OCT - DEC 2014Fourth Quarter

Enrichingresearch efforts

worldwide

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Esco News • Oct - Dec 2014|2 Table of Contents

Letter from the CEO

Esco India have shifted

Esco Medical welcomes its newest member

Newest NSF accredited BSC field certifiers

Esco GB Ltd – heavily investing in new state-of-the-art premises, warehouse and training location!

03

05050606

Table of Contents

Esco honored at Singapore Prestige Brand Awards

Family success stories with the Esco Miri®

04

Seminars on biosafety, accomplished byEsco China

15

10

News__________________________________________________

Esco fume hoods to keep students safe at St. Brendan's College in Bristol

Biosafety and biosecurity in different sectors,Esco 4P framework and how to achieve them

07

08

Laboratory__________________________________________________

Visit our Spanish website

New products on board

Spotted on TV!

131314

Technology and Innovation__________________________________________________

European sales and distributors training

South America distributors training

Esco GB Ltd hosted the 2014 training at its new premises in Barnsley

15

Trainings and Seminars__________________________________________________

Uncovering research solutions across the globe

Meet Esco at the following events

1921

Events__________________________________________________

Esco Product Guide22

Products__________________________________________________

World Class. Worldwide.23

Global Network__________________________________________________

World class. Worldwide.14

Global Network__________________________________________________SCAN THE QR CODEto learn more about Escowww.escoglobal.com

Esco strengthens biosafety and biosecurity awareness in Bangladesh

18

Miri® TL advancing in vitro fertilization in Spain

Esco IVF incubators, ANVISA approved!

VIP treatment for cultured embryos in ART

10

Medical__________________________________________________

1111

1617

Esco News • Oct - Dec 2014 | 3

Dear Colleagues and Partners: As we look back on 2014, we can be proud of the new heights which Esco Group has scaled.

New sales offices were established in Hong Kong, Thailand, Italy, Russia and Bangladesh. And since the best products in the industry also demand the best support, Esco continues to expand our sales, marketing and service teams with hires in the US, Europe and across Asia.

The current product portfolio was enhanced while the pipeline of new products remains robust. Sample protection software solutions have been launched including the SampleTracker, Voyager, iRMAP, and PROtect. CO2 incubator range has been expanded with two more competitive products and more products will be announced in 2015.

Esco Pharma and Esco Medical divisions have recorded excellent sales growth.

Esco GB relocated to new larger facilities in the UK with integrated warehousing and product development to meet the increasing demand of high quality laboratory equipment in the UK and Ireland.

The European business is being strengthened by a new logistics platform in Germany to reduce delivery lead times.

Operational effectiveness has been enhanced with the implementation of a CRM platform and bringing more subsidiaries on the ERP platform.

Esco Ventures was established and is making investments in life sciences and medical technologies.

I would like to extend my very best wishes to you and your families for the holiday season.

Regards,

XQ Lin Group President & CEO Esco Group of Companies

Letter from the CEO

Letter from the CEO

Lin Xiang Qian, CEO

Esco fume hoods to keep students safe at St. Brendan's College in Bristol

Biosafety and biosecurity in different sectors,Esco 4P framework and how to achieve them

Laboratory__________________________________________________

Events__________________________________________________

Products__________________________________________________

Global Network__________________________________________________

Global Network__________________________________________________

Medical__________________________________________________

Esco News • Oct - Dec 2014|4 News

Last October 22, 2014, the Singapore Prestige Brand Award (SPBA) recognized and honoured Singapore brands which have been developed and managed effectively through various branding initiatives.

At the award ceremony, Esco clinched the title for the overall winner in the Maybank Regional Brands category.

Esco is the only life sciences tools manufacturer from the Asia-ex Japan region with a global brand and sales/marketing/service footprint in over 100 countries. Esco competes with the world’s leading life sciences multinationals from the US, Europe and Japan. Esco has been able to brand its proprietary products and successfully differentiated itself against these players, and became an Asian giant in the industry. Managed from their global headquarters in Singapore, the Esco brand is today well established and recognized by the world’s leading scientists and researchers across the US, Europe, and Asia.

As Esco takes the opportunity to respond to the world’s needs, we aim not just to contribute in the advancement of scientific discoveries but also to make the world a safer, healthier and a better place to live with.

Esco pledges to stand by their promise for the next generations to come.

World Class. Worldwide. is more than just a phrase. It’s part of who they are, where they are from and where they are going. Cheers to Esco!

Esco Honored at the Singapore Prestige Brand Award!

Evaluations were based on the success of Esco’s penetration in foreign markets and the internationalization efforts and the proliferation of the company in various foreign markets throughout the years.

Esco has established a well-designed brand identity system in place which expressively communicated its brand in foreign markets through logo, applications and documentations.

Esco was able to present a clear insight and articulation of its brand which differentiated itself from its competitors. Esco also defined the framework of its roadmap, and set the overall precedence of its brand’s existence and behaviour.

