DNA

DNA

DNA

Recombinant DNA Technology

DNA

DNA

DNADNA

DNA

PCRPCR

DNAPCR

(Gene deletion, replacement, site directed mutagenesis)

(Genetically modified organisms)

DNA

1- T. Primrose and J. Old, Principle of Gene Manipulation . Blackwell sciences publication, 2001.

2- S. Desmond and T. Nicholl, An introduction to Genetic Engineering . Cambridge University Press, 2002.

3- T. A. Brown, Genome . Bios Scientific Publishers Ltd, 2002. 4- Kreuzer H. and Massey A, Recombinant DNA and Biotechnology . 2nd ed. ASM Publication,

2001.

Advanced Molecular Genetics 1

(DNA rearrengement) DNA

(Mating type switching)

DNA

1. B. Lewin, Genes VIII . Oxford Press, 2003. 2. M. L. Depampilis, Concepts in eucaryotic DNA replication . Cold Spring Harbor

Laboratory, 1998. 3. J. D. Watson, Molecular biology of the gene . The Benjamin/Cummings Company, Inc,

2004. 4. H. Lodish, Molecular cell biology . Freeman Publisher, 2003.

Advanced Molecular Genetics 2

RNA

RNA

(Post-transcriptional regulation)

(RNA splicing)

(RNA editing) RNA

mRNA

1. B. Lewin, Genes VII . Oxford University Press, 2003. 2. J. Locker, Transcription Factors . Academic Press, 2000. 3. J. D. Watson, Molecular biology of the gene . The Benjamin/Cummings Company,

Inc, 2004.

Molecular Bases of Genetic Diseases

1) T. Strachan and A.P.Read. "Human molecular genetics" Garland Science, 2004. 2) R. L., Nussbaum, McInnes R. R. and Willard H. F. Thompson and Thompson, Genetics in

medicine . W. B. Saunders company Toronto, 2001. 2) J. J. Pasternak, An introduction to human molecular genetics: mechanisms of inherited

diseases . Fitzgerald Science Press, USA, 1999.

Oncogenes

DNA

DNA microarray

1- G. M. Cooper, Oncogenes . Jones and Bartlett Publishers, 2002. 2- J. K. Cowell, Molecular genetics of cancer . Bios Scientific, 2002.

DNARecombination and DNA Repair

DNA

DNA

DNADNA

DNA

DNA

ADPPoly (ADP-ribose) PolymeraseDNA

Ageing

- -

1- A. Nickoloff and Hoekstra M. F. DNA damage and repair . Vol.1, DNA repair in prokaryotes and lower eukaryotes. Humana Press, Totowa, New Jersey, 1998.

2- A. Nickoloff and Hoekstra M. F. DNA damage and repair . Vol. 2, DNA repair in higher eukaryotes. Humana Press, Totowa, New Jersey, 1998.

3- E. C. Friedberg, DNA repair and mutagenesis . ASM Press, Washington, DC, 1995. 4- D. S. Henderson, DNA repair protocols , eukaryotic systems. Humana Press. Totowa, New

Jersey, 1999. 5- T. Lindahl and West S. C. DNA repair and recombination . Chapman and Hall, London,

1995.

Advanced Molecular Biology

Signaling(Development)

(Protein-Targeting)

(Chaparones)

(Targeting)

ER

- -

1. H. Lodish, Molecular cell Biology . Freeman Publisher, 2003. 2. B. Gomperts, Signal transduction . Academic Press, 2002.

Genetics of Microorganisms

Global ControlPleiotrophic

Transposition

(Bacteriophage)

- -

1- U. N. Streips and Yasbin R. E. Modern microbial genetics , John Wiley and Sons, 2002. 2- J. A. Christopher and Edward D. B. Genetically Engineered viruses . Bois Seientific, 2001.

Advanced Techniques

PCR

(Microarray)

DNA

DNA

DNA

CHEF

1. L. Davis, Kuehl M. and Battey J. Basic methods in molecular biology . 2nd Ed. Appleton and Lange, 1994.

2. R. I. Freshney, Culture of animal cells, a manual of basic techniques . 3rd Ed. John Wiley & Sons, Inc, 1999.

Biochemistry of Chromatin

DNA

(Nucleoskeleton)

Nuclear lamina

Nuclear matrix

Core filaments

NucleoluskeletonrDNA

Silencing proteins

rDNA

1- B.M.Turner, Chromatin and gene regulation, Mechanisms in epigenetics . Blackwell Science Ltd, 2001.

2- R. V. Drieb and Otte A.P., Nuclear organization, chromatin structure, and gene expression . Oxford University Press Inc, 1997.

3- S.C.R. Elgin, Chromatin structure and gene expression . Oxford University Press Inc, 1997.

Genetic Updates

RNAisiRNA

1- www.ncbi.nlm.nih.gov. 2- www.hmg.oupjournals.org

3- www4.infotrieve.com/newmedline/search.asp

Quantitative Genetics

Metric character

Heritability

1. D. S. Falconer, Introduction to quantitative genetics . 3rd edition. Longman Scientfic and Technical, 1989.

2. S. K. Manjit, Quantitative genetics, genomics and plant breeding . Oxford University Press, 2002.

3. B. Lewin, Genes VIII . Oxford Press, 2003.

Advanced Bioinformatics

1- A. D. Baxevanis and Francis O. B. F. Bioinformatics , John Wiley & Sons, 2001. 2- D. M. Webster, Protein structure Prediction . Humana Press, 2000.

Cytogenetics

(FISH)(SKY)

(CGH)

1- R. L. Nussbaum, R. R. McInnes, H. F. Willard, Thompson and Thompson. Genetics in Medicine . W. B. Sannders Company, 2004.

2- D. E. Rooney and Czepulkowski B. H., Human chromosome preparation , Essential techniques. John Wiley and Sons, 1997.

Advanced Population Genetics

- -

1) D. A. Hartl and Clark A. G. Principles of population Genetics . Sinecure Associates, Inc, 1997.

2) D. L. Hartl. A primer of population Genetics . Sinecure Associates, Inc, 2000.

Advanced Statistical Biology --

1) Principles and procedures of Statistics (A Biometrical Approach) Robert G. D. Steel and James H. Torrie.

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