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Page 1: Detels Intro PH150 - ph.ucla.edu

CLASS WEBSITE

Not on CCLI:

http://www.ph.ucla.edu/epi/faculty/detels/PH150/schedule_2013.htm

Page 2: Detels Intro PH150 - ph.ucla.edu

The fundamental maxim of public health is that the health

of the individual is best ensured by maintaining and improving the health of the

community.

David Satcher, 1995

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PUBLIC HEALTHPUBLIC HEALTH

The science and art of preventing disease, prolonging life and promoting health through the organized efforts of society.

Acheson Report, London 1988

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PUBLIC HEALTH IS:PUBLIC HEALTH IS:The process of mobilizing local, state/provincial, national and international resources to assure the conditions in which all people can be healthy.

Breslow/Detels, 1997

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Public health does not guarantee optimal health, but creates the conditions

under which it can be achieved by society

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THE GOAL OF PUBLIC HEALTHTHE GOAL OF PUBLIC HEALTH

The biologic, physical and mental well-being of all members of the global society, regardless of ethnicity, religion, gender, sexual orientation, country or political views.

Detels, 2003

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Public health is an exciting field Public health is an exciting field that can improve the health and that can improve the health and

quality of life for all.quality of life for all.

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OBJECTIVES OF COURSE (1)An understanding of:

The concept and importance of public health, not only for preventing disease, but also for assuring access and the tools to achieve a healthy community and healthy personal lifestyles

The population approach to health, which is the basis of public health

The scope of public health

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OBJECTIVES OF COURSE (2)The major disciplines of public health, their strategies, and how they contribute to assuring the health of the public

The major intervention strategies used by public health to promote the health of the community

The major health problems currently faced by public health in the United States and globally

Barriers to promoting public health and strategies to overcome these barriers

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GLOBAL HEALTH GLOBAL HEALTH PROBLEMS PROBLEMS (EXAMPLES)(EXAMPLES)

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Drugs Now Deadlier than Autos Drugs Now Deadlier than Autos and Guns and Guns

LA Times Sept 18, 2011LA Times Sept 18, 2011

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EPIDEMIC OF FORMULA-ASSOCIATED INFANT DEATH –

China 2008• Melamine in infant formula causes four

deaths• 40,000 children flood health care facilities• 12,900 hospitalized with severe kidney

damage• Chinese milk products recalled in Japan,

Hong Kong, Singapore and Southeast Asia

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European E. coli Outbreak Traced Back To Lot of Fenugreek Seeds Imported From Egypt

The outbreak of shiga-toxin producing E. coli (STEC) in May and June 2011in Europe has now totaled 265 cases with Hemolytic Uremic Syndrome (HUS) and 3151 non-HUS cases and there have been 42 deaths, all but one in Germany. A report from the European Food Safety Authority in early July implicated a particular lot of fenugreek seeds imported from Egypt in December 2009 [http://www.efsa.europa.eu/en/supporting/doc/176e.pdf]. Several seed types (alfalfa, fenugreek, lentils, adzuki beans, and radish) were suspected in Germany, however, a separate cluster of cases occurring in France in June 2011 gave investigators an important clue. While three types of sprouting seeds were implicated in France (fenugreek, mustard, and rocket), only fenugreek seeds were common to both outbreaks. They became the focus of the investigation and were traced back to Egypt. Results from the microbiological tests carried out on seeds have been negative, possibly due to the limitations of the tests used or the sampling plan used to select the seeds for testing. The hypothesis is that the fenugreek seeds became contaminated with STEC 0104:H4, the implicated agent, at some point prior to leaving the Egyptian importer. According to the report, this reflects a production or distribution process which allowedcontamination of fecal material of human or animal origin, possibly at the farm level but still not established.

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LA Times,

Sept 2012

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LA Times, Sept 2012

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This year's outbreak of West Nile virus is the worst since the illness was first observed in the United States in 1999, officials from the U.S. Centers for Disease Control and Prevention said Wednesday. The number of confirmed cases rose by 25% last week to 1,993 -- although

only an estimated 2% to 3% of cases are reported

to the government. Those are generally the most serious infections: Most people who contract the virus do not develop severe symptoms, and many never even know they were infected. The most common symptoms are a fever and neck stiffness. Severe cases can lead to encephalitis or

meningitis.