Through the continuous brand development and increasing business performance, Esco has shown that its initiatives in improving over the years has exceeded beyond expectations.

Lim Lay Yew, together with Esco Staff at SPBA Awards Night

XQ Lin, leftmost, receiving the plaque of recognition during SPBA Winners Press Conference

Esco News • Oct - Dec 2014 | 5News

We are proud to announce that due to our remarkable growth over the last 10 years, we have expanded and moved to our new office. The new location allows us to facilitate better customer support.

We take this opportunity to thank our customers for being part of this improvement. Your valuable feedback, guidance, and patience have helped us tremendously to achieve what we are today.

We look forward to receive your kind and encouraging patronage to us.

Assuring you of our continued commitment in providing quality products and services, and our desire to contribute significantly towards success of your plans and activities, we remain.

Our new address and contact numbers are:

111-114, Agarwal B2B Commercial Centre,

Kanchpada, Malad (W),

Mumbai – 400 064.

Tel: +91 22 2844 3636 / 2880 3636 / 2889 1375 / 2889 3535

Fax: +91 22 2889 3636 / 2880 3738

Email: info@escobiotech.in

Esco India have shifted

We are pleased to introduce Morten Kristensen as the newest member of the Esco Medical Medical Team, based in Denmark.

Morten will support Esco in installations, trainings, service and maintenance of IVF equipment, mainly on Miri® TL Time Lapse Embryo Incubator. He previously worked with Fertilitech in a similar position for the past years servicing on Embryoscope. In addition, Morten spent a lot of time annotating embryos, why he for sure is the person worldwide having annotated most time-lapse movies (+12,000 cycles), which he also did while working in his previous job.

In his spare time, Morten is a dedicated hunting- and fishing-man. It’s not something that he shouts out loud, but he actually holds the world record for catching the biggest catfish, which he did during a project in Greenland a couple of years back.

Every addition to our family further strengthens our team and proves that Esco Medical is continuously growing having the most competent IVF products and highly qualified staff.

Welcome to the Esco Family!

Esco Medical welcomes its newest member

Morten Kristensen

Esco News • Oct - Dec 2014|6 News

Newest NSF accredited BSC field certifiers

We are proud to announce that Esco has added another three NSF Accredited Class II Biosafety Cabinet Field Certifiers to its roster. Petrus Paolo Carbonell, Sales Manager; Michael Cruzado, Service Engineer; Neil Wayne Fernandez, Sales Manager, have recently passed the NSF accreditation requirements. This is in addition to four other field certifiers.

The NSF accreditation program evaluates the proficiency of individuals who perform routine field certification of biological safety cabinets. The program includes written exam which covers areas such as testing, biosafety, decontamination and cabinet design, and practical exam to evaluate an applicant’s ability to perform all of the tests identified in the NSF/ANSI Standard 49 Biosafety Cabinetry: Design, Construction, Performance, and Field Certification.

With this recent achievement, Esco again demonstrates its being an Excellent Service Company.

Congratulations to the new certifiers! The Esco family is proud of you.

Esco GB Ltd is now running two state-of-the-art premises in Barnsley and Rotherham. Esco GB has outgrown the premises in Rotherham and is now running the Rotherham site purely to account for products, services, project management demands as part of Esco’s Pharma Division. The new premises in Barnsley cater to the growing needs of Esco GB Lab and Medical Divisions.

Esco GB is now operating their own hub and warehouse in Barnsley to meet the increasing demand of high quality laboratory equipment in UK and Ireland. Being closer than ever to customers and channel partners, the Esco GB team is looking to honour long-time relationships by offering trainings and seminars at the new location in Barnsley, just off the M1. The first training was held 4-9 December, more are demanded and will be announced January 2015.

Knowing the importance of after sales support, Esco decided to invest in our own dedicated service engineers. Together with approved service partners Esco ensures high quality and on time servicing of equipment throughout UK / Ireland.

Esco GB Pharma is set up as a regional HQ /factory for EMEA in Rotherham to provide project engineering and fabrication of bespoke Air-flow/Isolation Containment solutions for the life science industry. This alongside with existing factories in Singapore & USA means that Esco Pharma has 3 factories globally catering to regional needs.

Petrus Paolo Carbonell

Michael Cruzado

Esco GB entrance

Esco GB warehouse

Esco GB Ltd – heavily investing in new state-of-the-art premises, warehouse and training location

In close collaboration with Esco GB Lab / Medical division Esco GB now provides both standard and bespoke airflow and containment solutions across the entire spectrum of hazards, from potent/hazardous powders to biological hazards, chemical hazards, aeroallergens, and nuisance powders to our common clients making Esco GB the largest supplier of clean air / containment airflow solutions within UK / Ireland

Esco News • Oct - Dec 2014 | 7Laboratory

When Severn Sales received an inquiry from St Brendan’s Sixth form College in Bristol to install seven ducted fume hoods into a new chemistry laboratory, they turned to Esco because of the need for a reliable supplier who could deliver a quality product on time and position the units on the base cabinets, ready for Severn Sales installation and commissioning team to install the fans and PVC extract ductwork.

