develop cutting-edge machine learning and ai …ml-aim research 1 develop cutting-edge machine...

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ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized healthcare 1) support clinical decisions for the patient at hand 2) understand the basis of health and disease 3) inform and improve clinical pathways, better utilize resources & reduce costs 4) transform public health and policy 1 &

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Page 1: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized

ML-AIM research

1

Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized healthcare1) support clinical decisions for the patient at hand 2) understand the basis of health and disease 3) inform and improve clinical pathways, better utilize resources & reduce costs4) transform public health and policy

1

&

Page 2: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized

Cancer - a useful exemplar

• Common, costly and important group of disorders

• Varied aetiologies, presentations and long-term outcomes

• Complex management affecting multiple clinical systems

• Care delivered through multiple organisations

• Leads in personalised medicine therapeutics & genotype-phenotype correlation

Goal: deliver decision support for the patient at hand

Page 3: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 4: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 5: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized

Select a patient

Page 6: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 7: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized

Upload a pathology report

Page 8: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized

AutoPrognosis[ICML 2018][SciRep 2018][Plos 2019]

Page 9: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized

INVASE [ICLR 2019]

Page 10: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized

ER Positive

ER Negative

Page 11: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
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PASS

Page 13: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 14: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 15: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 16: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 17: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
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Page 19: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized

ASAC[ML4HC 2019]

Page 20: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 21: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 22: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized
Page 23: Develop cutting-edge machine learning and AI …ML-AIM research 1 Develop cutting-edge machine learning and AI theory, methods, algorithms and systems to deliver effective personalized

NSGP [NIPS 2017]GANITE [ICLR 2018]

CMGP [ICML 2018]CounterfactualRecurrent Nets

[NIPS 2018]

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Deep Predictive Clustering