curriculum vitae grace elizabeth pluhar, dvm, phd ...€¦ · grace elizabeth pluhar, dvm, phd,...

CURRICULUM VITAE

Grace Elizabeth Pluhar, DVM, PhD, Diplomate ACVS

Department of Veterinary Clinical Sciences College of Veterinary Medicine

1352 Boyd Avenue C352 University of Minnesota

Saint Paul, Minnesota 55108 Telephone: (612) 625-1162 office

Telefax (612) 624-0751 Email: [email protected]

Education:

1978 BS Northern Illinois University DeKalb, Illinois

1979 MS Northern Illinois University DeKalb, Illinois Thesis:Factors Affecting the Interconversion of Ornithine Decarboxylase Formsin Physarum polycephalum

1989 DVM Oregon State University Corvallis, Oregon

1995 MS Washington State University Pullman, WashingtonThesis:Effect of Acute Unilateral Transverse Venous Sinus Occlusion on Intracranial Pressure in Normal Dogs

1999 PhD University of Wisconsin Madison, Wisconsin Thesis: Comparison of Methods of Soft Tissue Attachment to Proximal Femoral Allografts for Hip Revision

Postgraduate Training:

1989-1990 Internship, Animal Medical Center, New York, NY

1992-1995 Residency, Small Animal Surgery, Washington State University, Pullman, WA

1993 AO/ASIF Basic Canine Course, The Ohio State University, Columbus, OH

1997 Bone and Hematopoietic and Immune Systems Scientific Workshop, NIH, Bethesda, MD

1997 AO/ASIF Advanced Canine Course, The Ohio State University, Columbus, OH

1999 Tibial Plateau Leveling Seminar, Slocum Enterprises, Eugene, OR

1999 Canine Arthroscopy Course, Colorado State University, Fort Collins, CO

December 15, 2013

mailto:[email protected]

mailto:[email protected]

PLUHAR, G. Elizabeth

2000 SA Circular External Skeletal Fixation, IMEX Veterinary, Inc, Dallas, TX

2000 Contemporary Issues in Canine Hip Replacement, San Diego, CA

2002 Cell-based Treatment and Tissue Engineering, Case Western Reserve University,Cleveland, OH

2005 Supervisor and Program Director Training, Saint Paul

2005 Dual Energy Xray Absorptiometry (DEXA) Operator Training, Chicago. IL

2005 Competitive Grant Writers’ Seminar and Workshop, Minneapolis

2005 ORS/OREF Grant Writing Workshop, Washington, DC

2006 Hill’s Canine Osteoarthritis Symposium, Orlando, FL

2007 SAS: Introduction to Programming Concepts, Minneapolis

2007 SAS Programming I: Essentials, Minneapolis

2007 Best Practices Institute: Excellence in Health Professions Education, Minneapolis

2008 Best Practices Institute: Excellence in Health Professions Education, Minneapolis

2009 Skippy Frank Translational Medicine Multidisciplinary Cancer Conference, Palo Alto, CA

2009 Society for CNS Interstitial Delivery of Therapeutics Conference, Cleveland, OH

2009 Faculty Member as Mentor: Best Practices in the Successful Mentoring of Graduate Students, Minneapolis, MN

2010 Challenges, controversies and opportunities in glioblastoma multiforme: A targeted perspective, Society for Neuro-Oncology meeting, Montreal, Canada

2011 Brain-Heart Symposium, University of Minnesota, Minneapolis, MN

2011 Good Laboratory Practices Training Course, West Coast Quality Training Institute, Pacific Rim Consulting, Inc. Minneapolis, MN

2012 CVM Teaching Seminar, Center for Teaching and Learning, Saint Paul, MN.

2013 2nd Skippy Frank Translational Medicine Multidisciplinary Cancer Conference, Palo Alto, CA

2015 The Role of Clinical Studies for Pets with Naturally Occurring Tumors in Translational Cancer Research, Institute of Medicine Workshop, Washington DC

December 15, 2013 2

Veterinary Licensure: 1989-2002 Washington (Accreditation, 1989) 1989-2000 New York


2015 Primer on Tumor Immunotherapy and Cancer Immunotherapy, Society for Immunotherapy of Cancer, National Harbor, Maryland

Faculty Appointments/Positions:

1990-1991 Private Practitioner, Heartarrow Veterinary Services, Veradale, WA

1991-1992 Instructor, Community Practice, Department of Veterinary Clinical SciencesCollege of Veterinary Medicine, Washington State University

1997 Instructor, Small Animal Orthopedics, Department of Surgical SciencesSchool of Veterinary Medicine, University of Wisconsin-Madison

1999-2003 Assistant Professor, Department of Clinical Sciences, College of VeterinaryMedicine and Biomedical Sciences, Colorado State University

2003- 2008 Assistant Professor, Department of Small Animal Clinical SciencesCollege of Veterinary Medicine, University of Minnesota

2004-2006 Consultant, Research and DevelopmentStryker Biotech, Hopkinton, MA

2004-2012 Consultant, Research and DevelopmentStryker Orthopaedics, Mahwah, NJ

2006-2012 Consultant, Active Implants Corporation, Memphis, TNConsultant, Surpass Incorporated, Osceola, WI

2008-2015 Associate Professor, Department of Veterinary Clinical SciencesCollege of Veterinary Medicine, University of Minnesota

2009-2012 Consultant, Denali Medical, Eden Prarie, MN Consultant, Medtronic, Minneapolis, MN

2012-present Consultant, Invibio Inc., West Conshohocken, PA

2015-present Professor, Department of Veterinary Clinical SciencesCollege of Veterinary Medicine, University of Minnesota

Specialty Certification:

1999 Certified, American College of Veterinary Surgeons (ACVS)

December 15, 2013 3

1989 American Veterinary Medical Association (AVMA) 1993 American Association of Veterinary Clinicians (AAVC) 1999 International Society of Limb Salvage (ISOLS) 1999 Orthopaedic Research Society (ORS)

Membership committee – m ember (2008-2012), Vice Chair 2009, Chair 2010, ex officio Chair 2011 Volunteer Appointment Committee – m ember (2009-2010)

1999 American College of Veterinary Surgeons (ACVS)

Research committee – m ember (2007-2010), Assistant Chair 2008-2009, Chair 2009-2010

2000 Veterinary Orthopedic Society (VOS)

Scientific Program committee (2008-2010), Assistant Chair 2008-2009, Chair 2010-2011

2000 American Association for the Advancement of Science (AAAS) 2004 Minnesota Veterinary Medical Association (MVMA) 2005 Cancer Center, University of Minnesota 2005 Biomedical Engineering Institute, University of Minnesota 2011-2014 World Veterinary Orthopedic Conference (WVOC), organizing committee for

2014 meeting, Neurosurgery sessions, Chair 2012-2013 International Conference on One Medicine One Science (iCOMOS). Organizing

committee 2012-present Neuro-Oncology Symposium. University of Minnesota, Organizing Committee 2013-present Brain Tumor Program, Executive board, University of Minnesota 2014-2019 Food and Drug Administration, Cellular, Tissue and Gene Therapy Advisory

Committee 2015 Comparative Brain Tumor Consortium, organizing committee, National Institutes

of Health National Cancer Institute


1997-2003 Wisconsin 2004-present Minnesota

Memberships, Board and Officer Positions in Professional and Scientific Societies:

December 15, 2013 4


Awards/Honors: 1977 Phi Sigma, National Biological Sciences Honorary, Northern Illinois University 1993 Dr. Lynn A. George Memorial Scholarship, College of Veterinary Medicine,

Washington State University 1994 Phi Kappa Phi, Washington State University 1994 Sigma Xi, Washington State University 1994 1st Place Resident Awards, American College of Veterinary Surgeons, Crystal

City, VA 1994 Dr. Lynn A. George Memorial Scholarship, College of Veterinary Medicine,

Washington State University 1994 Drs. Ghery Pettit and Jack D. Robinette Surgery Scholarship, College of

Veterinary Medicine, Washington State University 1995 Phi Zeta Society, Washington State University 1995 Drs. Ghery Pettit and Jack D. Robinette Surgery Scholarship, College of

Veterinary Medicine, Washington State University 1997 Travel Scholarship, International Society of Limb Salvage, New York, New York 1998 1st Place Pre-Doctoral Abstract Award, 1st Annual Department of Veterans Affairs

Rehabilitation Research and Development National Meeting, Washington D.C. 1999 Annual Dissertator Travel Award, Animal Health and Biomedical Sciences,

University of Wisconsin-Madison 1999 Travel Scholarship, International Society for Limb Salvage, Cairns, Australia 2000 2nd Place Faculty Oral Presentation, Phi Zeta Research Day, Colorado State

University 2002 William Harris Award (for outstanding work in orthopaedic research related to

the hip), Orthopaedic Research Society and the Harris Fellows Club 2003 Who’s Who in 20th Century America, Marquis’ Who’s Who Hall of Fame Inductee, Oak Lawn Community High School, Oak Lawn, IL 2003 1st Place Faculty Oral Presentation, Phi Zeta Research Day, Colorado State

University 2003 1st Place Faculty Poster Presentation, Phi Zeta Research Day, Colorado State

University 2005 Nomination, McKnight Land-Grant Professorship, University of Minnesota

December 15, 2013 5

2005 Who’s Who in American Women, Marquis’ Who’s Who 2006 Nomination, McKnight Land-Grant Professorship, University of Minnesota 2008 Mentor, Jeff Seaman, Mark S. Bloomberg Resident Research Award, Veterinary

Orthopedic Society 2008 Promotion to Associate Professor with full tenure 2009 MVMA Hero Award to patient, Batman Baker 2009 Mark of Excellence Award, College of Veterinary Medicine, University of

Minnesota 2010 Mentor, Katja Wucherer, Mark S. Bloomberg Resident Research Award,

Veterinary Orthopedic Society 2010 Mentor, Kristina Kiefer, Mark S. Bloomberg Resident Research Award,

Veterinary Orthopedic Society 2010 Resident Publication Award, mentor and co-author to Brian Rose, American

College of Veterinary Surgeons 2012 Mentor, Katja Wucherer, Mark S. Bloomberg Resident Research Award,

Veterinary Orthopedic Society 2012 Nomination, Emmy Awards, “Dakota’s Brain” 30-minute documentary on a dog

with a brain tumor treated in one of our clinical trials 2013 Mentor, Kristina Kiefer, Mark S. Bloomberg Resident Research Award,

Veterinary Orthopedic Society


Publications - Original Papers in Refereed Journals:

1. Kottas (Pluhar) GE, Mitchell JLA: Osmotically induced modifications of ornithinedecarboxylase in Physarum. FEBS Letters 102(2):265-268, 1979. PubMed PMID: 456605.

2. Gradin JL, Marta KM, Pluhar GE, Kaattari SL, Stephens JA, Sonn AE, Smith AW:Monoclonal antibodies against pili of serologically distinct Bacteroides nodosus. CanadianJournal of Veterinary Research 55(1):117-120, 1991. PubMed PMID: 1715810; PubMedCentral PMCID: PMC1263430.

