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8/12/2016 Melissa I Saul, MS Page 1 of 22 CURRICULUM VITAE Melissa I Saul, MS University of Pittsburgh Business Address: 1216 Kaufmann Building Pittsburgh, PA 15213 Business Phone: (412) 692-2331 Business Fax: (412) 648-9118 Email Address: [email protected] Home Address: 806 Maryland Avenue Pittsburgh, PA 15232 Citizenship: U.S. EDUCATION and TRAINING Undergraduate 1978 - 1981 University of Pittsburgh Pittsburgh, PA BA Political Science Graduate 1983 - 1985 Carnegie-Mellon University Pittsburgh, PA MS Public Policy APPOINTMENTS and POSITIONS Academic 5/1995 - Present School of Health and Rehabiliation Sciences University of Pittsburgh Pittsburgh, PA Adjunct Assistant Professor Health Information Management Non-Academic 7/1985 - 4/1990 Department of Veterans Affairs Washington, D.C. Technical Information Specialist Research and Development 5/1990 - 5/2001 University of Pittsburgh Medical Center Pittsburgh, PA Director, Project Engineering Medical Archival Systems 6/2001 - 6/2013 University of Pittsburgh Pittsburgh, PA Informatics Director School of Pharmacy, Center for Pharmacoeconomics and Outcomes Research 6/2001 - 6/30/2015 University of Pittsburgh Clinical Data Scientist

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Page 1: CURRICULUM VITAE Melissa I Saul, MS Business …8/12/2016 Melissa I Saul, MS Page 1 of 22 CURRICULUM VITAE Melissa I Saul, MS University of Pittsburgh Business Address: 1216 Kaufmann

8/12/2016 Melissa I Saul, MS Page 1 of 22

CURRICULUM VITAE Melissa I Saul, MS

University of Pittsburgh

Business Address:

1216 Kaufmann Building Pittsburgh, PA 15213

Business Phone: (412) 692-2331

Business Fax: (412) 648-9118 Email Address: [email protected] Home Address: 806 Maryland Avenue

Pittsburgh, PA 15232

Citizenship: U.S.

EDUCATION and TRAINING

Undergraduate 1978 - 1981

University of Pittsburgh Pittsburgh, PA

BA Political Science

Graduate 1983 - 1985

Carnegie-Mellon University Pittsburgh, PA

MS Public Policy

APPOINTMENTS and POSITIONS

Academic 5/1995 - Present School of Health and Rehabiliation

Sciences University of Pittsburgh Pittsburgh, PA

Adjunct Assistant Professor Health Information Management

Non-Academic 7/1985 - 4/1990 Department of Veterans Affairs

Washington, D.C. Technical Information Specialist Research and Development

5/1990 - 5/2001 University of Pittsburgh Medical Center Pittsburgh, PA

Director, Project Engineering Medical Archival Systems

6/2001 - 6/2013 University of Pittsburgh Pittsburgh, PA

Informatics Director School of Pharmacy, Center for Pharmacoeconomics and Outcomes Research

6/2001 - 6/30/2015 University of Pittsburgh Clinical Data Scientist

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Pittsburgh, PA Biomedical Informatics

7/1/2015 - Present University of Pittsburgh Pittsburgh, PA

Clinical Data Scientist Medicine

MEMBERSHIP in PROFESSIONAL and SCIENTIFIC SOCIETIES

3/2000 - Present Member, Health Information Management Systems Society

HONORS and AWARDS

2005 Pitt Innovator Award for Licensing of Technology - DeID 2005 Chairman’s Award University of Pittsburgh School of Pharmacy

PUBLICATIONS

Peer-reviewed Publications

1. Happ MB, Seaman JB, Nilsen ML, Sciulli A, Tate JA, Saul M, Barnato AE. The number of mechanically ventilated ICU patients meeting communication criteria. Heart & Lung : The Journal of Critical Care. PMID: 25261939. doi: 10.1016/j.hrtlng.2014.08.010.

2. Schneeweiss S, Carver PL, Datta K, Galar A, Johnson MD, Johnson MG, Marty FM, Nagel J, Najdzinowicz M, Saul M, Shoham S, Silveira FP, Varughese CA, Wilck M, Weatherby L, Auton T, Walker AM. Short-term risk of liver and renal injury in hospitalized patients using micafungin: a multicentre cohort study. The Journal of Antimicrobial Chemotherapy. 2016 Jul 12. PMID: 27407049. doi: 10.1093/jac/dkw225.

3. Weinstock MA, Ferris LK, Saul MI, Geller AC, Risica PM, Siegel JA, Solano FX, Kirkwood JM. Downstream consequences of melanoma screening in a community practice setting: First results. Cancer. 2016 Jul 8. PMID: 27391802. doi: 10.1002/cncr.30177.

4. Vipperla K, Somerville C, Furlan A, Koutrompakis E, Saul M, Chennat J, Rabinovitz M, Whitcomb DC, Slivka A, Papachristou GI, Yadav D. Clinical Profile and Natural Course in a Large Cohort of Patients With Hypertriglyceridemia and Pancreatitis. Journal of Clinical Gastroenterology. 2016 Jun 17. PMID: 27322530. doi: 10.1097/MCG.0000000000000579.

5. Kane-Gill SL, MacLasco AM, Saul MI, Politz Smith TR, Kloet MA, Kim C, Anthes AM, Smithburger PL, Seybert AL. Use of Text Searching for Trigger Words in Medical Records to Identify Adverse Drug Reactions within an Intensive Care Unit Discharge Summary. Applied Clinical Informatics. 2016; 7 (3):660-71. PMID: 27453336. doi: 10.4338/ACI-2016-03-RA-0031.

6. Hedges A, Coons JC, Saul M, Smith RE. Clinical effectiveness and safety outcomes associated with prothrombin complex concentrates. Journal of Thrombosis and Thrombolysis. 2015 Dec 19. PMID: 26685667. doi: 10.1007/s11239-015-1321-4.

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7. Cancer Genome Atlas Network. Genomic Classification of Cutaneous Melanoma. Cell. 2015 Jun 18; 161 (7):1681-96. PMID: 26091043. doi: 10.1016/j.cell.2015.05.044.

8. Lindell KO, Liang Z, Hoffman LA, Rosenzweig MQ, Saul MI, Pilewski JM, Gibson KF, Kaminski N. Palliative care and location of death in decedents with idiopathic pulmonary fibrosis. Chest. 2015 Feb; 147 (2):423-9. PMCID: PMC4314817. PMID: 25187973. doi: 10.1378/chest.14-1127.

9. Donahoe M, Valentine VG, Chien N, Gibson KF, Raval JS, Saul M, Xue J, Zhang Y, Duncan SR. Autoantibody-Targeted Treatments for Acute Exacerbations of Idiopathic Pulmonary Fibrosis. PloS One. 2015; 10 (6):e0127771. PMCID: PMC4470587. PMID: 26083430. doi: 10.1371/journal.pone.0127771.

10. Donahoe M, Valentine VG, Chien N, Gibson KF, Raval JS, Saul M, Xue J, Zhang Y, Duncan SR. Correction: Autoantibody-Targeted Treatments for Acute Exacerbations of Idiopathic Pulmonary Fibrosis. PloS One. 2015; 10 (7):e0133684. PMCID: PMC4508023. PMID: 26193485. doi: 10.1371/journal.pone.0133684.

11. Mohan D, Fischhoff B, Farris C, Switzer GE, Rosengart MR, Yealy DM, Saul M, Angus DC, Barnato AE. Validating a vignette-based instrument to study physician decision making in trauma triage. Medical Decision Making : An International Journal of The Society For Medical Decision Making. 2014 Feb; 34 (2):242-52. PMCID: PMC3948210. PMID: 24125789. doi: 10.1177/0272989X13508007.

12. Dunn MA, Behari J, Rogal SS, O’Connell MR, Furlan A, Aghayev A, Gumus S, Saul MI, Bae KT. Hepatic steatosis in diabetic patients does not predict adverse liver-related or cardiovascular outcomes. Liver International : Official Journal of The International Association For The Study of The Liver. 2013 Nov; 33 (10):1575-82. PMID: 23944954. doi: 10.1111/liv.12285.

13. Angheloiu GO, Saul M, Edelman K, Shah H, Mezu UL, Saba S. Predictors of left ventricular function deterioration in patients with left bundle branch block and ejection fraction >50%. Congestive Heart Failure (Greenwich, Conn.). 2013 Jul; 19 (4):E1-4. PMID: 23586729.