St Brendan’s Sixth Form College was almost entirely rebuilt in 2009 to provide university standard resources in world class accommodation.

The college is located on the outskirts of Bristol, within a historic landscape, with very pleasant grounds, which are used and enjoyed by students throughout the year. As part of the capital investment, the College has ensured that its provision of technology is at the ‘cutting edge’. Equipment and software provided is the same as that used by higher education and industry. This focus on providing specialist facilities, dedicated to meeting the needs of post 16 students, applies to all the College accommodation. This makes St Brendan’s an ideal and enjoyable place to study.

All buildings have been designed to minimize the College’s impact on the environment, utilizing the earth’s natural resources, such as sunlight and rainwater. They are designed to minimize the carbon emissions whilst providing a very comfortable place to work and study.

The fans were installed on the flat roof of the college, towards the rear of the building where the visual impact would be minimal.

Esco delivered the hoods to site and the modern design and smart look of the finished installation were pleasing to both the contractor and the college.

Esco fume hoods, to keep students safe at St. Brendan’s College in Bristol

St. Brendan’s College Esco fume hoods at St. Brendan’s College

“The students and staff are delighted with the new Chemistry laboratory. The works were done on a very tight schedule but were delivered on time and ready for the start of term”. Dr Jo Lewthwaite – Saint Brendan’s Sixth Form College.

“We would certainly use Esco again, they are great people to work with and the fume hoods are well-designed, quality products”. Geoff Biggs – Partner, Severn Sales laboratory equipment, Furniture and projects division.

Esco News • Oct - Dec 2014|8

Biosafety and biosecurity in different sectors, Esco 4P framework and how to achieve themLim Lay Yew

Human, Animal and Plant life and health protection of the Environment are inextricably linked and this is the fundamental rationale for an integrated approach to biosecurity. Biosecurity hazards of various types exist in each sector and have potential to move between sectors. For instance, animal pathogens affect humans and animal feeds can be contaminated by mycotoxins and plant toxins.

Esco’s 4P Framework

PREVENTION OF ENTRY/EXITIn research laboratories, biosafety level has been categorized from BSL 1 to 4 to protect entry and exit of pathogens and disease-causing microorganisms depending on the threats posed by the nature of the organism used for research purpose in the laboratory. The levels are designated in ascending order, by degree of protection provided to personnel, the environment, and the community.

Aircrafts and airports also are being “disinsected” for invertebrates: pests or vectors of animal, plant or human disease. Airports also use scanners for contagious disease carrying human hosts like Ebola and SARS.

PREVENTION OF GENERATIONEmphasis on eradication of diseases in plants , animals and humans to protect future generations from biohazards. In plants, prevention of generation includes crop rotation, destruction of the diseased plants, elimination of alternate host plants, pruning, disinfection, and heat treatments.

In animals, ensuring the existence of an assured capability for immediate response to threat outbreaks whether this is through using national resources or requesting rapid assistance from international resources such as FAO Emergency Prevention System (EMPRES). A combination of prophylactic vaccination and zoo sanitary controls to bring the number of outbreaks down to zero and maintenance of appropriate inter-country sanitary cordons until such time as there is regional concurrence that neighbouring countries no longer pose a risk of re-infection. In Humans, the eradication of disease, extinction of the disease pathogens and elimination of the occurrence of a given disease is of utmost importance. According to UNICEF, seven diseases have been under control due to vaccine. These includes small pox, diphtheria, tetanus, yellow fever, whooping cough, polio, and measles.

PURGINGPurging is necessary if the disease has high rates of morbidity and mortality; the disease is highly communicable and spreads rapidly once introduced into non-immune herds.

A quarantine or medical isolation is used to separate and restrict the movement of persons; it is a state of enforced isolation in connection to disease and illness exposed to a communicable disease. The word comes from Italian (seventeenth-century Venetian) “quaranta”, meaning forty, which is the number of days ships were required to be isolated before passengers and crew could go ashore during the black death plague epidemic. Quarantine can be applied to humans, but also to animals of various kinds, and both as part of border control as well as within a country.

Laboratory

Lim Lay Yew, sharing his expertise on Biosafety and Biosecurity Lim Lay Yew accepting appreciation from the organizers of the event

Esco News • Oct - Dec 2014 | 9Laboratory

PERSONNEL CONTROL AND MANAGEMENTThis involves utilizing human resources and making sure that: • They are equipped with technical knowledge and skills to carry out different biosecurity roles and functions • They are prepared to deal with emergencies in the event of disease outbreak and other forms of risk. • They strictly follow standard operating procedures (SOPs) • They use the appropriate personal protective equipment, correct tools and laboratory equipment.

In achieving the 4P’s, ACCCG is necessary; attitude, communication, competence, commitment and growth.

