dissertaion
TRANSCRIPT
THE CREATION OF ANTIBACTERIAL FIBRES
JOSEFIN ILLERGÅRD
10x
vs
Ag+
TWO REASONS
0,00 0,50 1,00 1,50
Göteborg
Lysekil
Uddevalla
TRICLOSAN (µg/L)
ANTIBACTERIAL
SURFACES
CONTACT-ACTIVE
VS
LEACHING
LEACHING
COMMON
UNWANTED
THE BACTERIA
HYDROPHOBICITY EFFECT 50 nm
Figure Tiller et al 2001
INFLUENCE OF CHARGE
Figure from Murata et al 2007
CHARGE
+ WELL-DESCRIBED
- ORGANIC SOLVENTS
- HARSH CONDITIONS
POLYELECTROLYTE MULTILAYERS
+ WATER BASED
+ SIMPLE
- ?
POLYVINYLAMINE
Model surface
0
5
10
15
20
25
0 10 20 30 40 50 60 70
Sauerb
rey m
ass (
mg/m
2)
100 mM
10 mM
1 mM
QCM-D
FLAT & DENSE
HYDROPHOBIC TAILS
ELECTROSTATICS
0%
10%
20%
30%
40%
50%
1 3 5 7# LAYERS
PVAm
PVAm-C8
GROWTH REDUCTION
PVAm, PVAm-C8
-40%
Fibres
CHARGE UP
pH OPTIMIZATION
FIBRE OXIDATION
POLYMER CONTENT (mg/m2)
0 20 40
oxidized fibres
fibres
modelsurface
1 BACTERIA REMOVAL
> 99.9 %
Some remains
2 BACTERIAL GROWTH
# LAYERS ON FIBRES
0,00
0,02
0,04
0,06
0,08
0,10
1 LAYER 3 LAYERS 5 LAYERS Ref
Absorb
ance u
nits
EFFECT OF FIBRE-OXIDATION
0,00
0,04
0,08
0,12
0,16
FIBRES OXIDIZED Ref
Absorb
ance u
nits 24 h
48 h
3 ELECTRON MICROSCOPY
0,0
0,5
1,0
1,5
2,0
FIBRES OXIDIZED Ref
µm
BACTERIAL LENGTH
Ref OXIDIZED
CONTACT-ACTIVE
ANTIBACTERIAL
FIBRES
PULP PROCESSES
ex. CTMP
ACKNOWLEDGEMENTS
VINNOVA, SCA AND BASF
SUPERVISORS MONICA & LARS
COLLEUGES
FAMILY
JOSEFIN ILLERGÅRD [email protected]