14. Kreys TJ, Fabian TJ, Saul MI, Haskett R, Coley KC. An evaluation of inpatient treatment continuation and hospital readmission rates in patients with bipolar disorder treated with aripiprazole or quetiapine. Journal of Psychiatric Practice. 2013 Jul; 19 (4):288-95. PMID: 23852103.

15. Mohan D, Barnato AE, Rosengart MR, Farris C, Yealy DM, Switzer GE, Fischhoff B, Saul M, Angus DC. Trauma triage in the emergency departments of nontrauma centers: an analysis of individual physician caseload on triage patterns. The Journal of Trauma and Acute Care Surgery. 2013 Jun; 74 (6):1541-7. PMCID: PMC3662028. PMID: 23694885. doi: 10.1097/TA.0b013e31828c3f75.

16. Raina A, Yadav D, Regueiro M, Krasinskas AM, Saul MI, Sapienza DA, Binion DG, Hartman DJ. Mucosal IgG4 cell infiltration in ulcerative colitis is linked to disease activity and primary sclerosing cholangitis. Inflammatory Bowel Diseases. 2013 May; 19 (6):1232-7. PMID: 23619716.

17. Barrie A, Mourabet ME, Weyant K, Clarke K, Gajendran M, Rivers C, Park SY, Hartman D, Saul M, Regueiro M, Yadav D, Binion DG. Recurrent blood eosinophilia in ulcerative colitis is associated with severe disease and primary sclerosing cholangitis. Digestive Diseases and Sciences. 2013 Jan; 58 (1):222-8. PMCID: PMC3530000. PMID: 22855293. doi: 10.1007/s10620-012-2329-7.

18. Furlan A, Aghayev A, Chang CC, Patil A, Jeon KN, Park B, Fetzer DT, Saul M,

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Roberts MS, Bae KT. Short-term mortality in acute pulmonary embolism: clot burden and signs of right heart dysfunction at CT pulmonary angiography. Radiology. 2012 Oct; 265 (1):283-93. PMCID: PMC3447174. PMID: 22993221. doi: 10.1148/radiol.12110802.

19. Sorbero ME, Saul MI, Liu H, Resnick NM. Are geriatricians more efficient than other physicians at managing inpatient care for elderly patients? Journal of The American Geriatrics Society. 2012 May; 60 (5):869-76. PMCID: PMC4864361. PMID: 22587852. doi: 10.1111/j.1532-5415.2012.03934.x.

20. Saligram S, Lo D, Saul M, Yadav D. Analyses of Hospital Administrative Data that Use Diagnosis Codes Overestimate the Cases of Acute Pancreatitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2012 Apr 10. PMCID: PMC3662547. PMID: 22504004.

21. Mehrotra A, Dellon ES, Schoen RE, Saul M, Bishehsari F, Farmer C, Harkema H. Applying a natural language processing tool to electronic health records to assess performance on colonoscopy quality measures. Gastrointestinal endoscopy. 2012 Apr 4. PMID: 22482913.

22. Greenspan S, Nace D, Perera S, Ferchak M, Fiorito G, Medich D, Zukowski K, Adams D, Lee C, Saul M, Resnick N. Lessons learned from an osteoporosis clinical trial in frail long-term care residents. Clinical Trials (London, England). 2012 Apr; 9 (2):247-56. PMCID: PMC3889110. PMID: 22157987. doi: 10.1177/1740774511430516.

23. Glad JA, Brink LL, Talbott EO, Lee PC, Xu X, Saul M, Rager J. The relationship of ambient ozone and PM(2.5) levels and asthma emergency department visits: possible influence of gender and ethnicity. Archives of environmental & occupational health. 2012; 67 (2):103-8. PMID: 22524651.

24. Harkema H, Chapman WW, Saul M, Dellon ES, Schoen RE, Mehrotra A. Developing a natural language processing application for measuring the quality of colonoscopy procedures. Journal of The American Medical Informatics Association : JAMIA. 2011 Dec; 18:i150-6. PMCID: PMC3241178. PMID: 21946240. doi: 10.1136/amiajnl-2011-000431.

25. Kane-Gill SL, Visweswaran S, Saul MI, Wong AK, Penrod LE, Handler SM. Computerized detection of adverse drug reactions in the medical intensive care unit. International journal of medical informatics. 2011 Aug; 80 (8):570-8. PMCID: PMC3139253. PMID: 21621453.

26. Yadav D, Ng B, Saul M, Kennard ED. Relationship of serum pancreatic enzyme testing trends with the diagnosis of acute pancreatitis. Pancreas. 2011 Apr; 40 (3):383-9. PMID: 21283039.

27. Regueiro M, Rodemann J, Kip KE, Saul M, Swoger J, Baidoo L, Schwartz M, Barrie A, Binion D. Physician assessment of ulcerative colitis activity correlates poorly with endoscopic disease activity. Inflammatory Bowel Diseases. 2011 Apr; 17 (4):1008-14. PMID: 20812333. doi: 10.1002/ibd.21445.

28. Dedhia RC, Smith KJ, Weissfeld JL, Saul MI, Lee SC, Myers EN, Johnson JT. Cost-identification analysis of total laryngectomy: an itemized approach to hospital costs. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2011 Feb; 144 (2):220-4. PMCID: PMC3419369. PMID: 21493420.

29. Stamm JA, McVerry BJ, Mathier MA, Donahoe MP, Saul MI, Gladwin MT. Doppler-

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defined pulmonary hypertension in medical intensive care unit patients: Retrospective investigation of risk factors and impact on mortality. Pulmonary circulation. 2011; 1 (1):95-102. PMCID: PMC3198625. PMID: 22034595.

30. Salangsang JA, Harrison LH, Brooks MM, Shutt KA, Saul MI, Muto CA. Patient-associated risk factors for acquisition of methicillin-resistant Staphylococcus aureus in a tertiary care hospital. Infection Control and Hospital Epidemiology. 2010 Nov; 31 (11):1139-47. PMCID: PMC4745888. PMID: 20923281. doi: 10.1086/656595.

31. Eisenberg DP, Wey J, Bao PQ, Saul M, Watson AR, Schraut WH, Lee KK, James Moser A, Hughes SJ. Short- and long-term costs of laparoscopic colectomy are significantly less than open colectomy. Surgical endoscopy. 2010 Sep; 24 (9):2128-34. PMID: 20174941.

32. Lavsa SM, Fabian TJ, Saul MI, Corman SL, Coley KC. Influence of medications and diagnoses on fall risk in psychiatric inpatients. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2010 Aug; 67 (15):1274-80. PMID: 20651318.

33. Lazarev M, Ullman T, Schraut WH, Kip KE, Saul M, Regueiro M. Small bowel resection rates in Crohn’s disease and the indication for surgery over time: experience from a large tertiary care center. Inflammatory Bowel Diseases. 2010 May; 16 (5):830-5. PMID: 19798731. doi: 10.1002/ibd.21118.

34. Noschese ML, DiNardo MM, Donihi AC, Gibson JM, Koerbel GL, Saul M, Stefanovic-Racic M, Korytkowski MT. Patient outcomes after implementation of a protocol for inpatient insulin pump therapy. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2009 Jul; 15 (5):415-24. PMID: 19491071.

35. Harbrecht BG, Delgado E, Tuttle RP, Cohen-Melamed MH, Saul MI, Valenta CA. Improved outcomes with routine respiratory therapist evaluation of non-intensive-care-unit surgery patients. Respiratory care. 2009 Jul; 54 (7):861-7. PMID: 19558737.

36. Noschese ML, Dinardo MM, Donihi AC, Gibson JM, Koerbel GL, Saul M, Stefanovic-Racic M, Korytkowski MT. Patient Outcomes Following Implementation of a Protocol for Inpatient Insulin Pump Therapy. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2009 May 6; 1-15. PMID: 19454384.

37. Curry SR, Marsh JW, Shutt KA, Muto CA, O’Leary MM, Saul MI, Pasculle AW, Harrison LH. High frequency of rifampin resistance identified in an epidemic Clostridium difficile clone from a large teaching hospital. Clinical Infectious Diseases : An Official Publication of The Infectious Diseases Society of America. 2009 Feb 15; 48 (4):425-9. PMCID: PMC2819169. PMID: 19140738. doi: 10.1086/596315.