LA Times, Sept 2012

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Lindsey NP, et al. West Nile Virus and Other Arboviral Diseases — United States, 2012. MMWR 62(25):515, June 29, 2013

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Selkoe DJ. Preventing Alzheimer's disease. Science 337:1488-1492, 2012

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EPIDEMIC OF OBESITY/DIABETES

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http://www.dailymail.co.uk/news/article-499925/Obese-8-months-baby-tips-scales-3-stone.html

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National Center for Health Statistics. MMWR 61(7):130, 2012.

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LA Times, August 16 2013

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LA Times, 21 Sept, 2012

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LA Times, 1 Sept 2010

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Valderrama AL, et al. Vital signs: awareness and treatment of uncontrolledhypertension among adults – United States, 2003-2010. MMWR 61(35):705, 2012.

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LA Times, 24 September 2009

San Pedro port pollution

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Historic Life ExpectancyHistoric Life Expectancy

Source: U.S. DHHS, 2006

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World Health Organization, 2010

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WHO: The World Health Report 2008 http://www.who.int/whr/2008/whr08_en.pdf

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Major Reasons for Increased Major Reasons for Increased LongevityLongevity

• Improved sanitation• Provision of clean water• Universal immunization programs• Health education and prevention practices• Improved treatment and prevention of

chronic diseases (for recent advances)

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Stone R. Asia’s looming social challenge: coping with the elder boom. Science 330:1599, 2010

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LA Times, Sept 2012

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Top Ten Causes of Deaths World-Wide

http://www.who.int/mediacentre/factsheets/fs310/en/index.html

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Top Ten Causes of Deaths in Low-Income Countries

http://www.who.int/mediacentre/factsheets/fs310/en/index.html

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Top Ten Causes of Deaths in High-Income Countries

http://www.who.int/mediacentre/factsheets/fs310/en/index.html

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World Health Organization, 2010

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http://www.who.int/healthinfo/global_burden_disease/GBD_report_2004update_part2.pdf

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http://www.who.int/healthinfo/global_burden_disease/GlobalHealthRisks_report_full.pdf

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http://ucatlas.ucsc.edu/cause.php

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Non-communicable disease deaths; http://www.who.int/nmh/publications/ncd_report_full_en.pdf

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http://www.who.int/nmh/publications/ncd_report_full_en.pdf

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http://www.globalhealth.org/infectious_diseases/global_view/

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http://www.who.int/healthinfo/global_burden_disease/GlobalHealthRisks_report_full.pdf

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http://www.globalhealthfacts.org/data/topic/map.aspx?ind=91&gclid=CLCeqKC72aoCFVAaQgodIwM58g

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Disability-Adjusted Life Years (DALYS)

One DALY can be thought of as one lost year of "healthy" life. The sum of these DALYs across the population, or the burden of disease, can be thought of as a measurement of the gap between current health status and an ideal health situation where the entire population lives to an advanced age, free of disease and disability.DALYs for a disease or health condition are calculated as the sum of the Years of Life Lost (YLL) due to premature mortality in the population and the Years Lost due to Disability (YLD) for incident cases of the health condition.Calculation: The YLL basically correspond to the number of deaths multiplied by the standard life expectancy at the age at which death occurs. The basic formula for YLL (without yet including other social preferences discussed below), is the following for a given cause, age and sex:where:N = number of deathsL = standard life expectancy at age of death in years

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Panel A shows the percentage of total DALYs due to noncommunicable diseases in each country. Noncommunicablediseases are defined in the hierarchical list of causes11 in the Global Burden of Disease 2010 study and include the following major cause groups: cancers; cardiovascular and circulatory diseases; chronic res piratory diseases; cirrhosis; digestive diseases; neurologic conditions; mental and behavioral disorders; diabetes; urogenital, blood, and endocrine diseases; musculoskeletal diseases; and other noncommunicable diseases such as congenital anomalies and skin diseases

Figure 1. Percentage of Total Disability-Adjusted Life-Years (DALYs) in 2010 According to Country (pt 1)

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Panel B shows the percentage of total DALYs due to years lived with disability per country

Murray CLJ et al. Measuring the Global Burden of Disease. N Engl J Med 2013;369:448-57

Figure 1. Percentage of Total Disability-Adjusted Life-Years (DALYs) in 2010 According to Country (pt 2)

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World Health Organization 2010

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Years of Potential Life Lost from Unintentional Injuries Among Persons Aged 0-19 Years—United States, 2000-2009. MMWR 61(41):833, 2012.