3. Gradin JL, Stephens JA, Pluhar GE, Marta KM, Smith AW: Diversity of pilin ofserologically distinct Bacteroides nodosus. American Journal of Veterinary Research52(2):202-205, 1991. PubMed PMID: 1672804

4. Harari J, Tucker RL, Alexander JE, Pluhar L, Bagley RS: What’s your diagnosis? Septicarthritis of the coxofemoral joint in a dog. Journal of the American Veterinary MedicalAssociation 204(8):1159-1160, 1994. PubMed PMID: 8014083

December 15, 2013 6


5. Bagley RS, Pluhar GE, Alexander JE: Lateral intervertebral disk extrusion causing lamenessin a dog. Journal of the American Veterinary Medical Association 205(2):181-185, 1994.PubMed PMID: 7928570

6. Bagley RS, Baszler TV, Harrington ML, Pluhar GE, Moore MP, Keegan RD, Greene SA:Clinical effects of longitudinal division of the corpus callosum in normal dogs. VeterinarySurgery 24:122-127, 1995. PubMed PMID: 7778251

7. Pluhar GE, Memon ME, Wheaton LG: Granulosa cell tumor in an ovariohysterectomizeddog. Journal of the American Veterinary Medical Association 207(8):1063-1065, 1995.PubMed PMID: 7559047

8. Bagley RS, Harrington ML, Pluhar GE, Keegan RD, Greene SA, Moore MP, Gavin PR:Effect of craniectomy/durotomy alone and in combination with hyperventilation, diuretics,and corticosteroids on intracranial pressure in clinically normal dogs. American Journal ofVeterinary Research 57(1):116-119, 1996. PubMed PMID: 8720249

9. Tobias KT, Barbee D, Pluhar GE: Intraoperative use of subtraction angiography and anultrasonic aspirator to improve identification and isolation of an intrahepatic portosystemicshunt in a dog. Journal of the American Veterinary Medical Association 208(6):888-890,1996. PubMed PMID: 8617647

10. Pluhar GE, Bagley RS, Keegan RD, Baszler TV, Moore MP: The effect of acute, unilateraltransverse sinus occlusion on intracranial pressure in normal dogs. Veterinary Surgery25(6):480-486, 1996. PubMed PMID: 8923727

11. Pluhar GE, Tucker RL, Gavin PR, Bagley RS, Takeuchi, M: Cerebral sinus venography inthe dog: a new technique. Veterinary Radiology and Ultrasound 37(6):112-115, 1997.PubMed PMID: 9238778

12. Bagley RS, Harrington ML, Pluhar GE, Gavin PR, Moore MP: Acute, unilateral transversesinus occlusion during craniectomy in seven dogs with space-occupying intracranial disease.Veterinary Surgery 26(3):195-201, 1997. PubMed PMID: 9150557

13. Pluhar GE, Thabit G, Klohnen A, Vanderby R, Markel MD: In vitro effects ofholmium:YAG laser on caprine stifle retinacular restraints. Clinical Orthopaedics andRelated Research 356:170-179, 1998. PubMed PMID: 9917690

14. Robinson TM, Kruse-Elliot KT, Markel MD, Pluhar GE, Massa K, Bjorling DE: Acomparison of transdermal fentanyl versus epidural morphine for analgesia in dogsundergoing major orthopedic surgery. Journal of the American Animal Hospital Association35:95-100, 1999. PubMed PMID: 10102175

15. Pluhar GE, Heiner JP, Manley PA, Bogdanske JJ, Vanderby Jr R, Markel MD: Comparisonof three methods of gluteal tendon attachment to an allograft/endoprosthetic composite in acanine model. Journal of Orthopaedic Research 18:56-63, 2000. PubMed PMID: 10716279

16. Zabka AG, Pluhar GE, Manley PA, Hayashi K, Kalscheur VL, Seeherman HJ, Markel MD:Histomorphometric analysis of coupled allograft bone remodeling induced by rh BMP-2 in acanine femoral segmental defect model. Journal of Orthopaedic Research 19:318-327, 2001.PubMed PMID: 11347707

December 15, 2013 7


17. Pluhar GE, Manley PA, Heiner JP, Vanderby Jr R, Seeherman HJ, Markel MD: The effectof recombinant human bone morphogenetic protein-2 on femoral reconstruction with anintercalary allograft in a dog model. Journal of Orthopaedic Research 19:308-317, 2001.PubMed PMID: 11347706

18. Kudnig ST, Fitch RB, Pluhar GE, Salman MD: In vitro comparison of the holding power of1.2 mm, 1.5 mm, and 2.0 mm orthopedic screws placed in unicortical canine radial screwsites. Veterinary and Comparative Orthopaedics and Traumatology 15:78-84, 2002.

19. Fitch RB, Kerwin S, Hosgood G, Marquis RD, Pluhar GE, Kudnig ST: Treatment ofmechanically failed triple pelvic osteotomies in four dogs. Veterinary and ComparativeOrthopaedics and Traumatology 15:172-176, 2002.

20. Fitch RB, Kerwin S, Hosgood G, Rooney MB, Pluhar GE, Pelsue D: Radiographicevaluation and comparison of triple pelvic osteotomy with and without additional ventralplate stabilization. Veterinary and Comparative Orthopaedics and Traumatology 15:164171, 2002.

21. Frankel DJ, Pluhar GE, Skurla CP, Egger EL, James SP: Radiographic evaluation ofmechanically tested cemented total hip arthroplasty femoral components retrieved postmortem. Veterinary and Comparative Orthopaedics and Traumatology 17(4):216-224, 2004.

22. Skurla CP, Pluhar GE, Frankel DJ, Egger EL, James SP: Assessing the dog as a model forhuman total hip replacement: Analysis of 38 postmortem retrieved canine cemented femoralcomponents. Journal of Bone and Joint Surgery 87B(1):120-127, 2005. PubMed PMID:15686252

23. Liptak JM, Pluhar GE, Dernell WS, Withrow SJ: Limb-sparing surgery in a dog withosteosarcoma of the proximal femur. Veterinary Surgery 34:71-77, 2005. PubMed PMID:15720600

24. Nielsen C, Pluhar GE: Diagnosis and treatment of hind limb muscle strain injuries in 22dogs. Veterinary and Comparative Orthopaedics and Traumatology 18(4):247-253, 2005.PubMed PMID:16594394

25. Guedes AGP, Pluhar GE, Daubs BM, Rudé EP: Evaluation of pre-operative epiduralracemic ketamine for post-surgical analgesia in sheep. American Journal of VeterinaryResearch 67(2):222-229, 2006. PubMed PMID: 16454625

26. Reems MR, Pluhar GE, Wheeler DL: Ex vivo comparison of one vs. two screws in 8mminterlocking nails to stabilize canine distal femoral fractures. Veterinary Surgery 35(2):161167, 2006. PubMed PMID: 16472296

27. Nielsen C, Pluhar GE: Outcome following surgical repair of Achilles tendon rupture andcomparison between post-operative immobilization methods in dogs: 28 cases (1997-2004).Veterinary Comparative Orthopaedics and Traumatology 19(4):246-249, 2006. PubMedPMID: 17143398

28. Pluhar GE, Turner AS, Toth CA, Pierce A, Wheeler DL: Comparison of two biomaterialcarriers for osteogenic protein-1 (OP-1) in a model of ovine critical sized defects. Journal ofBone and Joint Surgery 88B(7):960-966, 2006. PubMed PMID: 16799005

December 15, 2013 8


29. Hammel SP, Pluhar GE, Novo RE, Bourgeault CA, Wallace LJ: Fatigue strength analysis ofplates used for radial fracture stabilization in small dogs. Veterinary Surgery 35:573-578,2006

30. Pluhar GE, Manley PA, Heiner JP, Vanderby Jr R, Markel MD: Gluteal muscle attachmentduring proximal femoral reconstruction in a canine model. Journal of Orthopaedic Research25(2):208-220, 2007. PubMed PMID: 17068814

31. Candolfi M, Kroeger K, Pluhar GE, Liu C, Barcia-Gonzalez C, Bergeron J, Puntel M,Curtin J, McNeil EA, Freese AB, Ohlfest JR, Moore P, Kuoy W, Lowenstein PR, CastroMG: Adenoviral mediated gene transfer into the dog brain. Neurosurgery 60(1):167-177,2007. PubMed PMID: 17228266; PubMed Central PMCID: PMC2095776

32. Candolfi M, Pluhar GE, Kroeger K, Puntel M, Curtin J, Barcia C, Muhammad AKMG,Xiong W, Liu C, Mondkar S, Kuoy W, Kang T, McNeil EA, Freese AB, Moore P, Palmer D,Ng P, Young JD, Lowenstein PR, Castro MG: Optimization of adenoviral vector-mediatedtransgene expression in the canine brain in vivo, and in canine glioma cells in vitro. Neurooncology 9(3):245-258, 2007. PubMed PMID: 17522335; PubMed Central PMCID:PMC1907414

33. Santoni BG, Pluhar GE, Motta T, Wheeler DL: Hollow calcium phosphate microcarriers forbone regeneration: In vitro osteoproduction and ex vivo biomechanical assessment. Bio-Medical Materials and Engineering 17(5):277-289, 2007. PubMed PMID:17851170

34. Oh S, Pluhar GE, McNiel EA, Kroeger KM, Castro MG, Lowenstein PR, Freese AB,Ohlfest JR: Efficacy of nonviral gene transfer into the canine brain. Journal of Neurosurgery107(1):136-144, 2007. PubMed PMID: 17639883; PubMed Central PMCID: PMC2384235

35. Candolfi M, Curtin JF, Nichols WS, Muhammad AKMG, King GD, Pluhar GE, McNeilEA, Ohlfest JR, Freese AB, Moore PF, Lerner J, Lowenstein PR, Castro MG: Intracranialglioblastoma models in preclinical neuro-oncology: neuropathological characterization andtumor progression. Journal of Neurooncology 85(2):133-148, 2007. PubMed PMID:17874037; PubMed Central PMCID: PMC2384236

36. Hansen RA, Harris MA, Pluhar GE, Motta T, Brevard S, Ogilvie GK, Fettman MJ, AllenKGD: Fish oil decreases matrix metalloproteinases in knee synovia of dogs withinflammatory joint disease. Journal of Nutritional Biochemistry 19(2):101-108, 2008

37. Bevan J, Lulich J, Osborne C, Pluhar GE: Laser lithotripsy and cystotomy are equallyeffective for management of canine urocystoliths and urethroliths. Journal of VeterinaryInternal Medicine 22(3):732-734, 2008

38. Seaman JA, Pluhar GE, Rose ND, Weinstein JI, Guo H, Anderson KL: Evaluation ofscintigraphy to assess incorporation of intercalary cortical bone grafts in sheep. AmericanJournal of Veterinary Research 70(9):1079-1086, 2009. PubMed PMID: 19719422

December 15, 2013 9


39. Rose BW, Pluhar GE, Novo RE, Lunos S: Biomechanical analysis of stacked platingtechniques to stabilize distal radial fractures in small dogs. Veterinary Surgery 38(8):954960, 2009. PubMed PMID: 20017853

40. Pluhar GE, Grogan PG, Seiler C, Goulart M, SantaCruz KS, Carlson C, Chen W, Olin MR,Lowenstein PR, Castro MG, Haines SJ, Ohlfest JR. Anti-tumor immune response correlateswith neurological symptoms in a dog with spontaneous astrocytoma treated by gene andvaccine therapy. Vaccine 28(19):3371-8, 2010. PubMed PMID: 20197146; PubMed CentralPMCID: PMC2854671

41. Xiong W, Candolfi M, Liu C, Puntel M, Moore PF, Avalos J, Young JD, Khan D, DonelsonR, Pluhar GE, Ohlfest JR, Wawrowsky K, Lowenstein PR, and Castro MG: Human Flt3Linduces proliferation and differentiation of canine dendritic cells: implications for a dogglioma clinical trial. PLoS One 5(6):e11074, 2010. PubMed PMID: 20552015; PubMedCentral PMCID: PMC2884015

42. Pinel CB, Pluhar GE: Clinical application of recombinant human bone morphogeneticprotein in cats and dogs: a retrospective review of 13 cases. Canadian Veterinary Journal53(7):767-774, 2012. PubMed PMID: 23277644; PubMed Central PMCID: PMC3377460

43. Goulart M, Pluhar GE, Ohlfest JR: Identification of myeloid derived suppressor cells indogs with naturally occurring cancer. PLoS ONE 7(3):e33274, 2012. PubMed PMID:22428007; PubMed Central PMCID: PMC3302813

44. Andersen BM, Pluhar GE, Seiler CE, Goulart MR, SantaCruz KS, Schutten MM, Meints,JP, O’Sullivan MG, Bentley RT, Packer RA, Thomovsky SA, Chen AV, Faissler D, HuntMA, Ohlfest JR: Vaccination for invasive canine meningioma induces in situ production ofantibodies capable of antibody-dependent cell-mediated cytotoxicity. Cancer Research,73(10):2987-97, 2013. PubMed PMID: 23471847; PubMed Central PMCID: PMC3655124

45. Bentley RT, Ober CP, Anderson KL, Feeney DA, Naughton JF, Ohlfest JR, O’Sullivan MG,Miller MA, Constable PD, Pluhar GE: Canine intra-axial primary brain tumors: relationshipbetween magnetic resonance imaging criteria and tumor type and grade. The VeterinaryJournal, 198(2):463-71, 2013. PubMed PMID: 24051197; PubMed Central PMCID:PMC3868339

46. Murphy KA, Pluhar GE, Erickson JR, Johnson CS, Seiler C, Bedi J, Hu P, Epstein AL,Ohlfest JR. CD8+ T cell independent tumor regression induced by Fc-OX40L andtherapeutic vaccination in a mouse model of glioma. The Journal of Immunology, 192:224233, 2014. PubMed PMID: 24293627; PubMed Central PMCID: PMC4068509

47. Kiefer K, Pluhar GE, Conzemius MG, O’Brien TD. The influence of culture medium typeon cellular phenotype of canine adipose derived stem cells. Open Journal of RegenerativeMedicine, 3:28-37, 2014.

December 15, 2013 10


48. Anderson BM, Goulart MR, Olin MR, Pluhar GE. Detection of tumor cell surface-reactiveantibodies. Bio-Protocol, 4(9): epub, 2014.