38. Coley KC, Saul MI, Seybert AL. Economic burden of not recognizing panic disorder in the emergency department. The Journal of Emergency Medicine. 2009 Jan; 36 (1):3-7. PMID: 17933481. doi: 10.1016/j.jemermed.2007.06.002.

39. Coley KC, Fabian TJ, Kim E, Ammerman DK, Scipio TM, Saul MI, Kim MS, Whitehead R, Ganguli R. Predictors of aripiprazole treatment continuation in hospitalized patients. The Journal of clinical psychiatry. 2008 Sep; 69 (9):1393-7. PMID: 19012819.

40. Valko M, Cooper G, Seybert A, Visweswaran S, Saul M, Hauskrecht M. Conditional anomaly detection methods for patient-management alert systems. Proceedings of

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The ... International Conference on Machine Learning. International Conference on Machine Learning. 2008 Jul; 2008. PMCID: PMC4226137. PMID: 25392850.

41. Handler SM, Hanlon JT, Perera S, Roumani YF, Nace DA, Fridsma DB, Saul MI, Castle NG, Studenski SA. Consensus list of signals to detect potential adverse drug reactions in nursing homes. Journal of The American Geriatrics Society. 2008 May; 56 (5):808-15. PMCID: PMC2695658. PMID: 18363678.

42. Wadhwa R, Fridsma DB, Saul MI, Penrod LE, Visweswaran S, Cooper GF, Chapman W. Analysis of a failed clinical decision support system for management of congestive heart failure. AMIA Annual Symposium; 2008. p.773-7.

43. Handler SM, Hanlon JT, Perera S, Saul MI, Fridsma DB, Visweswaran S, Studenski SA, Roumani YF, Castle NG, Nace DA, Becich MJ. Assessing the performance characteristics of signals used by a clinical event monitor to detect adverse drug reactions in the nursing home. AMIA Annual Symposium; 2008. p.278-82.

44. Handler SM, Altman RL, Perera S, Hanlon JT, Studenski SA, Bost JE, Saul MI, Fridsma DB. A systematic review of the performance characteristics of clinical event monitor signals used to detect adverse drug events in the hospital setting. Journal of the American Medical Informatics Association : JAMIA. 2007 Jul; 14 (4):451-8. PMCID: PMC2244905. PMID: 17460130.

45. Watson K, Seybert AL, Saul MI, Lee JS, Kane-Gill SL. Comparison of patient outcomes with bivalirudin versus unfractionated heparin in percutaneous coronary intervention. Pharmacotherapy. 2007 May; 27 (5):647-56. PMID: 17461699. doi: 10.1592/phco.27.5.647.

46. Zgibor JC, Orchard TJ, Saul M, Piatt G, Ruppert K, Stewart A, Siminerio LM. Developing and validating a diabetes database in a large health system. Diabetes research and clinical practice. 2007 Mar; 75 (3):313-9. PMID: 16934906.

47. Bové MJ, Jabbour N, Krishna P, Flaherty K, Saul M, Wunar R, Rosen CA. Operating room versus office-based injection laryngoplasty: a comparative analysis of reimbursement. The Laryngoscope. 2007 Feb; 117 (2):226-30. PMID: 17204989. doi: 10.1097/01.mlg.0000250898.82268.39.

48. Kane-Gill SL, Seybert AL, Lazar J, Shatzer MB, Saul MI, Kirisci L, Murali S. Resource use in decompensated heart failure by disease progression categories. Congestive heart failure (Greenwich, Conn.). 2007 Jan; 13 (1):22-8. PMID: 17268207.

49. Weisbord SD, Chen H, Stone RA, Kip KE, Fine MJ, Saul MI, Palevsky PM. Associations of increases in serum creatinine with mortality and length of hospital stay after coronary angiography. Journal of The American Society of Nephrology : JASN. 2006 Oct; 17 (10):2871-7. PMID: 16928802.

50. Donihi AC, Raval D, Saul M, Korytkowski MT, DeVita MA. Prevalence and predictors of corticosteroid-related hyperglycemia in hospitalized patients. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2006 Jul; 12 (4):358-62. PMID: 16901792.

51. Siminerio LM, Piatt GA, Emerson S, Ruppert K, Saul M, Solano F, Stewart A, Zgibor JC. Deploying the chronic care model to implement and sustain diabetes self-management training programs. The Diabetes educator. 2006 Mar; 32 (2):253-60. PMID: 16554429.

52. Gunnerson KJ, Saul M, He S, Kellum JA. Lactate versus non-lactate metabolic

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acidosis: a retrospective outcome evaluation of critically ill patients. Critical Care (London, England). 2006 Feb; 10 (1):R22. PMCID: PMC1550830. PMID: 16507145.

53. Coons JC, Seybert AL, Saul MI, Kirisci L, Kane-Gill SL. Outcomes and costs of abciximab versus eptifibatide for percutaneous coronary intervention. The Annals of pharmacotherapy. 2005 Oct; 39 (10):1621-6. PMID: 16105872.

54. Muto CA, Pokrywka M, Shutt K, Mendelsohn AB, Nouri K, Posey K, Roberts T, Croyle K, Krystofiak S, Patel-Brown S, Pasculle AW, Paterson DL, Saul M, Harrison LH. A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use. Infection Control and Hospital Epidemiology. 2005 Mar; 26 (3):273-80. PMID: 15796280. doi: 10.1086/502539.

55. Hravnak M, Hoffman LA, Saul MI, Zullo TG, Cuneo JF, Pellegrini RV. Short-term complications and resource utilization in matched subjects after on-pump or off-pump primary isolated coronary artery bypass. American Journal of Critical Care : An Official Publication, American Association of Critical-Care Nurses. 2004 Nov; 13 (6):499-507; discussion 508. PMCID: PMC3655795. PMID: 15568655.

56. Gupta D, Saul M, Gilbertson J. Evaluation of a deidentification (De-Id) software engine to share pathology reports and clinical documents for research. American journal of clinical pathology. 2004 Feb; 121 (2):176-86. PMID: 14983930.

57. Weisbord SD, Bruns FJ, Saul MI, Palevsky PM. Provider use of preventive strategies for radiocontrast nephropathy in high-risk patients. Nephron. Clinical practice. 2004; 96 (2):c56-62. PMID: 14988599.

58. Weber RJ, Kane SL, Oriolo VA, Saul M, Skledar SJ, Dasta JF. Impact of intensive care unit (ICU) drug use on hospital costs: a descriptive analysis, with recommendations for optimizing ICU pharmacotherapy. Critical care medicine. 2003 Jan; 31:S17-24. PMID: 12544972.

59. Visweswaran S, Hanbury P, Saul M, Cooper GF. Detecting adverse drug events in discharge summaries using variations on the simple Bayes model. AMIA Annual Symposium; 2003. p.689-93.

60. Beddhu S, Zeidel ML, Saul M, Seddon P, Samore MH, Stoddard GJ, Bruns FJ. The effects of comorbid conditions on the outcomes of patients undergoing peritoneal dialysis. The American journal of medicine. 2002 Jun 15; 112 (9):696-701. PMID: 12079709.

61. Hravnak M, Hoffman LA, Saul MI, Zullo TG, Whitman GR. Resource utilization related to atrial fibrillation after coronary artery bypass grafting. American Journal of Critical Care : An Official Publication, American Association of Critical-Care Nurses. 2002 May; 11 (3):228-38. PMCID: PMC3674411. PMID: 12022486.

62. Hravnak M, Hoffman LA, Saul MI, Zullo TG, Whitman GR, Griffith BP. Predictors and impact of atrial fibrillation after isolated coronary artery bypass grafting. Critical Care Medicine. 2002 Feb; 30 (2):330-7. PMCID: PMC3679531. PMID: 11889304.

63. Buchanan BG, Chapman WW, Cooper GF, Hanbury P, Kayaalp M, Ramachandran M, Saul MI. Creating a software tool for the clinical researchers - the IPS system. In: Proceedings of the Annual Syposium of the American Medical Informatics Association; 2002. p.1210.

64. Hravnak M, Hoffman LA, Saul MI, Zullo TG, Cuneo JF, Whitman GR, Clochesy JM, Griffith BP. Atrial fibrillation: prevalence after minimally invasive direct and standard coronary artery bypass. The Annals of Thoracic Surgery. 2001 May; 71 (5):1491-5.

