curriculum vitae june 30, 2013 biographicalcurriculum vitae june 30, 2013 biographical name: charles...

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CURRICULUM VITAE June 30, 2013 BIOGRAPHICAL NAME: Charles A. Jungreis, M.D. ADDRESS: Office TUH Department of Radiology 3401 North Broad Street Philadelphia, PA 19140 Phone 215-707-7237 or 4213 Fax 215-707-9389 Email: [email protected] CURRENT STATUS: Chairman, Department of Radiology Professor of Radiology and Neurological Surgery W. Edward Chamberlain Professor Temple University School of Medicine Philadelphia, PA CURRENT HOSPITAL AFFILIATIONS: Temple University Hospital, Philadelphia, PA Episcopal Campus, TUH, Philadelphia, PA. North Eastern Campus, TUH, Philadelphia, PA. Jeanes Hospital, Philadelphia, PA Fox Chase Cancer Center, Philadelphia, PA

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Page 1: CURRICULUM VITAE June 30, 2013 BIOGRAPHICALCURRICULUM VITAE June 30, 2013 BIOGRAPHICAL NAME: Charles A. Jungreis, M.D. ADDRESS: Office TUH Department of Radiology 3401 North Broad

CURRICULUM VITAE

June 30, 2013 BIOGRAPHICAL NAME: Charles A. Jungreis, M.D. ADDRESS: Office TUH Department of Radiology 3401 North Broad Street Philadelphia, PA 19140 Phone 215-707-7237 or 4213 Fax 215-707-9389 Email: [email protected] CURRENT STATUS: Chairman, Department of Radiology Professor of Radiology and Neurological Surgery W. Edward Chamberlain Professor Temple University School of Medicine Philadelphia, PA CURRENT HOSPITAL AFFILIATIONS: Temple University Hospital, Philadelphia, PA Episcopal Campus, TUH, Philadelphia, PA. North Eastern Campus, TUH, Philadelphia, PA. Jeanes Hospital, Philadelphia, PA Fox Chase Cancer Center, Philadelphia, PA

Page 2: CURRICULUM VITAE June 30, 2013 BIOGRAPHICALCURRICULUM VITAE June 30, 2013 BIOGRAPHICAL NAME: Charles A. Jungreis, M.D. ADDRESS: Office TUH Department of Radiology 3401 North Broad

2CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

EDUCATION AND TRAINING UNDERGRADUATE: SEPTEMBER 1971 - JUNE 1975 Dartmouth College, Hanover, NH B.A. cum laude Distinction in Chemistry GRADUATE: SEPTEMBER 1976 - JUNE 1980 SUNY - Downstate Medical Center (Medical School), Brooklyn, NY M.D. POST GRADUATE TRAINING: JULY 1980 - JUNE 1981 Staten Island Hospital, Staten Island, NY Program Director: Melvin H. Worth, MD Resident, General Surgery JULY 1981 - JUNE 1984 North Shore University Hospital

Cornell Medical Center Program Director: Harold L. Stein, MD Resident, Radiology FEBRUARY - MARCH 1982 Hospital for Special Surgery (six weeks) Bone Radiology Elective Program Director: Robert H. Freiberger, MD APRIL - MAY 1984 Armed Forces Institute of Pathology (six weeks) Radiographic and Pathologic

Correlations Elective JULY 1984 - JUNE 1986 New York University Medical Center

Neuroradiology Fellow Program Director: Irvin I. Kricheff

Page 3: CURRICULUM VITAE June 30, 2013 BIOGRAPHICALCURRICULUM VITAE June 30, 2013 BIOGRAPHICAL NAME: Charles A. Jungreis, M.D. ADDRESS: Office TUH Department of Radiology 3401 North Broad

3CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

APPOINTMENTS AND POSITIONS ACADEMIC: JULY 1985 - JUNE 1986 New York University Medical Center New York, New York Assistant Clinical Professor of Radiology JUNE 1986 - APRIL 1991 University of Pittsburgh School of Medicine, Pittsburgh, PA Assistant Professor of Radiology JULY 1989 - APRIL 1991 University of Pittsburgh School of Medicine Pittsburgh, PA Assistant Professor of Neurological Surgery (secondary appointment) MAY 1991 - MAY 2000 University of Pittsburgh School of Medicine Pittsburgh, PA Associate Professor of Radiology and Neurological Surgery APRIL 2000 – OCTOBER 2003 University of Pittsburgh School of Medicine Pittsburgh, PA Professor of Radiology and Neurological Surgery NOVEMBER 2003 – PRESENT Temple University School of Medicine Philadelphia, PA Professor of Radiology and Neurological Surgery Chairman Department of Radiology February 2009 – PRESENT W. Edward Chamberlain Professor of

Diagnostic Imaging Temple University School of

Medicine

Page 4: CURRICULUM VITAE June 30, 2013 BIOGRAPHICALCURRICULUM VITAE June 30, 2013 BIOGRAPHICAL NAME: Charles A. Jungreis, M.D. ADDRESS: Office TUH Department of Radiology 3401 North Broad

4CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

CERTIFICATION AND LICENSURE SPECIALTY CERTIFICATION: JUNE 1984 American Board of Radiology JULY 1986 American Society of Neuroradiology (Senior Member) NOVEMBER 1995 American Board of Radiology

Certificate of Added Qualifications in Neuroradiology (CAQ)

JULY 16, 2004 American Board of Radiology

Maintenance of Certification (MOC) of Added Qualifications in Neuroradiology (CAQ). Certification until 2015.

MEDICAL LICENSURE: DECEMBER 1981 - PRESENT New York State JUNE 1986 - PRESENT Pennsylvania MEMBERSHIPS IN PROFESSIONAL AND SCIENTIFIC SOCIETIES 1986 - 2003 Pittsburgh Neuroradiology Society 1983 - PRESENT The Radiological Society of North America (RSNA) 1984 - PRESENT American College of Radiology (ACR) 1985 - PRESENT The American Society of Neuroradiology (ASNR) 1986 - PRESENT Association of University

Page 5: CURRICULUM VITAE June 30, 2013 BIOGRAPHICALCURRICULUM VITAE June 30, 2013 BIOGRAPHICAL NAME: Charles A. Jungreis, M.D. ADDRESS: Office TUH Department of Radiology 3401 North Broad

5CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Radiologists (AUR) - Emeritus 9-16-2004 1987 - PRESENT American Medical Association (AMA) 1989 - PRESENT North American Skull Base Society (Founding Member) 1989 - PRESENT Pennsylvania Medical Society 1989 - 2003 Allegheny County Medical Society 1990 - PRESENT World Federation of Interventional Therapeutic Neuroradiology (WFITN) (Founding Member) 1990 - 2003 University of Pittsburgh Cerebral Blood Flow and Metabolism Society 1992 - PRESENT Society of Cardiovascular and Interventional Radiology (SCVIR) 1992 - 2003 International Stereotactic Radiosurgery Society (ISRS) (Charter Member) 1993 - PRESENT Joint Section on Cerebrovascular Surgery of The American Association of Neurological Surgeons (AANS) and The Congress of Neurological Surgeons (CNS) 1999 - PRESENT American Society of Interventional and Therapeutic Neuroradiology (ASITN) PUBLICATIONS (* = fellow, resident, or medical student supervised on project) REFEREED ARTICLES: 1. Jungreis CA, McKinley M. Ectopic Gastric Mucosa - Rare but not Forgotten. Gastrointestinal Endoscopy 1984;30:48-49. Reprinted in GI Endoscopy 1984;30:319-320.

Page 6: CURRICULUM VITAE June 30, 2013 BIOGRAPHICALCURRICULUM VITAE June 30, 2013 BIOGRAPHICAL NAME: Charles A. Jungreis, M.D. ADDRESS: Office TUH Department of Radiology 3401 North Broad

6CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

2. Jungreis CA, Naidich J. An Unusual Cause of Subclavian Steal Syndrome. N.Y. State Journal of Medicine 1984;4:517-518. 3. Jungreis CA, Berenstein A, Choi I. Use of an Open Ended Guidewire: Steerable Microguidewire Assembly System in Surgical Neuroangiographic Procedures. AJNR 1987;8:237-241. 4. Jungreis CA, Cohen W. Spinal Cord Compression Induced by Steroid Therapy: CT Findings. JCAT 1987;11(2):245-247. 5. Jungreis CA, Chandra R, Kricheff I, Chuba JV. In Vitro Magnetic Resonance Properties of C.N.S. Neoplasms and Associated Cysts. Investigative Radiology 1988;23(1):12-16. 6. Jungreis CA, Kanal E, Hirsch WL, Martinez AJ, Moossy J. Normal Perivascular Spaces Mimicking Lacunar Infarction: MR Imaging. Radiology 1988;169:101-104. 7. Jungreis CA, Sekhar LN, Martinez AJ, Hirsch BE. Cardiac Myxoma Metastatic to the Temporal Bone. Radiology 1989;170:244. 8. *Rupp GM, Heyman RA, Martinez AJ, Sekhar LN, Jungreis CA. The Pathology of Metastatic Cardiac Myxoma. AJCP 1989;91:221-227. 9. *Erba M, Jungreis CA, Horton JA. Nitropaste for Prevention and Relief of Vascular Spasm. AJNR 1989;10:155-156. 10. Jungreis CA, Horton JA, Hecht ST. Blood Pressure Changes in Feeders to Cerebral Arteriovenous Malformations during Therapeutic Embolization. AJNR 1989;10:575-577. 11. Jungreis CA, Horton JA. Pressure Changes in the Arterial Feeder to a Cerebral AVM used as a Guide to Monitoring Therapeutic Embolization. AJNR 1989;10:1057-1060. 12. Jungreis CA, Wechsler LR, Horton JA. Intracranial Thrombolysis Via a Catheter Embedded in a Clot. Stroke 1989;20:1578-80. 13. *Tarr RW, Johnson DW, Rutigliano M, Hecht ST, Pentheny SL, Jungreis CA, Horton JA, Yonas H. Use of Acetazolamide-Challenge Xenon CT in the Asssessment of Cerebral Blood Flow Dynamics in Patients with Arteriovenous Malformation. AJNR 1990;11:441-448. 14. *Sadler L, Tarr RW, Jungreis CA, Sekhar L. Sinus Pericranii: CT and MR Findings. JCAT 1990;14:124-127. 15. Steed DL, Webster MW, DeVries EJ, Jungreis CA, Horton JA,

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7CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Sekhar L, Yonas H. Clinical Observations of the Effect of Carotid Artery Occlusion on Cerebral Blood Flow Mapped by Xenon Computed Tomography and its Correlation with Carotid Artery Back Pressure. J Vasc Surg 1990;11:38-44. 16. *Altschuler EM, Jungreis CA, Sekhar LN, Jannetta PJ, Sheptak PE. Operative Treatment of Intracranial Epidermoid Cysts and Cholesterol Granulomas: Report of 21 Cases. Neurosurgery 1990;26:606-613. 17. *Tabatabai A, Jungreis CA, Yonas H. Cervical Schwannoma Masquerading as a Glioma: MR Findings. JCAT 1990;14(3):489-490. 18. *Sadler L, Jungreis CA, Lunsford DL, Trapanotto M. Angiographic Technique to Precede Gamma Knife Radiosurgery for Intracranial Arteriovenous Malformations. AJNR 1990;11:1157-1161. 19. *Dawson RC, Tarr RW, Hecht ST, Jungreis CA, Lunsford LD, Coffey R, Horton JA. Treatment of Arteriovenous Malformations of the Brain with Combined Embolization and Stereotactic Radiosurgery: Results After 1 and 2 Years. AJNR 1990;11:857-864. 20. Zajko AB, Chablani V, Bron KM, Jungreis CA. Hemobilia Complicating Transhepatic Catheter Drainage in Liver Transplant Recipients: Management with Selective Embolization. Cardiovasc Intervent Radiol 1990;13:285-288. 21. Jungreis CA, Kerber CW. A Solution that Simulates Whole Blood in a Model of the Cerebral Circulation. AJNR 1991;12(2):329-330. 22. Horton JA, Jungreis CA, Stratemeier PH. Sharp Vascular Calcifications and Acute Balloon Rupture During Embolization. AJNR 1991;12(6):1070-1073. 23. *Tarr RW, Johnson DW, Horton JA, Yonas H, Pentheny SL, Durham S, Jungreis CA, Hecht ST. Impaired cerebral vasoreactivity after embolization of arteriovenous malformations: assessment with serial acetazolamide challenge Xenon CT. AJNR 1991;12(3):417-423. 24. Lunsford LD, Kondziolka D, Flickinger JC, Bissonette DJ, Jungreis CA, Maitz AH, Horton JA, Coffey RJ. Stereotactic radiosurgery for arteriovenous malformations of the brain. J Neurosurg 1991;75:512-524. 25. Jungreis CA. Skull-base tumors: Ethanol embolization of the cavernous carotid artery. Radiology 1991;181:741-743.

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8CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

26. Jungreis CA. Strategies for embolization of the internal carotid artery for cavernous sinus tumors. Skull Base Surgery 1991;1(4):191-199. 27. *Tarr RW, Jungreis CA, Horton JA, Pentheny S, Sekhar LN, Sen C, Janecka IP, Yonas H. Complications of preoperative balloon test occlusion of the internal carotid arteries: experience in 300 cases. Skull Base Surgery 1991;1(4):240-244. 28. Jungreis CA. Pulsatile Tinnitus from a Dural Arteriovenous Fistula. Ann Otol Rhinol Laryngol 1991; 100:951-953. 29. Levy WJ, Amassian VE, Schmid UD, Jungreis CA. Mapping of Motor Cortex Gyral Sites Non-invasively by Transcranial Magnetic Stimulation in Normal Subjects and Patients. Electroencephalogr Clin Neurophysiol Suppl 1991; 43:51-75. 30. Jungreis CA, Lunsford LD, Barker D. Angiographic Complications during Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations. AJNR 1992;13:946-948. 31. *Koslow SA, Claassen D, Hirsch WL, Jungreis CA. Gliomatosis cerebri: a case report with autopsy correlation. Neuroradiology 1992;34:331-3. 32. Bailes JE, Deeb ZL, Wilson JA, Jungreis CA, Horton JA. Intraoperative angiography and temporary balloon occlusion of the basilar artery as an adjunct to surgical clipping: technical note. Neurosurgery 1992;30:949-953. 33. *Barker DW, Jungreis CA, Horton JA, Pentheny S, Lemley T. Balloon Test Occlusion of the Internal Carotid Artery: change in stump pressure over 15 minutes and its correlation with xenon CT cerebral blood flow. AJNR 1993;14:587-590. This article reprinted in the Year Book of Vascular Surgery, Mosby-Year Book, Inc., Chicago, 1995. 34. Jungreis CA, Jannetta PJ, Yonas H. Timing treatment of a giant intracranial aneurysm by the use of magnetic resonance imaging for the determination of intraluminal clot stability. Skull Base Surgery 1993;3(1):32-36. 35. *Cusimano MD, Ohori P, Martinez AJ, Jungreis CA, Wright DC. Pituitary carcinoma. Skull Base Surgery 1994;4(1):46-51. 36. *Wildenhain SL, Jungreis CA, Barr J, Mathis J, Wechsler L, Horton JA. CT after intracranial intraarterial thrombolysis for acute strokes. AJNR 1994;15:487-492. This article reprinted in

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9CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

the Year Book of Radiology, Mosby-Year Book, Inc., Chicago, 1995. 37. *Orons PD, Zajko AB, Jungreis CA. Arterioportal fistula causing portal hypertension and variceal bleeding: treatment with a detachable balloon. JVIR 1994;5:373-376. 38. *Linskey ME, Jungreis CA, Yonas H, Hirsch WL, Sekhar LN, Horton JA, Janosky JE. Stroke risk after abrupt internal carotid artery sacrifice: accuracy of preoperative assessment with balloon test occlusion and stable Xenon-enhanced CT. AJNR 1994;15:829-843. 39. *Witt JP, Yonas H, Jungreis CA. Cerebral blood flow response pattern during balloon test occlusion of the internal carotid artery. AJNR 1994;15:847-857. 40. *Horowitz MB, Yonas H, Jungreis CA, Hung TK. Management of a giant middle cerebral artery fusiform serpentine aneurysm with distal clip application and retrograde thrombosis: case report and review of the literature. Surgical Neurology 1994;41:221-5. 41. *Horowitz MB, Jungreis CA, Quisling RG, Pollack I. Vein of Galen Aneurysms: a review and current perspective. AJNR 1994;15:1486-1496. 42. Bryan RN, Manolio TA, Schertz LD, Jungreis CA, Poirier V, Elster A, Kronmal R. A method for using MR to evaluate the effects of cardiovascular disease on the brain in the elderly: the cardiovascular health study. AJNR 1994;15:1625-1633. 43. *Barr JD, Mathis JM, Wildenhain SL, Wechsler L, Jungreis CA, Horton, JA. Acute stroke intervention with intra-arterial urokinase infusion. JVIR 1994;5:705-713. 44. *Mathis JM, Barr JD, Jungreis CA, Horton JA. Physical characteristics of balloon catheter systems used in temporary cerebral artery occlusion. AJNR 1994;15:1831-1836. 45. *Mathis JA, Barr JD, Horton JA, Jungreis CA, Lunsford LD, Kondziolka DS, Vincent D, Pentheny SP. The efficacy of particulate embolization combined with stereotactic radiosurgery for treatment of large arteriovenous malformations of the brain. AJNR 1995;16:299-306. 46. *Mathis JM, Barr JD, Jungreis CA, Yonas H, Sekhar LN, Vincent D, Pentheny SL, Horton JA. Temporary Balloon Test Occlusion of the Internal Carotid Artery: experience in 500 cases. AJNR 1995;16:749-754.

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10CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

47. Talagala SL, Jungreis CA, Kanal E, Meyers SP, Foo TKF, Rubin RA, Applegate GR. Fast 3D time-of-flight MR angiography of the intracranial vasculature. Journal of Magnetic Resonance Imaging 1995;5(3):317-323. 48. Lopez OL, Becker JT, Jungreis CA, Rezek D, Estol C, Boller F, DeKosky ST. Computed Tomography - but not Magnetic Resonance Imaging - identified periventricular white-matter lesions predict cerebrovascular disease in probable Alzheimer's disease. Archives of Neurology 1995;52:659-664. 49. Weissman JL, Jungreis CA, Johnson JT. Therapeutic embolization for control of epistaxis in a patient with hereditary hemorrhagic telangiectasia. American Journal of Otolaryngology 1995;16:138-140. 50. *Spearman MP, Jungreis CA, Wechsler LR. Angioplasty of the occluded internal carotid artery. AJNR 1995;16:1791-1796. 51. Lopez OL, Brenner RP, Becker JT, Jungreis CA, Rezek D, DeKosky ST. Electroencephalographic correlates of periventricular white matter lesions in probable Alzheimer's disease. Dementia 1995;6:343-347. 52. Jungreis CA. Commentary: The Use of Stents in Endovascular Intervention. AJNR 1995;16:1974-1976. 53. Longstreth WT, Manolio TA, Arnold A, Burke GL, Bryan RN, Jungreis CA, Enright PL, O'Leary D, Fried L. Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people: the cardiovascular health study. CHS manuscript #93. Stroke 1996;27:1274-1282. 54. Yue NC, Arnold AM, Longstreth WT, Elster AD, Jungreis CA, O'Leary DH, Poirier VC, Bryan RN. Sulcal, ventricular, and white matter changes at MR imaging in the aging brain: data from the cardiovascular health study (CHS). Radiology 1997;202(1):33-40. 55. Yue NC, Longstreth WT, Elster AD, Jungreis CA, O'Leary DH, Poirier VC. Clinically serious abnormalities found incidentally at MR imaging of the brain: data from the cardiovascular health study (CHS). CHS manuscript #81. Radiology 1997;202(1):41-46. 56. Bryan RN, Wells SW, Miller TJ, Elster AD, Jungreis CA, Poirier VC, Lind BK, Manolio TA. Infarctlike lesions in the brain: prevalence and anatomic characteristics at MR imaging of the elderly - data from the cardiovascular health study (CHS). CHS manuscript #79. Radiology 1997;202(1):47-54.

