transferase. INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY    Volume: 90 Issue: 12 Pages: 922-933

216. Enayati, A. A.; Asgarian, F.; Amouei, A.; Sharif, M.; Mortazavi, H.; Boujhmehrani, H.; Hemingway, J. 2010. Pyrethroid insecticide resistance in Rhipicephalus bursa (Acari, Ixodidae): Pesticide Biochemistry and Physiology Volume: 97 Issue: 3 Pages: 243-248

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217. Peter Arensburger, Karine Megy, Robert M. Waterhouse, Jenica Abrudan, Paolo Amedeo, Beatriz Antelo, Lyric Bartholomay, Shelby Bidwell, Elisabet Caler, Francisco Camara, Corey L. Campbell, Kathryn S. Campbell, Claudio Casola, Marta T. Castro, Ishwar Chandramouliswaran, Sinéad B. Chapman, Scott Christley, Javier Costas, Eric Eisenstadt, Cedric Feschotte, Claire Fraser-Liggett, Roderic Guigo, Brian Haas, Martin Hammond, Bill S. Hansson, Janet Hemingway, Sharon R. Hill, Clint Howarth, Rickard Ignell, Ryan C. Kennedy, Chinnappa D. Kodira, Neil F. Lobo, Chunhong Mao, George Mayhew, KristinMichel, Akio Mori, Nannan Liu, Horacio Naveira, Vishvanath Nene, NamNguyen, Matthew D. Pearson, Ellen J. Pritham, Daniela Puiu, Yumin Qi, Hilary Ranson, Jose M. C. Ribeiro, Hugh M. Roberston, David W. Severson, Martin Shumway, Mario Stanke, Robert L. Strausberg, Cheng Sun, Granger Sutton, Zhijian (Jake) Tu, Jose Manuel C. Tubio, Maria F. Unger, Dana L. Vanlandingham, Albert J. Vilella, Owen White, Jared R. White, Charles S. Wondji, Jennifer Wortman, Evgeny M. Zdobnov, Bruce Birren, Bruce M. Christensen, Frank H. Collins, Anthony Cornel, George Dimopoulos, Linda I. Hannick, Stephen Higgs, Gregory C. Lanzaro, Daniel Lawson, Norman H. Lee, Marc A. T. Muskavitch, Alexander S. Raikhel, Peter W. Atkinson. 2010. Sequencing of Culex quinquefasciatus establishes a platform for mosquito comparative genomics. Science (New York, N.Y.) 330(6000):86-8, 2010 Oct 1

218. Lyric C. Bartholomay, Robert M. Waterhouse, George F. Mayhew, Corey L. Campbell, Kristin Michel, Zhen Zou, Jose L. Ramirez, Suchismita Das, Kanwal Alvarez, Peter Arensburger, Bart Bryant, Sinead B. Chapman, Yuemei Dong, Sara M. Erickson, S. H. P. Parakrama Karunaratne, Vladimir Kokoza, Chinnappa D. Kodira, Patricia Pignatelli, Sang Woon Shin, Dana L. Vanlandingham, Peter W. Atkinson, Bruce Birren, George K. Christophides, Rollie J. Clem, Janet Hemingway, Stephen Higgs, Karine Megy, Hilary Ranson, Evgeny M. Zdobnov, Alexander S. Raikhel, Bruce M. Christensen, George Dimopoulos, Marc A. T. Muskavitch. 2010 Pathogenomics of Culex quinquefasciatus and meta-analysis of infection responses to diverse pathogens. Science 1 October 2010: Vol. 330. no. 6000, pp. 88 – 90

219. Bradley J. Stevenson, Jaclyn Bibby, Patricia Pignatelli, Sant Muangnoicharoen, Paul M. O’Neill, Lu-Yun Lian, Pie Müller, Dimitra Nikou, Andrew Steven, Janet Hemingway, Michael J. Sutcliffe, Mark J.I. Paine. 2011. Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed  Original Research Article Insect Biochemistry and Molecular Biology, Volume 41, Issue 7, July 2011, Pages 492-502

