Digital Health SummitInspiring Innovation#BSWHDigital

Nick van Terheyden, MD @drnic1Chief Medical Officer, Dell HCLS

Nick van Terheyden, MD CMO, Dell Health and Life SciencesTwitter http://twitter.com/drnic1LinkedIn http://www.linkedin.com/in/nickvtBlog http://drnick.vanterheyden.com/FaceBook http://www.facebook.com/drnic1E-Mail DrNick@dell.com, drnic1@gmail.comAboutMe http://about.me/obiwanGoogle Voice (301) 355-0877

Where you can find me

Medical Errors 3rd Leading Cause of Death

Consumer Statistics

387 Million globally live with diabetes10 million live with Parkinson's14 Million new cancer cases added each year17 Million people will die annually from heart disease

Ageing is the Seminal Issue of Our Time

By 2050• 40% of people will

be over 60• More people over

60 than under 14

In the United States• 10,000 Baby Boomers

turn 65 every day• All Baby Boomers will

be 65+• 8 Million will be over

80

2009 Continua Health Alliance Brigitte Piniewski, MD

0 25 65AgeIll

ness

Pre-

Illne

ss

Wel

lnes

s

Unpredictable HealthPredictable (Rules-based) Health Deat

h

60-80% Lifestyle

Modifiable Health

8

Genomics, Sequencing and Data• Took $3 Billion and 10 years to sequence

one genome• Sequence in days even hours and for

<$1,000• Explosion of data just to sequence the

genome– Plans to sequence 14M new cancer

patients every year which would generate 5.6 Exabytes of information.

• But there’s even more data in -omics

Global bioinformatics market to reach $13B by

202021% CAGR1

>5.6 Exabytesto sequence 14M new cancer patients worldwide per year2

Sources:1. Allied Market Research, Global Bioinformatics Market, 2013-20202. http://www.cancerresearchuk.org/cancer-info/cancerstats/world/

incidence/3. http://www.technologyreview.com/news/531091/emtech-illumina-says-

228000-human-genomes-will-be-sequenced-this-year/

228,000 whole human genomes sequenced in 2014

1.6M by 20173

• Kilo• Mega• Giga• Tera• Peta• Exa• Zetta• The Data Deluge Makes the

Scientific Method Obsolete

The Data Deluge

10

Fact

s pe

r Dec

isio

n1000

10

100

5

Clinical decision-making is becoming more complicated.

2000 20101990 2020

Structural Genetics: e.g. SNPs, haplotypes

Functional Genetics: Gene expression

profiles

Proteomics and othereffector molecules

Decisions by Clinical Phenotype

William W. Stead, M.D., 2007 AMIA Panel Presentation, “Why We Need Internal Development”, November 11, 2007

How can we expect health care professionals

to review 6 billion pieces of data in a 15 minute encounter?

Hi Tech Medicine

Digital Health SummitInspiring Innovation#BSWHDigital

Nick van Terheyden, MD @drnic1Chief Medical Officer, Dell HCLS

Nick van Terheyden, MD CMO, Dell Health and Life SciencesAboutMe http://about.me/obiwanTwitter http://twitter.com/drnic1LinkedIn http://www.linkedin.com/in/nickvtBlog http://drnick.vanterheyden.com/FaceBook http://profile.to/drnickE-Mail DrNick@dell.com, drnic1@gmail.comGoogle Voice (301) 355-0877

Questions