49. Olin MR, Pluhar GE, Andersen BM, Shaver R, Waldron NN, Moertel CL. Victory anddefeat in the induction of a therapeutic response through vaccine therapy for human andcanine brain tumors: A review of the state of the art (invited review). Critical Reviews inImmunology, 34(5):399-432, 2014. PubMed PMID: 25404047; PubMed Central PMCID:PMC4485925

50. Kiefer KM, O’Brien T, Pluhar GE, Conzemius MG. Canine adipose derived stromal cellviability following exposure to synovial fluid from osteoarthritic joints. Vet Record Open,2(1):e000063, 2015. PubMed PMID: 26392889; PubMed Central PMCID: PMC4567176

51. Brock GR, Chen J, Ingraffea AR, MacLeay J, Pluhar GE, Boskey AL, van der MeulenMCH. The effect of osteoporosis treatments on fatigue properties of cortical bone tissue.Bone Reports, 2:8-13, 2015. PubMed PMID: 25642445; PubMed Central PMCID:PMC4306187

52. Pluhar GE, Pennell CA, Olin MR. CD8+ T cell-independent immune-mediated mechanismsof anti-tumor activity (invited review). Critical Reviews in Immunology, 35(2)153-172, 2015.PubMed PMID: 26351148; PubMed Central PMCID: PMC4870933

53. Thomson CB, Haynes K, Pluhar GE. Comparison of visual metric and planimetry methodsfor brain tumor measurement in dogs. American Journal of Veterinary Research, 77(5):4717, 2016. PubMed PMID: 27111014

54. LeBlanc AK, Mazcko C, Brown DE, Koehler JW, Miller AD, Miller CR, Bentley RT, PackerRA, Breen M, Boudreau CE, Levine JM, Simpson RM, Halsey C, Kisseberth W, RossmeislJH Jr, Dickinson PJ, Fan TM, Corps K, Aldape K, Puduvalli V, Pluhar GE, Gilbert MR.Creation of an NCI comparative brain tumor consortium: informing the translation of newknowledge from canine to human brain tumor patients. Neuro Oncol, pii: now051, 2016.PubMed PMID: 27179361.

55. MacLellan JD, Arnold SA, Dave AC, Hunt MA, Pluhar GE. Correlation of MRI-basedpreoperative tumor volume with survival in dogs with primary intracranial glioma: 47 cases(2008-2015). J Am Vet Med Assoc, in press.

56. Kohler RJ, Arnold SA, Thomson C, Hunt MA, Pluhar GE. Short-term complications andrisk factors in dogs undergoing craniotomy for solitary intracranial masses: 160 cases (20092015). J Am Vet Med Assoc, in press.

57. Luangphakdy V, Pluhar GE, Piuzzi NS, D’Alleyrand J-C, Carlson CS, Bechtold JE,Forsberg J, Muschler GF. The Masquelet Induced Membrane Technique: OptimizingSurgical Technique and Spacer Design. Comp Ortho Rel Res, in press.



Manuscripts Submitted or in Preparation:

1. Chen JT, Baker SP, Pluhar GE, Boskey AL, van der Meulen MCH. PTH treatment alteredcortical tissue-level properties but not whole bone bending strength. OsteoporosisInternational, in review.

2. Hubbard M, Arnold SA, Bin Zahid A, McPheeters M, Hunt MA, Pluhar GE. NaturallyOccurring Canine Glioma as a Model for Novel Therapeutics. Journal of Neuo-Oncology, inreview.

3. Pluhar GE, Zhang R, Conzemius MG, Ngo C, Kulesha G, Hawkins M, Murray N, Zitelli J.Effect of Surface Treatment on Bone In-growth into Porous Titanium Using a Canine THAModel. Journal of Arthroplasty, in review.

4. Pluhar GE, Anderson BM, Hunt MA, Seiler C, Ohlfest JR. Surgery and immunotherapy totreat dogs with spontaneous intracranial meningioma. Submitted Veterinary Surgery, inreview.

5. Pluhar GE, Battjes E, Nielsen C. Treatment of canine elbow osteoarthritic pain withintraarticular hyaluronic acid. Resubmitted Canadian Veterinary Journal, in review.

6. Pluhar GE, Schutten M, Armien A. Diagnosis of a central rhabdoid meninigioma in a dog.Submitted Veterinary Pathology, in review.

7. Assad M, Chagnon M, Beaudry D, Wilson J, Pluhar GE, Lussier B, Cantwell M. Safety andefficacy of PEEK intramedullary nail fixation system using an ovine tibial fracture repairmodel. In preparation.

8. Pluhar GE, Bechtold J, Nicholson A, Luangphakdy V, Boehm C, Carlson C, Muschler G.Development and characterization of a chronic tibial defect model in goats. In preparation.

9. Pluhar GE, Hunt MA. Surgical debulking of central gliomas in dogs. In preparation.

10. Kiefer K, Pluhar GE, Conzemius MG. Autologous and allogeneic stromal cells as adjuvanttherapy for osteoarthritis caused by spontaneous fragmented coronoid process in dogs. Inpreparation.

Books and Book Chapters:

1. Egger E, Pluhar GE. 2010. Enhancement of fracture healing. In: Bojrab MJ & Monnet E,editors. Disease Mechanisms in Small Animal Surgery 3rd edition. Philadelphia:Lea &Febiger

2. Pluhar GE. 2016. Thermal Pain. In: Griffon D & Hamaide A, editors. Complications inSmall Animal Surgery. Ames:Wiley-Blackwell



3. Pluhar GE. 2016. Fracture Associated Sarcoma. In: Griffon D & Hamaide A, editors.Complications in Small Animal Surgery. Ames:Wiley-Blackwell

4. Pluhar GE, Zachos T. Animals Models of Bone Engineering. In: Animal Models for the isease 2nd edition. Academic Press/Elsevier. In preparation Study of Human D

Published Abstracts:

1. Kottas (Pluhar) GE, Mitchell JLA: Ornithine decarboxylase form interconversion.Proceedings of the International Congress of Biochemistry, 1979.

2. Sande RS, Alexander JE, Pluhar GE, Tucker RL: Achondrogenesis in an Akita: Aspontaneous mutation. Proceedings of the International Veterinary Radiology Society, 1994.

3. Pluhar GE, Bagley RS, Keegan RD, Moore MP: Effects of acute, unilateral transversevenous sinus occlusion on intracranial pressure in normal dogs. Veterinary Surgery23(5):425, 1994.

4. Bagley RS, Harrington ML, Pluhar GE, Keegan RD, et al: The effect ofcraniectomy/durotomy, alone or in combination with hyperventilation, diuretics andcorticosteroids, on intracranial pressure in normal dogs. Journal of Veterinary InternalMedicine 9:191, 1995.

5. Pluhar GE, Thabit G, Klohnen A, Warner C, Obrzut SL, Vanderby R, Markel MD: Lateralrelease and medial joint capsular modification of the patellofemoral joint using theHolmium:YAG laser. Proceedings of the Orthopaedic Research Society, 1997.

6. Pluhar GE, Heiner JP, Manley PA, Bogdanske JJ, Markel MD: Comparison of threemethods of gluteal tendon attachment to an allograft/endoprosthetic composite in total hiparthroplasty: Nine month radiographic and force plate data. Veterinary Surgery 26(5):424,1997.

7. Pluhar GE, Heiner JP, Manley PA, Bogdanske JJ, Markel MD: Comparison of threemethods of gluteal tendon attachment to an allograft/endoprosthetic composite of theproximal femur in an in vivo canine model. Proceedings of the Connective Tissue OncologySociety, 1997.

8. Pluhar GE, Manley PA, Heiner JP, Bogdanske JJ, Vanderby Jr R, Markel MD: Comparisonof three methods of tendon attachment to an allograft/endoprosthetic composite of theproximal femur in an in vivo canine model. Proceedings of the Orthopedic Research Society,1998.

9. Pluhar GE, Manley PA, Bogdanske JJ, Heiner JP, Vanderby Jr R, Markel MD: Comparisonof three methods of gluteal tendon attachment to an allograft/endoprosthetic compositeduring total hip replacement. Veterinary Surgery 27(5):528, 1998.

10. Pluhar GE, Manley PA, Heiner JP, Bogdanske JJ, Day DK, Hayashi K, Devitt JJ, VanderbyJr R, Seeherman HJ, Markel MD. The effect of rhBMP-2 on femoral reconstructions withintercalary allografts. Proceedings of the Orthopedic Research Society, 1999.



11. Pluhar GE, Manley PA, Heiner JP, Bogdanske JJ, Vanderby Jr R, Markel MD. Hipreconstruction with an allograft/endoprosthetic composite in dogs: Long term results.Proceedings of the Orthopedic Research Society, 1999.

12. Pluhar GE, Heiner JP, Manley PA, Vanderby Jr R, Seeherman HJ, Markel MD. The effectof rhBMP-2 on femoral reconstructions with intercalary allografts. Proceedings of theInternational Society of Limb Salvage, 1999.

13. Heiner JP, Pluhar GE, Manley PA, Bogdanske JJ, Day DK, Hayashi K, Devitt JJ,Seeherman HJ, Vanderby Jr. R, Markel MD. . The effect of rhBMP-2 on femoralreconstructions with intercalary allografts. Proceedings of the Musculoskeletal TumorSociety, 1999.

14. Zabka AG, Pluhar GE, Manley PA, Hayashi K, Kalscheur VL, Seeherman HJ, Markel MD.Coupled allograft bone remodeling induced by bone morphogenetic protein-2 in a caninefemoral segmental defect model. Veterinary Surgery 28(5):414, 1999.

15. Pluhar GE, Manley PA, Heiner JP, Bogdanske JJ, Day DK, Hayashi K, Devitt JJ,Seeherman HJ, Vanderby Jr. R, Markel MD. Augmentation of femoral reconstructions withintercalary allografts using bone morphogenetic protein. Veterinary Surgery 28(5):402, 1999.

16. Zabka AG, Pluhar GE, Manley PA, Hayashi K, Edwards III R, Heiner JP, Kalscheur VL,Seeherman HJ, Markel MD. Recombinant human bone morphogenetic protein-2 inducescoupled allograft bone remodeling in a femoral segmental defect using a canine model.Proceedings of the Orthopedic Research Society, 2000.

17. James SP, Skurla C, Wheeler DL, Pluhar GE. Long-term wear and mechanical stabilityanalysis of 38 post-mortem retrieved canine total hip replacements. Proceedings of theOrthopaedic Research Society, 2002.

18. Rooney MB, Kudnig ST, Frankel DJ, Reems MR, Fitch RB, Pluhar GE. Determination ofthe association between tibial plateau angle and cranial cruciate ligament rupture in the dog.Proceedings of the Veterinary Orthopedic Society, 2002.

19. Wheeler DL, Liu C, James SP, Gearen P, Myers S, Pluhar GE. Antimicrobial efficacy ofeluted tobramycin and vancomycin from bone cement: Effects of antibiotic particle size.Proceedings of the Society for Biomaterials, 2002.

20. Wheeler DL, Liu C, James SP, Gearen P, Myers S, Pluhar GE. Effects of antibiotic particlesize on elution characteristics from bone cement. Proceedings of the Society forBiomaterials, 2002.

21. Skurla CP, James SP, Wheeler DL, Pluhar GE. A novel method for assessing mechanicalstability of acetabular components: Results from 38 postmortem retrieved canine implants.Proceedings of the Orthopaedic Research Society, 2003.

22. Santoni BG, Pluhar GE, Koenig AL, Motta T, Wheeler DL. Calcium phosphatemicrocarriers for bone regeneration: In vitro osteoproduction and ex vivo biomechanicalassessment. Proceedings of the Orthopaedic Research Society, 2003.

23. Line BG, Pluhar GE, Turner AS, Toth CA, Wheeler DL. Structural and material properties



of OP-1 healed tibiae. Proceeding of the Orthopaedic Research Society, 2003.

24. Pluhar GE, Turner AS, Toth CA, Friedlander G, Wheeler DL. Comparison of OP-1 carriersfor healing of tibial diaphyseal defects in an ovine model. Proceedings of the OrthopaedicResearch Society, 2003.

25. Read JL, Berrey BH, Scarborough MT, Enneking W, Pluhar GE, Wheeler DL. Materialproperties of retrieved massive allograft cortical bone. Proceedings of the OrthopaedicResearch Society, 2003.

26. Skurla CP, James SP, Pluhar GE. Long-term wear damage analysis of 38 postmortemretrieved canine total hip replacements. Proceedings of the Orthopaedic Research Society,2003.

27. Wheeler DL, Pluhar GE, Turner AS, Toth CA, Friedlander G. Healing of large segmentaltibial defects with OP-1 putty in an ovine model. Proceedings of the American Academy ofOrthopaedic Surgeons, 2003.

