Curriculum vitae Kristen E. Frenzel, Ph.D.

Emory University Neuroscience and Behavioral Biology Program 1462 Clifton Rd. NE W: 404-727-1317 Suite 304E C: 678-362-9318 Atlanta, GA 30322 kfrenze@emory.edu Education and Academic Positions: Sept 2015-2018 Associate Director, Neuroscience and Behavior Biology

program, Emory University July 2012-present Senior Lecturer, Neuroscience and Behavior Biology program Emory University 2006-July 2012 Lecturer, Neuroscience and Behavior Biology program

Emory University 2001- 2005 Postdoctoral Fellowship, Department of Pathology

Emory University, Advisor: Kenneth E. Bernstein, M.D. 1991-1994 Research Assistant, Department of Pathology Emory University 2001 Ph.D., Emory University, Advisor: Douglas Falls, M.D.

Program: Biochemistry, Cell, and Developmental Biology Concentration: Molecular Neurobiology Dissertation Title: Biosynthetic Processing of Transmembrane Neuregulins in the Central Nervous System

1991 B.Sc., Georgia Institute of Technology Major: Applied Biology

Teaching and Pedagogy Grants Received: Fall 2016 National Science Foundation: RCN-UBE # 1624104 “RCN-UBE:

The Neuroscience Case Network (NeuroCaseNet)”; co-PI with Pat Marsteller

Fall 2015 CFDE Fund for Innovative Teaching (FIT) grant; co-PI with Leah Roesch

Fall 2014 CFDE Fund for Innovative Teaching (FIT) grant; co-PI with Leah Roesch

Fall 2011 CFDE Classroom Mini Grants recipient (for NBB 120) Fellowships, Awards and Honors: Summer 2016 Invited lecturer for Emory-Tibet Science Initiative Fall 2014-present STEP/Scholarship of Teaching and Learning (SoTL) fellow:

“Assessment of a Flipped Neurobiology course” Fall 2014-present Science Cases Network; co-group leader with Leah Roesch for

national network of neuroscience educators Fall 2014 Invited lecture for the Annual Society for Neuroscience Meeting

Teaching workshop, November 2014: “Flipping the classroom: What do you actually do in class?

Professional Development: Summer 2017 Faculty for Undergraduate Neuroscience (FUN) Teaching

Workshop, Chicago, IL Fall 2016 Emory Tibet Symposium, Mundgod India Summer 2014 Faculty for Undergraduate Neuroscience (FUN) Teaching

Workshop, Ithaca, NY Summer 2014 CFDE Course Development Discussion group Spring 2014 CFDE Pilot Mentoring Program Spring 2013 CFDE Workshop “Student Learning Outcomes Assessment” Summer 2012 STEP/HHMI Faculty Development Institute

Participant and co-Presenter: “Problems and Cases: Adopt and Adapt” (with Pat Marsteller)

Spring 2012 CFDE/ECIT Active Learning and Engagement Initiative Ongoing Science Education Journal Club member Instructional Activities: Courses Developed Spring 2017 NBB 498 Neurobiology for ETSI (Tibetan monks as students) Spring 2013/14 NBB 470 Molecular Mechanisms of Neurodegenerative Disease NBB Paris Program NBB 402 Perspectives in Neuroscience and Behavior-(2013,

2015, 2017) NBB Paris Program NBB 370 Charcot’s Salpetriere Investigations (2011) 2010-present NBB 120 Neuroscience for nonscientists-From Botox to

Behavior 2007-2009 NBB 370/470 Molecular Mechanisms of Neurological Disorders Fall 2009 NBB 190 Freshman seminar: From Botox to Behavior 2006 NBB 190 Freshman seminar: Neuroscience in the News Emory Pre-college Neurology, Drugs and the Media (2009) Program Case Studies in Neuroscience (2011, 2013) Instructional Activities: Courses Taught 2006-2012 NBB 361W Neurobiology Project Lab 2006-present NBB 401W Topics in Neuroscience and Behavior (required) Course director 2011-present 2007-present NBB 301 Introduction to Neurobiology (required) 2007, 2009, 2010 NBB 497W Directed Study Professional Service: National 2016-present Cases Editor for Journal of Undergraduate Neuroscience