220. Michalak, Pawel, Gregory, Richard, Darby, Alistair C., Irving, Helen, Coulibaly, Mamadou B., Hughes, Margaret, Koekemoer, Lizette L., Coetzee, Maureen, Ranson, Hilary, Hemingway, Janet, Hall, Neil and Wondji, Charles S. 2011. A De Novo Expression Profiling of Anopheles funestus , Malaria Vector in Africa, Using 454 Pyrosequencing . PLoS ONE, Vol 6, Issue 2, e17418

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221. Abilio, Ana P., Kleinschmidt, Immo, Rehman, Andrea M., Cuamba, Nelson, Ramdeen, Varsha, Mthembu, David S., Coetzer, Sarel, Maharaj, Rajendra, Wilding, Craig S., Steven, Andrew, Coleman, Marlize, Hemingway, Janet and Coleman, Michael. 2011. The emergence of insecticide resistance in central Mozambique and potential threat to the successful indoor residual spraying malaria control programme . Malaria Journal, Vol 10, Issue 1, p. 110.

222. Koudou, Benjamin, Koffie, Alphonsine, Malone, David and Hemingway, Janet. 2011. Efficacy of PermaNet® 2.0 and PermaNet® 3.0 against insecticide-resistant Anopheles gambiae in experimental huts in Côte d’Ivoire . Malaria Journal, Vol 10.

223. Emmanuel Chanda, Janet Hemingway, Immo Kleinschmidt, Andrea M. Rehman, Varsha Ramdeen,Faustina N. Phiri, Sarel Coetzer, David Mthembu, Cecilia J. Shinondo, Elizabeth Chizema-Kawesha, Mulakwa Kamuliwo, Victor Mukonka, Kumar S. Baboo, Michael Coleman 2011 Insecticide Resistance and the Future of Malaria Control in Zambia, . PLoS ONE 6(9): e24336. doi:10.1371/journal.pone.0024336 224 Published: September 6, 2011

224. Saavedra-Rodriguez, K (Saavedra-Rodriguez, K.); Suarez, AF (Suarez, A. F.); Salas, IF (Salas, I. F.); Strode, C (Strode, C.); Ranson, H (Ranson, H.); Hemingway, J (Hemingway, J.); Black, WC (Black, W. C.) Transcription of detoxification genes after permethrin selection in the mosquito Aedes aegypti. INSECT MOLECULAR BIOLOGY  Volume: 21  Issue: 1  Pages: 61-77  DOI: 10.1111/j.1365-2583.2011.01113.x  Published: FEB 2012 . ISSN: 0962-1075

225. Mitchell, SN; Stevenson, BJ; Muller, P; Wilding, CS; Egyir-Yawson, A; Field, SG Hemingway, J; Paine, MJI; Ranson, H; Donnelly, MJ; Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  Volume: 109  Issue: 16  Pages: 6147-6152  DOI: 10.1073/pnas.1203452109  Published: APR 17 2012. ISSN: 0027-8424

226. Giancarlo A. Biagini, Nicholas Fisher, Alison E. Shone, Murad A. Mubaraki, Abhishek Srivastava, Alisdair Hill, Thomas Antoine, Ashley J. Warman, Jill Davies, Chandrakala Pidathala, Richard K. Amewu, Suet C. Leung, Raman Sharma, Peter Gibbons, David W. Hong, Bénédicte Pacorel, Alexandre S. Lawrenson, Sitthivut Charoensutthivarakul, Lee Taylor, Olivier Berger, Alison Mbekeani, Paul A. Stocks, Gemma L. Nixon, James Chadwick, Janet Hemingway, Michael J. Delves, Robert E. Sinden, Anne-Marie Zeeman, Clemens H. M. Kocken, Neil G. Berry, Paul M. O’Neill, and Stephen A. WardGeneration of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria PNAS 2012 109 (21) 8298-8303; published ahead of print May 7, 2012, doi:10.1073/pnas.1205651109

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227. Charles S. Wondji, Michael Coleman, Immo Kleinschmidt, Themba Mzilahowa, Helen Irving, Miranda Ndula, Andrea Rehman, John Morgan, Kayla G. Barnes, and Janet Hemingway

Inaugural Article: Impact of pyrethroid resistance on operational malaria control in Malawi PNAS 2012 109 (47) 19063-19070; published ahead of print November 1, 2012, doi:10.1073/pnas.1217229109

228. Chanda E, Coleman M, Kleinschmidt I, Hemingway J, Hamainza B, Masaninga F, Chanda-Kapata P, Baboo KS, Dürrheim DN, Coleman M.