28. Reems MR, Pluhar GE, Landmann B, Wheeler DW. Ex vivo comparison of the model 11versus model 22 interlocking nail systems to stabilize distal canine femoral fractures.Proceedings of the Veterinary Orthopedic Society, 2003.

29. Reems MR, Pluhar GE, Landmann B, Wheeler DW. Ex vivo comparison of one versus twodistal screws in 8mm interlocking nails to stabilize mid-diaphyseal canine tibial fractures.Proceedings of the Veterinary Orthopedic Society, 2003.

30. Frankel DJ, Skurla C, Egger EL, Pluhar GE. Biomechanical and radiographic evaluation oftotal hip arthroplasty femoral components retrieved post-mortem. Proceedings of theVeterinary Orthopedic Society, 2003.

31. Reems MR, Pluhar GE, Wheeler DW. Ex vivo comparison of one versus two distal screwsin 8mm interlocking nails to stabilize mid-diaphyseal canine tibial fractures. VeterinarySurgery 32(5):494, 2003.

32. Reems MR, Pluhar GE, Wheeler DW. Ex vivo comparison of the model 11 versus model 22interlocking nail systems to stabilize distal canine femoral fractures. Veterinary Surgery32(5):494, 2003.

33. Frankel DJ, Skurla C, Egger EL, Pluhar GE. Mechanical and radiographic evaluation oftotal hip arthroplasty femoral components retrieved post-mortem. Veterinary Surgery,32(5):486, 2003.

34. Wheeler DW, Jackinsky SW, Mohr KE, Pluhar GE, Turner AS, Toth CA. Osteogenicprotein-1 (OP-1/BMP-7) enhanced cement as an OP-1 carrier for healing of tibial diaphysealdefects in an ovine model. Proceedings of the Orthopaedic Research Society, 2004.

35. Wheeler DW, Jackinsky SW, Mohr KE, Eschbach E, Pluhar GE, Turner AS, Toth CA. TCPputty as an osteogenic protein-1 carrier for healing of tibial diaphyseal defects in an ovinemodel. Proceedings of the Orthopaedic Research Society, 2004.

36. Wheeler DW, Jackinsky SW, Mohr KE, Eschbach E, Pluhar GE, Turner AS, Toth CA.Tricalcium phosphate putty as an osteogenic protein-1 (OP-1/BMP-7) carrier for healing of



tibial diaphyseal defects in an ovine model. Proceedings of the World Congress of Biomaterials, 2004.

37. Skurla CP, Wheeler DJ, Pluhar GE, James SP. Post-Mortem retrieval of 38 canine THRs

with implant durations up to 11.7 years: The dog a s a model for human THR. Transactions of the 7th World Biomaterials Congress, 2004: 548.

38. Pluhar GE. Study of retrieved canine cemented total hip implants. Proceedings of the

Annual Symposium of the American College of Veterinary Surgeons, 2004. pp. 285-288. 39. Pluhar GE. Orthopedic applications of mesenchymal stem cells. Proceedings of the Annual

Symposium of the American College of Veterinary Surgeons, 2004. pp. 326-328. 40. Pluhar GE. Delivery of osteogenic protein-1 in tricalcium phosphate cement: An ovine tibial

ostectomy study. Proceedings of the 1st Annual Current Topics in Orthopaedic ResearchSeminar, 2004.

41. Pluhar GE. Interlocking nailing for small animal fracture fixation. Proceedings of the 108th

Annual Meeting of the Minnesota Veterinary Medical Association, 2005. 42. Nielsen C, Pluhar GE. Hip adductor muscle injuries in 22 dogs. Proceedings of the

Veterinary Orthopedic Society, 2005. 43. Pluhar GE, Liptak JM, Manley PA, Heiner JP, Markel MD. Treatment of proximal femoral

osteosarcoma with allograft-prosthetic composites. Proceedings of the Veterinary Orthopedic Society, 2005.

44. Pluhar GE. Basic nomenclature of external skeletal fixation and biomechanics. Proceedings

of 142nd Annual Convention of the American Veterinary Medical Association and 28th WorldVeterinary Congress, 2005.

45. Pluhar GE. Diagnosis and treatment of iliopsoas injuries. Proceedings of the Annual

Symposium of the American College of Veterinary Surgeons, 2005. pp. 343-345. 46. Pluhar GE. Biostimulation of fracture healing. Proceedings of the Annual Symposium of the

American College of Veterinary Surgeons, 2005. pp. 266-269. 47. Pluhar GE. Importance of periosteal removal on critical size defect healing. Proceedings of

the 2nd Annual Current Topics in Orthopaedic Research Seminar, 2005. 48. Nielsen C, Pluhar GE. Outcome following surgical repair of Achilles tendon rupture: 30

cases in 28 dogs (1997-2004). Veterinary Surgery 34(4):E18, 2005. 49. Pluhar GE. Biomechanics of interlocking nails. Proceedings of the 109th Annual Meeting of

the Minnesota Veterinary Medical Association, 2006. 50. Pluhar GE. Results and complications of ILN use. Proceedings of the 109th Annual Meeting

of the Minnesota Veterinary Medical Association, 2006.



51. Pluhar GE, Wheeler DL, Toth CA. Importance of periosteum removal on critical sizeddefect healing. Proceedings of the Orthopaedic Research Society, 2006.

52. Pluhar GE. Clinical use of osteogenic protein-1 in veterinary delayed/non union fractures.

Veterinary and Comparative Orthopaedics and Traumatology 19(3):A27-28, 2006. 53. Candolfi M, Curtin J, King GD, Pluhar GE, McNiel E, Ohlfest JR, Freese AB, Moore PF,

Nichols SW, Lowenstein PR, Castro MG. Glioblastoma multiforme (GBM): a comparative histological analysis of gliomas in mice, rats, dogs and humans. Abstracts of the AmericanAssociation for Cancer Research Meeting, Apr 2006: 642.

54. Pluhar GE. Importance of periosteal removal on critical size defect healing. Veterinary and

Comparative Orthopaedics and Traumatology 19(3):A28, 2006. 55. Pluhar GE. Importance of periosteal removal on critical size defect healing. Veterinary

Surgery 35(6):E21, 2006. 56. Pluhar GE. Clinical use of osteogenic protein-1 in veterinary delayed/non union fractures.

Veterinary Surgery 35(6):E21, 2006. 57. Robinson DA, Pluhar GE, Hart A, Evans R, Conzemius MG. Force platform gait analysis to

characterize lameness associated with sodium urate induced synovitis. Proceedings of the 34thAnnual Meeting of the Veterinary Orthopedic Society, 2007.

58. Candolfi M, Curtin J, Nichols W, Muhammad A, Puntel M, King G, Xiong W, Kroeger K,

Barcia C, Liu C, Mondkar S, Pluhar G, McNiel E, Ohlfest J, Freese A, Moore P, Palmer D, Ng P, Young J, Lowenstein P, Castro M. The canine spontaneous glioblastoma as preclinical large animal model for brain cancer gene therapy. Abstracts of the American Association for Cancer Research Meeting, Apr 2007: 4135.

59. Pluhar GE, Seaman JA, Anderson KL. Nuclear scintigraphy is not a sensitive measure of

bone graft incorporation. Proceedings of the 34thAnnual Meeting of the Veterinary Orthopedic Society, 2008.

60. Pluhar GE, Tchernatynskaia AV, Olin MR, Long C, Grogan PT, Ohlfest JR. Feasibility

studies to target brain tumor initiating cells using immunotherapy in dogs with spontaneous glioma. Abstracts of the Society for Neuro-Oncology Meeting, Nov 2008: 178.

61. Ngo C, Zhang R, Kulesha G, Zitelli J, Hawkins M, Pluhar GE. Effect of Surface Treatment

on Bone In-growth into Porous Titanium Using a Canine THA Model. Proceedings of the Orthopaedic Research Society, 2009.

62. GE Pluhar, Zhang R, Conzemius MG, Ngo C, Kulesha G, Hawkins M, Murray N, Zitelli J.

Tritanium™ induces rapid bone ingrowth in a canine hip a rthroplasty model. Proceedings of the Orthopaedic Research Society, 2009.

63. Pluhar GE, Battjes E, Nielsen C. Intraarticular hyaluronic acid increases weight bearing in



dogs with elbow OA. Proceedings of the 35thAnnual Meeting of the Veterinary Orthopedic Society, 2009.

64. Rose BW, Pluhar GE, Novo RE, Lunos S. Fatigue Analysis For Stack Plating. Proceedings

of the Symposium of the American College of Veterinary Surgeons, 2009. 65. Pluhar GE, Chen W, Grogan PT, Seiler C, Bedi JJ, Olin M, Carlson CS, SantaCruz KA,

Castro MG, Lowenstein P, Haines S, Hunt M, Ohlfest JR. Tumor responses in dogs withspontaneous astrocytoma and papillary meningioma treated by immunotherapy. Abstracts of the Society for Neuro-Oncology Meeting, 2009.

66. Kiefer K, Conzemius M, Pluhar GE, O’Brien T, Clarkson C. Expression of inflammatory

mediators in canine adipose and bone marrow derived stem cell populations as a function of cell culture. Proceedings of the 37thAnnual Meeting of the Veterinary Orthopedic Society,2010.

67. Pluhar GE. Successful submissions: mastering the research grant proposal process.

Proceedings of the Symposium of the American College of Veterinary Surgeons, 2010. 68. Pluhar GE. Acetabular fractures. Proceedings of the 3rd Annual Meeting of the World

Veterinary Orthopedic Congress, 2010. 69. Pluhar GE. Ulnar osteotomy. Proceedings of the 3rd Annual Meeting of the World

Veterinary Orthopedic Congress, 2010. 70. Anderson BM, Pluhar GE, Hunt MA, Gallardo JL, Seiler, C, Ohlfest JR. I mmunotherapy of

spontaneous canine meningioma: A preclinical model. Abstracts of the Society for Neuro-Oncology Meeting, Nov 2010.

71. Olin MR, Anderson BM, Pluhar GE, Grogan PT, Hunt MA, Popescu FE, Xiong Z L, Seiler

C, Forster CL, SantaCruz KS, Chen W, Blazar BR, Ohlfest JR. Glioma cells cultured in 5% oxygen enhance the efficacy of tumor cell vaccination in a toll-like receptor 2-dependent manner. Abstracts of the Society for Neuro-Oncology Meeting, Nov 2010.

72. Pluhar GE. Professional Development Series: Launching your Career. Nailing the

Interview. Proceedings of the Orthopaedic Research Society, January 2011. 73. Pluhar GE. Fracture session: Introductory Case Presentation. Proceedings of the 38thAnnual

Meeting of the Veterinary Orthopedic Society, March 2011. 74. Pluhar GE. Clinical Trials for Dogs with Glial Tumors: Beyond Batman. Proceedings of the

Neurology Specialty Symposium of the American College of Veterinary Internal Medicine,June 2011.



75. Pan H, Luangphakdy V, Shinohara K, Boehm C, Wenke J, Pluhar GE, Bechtold J, Muschler G. Bone regeneration strategies in a chronic caprine tibial defect model. Proceedings of the Advanced Technology Applications for Combat Casualty Care Meeting, August 2011.

76. Hunt MA, Pluhar GE, Andersen BM, Gallardo JL, Seiler CE, Ohlfest JR. Surgery Plus

Immunotherapy is Superior to Surgery Alone for Control of Spontaneous Canine Meningiomas. Proceedings of the Annual Meeting of the Congress of Neurological Surgeons,October 2011.

77. Pluhar GE. Technique of Interlocking Nail Fixation. Proceedings of the Symposium of the

American College of Veterinary Surgeons, November 2011. 78. Pluhar GE. Interlocking Nail Instrumentation. Proceedings of the Symposium of the

American College of Veterinary Surgeons, November 2011. 79. Hunt MA, Pluhar GE, Andersen BM, Gallardo JL, Seiler CE, SantaCruz KS, Ohlfest JR.

Surgery and Immunotherapy I mproves Survival over Surgery Alone for Canine Meningiomas. Abstracts of the Society for Neuro-Oncology Meeting, Nov 2011.

80. Pluhar GE, Muschler G, Pan H, Luangphakdy V, Shinohara K, Boehm C, Wenke J,

Bechtold J, Nicholson A. Development of a chronic caprine tibial defect model. Proceedings of the Armed Forces Institute of Regenerative Medicine All Hands Meeting, February 2012.

81. Kiefer K, O’Brien T, Pluhar GE, Conzemius MG. The influence of culture medium

conditions on canine adipose derived stem cells. Proceedings of the 39thAnnual Meeting of the Veterinary Orthopedic Society, March 2012.

