disorders of the spinal cord

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    Alvin B. Vibar, M.D.

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    Vertebral columnVertebrae

    cervical 7

    thoracic 12

    lumbar 5

    sacral 5coccygeal 1

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    VertebraAnterior segment

    Posterior segment

    Intervertebral disc

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    SPINAL CORD Lies within the vertebral canal and protected by

    three surrounding fibrous membranes MENINGES

    Held in position by the DENTICULATELIGAMENTS on each side and FILUM TERMINALE

    inferiorly SEGMENTED and paired POSTERIOR / SENSORY

    and ANTERIOR / MOTOR ROOTS correspondingto each segment of the cord leave the vertebralcanal through the INTERVERTEBRAL FORAMINA

    SHORTER than the vertebral column andterminates in the adult at the level oflower borderof first Lumbar vertebra

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    Spinal cordGray and white matter

    Central canal

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    Columns in the White Matter

    Posterior funiculus Lateral funiculus Anterior funiculus

    Each column is subdivided into tracts.These tracts are:Ascending tractDescending tractIntersegmental tracts

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    Parts of the Gray Matter Posterior horn

    Lateral horn

    Anterior horn

    The cell bodies in the gray substanceare grouped into clusters of nuclei oflaminae.

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    Laminae of Rexed - groupings Laminae I VI located in the

    posterior horn

    Lamina VII

    located at thelateral horn

    Laminae VIII and IX located at theanterior horn

    Lamina X

    gray substancesurrounding thecentral canal

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    Spinal cord with laminae of Rexed

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    Ascending Tracts

    Dorsal / PosteriorColumnPosition sense2 pt discrimination

    Fine, discriminativeVibration senseStereognosis

    Spinothalamic tract

    ASTT touch / PLSTT pain & temp

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    Dermatomes Area of the skin supplied by the

    somatosensory fibers from a singlespinal nerve ; useful in localizingthe levels of lesions

    C2 back of head C5

    tip of shoulder

    C6 thumb C7 middle finger C8 small finger T4 T5 nipple T10 umbilicus

    L1

    inguinal L4 L5 big toe S1 small toe S5 perineum

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    Descending Tracts

    Lateral corticospinal

    Rubrospinal

    Lateral reticulospinal

    Medial reticulospinal

    Vestibulospinal

    Tectospinal

    Anterior corticospinal

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    Spinal CordWhite Matter ofSC

    divisible into:

    Anterior Funiculus

    AnteriorCorticospinalVestibulospinalTectospinal

    Reticulospinal

    Lateral Funiculus

    Lateral Corticospinal

    Rubrospinal

    Posterior Funiculus

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    PYRAMIDAL SYSTEM Providesvoluntary control of skeletal muscles

    Owes its name to the pyramidal cells of the primary

    motor cortex Consists of:

    Corticobulbar

    Lateral Corticospinal

    Anterior Corticospinal

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    CORTICOSPINAL TRACTS LCST

    at the lowermedulla,

    axons decussate the midlineto enter on the oppositesideof the SC

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    Signs of Motor Neuron Lesions

    UMNL LMNL

    Paralysis Spastic Flaccid

    Atrophy (-) (+)Fasciculations (-) (+)

    Clonus (+) (-)

    PathologicReflexes

    (+) (-)

    Muscle tone Increased Decreased

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    Lesion of Corticospinal TractAbove the level of decussation, manifest

    contralaterally

    Ex. Stroke involving right motor area of cerebrum left sided paralysis

    Below the level of decussation, manifest

    ipsilaterally Ex. Spinal cord lesion on right side right sided

    paralysis

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    Spinal shock Flaccid, areflexic paralysis

    Complete loss of sensation

    Loss of autonomic function

    Loss of reflex activity - paralysis of the bladderand rectum

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    Destructive Spinal Cord

    SyndromesComplete cord transection

    Anterior cord

    Central cord

    Brown Sequards - Hemisection

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    Spinal cord lesions:

    Syringomyelia

    progressive cavitationaround the central canal; loss of pain &temperature sensations in hands &forearm ( common in cervical)

    Poliomyelitis

    attacks the anterior horncells leading to LMNL

    Tabes Dorsalis caused byneurosyphilis;

    dorsal root involvement with secondarydegeneration of dorsal columns ( loss ofvibration and position sense)

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    Amyotrophic lateral sclerosispuremotor disease involving the degeneration

    of anterior horn cells (LMNL) andcorticospinal tract (UMNL); NO sensoryloss

    Subacute combined degeneration

    caused by vitamin B12 deficiency;degeneration of posterior and lateralcolumns ( loss of position sense and

    vibration in legs associated with UMNL)

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    CASE:

    A 25 y/o male fell to the ground hittinghis lower back against the gutter when hismotorbike skidded on the wet road.

    When he tried to get up, he was unableto move his right leg. He was brought tothe hospital and upon examination, hecould NOT FEEL PAIN on the left side

    up to the level of the umbilicus. Hecould NOT FEEL theVIBRATION of thetuning fork on his right foot.

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    Brown-Sequards syndrome Spinal Cord Hemisection

    Features:

    Contralateral loss of pain & temperature

    Ipsilateral loss of proprioception

    Ipsilateral manifestations of upper and

    lower motor neuron lesions

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    Diagnosis:Syringomyelia progressive cavitation

    around the central canal; loss of pain

    & temperature sensations in hands &forearm ( common in cervical)

    Dissociated sensory loss

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    An 11 y/o girl complained ofpain in the neckand the left shoulder and had a fever of 102 to103 degrees F. A few days later the left arm,forearm and hand were paralyzed; the musclesflaccid. Reflexes in the left upper limb were

    absent. Motor control of the other parts of thebody were intact. After 4 weeks, the forearmand the hand could be slightly extended byvoluntary effort, but no other voluntarymovement of these parts could be executed.The paralyzed muscles remained flaccid andshowed marked atrophy.

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    Diagnosis:

    Poliomyelitis attacks the anterior

    horn cells leading to LMNL ;degenerative lesions

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    45 / M barangay captain from Cagayan

    Hit by an oncoming bus while driving a motorcycle inthe dark No loss of conciousness but was unable to move all

    extremities (+) labored breathing On PE, motor strength : 0/5 all extremities 100% sensory deficit from neck downAreflexic all extremities, flaccid, (-) clonus / Babinski Lax sphincter tone on rectal exam

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    Diagnosis :

    Acute spinal cord injury, complete, C2sensory level, secondary to vehicularaccident

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    33 / M farmer from IloiloWas carrying sacks of grain on his back Sudden sharp, stabbing pain from the lower

    back radiating to the right leg

    On PE, motor strength : 5/5 UE, 4/5 LE , normalmuscle toneDTRs : ++ UE, +++ LE, (-) clonus / BabinskiNo sensory deficitsNormal rectal exam

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    Diagnosis : Herniated lumbardisc, L2-L3 level with nerve root compression

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    THANK YOU and HAPPY NEW YEAR.

    in due time we

    shall reap.

    if we dont lose

    heart.