developing a search strategy for your systematic review

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Developing your SR search strategy SARAH YOUNG HEALTH SCIENCE AND POLICY LIBRARIAN

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This presentation was made to researchers in public health and nutrition at the Summer Institute for Systematic Reviews in Nutrition for Global Policy Making, a collaboration of WHO, Cochrane Collaboration and Cornell University's Division of Nutritional Sciences.

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Page 1: Developing a search strategy for your systematic review

Developing your SR search strategySARAH YOUNG

HEALTH SCIENCE AND POLICY LIBRARIAN

Page 2: Developing a search strategy for your systematic review

Today’s presentation

Access to library resourcesDeveloping your search strategyReporting of ongoing unpublished trialsUsing library services

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A guide to library resources

http://guides.library.cornell.edu/WHO

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Access to resources: The catalog

https://www.library.cornell.edu/

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Access to full text

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Access to full text: Don’t give up!

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Developing your search strategy

Example: MalnutritionUse both indexing terms and free-text

“Malnutrition"[MeSH] OR “malnutrition” OR “undernutrition" OR “under-nutrition” OR “nutritional deficiency” OR “undernourishment”

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Why use free-text AND indexing terms?

Indexing quality varies by databaseSome articles have not yet been indexedNo abstract includedNon-English material

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Standardized Index Terms

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Standardized Index Terms

HIV"human immuno-deficiency virus" n=199

"HIV"[Mesh] n=80480

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Combine standardized terms with natural languageHIV"human immuno-deficiency virus" n=199

"HIV"[Mesh] n=80480

"HIV"[Mesh] OR "human immuno-deficiency virus" n=80640

We added 160 articles by including the free-text term in the MeSH term search

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Search strategy with harvested terms HIV Infections[MeSH] OR HIV[MeSH] OR hiv[tw] OR hiv-1[tw] OR hiv-2[tw] OR human immunodeficiency virus[tw] OR human immunedeficiency virus[tw] OR human immuno-deficiency virus[tw] OR human immune-deficiency virus[tw]

n= 315017

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Term harvesting

Synonyms in standard index entries Titles and abstracts of key articles Dictionaries and Thesauri

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Example: preterm infant

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Putting together a search strategy

High sensitivity (low precision) Minimize bias Reproducible (documentation)

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Putting together a search strategy

Example:

Micronutrient supplementation in pregnant women with HIV infection The Cochrane Collaboration Siegfried N, Irlam JH, Visser ME, and Rollins NN 2012

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Putting together a search strategy

Objective:

To assess whether micronutrient supplements are effective and safe in reducing mortality and morbidity in pregnant women with HIV infection.

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HIV

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Type of study: RCT

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Micronutrients

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Micronutrients (cont.)

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Micronutrients (combined)

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Final (combined)

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Type of study: RCT

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Search tips: Use the syntax appropriate to the database

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Search tips: Use the syntax appropriate to the database

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Identify text terms

Term harvest for synonyms

Control for spelling variation and use

truncation

Identify indexing terms

Decide to explode or focus indexing terms

Combine all search terms

logically

Customize syntax for other

databases

Perform test searches

Perform test searches

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Choosing databases

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Choosing databasesSearched for reports of maternal mortality and morbidity across various study designs

MEDLINE, Popline, EMBASE, CINAHL, CAB Abstracts, Econlit, Sociofile, LILACS, BIOSIS and PAIS International

2580 citations included

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Choosing databases

MEDLINE EMBASE BIOSIS POPLINE0

20

40

60

80

100

62

44

1712

Percent of Total Citations Identified

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A guide to library resources

http://guides.library.cornell.edu/WHO

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Outside of the published literature

Publication bias

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Other sources: Unpublished clinical trials WHO International Clinical Trials Registry Platform (ICTRP) http://www.who.int/ictrp/en/

metaRegister of Controlled Trials (mRCT) http://www.controlled-trials.com/mrct/

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Other sources: Grey Literature

“…literature that is not formally published in sources such as books or journal articles.”

Cochrane Handbook for Systematic Reviews of Interventions

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Other sources: Grey Literature

"That which is produced on all levels of government, academics, business and industry in print and electronic formats, but which is not controlled by commercial publishers.“

The Fourth International Conference on Grey Literature, Washington, DC

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A guide to library resources

http://guides.library.cornell.edu/WHO

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Finding Mann Library

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Room to work

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Available library services

Access to full text Search strategy development

Using the databases Citation management

Questions about Research4Life

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Help with your research

[email protected] Office hours:

2-4 pm (except tomorrow) Services and Collections offices, 1st floor of Mann

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References Betran, A.P. et al. (2005). “Effectiveness of different databases in identifying studies for systematic reviews: experience from the WHO systematic review of maternal morbidity and mortality”. BMC Medical Research Methodology, 5:6.

Fowler, S. (2013). “Library Resources for Systematic Reviews”. Presentation available from http://www.slideshare.net/referencegirl/sys-revs-colditz.

Higgins, J.P.T. and Green, S. (eds.) (2011). Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0, available from http://handbook.cochrane.org/.

Siegfried, N. et al. (2012). “Micronutrient supplementation in pregnant women with HIV infection (Review)”. The Cochrane Library, Issue 3.