82. Pluhar GE. Canines curing cancer: Transforming br ain tumor therapy. Proceedings of the 1st

Annual Neuro-Oncology Symposium, May 2012. 83. Pluhar GE. Technique of Interlocking Nail Fixation. Proceedings of the Symposium of the

American College of Veterinary Surgeons, October 2012. 84. Pluhar GE. Interlocking Nail Instrumentation. Proceedings of the Symposium of the

American College of Veterinary Surgeons, October 2012. 85. Andersen BM, Pluhar GE, Seiler CE, Xiong Z , Goulart MR, Zhang Z , O’Sullivan MG,

Hunt MA, Schiaffo CE, Ferguson DE, Ohlfest JR. Preclinical testing of three toll-like receptor ligands in vaccination therapy for invasive canine meningioma. Proceedings of the American Association of Cancer Research Tumor Immunology Conference, December 2012.

86. Goulart MR, Pluhar GE, Andersen BM, Seiler CE, Hunt MA, Zhang Z M, O'Sullivan MG,

Johnson C, Ohlfest JR. Immunotherapy as treatment for dogs with glioma. Proceedings of the American Association of Cancer Research Tumor Immunology Conference, December 2012.



87. Andersen BM, Pluhar GE, Seiler CE, Xiong Z , Goulart MR, O’Sullivan MG, Hunt MA,Schiaffo CE, Ferguson DM, Ohlfest JR. Preclinical testing of three immune adjuvants in vaccination therapy for invasive canine meningioma. Proceedings of the AACR Special Conference on Tumor Immunology: December, 2012.

88. Pluhar GE, Nicholson A, Muschler G, Luangphakdy V, Bechtold J, Boehm C, Carlson C,

Pan H, Shinohara K, Wenke J. Development of a chronic caprine tibial defect model. Proceedings of the Orthopaedic Research Society, January 2013.

89. Pluhar GE. Canines Curing Cancer: Transforming B rain Tumor Therapy. Skippy Frank

Comparative Translational Medicine Conference, February 2013. 90. Kiefer K, Wucherer KL, Pluhar GE, Conzemius MG. Autologous and allogeneic stem cells

as adjuvant therapy for osteoarthritis caused by spontaneous fragmented coronoid process indogs. Proceedings of the 40thAnnual Meeting of the Veterinary Orthopedic Society, March 2013.

91. Kiefer K, Conzemius MG, Pluhar GE. Canine adipose derived stem cell viability following

exposure to synovial fluid from osteoarthritic joints. Proceedings of the 40th Annual Meetingof the Veterinary Orthopedic Society, March 2013.

92. Pluhar GE. Autologous vaccine therapy to control invasive canine meningioma.

Proceedings of the AANS/CNS 10th Biennial Satellite Tumor Symposium, April 2013. 93. Pluhar GE. Canine Glioma Clinical Trials Experience at the University of Minnesota.

Proceedings 2nd Bi-Annual Veterinary Neurosurgical Society Symposium, Portland, OR.August 2013.

94. Pluhar GE. Surgery/immunotherapy improves survival over surgery alone to treat canine

meningioma. Proceedings 2nd Bi-Annual Veterinary Neurosurgical Society Symposium,Portland, OR. August 2013.

95. Goulart MR, Andersen BM, Seiler CE, Hunt MA, Zhang Z , O'Sullivan MG, Johnson C,

Ohlfest JR, Olin M, Pluhar GE. Vaccination with autologous glioma lysate induces tumor-reactive IgG antibody response and i ncreases survival in dogs with glioma. Proceedings of the 15th International Congress of Immunology. Milan, Italy, August 2013.

96. Pluhar GE. Characterization of a chronic tibial defect model in goats. Proceedings Military

Health System Research Symposium, F t. Lauderdale, FL. August 2013. 97. Pluhar GE. Vaccine immunotherapy for canine meningioma: Clinical and translational

aspects. Proceedings 2nd Neuro-Oncology Symposium, Minneapolis, MN, September 2013. 98. Goulart MR, Andersen BM, Seiler CE, Hunt MA, Zhang Z , O'Sullivan MG, Johnson C,

Ohlfest JR, Olin M, Pluhar GE. Vaccination with autologous glioma lysate induces tumor-reactive IgG antibody response and increases survival in dogs with glioma. Proceedings 2nd



Neuro-Oncology Symposium, Minneapolis, MN, September 2013. 99. Pluhar GE. Immunotherapy of canine meningioma. Proceedings of the Symposium of the

American College of Veterinary Surgeons, San Antonio, TX. October 2013. 100. Pluhar GE. Surgery and immune/gene therapy for canine gliomas. Proceedings of the

Symposium of the American College of Veterinary Surgeons, San Antonio, TX, October 2013.

101. Pluhar GE. Imaging of brain tumors. Proceedings of the Symposium of the American

College of Veterinary Surgeons, San Antonio, TX, October 2013. 102. Pluhar GE, Nicholson A, Muschler G, Luangphakdy V, Bechtold J, Boehm C, Carlson C,

Pan H. Development of a Caprine Chronic Tibial Defect Model. Proceedings of the 41st Annual Meeting of the Orthopedic Research Society, March 2014.

103. Boehm C, Zaveri P, Luangphakdy L , Pluhar GE, Carlson C, Muschler GF. Cellular and

Histological Analyses of Induced Membrane Produced in a Caprine Chronic Tibial Defect Model. Proceedings of the 41st Annual Meeting of the Orthopedic Research Society, March 2014.

104. Boehm C, Luangphakdy V, Pan H, Shinohara K, MD, Nicholson A, Bechtold J, Carlson C,

Pluhar GE, Muschler G. Comparison of Bone Marrow Aspiration Site Options in the Spanish Boer Goat – P art of Development of a Rigorous Caprine Tibial Defect Model. Proceedings of the 41st Annual Meeting of the Orthopedic Research Society, March 2014.

105. Pluhar GE, Nicholson A, Muschler G, Luangphakdy V, Bechtold J, Boehm C, Carlson C,

Pan H. Effect of Grafting Materials on Bone Healing in a Chronic Caprine Tibial Defect Model. Proceedings of the 2014 Military Health System Research Symposium, August 2014.

106. Pluhar GE. Nicholson A, Luangphakdy V, Bechtold J, Carlson C, Boehm C, Muschler G.

Large animal model of a critical sized defect that allows discrimination among grafting materials. Proceedings of the 30th Annual Meeting of the Academy of Surgical Research. September 2014.

107. Pluhar GE. Nicholson A, Luangphakdy V, Bechtold J, Carlson C, Boehm C, Muschler G.

Large animal model of a critical sized defect that allows discrimination among grafting materials. Proceedings of the 12th New Jersey Symposium on Biomaterials Science. October 2014.

108. Pluhar GE. Translating mechanical findings into clinical practice. Proceedings of the Symposium of the American College of Veterinary Surgeons, October 2014.

109. Pluhar GE. Supplementing bone healing. Proceedings of the Symposium of the American

College of Veterinary Surgeons, October 2014.



110. Pluhar GE, Goulart M, Seiler C, Olin M. Immunosuppressive factors, MDSC and arginase are elevated in dogs with malignant gliomas. Abstracts of the Society for Neuro-Oncology Meeting, Nov 2014.

111. Pluhar GE, Olin M, Goulart M, Andersen B, Hunt M, Ohlfest J. Intracerebral IFN-γ does

not enhance the response to vaccine immunotherapy for canine glioma. Abstracts of the Society for Neuro-Oncology Meeting, Nov 2014.

112. Pluhar GE. Robust response of canine meningioma to tumor lysate immunotherapy: A

model for high-grade or recurrent meningiomas. Abstracts of the Society for Neuro-Oncology Meeting, Nov 2014.

113. Boehm C, Luangphakdy V, Pan H, N icholson A, Bechtold J, Carlson CS, Pluhar GE,

Muschler G. Comparison of Bone Marrow Aspiration Site Options in the Spanish Boer Goat – Part of Development of a Rigorous Caprine Tibial Defect Model. Proceedings of theAnnual TERMIS, December 2014.

114. Luangphakdy V, Boehm C, Pan H, Nicholson A, Carlson C, Bechtold JE, Pluhar GE,

Muschler GF. Characterization of a chronic tibial defect model in goats. Proceedings of the Annual TERMIS, December 2014.

115. Luangphakdy V, Boehm C, Zaveri P, Carlson C, Pluhar GE, Bechtold JE, Muschler GF.

Cellular and histological analyses of induced membrane produced in a caprine chronic tibial defect model. Proceedings of the Annual TERMIS, December 2014.

116. Bachelor-Chen J, Baker S, Pluhar GE, Boskey AL, van der Meulen MCH. Parathyroid

hormone improves fatigue life but not whole bone and tissue mechanics. Proceedings of the 42nd Annual Meeting of the Orthopedic Research Society, March 2015.

117. Weinzierl A, Toth F, Pluhar GE, Muschler G, Bechtold JE, Luangphakdy V, Carlson CS.

Histomorphometric comparison of graft efficacy using a caprine chronic tibial defect model. Proceedings of the 42nd Annual Meeting of the Orthopedic Research Society, March 2015.

118. Mesias E, Xiong Z , Pluhar E, Olin M. U se of CD200 blockade inhibitor to enhance

glioma immunotherapy. Proceedings of the 30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer, November 2015.

Grants, Contracts, and Other Funding:

1993-1994 Pluhar GE, Co-investigator. College of Veterinary Medicine Intramural Grants, Washington State University. The Effect of Acute, Unilateral Transverse SinusOcclusion and Shunting on Intracranial Pressure in Normal Dogs, funded.

1996-1999 Pluhar GE, Principal Investigator. National Research Service Award, NationalInstitute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health. Soft Tissue Attachment of Gluteal Musculature to Allografts in Canine



Hip Replacement, funded.

2000-2001 Pluhar GE, Co-investigator. Depuy, Inc. Antibiotic Impregnated Cement, phaseII: Elution characteristics, phase III: Particle size characterization, funded.

2000-2001 Pluhar GE, Primary Investigator. Colorado State University, College Research Council, $4872. The Effects of N-3 Long Chain Polyunsaturated Fatty Acids (fish oil) on MMP-3 and MMP-8 in Canine Osteoarthritis, funded.

2000-2001 Pluhar GE, Co-investigator. Ralston Purina Company. The Effects of N-3 LongChain Polyunsaturated Fatty Acids on Inflammatory Mediators and MatrixMetalloproteinase Levels in Dogs with Osteoarthritis after Surgical Correction ofAcute Anterior Cruciate Ligament Rupture, funded.

2001-2001 Pluhar GE, Co-investigator. Stryker Biotech. Delivery of OP-1 in Enhanced Cement: An Ovine Tibial Ostectomy Study, funded.

2001-2002 Pluhar GE, Principal Investigator. Colorado State University, College ResearchCouncil. Postmortem Evaluation of the Stability of Canine Cemented HipReplacement Implant Wear to Determine Success Rate and Mechanisms ofFailure, funded.

2001-2002 Pluhar GE, Co-investigator. Stryker Biotech. Healing of Large Segmental Tibial Defects with OP-1: An Ovine Equivalency Study, funded.

2001-2002 Pluhar GE, Investigator. US Biomaterials Corp.Comparison of Bioactive BoneGraft Materials against Industry Standards in Rabbits, funded.

2002-2003 Pluhar GE, Principal Investigator. Colorado State University, College ResearchCouncil. Effects of dietary fish oil supplementation via caplets on serum/plasmalevels of matrix metalloproteinases and lameness in dogs with osteoarthritis,funded.

2002-2003 Pluhar GE, Principal Investigator. Hohn-Johnson Research Award, VeterinaryOrthopedic Society. Ex vivo biomechanical testing of modifications to an interlocking nailing system for fixation of unstable canine long bone fractures,funded.

2002-2003 Pluhar GE, Co-investigator. Colorado Commission on Higher Education Grant. Calcium Phosphate Microcarriers for Bone Regeneration: In vitro osteoproduction and ex vivo biomechanical assessment, funded.

2002-2003 Pluhar GE, Co-Principal investigator. Stryker Biotech. Delivery of OP-1 in Tricalcium Phosphate(TCP) Cement: An Ovine Tibial Ostectomy Study, funded.

2003-2004 Pluhar GE, Principal Investigator. Musculoskeletal Transplant Foundation. Assessment of intercalary allograft incorporation with 99TcHDP scans in an ovine model, funded.

2003-2004 Pluhar GE, Co-Investigator. Musculoskeletal Transplant Foundation. Physicalcharacteristics of retrieved massive allografts, funded.



2003-2008 Pluhar GE, Training Faculty. National Institutes of Health, NCRR, T32 RR018719. Comparative Medicine and Pathology Training Grant, funded.

2004-2005 Pluhar GE, Principal Investigator. Musculoskeletal Transplant Foundation. Assessment of intercalary allograft incorporation with 99TcHDP scans in an ovine model, funded.

2004-2009 Pluhar GE, Training Faculty. National Institutes of Health, NIAMS, T32 AR050938. Musculoskeletal Training Grant, funded.