ATTITUDEA correct mindset and attitude is the first important factor in achieving the 4Ps. The right attitude will create an objective that will benefit all stakeholders in different sectors. These benefits include how to improve regulatory and policy frameworks at different sectors (human health & environment, animal and plant sciences) both at national and international level, maximizing resources to achieve objectives and risk analysis and how to manage them.

COMMUNICATIONCommunication is the second important factor in achieving the 4Ps. Exchange of information should be channeled to all stakeholders including government agencies, non-government agencies, private sectors, national and international organizations/policy makers, scientific and research companies/personnel, and the general public. Each stakeholder must be open to communicate on how do they apply their health and environment safety, animal and plant regulations. Communication also improves data acquisition and shared practices among each sectors.

COMPETENCECompetent personnel/authorities should be responsible in establishing integrated biosecurity controls and to ensure that they are properly implemented and monitored by different sectors. Implementing national biosecurity should have human resources equipped with technical knowledge and skills to carry out different biosecurity roles and functions. Training practices, materials and programs can be shared across sectors which can give rise to technical exchanges between countries.

COMMITMENTCommitment is an another important factor in achieving an integrated approach to biosecurity and should be mainly driven by government agencies, national and international organizations, private sectors/different industries and the scientific and research community.

GROWTHHow to continuously GROW is another major challenge. This is the main reason why we need to establish the correct ATTITUDE first, so COMMUNICATIONS and information exchange are shared, we must also have COMPETENT authorities and human resources with adequate technical capabilities and COMMITMENT from different stakeholders. If all of these are implemented then continuous GROWTH on all sectors at different aspects of the 4Ps will follow.

Lim Lay Yew as Guest of Honor Lim Lay Yew accepting Plaque of Appreciation from the organizers of the event

Esco News • Oct - Dec 2014|10 Medical

Miri® TL advancing in vitro fertilization in SpainThe Human Reproduction Unit of the General Hospital of Valencia has been elected to participate in an international project in which they will test the leading technology of Miri® TL incubator for IVF. This project will take place in four European hospitals, one of which is the Spanish ‘’General Hospital of Valencia’’, the only Spanish one included in the project. As reported by the Government in a statement, the incubator has two “key elements” that makes it different from other embryo culture systems. First, is that the unit works with low oxygen pressures improving the cells’ development, and second is its time lapse system which allows them to take images every five minutes and generate a video of the whole evolution of each embryo as images are digitally stored.

Conventionally, the embryos are being removed from an incubator once a day and check their evolution under a microscope. This is a very critical step since the environmental condition could be changed instantly which may induce risks to the embryo development. Meanwhile, with the Miri® TL Time Lapse Embryo Incubator, images can be captured without causing any disturbance to the embryo. The temperature and pH are not altered while morphology is being displayed. Another advantage is the 6 incubation chamber, each allows individual cultivation of 14 embryos, thus can cultivate a total of 84 embryos in one run.

The birth of a child is a fulfillment of every couple’s dream, especially to those who are trying to conceive over the years.

At exactly 3:27pm, on the 18th day of August 2014, a couple became parents with the birth of a baby girl who was conceived through in vitro fertilization. These proud parents were assisted by Dr. Sascha Edelstein, an OB-GYN withsub-specialty training in Reproductive Medicine, at HART fertility clinic.

The clinic has been using the Esco Miri® Multiroom Benchtop Incubator which has been a temporary home for their viable embryos. The unit provides stable and appropriate culture environment required for optimizing embryo development because it offers reduced time spent in handling process of embryo cultures, and minimized disturbances during monitoring due to its completely separate chambers, a feature that is unique to Miri®.

The undeniable competence of the HART Team led by Dr. Edelstein and the outstanding performance of Miri® during embryo development resulted to another birth. A healthy baby boy was born on the 21st day of October this year.

Family success stories with the Esco Miri®

Several fertility clinics around the world have chosen Miri® IVF Incubator to be their partner because of its unparalleled features and design. And together with Miri® TL Time Lapse Embryo Incubator, and Fertilisafe™ IVF Workstation, we guarantee that we will continue helping every fertility clinic’s mission of achieving high pregnancy rates for a more family success stories.

The Holistic Assisted Reproduction Treatment (HART) Team is dedicated to providing holistic fertility treatment tailored to every individual’s needs. Located at Cape Town, South Africa, the Team is consists of professionals with a deep understanding of the physical, emotional & financial hurdles of in vitro fertilization.

Source: http://www.fertilityspecialist.co.za

The birth of the new Miri baby

Staff of General Hospital de Valencis monitoring embryo in the Miri® TL

Esco News • Oct - Dec 2014 | 11Medical

Esco’s Miri® TL Time Lapse Embryo Incubator and Miri® Multiroom Incubator have been approved by ANVISA for Brazil which gives Esco and its partners an opportunity to sell these medical devices and expand their business in the country. It is believed that with its mature healthcare system, Brazil represents the largest medical equipment market in South America and one of the largest markets in the world. With regards to assisted reproduction, Brazil has been very successful over the years. In fact, according to ANVISA, success in fertilization in 2012 achieved the average of 73%, which is inside the international quality standards which vary from 65-75%. In the 6th SisEmbrio Report (Embryo Production National System Report), there are 91 IVF clinics in the country.

