Institut Català d’Oncologia

dCOT study phase 4

Pattern of use, acceptability and perceived risk of

electronic cigarettes: a prospective cohort study

with biomarkers

Jose M Martínez-Sánchez, PhD, MPH, BSc

Tobacco Control Unit | WHO Collaborating Center for Tobacco Control

Catalonia Institute of Oncology

Institut Català d’Oncologia

- In 2003, Hon Lik invented the e-cigarette

- During the first years, e-cigs were only available online

- During 2012-2013 the specialized shops of e-cigs proliferated around the world

Institut Català d’Oncologia

«don’t kill the enemy of our enemy»

Jean-François Etter

Institut Català d’Oncologia

Simple search in the PubMed:

(“e-cigarettes” [ti] OR “electronic cigarettes” [ti] OR e-cig* [ti] OR electronic cig* [ti] OR electronic nicotine delivery system [ti])

908 references, of them 509 have an abstract (56%)

Institut Català d’Oncologia

dCOT studies

2004-05 2013-14

Law 28/2005 Law 42/2010

2011-12 2016-17

dCOT4

Institut Català d’Oncologia

dCOT-4

cohort of e-cigarette users

Institut Català d’Oncologia

1) To identify the pattern of use of electronic cigarettes in the cityof Barcelona.

2) To describe the perception of risk and motivation for using the electronic cigarettes.

3) To analyze the influence of electronic cigarettes on the consumption of conventional tobacco according to the users' characteristics and their pattern of use.

4) To characterize the levels of propylene glycol and main metabolite (propylene glycolglucuronic) in urine and saliva of users of electronic cigarettes.

5) To compare the levels of nicotine, cotinine and carcinogens inurine and saliva of users of electronic cigarettes with a sampleof conventional tobacco smokers.

Objectives

Institut Català d’Oncologia

Methods

We will recruit a representative sample of adult (≥18 years old) e-cigarette users of the city of Barcelona (n=720)

We will follow them up 6 and 12 months after the recruitment

6.5% ever e-cigarettes users: 1.6% current users, 2.2% past users, and 2.7 experimentation with e-cigarettes

25,600 e-cigarette users in the city of Barcelona

Institut Català d’Oncologia

Institut Català d’Oncologia

Contents of the questionnaire

-Socio-demographic questions

-Use of conventional cigarettes and other types of tobacco

-Characteristics of use (brand, nicotine, flavor, ml per week, etc)

-Health effects

-Motivation to use electronic cigarettes

-Perception of usefulness and harmfulness of e-cigarettes

-Support to e-cigarette regulation and use of e-cigarettes in different venues

Institut Català d’Oncologia

Tobacco Control Unit

Thanks