dna history,structure,and
DESCRIPTION
DNA History,Structure,and. Check out Griffith’s experiment on page 138. What is up? Shows how harmless bacteria can turn deadly. How? DNA is transferred!. DNA (de-oxy-ribo-nucleic acid) a nucleic acid that stores and transmits the genetic information from one generation to the next. - PowerPoint PPT PresentationTRANSCRIPT
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DNAHistory,Structure,and
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Check out Griffith’s experiment on page 138
• What is up?• Shows how harmless bacteria can
turn deadly.• How? DNA is transferred!
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DNA(de-oxy-ribo-nucleic acid)a nucleic acid that stores and transmits the genetic
information from one generation to the next
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Big Players in DNA• Chargaff• Rosalind Franklin• Watson and Crick
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People knew that DNA was made up of:
•Adenine (A)•Guanine (G)•Cytosine (C)•Thymine (T)
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Erwin Chargaff• Discovered that in any
sample of DNA, the amount of A equals the amount of T and the amount of C equals the amount of G.
• This suggested that A binds with T and that C binds with G.
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Rosalind Franklin’sX-Ray Crystallography
• Took x-ray photographs of crystallized DNA
• Discovered that the shape of DNA must be a helix, because of the x-ray pattern
• Died of cancer (too many x-rays?)
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An example of X-Ray Crystallography
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Watson and Crick• Credited for
discovering the structure of DNA in 1953
• Used Chargaff and Franklin’s discoveries along with toy models to discover the structure
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A 3-D Model of DNA
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NUCLEOTIDESMade up of:• A phosphate group• 5 carbon sugar• Nitrogenous Base
(nitrogen containing)
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PURINES•Adenine (A)•Guanine (G)
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PYRIMIDINES•Cytosine (C)•Thymine (T)
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Base Pairing in DNAA-T C-G
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Guanine Nucleotide
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Write the complementary DNA strand for each of these DNA
strands:DNA
• GAATTACA• CCAATTAG• ATAGACAG• CCAGTACA
DNA• CTTAATGT• GGTTAATC• TATCTGTC• GGTCATGT
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Examples of DNA Replication