Miri® TL and Miri® Embryo Incubators are two highly competitive products that can support the need of each IVF clinic not only to maintain but to increase the success rates of assisted reproduction in Brazil. These products together with Fertilisafe™ Multizone ART Workstation will be every embryologist’s allies in ensuring safety and integrity of each embryo during the process.

ANVISA’s approval highlights the quality of products that Esco manufactures and demonstrates the great efforts done by the people behind this accomplishment.

Cheers to Esco Medical Team for yet another big leap!

The Agência Nacional de Vigilância Sanitária (ANVISA) also known as the Brazilian Health Surveillance Agency is a governmental regulatory agency that aims to protect and promote public health and to intervene in the risks caused by the production and use of products.

Source: http://portal.anvisa.gov.br

Esco IVF incubators, ANVISA approved!

Miri® TL Time Lapse Incubator Miri® Multi-room Incubator

The company who is leading this project and is testing Miri® TL technology has chosen The General Hospital of Valencia due to the ‘’accredited experience’’ of the embryologist Irene Cuevas, Laboratory Manager in the Human Reproduction Unit. She has undertaken important projects for the development of high technology tools in this matter.

Cuevas stated, “Now, we will be able to know not only the rate of loss of events, we will know the whole process from the time that the embryo was placed inside the incubator until the time of transfer. Furthermore, we can now analyze which of the embryos registers the optimum features according to morphology and morphogenetics. This means a great advancement in embryology”.

Juan Gilabert Estelles, Manager of the Maternal and Child Clinical Area and Director of the Medical & Surgery Simulation Area in the General Hospital, stated that this technology will allow the Hospital to become a key reference for the study of the evolution of embryos as well as the best place to work for specialists in this field.

VIP treatment for cultured embryos in ARTIVF Incubators serve as temporary homes for embryos before they are transferred to the mothers. Hence, the environmental conditions inside the chamber should be stable to maintain appropriate growth conditions. The critical factors that affects the conditions inside the incubator includes temperature, gas atmosphere and humidity and these should be well regulated to ensure optimum embryo development.

Esco News • Oct - Dec 2014|12 Medical

Advantages of Miri® GA as compared to conventional validation using a handheld device.

Handheld Device (Conventional Method) Miri® GA

x Separate devices are needed for gas analysis and

temperature measurements.

The Miri® GA can do both gas analysis and temperature measurement.

x Gas analysis and temperature measurements are done in regular interval.

The Miri® GA monitors the gas and temperature constantly.

x Gas suction rate is very harsh at upwards of about 12L/h. Gas suction rate is gentle (and adjustable) at 3L/h.

x No data logging. A data logger, with full features such as adjustable alarm thresholds, comes in standard.

x Can only validate units one at a time. Can monitor up to 6 incubator chambers simultaneously.

Key Benefits:• Unique and easy validation• Online monitoring and alarm notifications• Connect up to 6 incubators

IVF incubators, being a medical device, are different from other laboratory equipment because the risk in resulting to harm is higher. One way to prevent this is through regular validation. Esco understands this need and thus developed a product that can easily validate and monitor each of the factors effectively, the Miri® GA. The Miri® GA is a tabletop device intended to make incubator validation easier and safer. It is capable of monitoring the temperature (PT1000 only) and gas concentrations inside the chambers. It can connect to up to 6 incubators simultaneously and constantly. The Miri® GA has an adjustable flow rate which gives it the ability to properly sample small volume incubation chambers. Moreover, Miri® GA comes with a data logger software which can be helpful in monitoring each of the important parameters. The Miri® GA is perfect to use with Miri® Multiroom Incubator and Miri® TL Time Lapse Incubator.

Miri® GA

Esco News • Oct - Dec 2014 | 13Technology and Innovation

With the recent and constant changes in technology, scientific laboratories feel the need of equipment that can support extensive research and assist them in achieving their goals in the fastest and safest way possible. Esco recognizes these needs and is able to respond to the industry’s requirements. Through the incorporation of the latest innovation and our customers’ recommendations, Esco was able to develop a series of new products designed with superior performance high-lighting energy efficiency and maximum sample protection. These products are the results of Esco’s 35 years of experience in providing laboratory, medical and pharmaceutical equipment solutions.

New products on board

The sun never sets at Esco. As we keep that promise, we are constantly looking for solutions and continuously developing systems and means to easily reach to our customers around the world anytime, anywhere.

With that in mind, Esco launched a Spanish website and is now ready to cater our Spanish speaking clients around the world. The goal with this new site is to provide our visitors with an easier way to learn about our products and services. The design allows the users to quickly navigate product pages, news, videos, customer references, and contact pages. Furthermore, through this site, Esco can communicate to its customers better and in turn provide services faster. We hope that this will yet be another tool to reinforce our business relations with you.