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11CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

57. Spearman MP, Jungreis CA, Wehner JJ, Gerszten PC, Welch WC. Endovascular thrombolysis in deep cerebral venous thrombosis. AJNR 1997;18:502-506. 58. *Firlik AD, Kaufmann AM, Jungreis CA, Yonas H, Wehner JJ, Spearman MP, Pentheny SL. Effect of transluminal angioplasty on cerebral blood flow in the management of symptomatic vasospasm following aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery 1997;86:830-839. 59. Lopez OL, Becker JT, Reynolds CF, Jungreis CA, Weinman S, DeKosky ST. Psychiatric correlates of MR periventricular white matter lesions in probable Alzheimer's disease. The Journal of Neuropsychiatry and Clinical Neurosciences 1997;9:246-250. 60. *Gerszten PC, Welch WC, Spearman MP, Jungreis CA, Redner R. Isolated deep cerebral venous thrombosis treated by direct endovascular thrombolysis. Surgical Neurology 1997;48:261-266. 61. Baron BC, Jungreis CA, Schaitkin B, Snyderman CH. Epistaxis: case history. Operative techniques in otolaryngology-head and neck surgery 1997;8:98-103. 62. *Swarnkar A, Jungreis CA, Peel RL. Central odontogenic fibroma and intracranial aneurysm associated with tuberous sclerosis. American Journal of Otolaryngology 1998;19(1):66-69. 63. Longstreth WT Jr., Bernick C, Manolio TA, Bryan RN, Jungreis CA, Price TR. Lacunar infarcts defined by magnetic resonance imaging of 3660 elderly people: the Cardiovascular Health Study. (Manuscript #107.) Archives of Neurology 1998;55(9):1217-25. 64 *Firlik AD. Yonas H. Kaufmann AM. Wechsler LR. Jungreis CA. Fukui MB, Williams RL. Relationship between cerebral blood flow and the development of swelling and life-threatening herniation in acute ischemic stroke. Journal of Neurosurgery 1998;89(2):243-9. 65. *Wahlig JB, Welch WC, Kang JD, Jungreis CA. Cervical intrathecal catheter placement for cerebrospinal fluid drainage: technical case report. Neurosurgery 1999;44(2):419-421. 66. *Witham TF, Nemoto EM, Jungreis CA, Kaufmann AM. Near-infrared spectroscopy monitored cerebral venous thrombolysis. Can J Neurol Sci 1999;26:48-52. 67. *Firlik KS, Kaufmann AM, Firlik AD, Jungreis CA, Yonas H. Intraarterial papaverine for the treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Surg Neurol

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12CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

1999;51:66-74. 68. *Swarnkar A, Jungreis CA, Wechsler LR, Wehner JJ. Combined intravenous and intraarterial thrombolytic therapy for treatment of an acute ischemic stroke. Journal of Stroke and Cerebrovascular Diseases 1999;8(4):264-267. 69. *Scarrow AM, Williams RL, Jungreis CA, Yonas H, Scarrow MR. Removal of a thrombus from the sigmoid and transverse sinuses with a rheolytic thrombectomy catheter. AJNR 1999;20(8):1467-1469. 70. *Levy EI, Firlik AD, Wisniewski S, Rubin G, Jungreis CA, Wechsler LR, Yonas H. Factors affecting survival rates in acute vertebrobasilar artery occlusions treated with intra-arterial thrombolytic therapy: a meta-analytical approach. Neurosurgery 1999;45(3):539-545. 71. Kaufmann AM, Firlik AD, Fukui MB, Wechsler LR, Jungreis CA, Yonas H. Ischemic core and penumbra in human stroke. Stroke 1999;30(1):93-99. 72. Wechsler LR, Jungreis CA, Massaro LM, Yonas H, Barch CA, Kassam A, Aston C, Johnson DW. Long-term follow-up of patients treated with intra-arterial urokinase for acute stroke. Journal of Stroke and Cerebrovascular Diseases 2000;9(5):213-217. 73. Longstreth WT, Arnold AM, Manolio TA, Burke GL, Bryan N, Jungreis CA, O'Leary D, Enright PL, Fried L. Clinical correlates of ventricular and sulcal size on cranial magnetic resonance imaging of 3301 elderly people: the cardiovascular health study (manuscript #127). Neuroepidemiology 2000;19(1):30-42. 74. Rubin G, Levy EI, Scarrow AM, Firlik AD, Karakus A, Wechsler LR, Jungreis CA, Yonas H. Remote effects of acute ischemic stroke: a xenon CT cerebral blood flow study. Cerebrovascular Diseases 2000;10(3):221-228. 75. Carrau RL, Snyderman CH, Kassam AB, Jungreis CA. Endoscopic and endoscopic-assisted surgery for juvenile angiofibroma. The Laryngoscope April 2001;111(3):483-487. 76. *Levy EI, Horowitz MB, Koebbe CJ, Jungreis CA, Pride GL, Dutton K, Purdy PD. Transluminal stent-assisted angioplasty of the intracranial vertebrobasilar system for medically refractory, posterior circulation ischemia: early results. Neurosurgery June 2001;48(6):1215-1223. 77. *Levy EI, Horowitz MB, Jungreis CA, Cahill AM. Lingual

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13CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

artery embolization for severe uncontrollable postoperative tonsillar bleeding: case report. Ear, Nose and Throat 2001;80:208-211. 78. Longstreth WT, Diehr P, Manolio TA, Beauchamp NJ, Jungreis CA, Lefkowitz D; for the Cardiovascular Health Study Collaborative Research Group. Cluster analysis and patterns of findings on cranial magnetic resonance imaging of the elderly: the Cardiovascular Health Study. Archives of Neurology April 2001;58(4):635-640. {manuscript #128} 79. Horowitz MB, Kassam A, Nemoto E, Arimoto J, Jungreis CA. An endovascular primate model for the production of a middle cerebral artery ischemic infarction. Interventional Neuroradiology 2001;7(3):223-227. 80. Horowitz MB, Levy EI, Koebbe CJ, Jungreis CA. Transluminal stent-assisted coil embolization of a vertebral confluence aneurysm: technique report. Surgical Neurology 2001;55:291-296. 81. *Levy E, Koebbe CJ, Horowitz MB, Jungreis CA, Pride GL, Dutton K, Kassam A, Purdy PD. Rupture of intracranial aneurysms during endovascular coiling: management and outcomes. Neurosurgery 2001;49(4):807-813. 82. Horowitz MB, Spiro R, Purdy P, Jungreis CA, Levy E, Kassam A. Meningioma embolization. Contemporary Neurosurgery 2001;23(20):1-8. 83. *Levy EI, Horowitz MB, Koebbe CJ, Jungreis CA, Pride GL, Dutton CC, Purdy PD. Transluminal stent-assisted angioplasty of the intracranial vertebrobasilar system for medically refractory, posterior circulation ischemia: early results. Neurosurgery 2001;48(6):1215-1221. 84. Kilpatrick MM, Yonas H, Goldstein S, Kassam AB, Gebel JM, Wechsler LR, Jungreis CA, Fukui MB. CT-based assessment of acute stroke: CT, CT Angiography, and Xenon-enhanced CT cerebral blood flow. Stroke 2001;32(11):2543-2549. 85. Horowitz MB, Albright AL, Jungreis CA, Levy EI, Stevenson K. Endovascular management of a basilar artery false aneurysm secondary to endoscopic third ventriculostomy: case report. Neurosurgery 2001;49(6):1461-1465. 86. Maitz AH, Niranjan A, Jungreis CA, Kondziolka DS, Flickinger JC, Lunsford LD. Tube angulation improves angiographic targeting of arteriovenous malformations during stereotactic radiosurgery. Computer Aided Surgery 2001;6(4):225-229.

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87. *Koebbe CJ, Horowitz MB, Levy EI, Adelson D, Jungreis CA. Endovascular particulate and alcohol embolization for near-fatal epistaxis from a skull base vascular malformation. Pediatric Neurosurgery 2001;35(5):257-261. 88. *Levy EI, Horowitz MB, Koebbe C, Jungreis CA. Target-specific multimodality endovascular management of carotid artery blow-out syndrome. ENT-Ear, Nose & Throat Journal February 2002;81(2):115-118. 89. Horowitz MB, Whisnant RE, Jungreis CA, Snyderman C, Levy EI, Kassam A. Temporary balloon occlusion and ethanol injection for preoperative embolization of carotid body tumor. Ear, Nose, and Throat Journal August 2002;81(8):536-547. 90. Horowitz MB, Jungreis CA, Genevro J. Delayed rupture of a previously coiled unruptured anterior communicating artery aneurysm: case report. Neurosurgery 2002;51(3):804-806. 91. *Koebbe CJ, Horowitz MB, Levy EI, Dutton K, Jungreis CA, Purdy PD. Intraarterial thrombolysis for thromboemboli associated with endovascular aneurysm coiling: report of five cases. Interventional Neuroradiology 2002;8:151-158. 92. *Field M, Branstetter BF, Levy E, Yonas H, Jungreis CA. Dural arteriovenous fistula after ventriculostomy. Journal of Neurosurgery 2002;97:227. 93. Mendez OE, Shang J, Jungreis CA, Kaufer DI. Diffusion-weighted MRI in Creutzfeldt-Jakob Disease: a better diagnostic marker than CSF protein 14-3-3?. Journal of Neuroimaging 2003;13:147-151. 94. *Koebbe CJ, Horowitz MB, Jungreis CA, Levy E, Pless M. Alcohol embolization of carotid-cavernous indirect fistulae. Neurosurgery 2003;52(5):1111-1115. 95. *Field M, Jungreis CA, Chengelis N, Kromer H, Kirby L, Yonas H. Symptomatic cavernous sinus aneurysms: management and outcome after carotid occlusion and selective revascularization. AJNR 2003;24:1200-1207. 96. *Koebbe C, Levy EI, Horowitz MB, Jungreis CA, Kassam A, Purdy PD, Pride GL, Dutton K. Endovascular coiling of anterior communicating artery aneurysms: a review of clinical and angiographic outcomes. Contemporary Neurosurgery July 2003;25:1-6.

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97. Jungreis CA, Nemoto E, Boada F, Horowitz MB. Model of Reversible Cerebral Ischemia in a Monkey Model. AJNR October 2003;24:1834-1836. 98. Horowitz MB, Crammond D, Balzer J, Jungreis CA, Kassam AB. Aneurysm rupture during endovascular coiling: effects on cerebral transit time and neurophysiologic monitoring and the benefits of early ventriculostomy. Minimally Invasive Neurosurgery October 2003;46(5):300-305. 99. Park HK. Horowitz M. Jungreis C. Kassam A. Koebbe C. Genevro J. Dutton K. Purdy P. Endovascular treatment of paraclinoid aneurysms: experience with 73 patients. [Journal Article] Neurosurgery. 53(1):14-23; discussion 24, 2003 Jul. 100. The IMS Study Investigators (corresponding author: Joseph P. Broderick, MD). Combined intravenous and intraarterial recanalization for acute ischemic stroke: The Interventional Management of Stroke (IMS) Study. Stroke 2004;35:904-912. 101. Berlis A. Lutsep H. Barnwell S. Norbash A. Wechsler L. Jungreis CA. Woolfenden A. Redekop G. Hartmann M. Schumacher M. Mechanical thrombolysis in acute ischemic stroke with endovascular photoacoustic recanalization. [Clinical Trial. Journal Article. Multicenter Study] Stroke. 35(5):1112-6, 2004 May. 102. Nemoto EM, Jungreis CA, Larnard D, Kuwabara H, Horowitz M, Kassam A: Hyperthermia and hypermetabolism in focal cerebral ischemia. Adv. Exp. Med, 566: 83-90, 2005. 103. Longstreth WT Jr. Arnold AM. Beauchamp NJ Jr. Manolio TA. Lefkowitz D. Jungreis C. Hirsch CH. O'Leary DH. Furberg CD. Incidence, manifestations, and predictors of worsening white matter on serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study. [Journal Article] Stroke. 36(1):56-61, 2005 Jan. The Cardiovascular Health Study. Draft L26. 104. Park HK. Horowitz M. Jungreis C. Genevro J. Koebbe C. Levy E. Kassam A. Periprocedural morbidity and mortality associated with endovascular treatment of intracranial aneurysms. [Journal Article] Ajnr: American Journal of Neuroradiology. 26(3):506-14, 2005 Mar. 105. Jovin TG, Gupta R, Uchino K, Jungreis CA, Wechsler LR, Hammer MD, Tayal A, Horowitz MB. Emergent Stenting of Extracranial Internal Carotid Artery Occlusion in Acute Stroke has a High Revascularization Rate. Stroke 2005;36:2426-2430.

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106. Boada FE, Laverde G, Jungreis C, Nemoto E, Tanase C, Hancu I. Loss of cell ion homeostasis and cell viability in the brain: what sodium MRI can tell us. Curr Top Dev Biol. 2005;70:77-101. 107. Nemoto EM, Jungreis C, Jovin T, Rao G, Robinson T, Sanders T, Casey K, Kirkman J. Safety of direct local cooling (15 degrees C) of the cerebral cortex with the Chillerstrip during focal cerebral ischemia in monkeys. Adv Exp Med Biol. 2006;578:317-22. 108. LaVerde G, Nemoto E, Jungreis CA, Tanase C, Boada FE. Serial triple quantum sodium MRI during non-human primate focal brain ischemia. Magn Reson Med. 2007 Jan;57(1):201-5. 109. Jovin TG, Gupta R, Horowitz MB, Grahovac SZ, Jungreis CA, Wechsler L, Gebel JM, Yonas H. Pretreatment ipsilateral regional cortical blood flow influences vessel recanalization in intra-arterial thrombolysis for MCA occlusion. AJNR Am J Neuroradiol. 2007(Jan);28(1):164-7. 110. LaVerde GC, Jungreis CA, Nemoto E, Boada FE. Sodium time course using 23Na MRI in reversible focal brain ischemia in the monkey. J Magn Reson Imaging 2009 (July);30(1):219-223. 111. Alexander Kharlamov1, George C. LaVerde3,4, Edwin M. Nemoto3, Charles A. Jungreis5, Victor E. Yushmanov1, Stephen C. Jones1,2,3, Fernando E. Boada3,4. MAP2 Immunostaining in Thick Sections for Early Ischemic Stroke Infarct Volume in Non-Human Primate Brain. Journal of Neuroscience Methods 2009;182(2):205-210. September 15, 2009. BOOKS and CHAPTERS: 1. Jungreis CA: Contributor to A Handbook of Nuclear Medicine by J. Walker and D. Margouleff. Appelton-Century-Crofts, Norwalk, CT, 1984. 2. Jungreis CA, Chandra R, Kricheff II, Chuba JV. In Vitro Magnetic Resonance Properties of CNS Neoplasms and Associated Cysts. Reprinted in Yearbook of Diagnostic Radiology. Ann Osborn (editor). Yearbook Medical Publishers, Chicago, 1989. 3. Jungreis CA, Grossman RI. Intracranial Infections and Inflammatory Diseases. In: MR and CT Imaging of the Head, Neck and Spine (2nd edition). Latchaw RE (editor), Mosby Year Book,

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St. Louis, 1991, pp 303-346. 4. Jungreis CA, Rothfus WE, Latchaw RE. Tumors and infections of the Spine and Spinal Cord. In: MR and CT Imaging of the Head, Neck and Spine (2nd edition). Latchaw RE (editor), Mosby Year Book, St. Louis, 1991, pp 1183-1223. 5. Jungreis CA, Horton JA. Interventional Neuroradiology: Embolization. In: Surgery of Cranial Base Tumors. Sekhar LN and Janecka IP (editors), Raven Press, Ltd., New York, 1993, pp 37-44. 6. Horton JA, Jungreis CA, Pistoia F. Balloon Test Occlusion. In: Surgery of Cranial Base Tumors. Sekhar LN and Janecka IP (editors), Raven Press, Ltd., New York, 1993, pp 33-36. 7. Jungreis CA. Vascular and Choroidal Anatomy. In: MRI Atlas of the Central Nervous System. Kanal E and Fix JD (editors). In Press. 8. Jungreis CA, Hirsch WL, Curtin HD. Radiographic evaluation of Acoustic Neuromas. In: Surgery of Acoustic Neuromas. Peter J. Jannetta (editor), Thieme Medical Publishers, Inc., New York (in press). 9. Jungreis CA. Angiography, embolization, and cerebrovascular studies of cranial base tumors. In: Problems in Plastic and Reconstructive Surgery - Principles in Cranial Base Surgery. Ivo P. Janecka (editor), JB Lippincott Company, Hagerstown, MD. Vol. 3, no. 1, April, 1993, pp 37-50. 10. Horowitz MB, Jungreis CA, Quisling RG. Vein of Galen Aneurysms. In: Cerebrovascular Disease, edited by H. Hunt Batjer. Lippincott-Raven Publishers, New York and Philadelphia, 1997. 11. Jungreis CA, Meltzer CC. Imaging Update. In: Advances in Neuro-Oncology II. Edited by Drs. Paul L. Kornblith and Michael D. Walker. Futura Publishing Co., Inc., Armonk, New York, 1997. 12. Wechsler LR, Jungreis CA. Intra-arterial Thrombolysis for carotid circulation ischemia. In: Critical Care Clinics: endovascular therapy and neurocritical care. Editor: Camilio R. Gomez, MD. October 1999;15(4):701-718. WB Saunders Company, Philadelphia. 13. Jungreis CA, Yonas H, Firlik AD, Wechsler LR. Advanced CT Imaging (Functional CT). In: Neuroimaging Clinics of North America: Acute Ischemic Stroke. Editor Gary M. Nesbit, MD. WB

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Saunders Company, Philadelphia, PA. Volume 9, number 3, August 1999, pp. 455-464. 14. Jungreis CA. Cerebrovascular intervention: Ischemic stroke and vasospasm. 2000 Categorical Course in Diagnostic Neuroradiology: Neuroradiology 2000. Annual Meeting of the Radiological Society of North America (RSNA), Chicago, November, 27, 2000. James Smirniotopoulos, MD, editor. RSNA 2000, Oak Brook, IL, November, 2000, pp 33-38. 15. Kanamalla US, Jungreis CA, Kochan JP. “Direct Carotid Cavernous Fistula”. In: Interventional Neuroradiology. Edited by Robert W. Hurst and Robert H. Rosenwasser, Informa Healthcare USA, Inc., New York, 2008, pp. 231-238. 16. Horowitz MB, Gologorsky Y, Jungreis CA, Quisling, RG, Pollack IF. Vein of Galen Malformations. Chapter 24, pp 163-170. In: Neurosurgical Operative Atlas: Vascular Neurosurgery. Editor – R. Loch MacDonald, MD, PhD. Thieme,New York. October 2008. 17. Kanamalla US, Jungreis CA. “Direct Carotid Cavernous Fistula”. In: Neurointerventional Management: diagnosis and treatment, 2nd Edition. Edited by Robert W. Hurst and Robert H. Rosenwasser, Informa Healthcare USA, Inc., New York, 2012. LETTERS: *Clyde B, Yonas H, Kaufmann AM, Jungreis CA. Vascular considerations and complications in cranial base surgery. Comment on: Neurosurgery 1994 Sep;35(3):351-62; discussion 362-3. Neurosurgery 1995;36(5):1058-60. Yonas H, Jungreis C. Xenon CT cerebral blood flow: past, present, and future. Comment on: AJNR Am J Neuroradiol 1994 May;15(5):845-6. AJNR Am J Neuroradiol 1995;16(1):219-220. Kaufmann AM, Firlik AD, Fukui MB, Wechsler LR, Jungreis CA, Yonas H. Comments: Ischemic core and penumbra in human stroke. Stroke 1999;30(5):1150-1153. Yonas H, Pindzola RR, Jungreis CA, Nemoto EM. Absence of selective deep white matter ischemia in chronic carotid disease. AJNR Am J Neuroradiol 2001;22(1):225-227. Jungreis CA, Loftus CM: Editorial comment on “Thin-section diffusion-weighted imaging of the infratentorium in patients with