Education (JUNE) Professional Service: NBB Program 2015- Associate Director of NBB Program 2012-2013 Chair, Lecture-Track Faculty Hiring Committee 2008-present NBB Executive Committee member 2008-present NBB Summer Study Abroad in Paris, France: Co-Director 2010-present NBB-PACE Liaison

2006-present Honors Theses Committee member for 24 NBB student committees, 1 Economics student committee

Professional Service: Emory College 2016-2017 Ad-Hoc Pedagogy and Curriculum Development committee;

part of strategic planning initiative Summer 2016 StemBassador for STEM Pathways students 2015-2018 Emory College Senate, member 2014-2017 Education Abroad Committee; Chair 2016-2017 2013-2015 Lecture-track faculty (LTF) Executive committee 2012-2015 Academic Standards Committee 2012-2014 Ad-Hoc Campus Life Committee 2010-2016 Pre College Advisory Committee as needed Bobby Jones Fellowship Review Committee 2006-2012 Student Honor Council, Faculty Advisor 2008-2010 Emory Scholars Program, Faculty Advisor Professional Service: Emory University 2013-present Faculty Life Course Committee 2008-2014 Athletics and Recreation Committee; co-Chair 2010-2013 Professional Service: Emory Student Organizations 2009-present Undergraduate Women in Neuroscience (UWIN) Faculty Liaison 2009-present Emory Women in Neuroscience (EWIN), faculty representative 2007 FAME Faculty representative Professional Societies and Community Outreach: 2006, 2012-present Society for Neuroscience member 2011-present Faculty for Undergraduate Neuroscience member Fall 2011 Teaching Brains; Wesley International Academy school visit Publications Teaching and Pedagogy-related: Frenzel KE and Roesch LA (2016) Poster Presentation for the Annual Society for Neuroscience Meeting, November 2016; Quantitative Literacy in Non-Majors Roesch LA, Frenzel K (2016) From Botox to Behavior: Neuroscience for non-scientists at Emory. J Undergrad Neurosci Educ. April 15:15(1) A72-A75. Wiertelak EP, Frenzel KE Roesch LA (2016) Case Studies and Neuroscience Education: Tools for Effective Teaching. J Undergrad Neurosci Educ. Apr 15;14(2):E13-4. Roesch LA, Frenzel K (2016) Nora's Medulla: A Problem-Based Learning Case for Neuroscience Fundamentals. J Undergrad Neurosci Educ. Apr 15;14(2):C1-3. Frenzel KE and Roesch LA (2015) Poster Presentation for the Annual Society for Neuroscience Meeting, October 2015; Science Case Network: Creating a working group for case studies in neuroscience.