Visit us at http://www.escoglobal.es.

Visit our Spanish website

Esco CO2 incubators are known for its well-rounded sample protection system, and because of its unmatched features, CelCulture® CO2 Incubators have been chosen by many researchers around the world. And as a response to the ever growing needs of the life science industry of reliable laboratory equipment, Esco launched new models of CO2 incubators that guarantee outstanding performance with superb quality.

CelCulture CO2 Incubator with Stainless Steel Exterior

Key features:

Corrosion resistant surface

Meets pharmaceutical and clinical laboratory requirements

Complete contamination control methods

• 90°C Validated Moist Heat Decontamination Cycle

• ULPA Filtration to maintain chamber air at ISO Class 5 condition

• 0.2 micron in-line filter

Easy-to-clean

Easy-to-service

CelCulture® CO2 Incubators

Esco Spanish Website Homepage

CelCulture CO2 Incubator with Stainless Steel Exterior

Esco News • Oct - Dec 2014|14

CelCulture® Water-Jacketed CO2 Incubators

Key features:

More stable temperature control

• Holds temperature longer in the event of power outages

• Better temperature uniformity

Complete contamination control methods

• 90°C Validated Moist Heat Decontamination Cycle

• ULPA Filtration to maintain chamber air at ISO Class 5 condition

• 0.2 micron in-line filter

• ISOCIDE™ antimicrobial coating to eliminate 99.9% of attached bacteria within 24 hours of exposure

Convenient as the unit is equipped with a water fill-in port and drain valve to facilitate cleaning and transfer

Easy monitoring via water level sensor

Technology and Innovation

Spotted on TV!

CelCulture Water-Jacketed CO2 Incubator

As the reporter was checking on the mobile laboratory of Chinese Center for Disease Control and Prevention, Esco BSC, located in the PCR lab, was captured. The mobile lab aims to aid Sierra Leone in their fight against Ebola. This is another confirmation that Esco’s products are truly world-class, worldwide.

Watch video here>>>

Our Airstream® Biosafety Cabinet appeared on CCTV News Channel, the national news platform in China.

Esco News • Oct - Dec 2014 | 15Trainings and Seminars

Our world is now challenged with the spread of Ebola in a number of countries in Africa and a few cases were reported in the USA and Spain. With this, Esco China extended their efforts and held a series of seminars on biosafety and biological safety protection to strengthen the knowledge of those who might be directly exposed to Ebola virus.

Providing quality service training to all our distributors worldwide remains a key focus of Esco. In line with this, Esco held its annual European Distributor Sales and Service Training from 6-10 October 2014 in Giessen, Germany with more than 40 attendees from 15 European countries.

Seminars on biosafety, accomplished by Esco China

European sales and distributor training

These seminars were conducted in Shanxi CDC, Shanxi Railway CDC, Shanxi Medical University, Hebei Medical University, Ruijin Hospital of Shanghai, and Children’s Hospital of Shanghai.

Esco will keep on sharing its expertise on biosafety around China and we will be your ally in fighting against Ebola and other diseases.

Seminars conducted by Esco China

Discussions during the training Products presented during the training

End user seminar conducted by Esco China

Hebei Medical University

Esco News • Oct - Dec 2014|16 Trainings and Seminars

Among the key highlights of the event include the launching of our latest Airstream® Plus Class II Cabinet which has successfully completed independent certification by TUV Nord. The cabinet boasts state-of-the-art energy saving features such as LED lighting and dual ECM/DC Fans. Esco also introduced its latest and most sophisticated CO2 incubator known as the Celsafe® CO2 Incubator, which amongst other outstanding features, has high temperature decontamination at 200°C. Another product that was well received was Esco’s new Lexicon® II ULT Freezer, a very user friendly, quiet and which has one of the best technical performances in the industry.

Esco believes that seminars and trainings worldwide are highly important to keep providing the best quality service. With this, an annual meeting with South American distributors was held on 10-14 November 2014 in Bogota, Colombia. We met distributors from countries with great opportunities like Brazil, Colombia, Bolivia, Chile, Trinidad, El Salvador and Ecuador. It has been our chance to communicate company updates relating to Marketing & Sales strategy for 2015 as well as our targets for the next period.

South America distributors trainings

New innovations like the Versati® Centrifuges, or the brand new CO2 Incubator CelSafei® were introduced. CelSafei® attracted many with its sophisticated design and outstanding features especially its High Temperature Decontamination feature at 200°C. The Generation 3 airflow products such as Airstreami® Biological Safety Cabinets and Laminar Flow Cabinets were also presented.

The attendees also actively participated in our technical service training conducted by one of Esco’s more experienced technical support manager, Kenny Chee.

Esco’s performance in South America remains with a constant growth. We are proud to work closely with our distributors in this market. We have an immense confidence that next year, as one, we will meet our set objectives and fulfill our missions together.