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acute cerebral ischemia without apparent lesion on conventional diffusion-weighted imaging”. Neurologia Medico-Chirurgica (Tokyo) 2008;48:113. Jungreis CA, Loftus CM. Commentary on “Thin-section diffusion-weighted imaging of the infratentorium in patients with acute cerebral ischemia without apparent lesion on conventional diffusion-weighted imaging, by Sorimachi T, Ito Y, Morita K, Fujii Y. NeurolMed Chir (Tokyo) 2008;48:107-113. PUBLISHED ABSTRACTS: Jungreis CA, Berenstein A, Choi I: Use of an Open-End Guidewire-Steerable Microguide Wire Coaxial Assembly in Interventional Neuroradiology, Presented at the 24th Annual Meeting of the American Society of Neuroradiology, San Diego, California, January 18-23, 1986. Jungreis CA, Kanal E, Hirsch WL, Martinez AJ, Moossy J: MR of Perivascular Spaces Mimicking Lacunar Infarction. Presented at the Annual Meeting of the RSNA, Chicago, IL 1987. *Hecht ST, Jungreis CA: Preoperative Detachable Balloon Embolization in Temporal Bone Tumors. Presented at the Annual Meeting of the ASNR, Chicago, IL, 1988. Jungreis CA, Horton JA, Hecht ST. Blood Pressure Changes in Feeders to Cerebral Arteriovenous Malformations during Therapeutic Embolization. Stroke 1989;AB-9943-89. Jungreis CA, Horton JA, Hecht S: Hemodynamic Changes in Feeders to Cerebral Arteriovenous Malformations During Therapeutic Embolization. Presented at the 27th Annual Meeting of the American Society of Neuroradiology, Orlando, Florida, March 19-24, 1989. *Tarr RW, Johnson DW, Rutigliano M, Hecht ST, Yonas H, Pentheny S, Jungreis CA, Horton JA: Cerebral Blood Flow Dynamics in Patients with Arteriovenous Malformations Using Acetazolamide Challenge Xenon Computed Tomography. Presented at the 27th Annual Meeting of the ASNR, Orlando, Florida, March 1989. Steed DL, deVries EJ, Yonas H, Jungreis CA, Webster MW: Xe CT

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20CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Blood Flow Predicts Effect of Carotid Artery Occlusion: Correlation with Carotid Artery Stump Pressure. Annual Meeting International Society for Cardiovascular Surgery. New York, June 19-21, 1989. *Tarr RW, Johnson DW, Pentheny S, Hecht ST, Jungreis CA, Horton JA, Yonas H. Low Flow Demand Versus Low Flow Reserve in Arteriovenous Malformation Patients. Presented at the 75th Annual Meeting of the Radiological Society of North America. November 1989, Chicago IL. *Erba M, Jungreis CA, Horton JA. Nitropaste for Prevention and Relief of Vascular Spasm. Stroke 1990;AB-9807-89. *Dawson RC, Tarr RT, Jungreis CA, Hecht ST, Lunsford LD, Coffey R, Horton JA: Combined Embolization and Stereotactic Radiosurgery of Arteriovenous Malformations: One Year Follow-up. Presented at the 28th Annual Meeting of the American Society of Neuroradiology, Los Angeles, California, March 1990. *Tarr RW, Johnson DW, Yonas H, Jungreis CA, Hecht ST, Horton JA. Hemodynamic Alterations Following Arteriovenous Malformation Embolization: Assessment with Acetazolamide Challenge Xenon Computerized Tomography. The 28th Annual Meeting of the American Society of Neuroradiology, March 1990, Los Angeles, CA. *Altschuler EM, Lunsford DL, Jungreis CA, Sclabassi R, Martinez AJ. Radiological Models for Radiosurgery. Annual meeting of the American College of Surgeons, San Francisco, October 1990. *Kondziolka D, Lunsford LD, Flickinger JC, Bissonette D, Jungreis CA, Maitz AH, Horton JA, Coffey RJ. Stereotactic radiosurgery for arteriovenous malformations of the brain. Annual meeting of the American Society of Therapeutic Radiation Oncology. Miami, Florida, October 1990. Jungreis CA, Tarr RT, Pentheny SL, Horton JA. Complications of Balloon Test Occlusion of the Internal Carotid Artery: experience in 300 cases. Annual meeting of the North American Skull Base Society. Lake Buena Vista, Florida, February 27-March 3, 1991. *Rodgers G, Snyderman C, Jungreis CA, Janecka IP, Sekhar L. Importance of extracranial - intracranial collateral circulation in cranial base surgery. Annual meeting of the North American Skull Base Society. Lake Buena Vista, Florida, February 27-March 3, 1991. Levy W, Schmidt U, Vahe A, Jungreis CA. Identification of Gyral Sites Stimulated by Transcranial Magnetic Stimulators using an

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MRI System. Annual Meeting of American Association of Neurological Surgeons (AANS), New Orleans, LA - April 20-25, 1991. *Tarr RW, Jungreis CA, Pentheny S, Horton JA. Complications of Preoperative Balloon Test Occlusion of the ICA: Experience in 300 Cases. Annual Meeting of the American Society of Neuroradiology (ASNR), Washington DC, June 9-14, 1991. *Linskey MF, Jungreis CA, Yonas H, Hirsch WL, Horton JA, Sekhar LN. Clinical Balloon Test Occlusion Coupled with Stable Xenon CT Cerebral Blood Flow Analysis for Assessment of the Risk of Acute Therapeutic ICA Occlusion. Annual Meeting, American Association of Neurological Surgeons (AANS), San Francisco, CA. April 11-16, 1992. Talagala SL, Jungreis CA, Kanal E, Meyers SP, Rubin R. Fast Three Dimensional Time-of-flight MR Angiography with Contrast Bolus Injection. Annual Meeting of the Society of Magnetic Resonance Imaging (SMRI), New York, NY - April 1992. Bryan RN, Elster A, Jungreis CA, Manolio TA, Poirier V, Schertz LD. Correlation of Magnetic Resonance (MR) Imaging of Stroke and Clinical History of Stroke in the Cardiovascular Health Study. Annual Meeting of the American Society of Neuroradiology (ASNR), St. Louis, MO - June 1992. *Johnson DW, Witt P, Yonas H, Horton JA, Jungreis CA, Linskey M. Quantitative CBF Testing is Necessary in Balloon Test Occlusion. Annual Meeting of the American Society of Neuroradiology (ASNR), St. Louis, MO - June 1992. *Linskey M, Jungreis CA, Yonas H, Hirsch WL, Horton JA, Sekhar LN. Clinical Balloon Test Occlusion Coupled with Stable Xenon CT Cerebral Blood Flow Analysis for Assessment of the Risk of Acute Therapeutic ICA Occlusion. Third Annual Meeting of North American Skull Base Society, Acapulco, Mexico - February 15-20, 1992. Jungreis CA. Balloon Test Occlusion of the ICA. Third Annual Meeting of the North American Skull Base Society, Acapulco, Mexico - February 15-20, 1992. *Mathis JM, Barr JD, Horton JA, Jungreis CA, Vincent D. Complications of balloon test occlusion of cerebral arteries: experience in 475 cases. Fourth annual meeting of the North American Skull Base Society, Scottsdale, Arizona, February 12-14, 1993.

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22CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

*Barr JD, Mathis JM, Wildenhain SL, Horton JA, Jungreis CA. Acute stroke intervention with intraarterial urokinase infusion. 18th annual meeting of the Society of Cardiovascular and Interventional Radiology (SCVIR), New Orleans, Louisiana, February 28, 1993. *Mathis JM, Barr JD, Vincent D, Jungreis CA, Pentheny SL, Lunsford DL, Horton JA. The efficacy of particulate embolization and stereotactic radiosurgery for large AVMs of the brain. Annual meeting of the Association of Neurological Surgeons (AANS), Boston, April 24-28, 1993. *Mathis JM, Barr JD, Jungreis CA, Horton JA. Physical characteristics of balloon catheters used in temporary cerebrovascular occlusion. Presented at the 31st annual meeting of the American Society of Neuroradiology, Vancouver, May 14-20, 1993. *Mathis JM, Jungreis CA, Barr JD, Pentheny S, Horton JA. Comparison of Stable Xe/CT and SPECT cerebral blood flow analysis during balloon test occlusion. Presented at the 31st annual meeting of the American Society of Neuroradiology, Vancouver, May 14-20, 1993. *Mathis JM, Barr JD, Jungreis CA, Yonas H, Sekhar LN, Vincent D, Horton JA, Pentheny S. Temporary Balloon Test Occlusion of the Internal Carotid Artery: Experience in 500 cases. Presented at the 31st annual meeting of the American Society of Neuroradiology, Vancouver, May 14-20, 1993. *Fossett D, Sekhar LN, Jungreis CA, Bank W. The use of intraoperative angiography for the recognition and correction of vein graft problems during cranial base and cerebrovascular surgery. The 1994 Joint Annual Meeting of the German and North American Skull Base Societies. February 21, 1994, Lake Buena Vista, Florida. Lopez OL, Becker JT, Jungreis CA, Rezek D, Estol C, Boller F, DeKosky ST. CT - but not MR - identified periventricular white-matter lesions predict cerebrovascular disease in probable Alzheimer's disease. Journal of Neurology 1994 (Suppl. 1);241:47-48. Lopez OL, Becker JT, Jungreis CA, Brenner R, Rezek D, DeKosky ST, Estol C, Boller F. Electroencephalographic correlates of periventricular white-matter lesions in probable Alzheimer's disease. Journal of Neurology 1994 (Suppl. 1);241:14. Yonas H, Kanal E, Jungreis CA, Ferrell R. Incidence of aneurysms

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23CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

in high risk family members of patients with aneurysmal SAH. Abstract at the annual meeting of the Congress of Neurological Surgeons, Chicago, October, 1994. *Spearman MP, Jungreis CA, Wechsler LR. Traversing a complete carotid occlusion during an acute stroke for the purpose of delivering intracranial, intraarterial thrombolytic therapy. Presented at the annual meeting of the Radiological Society of North America (RSNA), Chicago, November 28, 1994. Bryan RN, Wells SW, Jungreis CA, Elster A, Poirier V, Manolio TA. Prevalance and anatomic characteristics of infarct-like lesions in the elderly: preliminary data from the cardiovascular health study (CHS). Presented at the annual meeting of the Radiological Society of North America (RSNA), Chicago, November 28, 1994. Jungreis CA, Spearman MP, Wechsler LR. Endovascular recanalization of acute carotid occlusion. Scientific paper presented at the annual meeting of the North American Skull Base Society, February 20,1995, Naples, Florida. Yue NC, Longstreth W, Elster A, Jungreis CA, O'Leary DH, Poirier V, Bryan RN. Unsuspected masses and other lesions on cranial MRI in the elderly: the Cardiovascular Health Study. Annual meeting of the ASNR, Chicago, April, 1995. Yue NC, Longstreth W, Miller T, Elster A, Jungreis CA, O'Leary DH, Poirier V, Bryan RN. MRI appearance of cerebral atrophy and white matter changes in the aging brain: the Cardiovascular Health Study. Annual meeting of the ASNR, Chicago, April, 1995. Weinman SD, Lopez OL, Becker JT, Rezek D, Jungreis CA, Dekosky T. Psychiatric correlates of periventricular white matter lesions in probable Alzheimer's disease. Presented at the annual meeting of the American Academy of Neurology (AAN), Seattle, WA, May 6-13, 1995. Neurology (reference pending). Jungreis CA. Vascular tumors of the head and neck. Guest speaker at the 4th International Conference on Head and Neck Cancer, July 28 - August 1, 1996, Toronto, Canada. Manuscript published in the Proceedings of the 4th International Conference on Head and Neck Cancer. *Gerszten PC, Welch WC, Jungreis CA, Moossy JJ, Segal R. An assessment of preoperative embolization of renal cell carcinoma metastases to the spine. Annual meeting of the American Association of Neurological Surgeons (AANS), April 27-May 2, 1996, Minneapolis, Minnesota.

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24CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Jungreis CA, Maitz AH, Lunsford LD, Kondziolka DS, Flickinger JC. Angulation limits during angiography when localizing a target volume for stereotactic radiosurgery with the Leksell gamma knife. 1996 Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), December 1-6, 1996, Chicago, IL. Yonas H, Pindzola R, Jungreis CA, Meltzer CC. Quantitative versus qualitative CBF data in the assessment of cerebrovascular reserve: clear vs. "fuzzy" logic. Poster presentation at the Annual Meeting of the Congress of Neurological Surgeons (CNS), Montreal, Canada, September 28 - October 3, 1996. Abstract printed in 46th Annual Meeting Program of the Congress of Neurological Surgeons (CNS). Firlik AD, Kaufmann AM, Jungreis CA, Yonas H. The effect of angioplasty on cerebral blood flow in the management of vasospasm following aneurysmal subarachnoid hemorrhage. Poster presentation at the Annual Meeting of the Congress of Neurological Surgeons (CNS), Montreal, Canada, September 28 - October 3, 1996. Abstract printed in 46th Annual Meeting Program of the Congress of Neurological Surgeons (CNS). Nemoto EM, Yonas H, Kaufmann AD, Jungreis CA, Klementavicius R. Cerebrovascular responses to vasopressors before and after subarachnoid hemorrhage (SAH) in monkeys assessed by Xe/CT. Acta Neurologica Scandinavica 1996;93(supplement 166):129-130. Bernick C, Longstreth WT Jr, Manolio TA, Jungreis CA, Price TR, Bryan N. Clinical factors associated with lacunes on cranial magnetic resonance imaging (MRI) of 3660 elderly people: the cardiovascular health study (CHS). manuscript #107, abstract submitted 8/96 to 22nd International Joint Conference on Stroke and Cerebral Circulation to be held February 6-8, 1997, Anaheim, CA. Bernick C, Longstreth WT Jr, Manolio TA, Jungreis CA, Price TR, Bryan N. Clinical factors associated with lacunes on cranial magnetic resonance imaging (MRI) of 3660 elderly people: the cardiovascular health study (CHS). (CHS manuscript #107). Abstract from the 22nd International Joint Conference on Stroke and Cerebral Circulation held February 6-8, 1997, Anaheim, CA, published in the January 1997 issue of Stroke. Kaufmann AM, Firlik A, Yonas H, Wechsler L, Barch C, Fukui MB, Wehner JJ, Spearman MP, Jungreis CA. Emergent stroke therapy and quantitative cerebral blood flow. American Heart Association 22nd International Joint Conference on Stroke and Cerebral Circulation. Anaheim, CA, February 6-8, 1997. Stroke

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1997;28(1):253. Kaufmann AM, Firlik AD, Yonas H, Fukui MB, Wehner JJ, Jungreis CA, Wechsler LR, Barch C. Prediction of intra-arterial thrombolysis complications with quantitative cerebral blood flow measurements. American Society of Neuroradiology Annual Meeting, May 19, 1997, Toronto, Canada. Meltzer CC, Yonas H, Pindzola RR, Jungreis CA. Qualitative versus quantitative assessment of cerebrovascular reserves. American Society of Neuroradiology Annual Meeting, May 22, 1997, Toronto, Canada. Jungreis CA. Xenon CT Cerebral Blood Flow and the Endovascular Management of Cerebrovascular Disease. Presented at the Fourth International Conference on Xenon CT CBF. Baylor College of Medicine Department of Neurology and the Salzburg Conference on Cerebrovascular Disease (Chairman - John Stirling Meyer, MD, Professor of Neurology, Baylor College of Medicine). Houston, Texas, June 11, 1997. Journal of Stroke and Cerebrovascular Disease. Wechsler LR, Jungreis CA, Massaro LM, Wehner JJ, Knepper LE, Yonas H, Kaufmann AM, Barch CA, Johnson DW. Long term followup of patients treated with intraarterial urokinase for acute stroke. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):303. Firlik AD, Rubin G, Yonas H, Wechsler LR, Jungreis CA. Selection of patients for acute stroke therapy: the role of cerebral blood flow measurements in identifying patients with transient ischemic neurological deficits. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):311. Rubin G, Firlik AD, Yonas H, Wechsler LR, Jungreis CA. Relationship between cerebral blood flow and early clinical outcome in acute ischemic stroke. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):311. Kaufmann AM, Firlik AD, Fukui MB, Wechsler LR, Jungreis CA, Yonas H. The ischemic core and penumbra in human stroke. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):312. Knepper LE, Wehner JJ, Jungreis CA, Yonas H, Wechsler LR.

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Thromboembolic stroke due to acute internal carotid artery occlusion. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):314. Wechsler LR, Jungreis CA, Massaro LM, Wehner JJ, Knepper LE, Yonas H, Kaufmann AM, Barch CA, Johnson DW. Long term followup of patients treated with intraarterial urokinase for acute stroke. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):303. Firlik AD, Rubin G, Yonas H, Wechsler LR, Jungreis CA. Selection of patients for acute stroke therapy: the role of cerebral blood flow measurements in identifying patients with transient ischemic neurological deficits. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):311. Rubin G, Firlik AD, Yonas H, Wechsler LR, Jungreis CA. Relationship between cerebral blood flow and early clinical outcome in acute ischemic stroke. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):311. Kaufmann AM, Firlik AD, Fukui MB, Wechsler LR, Jungreis CA, Yonas H. The ischemic core and penumbra in human stroke. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):312. Knepper LE, Wehner JJ, Jungreis CA, Yonas H, Wechsler LR. Thromboembolic stroke due to acute internal carotid artery occlusion. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Stroke 1998;29(1):314. Kaufmann AM, Firlik AD, Fukui MB, Wechsler LR, Jungreis CA, Yonas H. Treatment of proximal middle cerebral artery occlusions with intra-arterial urokinase. Neurosurgery September 1998;43(3):708. Kaufmann AM, Firlik AD, Fukui MB, Wechsler LR, Jungreis CA, Yonas H. Defining target tissue for acute stroke interventions. Neurosurgery September 1998;43(3):714. Kassam A, Yonas H, Pentheny S, Kirby L, Jungreis CA, Fukui MB, Kaufmann AM. Xenon-computed tomography in spontaneous intracerebral hemorrhages: physiologic guide for radical medical and surgical management. Neurosurgery September 1998;43(3):712.

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*Levy EI, Firlik AD, Rubin G, Jungreis CA, Yonas H. Is intraarterial thrombolysis for acute vertebrobasilar artery occlusion justified? A meta-analysis of prognostic factors. 1998 Congress of Neurological Surgeons Annual Meeting, Seattle, Washington, October 5, 1998. Neurosurgery September 1998;43(3):671. Jungreis CA, Wechsler LR, Massaro LM, Wehner JJ, Knepper LE, Yonas H, Barch CA, Johnson DW. Relationship between recanalization after intraarterial urokinase and clinical outcome in acute stroke. Radiological Society of North America (RSNA) Program Book, 1998 (final reference pending). Longstreth WT, Bernick C, Manolio TA, Bryan N, Jungreis CA, Price TR. Lacunar infarcts defined by magnetic resonance imaging of 3660 elderly people. Stroke 1998;29(12):2672. Jungreis CA. Xenon CT for evaluation of acute infarction. Focus session entitled Perfusion Imaging. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 25,1999. Yonas H, Jungreis CA, Fukui MB, Wechsler LR, Goldstein S, Gebel J, Kassam A. Emergent stroke evaluation: CT/CT angiography/Xenon CT. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 23-28,1999. Fukui MB, Jungreis CA, Kassam A, Gebel J, Ashton C, Karakus A, Yonas H. Xenon computed tomography as a means to predict outcome from spontaneous intracerebral hemorrhage. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 23-28,1999. Fukui MB, Kassam A, Gebel J, Jungreis CA, Pentheny SL, Yonas H. Xenon computed tomography in spontaneous intracerebral hemorrhages: a physiologic guide for rational medical and surgical management. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 23-28,1999. Jungreis CA. Xenon CT for evaluation of acute infarction. Focus session entitled Perfusion Imaging. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 25,1999. Yonas H, Jungreis CA, Fukui MB, Wechsler LR, Goldstein S, Gebel J, Kassam A. Emergent stroke evaluation: CT/CT angiography/Xenon CT. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 23-28,1999.