2005 Pluhar GE, Principal Investigator. Stryker Orthopaedics. Measurement of bone defect volume adjacent to acetabular components: A sheep cadaver reproducibility study, funded.

2005 Pluhar GE, Principal Investigator. Hohn-Johnson Research Award, Veterinary Orthopedic Society. Torsional laxity of the canine interlocking nailing system: the effects of locking mechanism and nail hole tolerance. Not funded.

2005 Pluhar GE, Principal Investigator. AO North America Resident Trauma Research Support. Fatigue strength analysis of plates used for radial fracture stabilization in small dogs, funded.

2005-2006 Pluhar GE, Principal Investigator. Intramural Funds, Department of Neurosurgery, University of Minnesota. Gene therapy for canine brain tumors, funded.

2005-2006 Pluhar GE, Principal Investigator. Anika Therapeutics. Evaluation of intra-articular high molecular weight hyaluronic acid for the treatment of canine elbow osteoarthritis, funded.

2006 Pluhar GE, Principal Investigator. Goldhirsh Foundation. Validation and Characterization of Dogs with Spontaneous Gliomas as a Superior Preclinical Model for Human Glioblastoma Multiforme. Not funded.

2006 Pluhar GE, Principal Investigator. Academic Health Center Faculty Research Development Grant, University of Minnesota. Promoting dogs with spontaneous brain tumors as a translational model for novel therapies. Not funded.

2006 Pluhar GE, Principal Investigator. Department of Defense. Healing of critical size defects with allograft or bone substitute supplemented with BMP-2 +/- bone marrow aspirate. Not funded.

2006 Pluhar GE, co-Investigator. Hohn-Johnson Research Award, Veterinary Orthopedic Society. Biofilm prevention using magnesium coated implants. Not funded.

2006-2007 Pluhar GE, Principal Investigator. Stryker Orthopedics. Evaluation of bone response on porous surfaces using a canine total hip model, funded.



2006-2007 Pluhar GE. Principal Investigator. Bayer Healthcare. Dose determination of a novel NSAID in an acute synovitis model in dogs, funded.

2006-2007 Pluhar GE, co-Principal Investigator. Fort Dodge Animal Health. Multi-center clinical efficacy and safety study of 0.2mg/ml rhBMP-2 on absorbable collagen sponges (ACS) implanted in dogs with diaphyseal fractures undergoing standard-of-care surgical management, funded.

2007 Pluhar GE, co-Principal Investigator. UMN CVM Small Companion Animal Research Grant. Fatigue analysis for stack plating techniques to stabilize radial fractures in small dogs, funded.

2007 Pluhar GE, co-Principal Investigator. AO North America Resident Trauma Research Support. Fatigue analysis for stack plating techniques to stabilize radial fractures in small dogs, funded.

2007 Pluhar GE, co-Principal Investigator. UMN CVM Small Companion Animal Research Grant. Effect of interlocking use for fracture fixation in skeletally immature animals. Submitted November 2007. Not funded.

2007 Pluhar GE, co-Principal Investigator. UMN CVM Small Companion Animal Research Grant. Efficacy of intraarticular botulinin toxin for pain relief in dogs with elbow OA. Submitted November 2007. Not funded.

2007 Pluhar GE, co-Investigator. Academic Health Center Faculty Seed Grant, University of Minnesota. Electoacupuncture for palliative therapy in canine hip osteoarthritis. Submitted April 2008, Not funded.

2008 Pluhar GE, co-Principal Investigator. National Institutes of Health, 1 R01 CA136626-01. Overcoming mechanisms of resistance to brain tumor immunotherapy. Resubmitted November 2008, Not funded.

2008-2009 Pluhar GE, Principal Investigator. University of Minnesota Brain Tumor Program. Understanding immunotherapy for canine glioma patients, funded.

2008-2009 Pluhar GE, co-Principal Investigator. Randy Shaver Foundation. Immunotherapy for canine glioma, funded.

2008-2010 Pluhar GE, co-Investigator. University of Minnesota subcontract. National Institutes of Health, 1 R43 NS061364-01A1, $384,076, UMN subcontract. Hollow fiber catheters for drug delivery into the brain, funded.

2009 Pluhar GE, co-Principal Investigator. Department of Defense. Effect of immediate wound antibiotic loading on wound healing and osteomyelitis. Not funded.



2009 Pluhar GE, co-Investigator. National Institutes of Health, NCI, 5 R01 CA10863. Experimental therapeutics for brain cancer. Not funded.

2009-2010 Pluhar GE, Principal Investigator. University of Minnesota Brain Tumor Program. Understanding immunotherapy for canine glioma patients, funded.

2009-2012 Pluhar GE, Principal Investigator. University of Minnesota subcontract. National Institutes of Health, NINDS, 1 U01 NS052465-01A2. UMN subcontract, $ 427,007. Treatment of glioma, funded.

2009-2013 Pluhar GE, Principal Investigator. American Cancer Society, RSG LIB-117294. Role of NK cells in enhancing brain tumor immunotherapy, funded.

2010 Pluhar GE, co-Investigator. National Institutes of Health, NIAMS, AR11-004. Biophysical signals, biomaterial surface characteristics and hMSC differentiation. Not funded.

2010 Pluhar GE, co-Investigator. National Institutes of Health, NIBIB, RFA-OD-09003. In vivo imaging of cartilage biomarker molecules by nanoprobe-based MRI. Not funded.

2010 Pluhar GE, co-Investigator. National Institutes of Health, CBNT, PA-10-067. Experimental therapeutics for brain cancer. Submitted July 2010, Not funded.

2011-2013 Pluhar GE, Principal Investigator. Allergan Research Grants. Does intra-articular botulinum toxin relieve joint pain in dogs with elbow osteoarthritis? funded.

2010-2013 Pluhar GE, Principal Investigator. National Institutes of Health, NINDS, 5R21 NS070955. Understanding and enhancing mechanisms of priming in cancer immunotherapy, funded.

2010-2011 Pluhar GE, co-Principal Investigator. American Brain Tumor Association. Immunotherapy for meningioma, funded.

2010-2014 Pluhar GE, Principal Investigator. University of Minnesota subcontract. National Institutes of Health, NIAMS, 5 R01 AR041325. FT-IR microscopy of mineral structure in osteoporosis, funded.

2011-2014 Pluhar GE, Principal Investigator. National Institutes of Health, PRORP, W81WH-09-OR090480, Improved pre-clinical model for orthopaedic injury, funded.

2011-2013 Pluhar GE, Principal Investigator. University of Minnesota subcontract. National Institutes of Health. Treatment of cerebral edema using ventricular therapy, funded.



2011-2013 Pluhar GE, Principal Investigator. University of Minnesota Comparative Medicine Signature Program Grant. Immunotherapy for Meningiomas: A Prospective, Controlled Clinical Trial, funded.

2011 Pluhar GE, co-Principal Investigator. National Institutes of Health, CNBT, R01 CA166209, Applying Innovations in Immunotherapy to Meningioma. Submitted July 2011, not funded.

2012-2014 Pluhar, GE, co-Investigator. National Institutes of Health, SBIR/STTR. Nanoparticles and nanocapsules for glioma targeting, funded.

2012 Pluhar, GE, Principal Investigator. American Kennel Club Canine Health Foundation OAK Grant. Immunotherapy for Meningiomas: A Prospective, Controlled Clinical Trial. Submitted May 2012, not funded.

2012-2013 Pluhar GE, co-Principal Investigator. UMN CVM Small Companion Animal Research Grant. Effect of interlocking use for fracture fixation in skeletally immature animals, funded.

2012-2013 Pluhar GE, Principal Investigator. University of Minnesota subcontract. National Institutes of Health. User preference evaluation of RVOT system in swine, funded.

2012-2013 Pluhar GE, co-Principal Investigator. Invibio Biomaterials Solutions contract. Evaluation of Tibial Osteotomy Repair using an Intramedullary Nail Fixation System in an Ovine Model, funded.

2013 Pluhar GE, co-Principal Investigator. American Brain Tumor Association, Translational Grant. Translating Canine Meningioma Immunotherapy to Human Clinical Trials. Not funded.

2013 Pluhar GE, co-Investigator. Department of Defense, Peer Reviewed Orthopaedic Idea Development Award, W81XWH-13-PRORP-IDA. Improving skin durability and attachment in amputated limb through innovative tissue and cell-based approaches. Not funded.

2013 Pluhar GE, Principal Investigator. National Canine Cancer Foundation grant,. Investigation of methylation status in dogs with glioma treated with temozolomide. Not funded.

2013 Pluhar GE, Principal Investigator. CVM Comparative Medicine grant. Investigation into a mechanism of immunosuppression by canine glioma cells. Not funded.

2014 Pluhar GE, co-Principal Investigator. National Institutes of Health, NCI, R01



CA193280. Use of CD200/CD200R checkpoint inhibitor in a spontaneous gliomas model, not funded.

2014 Pluhar GE, co- Investigator. American Cancer Society. Understanding and overcoming the immunosuppressive tumor environment, no funded.

2014-2016 Pluhar GE, Principal Investigator. National Canine Cancer Foundation grant. Development of an Autologous Tumor Lysate Vaccine for Immunotherapy for Canine Hemangiosarcoma, funded.

2014-2016 Pluhar GE, co-Principal Investigator. Department of Defense, PRORP Translational Research Partnership Award, W81XWH-12-PROPRP. Optimization of Soft Tissue Management, Spacer Design, and Grafting Strategies for Large Segmental Bone Defects Using the Chronic Caprine Tibial Defect Model, funded.

2014-2016 Pluhar GE, Principal Investigator. American Kennel Club/Canine Health Foundation established investigator award. Immunotherapy for Meningiomas: A Prospective, Controlled Clinical Trial, funded.

2015 Pluhar GE, Principal Investigator. Wipe Out Kids’ Cancer research award. Novel CD200R agonist to improve immunotherapy in canine glioma, not funded.

2015-2016 Pluhar GE, Principal Investigator. Skippy Frank Fund For Life Sciences and Translational Research. Enhancement of vaccine immunotherapy with a CD200 inhibitor in a spontaneous glioma model, funded.

2015-2016 Pluhar GE, Principal Investigator. Randy Shaver Cancer Research and Commumity Fund. Investigation into a Mechanism of Immunosuppression by Canine Glioma Cells, funded.

2015-2017 Pluhar GE, co-Principal Investigator. UMN/Mayo Partnership Research Grant. VSV-cDNA Library Therapy for Treatment of Glioblastoma in Domestic Dogs, funded.

2015-2018 Pluhar GE, investigator on subcontract; Worrell G, PI. NIH NINDS BRAIN Initiative, 1UH2NS095495-01, Neurophysiologically-based brain state tracking and modulation in focal epilepsy, funded.

2015 Pluhar GE, co-Principal Investigator. Department of Defense, PRMRP Focused Program Award, Treatment of Large Segmental Bone Defects - Competitive Assessment and Integration of Technologies and Advancement of Clinical Care, invited full proposal, not funded.

2015 Pluhar GE, co-Investigator. Department of Defense, PRORP Translational Research Award. Optimizing skin-implant interface of osseointegrated device for


Scientific Presentations and Invited Lectures: 1. Ornithine decarboxylase form interconversion. Poster Presentation, XIth International

Congress of Biochemistry, Toronto, Canada, May 4, 1979. 2. Cyclic combination chemotherapy. Continuing Education Seminar, Inland Empire Veterinary

Medical Association, Spokane, Washington, April 21, 1991. 3. Dental diseases and therapeutics (lecture and laboratory). Japanese Summer Program,

College of Veterinary Medicine, Washington State University, Pullman, Washington, 1992. 4. Dental diseases and therapeutics (lecture and laboratory). Japanese Summer Program,

College of Veterinary Medicine, Washington State University, Pullman, Washington, 1993. 5. Humeral fractures. Washington State Annual Conference for Veterinarians, Washington

State University, Pullman, Washington, March 28, 1994. 6. Osteochondroses of the canine forelimb -- Including F ragmented Coronoid Process and

Ununited Anconeal Process. Washington State Annual Conference for Veterinarians,Washington State University, Pullman, Washington, March 28, 1994.

7. Dental diseases and therapeutics (lecture and laboratory). Japanese Summer Program,

College of Veterinary Medicine, Washington State University, Pullman, Washington, 1994. 8. Canine craniodorsal coxofemoral luxation. The Waltham Forum, Video for Small Animal

Practitioners, volume 6, no. 3, 1994. 9. Achondrogenesis in an Akita: A spontaneous mutation. 10th Meeting of the International

Veterinary Radiology Society, Philadelphia, PA, August 18, 1994. 10. Effects of acute, unilateral transverse venous sinus occlusion on intracranial pressure in

normal dogs. 29th Annual Scientific Meeting of the American College of Veterinary Surgeons, Crystal City, VA, October 16, 1994.