The attendees also actively participated in our technical service training conducted by Esco’s factory-based engineers.

We would like to thank all the participants of this event and we look forward to our next training in 2015.

Biosafety cabinets presented during the training

Hands-on training

Discussions during the training Hands-on Training

Esco News • Oct - Dec 2014 | 17

“Thank you for your hospitality last week. The two days were very informative and will hopefully help us grow Esco sales!” Cian Murphy, Medical Supply Company.

The first group of dealers took part in Esco GB’s first ever dealer training in Esco’s new state of the art premises informing first-hand about new product developments and Esco’s plans for 2015.

Being closer than ever to customers and channel partners, the Esco GB team is looking to honour long-time relationships by offering trainings and seminars at the new location in Barnsley, just off the M1. The first training was held 4-9 December, more are demanded and will be announced January 2015.

The first training covered Esco’s broad product range of high quality clean air and biosafety cabinets, incubators, freezer as well as a briefing on commissioning & testing of cabinets, future marketing plans, and the operations side at Esco GB.

Esco is now operating their own hub and warehouse in Barnsley to meet the increasing demand of high quality laboratory equipment in UK and Ireland.

Knowing the importance of after sales support, Esco decided to invest in an own dedicated service engineer. Together with approved service partners Esco ensures high quality and on time servicing of equipment throughout the UK.

Trainings and Seminars

Esco GB Ltd hosted the 2014 training at its new premises in Barnsley

Esco officers together with distributors during the training

Hands-on training Discussions during the training

Esco News • Oct - Dec 2014|18 Events

It is our pride to share Esco’s expertise on biosafety and biosecurity in the 2nd Annual Conference held on November 29, 2014. The daylong seminar was organized by BBBA at the Microbiology Department of Dhaka University and attended by local and foreign scientists, teachers and researchers.

Lim Lay Yew, Chairman of Esco Group of Companies, gave a very informative lecture entitled “Biosafety and Biosecurity in Different Sectors, Esco 4P Framework and How to Achieve Them”. The lecture aims to enlighten the audience about how can we achieve the 4P Framework by Attitude, Communication, Competence, Commitment and Growth (ACCCG). The 4P Framework being; Prevention of Entry/Exit, Prevention of Generation, Purging, and Personnel Control and Management; to reduce or eliminate the risks of epidemics or threat to public health, safety and security.

In the November 30 issue of The Daily Star, a newspaper in Bangladesh, the highlights of the program were featured concentrating on how biosafety can fight spread of infectious diseases.

Here are some excerpts from the article:

The concepts of biosafety, biosecurity, and biorisk management are new in Bangladesh, but they have enormous importance in the present-day

world in fighting the spread of infectious and giving safety to laboratory workers, experts said at a seminar yesterday.

Biological agents including bacteria, viruses, fungi, and toxins cause infection, allergy, toxicity or other hazards to human health and also pose threats

to economic development, social stability and even national security, said Dr. Asadulghani, President of Bangladesh Biosafety & Biosecurity Association

(BBBA), while presenting his keynote paper. Biosafety and biosecurity are defined as defenses against biorisks, or as the containment principles,

technologies and practices to prevent unintentional exposure to pathogens and toxins, or their accidental release and the protection of valuable

biological materials within laboratories, to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release.

Referring to the recent outbreak of Ebola Virus Disease, Dr. Be Nazir Ahmed, Director (Disease Control) at the Directorate General of Health Services

said, “Though we are far away from the origin of EVD, we and the whole world are under threat”. This type of threat can be faced with biosafety and

biosecurity, he added.

Esco values health the most, thus we support biosafety awareness seminars and conduct our own programs as well, to spread the knowledge and share our expertise on biosafety around the world.

Furthermore, we are continuously developing and improving our containment products to ensure the every laboratory will be equipped with the most efficient and safest product. Our biological safety cabinets will protect the scientists, researchers, and everybody working in the lab from biohazards.

We must act together to fight not only Ebola Virus Disease, but all infectious diseases that threaten the public; and by providing state-of-the-art containment products, and by doing biosafety awareness programs, Esco becomes the world’s partner in the battle against any infectious disease.

Esco strengthens biosafety and biosecurity awareness in Bangladesh

Lim Lay Yew sharing his expertise on Biosafety and Biosecurity in Bangladesh Lim Lay Yew as Guest of Honor

Esco News • Oct - Dec 2014 | 19Events

Esco is committed in delivering cutting-edge products to uphold its promise of meeting each customer’s needs and even exceeding their expectations by continuous product research and development. Esco wants to ensure that in every type of science research, there is an Esco product that supports and boosts its success. This quarter, Esco actively participated in various conferences and trade shows around the world and revealed its most advanced systems to guarantee that every laboratory would benefit from the safe and reliable features that each product offers.

Esco Medical would like to thank our visitors at ASRM held on October 20-22, 2014.