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Fukui MB, Jungreis CA, Kassam A, Gebel J, Ashton C, Karakus A, Yonas H. Xenon computed tomography as a means to predict outcome from spontaneous intracerebral hemorrhage. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 23-28,1999. Fukui MB, Kassam A, Gebel J, Jungreis CA, Pentheny SL, Yonas H. Xenon computed tomography in spontaneous intracerebral hemorrhages: a physiologic guide for rational medical and surgical management. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 23-28,1999. Carrau RL, Snyderman CH, Kassam A, Jungreis CA. Endoscopic and endoscopic-assisted surgery for juvenile angiofibroma. Presented at the Annual North American Skull Base Society (NASBS) Meeting, Scotsdale, Arizona, March 17-20, 2000. Skull Base Surgery March 2000;10(supplement 1):4. Jungreis CA. Xenon CT Cerebral Blood Flow in the triage for acute stroke intervention. Focus session entitled "Stroke". Invited speaker at the Year 2000 Annual Meeting of the American Society of Neuroradiology (ASNR). Atlanta, Georgia, April 4, 2000. Jungreis CA. Triage of the acute stroke patient. "Emerging Interventional Therapies: Stroke Conference" sponsored jointly by the Society of Cardiovascular and Interventional Radiology (SCVIR), the American Society of Interventional and Therapeutic Neuroradiology (ASITN), and the American Society of Neuroradiology (ASNR), Washington, DC, October 16, 2000. (Program chairman - Dr. Buddy Connors 703-698-3030.) Kilpatrick MM, Yonas H, Kassam AB, Wechsler LR, Goldstein S, Gebel J, Jungreis CA. CT based assessment of acute stroke. Presented at the annual meeting of the Congress of Neurological Surgeons (CNS), San Antonio, Texas, September 24-8, 2000. Goldstein S, Yonas H, Gebel JM, Kassam A, Jungreis CA, Uzun G, Firlik AD, Rubin G, Wechsler LR. Acute cerebral blood flow as a predictive physiologic marker for symptomatic hemorrhagic conversion and clinical herniation after thrombolytic therapy. Stroke 2000;31:275. *Field M, Yonas H, Chengelis N, Kromer H, Jungreis CA, Horowitz MB, Kassam AB. Selective extracranial-intracranial revascularization in patients undergoing internal carotid artery occlusion for symptomatic cavernous sinus aneurysms: indications and long term results in 25 patients. Joint meeting of the

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AANS/CNS Section on cerebrovascular surgery, the Japanese society of surgery for cerebral stroke, the ASITN, and the Japanese society of neuroendovascular treatment. Waikoloa Village, Hawaii, February 7-12, 2001. *Levy EI, Horowitz MB, Jungreis CA, Pride GL, Dutton K, Purdy PD. Intra-procedural rupture of intracranial aneurysms during coil embolization: management and outcome. Joint meeting of the AANS/CNS Section on cerebrovascular surgery, the Japanese society of surgery for cerebral stroke, the ASITN, and the Japanese society of neuroendovascular treatment. Waikoloa Village, Hawaii, February 10, 2001. *Levy EI, Horowitz MB, Jungreis CA, Pride GL, Dutton K, Purdy PD. Transluminal stent-assisted angioplasty of the intracranial vertebrobasilar system for medically refractory posterior circulation ischemia. Joint meeting of the AANS/CNS Section on cerebrovascular surgery, the Japanese society of surgery for cerebral stroke, the ASITN, and the Japanese society of neuroendovascular treatment. Waikoloa Village, Hawaii, February 11, 2001. Goldstein S, Jungreis CA, Yonas H, Mendelsohn A, Massaro LM, Wechsler LR. Time to treatment and cerebral blood flow as predictive measures of clinical outcome in patients treated with intra-arterial thrombolytic therapy. American Society of Neuroradiology (ASNR) Annual Meeting, Boston, Massachusetts, April 26, 2001. Yonas H, Jungreis CA, Kaufmann AM. CT angiography replacement of catheter angiography in management of patients with SAH: more information for less cost and greater safety. Congress of Neurological Surgeons 51st Annual Meeting. October 1, 2001, SanDiego, CA. Jovin T, Yonas H, Gebel J, Jungreis CA, Horowitz M, Goldstein S, Wechsler L. In thrombolysis treated MCA occlusion, the extent of ischemic core predicts the development of life-threatening hemorrhage or edema in conjunction with vessel recanalization. Neurology 2002;58:A76. *Koebbe CJ, Horowitz MB, Jungreis CA, Levy E, Pless M. Alcohol embolization of carotid-cavernous indirect fistulae: case series and literature review. Joint meeting of the AANS/CNS Section on cerebrovascular surgery, and the ASITN. Phoenix, Arizona, February 18, 2003. Jovin T, Gebel J, Yonas H, HorowitzM, Jungreis C, Grahovac S. Pretreatment ipsilateral regional cortical blood flow influences

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vessel recanalization in intra-arterial thrombolysis for MCA occlusion. Stroke 2003;34:280. Nemoto EM, Jungreis CA, Jovin T, Rao GR, Robinson T, Saunders T, Casey K, Kirkman J. Safety of Direct Local Cooling (15C) of the Cerebral Cortex with the ChillerStrip During Focal Cerebral Ischemia in Monkeys. 54th Annual Meeting of the Congress of Neurological Surgeons (CNS), San Francisco, October 16-21, 2004. Boada F, Laverde G, Jungreis C, Nemoto E, Tanase C. Triple/Single quantum filtered sodium MRI of acute brain ischemia. Conf Proc IEEE Eng Med Biol Soc. 2005;1:731-4. Cernetich J, Gentile NT, Reimer H, Kochan J, Kanamalla U, Jungreis C. Case Studies: Use of CTP/CTA in Acute Ischemic Stroke. SAEM Mid-Atlantic Regional Research Meeting; Hershey, PA; September 27, 2008.

SCIENTIFIC PRESENTATIONS AND LECTURES (* = fellow, resident, or medical student supervised on project) Jungreis CA, Berenstein A, Choi I: Use of an Open-End Guidewire-Steerable Microguide Wire Coaxial Assembly in Interventional Neuroradiology, Presented at the 24th Annual Meeting of the American Society of Neuroradiology, San Diego, California, January 18-23, 1986. Jungreis CA, Berenstein A, Choi I: Use of an Open-End Guidewire-Steerable Microguide Wire Coaxial Assembly in Interventional Neuroradiology, Presented at the 7th Meeting of the Working Group in Interventional Neuroradiology, Val D' Isere, France, January 18-24, 1987. Jungreis CA, Kanal E, Hirsch WL, Martinez AJ, Moossy J: MR of Perivascular Spaces Mimicking Lacunar Infarction. Presented at the Annual Meeting of the RSNA, Chicago, IL November, 1987. Jungreis CA: Interventional Neuroradiology in Evaluation and Treatment of Skull Base Tumors. Presented at the 8th meeting of the Working Group in Interventional Neuroradiology, Val D'Isere, France, January, 1988. *Hecht ST, Jungreis CA: Preoperative Detachable Balloon Embolization in Temporal Bone Tumors. Presented at the Annual Meeting of the ASNR, Chicago, IL, 1988.

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Jungreis CA, Horton JA, Hecht S: Hemodynamic Changes in Feeders to Cerebral Arteriovenous Malformations During Therapeutic Embolization. Presented at the 27th Annual Meeting of the American Society of Neuroradiology, Orlando, Florida, March 19-24, 1989. *Tarr RW, Johnson DW, Rutigliano M, Hecht ST, Yonas H, Pentheny S, Jungreis CA, Horton JA: Cerebral Blood Flow Dynamics in Patients with Arteriovenous Malformations Using Acetazolamide Challenge Xenon Computed Tomography. Presented at the 27th Annual Meeting of the ASNR, Orlando, Florida, March 1989. Horton JA, Hecht ST, Jungreis CA: Defining the endpoint of Embolization: Combined Embolization and Gamma Knife Surgery for Treatment of Intracranial Arteriovenous Malformations. Symposium on Radiosurgery: A Neurosurgical Approach to Intracranial Lesions. Charlottesville, VA, May 1989. *Hecht ST, Horton JA, Tarr RW, Dawson RC, Jungreis CA, Lunsford LD, Coffey RJ. Defining the endpoint of embolization: Combined Embolization and Gamma Knife Stereotactic Radiosurgery for Treatment of Intracranial Arteriovenous Malformations. Presented at the Radiosurgery: A Neurosurgical Approach to Intracranial Lesions Symposium, May 1989, Charlottesville, VA. Steed DL, deVries EJ, Yonas H, Jungreis CA, Webster MW: Xe CT Blood Flow Predicts Effect of Carotid Artery Occlusion: Correlation with Carotid Artery Stump Pressure. Annual Meeting International Society for Cardiovascular Surgery. New York, June 19-21, 1989. *Hecht ST, Horton JA, Jungreis CA, Dawson RC, Tarr RW. Definiendo un Punto Finale de Embolizacion: Combinacion de Embolizacion y Radiocirugia en el Tratamiento de Malformaciones Arteriovenoses Cerebrales. Presented at the First Congress of the Society of Spanish and Latin American Neuroradiologists. June 1989, La Coriuna, Spain. *Tarr RW, Johnson DW, Pentheny S, Hecht ST, Jungreis CA, Horton JA, Yonas H. Low Flow Demand Versus Low Flow Reserve in Arteriovenous Malformation Patients. Presented at the 75th Annual Meeting of the Radiological Society of North America. November 1989, Chicago IL. Jungreis CA, Horton JA. Intracranial Thrombolysis via a Microcatheter Embedded in a Clot. Presented at the 10th Annual Meeting of the Working Group in Interventional Neuroradiology, Val D'Isere, France, January, 1990.

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Jungreis CA, Horton JA, Hecht ST. Hemodynamic Changes in Feeders to Cerebral Arteriovenous Malformations During Therapeutic Embolizations. Presented at the 10th Annual Meeting of the Working Group in Interventional Neuroradiology, Val D'Isere, France, January 1990. *Dawson RC, Tarr RT, Jungreis CA, Hecht ST, Lunsford LD, Coffey R, Horton JA. Combined Embolization and Stereotactic Radiosurgery of AVM's: One Year Follow-up. Presented at the 10th Annual Meeting of the Working Group in Interventional Neuroradiology, Val D'Isere, France, January 1990. Horton JA, Jungreis CA, Hecht ST, Yonas H, Sekhar LN, Janecka I, Tarr R. The Balloon Occlusion Test-An Acute Physiologic Challenge to Cerebral Blood Flow Reserves. Presented at International Conference on Stable Xenon/CT CBF, Orlando, Florida, February 1990. *Tarr RW, Johnson DW, Yonas H, Jungreis CA, Hecht ST, Horton JA. Hemodynamic Alterations Following Arteriovenous Malformation Embolization: Assessment with Acetazolamide Challenge Xenon Computerized Tomography. Presented at the International Conference on Stable Xenon/CT CBF. February 1990, Orlando, FL. *Tarr RW, Johnson DW, Yonas H, Jungreis CA, Hecht ST, Horton JA. Hemodynamic Alterations Following Arteriovenous Malformation Embolization: Assessment with Acetazolamide Challenge Xenon Computerized Tomography. The 28th Annual Meeting of the American Society of Neuroradiology, March 1990, Los Angeles, CA. *Dawson RC, Tarr RT, Jungreis CA, Hecht ST, Lunsford LD, Coffey R, Horton JA: Combined Embolization and Stereotactic Radiosurgery of Arteriovenous Malformations: One Year Follow-up. Presented at the 28th Annual Meeting of the American Society of Neuroradiology, Los Angeles, California, March 1990. *Altschuler EM, Lunsford DL, Jungreis CA, Sclabassi R, Martinez AJ. Radiological Models for Radiosurgery. Radiosurgery Symposium. Harvard Medical School, Boston, June 1990. Jungreis CA. Pulmonary Emboli from Embolization of a Cerebral AVM. Presented at the Third Annual Interventional Neuroradiology Morbidity and Mortality Conference, Keystone CO, August 1990. Jungreis CA. Intracerebral Hemorrhage from Embolization of a Cerebral AVM. Presented at the Third Annual Interventional Neuroradiology Morbidity and Mortality Conference, Keystone CO, August 1990.

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Jungreis CA. Balloon Failures during Embolization of Arteriovenous Fistulae. Presented at the Third Annual Interventional Neuroradiology Morbidity and Mortality Conference, Keystone CO, August 1990. *Altschuler EM, Lunsford DL, Jungreis CA, Sclabassi R, Martinez AJ. Radiological Models for Radiosurgery. Annual meeting of the American College of Surgeons, San Francisco, October 1990. *Kondziolka D, Lunsford LD, Flickinger JC, Bissonette D, Jungreis CA, Maitz AH, Horton JA, Coffey RJ. Stereotactic radiosurgery for arteriovenous malformations of the brain. Annual meeting of the American Society of Therapeutic Radiation Oncology. Miami, Florida, October 1990. Jungreis CA, Tarr RT, Pentheny SL, Horton JA. Complications of Balloon Test Occlusion of the Internal Carotid Artery: experience in 300 cases. Annual meeting of the North American Skull Base Society. Lake Buena Vista, Florida, February 27-March 3, 1991. *Rodgers G, Snyderman C, Jungreis CA, Janecka IP, Sekhar L. Importance of extracranial - intracranial collateral circulation in cranial base surgery. Annual meeting of the North American Skull Base Society. Lake Buena Vista, Florida, February 27-March 3, 1991. Levy W, Schmidt U, Vahe A, Jungreis CA. Identification of Gyral Sites Stimulated by Transcranial Magnetic Stimulators using an MRI System. Annual Meeting of American Association of Neurological Surgeons (AANS), New Orleans, LA - April 20-25, 1991. *Tarr RW, Jungreis CA, Pentheny S, Horton JA. Complications of Preoperative Balloon Test Occlusion of the ICA: Experience in 300 Cases. Annual Meeting of the American Society of Neuroradiology (ASNR), Washington DC, June 9-14, 1991. *Linskey M, Jungreis CA, Yonas H, Hirsch WL, Horton JA, Sekhar LN. Clinical Balloon Test Occlusion Coupled with Stable Xenon CT Cerebral Blood Flow Analysis for Assessment of the Risk of Acute Therapeutic ICA Occlusion. Third Annual Meeting of North American Skull Base Society, Acapulco, Mexico - February 15-20, 1992. Jungreis CA. Balloon Test Occlusion of the ICA. Third Annual Meeting of the North American Skull Base Society, Acapulco, Mexico - February 15-20, 1992. *Linskey MF, Jungreis CA, Yonas H, Hirsch WL, Horton JA, Sekhar

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LN. Clinical Balloon Test Occlusion Coupled with Stable Xenon CT Cerebral Blood Flow Analysis for Assessment of the Risk of Acute Therapeutic ICA Occlusion. Annual Meeting, American Association of Neurological Surgeons (AANS), San Francisco, CA. April 11-16, 1992. Talagala SL, Jungreis CA, Kanal E, Meyers SP, Rubin R. Fast Three Dimensional Time-of-flight MR Angiography with Contrast Bolus Injection. Annual Meeting of the Society of Magnetic Resonance Imaging (SMRI), New York, NY. April, 1992. Bryan RN, Elster A, Jungreis CA, Manolio TA, Poirier V, Schertz LD. Correlation of Magnetic Resonance (MR) Imaging of Stroke and Clinical History of Stroke in the Cardiovascular Health Study. Annual Meeting of the American Society of Neuroradiology (ASNR), St. Louis, MO. June, 1992. Johnson DW, Witt P, Yonas H, Horton JA, Jungreis CA, Linskey M. Quantitative CBF Testing is Necessary in Balloon Test Occlusion. Annual Meeting of the American Society of Neuroradiology (ASNR), St. Louis, MO. June, 1992. Jungreis CA. Thalamic Infarct Secondary to Microcatheterization during Embolization of an AVM. Fourth Annual Neuroradiology Morbidity and Mortality Conference, Jackson Hole, WY. August 11-15, 1992. Jungreis CA. Delayed intraparenchymal hemorrhage after angioplasty for vasospasm due to subarachnoid hemorrhage. Fourth Annual Neuroradiology Morbidity and Mortality Conference, Jackson Hole, WY. August 11-15, 1992. *Mathis JM, Barr JD, Horton JA, Jungreis CA, Vincent D. Complications of balloon test occlusion of cerebral arteries: experience in 475 cases. Fourth annual meeting of the North American Skull Base Society, Scottsdale, Arizona, February 12-14, 1993. *Barr JD, Mathis JM, Wildenhain SL, Horton JA, Jungreis CA. Acute stroke intervention with intraarterial urokinase infusion. 18th annual meeting of the Society of Cardiovascular and Interventional Radiology (SCVIR), New Orleans, Louisiana, February 28, 1993. *Mathis JM, Barr JD, Vincent D, Jungreis CA, Pentheny SL, Lunsford DL, Horton JA. The efficacy of particulate embolization and stereotactic radiosurgery for large AVMs of the brain. Annual meeting of the Association of Neurological Surgeons (AANS), Boston, April 24-28, 1993.