11. Meniscal damage and meniscectomy. Washington State Annual Conference for

Veterinarians, Washington State University, Pullman, Washington, March 1995.


the upper limb amputee through innovative mechanical, tissue and cell-based approaches, invited full proposal - pending.

2016 Pluhar GE, co-Principal Investigator. Humor to Fight the Tumor Foundation. Optimization of a canine specific CD200 inhibitor, funded.



12. Lateral release and medial joint capsular modification of the patellofemoral joint using theholmium:YAG laser. Poster Presentation, 43rd Annual Meeting of the Orthopaedic ResearchSociety, San Francisco, CA, February 10, 1997.

13. Three methods of tendon attachment to an allograft/endoprosthetic composite of the proximalfemur in an in vivo canine model: Radiographic and force plate analysis over nine months.9th International Symposium of the International Society of Limb Salvage, New York, NY,September 12, 1997.

14. Three methods of tendon attachment to an allograft/prosthetic composite of the proximalfemur in an in vivo canine model. Meeting of the British Orthopaedic Research Society,Cardiff, Wales, September 24, 1997.

15. Comparison of three methods of gluteal tendon attachment to an allograft/endoprostheticcomposite in total hip arthroplasty: Nine month radiographic and force plate data. 32ndAnnual Scientific Meeting of the American College of Veterinary Surgeons, Orlando, FL,October 18, 1997.

16. Comparison of three methods of gluteal tendon attachment to an allograft/endoprostheticcomposite of the proximal femur in an in vivo canine model. Poster Presentation, 3rd AnnualScientific Meeting of the Connective Tissue Oncology Society, Milan, Italy, November 6,1997.

17. Acetabular fractures (lecture), Canine interlocking nailing (laboratory). Small AnimalOrthopaedics Continuing Education Day on Fracture Fixation, University of Bristol,Langford, Great Britain, March 3-4, 1998.

18. Comparison of three methods of tendon attachment to an allograft/endoprosthetic compositeof the proximal femur in an in vivo canine model. 44th Annual Meeting of the OrthopedicResearch Society, New Orleans, LA, March 17-18, 1998.

19. Surgical treatment of hip dysplasia. Small Animal Orthopaedics Continuing Education Dayon Joint Disease and Surgery, University of Bristol, Langford, Great Britain, June 10, 1998.

20. Comparison of three methods of tendon attachment to an allograft/endoprosthetic compositeof the proximal femur in an in vivo canine model. 1st Annual Department of Veterans AffairsRehabilitation Research and Development National Meeting, Washington D.C., October 1-3,1998.

21. Comparison of three methods of gluteal tendon attachment to an allograft/endoprostheticcomposite during total hip replacement. 33rd Annual Scientific Meeting of the AmericanCollege of Veterinary Surgeons, Chicago, Illinois, October 6-11, 1998.

22. The effect of rhBMP-2 on femoral reconstructions with intercalary allografts – preliminaryresults. 4th Annual Scientific Meeting of the Connective Tissue Oncology Society,Vancouver, B.C., November 6, 1998.



23. The effect of rhBMP-2 on femoral reconstructions with intercalary allografts. 45th AnnualMeeting of the Orthopedic Research Society, Anaheim, CA, February 2, 1999.

24. Hip reconstruction with an allograft/endoprosthetic composite in dogs: Long term results.45th Annual Meeting of the Orthopedic Research Society, Anaheim, CA, February 3, 1999.

25. The effect of rhBMP-2 on femoral reconstructions with intercalary allografts. 10thSymposium of the International Society of Limb Salvage, Cairns, Australia, April 12, 1999.

26. Comparison of three methods of gluteal tendon attachment to an allograft/endoprostheticcomposite during total hip replacement. 11th Annual Colloquium on Aging, University ofWisconsin-Madison, April 22, 1999.

27. Comparison of three methods of tendon attachment to an allograft/endoprosthetic compositeof the proximal femur in an in vivo canine model. 4th Annual Combined Meeting of theMusculoskeletal Tumor Society, Washington D.C., May 9, 1999.

28. Augmentation of femoral reconstructions with intercalary allografts using bonemorphogenetic protein. 34th Annual Scientific Meeting of the American College ofVeterinary Surgeons, San Francisco, CA, October 2, 1999.

29. Small Animal Interlocking Nail Fracture Repair: Special Applications (lecture) andLaboratory. 27th Annual Surgical Forum of the American College of Veterinary SurgeonsSymposium, San Francisco, CA, October 2, 1999.

30. Small Animal Interlocking Nail Fracture Repair: Lecture and Laboratory. 61st AnnualConference for Veterinarians, Colorado State University, Fort Collins, CO, January 8, 2000.

31. Comparison of three methods of gluteal tendon attachment to an allograft/endoprostheticcomposite during total hip replacement. 1st Annual Phi Zeta Research Day, Colorado StateUniversity, Fort Collins, CO, January 29, 2000.

32. Effect of rhBMP-2 on femoral reconstruction using intercalary allografts. 1st Annual PhiZeta Research Day, Colorado State University, Fort Collins, CO, January 29, 2000.

33. Coxofemoral Luxation. Joint Stabilization Operative Techniques Continuing EducationCourse, Colorado State University, Fort Collins, CO, August 24-25, 2000.

34. Small Animal Interlocking Nail Fracture Repair: Lecture and Laboratory. 62nd AnnualConference for Veterinarians, Colorado State University, Fort Collins, CO, January 6, 2001.

35. Small Animal Interlocking Nail Fracture Repair: Lecture and Laboratory. ContinuingEducation Course, Colorado State University, Fort Collins, CO, April 20, 2001.



36. Cruciate Disease – Mechanics, Genetics, Athletics. 11th Annual Symposium of the AmericanCollege of Veterinary Surgeons, Chicago, IL, October 13, 2001.

37. Recent Innovations in Small Animal Orthopedics – Total hip Replacement. 63rd AnnualConference for Veterinarians, Colorado State University, Fort Collins, CO, January 5, 2002.

38. The History of Canine Total Hip Replacement. 2002 SAVMA Symposium, Colorado StateUniversity, Fort Collins, CO, March 16, 2002.

39. Small Animal Interlocking Nail Fracture Repair: Lecture and Laboratory. ContinuingEducation Course, Colorado State University, October 4, 2002.

40. Surgical Management of Elbow Dysplasia. 12th Annual Symposium of the AmericanCollege of Veterinary Surgeons, San Diego, CA, October 17, 2002.

41. Elbow Dysplasia: Diagnosis and Treatment. 64th Annual Conference for Veterinarians,Colorado State University, Fort Collins, CO, January 12, 2003.

42. Comparison of The Model 11 versus Model 22 Interlocking Nailing Systems to StabilizeMid-diaphyseal Tibial Fractures. Poster Presentation. 4th Annual Phi Zeta Research Day,Colorado State University, Fort Collins, CO, January 28, 2003.

43. Comparison of One versus Two Distal Screws in 8mm Interlocking Nails to Stabilize DistalFemoral Fractures. 4th Annual Phi Zeta Research Day, Colorado State University, January28, 2003.

44. Comparison of OP-1 Carriers for Healing Of Tibial Diaphyseal Defects in an Ovine Model.4th Annual Phi Zeta Research Day, Colorado State University, January 28, 2003.

45. Comparison of OP-1 Carriers for Healing of Tibial Diaphyseal Defects in an Ovine Model.49th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, February 2,2003.

46. Tibial Defect Model in Sheep. Large Animal Resident Rounds, University of Minnesota,June 24, 2004.

47. Panel discussion on total hip replacements. 14th Annual Symposium of the AmericanCollege of Veterinary Surgeons, Denver, CO, October 9, 2004.

48. Study of retrieved canine-cemented total hip implants. 14th Annual Symposium of theAmerican College of Veterinary Surgeons, Denver, CO, October 9, 2004.

49. Orthopedic applications of mesenchymal stem cells. 14th Annual Symposium of theAmerican College of Veterinary Surgeons, Denver, CO, October 9, 2004.



50. Delivery of osteogenic protein-1 in tricalcium phosphate cement: An ovine tibial ostectomystudy. 1st Annual Twin Cities Orthopaedic Science Workshop, Hennepin County Medical Center Seminar on Orthopedic Trauma, Minneapolis, MN, November 13, 2004.

51. Interlocking nails for small animal fracture fixation. 108th Annual meeting of the Minnesota

Veterinary Medical Association, Saint Paul, MN, February 3, 2005. 52. Treatment of proximal femoral osteosarcoma with allograft-prosthetic composites. 32nd

Annual conference of the Veterinary Orthopedic Society, March 7, 2005. 53. External Skeletal Fixation – Nomenclature and Biomechanics. 142nd Annual meeting of the

American Veterinary Medical Association. Minneapolis, MN. July 18, 2005. 54. Biostimulation of Fracture Healing. 15th Annual Symposium of the American College of

Veterinary Surgeons, San Diego, CA. October 28, 2005. 55. Diagnosis and Treatment of Iliopsoas Injuries. 15th Annual Symposium of the American

College of Veterinary Surgeons, San Diego, CA. October 29, 2005. 56. Importance of Periosteal Removal on Ovine Critical Size Defect Healing. 2nd Annual Twin

Cities Orthopaedic Science Workshop, Hennepin County Medical Center Seminar onOrthopedic Trauma, Minneapolis, MN, November 19, 2005.

57. Biomechanics of Canine Interlocking Nailing. 109th Annual Meeting of the Minnesota

Veterinary Medical Association, Duluth, MN, February 4, 2006. 58. Canine Femoral Fracture Repair with Interlocking Nailing. 109th Annual Meeting of the

Minnesota Veterinary Medical Association, Duluth, MN, February 4, 2006. 59. Results and Complications of Interlocking Nailing. 109th Annual Meeting of the Minnesota

Veterinary Medical Association, Duluth, MN, February 4, 2006. 60. Importance of periosteal removal on critical size defect healing. 2nd Annual World Veterinary

Congress and 33rd Annual Meeting of the Veterinary Orthopedic Society, Keystone, CO, February 28, 2006.

61. Clinical use of osteogenic protein-1 in veterinary delayed/non union fractures. 2nd Annual

World Veterinary Congress and 33rd Annual Meeting of the Veterinary Orthopedic Society,Keystone, CO, February 27, 2006.

62. Importance of Periosteal Removal on Ovine Critical Size Defect Healing. Poster

Presentation. 52nd Annual Meeting of the Orthopaedic Research Society, Chicago, IL, March19-21, 2006.



63. Clinical use of osteogenic protein-1 in veterinary delayed/non union fractures. PosterPresentation. 16th Annual Symposium of the American College of Veterinary Surgeons,Washington DC. October 7, 2006.

64. Importance of Periosteal Removal on Ovine Critical Size Defect Healing. PosterPresentation. 16th Annual Symposium of the American College of Veterinary Surgeons,Washington DC. October 7, 2006.

65. Is femoral head and neck excision a good option for hip OA? 16th Annual Symposium of theAmerican College of Veterinary Surgeons, Washington DC. October 7, 2006.

66. The use of bone morphogenetic proteins to enhance fracture healing. Grand Rounds,University of Minnesota. November 16, 2006.

67. Postoperative care and complications with TPLOs. UMN CE Course, Saint Paul, MN.November 18, 2006

68. Biomechanics of ILNs UMN CE Course, Saint Paul, MN. November 19, 2006.

69. Instrumentation and application of ILN. UMN CE Course, Saint Paul, MN. November 19,2006.

70. ILN for repair of specific fractures. UMN CE Course, Saint Paul, MN. November 19, 2006.

71. Clinical outcome with ILN use for fracture repair. UMN CE Course, Saint Paul, MN.November 19, 2006.

72. Biomechanics of ILNs Canadian CE, Simon Fraser University, Vancouver, BC. May 20,2007.

73. Instrumentation and application of ILN. Canadian CE, Simon Fraser University, Vancouver,BC. May 20, 2007.

74. ILN for repair of specific fractures. Canadian CE, Simon Fraser University, Vancouver, BC.May 20, 2007.

75. Clinical outcome with ILN use for fracture repair. Canadian CE, Simon Fraser University,Vancouver, BC. May 20, 2007.

76. How to write better multiple-choice questions. Best Practice Institute, University ofMinnesota, Minneapolis, MN. May 17, 2007.

77. Interactive Small Animal Orthopedic Case. 17th Annual Symposium of the American Collegeof Veterinary Surgeons, Chicago, IL. October 19, 2007.



78. Limb salvage using a llografts and allograft-prosthetics. 17th Annual Symposium of the American College of Veterinary Surgeons, Chicago, IL. October 21, 2007.

