TB drugs Degraded polymer

1. Drug delivery system implanted into patient

2. Polymer Matrix degradesand drug is released

3. Drug depot released and polymer degraded

TB drugs and Polymer Matrix

The World Health Organization (WHO) declared tuberculosis as a global emergency. One third of the global population is infected, increasing at a rate of one per second on a global scale. The disease is curable, but treatment non-adherence is the major problem.

A SUSTAINABLE CURE FOR TUBERCULOSIS

Microscopy images of drug + polymer microparticles

A Stanford Biodesign project, our goal was to design an implantable device to sustainably deliver drugs over 6 months.

Proposed System

ROLE Drug & Prototype Engineer

Featured on Mercury News Patent Drawings

Prototypes

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Each year in the US, 13 million people are at risk of developingmultiple organ dysfunction syndrome, a result of shock condition. This costs $15 billion a year to treat. It is the largest cause of death in intensive care units and there is no effective way of knowing its onset.

Our goal was to use patented technology to improve the accuracy and precision of shock detection.

A DEVICE TO DETECT SHOCK CONDITIONProbe Design

Based on patented EZ-IO bone drilling technology

ROLE CAD Modeler

Software & Hardware Design

Experimental Set Up

DESIGN PROCESS

HOW IT WORKS

• Fiber optics probe detects biological molecules• Signal gets amplified• Information displayed in user interface

Conclusions

• High accuracy detection of shock condition• High precision provided by immobilized probe • Minimally invasive and real time monitoring

NANOTUBE DESIGNED DNA BIOCHIPS

DNA sequencing speed has accelerated and its cost lowered dramatically in recent years.DNA code translates to proteins, which form traits. The study of proteins (proteonomics), is essential to identify function and expression.

Our goal was to use nanotubes to createa nanogap in biochip fabrication to serveas a shadow mask in photolitography.

ROLE LabView Interface &Hardware Designer

Software Design with Labview

Hardware Design & Data Adquisition