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*Mathis JM, Barr JD, Jungreis CA, Horton JA. Physical characteristics of balloon catheters used in temporary cerebrovascular occlusion. Presented at the 31st annual meeting of the American Society of Neuroradiology, Vancouver, May 14-20, 1993. *Mathis JM, Jungreis CA, Barr JD, Pentheny S, Horton JA. Comparison of Stable Xe/CT and SPECT cerebral blood flow analysis during balloon test occlusion. Presented at the 31st annual meeting of the American Society of Neuroradiology, Vancouver, May 14-20, 1993. *Mathis JM, Barr JD, Jungreis CA, Yonas H, Sekhar LN, Vincent D, Horton JA, Pentheny S. Temporary Balloon Test Occlusion of the Internal Carotid Artery: Experience in 500 cases. Presented at the 31st annual meeting of the American Society of Neuroradiology, Vancouver, May 14-20, 1993. Jungreis CA. Recurrent carotid-cavernous fistula after embolization with both balloons and coils. 6th annual meeting of the Interventional Neuroradiology Morbidity and Mortality Conference, Jackson Hole, Wyoming. August 24-28, 1993. *Fossett D, Sekhar LN, Jungreis CA, Bank W. The use of intraoperative angiography for the recognition and correction of vein graft problems during cranial base and cerebrovascular surgery. The 1994 Joint Annual Meeting of the German and North American Skull Base Societies. February 21, 1994, Lake Buena Vista, Florida. Jungreis CA. Complications from embolization of a carotid-cavernous fistula. Interventional Neuroradiology Peer Review Conference. Jackson Hole, Wyoming, July 7, 1994. Jungreis CA. Hemorrhage into a meningioma during angiography. Interventional Neuroradiology Peer Review Conference. Jackson Hole, Wyoming, July 8, 1994. Lopez OL, Becker JT, Jungreis CA, Rezek D, Estol C, Boller F, DeKosky ST. CT - but not MR - identified periventricular white-matter lesions predict cerebrovascular disease in probable Alzheimer's disease. The Annual European Neurological Society Meeting, Barcelona, Spain, June 27, 1994. Lopez OL, Becker JT, Jungreis CA, Brenner R, Rezek D, DeKosky ST, Estol C, Boller F. Electroencephalographic correlates of periventricular white-matter lesions in probable Alzheimer's disease. The Annual European Neurological Society Meeting,

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36CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Barcelona, Spain, June 27, 1994. *Spearman MP, Jungreis CA, Wechsler LR. Traversing a complete carotid occlusion during an acute stroke for the purpose of delivering intracranial, intraarterial thrombolytic therapy. Presented at the annual meeting of the Radiological Society of North America (RSNA), Chicago, November 28, 1994. Bryan RN, Wells SW, Jungreis CA, Elster A, Poirier V, Manolio TA. Prevalance and anatomic characteristics of infarct-like lesions in the elderly: preliminary data from the cardiovascular health study (CHS). Presented at the annual meeting of the Radiological Society of North America (RSNA), Chicago, November 28, 1994. Jungreis CA, Spearman MP, Wechsler LR. Endovascular recanalization of acute carotid occlusion. Scientific paper presented at the annual meeting of the North American Skull Base Society, February 20,1995, Naples, Florida. Yue NC, Longstreth W, Elster A, Jungreis CA, O'Leary DH, Poirier V, Bryan RN. Unsuspected masses and other lesions on cranial MRI in the elderly: the Cardiovascular Health Study. Annual meeting of the ASNR, Chicago, April, 1995. Yue NC, Longstreth W, Miller T, Elster A, Jungreis CA, O'Leary DH, Poirier V, Bryan RN. MRI appearance of cerebral atrophy and white matter changes in the aging brain: the Cardiovascular Health Study. Annual meeting of the ASNR, Chicago, April, 1995. Weinman SD, Lopez OL, Becker JT, Rezek D, Jungreis CA, Dekosky T. Psychiatric correlates of periventricular white matter lesions in probable Alzheimer's disease. Presented at the annual meeting of the American Academy of Neurology (AAN), Seattle, WA, May 6-13, 1995. *Firlik KS, Kaufmann AM, Clyde BL, Jungreis CA, Yonas H. Intra-arterial papaverine for the treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. International workshop for cerebrovascular surgery, Chicago, IL, June 12, 1995. Nemoto EM, Yonas H, Kauffman A, Jungreis CA, Klementavicius R. Cerebrovascular responses to vasopressors before and after subarachnoid hemorrhage (SAH) in monkeys assessed by XE/CT. Third international conference on Xenon/CT Cerebral Blood Flow, June 25-28, 1995, Aarhus, Denmark. Jungreis CA. Increased cerebral vasospasm following superselective papavarine infusion. Interventional Neuroradiology Peer Review Conference. Jackson Hole, Wyoming,

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37CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

August 3, 1995. Spearman MP, Jungreis CA, Wehner JJ, Welch W, Gerszten P. Endovascular thrombolysis of straight sinus thrombosis. 7th Annual Meeting of the Eastern Neuroradiological Society, Ontario, Canada, October 6, 1995. Nemoto EM, Yonas H, Kaufmann A, Jungreis CA, Klementavicius R. Cerebrovascular responses to vasopressors before and after subarachnoid hemorrhage (SAH) assessed by Xe/CT in monkeys. Submitted to SNACC annual meeting, October 20, 1995, Atlanta, GA. Yonas H, Wehner JJ, Spearman MP, Jungreis CA, Rutigliano MJ. CT angiography - the new "Gold Standard" for definition of cervical carotid narrowing?. Annual meeting of the Joint Section on Cerebrovascular Surgery (American Association of Neurological Surgeons and the Congress of Neurological Surgeons), San Antonio, Texas, January 23-25, 1996. Jungreis CA, Nemoto EM, Yonas H, Melick J, Rao GR, Mintun M, Thulborn KR. Regional cerebral blood flow and metabolism in a monkey model of subarachnoid hemorrhage (SAH). 21st International Joint Conference on Stroke and Cerebral Circulation (American Heart Association). San Antonio, Texas, January 25-27, 1996. Jungreis CA. CTA and the skull base patient. Presented at the 2nd International Skull Base Congress and the 7th Annual Meeting of the North American Skull Base Society, San Diego, CA, June 30, 1996. Jungreis CA. Vascular tumors of the head and neck. Guest speaker at the 4th International Conference on Head and Neck Cancer, July 28 - August 1, 1996, Toronto, Canada. Manuscript to be published in the Proceedings of the 4th International Conference on Head and Neck Cancer. Jungreis CA. Complication of angioplasty of the cavernous ICA. 9th Interventional Neuroradiology Peer Review Conference, Jackson Hole, Wyoming, July 30-August 3, 1996. Kaufmann AM, Firlik AD, Yonas H, Jungreis CA, Wechsler, LR. Triage of acute stroke with stable xenon cerebral blood flow measurements: selection guidelines for thrombolytic therapy. The Third World Stroke Congress and Fifth European Stroke Congress, Munich, Germany, September, 1996. Jungreis CA. Endovascular techniques for augmentation of cerebral blood flow. Invited speaker at the "Vascular

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38CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

augmentation techniques for cerebral ischemia seminar" at the Annual Meeting of the Congress of Neurological Surgeons (CNS), Montreal, Canada, October 1, 1996. Abstract printed in 46th Annual Meeting Program of the Congress of Neurological Surgeons (CNS). Jungreis CA, Maitz AH, Lunsford LD, Kondziolka DS, Flickinger JC. Angulation limits during angiography when localizing a target volume for stereotactic radiosurgery with the Leksell gamma knife. Presented at the 82nd Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), December 4, 1996, Chicago, IL. Kaufmann AM, Firlik A, Yonas H, Wechsler L, Barch C, Fukui MB, Wehner JJ, Spearman MP, Jungreis CA. Emergent stroke therapy and quantitative cerebral blood flow. American Heart Association 22nd International Joint Conference on Stroke and Cerebral Circulation. Anaheim, CA, February 7, 1997. Kaufmann AM, Yonas H, Firlik AD, Wechsler LR, Jungreis CA, Barch C. Neurosurgical management of complicated stroke interventions. Annual meeting of the American Association of Neurological Surgeons (AANS). Denver, CO, April, 1997. Kaufmann AM, Firlik AD, Yonas H, Fukui MB, Wehner JJ, Jungreis CA, Wechsler LR, Barch C. Prediction of intra-arterial thrombolysis complications with quantitative cerebral blood flow measurements. American Society of Neuroradiology Annual Meeting, Toronto, Canada, May 16-22, 1997. Meltzer CC, Yonas H, Pindzola RR, Jungreis CA. Qualitative versus quantitative assessment of cerebrovascular reserves. American Society of Neuroradiology Annual Meeting, Toronto, Canada, May 22, 1997. Maitz AH, Jungreis CA, Lunsford LD, Kondziolka DS, Pollock BE, Flickinger JC. Limits on angiographic angulation in LGP 3.01 and LGP 4.01. 8th International Leksell Gamma Knife Society Meeting, Marseille, France, June 22-25, 1997. Jungreis CA. Acute thrombolysis of a vertebrobasilar embolus during subclavian artery angioplasty. 10th Annual Interventional Neuroradiology Peer Review Conference, Jackson Hole, Wyoming, August 1, 1997. Jungreis CA. Angiographic evaluation of the head and neck. Masters of Otolaryngology Meeting (Jonas Johnson, MD, Professor of Otolaryngology, University of Pittsburgh Medical Center - program director). March 11, 1998. Aspen, Colorado.

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39CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Jungreis CA. Complication of coil embolization in an acutely ruptured intracranial aneurysm. 11th Annual Interventional Neuroradiology Peer Review Conference. Jackson, Wyoming. July 7, 1998. Jungreis CA. Embolization of a carotid cavernous fistula. 11th Annual Interventional Neuroradiology Peer Review Conference. Jackson, Wyoming. July 8, 1998. Jungreis CA. Intraoperative, intracranial angioplasty and stent placement for treatment of vertebrobasilar artery stenosis. 11th Annual Interventional Neuroradiology Peer Review Conference. Jackson, Wyoming. July 9, 1998. *Levy EI, Firlik AD, Rubin G, Jungreis CA, Yonas H. Is intraarterial thrombolysis for acute vertebrobasilar artery occlusion justified? A meta-analysis of prognostic factors. 1998 Congress of Neurological Surgeons Annual Meeting, Seattle, Washington, October 5, 1998. Jungreis CA, Wechsler LR, Massaro LM, Wehner JJ, Knepper LE, Yonas H, Barch CA, Johnson DW. Relationship between recanalization after intraarterial urokinase and clinical outcome in acute stroke. Radiological Society of North America (RSNA) Annual Meeting, Chicago, December 3, 1998. Jungreis CA. Xenon CT for evaluation of acute infarction. Focus session entitled Perfusion Imaging. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 25,1999. Jungreis CA. Cerebral venous sinus rupture during thrombolysis for venous thrombosis. 1999 Interventional Neuroradiology Peer Review Course. Jackson Hole, Wyoming, July 31, 1999. Carrau RL, Snyderman CH, Kassam A, Jungreis CA. Endoscopic and endoscopic-assisted surgery for juvenile angiofibroma. Presented at the Annual North American Skull Base Society (NASBS) Meeting, Scotsdale, Arizona, March 17-20, 2000. Kilpatrick MM, Yonas H, Kassam AB, Wechsler LR, Goldstein S, Gebel J, Jungreis CA. CT based assessment of acute stroke. Presented at the annual meeting of the Congress of Neurological Surgeons (CNS), San Antonio, Texas, September 24-8, 2000. *Levy EI, Horowitz MB, Jungreis CA, Pride GL, Dutton K, Purdy PD. Intra-procedural rupture of intracranial aneurysms during coil embolization: management and outcome. Joint meeting of the

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40CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

AANS/CNS Section on cerebrovascular surgery, the Japanese society of surgery for cerebral stroke, the ASITN, and the Japanese society of neuroendovascular treatment. Waikoloa Village, Hawaii, February 10, 2001. *Levy EI, Horowitz MB, Jungreis CA, Pride GL, Dutton K, Purdy PD. Transluminal stent-assisted angioplasty of the intracranial vertebrobasilar system for medically refractory posterior circulation ischemia. Joint meeting of the AANS/CNS Section on cerebrovascular surgery, the Japanese society of surgery for cerebral stroke, the ASITN, and the Japanese society of neuroendovascular treatment. Waikoloa Village, Hawaii, February 11, 2001. *Spiro RM, Patel A, Horowitz MB, Kassam A, Pless M, Jungreis CA. Complications involving embolization of the external carotid artery prior to meningioma resection: a ten year experience and review of the literature. 12th Annual Meeting of the North American Skull Base Society, Lake Buena Vista, Florida. March 6, 2001. Goldstein S, Jungreis CA, Yonas H, Mendelsohn A, Massaro LM, Wechsler LR. Time to treatment and cerebral blood flow as predictive measures of clinical outcome in patients treated with intra-arterial thrombolytic therapy. American Society of Neuroradiology (ASNR) Annual Meeting, Boston, Massachusetts, April 26, 2001. Yonas H, Jungreis CA, Kaufmann AM. CT angiography replacement of catheter angiography in management of patients with SAH: more information for less cost and greater safety. Congress of Neurological Surgeons 51st Annual Meeting. October 1, 2001, SanDiego, CA. *Koebbe CJ, Horowitz MB, Jungreis CA, Levy E, Pless M. Alcohol embolization of carotid-cavernous indirect fistulae: case series and literature review. Joint meeting of the AANS/CNS Section on cerebrovascular surgery, and the ASITN. Phoenix, Arizona, February 18, 2003. Nemoto EM, Jungreis CA, Larnard D, Kuwabara H, Horowitz MB, Kassam A, Seacoast Technologies, Inc. (Portsmouth, NH 03801). Hyperthermia and hypermetabolism in focal cerebral ischemia. Presented at the International Society of Oxygen Transport to Tissue meeting in Rochester, NY, August 16-20, 2003. Nemoto EM, Jungreis CA, Jovin T, Rao GR, Robinson T, Saunders T, Casey K, Kirkman J. Safety of Direct Local Cooling (15C) of the Cerebral Cortex with the ChillerStrip During Focal Cerebral

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41CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Ischemia in Monkeys. 54th Annual Meeting of the Congress of Neurological Surgeons (CNS), San Francisco, October 16-21, 2004. Jungreis CA. Carotid Sacrifice as treatment of a direct CCF. 17th Annual Interventional Neuroradiology Conference. Jackson Hole, Wyoming. July 29, 2004. Jungreis CA. Acute Stroke Imaging. Cerebrovascular Complications Conference (CCC) 2010. Jackson Hole, Wyoming. July 14, 2010.

SCIENTIFIC EXHIBITS Hirsch WL, Jungreis CA, Martinez AJ, Moossy J, Latchaw RE, Wolf G. Post Mortem MR and Pathological Correlation. Scientific Exhibit at 25th Annual Meeting of ASNR, New York, NY, May 10-15, 1987. *Awarded Maxima Cum Laude Citation. Jungreis CA, Kanal E, Hirsch WL, Martinez AJ, Moossy J. MR of Perivascular Spaces Mimicking Lacunar Infarction. Scientific Exhibit at Annual Meeting of RSNA, Chicago, November 1988. *Included in the select group of exhibits that were certified to provide category I CME credit. *Altschuler EM, Lunsford DL, Jungreis CA, Sclabassi R, Martinez AJ. Radiobiological Models for Radiosurgery. Scientific Exhibit at the Annual Meeting of the American Association of Neurological Surgery. Nashville, April 1990. Jungreis CA, Curtin HD, Hirsch WL. Radiology of the Petrous Carotid Artery. The assessment and management of the petrous carotid artery in contemporary skull base surgery meeting. Sponsor - Skull base committee of the American Academy of Otolarygology and Head and Neck Surgeons. Chicago, September, 1990. Levy W, Schmidt U, Vahe A, Jungreis CA. Identification of gyral sites stimulated by transcranial magnetic stimulators using an MRI system. Annual meeting of the American Association of Neurological Surgeons. New Orleans, LA, April 20-25, 1991. *Linskey M, Jungreis CA, Yonas H, Hirsch WL, Horton JA, Sekhar LN. Clinical Balloon Test Occlusion Coupled with Stable Xenon CT Cerebral Blood Flow Analysis for Assessment of the Risk of Acute Therapeutic ICA Occlusion. Third Annual Meeting of North

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42CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

American Skull Base Society, Acapulco, Mexico - February 15-20, 1992. Bailes JE, Deeb ZL, Wilson JA, Jungreis CA, Horton JA. Intraoperative angiography and temporary balloon occlusion of the basilar artery as an adjunct to surgical clipping. Annual meeting of the Association of Neurological Surgeons (AANS), San Francisco, April 11-16,1992. Rubin RA, Talagala SL, Kauffman KK, Jungreis CA. Automatic Segmentation of Brain with Feature Space Editing. Annual Meeting of Society of Magnetic Resonance Imaging (SMRI), New York, NY - April 1992. *Mathis JM, Barr JD, Horton JA, Jungreis CA, Vincent D. Complications associated with external carotid artery embolization in 100 cases. Fourth annual meeting of the North American Skull Base Society, Scottsdale, Arizona, February 12-14, 1993. *Barr JD, Mathis JM, Horton JA, Jungreis CA. Provocative pharmacological testing during arterial embolization. Fourth annual meeting of the North American Skull Base Society, Scottsdale, Arizona, February 12-14, 1993. *Mathis JM, Barr JD, Horton JA, Jungreis CA. Physical characteristics of balloon catheters used in temporary cerebrovascular occlusion. Fourth annual meeting of the North American Skull Base Society, Scottsdale, Arizona, February 12-14, 1993. *Rosseau G, Sekhar LN, Wright DC, Jungreis CA, Snyderman CH. Emergent treatment of carotid artery rupture due to pseudoaneurysm. Fourth annual meeting of the North American Skull Base Society, Scottsdale, Arizona, February 12-14, 1993. Segal R, Jungreis CA. Transthoracic microsurgical discectomy without fusion in the treatment of multiple thoracic disc herniations. Poster program in the Congress of Neurological Surgeons 1993 Annual Meeting, Vancouver, BC, October 2-7, 1993. Segal R, Jungreis CA. Transthoracic microsurgical discectomy without fusion in the treatment of multiple thoracic disc herniations. Abstract at the Congress of Neurological Surgeons 1993 Annual Meeting, Vancouver, BC, October 2-7, 1993. *Foutrakis GN, Yonas H, Jungreis CA, Sclabassi R. Computer Modeling of Intracranial Aneurysm Formation and Treatment. Poster program in the Congress of Neurological Surgeons 1993

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43CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Annual Meeting, Vancouver, BC, October 2-7, 1993. Yonas H, Kanal E, Jungreis CA, Ferrell R. Incidence of aneurysms in high risk family members of patients with aneurysmal SAH. Poster pesentation at the annual meeting of the Congress of Neurological Surgeons, Chicago, October, 1994. Weinman SD, Lopez OL, Becker JT, Rezek D, Jungreis CA, Dekosky T. Psychiatric correlates of periventricular white matter lesions in probable Alzheimer's disease. Presented at the annual meeting of the American Academy of Neurology (AAN), Seattle, WA, May 6-13, 1995. *Gerszten PC, Welch WC, Jungreis CA, Moossy JJ, Segal R. An assessment of preoperative embolization of renal cell carcinoma metastases to the spine. Annual meeting of the American Association of Neurological Surgeons (AANS), April 27-May 5, 1996, Minneapolis, Minnesota. Yonas H, Pindzola R, Jungreis CA, Meltzer CC. Quantitative versus qualitative CBF data in the assessment of cerebrovascular reserve: clear vs. "fuzzy" logic. Poster presentation at the Annual Meeting of the Congress of Neurological Surgeons (CNS), Montreal, Canada, September 28 - October 3, 1996. Abstract printed in 46th Annual Meeting Program of the Congress of Neurological Surgeons (CNS). Firlik AD, Kaufmann AM, Jungreis CA, Yonas H. The effect of angioplasty on cerebral blood flow in the management of vasospasm following aneurysmal subarachnoid hemorrhage. Poster presentation at the Annual Meeting of the Congress of Neurological Surgeons (CNS), Montreal, Canada, September 28 - October 3, 1996. Abstract printed in 46th Annual Meeting Program of the Congress of Neurological Surgeons (CNS). Bernick C, Longstreth WT Jr, Manolio TA, Jungreis CA, Price TR, Bryan N. Clinical factors associated with lacunes on cranial magnetic resonance imaging (MRI) of 3660 elderly people: the cardiovascular health study (CHS). (CHS manuscript #107). Abstract accepted as a poster presentation at the 22nd International Joint Conference on Stroke and Cerebral Circulation held February 6-8, 1997, Anaheim, CA. *Firlik AD, Kaufmann AD, Yonas H, Wechsler LR, Barch C, Fukui MB, Wehner JJ, Spearman MP, Jungreis CA. Annual meeting of the American Association of Neurological Surgeons (AANS). Denver, CO, April, 1997. Wechsler LR, Jungreis CA, Massaro LM, Wehner JJ, Knepper LE, Yonas

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44CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

H, Kaufmann AM, Barch CA, Johnson DW. Long term followup of patients treated with intraarterial urokinase for acute stroke. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Firlik AD, Rubin G, Yonas H, Wechsler LR, Jungreis CA. Selection of patients for acute stroke therapy: the role of cerebral blood flow measurements in identifying patients with transient ischemic neurological deficits. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Rubin G, Firlik AD, Yonas H, Wechsler LR, Jungreis CA. Relationship between cerebral blood flow and early clinical outcome in acute ischemic stroke. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Kaufmann AM, Firlik AD, Fukui MB, Wechsler LR, Jungreis CA, Yonas H. The ischemic core and penumbra in human stroke. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Knepper LE, Wehner JJ, Jungreis CA, Yonas H, Wechsler LR. Thromboembolic stroke due to acute internal carotid artery occlusion. American Heart Association 23rd International Joint Conference on Stroke and Cerebral Circulation. February 5-7, 1998, Orlando, Florida. Yonas H, Jungreis CA, Fukui MB, Wechsler LR, Goldstein S, Gebel J, Kassam A. Emergent stroke evaluation: CT/CT angiography/Xenon CT. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 23-28,1999. Fukui MB, Jungreis CA, Kassam A, Gebel J, Ashton C, Karakus A, Yonas H. Xenon computed tomography as a means to predict outcome from spontaneous intracerebral hemorrhage. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 23-28,1999. Fukui MB, Kassam A, Gebel J, Jungreis CA, Pentheny SL, Yonas H. Xenon computed tomography in spontaneous intracerebral hemorrhages: a physiologic guide for rational medical and surgical management. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 23-28,1999. Carrau RL, Snyderman CH, Kassam A, Jungreis CA. Endoscopic and endoscopic-assisted surgery for juvenile angiofibroma. Presented

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45CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

at the Annual North American Skull Base Society (NASBS) Meeting, Scotsdale, Arizona, March 17-20, 2000. Jungreis CA. Asystole as a complication of carotid angioplasty. Thirteenth Annual Interventional Neuroradiology Peer Review Conference, Jackson Hole, Wyoming, July 27, 2000. Kilpatrick MM, Yonas H, Kassam AB, Wechsler LR, Goldstein S, Gebel J, Jungreis CA. CT based assessment of acute stroke. Presented at the annual meeting of the Congress of Neurological Surgeons (CNS), San Antonio, Texas, September 24-8, 2000. *Field M, Yonas H, Chengelis N, Kromer H, Jungreis CA, Horowitz MB, Kassam AB. Selective extracranial-intracranial revascularization in patients undergoing internal carotid artery occlusion for symptomatic cavernous sinus aneurysms: indications and long term results in 25 patients. Joint meeting of the AANS/CNS Section on cerebrovascular surgery, the Japanese society of surgery for cerebral stroke, the ASITN, and the Japanese society of neuroendovascular treatment. Waikoloa Village, Hawaii, February 7-12, 2001. Jungreis CA. Transient paraplegia after embolization of a spinal dural arteriovenous fistula. 2002 Annual Interventional Neuroradiology Morbidity and Mortality Conference, Jackson Hole, Wyoming, July 30-August 3, 2002. Boada et al. Poster. Reversible Ischemia Monkey Model with sodium imaging. ISMRM (International Society of Magnetic Resonance in Medicine). Japan, May 2004. Nemoto EM, Jungreis CA, Jovin T, Rao GR, Robinson T, Saunders T, Casey K, Kirkman J. Safety of Direct Local Cooling (15C) of the Cerebral Cortex with the ChillerStrip During Focal Cerebral Ischemia in Monkeys. Poster for the 54th Annual Meeting of the Congress of Neurological Surgeons (CNS), San Francisco, October 16-21, 2004.

