dengue project

8/10/2019 Dengue Project

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INVOLVEMENT OF THE L

IN DENGUE INFECTIONS


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BACKGROUND

DENGUE FEVER / DHF is a reemerging disease in !e r"#T!e disease is $a'sed () * $%"se%) re%aed deng'e +ir'ses ransmied () aedes m"s,'i"es #rin$i#a%%) aedes aeg)#

Deng'e in-e$i"n $"nin'es " (e a ma"r $!a%%enge " #'es#e$ia%%) in s"'! eas asia .

An a+erage "- 0 #aiens are admied in "'r !"s#ia% 12im

deng'e -e+er #er da). As #er !e %aes re$"rds *4* #aienadmied &i! deng'e -e+er in !e m"n! "- ma) in Tri+and%as 5 m"n!s 67* $"n8rmed deng'e -e+er $ases &ere re2era%a .O' "- &!i$! 6649 &ere -r"m Tri+andr'm.

T!is daa $%ear%) de#i$s !e in$reasing rae "- deng'e -e+Tri+andr'm.


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I !as a &ide ge"gra#!i$a% disri('i"n and #resen &i! di+s#e$r'm . DHF and deng'e s!"$2 s)ndr"me re#resen !e"- disease s#e$r'm &!i$! i- n" #r"#er%) managed &"'%d rsigni8$an m"ra%i).

A%!"'g! deng'e +ir's is n" a !e#a"r"#i$ +ir's : %i+er in'deng'e in-e$i"n is n" 'n$"mm"n . T!e degree "- %i+er d)sdeng'e -e+er +aries -r"m mi%d in'r) &i! e%e+ai"n "- amin

a%"ne " se+ere in'r) &i! a'ndi$e and e+en -'%minan !e#T!e %i+er d)s-'n$i"n $"'%d (e a dire$ +ira% e;e$ "r a $"nsd)sreg'%aed !"s imm'ne res#"nse agains !e +ir's . T!e!e#ai$ d)s-'n$i"n !as (een ass"$iaed &i! disease se+e%i+er in'r) !as (een #r"#"sed " (e a g""d #redi$i+e -a$"de+e%"#men "- DHF.


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Red'$ing deng'e m"ra%i) re,'ires an "rgani


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O(e$i+es

T" assess !e degree "- %i+er in+"%+emen in deng'e #aienNS6 "r deng'e IgM #"sii+e .


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METHODOLOG=

S'd) design > H"s#ia% (ased des$ri#i+e s'd).

S"'r$e "- Daa> in#aiens aending KIMS !"s#ia%.

Me!"d "- $"%%e$i"n "- daa > ?'r#"se "- s'd) &i%% (e e@#%#aien #resr'$red #r"-"rm" &i%% (e 'sed " re$"rd !e rin-"rmai"n -r"m indi+id'a% $ase se%e$ed -"r !e s'd). 50 -'%8%% !e -"%%"&ing in$%'si"n $rieria &i%% (e se%e$ed -"r !


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INCLUSION CRITERIA

In-"rmed $"nsen

Deng'e $ases &i! ei!er NS 6 #"sii+e "r deng'e IgM #"s

Age a("+e 64 )rs


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E@$%'si"n $rieria

Age %ess !an 64 )rs

Ass"$iaed in-e$i"ns 2n"&n " $a'se !e#ai$ in+"%+emeneneri$ -e+er : !e#aiis.


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LIVER INUR= GRADING S=STEM

T!e degree "- %i+er damage &i%% (e assessed a$$"rding " !%i+er en


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Ani$i#aed "'$"me

LFT 1es#e$ia%%) AST3 ma) (e 'sed " #redi$ !e se+eri)"'$"me in deng'e in-e$i"n .

I- LFT -"'nd raised in !e ear%) -e(ri%e #!ase : !e#a"#r"ma) (e $"nsidered " #re+en %i+er damage .


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PROFORMANAME:AGESEXADDRESSDATEOF ADMISSION :DATEOF DISCHARGE:DENGUE IGM:DENGUE NS1ANTIGEN:CHIEFCOMPL AINTSFEVER/HEAD ACHE/ RETROORBITAL PAIN /ARTHRALGIA/MYAL GIA/VOMITING/ABDOMI NALPAIN/JA UNDICE/ALTEREDSENSORIUMHAEMORRHAGIC MANIFESTATIONS: ECCYMOSIS / BLEEDINGGUMS / RASH/EPISTATSIS /HEAMETEMESIS/MALENA/ PERVAGINA LBLEEDINGPASTHISTORY DM/ HTN/JAUNDICE

PERSONALH ISTORY :ALCOH OL/SMOKI NG/USE OF HEPATOPROTECTIVE DRUGSGCSPALLOR/ICTR US/CYANOSIS/CLUBBING/ LYMPHADENOPATHY/EDEMAVITALSIGNS

TEMPERATURE :HEARTRATE :RESPIRATORY RATE :BLOODPRESSURE:SYSTEMIC EXAMINATIONPER ABDOMEN:CARDIVASCULAR:RESPIRATORY :CENTRALNERVOUSSYSTEM:INVESTIGATIONSLFTTotal!l!"#!$:D!"%&t !l!"#!$:Total'"ot%!$:

Al#(!$:AST:ALT:ALP:

CBCHB:PCV:PLATELET:PT:APTT:VIRALMARKERS :)IDALTEST:OUTCOME OFTHE PATIENT:


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THANK =OU

dengue project

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