The show has been great where we got to present our products. The Miri® Multiroom Incubator, Fertilisafe™ Multizone IVF Workstation and Miri® TL Time Lapse Incubator were displayed and gained attention from several attendees.

It has been a great opportunity to show the improvement in the system of the Miri® TL. Its unique features have been added with MiriContrast, a system which provides much clearer images; absolutely the best images in the market for time lapse systems. Furthermore, the software has been updated with a fantastic summary and comparison pages with fully flexible annotation parameters to suit every fertility clinic’s requirements.

Expect that Esco Medical will continue to improve each product and develop new ones as a response to the continuous changes in the needs of our clients.

We look forward to the next ASRM event. See you again in 2015!

Esco China actively participated in conferences to make sure that every laboratory is aware of the best products in the market.

Analytica China was held on September 24-26, 2014 at Shanghai New International Exhibition Center; where we exhibited our newest products such as Versati® Centrifuges, Orbicult™ Shakers, and HP Series Laboratory Freezers and Refrigerators. To our great delight the visitors showed great interest in these latest products. Meanwhile, our General Purpose Platform Isolators also received compliments from our visitors in China-Pharm 2014 that was held on October 28-31 at Shenzhen Convention and Exhibition Center.

Uncovering research solutions across the globe

ASRM 2014

Esco at Analytica China and China-Pharm 2014

ASRM is a multidisciplinary organization dedicated to the advancement of the science and practice of reproductive medicine. The Society accomplishes its mission through the pursuit of excellence in education and research and through advocacy on behalf of patients, physicians, and affiliated health care providers. The Society is committed to facilitating and sponsoring educational activities for the lay public and continuing medical education activities for professionals who are engaged in the practice of and research in reproductive medicine.

Source: http://www.asrm.org

Better image by MiriContrast System

SummaryView2

Old Image

Esco News • Oct - Dec 2014|20

Together with our distributor, Vizamed Plus, Esco exhibited at the 6th KARM meeting in Almaty, Kazakhstan onNovember 7-8, 2014.

Just before the main congress, Esco hosted a fantastic pre-congress workshop, attended by participants from Kazakhstan and Kyrgyzstan, at the IRM clinic in cooperation with Vizamed Plus and Research Instruments. Esco Medical products received a lot of compliments as the attendees are very interested of having to work with the units in the future.

Esco Medical is actively visiting each country aiming to bring the market’s best IVF products to every fertility clinic in the world. As for now, we are hoping to serve even more clients in Kazakhstan and Kyrgyzstan.

Events

Expect that Esco will continue innovating high quality products that will respond to the needs of the life science and pharmaceutical industries around the world. We look forward to seeing you again next year!

Esco at the 6th KARM meeting

China-Pharm 2014

Performances during the 6th KARM meeting Visitors during the 6th KARM meeting

Products displayed at China-Pharm 2014

Esco News • Oct - Dec 2014 | 21Events

Medica is the world’s largest trade fair for medicine and medical technology. Held on November 12-15, 2014 at DÜsseldorf, Germany, it is still one of the most important health care events in Europe. This year, approximately 130,000 visitors from different countries participated.

Esco, being the leading provider of laboratory equipment, exhibited in the event and made sure that our products, especially the new ones, reach every laboratory in the world. It has been an opportunity for business where we got leads and distributor visits. The visitors were able to get a glimpse of our new Versati® Centrifuges, which gained a lot of attention due to its design and features that makes them highly versatile and reliable. The Lexicon® ULT Freezer with Aalto Controller, Airstream® Biosafety Cabinet, CelSafe® CO2 Incubator and Sublimate® Freeze Dryer are also presented in the booth. We would like to thank all the people who visited us and we are looking forward to seeing you again in the next year’s Medica.

Medica 2014 Meet Esco at the following events:

China Lab Expo 2015March 12-14, 2015Guangzhou, China

The 4th Reproductive MedicineAnnual Meeting March 19-22, 2015Guiyang, China

P-MEC China 2015June 24-26, 2015Shanghai, China

The 17th Chongqing ART ConferenceNovember 2015Chongqing, China

ASRM 2015October 17-21, 2015Baltimore, Maryland, USA

ESHRE 2015June 14-17, 2015Lisbon, Portugal

Nordic IVF-Laboratory Society Copenhagen 2015January 9-10, 2015Copenhagen, Denmark

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Esco booth at Medica 2014

Visitors at Esco booth

Esco booth at Medica 2014

Esco News • Oct - Dec 2014|22 Esco Product Guide

Esco Product Guide

Aseptic ContainmentIsolators (ACTI)

Weighing & Dispensing Containment Isolators (WDCI) Downflow BoothsGeneral Processing

Platform Isolator (GPPI)

Fume Hoods

CO2 Incubators Cold Storage Thermal Cyclers

Freeze DryersLaminar Flow Clean BenchesBiological Safety Cabinets

Ductless Fume Hoods

Multi-room Incubators Time Lapse Incubators

IVF Workstations

Esco News • Oct - Dec 2014 | 23Global Network

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