PROFESSIONAL ACTIVITIES TEACHING: Visiting professorships:

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46CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Jungreis CA. "Interventional Neuroradiology." Neurology Grand

Rounds, Albert Einstein University College of Medicine. New York, May 8, 1991.

Jungreis CA. Visiting professor/grand rounds. Indiana

University. January 15, 1993. Jungreis CA. Visiting professor. North Shore University

Hospital, Cornell University Medical Center. March 5, 1993. Jungreis CA. Interventional Neuroradiology. Visiting Professor

for Radiology Grand Rounds. University of Chicago (Dr. Ruth Ramsey, Chief of Neuroradiology), May 9, 1995.

Jungreis CA. Stroke. Visiting Professor for Radiology Resident

Conference. University of Chicago (Dr. Ruth Ramsey, Chief of Neuroradiology), May 9, 1995.

Jungreis CA. Use of cerebral blood flow in evaluation of

cerebrovascular disease. Symposium on Cerebral Blood Flow at the University of Rochester (Dr. Yugi Numaguchi, presiding). University of Rochester, Strong Memorial Hospital, Rochester, New York, March 12, 1996.

Jungreis CA. Cerebral blood flow and interventional

neuroradiology. University of Chicago, Chicago, Illinois, June 17, 1997.

Jungreis CA. Cerebral blood flow and interventional

neuroradiology. State University of New York - Albany Medical Center, Albany, New York, September 18, 1997.

Jungreis CA. Acute stroke intervention. Central New York

Angiography Club (Ken Murphy, MD, president), Crouse Hospital, 736 Irving Avenue, Syracuse, NY 13210, February 25, 1999.

Jungreis CA. Cerebral blood flow in interventional

neuroradiology. Yale University School of Medicine. April 6, 2001.

Jungreis CA. Cerebral Blood Flow in Acute Stroke: an

interventionalists perspective. Medical University of South Carolina, Charleston, SC, May 30, 2002.

Jungreis CA. Cerebral ischemia and Interventional

Neuroradiology. Temple University, Philadelphia, PA, May 8, 2003.

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47CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Invited lectures: Jungreis CA. Faculty and Lecturer at Annual Meeting of the North

American Skull Base Society. "The Role of Interventional Neuroradiology in Skull Base Surgery." Los Angeles, CA, February 1990.

Jungreis CA. "Strategies for embolization of cavernous sinus

neoplasms." Invited speaker at Annual meeting of the North American Skull Base Society. Lake Buena Vista, Florida, February 27-March 3, 1991.

Jungreis CA. "Interventional Neuroradiology in Skull Base

Tumors." Faculty and Lecturer at the Joint Meeting of the Pennsylvania Neurosurgical Society and the Mid-Atlantic Neurosurgical Society, Philadelphia, PA. 9/20/91.

Jungreis CA. "Radiographic Diagnosis in Skull Base Disease."

Invited speaker at the 1994 Joint Annual Meeting of the German and North American Skull Base Societies. February 20, 1994, Lake Buena Vista, Florida.

Jungreis CA. "Thrombolytic and catheter interventional therapies

for stroke." Invited speaker at the meeting of the Tri-county medical society. Lower Burrell, PA., May 18, 1994.

Jungreis CA. Neuroimaging and endovascular intervention in acute

stroke. Sponsored by the University of Pittsburgh Medical Center. Latrobe, PA. November 18, 1994.

Jungreis CA. Brain attack: acute intervention in stroke.

Invited lecturer at Indiana Hospital, Indiana, PA, April 11, 1995.

Jungreis CA. Stroke update: new imaging techniques for stroke.

Teleconference sponsored by the University of Pittsburgh School of Medicine, April 19, 1995.

Jungreis CA. Interventional Neuroradiology. Keynote speaker at

the Annual Meeting of the Pennsylvania Neurosurgical Society, September 8, 1995, Philadelphia, PA.

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48CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Jungreis CA. Thrombolysis in acute stroke. Grand Rounds at St.

Margaret Memorial Hospital, Pittsburgh, PA, April 13, 1996. Jungreis CA. Thrombolysis in acute stroke. Grand Rounds at St.

Margaret Memorial Hospital, Pittsburgh, PA, September 21, 1996.

Jungreis CA. Cerebral blood flow and interventional

neuroradiology. University of California at Fresno, Fresno, California, July 19, 1997.

Jungreis CA. Stroke management. Teaching rounds and lecturer at

Connamaugh Hospital, Johnstown, PA. October 15, 1997. Jungreis CA. Stroke management. Brownsville General Hospital,

Brownsville, West Virginia. December 4, 1997. Jungreis CA. Acute stroke intervention. Central New York

Angiography Club (Ken Murphy, MD, president), Crouse Hospital, 736 Irving Avenue, Syracuse, NY 13210, February 25, 1999.

Abbott Labs connection is Patty O=brien p-315-438-2095, cell 315-430-5556.

Jungreis CA. Use of stable Xenon CT in neurological disease.

Neuroscience conference, Fairfax Hospital, Fairfax VA. November 19, 1999.

Jungreis CA. Imaging and acute stroke. UPMC Lee Regional

Medical Center. April 13, 2000. Jungreis CA. Endovascular therapy for cerebrovascular disease:

aneurysms and vascular malformations. American Society of Neuroimaging 24th Annual Meeting. Las Vegas, Nevada, January 27, 2001.

Jungreis CA. Cerebral revascularization for non-ischemic

cerebrovascular diseases. Joint meeting of the AANS/CNS Section on cerebrovascular surgery, the Japanese society of surgery for cerebral stroke, the ASITN, and the Japanese society of neuroendovascular treatment. Waikoloa Village, Hawaii, February 11, 2001.

Jungreis CA. Imaging triage for acute stroke intervention:

functional CT. Focus session on acute stroke. 39th Annual Meeting of the American Society of Neuroradiology (ASNR), Boston, MA, April 25, 2001. (Jacque Dion - program organizer 404-712-4991).

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Jungreis CA. Management of the Poor Grade Aneurysm Patient.

Special Course at the Annual Meeting of the Section on Cerebrovascular Surgery of the American Association of Neurological Surgeons (AANS) and the Congress of Neurological Surgeons (CNS). Dallas, Texas. February 5, 2002.

Jungreis CA. Interventional Neuroradiology. Johnson and

Johnson, Inc., New Brunswick, New Jersey. September 29, 2003.

Jungreis CA. Cerebral Blood Flow in Interventional Neuroradiology. The 2nd American-Japanese Neurosurgical Friendship Symposium and The 63rd Annual Meeting of the Japan Neurosurgical Society. Nagoya, Japan, October 5, 2004. Jungreis CA. Cerebral Blood Flow in Interventional Neuroradiology. Philadelphia Roentgen Ray Society, Philadelphia, PA. April 7, 2005. Jungreis CA. A primate model of reversible cerebral ischemia. Temple University Neuroscience Seminar. Philadelphia, PA. April 26, 2005. Jungreis CA. Cerebral Ischemia. Temple University Neuroscience Grand Rounds. Philadelphia, PA. October 6, 2006. Jungreis CA. Emergent Neuroradiologic Evaluations. Siemens Medical Solutions USA: CT Division, 51 Valley Stream Parkway, Malvern, PA 19355 (Coordinator - Praveen Nadkarni MD (610) 448-1692, Fax (610) 448-1565, [email protected] ), April 19, 2007. Jungreis CA. Cerebral Physiology and Interventional Neuroradiology. 2009 seminars for the Neuroscience Program, Temple University. February 25, 2009. Jungreis CA. Interventional Neuroradiology. Keynote Speaker: Carmen Lecturer at the Minnesota Radiology Society Vascular Conference. Mayo Clinic, Rochester, MN, November 7, 2009. Jungreis CA. Balloon Test Occlusion in the Skull Base patient. Presented at the 25th Anniversary of the Skull Base Center at the University of Pittsburgh Medical Center (UPMC). November 17, 2012.

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Refresher or CME courses: Faculty at annual meeting of Center for Cranial Base Surgery.

Lecture entitled "The Role of the Interventional Neuroradiologist." Pittsburgh, September, 1987.

International Symposium on Cranial Base Surgery, Pittsburgh, PA,

September 1988. Faculty member. Lecture entitled "The Role of Embolization in Skull Base Surgery."

Jungreis CA. "Tumor Embolization." Faculty and lecturer at

Cranial Base Surgery: Practical Applications Workshop. Sponsored by the Center for Cranial Base Surgery. Pittsburgh, June 1990.

Cranial Base Microsurgery and Radiosurgery Workshop. Faculty and

Lecturer. Lecture entitled "Balloon Test Occlusion." Sponsored by the University of Pittsburgh School of Medicine and the Center for Cranial Base Surgery. Pittsburgh, PA - May 11-14, 1992.

Jungreis CA. "Balloon Test Occlusion of the internal carotid

artery." Faculty and lecturer at The Decade of the Brain Conference. Sponsored by the George Washington University Neurological Institute, Washington, DC. September 11-15, 1993.

Cranial Base Microsurgery and Radiosurgery Workshop. Faculty and

Lecturer. Lecture entitled "Balloon Test Occlusion." Sponsored by the University of Pittsburgh School of Medicine and the Center for Cranial Base Surgery. Pittsburgh, PA - September 22-25, 1993.

Jungreis CA. Moderator and invited speaker at the symposium

entitled "Peripheral Vascular Disease: new horizons in patient management". Presentation entitled "Thrombolysis of acute stroke". Sponsored by Abbott Laboratories and the University of Pittsburgh Medical Center. Pittsburgh, PA, November 9, 1994. [Fred Howayeck of Access Medical Communications is coordinator - (708)-550-0090. Marshall Webster and Al Zajko were co-chairman.]

Jungreis CA. Interventional neuroradiology in acute stroke. CME

course on Acute Stroke sponsored by the University of Pittsburgh Medical Center, Johnstown, PA, June 26, 1995.

Jungreis CA. Interventional Neuroradiology and the impact on

nursing care. Faculty and lecturer at the conference

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51CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

entitled "Brainstorms: neuro trends in the 90's" (an update on diseases of the central nervous system). Sponsored by the center for continuing medical education at the University of Pittsburgh Medical Center. Pittsburgh, PA, September 18, 1995.

Jungreis CA. Current options for management of acute stroke.

The second annual symposium on peripheral vascular disease: new horizons in patient management. Course directors Drs. M. Webster and A.B. Zajko, University of Pittsburgh Medical Center. Pittsburgh, PA, February 28, 1996.

Jungreis CA. Thrombolysis in acute stroke. Sixth annual meeting

on vascular disease entitled "Cerebrovascular Disease". Sponsored by the Sewickley Valley Hospital. Pittsburgh, PA, April 17, 1996.

Jungreis CA. CT Angiography and Cerebrovascular Disease.

Faculty and speaker at UPMC sponsored Stroke Course, Pittsburgh, PA, September 20, 1996.

Jungreis CA. Endovascular intervention in Stroke. Faculty and

speaker at UPMC sponsored Stroke Course, Pittsburgh, PA, September 20, 1996.

Jungreis CA. Endovascular intervention in cerebrovascular

disease. CME Course on Stroke entitled "Brain Attack: Stroke Therapy 1997". Northwest Medical Center, Franklin, PA, Dr. James McLoughlin presiding. April 25, 1997.

Jungreis CA. Xenon CT Cerebral Blood Flow in the management of

cerebrovascular disease. Presented at the conference entitled "The Brain Microvasculature: clinical applications for neurologists and neurosurgeons." Lecturer and faculty at this conference organized by The Buffalo General Hospital and the Departments of Neurosurgery and Neurology at the State University of New York at Buffalo School of Medicine. May 3-4, 1997, Buffalo, NY.

Jungreis CA. Xenon CT Cerebral Blood Flow: a

neuroradiological/neurointerventional perspective. Lecturer and faculty at the 1997 Fourth International Conference on Xenon CT CBF. Baylor College of Medicine Department of Neurology and the Salzburg Conference on Cerebrovascular Disease (Chairman - John Stirling Meyer, MD, Professor of Neurology, Baylor College of Medicine). Houston, Texas, June 10-13, 1997.

Jungreis CA. Relative merits of Xenon CT CBF, SPECT CBF, PET,

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52CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

and MRI perfusion/diffusion in acute stroke. Special Panel discussion at the 1997 Fourth International Conference on Xenon CT CBF. Baylor College of Medicine Department of Neurology and the Salzburg Conference on Cerebrovascular Disease (Chairman - John Stirling Meyer, MD, Professor of Neurology, Baylor College of Medicine). Houston, Texas, June 10-13, 1997.

Jungreis CA. "Brain Attack". The Advanced Cardiac Life Support

Providers Course. University of Pittsburgh Medical Center - St. Margaret. Pittsburgh, PA, June 26, 1997.

Jungreis CA. Neuroradiologic intervention: stents and

angioplasty. University of Pittsburgh Medical Center Continuing Medical Education Course entitled "Stroke Update-1997". Faculty and lecturer. September 12, 1997, Pittsburgh, PA.

Jungreis CA. Magnetic resonance angiography. University of

Pittsburgh Medical Center Continuing Medical Education Course entitled "Stroke Update-1997". Faculty and lecturer. September 12, 1997, Pittsburgh, PA.

Jungreis CA. Stroke. University of Pittsburgh Medical Center

Continuing Medical Education Tele-medicine Course. Pittsburgh, PA. October 17, 1997.

Jungreis CA. "Brain Attack". The Advanced Cardiac Life Support

Providers Course. University of Pittsburgh Medical Center - St. Margaret. Pittsburgh, PA, January 10, 1998.

Jungreis CA. Angiographic evaluation of lesions of the head and

neck. Masters in Otolaryngology Meeting. Sponsored by the University of Pittsburgh Medical Center, Department of Otolaryngology (Jonas Johnson, MD, meeting chairman). March 11, 1998, Snowmass, Colorado.

Jungreis CA. Use of Cerebral Blood Flow in Interventional

Neuroradiology. "How to" Session speaker, organizer and moderator at the Annual Meeting of the American Society of Neuroradiology (ASNR), Philadelphia, May 18, 1998.

Jungreis CA. Imaging of the Acute Stroke. Faculty and Lecturer

at the Acute Stroke Management Workshop sponsored by the American Academy of Neurology. Pittsburgh, PA, May 16, 1998.

Jungreis CA. "Brain Attack". The Advanced Cardiac Life Support

Providers Course. University of Pittsburgh Medical Center - St. Margaret. Pittsburgh, PA, January 10, 1998.

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Jungreis CA. Angiographic evaluation of lesions of the head and

neck. Masters in Otolaryngology Meeting. Sponsered by the University of Pittsburgh Medical Center, Department of Otolaryngology (Jonas Johnson, MD, meeting chairman). March 11, 1998, Snowmass, Colorado.

Jungreis CA. Use of Cerebral Blood Flow in Interventional

Neuroradiology. "How to" Session speaker, organizer and moderator at the Annual Meeting of the American Society of Neuroradiology (ASNR), Philadelphia, May 18, 1998.

Jungreis CA. Imaging of the Acute Stroke. Faculty and Lecturer

at the Acute Stroke Management Workshop sponsered by the American Academy of Neurology. Pittsburgh, PA, May 16, 1998.

Jungreis CA. Emergent imaging and endovascular interventions in

acute stroke. Stroke update course sponsered by University of Pittsburgh Medical Center, Pittsburgh, PA, October 30, 1998.

Jungreis CA. XeCT Cerebral Blood Flow in Acute Stroke. Refresher

Course at the Radiological Society of North America (RSNA) Annual Meeting, Chicago, December 2, 1998.

Jungreis CA. XeCT Cerebral Blood Flow in Subarachnoid hemorrhage

and vasospasm therapy. Refresher Course at the Radiological Society of North America (RSNA) Annual Meeting, Chicago, December 2, 1998.

Jungreis CA. Emergent intervention on the intracranial arteries

during acute stroke. Invited speaker at the 1999 Joint Meeting of the AANS/CNS section on cerebrovascular surgery and the ASITN. Nashville, Tennessee, February 3, 1999.

Jungreis CA. Lecturer and faculty at the Stable Xenon Cerebral

Blood Flow Course. University of Pittsburgh Medical Center, Pittsburgh, PA February 25-27, 1999. (H. Yonas, coordinator).

Jungreis CA. Xenon CT for evaluation of acute infarction. Focus

session entitled Perfusion Imaging. 1999 Annual Meeting of the American Society of Neuroradiology (ASNR). San Diego, CA, May 25,1999.

Jungreis CA. Lecturer and faculty at the Stable Xenon Cerebral

Blood Flow Course. University of Pittsburgh Medical Center, Pittsburgh, PA July 23-24, 1999. (H. Yonas, coordinator).

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Jungreis CA. XeCT Cerebral Blood Flow in Acute Stroke. Refresher Course entitled "Neurologic Interventions: Endovascular Treatment of Acute Cerebral Ischemia" at the Radiological Society of North America (RSNA) Annual Meeting, Chicago, December 2, 1999.

Jungreis CA. XeCT Cerebral Blood Flow in Subarachnoid hemorrhage

and vasospasm therapy. Refresher Course entitled "Neurologic Interventions: Endovascular Treatment of Acute Cerebral Ischemia" at the Radiological Society of North America (RSNA) Annual Meeting, Chicago, December 2, 1999.

Jungreis CA. XeCT Cerebral Blood Flow in Subarachnoid hemorrhage

and vasospasm therapy. Joint Meeting of the American Society of Interventional and Therapeutic Neuroradiology (ASITN) and The Section on Cerebrovascular Surgery of the American Association of Neurological Surgeons (AANS) and the Congress of Neurological Surgeons (CNS), New Orleans, La., February 9, 2000. (Drs. Thomas R. Tomsick and Warren R. Selman, program organizers.)

Jungreis CA. Lecturer and faculty at the Stable Xenon Cerebral

Blood Flow Course. University of Pittsburgh Medical Center, Pittsburgh, PA March 24, 2000. (H. Yonas, coordinator).