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PMID: 11383788. 65. Cooper GF, Buchanan BG, Chapman WW, Hanbury P, Kayaalp M, Saul MI. IPS: A

system that uses machine learning to help locate patient records for clinical research. In: Proceedings of the Annual Symposium of the American Medical Informatics Association; 2001. p.813.

66. Konety BR, Nguyen TT, Brenes G, Lewis N, Saul M, Nelson JB, Getzenberg RH. Evaluation of the effect of spinal cord injury on serum PSA levels. Urology. 2000 Jul; 56 (1):82-6. PMID: 10869630.

67. Beddhu S, Bruns FJ, Saul M, Seddon P, Zeidel ML. A simple comorbidity scale predicts clinical outcomes and costs in dialysis patients. The American journal of medicine. 2000 Jun 1; 108 (8):609-13. PMID: 10856407.

68. Coley KC, DaPos SV, Saul MI, Branch RA. Outcomes assessment in routine practice: Use of an electronic medical records database. Formulary. 1999; 34 (1):52-57.

69. Harbrecht BG, Moraca RJ, Saul M, Courcoulas AP. Percutaneous endoscopic gastrostomy reduces total hospital costs in head-injured patients. American journal of surgery. 1998 Oct; 176 (4):311-4. PMID: 9817245.

70. Bruns FJ, Seddon P, Saul M, Zeidel ML. The cost of caring for end-stage kidney disease patients: an analysis based on hospital financial transaction records. Journal of the American Society of Nephrology : JASN. 1998 May; 9 (5):884-90. PMID: 9596087.

71. Cooper GF, Buchanan BG, Kayaalp M, Saul M, Vries JK. Using computer modeling to help identify patient subgroups in clinical data repositories. Proceedings / AMIA ... Annual Symposium. AMIA Symposium. 1998; 180-4. PMCID: PMC2232142. PMID: 9929206.

72. Darby JM, Linden P, Pasculle W, Saul M. Utilization and diagnostic yield of blood cultures in a surgical intensive care unit. Critical care medicine. 1997 Jun; 25 (6):989-94. PMID: 9201052.

73. Zenati M, Domit TM, Saul M, Gorcsan J 3rd, Katz WE, Hudson M, Courcoulas AP, Griffith BP. Resource utilization for minimally invasive direct and standard coronary artery bypass grafting. The Annals of Thoracic Surgery. 1997 Jun; 63:S84-7. PMID: 9203606.

74. Watzlaf VJ, Saul M. Using a clinical and financial database in the development and evaluation of clinical pathways--the HIM professional’s role. Journal of AHIMA / American Health Information Management Association. 1996 Oct; 67 (9):80-5. PMID: 10161443.

75. Watzlaf VJ, Saul M. The emerging role of the health information management professional in data quality and analysis of an electronic medical record system. Topics in health information management. 1994 Nov; 15 (2):61-70. PMID: 10138528.

Books, Book Chapters, Monographs

1. Technology, Applications and Security. In: Abdelhak M, Hanken M, editors. Health Information: Management of a Strategic Resource. ( 5th rev. ed. ) . Philadelphia, PA: Elsevier Science, 2015 Mar.

2. Saul M. Technology, Applications and Security. In: Abdelhak M, editor. Health Information: Management of a Strategic Resource 4th Edition. Philadelphia, PA:

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Elsevier Science, 2011 Mar. 3. Saul M. Technology, Applications and Security. In: Abdelhak M, editor. Health

Information: Management of a Strategic Resource 3rd edition. Philadelphia, PA: Elsevier Science, 2007.

4. Saul M. Information Infrastructure, Technology and Applications. In: Abdelhak M, editor. Health Information: Management of a Strategic Resource , Second Edition. Philadelphia, PA: Elsevier Science, 2001.

Published Abstracts

1. Weinstock MA, Ferris L, Saul M, Geller A, Solano FX, Kirkwood JM. Melanoma screening consequences [abstract]. Journal of Investigative Dermatology. 2015 May; 135.

2. Liu M, Grandinetti L, Barrie A, Saul M, Regueiro MD, Swoger JM. Characterization of Disease Course and Treatment in Patients With Inflammatory Bowel Disease and Anti-TNF Induced Psoriasis [abstract]. American Journal of Gastroenterology. 2014 Oct; 109:S505 doi: 10.1038/ajg.2014.287.

3. Govani S, Waljee A, Swoger JM, Saul M, Higgins P. Stop the Scanners! External Validation of Algorithms Predicting Complications in Patients With Crohn’s Disease Presenting to the Emergency Department [abstract]. American Journal of Gastroenterology. 2014 Oct; 109:S485 doi: 10.1038/ajg.2014.287.

4. Yadav D, Saul M, Papachristou GI, Whitcomb DC, Visweswaran S, Dunn MA. EHR Information is Useful to Predict Clinically Relevant Outcomes in Acute Pancreatitis [abstract]. Gastroenterology. 2013 May; 144 (5):S-279.

5. Davar D, Saul M, Tarhini A, Kirkwood J, Tawbi HA. High-dose interleukin-2 (HD IL-2) in the treatment of advanced melanoma: The University of Pittsburgh experience [abstract]. Journal of Clinical Oncology. 2013 May; 31.

6. Visweswaran S, Saul M, Espino JU, Levander J, Swoger JM, Regueiro MD, Dunn MA. Concept Recognition Tool to Identify the Surgical Complications of Crohn’s Disease in Electronic Health Records [abstract]. Gastroenterology. 2013 May; 144 (5):S-641.

7. Clarke K, Kip K, Saul M, Regueiro MD. Colonoscopic Evidence of Active Ulcerative Colitis Leads to Medication Changes in the Majority of Patients [abstract]. American Journal of Gastroenterology. 2012 Oct; 107:S617.

8. Raina A, Yadav D, Regueiro MD, Krasinskas AM, Saul M, Sapienza D, Binion DG, Hartman D. Mucosal IgG4 Cell Infiltration in Ulcerative Colitis (UC) is Linked to Disease Activity and Primary Sclerosing Cholangitis [abstract]. Gastroenterology. 2012 May; 142 (5):S-686.

9. Tomizawa Y, O’Connell MR, Saul MI, Slivka A, Whitcomb DC. Prevalence and Validation of Alcoholism Diagnosis in Chronic Pancreatitis (CP) Patients [abstract]. Gastroenterology. 2012 May; 142 (5):S-462.

10. Dunn MA, Behari J, O’Connell M, Furlan A, Aghayev A, Gumus S, Saul M, Bae KT. Noninvasive Hepatic Fibrosis Scores Predict Liver-Related Outcomes in Diabetic Patients [abstract]. Gastroenterology. 2012 May; 142 (5):S-1016.

11. Patel A, Amity CL, Frydrych LM, Sippel D, Jones D, Goudeau D, Eng H, Kyle D, Saul M, Solomon D, Wisniewski SR, Moreland LW, Levesque M. The 2010 Rheumatoid Arthritis Criteria Versus the 1987 Rheumatoid Arthritis Criteria: Will the Real Criteria Please Stand up! [abstract]. Arthritis and Rheumatism. 2011 Oct; 63

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(10):S48. 12. Patel AM, Moreland LW, Saul M, Wisniewski SR, Levesque M. The Identification of

Rheumatoid Arthritis for Comparative Effectiveness Research Using an Electronic Health Record and Mathematical Modeling [abstract]. Arthritis and Rheumatism. 2011 Oct; 63 (10):S54.

13. Soejima M, Patel A, Goudeau D, Jones DM, Amity C, Frydrych LM, McBride D, Sippel D, Eng H, Kyle D, Saul M, Wisniewski SR, Moreland LW, Levesque M. Effect of Disease Modifying Anti-Rheumatic Drugs (DMARDs) on Anti-CCP2 and Anti-Citrullinated Protein Antibody (ACPA) Levels during Longitudinal Assessments in Rheumatoid Arthritis Patients. [abstract]. Arthritis and Rheumatism. 2011 Oct; 63 (10):S146.

14. Lupash D, Patel A, Amity C, Frydrych L, Sippel D, Jones DM, Goudeau D, Eng H, Kyle D, Saul M, Balasubramani GK, Solomon DH, Wisniewski SR, Moreland LW, Levesque M. Comparison of the Patient-Based Routine Assessment of Patient Index 3 in Usual Care of Rheumatoid Arthritis to the Physician-Based Disease Activity Score-28 Joint Count and Clinical Disease Activity Index [abstract]. Arthritis and Rheumatism. 2011 Oct; 63 (10):S834.

