dna fingerprinting
DESCRIPTION
DNA FINGERPRINTING. The story…. 1) Provide a timeline 2) Draw a family tree 3) How could you explain Tom’s resemblance to TJ? 4) Why is the Y chromosome a good marker? 5) What is a haplotype ? 6)How can the descendants be used to indicate paternity?. DNA. Double helix A = T C = G. - PowerPoint PPT PresentationTRANSCRIPT
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DNA FINGERPRINTING
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The story…The story…
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1) Provide a timeline1) Provide a timeline
2) Draw a family tree2) Draw a family tree
3) How could you explain Tom’s 3) How could you explain Tom’s resemblance to TJ?resemblance to TJ?
4) Why is the Y chromosome a good 4) Why is the Y chromosome a good marker?marker?
5) What is a haplotype?5) What is a haplotype?
6)How can the descendants be used to 6)How can the descendants be used to indicate paternity?indicate paternity?
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DNA
• Double helix
• A = T C = G
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Restriction Enzymes
• Bacterial origin• Cuts DNA sequences into shorter fragments• Site specific
Ex: EcoR1 cuts at GAATTC sequence
different DNA sequences
Living organisms that have different characteristics
The more different the organisms
the more different are the DNA sequences
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Restriction EnzymesRestriction Enzymes
www.uic.edu/classes/phar/phar331/lecture6/
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DNA FINGERPRINTINGDNA FINGERPRINTING
http://www.biotech.iastate.edu/biotech_info_series/bio6.html#anchor861530#anchor861530
Professor Sir Alec Jeffreys
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DNA Fingerprinting-DNA Fingerprinting-
Who’s the father?
Are you sure?
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Use Multiple Probes
Eric S. Lander
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An Meeker-O'Connell