Jungreis CA. Cerebral Blood Flow in the triage for acute

ischemia. "How to" session at the Year 2000 Annual Meeting of the American Society of Neuroradiology (ASNR). Atlanta, Georgia, April 4, 2000.

Jungreis CA. Xenon CT Cerebral Blood Flow in the triage for

acute stroke intervention. Focus session entitled "Stroke". Invited speaker at the Year 2000 Annual Meeting of the American Society of Neuroradiology (ASNR). Atlanta, Georgia, April 4, 2000.

Jungreis CA. Fifth Annual Symposium on Applied Physiology of the

Peripheral Circulation: cerebral blood flow, mechanisms of ischemia, diagnosis, and therapy. Scientific committee - Michael Pinsky, chairman. Pittsburgh, PA, June 9-10, 2000.

Jungreis CA. Triage of the acute stroke patient. "Emerging

Interventional Therapies: Stroke Conference" sponsored jointly by the Society of Cardiovascular and Interventional Radiology (SCVIR), the American Society of Interventional and Therapeutic Neuroradiology (ASITN), and the American Society of Neuroradiology (ASNR), Washington, DC, October 16, 2000. (Program chairman - Dr. Buddy Connors 703-698-3030.)

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Jungreis CA. Imaging of acute stroke. Stroke Update 2000.

Faculty and lecturer. UPMC annual course. Pittsburgh, PA, November 10, 2000.

Jungreis CA. Ischemic stroke and vasospasm. Interventional

Neuroradiology Session in the Categorical Course at the Annual Meeting of the Radiological Society of North America (RSNA), Chicago, November, 27, 2000. (Tom Tomsick 513-584-7544).

Jungreis CA. Ischemic stroke and vasospasm. Refresher course at

the Annual Meeting of the Radiological Society of North America (RSNA). Chicago, Illinois. November 26, 2001.

Jungreis CA. Intraarterial thrombolysis for acute stroke. UPMC

Stroke Institute Update 2001. Pittsburgh, PA, October 12, 2001.

Jungreis CA. Imaging in Stroke. STROKE: Medical perspectives

and therapeutic interventions. Hillside Rehabilitation Hospital, Warren, Ohio. October 5, 2001.

Jungreis CA. Interventional management of stroke. Course

entiltled ‘Stroke Update’ sponsored by the UPMC Health System Stroke Institute. Nemacolin Woodlins, PA, June 27, 2002.

Jungreis CA. Interventional management of stroke. Course

entiltled ‘Stroke Update’ sponsored by the UPMC Health System Stroke Institute. Meadville, PA, September 13, 2002.

Jungreis CA. Ischemic stroke and vasospasm. Refresher course at

the Annual Meeting of the Radiological Society of North America (RSNA). Chicago, Illinois. December 4, 2002.

Jungreis CA. Ischemic stroke and vasospasm. Refresher course at the Annual Meeting of the Radiological Society of North America (RSNA). Chicago, Illinois. December 5, 2003. Jungreis CA. Faculty and Lecturer. “Imaging in Stroke”. University of Pittsburgh Medical Center Stroke Institute Conference. Pittsburgh, PA. October 13, 2006. Jungreis CA. “Radiology Research”. Temple Research Course, Henry Parkman, MD, course director. December 7, 2006. Philadelphia, PA Jungreis CA. Stereotactic Radiosurgery with the Gamma Knife.

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Noon CME Course. Department of Radiology, Temple University Hospital. Philadelphia, PA. February 20, 2007. Jungreis CA. The physiology of Interventional Neuroradiology. Noon CME Course. Department of Radiology, Temple University Hospital. Philadelphia, PA. July 24, 2007. Other: Jungreis CA. Noon Conference Lecture Series for Radiology

Residents on Brain Tumors, Spinal Tumors and Neuroradiology Board Review, New York University Medical Center, 1984, 1985, 1986.

Jungreis CA. "Neuroradiologic Evaluation of the Brain-Injured

Patient." Presented at the December 1986 Meeting of Critical Care Medicine Lecture Program, Presbyterian-University Hospital, Pittsburgh, PA.

Pittsburgh NMR Institute. Monthly lectures on Radiologic

Evaluation of C.N.S. Disease. (1987-1988) Jungreis CA. "Magnavist in MRI." Lecture sponsored by

Pittsburgh Neuroradiology Society and Berlix. Pittsburgh, PA. September 22, 1988.

Stroke Update. University of Pittsburgh Health Sciences Center

Teleconference for Continuing Education. September 28, 1988.

"Treatment of Stroke: Radiographic Evaluation"; in Symposium on

Stroke with Guest Lecture by Henry J. Barnett, M.D. Sponsored by University of Pittsburgh School of Medicine. February 17, 1989.

Jungreis CA. "The Radiology of Stroke: Angiography, CT and MR."

Postgraduate Course on Cerebrovascular Disease - Stroke Prevention and Management. Sponsored by the School of Medicine, University of Pittsburgh, September 22, 1989.

Jungreis CA. Panelist at the Annual Meeting of the North

American Skull Base Society. Los Angeles, February 1990. Jungreis CA. "MR of the Brain." Visiting lecturer at South Side

Hospital, Pittsburgh, PA, April 4, 1990.

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Jungreis CA. "Current State of CT, MR and Angiography in Stroke." Presented at the Stroke Prevention and Management Course. Sponsor - Center for Continuing Education University of Pittsburgh. Pittsburgh, PA, September 28, 1990.

Moderator. Interventional Neuroradiology. Annual meeting of the

North American Skull Base Society. Lake Buena Vista, Florida, February 27-March 3, 1991.

Jungreis CA. "Current Strategies for the treatment of Carotid

Artery Disease - Neuroradiologic Evaluation." Telecommunication Conference sponsored by the University of Pittsburgh Center for Continuing Education in the Health Sciences. Pittsburgh, PA, May 22, 1991.

Jungreis CA. "Update of Angiography, CT and MR." Treatment and

Prevention of Stroke--1991. Course sponsored by the University of Pittsburgh School of Medicine. 10/25/91 - Faculty and Lecturer.

Jungreis CA. "Update on Transient Ischemic Attacks." St. John

Medical Center, Steubenville, OH. 11/16/91. Panelist. Preoperative Assessment of the ICA. Third Annual

Meeting of the North American Skull Base Society, Acapulco, Mexico - February 15-20, 1992.

Jungreis CA. "Neuroradiology of Coma." Jameson Memorial

Hospital, New Castle, PA. Sponsored by the University of Pittsburgh Center for Continuing Education in the Health Sciences. 3/18/92.

Jungreis CA. "Interventional Neuroradiology." Grand Rounds at

Citizens General Hospital, New Kensington, PA. Sponsored by the University of Pittsburgh Center for Continuing Education in the Health Sciences. 4/21/92.

Panelist. Strategies for management and treatment of Brain AVMs.

Fourth Annual Neuroradiology Morbidity and Mortality Conference, Jackson Hole, WY. August 11-15, 1992.

Moderator of General Session. Fourth annual meeting of the North

American Skull Base Society, Scottsdale, Arizona, February 12-14, 1993.

Panelist. Current interventional concepts in cerebral

arteriovenous malformations. Presented at the 31st annual meeting of the American Society of Neuroradiology,

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Vancouver, May 14-20, 1993. Jungreis CA. "Introduction to Neuroradiology." Neuroscience,

The Mind. University of Pittsburgh Medical Center second year medical student course. August 30, 1993.

Jungreis CA. "Neuroradiology of Acute Strokes." Neuroscience, The Mind. University of Pittsburgh Medical Center second year medical student course. August 30, 1993.

Jungreis CA. "Imaging of Acute Stroke." Stroke Update

Conference. Sponsored by University of Pittsburgh Continuing Medical Education Department. November 5, 1993, Pittsburgh, PA.

Jungreis CA. "Endovascular interventions in Stroke." Stroke

Update Conference. Sponsored by University of Pittsburgh Continuing Medical Education Department. November 5, 1993, Pittsburgh, PA.

Jungreis CA. Moderator of the session entitled Radiologic

Diagnosis in Skull Base Disease at the 1994 Joint Annual Meeting of the German and North American Skull Base Societies. February 20, 1994, Lake Buena Vista, Florida.

Jungreis CA. Panelist at the session entitled Radiologic

Diagnosis in Skull Base Disease at the 1994 Joint Annual Meeting of the German and North American Skull Base Societies. February 20, 1994, Lake Buena Vista, Florida.

Daily instruction of fellows, residents, and medical students in

neuroradiology. This includes angiography, interventional neuroradiology, myelography, CT, and MR.

Faculty and Lecturer in the University of Pittsburgh MRI

Fellowships and Technologist Educational Programs (4 courses per year).

Jungreis CA. Panelist at session entitled "Miscellaneous".

Interventional Neuroradiology Peer Review Conference. Jackson Hole, Wyoming, July 9, 1994.

Jungreis CA. Brain imaging in Psychiatric disease and dementias.

Western Psychiatric Institute and Clinic (WPIC) Resident Course. May 27, 1994, August 29, 1994, October 12, 1994, and April 17, 1995, Pittsburgh, PA. Coordinator - Dr. Mayada Akil (pager 565-8334; office 624-9913).

Jungreis CA. Suprasellar tumors. Noon conference for Radiology

residents. UPMC, Pittsburgh, PA, December 19, 1994.

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Jungreis CA. Moderator of Scientific Session at the annual

meeting of the North American Skull Base Society, February 19,1995, Naples, Florida.

Jungreis CA. Brain imaging in Psychiatric disease and dementias.

Western Psychiatric Institute and Clinic (WPIC) Resident Course. April 17 and December 21, 1995, Pittsburgh, PA. Coordinator - Dr. Mayada Akil (pager 565-8334; office 624-9913).

Jungreis CA. Panel on Radiologic Diagnosis at the 2nd

International Skull Base Congress and the 7th Annual Meeting of the North American Skull Base Society, San Diego, CA, June 29 - July 4, 1996.

Jungreis CA. Vascular tumors of the head and neck. Panelist at

the 4th International Conference on Head and Neck Cancer, July 28 -August 1, 1996, Toronto, Canada.

Jungreis CA. Panelist for Tumors Session. 9th Interventional

Neuroradiology Peer Review Conference, Jackson Hole, Wyoming, August 2, 1996.

Jungreis CA. Panelist for the session entitled Thrombolysis and

Angioplasty. Interventional Neuroradiology Peer Review Conference. Jackson Hole, Wyoming, August 4, 1995.

Jungreis CA, Knepper L. Endovascular thrombolytic therapy for

cerebral deep venous thrombosis. Neurology Grand Rounds, UPMC, Pittsburgh, PA, January 31, 1996.

Jungreis CA. Brain imaging in Psychiatric disease and dementias.

Western Psychiatric Institute and Clinic (WPIC) Resident Course. 1996, Pittsburgh, PA. Coordinator - Dr. Mayada Akil (pager 565-8334; office 624-9913).

Jungreis CA. Infections and inflammations of the brain. MR

Course. UPMC Department of Radiology. University of Pittsburgh, Pittsburgh PA, February 4, 1996.

Jungreis CA. Infections and inflammations of the spine. MR

Course. UPMC Department of Radiology. University of Pittsburgh, Pittsburgh PA, February 4, 1996.

Jungreis CA. MR imaging and the Cardiovascular Health Study.

Pittsburgh, PA, April 28, 1996.

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Jungreis CA. Interventional Neuroradiology and Juvenile Angiofibromas. Grand Rounds for the Dept. of Otolaryngology at the University of Pittsburgh Medical Center, Pittsburgh, PA, May 21, 1996.

Jungreis CA. Moderator at UPMC sponsored Stroke Course,

Pittsburgh, PA, September 20, 1996. Jungreis CA. Infections and inflammations of the brain. MR

Course. UPMC Department of Radiology. University of Pittsburgh, Pittsburgh PA, October 15, 1996.

Jungreis CA. Infections and inflammations of the spine. MR

Course. UPMC Department of Radiology. University of Pittsburgh, Pittsburgh PA, October 15, 1996.

Jungreis CA. Stroke (part 1). In service lecture for radiology

technologists. UPMC Department of Radiology. University of Pittsburgh, Pittsburgh, PA, February 13, 1997.

Jungreis CA. Stroke (part 2). In service lecture for radiology

technologists. UPMC Department of Radiology. University of Pittsburgh, Pittsburgh, PA, February 13, 1997.

Jungreis CA. Thrombolysis in acute stroke. Grand Rounds at St.

Margarets Memorial Hospital, Pittsburgh, PA, June 26, 1997. Jungreis CA. Moderator for the session entitled Test Occlusion

Complications. The 10th Annual Interventional Neuroradiology Peer Review Conference. August 1, 1997. Jackson Hole, Wyoming.

Jungreis CA. Interventional Neuroradiology. Grand Rounds for the

Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA, April 1, 1998.

Jungreis CA. Interventional Neuroradiology, Part II. Grand

Rounds for the Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA, May 6, 1998.

Jungreis CA. Panelist for the Aneurysm I Complication Cases

Session. 11th Annual Interventional Neuroradiology Peer Review Conference. Jackson, Wyoming. July 7, 1998.

Jungreis CA. Brain imaging in Psychiatric disease and dementias.

Western Psychiatric Institute and Clinic (WPIC) Geriatric Fellowship Course (Jules Rosen). Pittsburgh, PA. October 21, 1998.

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Jungreis CA. Imaging of the Acute Stroke. Grand Rounds at Butler Memorial Hospital, Butler, PA, December 14, 1998.

Jungreis CA. Moderator. 1999 Interventional Neuroradiology Peer

Review Course. Jackson Hole, Wyoming, July 31, 1999. Jungreis CA. Neuroimaging in cerebrovascular disease. Lecture

to the third year medical students at UPMC as part of their neuroscience clerkship. Pittsburgh, PA, September 13, 1999.

Jungreis CA. MR imaging in dementia. Lecturer in the WPIC

Geriatric Psychiatry Fellowship Course. University of Pittsburgh Medical Center, Pittsburgh, PA, October 20, 1999. (Jules Rosen, MD, course director, 624-8189).

Jungreis CA. Moderator at scientific session of the 38th Annual

Meeting of the American Society of Neuroradiology (ASNR), Atlanta, Georgia, April 2-8, 2000.

Jungreis CA. Moderator for session entitled "Chordomas and

chondrosarcomas" at the annual meeting of the North American Skull Base Society (NASBS) Meeting, Scotsdale, Arizona, March 20, 2000.

Jungreis CA. Moderator for session entitled "Angioplasty and

Stent", at the Thirteenth Annual Interventional Neuroradiology Peer Review Conference, Jackson Hole, Wyoming, July 27, 2000.

Jungreis CA. Ischemic Stroke Therapy. Moderator at a focus

session of the 39th Annual Meeting of the American Society of Neuroradiology (ASNR), Boston, MA, April 25, 2001.

Special Course Director for the Luncheon Seminar at the Annual

Meeting of the Section on Cerebrovascular Surgery of the American Association of Neurological Surgeons (AANS) and the Congress of Neurological Surgeons (CNS). Dallas, Texas. February 5, 2002.

Moderator at the Oral Session of the Annual Meeting of the

Section on Cerebrovascular Surgery of the American Association of Neurological Surgeons (AANS) and the Congress of Neurological Surgeons (CNS). Dallas, Texas. February 5, 2002.

Panelist, Angioplasty and/or stent placement session. 2002

Annual Interventional Neuroradiology Morbidity and Mortality Conference, Jackson Hole, Wyoming, August 1, 2002.

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62CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Moderator at the 41st Annual Meeting of the American Society of Neuroradiology (ASNR). Interventional Neuroradiology: arteriovenous malformations, fistulas, and aneurysms. Washington, DC. May 2, 2003. Jungreis CA. Interventional neuroradiology and functional imaging of acute cerebral ischemia. Neuroscience Grand Rounds. Temple University Hospital. Philadelphia, PA. January 23, 2004. Jungreis CA. Session Moderator. Arteriovenous Fistulas. 17th Annual Interventional Neuroradiology Conference. Jackson Hole, Wyoming. July 29, 2004. Jungreis CA. Cerebral Blood Flow and Vasospasm in Subarachnoid Hemorrhage from Aneurysm Rupture. Neuroscience Grand Rounds. Temple University Hospital. Philadelphia, PA. October 21, 2004. Moya-moya. Department of Medicine Grand Rounds, Temple

University, May 3, 2005. Stereotactic Radiosurgery with the Gamma Knife: implications for

the radiologist. Resident lecture, Department of Radiology, Temple University, September 27, 2005.

Jungreis CA. Co-Moderator: Breakfast Seminar entitled “Radiosurgery and Neuroradiological Advances”. The Annual Meeting of the North American Skull Base Society (NASBS), Phoenix, Arizona. February 17, 2006. Jungreis CA. Cerebral Blood Flow and Acute Stroke Therapy. Radiology Noon Lecture Series. July 25, 2006. Jungreis CA. Topics in Clinical Research Seminar Series. Use of Radiology and Radioisotopes in Clinical Research. Charles A. Jungreis, Chairman of Radiology and Kurt Bodison, Radiation Safety Officer. Thursday December 7, 2006. Temple University Hospital, Philadelphia, PA. Jungreis CA. Stereotactic Radiosurgery with the Gamma Knife. Noon CME Course. Department of Radiology, Temple University Hospital. Philadelphia, PA. February 12, 2008. Jungreis CA. Introduction to Radiology. Temple University School of Medicine Radiology Course 727. Lecture provided each rotation 2008-2010 (12 times per year). Jungreis CA. MR of the Brain and Spine. Department of

Neurology, Temple University. July 31, 2008.

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63CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Jungreis CA. MR of the Spine Part I. Department of Neurology,

Temple University. July 29, 2010. Jungreis CA. MR of the Spine Part I. Department of Neurology,

Temple University. August 26, 2010. RESEARCH: SEPTEMBER - JUNE 1974 Research Assistant Department of Chemistry Dartmouth College JUNE 1975 - SEPTEMBER 1976 Research Assistant JUNE 1977 - SEPTEMBER 1977 Cold Spring Harbor Laboratory Cold Spring Harbor, NY James D. Watson, Director JANUARY 1985 - JUNE 1986 Principal Investigator MR properties of tumors and tumor related cysts in the central nervous system. New York University Medical School 1986 - 1995 Co-Investigator Use of Endovascular Catheter Therapy (Surgical Neuroangiography) in the Treatment of Diseases of the Central Nervous System. Sponsor - Dept. of Radiology, Univ. of Pittsburgh. 1987 - 1988 Co-Investigator Elemental analysis of CNS tissue using ICP (Inductively Coupled Argon Plasma Atomic Emission Spectroscopy) and the MRI implications. Joseph L. Fabec, Pittsburgh Applied Research Center, University of Pittsburgh, Pittsburgh, PA. 1988 - 1990 Co-Investigator - In Vivo Radiobiology of Brainstem Stereotactic Radiosurgery.