15. Patel A, Amity CL, Frydrych LM, Sippel D, Jones D, Goudeau D, Eng H, Kyle D, Saul M, Solomon D, Wisniewski SR, Moreland LW, Levesque M. Comparison of Rheumatoid Arthritis Patient Characteristics From Randomized Controlled Trials to a Registry Designed for Rheumatoid Arthritis Comparative Effectiveness Research [abstract]. Arthritis and Rheumatism. 2011 Oct; 63 (10):S837.

16. Patel AM, Amity CL, Frydrych L, Sippel D, Jones D, Goudeau D, Eng H, Kyle D, Saul MI, Solomon D, Wisniewski SR, Moreland LW, Levesque M. Do Rheumatoid Arthritis Patients Meeting ACR/European League Against Rheumatism Remission have Improved Functional Ability, Quality of Life and Work Productivity Compared to Those with Low Disease Activity [abstract]. Arthritis and Rheumatism. 2011 Oct; 63 (10):S985.

17. Rizvi S, Clarke K, Schwartz M, Saul MI, Baidoo L. Gastrointestinal and Hepatic Involvement in Sarcoidosis: A Biopsy Proven Cohort [abstract]. Gastroenterology. 2011 May; 140 (5):S-727.

18. Schwarz M, El Mourabet M, Saul MI, Regueiro MD, Baidoo LK, Barrie A, Swoger JM, Dunn MA, Binion DG. The Cost of Inflammatory Bowel Disease Inpatient Care [abstract]. Gastroneterology. 2011 May; 140 (5):S-735.

19. Barrie A, El Mourabet M, Weyant K, Clarke K, Regueiro MD, Yadav D, Saul M, Binion DG. Eosinophilia/Inflammatory Bowel Disease (Eos/IBD): Association with Severe Colitis and Primary Sclerosing Cholangitis [abstract]. Gastroenterology. 2011 May; 140 (5):S-786.

20. Harkema H, Bishehsari F, Dellon E, Saul M, Chapman WW, Farmer CM, Mehrotra A, Schoen RE. Development and Validation of a Natural Language Processing Computer Program to Evaluate the Quality of Colonoscopy Reports [abstract]. Gastroenterology. 2011 May; 140 (5):S-413.

21. Regueiro MD, Clark K, Kip KE, Swoger JM, Saul MI, Barrie A, Schwartz M, Binion DG. Endoscopic Evidence of Active Inflammation Does Not Lead Physicians to Make Medication Adjustments [abstract]. Gastroenterology. 2011 May; 140 (5):S423.

22. Juneja M, Schwartz M, El Mourabet M, Regueiro MD, Harrison J, Barrie A, Saul M. Patterns of Medical Treatment and Polypharmacy in Geriatric Crohn’s Disease

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[abstract]. Gastroenterology. 2010 May; 138 (5):S-689. 23. Abdul-Baki H, Schwartz M, El Mourabet M, Barrie AM, Regueiro MD, Swoger JM,

Saul MI. Causes of Inpatient Mortality in Crohn’s Disease 1989-2009 [abstract]. Gastroenterology. 2010 May; 138 (5):S534-S535.

24. Hashash JG, El Mourabet M, Schwartz M, Saul MI, Baidoo LK, Regueiro MD. Evolving Patterns of Colonic Dysplasia in Inflammatory Bowel Disease (IBD) 1994-2009: Increasing [abstract]. Gastroenterology. 2010 May; 138 (5):S-447.

25. Lindell KO, Hoffman K, Black T, Richards TI, Choi J, Saul M, Kaminski N, Gibson KF. Extent and Impact of Pulmonary Fibrosis in a Regional Health System [abstract]. American Journal of Respiratory and Critical Care Medicine. 2010 May; 181 (1):A2966.

26. Stamm J, Mathier M, Donahoe MP, Saul M, Gladwin MT. Pulmonary Hypertension in the Medical Intenstive Care Unit Populations: Retrospective Investigation of Risk Factors and Impact on Survival [abstract]. American Journal of Respiratory and Critical Care Medicine. 2010 May; 181 (1):A6832.

27. Gadwood E, Swoger JM, Schwartz M, El Mourabet M, Regueiro MD, Dunn MA, Baidoo LK, Barrie AM, Harrison J, Saul MI, Binion DG. Skin Cancer and Inflammatory Bowel Disease: A Tertiary Referral Center Experience [abstract]. Gastroenterology. 2010 May; 138 (5):S-533.

28. Binion DG, Shah MJ, Schwartz M, Regueiro MD, Dunn MA, Baidoo LK, Barrie AM, El Mourabet M, Saul M. Patterns of Infliximab Utilization in Patients Hospitalized with Severe IBD Colitis [abstract]. Gastroenterology. 2010 May; 138 (5):S-695.

29. Wey J, Eisenberg DP, Saul M, Watson AR, Schraut WH, Lee KK, Moser AJ, Hughes SJ. Short and Long Term Costs of Laparoscopic Colectomy Are Significantly Less than Open Colectomy [abstract]. Gastroenterology. 2009 May; 136 (5):A-909.

30. Tawbi HA, Buch SC, Pancoska P, LIN YE, Romkes M, Sobol R, Kirkwood JM, Saul MI. Prediction of response to alkylator-based chemotherapy in metastatic melanoma (MM) using gene expression and promoter methylation signatures [abstract]. J Clin Oncol. 2009; 27.

31. Donihi AC, Gibson J, Fostel L, Lauster CD, Noschese M, DiNardo M, Koerbel G, Curll M, Saul MI, Korytkowski MT. . Impact of a targeted glycemic management service on the general medicine units of an academic medical center. [abstract]. In: American Diabetes Association 68th Scientific Sessions; Abstract # 491-P. Diabetes 2008. 2008 Jun 8 ; San Francisco, CA 2008. 57 (suppl. 1):A146-147.

32. Reider J, Lin H, DiNardo M, Donihi AC, Saul MI, Korytkowski MT. Efficacy of a guideline for treatment of corticosteroid related hyperglycemia in the hospital. [abstract]. In: American Diabetes Association 68th Scientific Sessions; Abstract # 2077-PO. Diabetes 2008. 2008 Jun 7 ; San Francisco, CA 2008. 57 (suppl. 1):A574.

33. Coley K, Fabian T, Kim E, Ammerman D, Scipio T, Saul M, Whitehead R, Ganguli R. Predictors of Aripiprazole Treatment Success in Newly Treated Psychiatric Inpatients [abstract]. 2007; Boca Raton, Florida.

34. Bollinger JE, Coley K, Rea RS, Saul M. Outcomes in patients treated with recombinant human activated protein C at an academic medical center versus the ENHANCE US trial. [abstract]. Critical Care Medicine. 2006; 34 (12):A111.

35. Aggarwal R, Saul M, Chaffin P, Towers AL, Resnick NM, Sheth HS. Identification and prevention of delirium on general medicine floors. [abstract]. Journal of

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General Internal Medicine. 2006; 21:196. 36. Ruppert K, Saul M, Piatt G, Siminerio LM, Orchard TJ, Zgibor JC. Development of

a diabetes registry for a large health system [abstract]. Diabetes. 2005; 54:A611. 37. Marderstein E, Saul M, Hanbury P, Visweswaran S, Cooper GF, Simmons RL. A

sequential text search algorithm is superior to administratively coded data in estimating wound dehiscence as a surgical patient safety indicator [abstract]. Journal of the American College of Surgeons. 2004 Sep; 199 (3):71-72.

38. Hravnak MT, Hoffman LA, Saul MI, Zullo T, Cuneo JF, Pellegrini RV. Comparing resource utilization in matched subjects undergoing standard versus off-pump primary isolated CABG [abstract]. 2004 May 10-11 ; Washington, DC 2004. 342.

39. Resnick NM, Marano A, Saul M, Young D. Does geriatric care really lose money? [abstract]. Journal of the American Geriatrics Society. 2004 May; 52:S1.

40. Bruns FJ, Saul M, Seddon P, Zeidel ML. Inpatient costs for dialysis patients determine total costs of care: Results of a 6 year study [abstract]. Journal of the American Society of Nephrology. 2003 Nov; 14:447A.

41. Bruns FJ, Saul M, Seddon P, Zeidel ML. In-patient costs for peritoneal dialysis patients are less than those for hemodialysis [abstract]. Journal of the American Society of Nephrology. 2003 Nov; 14:448A.

