devops culture in life science - usenix · pdf filedevops culture in life science ... intro...

December4–9,2016|Boston,MAwww.usenix.org/lisa16#lisa16

Peter Lega & Jason Victor, Merck

DevOps Culture in Life ScienceImplementing DevOps in a Regulated Traditionally Waterfall Environment

Introductions and About Us

Who we are

Merck & Co., IncHealthcareCompany

125Yearoldhealthcarecompany,intheFortune100,operaKngin140+countries,partofahighly-

regulatedindustry

Applied TechnologyInnovaKonGroup

BringingnewtechnologiestospeedupIT,creaKngnewproductsandmarkets,enablingplaTorm-basedtechnicalecosystems.

Peter LegaDirector,Architecture

AppliedTechnology,formerWeb/ContentManagementleadat

Merck.12yearsinHealthScience.AncientUnixKernelHacker,SiliconValley1.0(c|net),Middleware

geekonWallSt,Europeancommission.AutomaKondweeb.

Jason VictorAssoc.Director,DevOps

ArchitectatMerck,DevOpsLead,15yrsinHealthScience,17yrsinIT,6sigmagreenbelt,ITILPracKKoner,SoawareDeveloper,SupportLead,MastersfromDrexelUniversity,

MoravianCollegeMentor

H3

What we’ll cover todayIntro

There is hopeIt is possible to implement DevOps at a regulated company.

There is opportunityDevOps presents an unprecedented opportunity to accelerate the science and practice of healthcare.

There are still challengesHighly-regulated companies present unique challenges when introducing a technology culture like DevOps.

Our AppoachOur multi-year journey to augment our traditional, waterfall methodology with DevOps/Agile culture and methodology

Tool ChainYou still need technology to support DevOps. We’ll show you what we’re working on.

Cultural ShiftsHow we went from "that will never work" to "that's the new way to work."

Highly Regulated IndustriesDefinition: “a type of business that is controlled by government rules” [2]

Regulations keep consumers/patients/populations safe.

[2] Cambridge English Dictionary

Why Now?

Exploding Sources of Data & Methods

• Longitudinal / IoT • Genomic • Historical • Personalized Medicine • Data-driven invention • Open Data

Talent & Culture• Agile career mindset • Cross-functional Organizations • CrowdSourcing • DEVOPS

The Growing Arsenal of Technology

• Big Data tooling and infrastructure

• Mainstream Platform-driven ecosystems & economies

• Collaborative-based tooling • Quantum • Open Source

It’s the Perfect Storm

“[Y]ounger baby boomers held an average of 11.7 jobs from ages 18 to 48.” [1]

[1] Bureau of Labor Statistics

Impact

Reducing cycle time

Discovering things faster

Health - Improving lives

Year

s

0

3.5

7

10.5

14

DiscoveryPre-clinicalClinicalPhase IVLaunch

Cycle Time [3]

[3] J. A. DiMasi “Metrics on Technical Risks, Clinical Development Times, and Approval Times for Cancer Drugs”

Our 4 Key StrategiesHow?

Community DevOps Platform Improve Over-communicateFosteracommunity-Bobomup

w/KeyDecision-MakersCo-CreateanITstandardDevOps

plaTormIterate,improve,&PublishKPIs Over-communicate

Over-communicateOver-communicate

Foster a CommunityKey executive sponsors in word, wallet and deed.

Delivery-proven SW experts from both traditional and emerging sides.

(regulatory waterfall and agile/DevOps/tech)

The authoritative approvers (quality, compliance)

An effective training and communications group

Key senior SMEs/leaders willing to facilitate cross-organizationally

A set of first-follower business partners.

Software Development Extremes

VS

Traditional Regulated MindsetRisk Averse

Deliver complete solution Specialization and hand-offs

Get it right / lock it down Focused on Quality of Output

Innovation Mindset (Agile)Fail Fast

Minimum Viable Product (MVP) Cross-disciplinary teams Continuous Improvement

Focused on Quality of Output

Agile

Bridging Understanding With “Why”

Why

Traditional Regulated MindsetRisk Averse

Deliver complete solution Specialization and hand-offs

Get it right / lock it down Focused on Quality of Output

Innovation Mindset (Agile)Fail Fast

Minimum Viable Product (MVP) Cross-disciplinary teams Continuous Improvement

Focused on Quality of Output

Decrease FailureDeliver Right ProductIncrease Efficiency

Increase Quality

Agile

From Conflict to SynergyTraditional DevOps

EstablishedSupportandOperaKonsatScale

GlobalCoverage

GlobalCommunicaKonsServices

MatureRegulatoryServices

DeepRegulatoryKnowledge

ViralCollaboraKonEcosystems

IncreasedTransparency

AcceleratedSoawareDelivery

CultureofInnovaKon&InvenKon

IndustryEdgeSensing

From Conflict to Synergy

EstablishedSupportandOperaKonsatScale

GlobalCoverage

GlobalCommunicaKonsServices

MatureRegulatoryServices

DeepRegulatoryKnowledge

ViralCollaboraKonEcosystems

IncreasedTransparency

AcceleratedSoawareDelivery

CultureofInnovaKon&InvenKon

IndustryEdgeSensing

Traditional DevOps AND

Our 4 Key Strategies





Our DevOps Toolchain

Ideas

Collab.Wiki(Confluence)

Tracking(JIRA)

SCM (Bitbucket)

ContinuousIntegration(CI)Orchestration(Jenkins)

ContainerMgmt

Rel.Mgmt

TestMgmtAutoTesting

(RobotFramework)

Search Guardrails

OfficeAPITest Mgmt CMDB

DevOps Program

DefinitiveMediaLibrary

Monitoringtools

TestDataMgmt

InfoSecScans

DeploymentTarget(IaaSandDBaaS)(ContainerorServer)(On-PremorCloud)

IT Automation

Service Management

Service Mgmt

Release Mgmt

IT Automation

CDOrchestration

Iterate, Improve & Gather InsightsProcess that grows over time

Git RepoCollaboration

SuiteAutomate

Partly Qualified Fully Qualified

Start with the basic code check in

Wiki, Issue Tracking

CI / CD Suite

Regulated processes can use pieces of the DevOps Stack

Regulated processes can fully utilize the DevOps Stack

Acceleration of Dev Tools Usage

0

150

300

450

600

Q1 Q2 Q3 Q4 Q1 Q2 Q3

JIRA Bitbucket Confluence

Active Projects

2015 2016

Confluence 3,300

Bitbucket 500

JIRA 1,300

Active User Count

Acceleration of APIs

0

0.2

0.4

0.6

0.8

Jan Feb Mar Apr May Jun Jul Aug Sep

CENTSAPI Costs per user

0

200

400

600

800

J F M A M J J A S O N D J F M A M J J A S

Requests/Month (thousands)GBs/Month

API Usage

2015 2016 2016

Rinse & RepeatIterate, Improve & Gather Insights

Inform the portfolio

Cross project insight & improvement

Sales App

Working MVP in 2 months

Clinical Trials App

6 months instead of 18

Over Communicate

Telling stories

Sharing success

Showing data

Plain English, please

Our 4 Key StrategiesIn the Spirit of Over Communicating…





Impact

Reducing cycle time



Cycle Time

Year

s

0

3.5

7

10.5

14

DiscoveryPre-clinicalClinicalPhase IVLaunch

Impact

Reducing cycle time



Remember - It’s Personal

devops culture in life science - usenix · pdf filedevops culture in life science ... intro...

Documents