day 5 - kuliah heat stroke

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    HE T STROKEI Made Susila Utama

    Tropical & Infectious Disease DivisionInternal Medicine Dept, Medical Faculty

    Sanglah Hospital, Udayana Univ. Bali

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    Severe form of heat illness

    Heat Stroke is A MEDICAL EMERGENCY!

    life-threatening illness commonly fatal

    preventable

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    DEFINITION

    Heat strokeis defined clinically as a core

    body temperature that rises above 40C

    and that is accompanied by hot, dry skin

    and central nervous system abnormalities

    such as delirium, convulsions, or coma.

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    HYPERTHERMIA: A rise in body

    temperature above the hypothalamic set

    point when heat-dissipating mechanisms

    are impaired (by drugs or disease) or

    overwhelmed by external (environmental

    or induced) or internal (metabolic) heat

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    HEAT EXHAUSTION: Mild-to-moderate

    illness due to water or salt depletion thatresults from exposure to high

    environmental heat or strenuous physical

    exercise; signs and symptoms includeintense thirst, weakness, discomfort,

    anxiety, dizziness, fainting, and headache;

    core temperature may be normal, belownormal, or slightly elevated (>37C but

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    Classi f icat ion

    exertional: typically seen in healthy youngadults who overexert themselves in high

    ambient (Surrounding) temperatures or in a hot

    environment to which they are not acclimatized(To adapt).

    non-exertional (classic): usually affects elderly

    and debilitated patients with chronic underlyingdisease. Result of impaired thermoregulation

    combined with high ambient temperatures.

    Often due to impaired sweating6

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    Mortality related to high temperature

    Centers for DiseaseControl (CDC)

    1999 to 20033442

    Heat-Related Fatalities

    in USA.

    approximately 690

    deaths per year

    The fatalities

    males

    elderly

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    Predispos ing factors

    Increased heat production

    - hyperthyroidism

    - exercise

    - sepsis

    8

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    Impaired heat loss -Impaired sweating

    Drugs

    - anticholinergics, anti-Parkinsonian drugs,

    anti-histamines, butyrophenones,

    phenothiazines, tricyclics

    Abnormal sweat glands

    - sweat gland injury following acute heatstroke, barbiturate poisoning

    - cystic fibrosis

    - healed thermal burn salt and water depletion

    - diuretic induced

    Hypokalemia 9

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    Impaired voluntary mechanisms

    coma

    physical disabilitymental illness

    10

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    Others

    - elderly- high ambient temperature and

    humidity, poor ventilation

    - lack of acclimatization- obesity

    - fatigue

    - DM- malnutrition

    - alcoholism

    12

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    Pathophysiology

    Balance

    conduction

    convection

    radiation Evaporation

    Heat Balance equation

    Body Heat = Metabolism

    + [+conduction + radiation]

    + convectionevaporation

    Body Heat = M + [+ K + R + C E]

    Copyright Texas Parks & Wildlife Department

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    Pathophysiology (cont.)

    Physiologic response to heat

    Anterior hypothalamus CNS stimulation vasomotor tone, cutaneous blood flow.

    Increased heart rate and cardiac out put.

    Parasimpatis stimulation sweathing

    Dehydration

    - Adaptation

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    Clinical Manifestation

    Heatstroke

    Trias

    Temp > 40.50 C (104.90)

    Disfungsi CNS Anhidrosis

    Hyperpyrexia: possibility heatstroke after

    exclusion the other cause.

    Many neurological disturbance

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    Clinical manifestation (cont.)

    Heatstroke Effect to system organ

    CNS

    Iritabilitas,

    Combativeness

    Cerebellum

    Sensitif thd panas

    Ataxia

    Cerebral edema

    Anhidrosis

    total failure of thermoregulation

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    Symptoms of heat stroke include

    the following: absence of sweating

    red or flushed skin

    shortness of breath

    rapid pulse hallucinations

    confusion

    agitation

    disorientation seizure

    coma

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    Core Body Temperature

    Use rectal thermometer

    Heat exhaustion

    temp < 104

    Heat Stroke

    temp >= 104

    T > 104 by itself is NOT diagnostic of heat

    strokeAbnormality CNS

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    Invest igat ions

    temperature- electrolytes, urea, creatinine, calcium

    - LFTs

    - CPK

    - ABG: note that Paco2 and Pao2 will be falsely lowand pH falsely elevated if results are not corrected

    for temperature

    - ECG and ECG monitoring

    - urine output- FBC, clotting, fibrinogen, FDP, D-dimer. Anaemia

    frequent. Platelets low/normal. Lymphocytosis

    - test urine for myoglobin22

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    treatment

    Heatstroke

    Treatment

    Initial ABCs, O2high dose

    pulse oximetry

    EKG, IV access, volume replacement

    Temperature

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    treatment (cont.)

    Heatstroke

    Cooling

    Techniques

    Evaporative

    Immersion

    Ice packing

    Strategic ice packs

    Gastric lavage

    Peritoneal lavage

    Cardiac bypass

    H t t k T t t

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    Heatstroke Treatment:

    Cool Quickly!

    External cooling

    -Cold ice packs

    -Water spraying

    -Fans

    -Cooling blankets

    -Ice bath

    Internal cooling

    -Intravenous fluids

    -Peritoneal lavage

    Antipyretics have no role in the acute treatment of heatstroke

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    Prevention

    AC

    non alkohol

    non caffein

    urine output monitoring

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    Prevention is the BestTreatment

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    Underestimate the seriousness of heat

    illness

    Give the victim medications to reducefever

    Give the victim liquids that contain alcohol

    or caffeine Give anything by mouth if HEAT STROKE

    is suspected

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