42. Hravnak MT, Hoffman LA, Saul M, Zullo T, Cuneo JF, Cuneo JF, Pellegrini R. Standard versus off-pump primary isolated CABG: comparison of complications in a matched sample. [abstract]. Critical Care Medicine. 2003; 31 (12):A14.

43. Hravnak MT, Hoffman LA, Saul MI, Zullot T, Cuneo JF, Pelligrini RV. Standard versus off-pump primary isolated CABG: comparison of complications in a matched sample [abstract]. Critical Care Medicine. 2003; 31:A14.

44. Buchanan BG, Chapman WW, Cooper GF, Hanbury P, Kayaalp M, Ramachandran M, Saul M. Creating a software tool for the clinical researchers - the IPS system. [abstract]. 2002 Nov 9 ; San Antonio, TX 2002 Nov. 1210.

45. Gupta D, Saul M, Crowley R, Harrison J, Becich MJ, Gilbertson J. An Evaluation of a De-identification Software Engine: Towards Sharing Clinical Documents and Pathology Reports [abstract]. 2002 Nov 1 ; San Antonio, TX 2002.

46. Cooper GF, Buchanan BG, Chapman WW, Hanbury P, Kayaalp M, Saul MI. IPS: A system that uses machine learning to help locate patient records for clinical research. [abstract]. 2001 Nov 3-4 ; Washington, DC 2001 Nov. 813.

47. Hravnak MT, Hoffman LA, Zullo T, Whitman G, Clochesy J, Saul M. Atrial Fibrillation Following Coronary Artery Bypass Grafting: Prevalence, Predictors and Impact [abstract]. Circulation. 2000; 102 (18):II 512.

Other Publications

1. University of Pittsburgh, Office of General Counsel. Software for de-identifying narrative medical documents (De-ID). Type of Work: Computer file. Copyright Registration Number: Txu000945929/2002-09-27.

RESEARCH

Current research support

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Funding Agency: NIH/NCI Grant Number: U01 CA182367-01 Title of Grant: Molecular Risk Stratification for Colonoscopic Surveillance Principal Investigator: Andrew Chan, MD Saul Role on Grant: Co-Investigator Years Inclusive: 8/1/2016 - 7/31/2021 Percent Effort: 10.0 % Total Amount Awarded: $562,843 Funding Agency: NCATS Grant Number: 5 UL1 TR000005-10 Title of Grant: University of Pittsburgh Clinical and Translational Science

Institute Principal Investigator: Steven Reis, MD Saul Role on Grant: Co-Investigator Years Inclusive: 7/1/2015 - 6/30/2016 Percent Effort: 10.0 % Total Amount Awarded: $16,927 Funding Agency: Melanoma Research Alliance Grant Number: NA Title of Grant: Prevention of Melanoma Deaths by Screening a Large

Health System: Benefits and Harms to Patients Principal Investigator: John Kirkwood, MD Saul Role on Grant: Co-Investigator Years Inclusive: 9/1/2014 - 6/30/2016 Percent Effort: 5.0 % Total Direct Costs: $72,661 Total Amount Awarded: $72,661 Funding Agency: National Institute of Mental Health Grant Number: R01 MH100056 01A1 Title of Grant: DBT for Adolescents with Bipolar Disorder Principal Investigator: Tina Goldstein, PhD Saul Role on Grant: Co-Investigator Years Inclusive: 7/1/2014 - 6/30/2019 Percent Effort: 5.0 % Total Direct Costs: $7,848 Funding Agency: NIH/FIC Grant Number: 1 R25 TW009714-01 Title of Grant: eCapacity for Trauma Information Systems and Research

Education (eCATIS) Principal Investigator: Juan Carlos Puyana, MD Saul Role on Grant: Co-Investigator Years Inclusive: 6/1/2014 - 5/30/2017 Percent Effort: 10.0 % Total Direct Costs: $292,401

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Total Amount Awarded: $315,902 Funding Agency: National Instititute of Aging Grant Number: 5P30AG024827-10 Title of Grant: Pittsburgh Older Americans Independence Center Principal Investigator: Susan Greenspan, MD Saul Role on Grant: Co-Investigator Years Inclusive: 1/1/2014 - 8/31/2018 Percent Effort: 1.5 % Total Direct Costs: $1,200 Total Amount Awarded: $1,700 Funding Agency: Agency for Healthcare and Quality Grant Number: 1R01CA168959-01A1 Title of Grant: Measuring and Improving Colonoscopy Quality using Natural

Language Processing Principal Investigator: Ateev Mehrotra Saul Role on Grant: Co-Investigator Years Inclusive: 10/1/2013 - 9/30/2017 Percent Effort: 3.0 % Total Amount Awarded: $148,325 Funding Agency: NIH/NCI Grant Number: P50 CA121973-06 Title of Grant: SPORE in Skin Cancer Principal Investigator: John Kirkwood, MD Saul Role on Grant: Co-Investigator Years Inclusive: 8/1/2013 - 7/31/2018 Percent Effort: 10.0 % Total Direct Costs: $89,324 Total Amount Awarded: $110,537 Funding Agency: NIH/NINR Grant Number: 1R01-NR01391201 Title of Grant: Predicting Patient Instability Noninvasively for Nursing Care

(PPINNC) Principal Investigator: Marilyn Hravnak PhD, RN, ACNP-BC, FCCM, FAAN Saul Role on Grant: Co-Investigator Years Inclusive: 11/4/2012 - 6/30/2016 Percent Effort: 5.0 % Total Amount Awarded: $1,277,013 Funding Agency: Genetech Grant Number: N/A Title of Grant: Rheumatoid Arthritis Comparative Effectiveness Research

(RACER) Longitudinal Extension Study Principal Investigator: Larry Moreland, MD Saul Role on Grant: Co-Investigator

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Years Inclusive: 1/1/2011 - 12/31/2015 Percent Effort: 5.0 % Total Direct Costs: $7,033

Past research support

Funding Agency: Abbvie Title of Grant: Pancreas Center for Excellence Principal Investigator: David Whitcomb, PhD, MD Saul Role on Grant: Co-Investigator Years Inclusive: 7/1/2013 - 3/31/2015 Percent Effort: 20.0 % Total Direct Costs: $32,000 Funding Agency: University of Pittsburgh Health Policy Institute Grant Number: NA Title of Grant: A Pilot Study of Breast MRI: The Variation and

Consequences Principal Investigator: Gretchen Arhendt, MD Saul Role on Grant: Co-Investigator Years Inclusive: 11/1/2012 - 6/30/2014 Percent Effort: 10.0 % Total Direct Costs: $24,000 Total Amount Awarded: $24,000 Funding Agency: NIH/NCI Grant Number: P50 CA121973-04 Title of Grant: Spore in Skin Cancer Principal Investigator: John Kirkwood, MD Saul Role on Grant: Co-Investigator Years Inclusive: 8/1/2012 - 7/31/2013 Percent Effort: 5.0 % Total Direct Costs: $7,848 Funding Agency: NIH/NHLBI Grant Number: 1K12HL109068-02 Title of Grant: PITTSBURGH CAREER DEVELOPMENT PROGRAM IN

EMERGENCY MEDICINE RESEARCH Principal Investigator: Donald Yealy, MD Saul Role on Grant: Staff Years Inclusive: 7/1/2012 - 6/30/2013 Percent Effort: 5.0 % Funding Agency: US Army Medical Research and Materiel Command Grant Number: W81XWH-11-2-0133 Title of Grant: Framework for Smart Electronic Health Record-Linked

Predictive Models to Optimize Care for Complex Digestive

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Diseases Principal Investigator: Michael A. Dunn, MD Saul Role on Grant: Co-Investigator Years Inclusive: 7/1/2011 - 6/30/2014 Percent Effort: 20.0 % Funding Agency: NLM/NIDR Grant Number: 5 T15 LM007059-24 Title of Grant: Pittsburgh Biomedical Informatics Training Program:

Curriculum Supplement Principal Investigator: Crowley, Rebecca Saul Role on Grant: Co-Investigator Years Inclusive: 7/1/2010 - 6/30/2011 Percent Effort: 10.0 % Funding Agency: Agency for Healthcare and Quality Grant Number: 1R01HS018721-01 Title of Grant: Enhancing the Detection and Management of Adverse Drug