Roesch LA and Frenzel KE (2014) Poster Presentation for the Annual Society for Neuroscience Meeting, November 2014; Implementation of active pedagogies in undergraduate neuroscience course for non-majors. Ritter SL, Meyer RC, Frenzel KE (2012) Poster Presentation for the Annual Society for Neuroscience Meeting, October 2012; The use of clinical case studies and written responses to enhance student understanding of scientific concepts in a laboratory course. Laboratory Research Experiences: Frenzel K, Wallace TA, McDoom I, Capecchi MR, Bernstein KE, Sayeski PP. (2006) A functional Jak2 tyrosine kinase domain is essential for mouse development. Exp. Cell Res. Exp Cell Res. Sep 10;312(15):2735-44. Fuchs S, Frenzel K, Hubert C, Lyng R, Muller L, Michaud A, Xiao HD, Adams JW, Capecchi MR, Corvol P, Shur BD, Bernstein KE. (2005) Male fertility is dependent on dipeptidase activity of testis ACE. Nat Med. 2005 Nov;11(11):1140-2. Bernstein KE, Xiao HD, Frenzel K, Li P, Shen XZ, Adams JW, Fuchs S. (2005) Six truisms concerning ACE and the renin-angiotensin system educed from the genetic analysis of mice. Circ Res. 2005 Jun 10;96(11):1135-44 Bernstein KE, Xiao HD, Adams JW, Frenzel K, Li P, Shen XZ, Cole JM, Fuchs S. (2005) Establishing the role of angiotensin-converting enzyme in renal function and blood pressure control through the analysis of genetically modified mice. J Am Soc Nephrol. 2005 Mar;16(3):583-91 Xiao HD, Fuchs S, Frenzel K, Teng L, Li P, Shen XZ, Adams J, Zhao H, Keshelava GT, Bernstein KE, Cole JM. (2004) The use of knockout mouse technology to achieve tissue selective expression of angiotensin converting enzyme. J Mol Cell Cardiol. Jun;36(6):781-9. Xiao HD, Fuchs S, Frenzel K, Teng L, Bernstein KE. (2004) Circulating versus Local Angiotensin II in Blood Pressure Control: Lessons from Tissue-Specific Expression of Angiotensin-Converting Enzyme (ACE). Crit Rev Eukaryot Gene Expr. 14(1-2):137-45. Fuchs S, Frenzel K, Xiao HD, Adams JW, Zhao H, Keshelava G, Teng L, Bernstein KE. (2004) Newly recognized physiologic and pathophysiologic actions of the angiotensin-converting enzyme. Curr Hypertens Rep. 2004 Apr;6(2):124-8. Fuchs S, Xiao HD, Cole JM, Adams JW, Frenzel K, Michaud A, Zhao H, Keshelava G, Capecchi MR, Corvol P, Bernstein KE. (2004) Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice. J Biol Chem. 2004 Apr 16;279(16):15946-53. Xiao HD, Fuchs S, Frenzel K, Cole JM, Bernstein KE. (2003) Newer approaches to genetic modeling in mice: tissue-specific protein expression as studied using angiotensin-converting enzyme (ACE). Am J Pathol. Sep;163(3):807-17.

Frenzel KE and Falls, DL. (2001) Neuregulin-1 Proteins in Rat Brain and Transfected Cells are Localized to Lipid Rafts. Journal of Neurochemistry 76: 1-12. Wang JY, Frenzel KE, Wen D, Falls DL. (1998) Transmembrane Neuregulins Interact with LIM Kinase 1, a Cytoplasmic Protein Kinase Implicated in Development of Visuospatial Cognition. Journal of Biological Chemistry 273: 20525-20534. Esther CR, Thomas KE, and Bernstein KE. (1994) Chicken Lacks the Testis Specific Isozyme of Angiotensin Converting Enzyme found in Mammals. Biochemical and Biophysical Research Communications 205: 1916-1921. Bernstein KE, Shai SY, Howard T, Balogh R, Frenzel K, and Langford K. (1993) Structure and Regulated Expression of Angiotensin Converting Enzyme and the Receptor for Angiotensin II. American Journal of Kidney Disease. 21: Suppl. 1: 53-57. Langford K, Frenzel K, Martin BM, and Bernstein KE. (1992) The Genomic Organization of the Rat AT1 Angiotensin Receptor. Biochemical and Biophysical Research Communications 183: 1025-1032. Laboratory Research Grants Received: 2003-2005 NRSA Individual Postdoctoral Fellowship Department of

Pathology, Emory University 2001-2003 NIH Postdoctoral Training Grant recipient, Department of

Pathology, Emory University 1996-1998 NIH Predoctoral Training Grant recipient, Biochemistry, Cell,

and Molecular Biology Training Grant; Emory University