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World Health Organization 2010

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Shuman EK. Global climate change and infectious diseases. NEJM 362:1062, 2010

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http://www.globalhealth.org/infectious_diseases/global_view/

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Health in the U.S.

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Welcome to Downey*Welcome to Downey*

**but donbut don’’t drink the watert drink the water

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Health Care Crisis in the U.S.

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30 Million Americans Without Health Insurance

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LA Times: Bridging a gap in care. Free dental services at LA Sports Arena, 28 April 2010.

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Anderson GF, et al. Reevaluating “Made in America”— Two Cost-Containment Ideas from Abroad. NEJM 368;24 ne.

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Leading causes of death in the United States Leading causes of death in the United States (1900, 1950, 1990, 1997, 2001)(1900, 1950, 1990, 1997, 2001)

Rates

15161923─Motor vehicle injuries

781051Homicide and legal intervention

1011121111Suicide

5610──HIV Infection 22131426210Pneumonia and influenza

2513121413Diabetes mellitus

4413204─Chronic obstructive lung disease

58262889134Cerebrovascular disease

19612613512581Malignant neoplasms

248131152307167Disease of Heart

20011997199019501900

*Age-adjusted per 100,000

Source: McGinnis and Foege (1993); US DHHS (2003)

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Schroeder, NEJM 357(12):1222, 2007

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Schroeder, NEJM 357(12):1223, 2007

Numbers of U.S. Deaths from Behavior Causes, 2002

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In Essential Concepts of Healthy Living, 5th ed, Jones & Bartlett, 2009, p. 5.

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Paul Conrad. LA Times, 4 Sept 2010.

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Life expectancy at birth and at 65 years of Life expectancy at birth and at 65 years of age in the United States age in the United States

(1900, 1950, 1997, 2001, 2004)(1900, 1950, 1997, 2001, 2004)

0.4

0.4

18.1

18.7

0.7

0.6

77.2

77.8

2001

2004

3.817.78.376.51997

2.013.920.968.21950

─11.9─47.31900

GainAt 65 years GainAt birth

Source: US DHHS

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U.S. life expectancy 2004 U.S. life expectancy 2004 –– AfricanAfrican--American vs. CaucasianAmerican vs. Caucasian

Male At Birth At 65 YearsCaucasian 75.7 years 17.2 yearsAfrican-American 69.5 years 15.2 yearsDifference 6.2 years 2.0 years

Female At Birth At 65 YearsCaucasian 80.8 years 20.0 yearsAfrican-American 76.3 years 18.6 yearsDifference 4.5 years 1.4 years

Source: U.S. DHHS, 2006

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LA Times, September 8 2013

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MAJOR PREVENTABLE RISK MAJOR PREVENTABLE RISK FACTORSFACTORS

• Substance abuse– Tobacco– Alcohol– Drugs

• Unhealthy diet• Physical inactivity• Environmental/occupational hazards

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SMOKING FACTS SMOKING FACTS -- 20102010• #1 cause of preventable deaths

(446,000/yr)• >50% of children exposed to second-

hand smoke• 24% of men and 18% of women smoke• 31% of smokers earn wages below

poverty line

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THE SCOPE OF PUBLIC HEALTH (1)THE SCOPE OF PUBLIC HEALTH (1)• Infectious diseases• Chronic diseases

– Heart disease, metabolic disorders, cancer, etc.

– Mental health• Nutrition disorders• Health of the vulnerable

– e.g. poor, children, women, elderly, etc.– Substance abusers: drugs, alcohol,

tobacco

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THE SCOPE OF PUBLICTHE SCOPE OF PUBLICHEALTH (2)HEALTH (2)

• Accidents/violence/injuries• Health equity• Occupational health• Environmental health• Access to health care• Quality of health care• War

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STRATEGIES OF PUBLIC STRATEGIES OF PUBLIC HEALTH (1)HEALTH (1)

• Assess the current health situation– Surveys– Surveillance– Morbidity and mortality reporting

• Identify the problem

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STRATEGIES OF PUBLIC STRATEGIES OF PUBLIC HEALTH (2)HEALTH (2)

• Research correlates of occurrence• Develop and evaluate interventions• Disseminate results• Influence policy to incorporate results

(science-based policy)

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INTERVENTION STRATEGIESINTERVENTION STRATEGIES

• Immunization programs• Health education• Behavioral modification strategies• Community intervention/mobilization• Structural interventions (laws,

regulations)