Diabetic Drugs on Market or In Pipeline at July 6, 2011

Company drug or product indication/substance Phas

e I

Phas

e II

Phas

e III

unde

r rev

iew

on m

arke

t

exte

nsio

n

offs

hore

app

rova

l

t1 and t2 diabetes x x xt1 and t2 diabetes x x xt2 diabetes x x

NN1953 t1 and t2 diabetes xNN9068 t2 diabetes xNN9924 t2 diabetes x

insulin xinsulin xinsulin x

insulin pens diabetes xt2 diabetes xdiabetes xt2 diabetes x

Merck

t2 diabetes xt2 diabetes x

MK3102 xMK0431C diabetes x

diabetes x

diabetes x

diabetes x

diabetes xdiabetes x

AZD1656 diabetes x xAZD8329 diabetes/obesity x xAZD7687 diabetes/obesity x xAZD5658 diabetes/obesity x x

diabetes x

Pfizerx

xx

t2 diabetes xt1 diabetes x xt2 diabetes x

1614235 t2 diabetes x2245840 t2 diabetes x

Eli Lilly

xdiabetes xdiabetes xt2 diabetes xt2 diabetes x

BI10773 diabetes xt2 diabetes x

xdiabetes x

xONGLYZA diabetes xKOMBIGLYZE diabetes x

diabetes x

Abbott xt2 diabetes xt2 diabetes xt2 diabetes x

Novo Nordisk

DegludecDegludecPlusSemaglutide

NovoLog Mix 70/30NovoLogLevamir

PrandinGlucagen hypo kitVictozaJanuviaJanumet

diabetes mellitus

MK0431A (sitagliptin/Extended-release metformin)MK0431D sitagliptin/simvastatin

Astra Zeneca

Kombiglyze™ XR/ Onglyza™/metformin IR FDC#Dapagliflozin/metformin FDC#Dapagliflozin

saxagliptinLyrica diabetic neuropathyLyrica neuropathic painMacugen diabetic macular edema

GlaxoSmithKline

albiglutideotelixizumabalbiglutide

Cymbaltadiabetic peripheral neuropathic pain

HumalogHumulinByetta (w/Amylin)Actos

GLP-1 FcArxxant diabetic retinopathyLinagliptin

Bristol Myers Squibb

Avapro diabetic nephropathy

Dapagliflozin

Bardoxolone methyl chronic kidney disease and t2 diabetes

Amylin Pharmaceuticals

Byetta (w/Eli Lilly)SymlinBydureon