Impact assessment of malaria vector control using routine surveillance data in Zambia: implications for monitoring and evaluation. Malar J. 2012 Dec 29;11:437. doi: 10.1186/1475-2875-11-437.

229. Hemingway J, Vontas J, Poupardin R, Raman J, Lines J, Schwabe C, Matias A, Country-level operational implementation of the Global Plan for Insecticide Resistance Management. I.Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9397-402. doi: 10.1073/pnas.1307656110. Epub 2013 May 21.

230. Ismail HM, O'Neill PM, Hong DW, Finn RD, Henderson CJ, Wright AT, Cravatt BF, Hemingway J, Paine MJ.Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19766-71. doi: 10.1073/pnas.1320185110. Epub 2013 Nov 18.

231. Riveron JM, Yunta C, Ibrahim SS, Djouaka R, Irving H, Menze BD, Ismail HM, Hemingway J, Ranson H, Albert A, Wondji CS.A single mutation in the GSTe2 gene allows tracking of metabolically-based resistance in a major malaria vector. Genome Biol. 2014 Feb 25;15(2):R27.

232. Koudou BG, Malone D, Hemingway JThe use of motion detectors to estimate net usage by householders, in relation to mosquito density in central Cote d'Ivoire: preliminary results. Parasit Vectors. 2014 Mar 6;7:96. doi: 10.1186/1756-3305-7-96

233. Strode C, Donegan S, Garner P, Enayati AA, Hemingway J.The impact of pyrethroid resistance on the efficacy of insecticide-treated nets against African anopheline mosquitoes: systematic review and meta-analysis. PLoS Med. 2014 Mar 18;11(3):e1001619. doi: 10.1371/journal.pmed.1001619. eCollection 2014 Mar

234. Vontas J, Moore S, Kleinschmidt I, Ranson H, Lindsay S, Lengeler C, Hamon N,T, Hemingway J.

Framework for rapid assessment and adoption of new vector control tools. Trends Parasitol. 2014 Apr;30(4):191-204. doi: 10.1016/j.pt.2014.02.005. Epub 2014 Mar

235. Hemingway J.The role of vector control in stopping the transmission of malaria: threats and opportunities. Philos Trans R Soc Lond B Biol Sci. 2014 May

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12;369(1645):20130431. doi: 10.1098/rstb.2013.0431. Print 2014.

236. Russell TL, Morgan JC, Ismail H, Kaur H, Eggelte T, Oladepo F, Amon J, Hemingway J, Iata H, Paine MJEvaluating the feasibility of using insecticide quantification kits (IQK) for estimating cyanopyrethroid levels for indoor residual spraying in Vanuatu. Malar J. 2014 May 9;13:178. doi: 10.1186/1475-2875-13-178

237. Thomsen EK, Strode C, Hemmings K, Hughes AJ, Chanda E, Musapa M, Kamuliwo M, Phiri FN, Muzia L, Chanda J, Kandyata A, Chirwa B, Poer K, Hemingway J, Wondji CS, Ranson H, Coleman M.Underpinning Sustainable Vector Control through Informed Insecticide Resistance Management. PLoS One. 2014 Jun 16;9(6):e99822. doi: 10.1371/journal.pone.0099822. eCollection 2014

238. Coleman M, Al-Zahrani MH, Coleman M, Hemingway J, Omar A, Stanton MC, Thomsen EK, Alsheikh AA, Alhakeem RF, McCall PJ, Al Rabeeah AA, Memish ZA.A country on the verge of malaria elimination--the Kingdom of Saudi Arabia. PLoS One. 2014 Sep 24;9(9):e105980. doi: 10.1371/journal.pone.0105980. eCollection 2014. PMID: 25250619

239.

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