Events in the Nursing Home Principal Investigator: Handler, Steven Saul Role on Grant: Staff Years Inclusive: 5/1/2010 - 4/30/2011 Percent Effort: 20.0 % Total Amount Awarded: $1,975,795 Funding Agency: National Heart, Lung and Blood Institute Grant Number: 5R01HL095115 Title of Grant: Identifying CT Imaging Biomarkers Associated with

Prognosis of Pulmonary Embolism Principal Investigator: Bae, Ty Saul Role on Grant: Co-Investigator Years Inclusive: 4/1/2010 - 6/30/2011 Percent Effort: 10.0 % Funding Agency: NATIONAL INSTITUTE OF ARTHRITIS AND

MUSCULOSKELETAL AND SKIN DISEASES Grant Number: 1RC2AR058989 Title of Grant: Randomized observation study of biologic therapy for RA Principal Investigator: Moreland, Larry W Saul Role on Grant: Co-Investigator Years Inclusive: 9/30/2009 - 12/31/2011 Percent Effort: 10.0 % Total Amount Awarded: $1,340,586 Grant Number: 1 U54 RR023506-01 Title of Grant: Center for Clinical and Translational informatics (CCTI) of

the University of Pittsburgh Clinical and Translational Research Institute

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Principal Investigator: Reis, Steven Saul Role on Grant: Staff Years Inclusive: 7/1/2009 - 6/30/2010 Percent Effort: 15.0 % Funding Agency: National Library of Medicine Grant Number: 1 R21 LM009102 01A1 Title of Grant: Evidence Based Anomaly Detection in Clinical Databases Principal Investigator: Milos Hauskrecht, Ph.D. Saul Role on Grant: Staff Years Inclusive: 4/1/2007 - 3/31/2009 Percent Effort: 5.0 % Funding Agency: Public Health Practice Program Office Grant Number: 5 R01 PH000026-03 Title of Grant: Improving Detection of Outbreaks Due to Aerosol Attacks Principal Investigator: William Hogan, M.D. Saul Role on Grant: Staff Years Inclusive: 9/1/2005 - 9/30/2009 Percent Effort: 5.0 % Funding Agency: National Institute of Health, Roadmap/NCRR/University of

Pittsburgh Multidisciplinary Clinical Research Career Development Award

Grant Number: KL2-RR024154 Title of Grant: Using a Clinical Event Monitor to Detect Adverse Drug

Reactions in Long-Term Care Principal Investigator: Kapoor, Wishwa Saul Role on Grant: Staff Years Inclusive: 7/1/2005 - 6/30/2010 Percent Effort: 4.0 % Funding Agency: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE

AND KIDNEY DISEASES Grant Number: 5 R01 DK061451 Title of Grant: NAPS 2 Continuation - Genome Wide Association Study of

Pancreatitis Principal Investigator: Whitcomb, David Saul Role on Grant: Co-Investigator Years Inclusive: 7/1/2002 - 7/30/2011 Percent Effort: 5.0 % Funding Agency: National Cancer Institute Grant Number: UO1 CA91338-01 Title of Grant: A Shared Pathology Informatics Network Principal Investigator: Becich, Michael Saul Role on Grant: Co-Investigator Years Inclusive: 8/1/2001 - 9/30/2006

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Percent Effort: 10.0 %

INVITED PRESENTATIONS

1. Saul MI. Implications of Health Care Reform for Pharmacy. Presented at: 20th Annual Medical Ethics Update 2011 Ethical Issues in Health Care Reform; 2011 Apr 15; Pittsburgh, PA.

2. Saul M. Methodological Issues Associated with the HIPAA Privacy Rule. Presented at: U.S. Department of Human Services Workshop; 2010 Mar 11; Washington, DC.

3. Coley K, Kirisci L, Saul MI, Robbins S, Smith RB. Anemia is Associatied with Adverse Outcomes in Elderly Patients with Chronic Heart Failure. Presented at: 6th Scientific Forum on Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke; 2005 May 14-16; Washington, DC.

4. Falcione B, Capitano B, Saul MI, Paterson DL, Potoski BA. A Retrospective Study of Vancomycin Dosing in Methicillin-Resistant Staphylococcus Aureus Pneumonia. Poster presented at: Eighth Annual Making A Difference in Infectious Diseases Conference; 2005 May; Phoenix, AZ.

5. Benedict N, Seybert A, Saul MI, Rea RS, Kane-Gill SL. Impact of a Computerized Adverse Event Alerting System on Identifying Patients at High Risk for Heparin Induced Thrombocytopenia (HIT). Poster presented at: annual meeting of the American College of Clinical Pharmacy; 2005.

6. Coley K, Saul MI, Kirisci L, Smith RB. Impact of Anemia on Hospitalization and Mortality in Elderly Patients with Chronic Obstructive Pulmonary Disease and Chronic Kidney Disease. Presented at: International Meeting of International Society for Pharmacoeconomics and Outcomes Research; 2004 May 15-19; Arlington, VA.

7. Coley K, Kirisci L, Saul MI, Robbins S, Smith RB. Association of Anemia with Adverse Outcomes in a Geriatric Population. Presented at: 35th Annual Meeting of the American Society of Consultant Pharmacists; 2004; San Francisco, CA.

8. Coley K, Kirisci L, Saul MI, Smith RB. Outcomes of Elderly Subjects with Anemia: Data From the University of Pittsburgh Medical Center. Presented at: Pan-Anemia/Elderly Interim EPI Investigators’ Meeting; 2003 May 8-9; Santa Monica, CA.

9. Coley K, Saul MI, Weisbord SD, Kim J, Kirisci L, Pringle JL. Resource Utilization Trends Among Congestive Heart Failure Patients With or Without Anemia. Presented at: American Heart Association’s Fourth Scientifc Forum on “Quality of care and Outcomes Research in Cardiovascular Disease and Stroke”; 2002 Oct 13-14; Washington,DC.

OTHER PRESENTATIONS

1. Kane-Gill SL, Visweswaran S, Saul MI, Shah J, Wong I, Forsberg EA, Penrod LE, Handler SM. Computerized detection of adverse drug reactions (ADRs) in the medical ICU. Presented at: Society of Critical Care Medicine’s 38th Critical Care Congress; 2009 Jan; Nashville, TN.

2. Handler SM, Hanlon JT, Perera S, Saul MI, Fridsma DB, Visweswaran S,

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Studenski SA, Roumani YF, Castle NG, Nace DA, Becich MJ. Assessing the performance characteristics of signals used by a Clinical Event Monitor to detect adverse drug reactions in the nursing home. Presented at: American Medical Informatics Association Annual Symposium; 2008; Washington, DC.

3. Kane-Gill SL, Visweswaran S, Saul MI, Shah J, Wong I, Forsberg EA, Penrod LE, Handler SM. Computerized detection of adverse drug reactions in the medical ICU. Poster presented at: 37th SCCM Critical Care Congress; 2008; Memphis, TN.

4. Bellamy CJ, Kane-Gill SL, Verrico MM, Saul MI, Handler SM, Weber RJ. . Evaluating the usefulness of triggers to detect adverse drug reactions (ADRs) in the medical intensive care unit (ICU). Presented at: ACCP 2007 Annual Meeting; 2007 Oct; Denver, CO.

5. Handler SM, Hanlon JT, Perera S, Roumani YF, Nace DA, Fridsma DB, Castle NG, Saul MI, Studenski SA. Developing a consensus list of signals to detect potential adverse drug reactions in the nursing home. Poster presented at: National Institutes of Health, Clinical and Translation Sciences K12 Awards Annual Meeting; 2007; Washington, DC.

6. Handler SM, Hanlon JT, Perera S, Roumani YF, Nace DA, Fridsma DB, Castle NG, Saul MI, Studenski SA. Developing a consensus list of signals to detect potential adverse drug reactions in the nursing home. Poster presented at: University of Pittsburgh Department of Medicine 5th Annual Research Day; 2007; Pittsburgh, PA.

7. Handler SM, Hanlon JT, Perera S, Roumani YF, Nace DA, Fridsma DB, Castle NG, Saul MI, Studenski SA. Developing a consensus list of signals to detect potential adverse drug reactions in the nursing home. Poster presented at: University of Pittsburgh’s Clinical and Translational Science Day; 2007; Pittsburgh, PA.

8. Handler SM, Hanlon JT, Perera S, Roumani YF, Nace DN, Fridsma DB, Castle NG, Saul MI, Studenski SA. Developing a consensus list of signals to detect potential adverse drug reactions in the nursing home. Poster presented at: Department of Biomedical Informatics Annual Retreat, Seven Springs; 2007; Champion, PA.