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64CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Chief Investigator L. Dade Lunsford, M.D. 1988 - 1994 Use of Acrylic Tissue Adhesives in Treatment of CNS Tumors and Vascular Malformations. Sponsor - CRX Medical Inc. 1988 - 1990 Co-Investigator Angiostat, Collagen for Therapeutic Embolization. Sponsor - Target Therapeutics. 1988 - 2003 Co-Investigator North American Symptomatic Carotid Endarterectomy Trials (NASCET). Local P.I. - Lawrence R. Wechsler, M.D. Principal Investigators - Henry J. Barnett, M.D. and S.J. Peerless, M.D. 1988 - 1994 Principal Investigator. Hema for use in Balloon Embolizations. Sponsor - Department of Radiology, University of Pittsburgh. 1988 - 1994 Co-Investigator Use of Detachable Silicone Balloons in Therapeutic Embolizations of the Central Nervous System. Sponsors – Interventional Therapeutics Inc., and Dept. of Radiology, Univ. of Pittsburgh. 1989 - 1990 Co-Investigator - An Open Study of the Safety and Efficacy of Various Doses of BW tPA in Patients with Acute Stroke. Principal Investigator -Lawrence R. Wechsler, M.D. Sponsor - Burroughs - Wellcome 1989 - 1990 Co-Investigator - In Vivo Radiobiology of Stereotactic

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65CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Radiosurgery in the Rat. Principal Investigator- Eric Altschuler, M.D. 1989 - 1995 Co-Investigator Intracranial Angioplasty for the Treatment of Vasospasm Secondary to Subarachnoid Hemorrhage. Sponsor - Department of Radiology, University of Pittsburgh. 1989 - 1994 Co-Investigator Fluid Mechanics in Normal and Pathological States of the Cerebral Vasculature. Sponsors - Dr. Charles W. Kerber Labs and Dept. of Radiology, University of Pittsburgh. 1989 - 1995 Co-Investigator Correlation of Angiography, XeCT, and Clinical Outcome in Skull Base Tumor Surgery. Sponsor - Department of Neurosurgery, University of Pittsburgh. 1990 - 1991 Co-Investigator Correlation of Motor Evoked Potentials with Tomographic Images of the Brain. Sponsors - Departments of Neurosurgery and Radiology, University of Pittsburgh. 1990 - 1991 Co-Investigator Correlation of MR of the Brain with Neuropsychiatric Testing. Sponsor - Western Psychiatric Institute and Clinic, University of Pittsburgh. 1990 - 1991 Co-Investigator Preoperative MR Evaluation of Microvascular Compression of Cranial Nerves and of the Brainstem. Sponsor - Departments of

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66CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Neurosurgery and Radiology, University of Pittsburgh. 1990 - 1991 Co-Investigator (D. Oliver-Smith - PI). Modification of Intracranial Vasospasm secondary to subarachnoid hemorrhage in a rat model. Sponsor - Dept. of Neurosurgery, University of Pittsburgh. 1991 - 1993 Co-Investigator - An Open Study of the Safety and Efficacy of Various Doses of tPA in Patients with Acute Stroke. Principal Investigator -Lawrence R. Wechsler, M.D. Sponsor - Genentech 1991 - 1999 Intraarterial thrombolysis for treatment of acute stroke. Sponsor - Depts. of Radiology and Neurosurgery. (Co-investigators: CA Jungreis, LR Wechsler, H Yonas) 1991 - 1995 Comparison of SPECT and stable Xenon CT cerebral blood flow in balloon test occlusions of the internal carotid artery. (Co-investigators: divisions of neuroradiology and nuclear medicine.) 1991 - 1993 MR Angiography for Evaluation of Intracranial Aneurysms: Associations with Genetic Markers. P.I. - H. Yonas. Sponsor – Hearst foundation. Funding - Total over 2 years =$200,000; Radiology = $25,000. 1991-2006 Co-Investigator. Cardiovascular Health Study (CHS). Multicenter NIH sponsored study. Local P.I. - Lewis Kuller, M.D. NIH, IIC85082 06/01/88-03/31/95 - $2,487,787 TDC. Renewal to 5/31/2000 - $1,003,627. Renewal to 5/31/2005.

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67CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

1992-1994 Co-Investigator. Open-label Magnevist Injection Post-Marketing Surveillance Study. P.I. – David W. Johnson, M.D. Sponsor – Berlex Laboratories. 1993-1999 Brain tumor study group. Co-investigators are Mark Gilbert and Paul Kornblith. Supported by Pittsburgh Cancer Institute (PCI). 1994-1999 Co-principal investigator (P.I.- H Yonas, G Banks). Implementation of a teleradiology system to enhance consultative services between primary and secondary care hospitals and a tertiary care facility. NLM rfp/contract #BAA/RFP No. NLM 93-105/PSP $2,301,608. 1994-1999 Co-principal investigator (with LR Wechsler). Depts of Radiology and Neurology, UPMC. A prospective multicenter dose-ranging study of intra-arterial thrombolysis using recombinant prourokinase in acute middle cerebral artery distribution thromboembolic stroke. Sponsor - Abbott Laboratories. 1994-1997 Co-investigator (2.5% effort). Therapeutic studies of primary CNS malignancies in adults (PI - Mark R. Gilbert). 03/18/94-12/31/97 - $148,390 TDC. NCI. 1995-1997 Co-investigator. A Model of Aneurysmal Subarachnoid Hemorrhage in a Rhesus Monkey. Ed Nemoto, Howard Yonas. 1995-1997 Co-investigator. A feline (cat) facial nerve paralysis model (Bell's Palsy Model). 1995-1997 Co-investigator. A canine (dog) partial mandibular allograft model.

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68CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

1997-2002 Co-investigator. Peter Jannetta - P.I. Magnetic resonance imaging of the posterior fossa neurovascular relationships: a prospective study. 1997-2003 Safety Committee. Douglas Kondziolka - P.I. Single Center Open Label Observer Blinded Safety and Effectiveness and Long Term Evaluation of the Cerebral Placement of LBS-Neurons in 12 Patients with Substantial Fixed Motor Deficit following Lacunar Cerebral Infarction (neuron transplants). Funded by Layton Bioscience, Inc. ($415,355). 1997-2002 Co-investigator. Peter Jannetta - P.I. Non-insulin dependent diabetes mellitus: etiology and treatment, a prospective study. 1999-PRESENT Co-inventor and investigator. Shape memory polymer microcatheter. University of Pittsburgh and the Lawrence Livermore National Laboratories. Department of Energy (DOE) Grant 6/99. 1999-2001 Effects of ApoE on outcomes in TBI (Traumatic Brain Injury) adults. Co-investigator. NIH 9/1/1999 - 6/30/2001. 2001-2003 Co-investigator. Pilot study of MRI techniques for selecting patients for IV tPA therapy between 3-6 hours after stroke onset. 2001-2005 Co-investigator. Interventional

Management of Stroke (IMS). PI - Tom Tomsick. Data analysis continuing to Present.

2001-2003 Principal Investigator. EPAR, a new device for acute stroke intervention (Endovasix).

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69CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

2001-2002 Co-investigator. Comparison of CT perfusion to Xe/CT CBF in patients with acute stroke (PI- Steven Goldstein, MD). 2001-2003 Co-investigator. Neurovasix microcatheter for the mechanical lysis of thromboembolus in acute stroke. 2001-2002 Co-investigator. BATT Trial (Quantitative Cerebral Blood Flow in Acute Thrombolytic Therapy Trial). Dr. Steven Goldstein, PI. Salary support 10%. 2002-PRESENT Co-investigator with Fernando Boada and Edwin Nemoto. Change in sodium concentration in the brain of a high level non-human primate as determined by high field MR during cerebral ischemia. 2002-2003 Co-investigator. TriSpan Endovascular Coils for Treatment of Cerebral Aneurysms. Target/Boston Scientific. 2002-2003 Co-investigator. Matrix Endovascular Coils for Treatment of Cerebral Aneurysms. Target/Boston Scientific. 2003-2005 Co-investigator, with Howard Yonas

and Rhonda Pindzola. Expanding the window for thrombolytic therapy in acute stroke by CT based technologies. Grant application (5% effort) pending 2/28/2003.

2003-2005 Co-investigator, CREST (Carotid

Revascularization Endarterectomy versus Stent Trial).

2006-PRESENT Consultant on RO1 entitled “Thermal

and Salvageable Tissue Dynamics in Stroke”. PI – Dr. Edwin Nemoto. Application pending 1-17-2006.

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70CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

2006-PRESENT Co-investigator for NINDS

Consortium entitled “Ischemic Brain Damage and Triple/Single Quantum Sodium MRI”. PI – Dr. Edwin Nemoto. Application pending 1-17-2006.

2006–2007 TACIT (Transatlantic Asymptomatic

Carotid Intervention Trial), a prospective, multidisciplinary, multi-center, collaborative U.S. and E.U., unblinded, three-arm, randomized trial. CA Jungreis, local PI. (The U.S. Principal Investigator for TACIT is Barry Katzen, MD, of Baptist Cardiac & Vascular Institute, Miami, Florida and the E.U. Principal Investigator is Matthew Thompson, MD of Saint Georges Hospital, London, England.) NIH application pending 5-19-2006 (June 1, 2006 application deadline).

2006-PRESENT Co-investigator. Reversible Focal

Cerebral Ischemia in a Non-human Primate (Monkey): PET and MR analysis. PI – Edwin Nemoto. Salary support pending. NIH application made 6-1-2006.

SERVICE: Scientific Journals 1988 - PRESENT Reviewer - Radiology 1990 Reviewer - Stroke 1991 - 2011 Reviewer - Skull Base Surgery 1991 - 2009 Reviewer - Journal of Vascular and Interventional Radiology (JVIR)

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71CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

1992 - PRESENT Reviewer - American Journal of Neuroradiology (AJNR) 1995 - 2003 Reviewer - Journal of Computer Assisted Tomography (JCAT) 1997 - 2003 Reviewer - Journal of Neuro- Oncology 1998 - 2003 Reviewer - American Journal of Otolaryngology 1999 - 2009 Reviewer - Annals of Otology, Rhinology & Laryngology 1999 - PRESENT Editorial Board and Reviewer,

Journal of Neuroimaging. 2002 - 2003 Reviewer - Neuroradiology 2012 to Present Reviewer - Neurosurgery Other service National/International 1990 - 1992 Reviewer - Spinal Cord Research

Foundation Washington, DC 1993 - 1997 Bylaws Committee, North American

Skull Base Society 1994 - 2003 Nominating Committee, North

American Skull Base Society (re-elected 1996)

1997 Reviewer of scientific papers for

the Annual Meeting of the American Society of Neuroradiology and American Society of Head and Neck Radiology.

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72CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

1997 - 2004 American Society of Neuroradiology Task Force on Stroke (development of training guidelines and performance standards).

1998 - 2001 Board Member-at-Large, North

American Skull Base Society Board of Directors.

1998 - 2000 Scientific Committee for the Fifth

Symposium on Applied Physiology of the Peripheral Circulation: The Cerebral Circulation (Michael Pinsky, MD, director).

1999 - 2004 American Society of Neuroradiology

(ASNR) Task Force on Coding. 1999 American Society of Neuroradiology

(ASNR) program committee abstract reviewer for the Annual Meeting of the ASNR (Atlanta, May 2000).

2000 American Society of Neuroradiology

(ASNR) program committee abstract reviewer for the 39th Annual Meeting of the ASNR (Boston, April 2001).

2001 Reviewer for the American Academy

of Otolaryngology-Head and Neck Surgery Foundation, Inc. Renewal of Certification Examination Study Guide in Otolaryngology-Head and Neck Surgery. Jonas T. Johnson, MD, editor.

2001 Abstract Reviewer. 2002 Annual

meeting of the AANS (American Association Of Neurological Surgeons) and the ASITN (American Society of Interventional and Therapeutic Neuroradiology).

2001 Abstract Reviewer. 2002 Annual

meeting of the ASNR (American Society of Neuroradiology).

2002 Grant Reviewer. Biomedical Research

Center, Cell and Systems Research

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73CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Section, Agency for Science, Technology and Research. 250 North Bridge Tower, Singapore 179101 (phone 011 65 6826 6395).

2004 Abstract reviewer for the 43rd

Annual Meeting of the ASNR (American Society of Neuroradiology) held in cooperation with the ASFNR, ASHNR, ASPNR, ASSR and ASITN.

2005 Scientific Session Moderator for

the 43rd Annual Meeting of the ASNR (American Society of Neuroradiology) held in cooperation with the ASFNR, ASHNR, ASPNR, ASSR and ASITN. Toronto, Canada. May 21-27, 2005.

2005-2008 IDX ImageCast Advisory Board.

Burlington, Vermont. 2005 Consultant for Boston Scientific

Research and Development (Michael Wallace – Director).

2005 Abstract Reviewer. ASNR 44th

Annual Meeting. San Diego, CA April 29 - May 05, 2006 2005-Present DSMB (Data Safety Monitoring Board)

NINDS/NIH ALIAS Trial 2005-Present DSMB (Data Safety Monitoring Board)

NINDS/NIH IMS III Trial 2006 Outstanding Presentation Reviewer

2006 ASNR Annual Meeting 2006 AHA (American Heart Association)

2006 Annual Meeting Abstract Reviewer.

2006-2012 Advisor for Synthes Spine Company,

L.P. by serving as a participant in the Clinical Events Committee of the SyntheCel Dura Replacement

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74CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Clinical Trial under the direction of Jack Jallo, MD who was the Chair of the Committee.

2007 Abstract Reviewer. ASNR 45th

Annual Meeting. Chicago, IL June 6-14, 2007.

2007-Present DSMB (Data Safety Monitoring Board)

NINDS/NIH ARUBA Trial 2008 Abstract Reviewer. ASNR 46th

Annual Meeting. New Orleans, LA. June 2-5, 2008.

2009 Abstract Reviewer. 47th Annual

Meeting of the American Society of Neuroradiology 2009 (ASNR). Vancouver, Canada. May 11-15, 2009.

2010 Abstract Reviewer. 2010 48th Annual

Meeting of the American Society of Neuroradiology (ASNR). Boston, MA. May 15-20, 2010.

2011 Abstract Reviewer. 2011 49th Annual

Meeting of the American Society of Neuroradiology (ASNR). Seattle, WA. June 5-10, 2011.

2010 to Present SCARD SIG (Strategic Initiative

Group) – Minimally Invasive Diagnosis and Therapy Committee. Co-chair.

2010 to Present SCARD SIG (Strategic Initiative

Group) – Low Dose Radiation Committee member.

2011 Scientific expert on the Radiology

grant review panel. FDA/ Office of Orphan Products Development

2012 Abstract Reviewer for the American

Society of NeuroRadiology (ASNR) 50th Annual Meeting, New York, April

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75CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

21-26, 2012. 2011 to Present CNAC (Comprehensive NeuroAids

Center) Internal Advisory Committee, Temple University School of Medicine.

University of Pittsburgh Medical Center 1987 - 2003 Member of the University of Pittsburgh Stroke Institute (formerly UPMC Stroke Center) University of Pittsburgh School of

Medicine 1988 - 2003 Member of the AVM Board University of Pittsburgh School of Medicine 1989 Faculty Reviewer (Radiology

Representative) for the ACGME (Advisory Committee of Graduate Medical Education)

Evaluation of Department of Neurological Surgery.

1992 - 1998 Curriculum Committee for

"Neuroscience, The Mind." University of Pittsburgh Medical Center, School of Medicine (second year medical student course).

1993 - 1998 Chief, Division of Neuroradiology,

Department of Radiology, University of Pittsburgh Medical Center.

1993 - 1998 Head of the Neuroradiology

Fellowship Training Program at the University of Pittsburgh Medical Center (Accredited by the ACGME -program #4234121057).

1994 - 2003 Scientific Advisory Committee for

the Functional Imaging Research Program (FIRP), University of

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76CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Pittsburgh Medical Center, Pittsburgh, PA.

1999 - 2003 University of Pittsburgh Medical

Center Department of Radiology Scientific Review Committee.

2001 Reviewer for the University of

Pittsburgh Office of Technology Management.

2001 Reviewer for the University of

Pittsburgh Center for Research in Chronic Disorders (CRCD). (Contact person Dr. Elizabeth A. Schlenk 412-624-4103 or [email protected].)

2001-2003 Department of Radiology

representative to the University of Pittsburgh Institutional Data and Safety Monitoring Board (IDSMB). [Monitor clinical trials as required by the NIH].

Temple University School of Medicine 2003-PRESENT Chairman of the Department of

Radiology, Temple University. Philadelphia, PA

2003-PRESENT Radiation Safety Committee. Temple

University, Philadelphia, PA. 2003-2004 Program Director Radiology Residency(ACGME Approved

program # 4204111173) Temple University 2004-PRESENT Temple University Physicians (TUP)

Finance and Personnel Committee 2005-2006 Temple University School of

Medicine Search Committee for the Chair of the Department of Neuroscience.

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77CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

2005-Present Technology Advisory Committee for Temple University Health System.

2005-Present Cephalon/Temple University

Neuroscience Seminar Committee. Seminar March 28, 2007.

2005-Present Appointed by CATA (Committee on

Academic and Trustee Appointments) to be a faculty representative on the Temple University search committee for the Dean of the College of Liberal Arts. Nominated by Betsy Leebron, Ph.D. Professor Broadcasting, Telecommunications and Mass Media Temple University 215-204-5401, 215-204-5402(fax)

2005-Present Medical Radiation Subcommittee in

the Radiation Safety Committee. Temple University, Philadelphia, PA.

2005-Present TUHS (Temple University Health

System) Peer Review Committee 2008 - Present Temple University School of

Medicine CTSA Writing Committee for Translational Research, a collaboration of the Basic Science and Clinical Departments (January 31, 2008, first meeting).

2008/06/10 – Present TUH Access Team – assembly of

leadership across disciplines to improve patient flow.

2008/10/01 Program Committee. Temple

University Functional Imaging Symposium. October 1, 2008.

2009 to Present Temple University Faculty Senate

Steering Committee 2010 to Present Temple University Office of

Development Committee 2011 to Present Temple University Hospital Joint

Operations Committee

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78CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

Local 1988 - 1989 Reviewer - Allegheny-Singer Research Institute Pittsburgh, PA 1991 - 1993 Administrative duties: Board member of SRT Radiologists,

P.C. Member of Investment Committee of

SRT Radiologists, P.C. 1991 - 1996 Consultant to the Allegheny County

Coroner 1993 - 1994 Reviewer - Ben Franklin Technology

Center of Western Pennsylvania Challenge Grant (Pennsylvania Department of Commerce).

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79CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

MISCELLANEOUS Patent: Co-inventor.

Shape Memory Polymer Actuator and Catheter US Patent # 6,740,094 B2 Date of Patent: May 25, 2004 (filed July 24, 2002).

Patent: Co-inventor. Shape Memory Polymer Actuator and Catheter U.S. Patent Number 7,291,154 IL-10492B/S-103920 Date of Patent: October 6, 2007 Honors and Awards: 1. 10-15-2007 2007 Radiology - Editor’s Recognition

Award for reviewing with Distinction. 2. 11-07-2007 Best Doctors Award Recognition 3. 2007-2008 Best Doctors in America List

4. 2009-02-27 W. Edward Chamberlain Professor of Diagnostic Imaging, Temple University School of Medicine

5. Best Doctors in America List 2011-2012 New programs initiated: 1. Intracranial aneurysm therapy via endovascular GDC coil

placement. UPMC. 2. Endovascular treatment of craniocervical atherosclerotic

disease, including angioplasty and stent placement in the carotid arteries. UPMC.

3. Head and Neck Cancer Immunotherapy via intraarterial

infusion of Ethiodol-Interleukin-2. UPMC. 4. University of Pittsburgh Stroke Institute. UPMC. Subject of television, newspaper or magazine articles: 1. Pittsburgh Post Gazette interview (1/26/96) and article by

Byron Spice. "New fight against aneurysms." February 12,

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80CHARLES A. JUNGREIS, M.D. CURRICULUM VITAE

1996. 2. Pittsburgh Post Gazette interview (8/28/96) and article by

Byron Spice. 3. Pittsburgh Magazine, April 2002, pp94-104. ‘The Best

Doctors in America.’ Based on data from Best Doctors Incorporated, Boston, MA.

4. Named to the list of “Best Doctors 2005-2006” (9/15/2005). 5. Selected as one of “America’s Top Radiologists” in the Guide

to America’s Top Radiologists: 2006 Edition. May 15, 2006.

Consumer’s Research Council of America 2020 Pennsylvania Avenue NW Suite 300-A Washington, DC 20006 6. 2008-02-01 Charles A. Jungreis. Stereotactic Radiosurgery

with the Gamma Knife. The Doctors’ Channel (On-line medium). David Best, MD, MBA, President, The Doctor's Channel

7. 2008-09-18 KYW Radio. fMR and Brain Imaging. 8. 2008-09-18 KHYY Radio. fMR and Brain Imaging. Subject of television commercials: 1. Shot on location at UPMC, August 6, 1996. 2. Shot on location at UPMC, March 12, 1997 3. Shot on location at UPMC, December 18, 2000 4. Temple Lifelines, shot on location at Temple University,

CBS, March 31, 2005.