9. Bellamy CJ, Kane-Gill SL, Verrico MM, Saul MI, Handler SM, Weber RJ. Evaluating the usefulness of triggers to detect adverse drug reactions (ADRs) in the medical intensive care unit (ICU). Presented at: The American College of Clinical Pharmacy Annual Meeting; 2007; Denver, CO.

10. Handler SM, Altman RL, Perera S, Hanlon JT, Studenski SA, Saul MI, Fridsma DB. A meta-analysis of the performance characteristics of Clinical Event Monitor signals used to detect adverse drug events in the hospital setting. Poster presented at: Department of Biomedical Informatics Annual Retreat, Seven Springs; 2006; Champion, PA.

11. Handler SM, Altman RL, Perera S, Hanlon JT, Studenski SA, Saul MI, Fridsma DB. A meta-analysis of the performance characteristics of Clinical Event Monitor signals used to detect adverse drug events in the hospital setting. Poster presented at: The First Annual “Celebrating Research on Aging and Building Collaborations for the Future” Meeting, University of Pittsburgh Institute on Aging; 2006; Pittsburgh, PA.

12. Handler SM, Altman RL, Perera S, Hanlon JT, Studenski SA, Saul MI, Fridsma DB. A meta-analysis of the performance characteristics of Clinical Event Monitor signals used to detectc adverse drug events in the hospital setting. Poster

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presented at: University of Pittsburgh Biomedical Graduate Student Association; 2006; Pittsburgh, PA.

13. Seybert A, Kane-Gill SL, Saul MI, Edmundowicz D. Adherence to guidelines for lipid management on admission for unstable angina. Presented at: American College of Clinical Pharmacy Annual Meeting; 2005 Oct; San Francisco, CA.

14. Benedict NJ, Seybert A, Kane-Gill SL, Saul MI. Effects of a computerized adverse event alerting system on patients at high risk for Heparin Induced Thrombocytopenia (HIT). Presented at: American College of Clinical Pharmacy Annual Meeting; 2005 Oct; San Francisco, CA.

15. Zerumsky K, Seybert A, Kane-Gill SL, Saul MI, Lee JS. bivalirudin versus unfractionated heparin in percutaneous coronary intervention: determining outcomes and glycoprotein inhibitor use. Presented at: American College of Clinical Pharmacy Annual Meeting; 2005 Oct; San Francisco, CA.

16. Benedict N, Seybert A, Rea RS, Saul MI, Kane-Gill SL. Effects of a computerized adverse event alerting system on patients at high risk for heparin induced thrombocytopenia (HIT). Poster presented at: ACCP 2005 Annual Meeting; 2005 Oct; San Francisco, CA.

17. Kane-Gill SL, Seybert A, Spates J, Shatzer M, Saul MI, Kirisci L, Murali S. Resource use during hospitalization for acute decompensated heart failure. Poster presented at: ACCP 2005 Annual Meeting; 2005 Oct; San Francisco, CA.

18. Zerumsky K, Seybert A, Saul MI, Lee JS, Kane-Gill SL. Evaluation of clinical outcomes of anticoagulation during percutaneous coronary intervention. Poster presented at: ACCP 2005 Annual Meeting; 2005 Oct; San Francisco, CA.

19. Seybert A, Kane-Gill SL, Saul MI, Edmundowicz D. Adherence to guidelines for lipid management on admission for unstable angina. Poster presented at: ACCP 2005 Annual Meeting; 2005 Oct; San Francisco, CA.

20. Kane-Gill SL, Spates j, Shatzer M, Seybert A, Saul MI, Kirisci L, Murali S. Comparing resource use of right and left sided heart failure. Presented at: 6th ScientificForum on Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke; 2005 May; Washington, DC.

21. Kane-Gill SL, Seybert A, Spates J, Shatzer M, Saul MI, Kirisci L, Murali S. Resource use during hospitalization for acute decompensated heart failure. Presented at: 6th Scientific Forum on Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke; 2005 May; Washington, DC.

22. Seybert A, Kane-Gill SL, Spates J, Shatzer M, Saul MI, Kirisci L, Murali S. Resource use during hospitalization for acute decompensated heart failure. Poster presented at: 6th Scientific Forum on Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke; 2005 May; Washington, D.C.

23. Kane-Gill SL, Shatzer M, Seybert A, Spates J, Saul MI, Kirisci L, Murali S. Comparing resource use of patients with diastolic dysfunction to systolic dysfunction. Presented at: American College of Clinical Pharmacy Spring Meeting; 2005 Apr; Myrtle Beach, SC.

24. Kane-Gill SL, Shatzer M, Seybert A, Spates J, Saul MI, Kirisci L, Murali S. Comparing resource use of patients with diastolic dysfunction to systolic dysfunction. Poster presented at: ACCP Spring Meeting; 2005 Apr; Myrtle Beach,SC.

25. Kane-Gill SL, Seybert A, Coons JC, Saul MI. A comparison of hospital costs by bleeding severity for patients receiving glycoproteins. Presented at: 34th SCCM

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Educational and Scientific Symposium; 2005 Jan; Phoenix, AZ. 26. Kane-Gill SL, Seybert A, Coons JC, Saul MI. A comparison of hospital costs by

bleeding severity for patients receiving glycoproteins. Poster presented at: 34rd SCCM Critical Care Congress; 2005 Jan; Phoenix, AZ.

27. Shullo MA, Weber RJ, Verrico MM, McKaveney T, Saul M, Smith RB, Pater K. An Adverse Drug Event Detection Tool Developed Through Integrating Clinical Information Systems and the Clinical Problem List: Results of a Pilot Program. Poster presented at: ACCP Clinical Meeting; 2001 Oct; Salt Lake City, UT.

28. Shullo MA, Weber RJ, Verrico MM, McKaveny TP, Saul MI, Smith RB, Steinmetz KL. An adverse drug event detection tool developed through interpreting clinical information systems and the clinicalinformation systems and the clinical problem list: results of a pilot program. Poster presented at: American College of Clinical Pharmacy: Spring Practice and Research Forum; 2001 Apr; Salt Lake City, UT.

TEACHING

Graduate Courses

Year(s) Course Number & Title Role 5/9/2016 - 8/13/2016 BIOINF - 2110 - 17995, CONC SOFTWR

PROJ ENGR HLTH CRE Primary Instructor

5/9/2016 - 8/13/2016 HRS - 2428 - 12604, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

5/4/2015 - 8/8/2015 BIOINF - 2110 - 18466, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

5/4/2015 - 8/8/2015 HRS - 2428 - 12739, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

5/5/2014 - 8/9/2014 HRS - 2428 - 12825, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

5/5/2014 - 8/9/2014 BIOINF - 2110 - 18865, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

1/6/2014 - 4/26/2014 BIOINF - 2110 - 26324, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

5/6/2013 - 8/10/2013 BIOINF - 2110 - 19639, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

5/6/2013 - 8/10/2013 HRS - 2428 - 13038, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

5/7/2012 - 8/11/2012 BIOINF - 2110 - 12749, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

5/7/2012 - 8/11/2012 HRS - 2428 - 13218, CONC SOFTWR PROJ ENGR HLTH CRE

Primary Instructor

2002 - Present BIOINF-2110, Software Engineering in Health Care

Instructor

1997 - Present HRS-2428, Software Engineering in Health Care

Instructor

Postgraduate Courses

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Year(s) Course Number & Title Role 1/31/2012 - Present PHARM-3067, Clinical Pharmacy

Environments Instructor

Continuing Education

11/11/2011 - 11/11/2011

Saul M. Public Health Reports (SEER, NIS, NSQIP). 5.0 hrs, Second Annual Thought Leaders Conference on Minimally Invasive Pancreatic Surgery, University of Pittsburgh School of Medicine.

MENTORING AND ADVISING

Doctoral Students

Year(s) Student’s Name & Department/Degree/Discipline

Role

3/1/2007 - 4/1/2008 Joann Glad DPH (4/15/2008) THE USE OF ELECTRONIC MEDICAL RECORDS BASED ON A PHYSICIAN DIAGNOSIS OF ASTHMA FOR COUNTY WIDE ASTHMA SURVEILLANCE

Committee Member

SERVICE

Service to Internal Organizations

UPMC/UPP/VA Committees

2002 - 2010 Member, UPMC Presbyterian Medical Record Committee

Service to External Organizations