79. Femoral head and neck ostectomy. 17th Annual Symposium of the American College of

Veterinary Surgeons, Chicago, IL. October 21, 2007. 80. Cranial Cruciate Ligament Rupture and TPLO. Course coordinator and laboratory instructor.

UMN CE Course, Saint Paul, MN. November 17, 2007. 81. Interlocking Nailing in Small Animal Fractures. Course Coordinator and laboratory

instructor. UMN CE course, Saint Paul, MN. November 18, 2007. 82. Biomechanics of ILNs UMN CE Course, Saint Paul, MN. November 18, 2007. 83. Instrumentation and application of ILN. UMN CE Course, Saint Paul, MN. November 18,

2007. 84. ILN for repair of specific fractures. UMN CE Course, Saint Paul, MN. November 18, 2007. 85. Clinical outcome with ILN use for fracture repair. UMN CE Course, Saint Paul, MN.

November 18, 2007. 86. Writing better multiple choice examination questions. University of Minnesota Teachers'

Talks. February 25, 2008. 87. Tips for writing better multiple choice examination questions. University of Minnesota

College of Veterinary Medicine Noon Seminar. April 4, 2008. 88. How to write better multiple-choice questions. Best Practice Institute, University of

Minnesota, Minneapolis, MN. May 21, 2008. 89. In defense of translational medicine. University of Minnesota College of Veterinary

Medicine 1st Annual CMB Debate. June 2, 2008. 90. Mending broken bones in humans, hounds, and horses: Advances in metals, matrices, and

molecular biology. NIH Merck-Merial Veterinary Scholars Symposium, Michigan State University, Lansing, MI. August 1, 2008.

91. Cranial cruciate ligament pathophysiology. Canadian CE course, Toronto, Canada.

September 27, 2008. 92. TPLO complications and postoperative care. Canadian CE course, Toronto, Canada.

September 27, 2008. 93. Interlocking Nailing in Small Animal Fractures. Course Coordinator and laboratory

instructor. Canadian CE course, Toronto, Canada. September 28, 2008.


94. Biomechanics of ILNs. Canadian CE course, Toronto, Canada. September 28, 2008. 95. Instrumentation and application of ILN. Canadian CE course, Toronto, Canada. September

28, 2008. 96. ILN for repair of specific fractures. Canadian CE course, Toronto, Canada. September 28,

2008. 97. Clinical outcome with ILN use for fracture repair. Canadian CE course, Toronto, Canada.

September 28, 2008. 98. Clinical trials for dogs with spontaneous glioma. University of Minnesota Comparative

Biosciences Seminar, Saint Paul, MN. October 15, 2008. 99. Immunotherapy for dogs with brain tumors: Initial results. University of Minnesota Brain

Tumor Program Seminar. Minneapolis, MN. November 17, 2008. 100. Feasibility studies to target brain tumor initiating cells using immunotherapy in dogs with

spontaneous glioma. Society for Neuro-Oncology meeting, Las Vegas, NV. November 22, 2008.

101. Effect of Surface Treatment on Bone In-growth into Porous Titanium Using a Canine

THA Model. Orthopaedic Research Society Meeting, Las Vegas, NV. February 23, 2009. 102. Tritanium™ induces rapid bone ingrowth in a canine hip a rthroplasty model. Orthopaedic

Research Society Meeting, Las Vegas, NV. February 24, 2009. 103. Intraarticular hyaluronic acid increases weight bearing in dogs with elbow OA.

35thAnnual Meeting of the Veterinary Orthopedic Society, Steamboat Springs, CO. March 3, 2009.

104. Saving Batman with immunotherapy. Mini Medical School, University of Minnesota,

Minneapolis, MN. March 16, 2009. 105. Clinical trials for dogs with brain tumors: The Minnesota experience. Society for CNS

Interstitial Delivery of Therapeutics Meeting, Cleveland, OH. September 12, 2009. 106. Canine models of orthopaedic diseases. Annual Meeting of the Interurban Orthopaedic

Society, Minneapolis, MN. October 1, 2009. 107. Successful submissions: Mastering the research grant proposal process. Analyzing

critiques for a successful resubmission. Symposium of the American College of Veterinary Surgeons, Washington DC. October 8, 2009.




108. Fatigue Analysis For Stack Plating. Symposium of the American College of Veterinary Surgeons, Washington DC. October 9, 2009.

109. Tumor responses in dogs with spontaneous astrocytoma and papillary meningioma treated by immunotherapy. Society for Neuro-Oncology Meeting, New Orleans, LA. October 22, 2009.

110. Hyaluronic acid and botulinum toxin for osteoarthritic pain in dogs. CVM Fall Conference, Saint Paul, MN. October 30, 2009.

111. Clinical trials for dogs with brain tumors. CVM Fall Conference, Saint Paul, MN. October 30, 2009.

112. Animal models of brain cancer. Life Science Alley Program – Animal Models of Human Diseases, Saint Paul, MN. November 11, 2009.

113. Creating compelling poster presentations. New Investigators Skills Development Forum, Orthopaedic Research Society, New Orleans, MS. March 8, 2010.

114. Canine brain cancer: Beyond Batman. CVM Research Retreat, University of Minnesota, MN. March 22, 2010.

115. Comparative aspects of brain cancer. Comparative Oncology Group meeting, University of Minnesota, MN. May 13, 2010.

116. Novel treatments for canine brain cancer. Grand Rounds for veterinary technicians, University of Minnesota, MN. August 9 and 12, 2010.

117. Acetabular fractures. World Veterinary Orthopaedic Congress, Bologna, Italy. September 16, 2010.

118. Ulnar osteotomy. World Veterinary Orthopaedic Congress, Bologna, Italy. September 16, 2010.

119. Successful submissions: mastering the research grant proposal process. Analyzing critiques for a successful resubmission. Symposium of the American College of Veterinary Surgeons, Seattle, WA. October 22, 2010.

120. Immunotherapy of spontaneous canine meningioma: A preclinical model. Society for Neuro-Oncology Meeting, Montreal, Canada. November 20, 2009.

121. Acute goat tibial defect model. AFIRM Interim meeting: Synergy of the consortium. Washington DC. December 9, 2010.

122. Chronic goat tibial defect model. AFIRM Interim meeting: Synergy of the consortium. Washington DC. December 9, 2010.



123. Nailing the Interview. Invited lecture, Orthopedic Research Society meeting: Professional development series. Long B each, CA. January 13, 2011.

124. Minnesota Brain Tumor Clinical Trials. Invited lecture, Annual meeting of the Minnesota

Veterinary Medical Association. Minneapolis, MN. February 10, 2011. 125. Meet the Experts Booth. Annual meeting of the Minnesota Veterinary Medical

Association. Minneapolis, MN. February 10, 2011. 126. Fracture session: Introductory case. 37thAnnual Meeting of the Veterinary Orthopedic

Society, Snowmass, CO. March 10, 2011. 127. Clinical Trials for Dogs with Glial Tumors: Beyond Batman. Invited lecture, Neurology

Specialty Symposium of the American College of Veterinary Internal Medicine, Denver, CO. June 15, 2011.

128. Bone Regeneration Strategies in a Chronic Caprine Tibial Defect Model. Advanced

Technology Applications for Combat Casualty Care, Fort Lauderdale, FL. August 16, 2011. 129. UMN Canine Meningioma Clinical Trial. Grand Rounds, University of Minnesota,

September 22, 2011. 130. Dogs with Brain Tumors: Traditional and Non-Traditional Therapies. Invited lecture,

Young Scientist Roundtable, Eden Prairie Council for Gifted and Talented, Wayzata, MN. October 4, 2011.

131. Comparative Animal Models of Human Diseases: Translational Medicine. Invited

lecture, Lake Forest College, Lake Forest, IL. November 3, 2011. 132. Surgery and Immunotherapy I mproves Survival over Surgery Alone for Canine

Meningiomas. Society for Neuro-Oncology Meeting, Orange County, CA. November 19, 2011.

133. Development of a chronic caprine tibial defect model. Armed Forces Institute for

Regenerative Medicine All Hands meeting, St. Petersburg, FL. February 15, 2012. 134. Canines curing cancer: Transforming brain tumor therapy – K eynote presentation. Neuro-

Oncology Symposium: Basic Discovery Accelerating Groundbreaking B rain tumor Therapy, Minneapolis, MN. May 17, 2012.

135. Interlocking Nailing in Small Animal Fractures. Course Coordinator and laboratory

instructor. CE course at the Symposium of the American College of Veterinary Surgeons, Washington DC. October 31, 2012.


163. Canine companions as a model for brain tumor research. Invited presentation. Summit

on Animals, Public Health, and Ethics, Johns Hopkins University, Baltimore, MD, December 9, 2015.

164. Addition of a CD200 inhibitor to autologous tumor lysate vaccines for dogs with high-

grade glioma. Invited presentation. 3rd Neuro-Oncology Symposium, Minneapolis, MN, May 9, 2016.

165. Surgery and vaccine-based immunotherapy for canine glioma. Invited presentation.

Annual Forum of the American College of Veterinary Internal Medicine, Denver, CO. June 9, 2016.

166. Clinical trial of autologous tumor lysate vaccines after surgical resection for the treatment

of meningioma in dogs. 1st Annual International Research Meeting on Meningioma, Toronto, Canada. June 17, 2016.

Teaching Responsibilities Didactic Lectures/Laboratories and Clinical Rotations to Professional Students Mercy College (1989-1990): Surgical Wet Laboratory 3 hr Didactic/demonstration; lecture/laboratory Washington State University (August 1 1991 to June 30, 1995): VM 472 Surgery I Didactic lecture 1 hr VM 560 Small Animal Medicine Senior clinical local practice rotation VM 474 Surgery Laboratory I Small animal surgical exercises 4 hr VM 565 Small Animal Surgery Senior clinical orthopedic and soft tissue surgery rotation VM 566 Small Animal Surgery Elective Elective senior clinical orthopedic and soft tissue surgery rotation University of Wisconsin-Madison (May 1, 1997 to July 31, 1998): VM 938-644 Small Animal Orthopedic Elective Elective senior orthopedic surgery rotation Colorado State University (May 1, 1999 to April 30, 2003):




136. Canines curing cancer: Transforming brain tumor therapy. 2nd Skippy Frank Conference on Comparative Translational Medicine, Menlo Park, CA. February 8, 2013.

137. Development of a chronic caprine tibial defect model. AAOS/OTA/SOMOS/ORS

Extremity War Injuries VIII: Sequelae of Combat Injuries, Washington DC. February 12, 2013.

138. Autologous vaccine therapy to control invasive canine meningioma. AANS/CNS 10th

Biennial Satellite Tumor Symposium, New Orleans, LA. April 27, 2013. 139. Canine Glioma Clinical Trials Experience at the University of Minnesota. 2nd Bi-Annual

Veterinary Neurosurgical Society Symposium, Portland, OR. August 9, 2013. 140. Surgery/immunotherapy improves survival over surgery alone to treat canine

meningioma. 2nd Bi-Annual Veterinary Neurosurgical Society Symposium, Portland, OR. August 9, 2013.

141. Characterization of a chronic tibial defect model in goats. Military Health System

Research Symposium, Ft. Lauderdale, FL. August 14, 2013. 142. Vaccine immunotherapy for canine meningioma: Clinical and translational aspects. 2nd

Neuro-Oncology Symposium, Minneapolis, MN, September 27, 2013. 143. Vaccination with autologous glioma lysate induces tumor-reactive IgG antibody response

and increases survival in dogs with glioma. 2nd Neuro-Oncology Symposium, Minneapolis, MN, September 27, 2013.

144. Immunotherapy of canine meningioma. Symposium of the American College of

Veterinary Surgeons, San Antonio, TX. October 25, 2013. 145. Surgery and immune/gene therapy for canine gliomas. Symposium of the American

College of Veterinary Surgeons, San Antonio, TX. October 25, 2013. 146. Imaging of brain tumors. Symposium of the American College of Veterinary Surgeons,

San Antonio, TX. October 26, 2013. 147. Canines Curing Cancer: Treatments for Man’s Best Friend Leading to Help for Humans.

University of Minnesota MinneCollege, Scottsdale, AZ. February 22, 2014. 148. Perspectives on Ethics of Animal Use, RAM/PAM Club Discussion Series, University of

Minnesota, St. Paul, MN. April 1, 2014. 149. Spontaneous GBM in a research macaque, All CVM Case Discussion Series, University

of Minnesota, St. Paul, MN. April 16, 2014.



150. Effect of Grafting Materials on Bone Healing in a Chronic Caprine Tibial Defect Model. Military Health System Research Symposium, Ft. Lauderdale, FL. August 20, 2014.

151. Large Animal Model of a Critical Sized Defect that Allows Discrimination among

Grafting Materials. 30th Annual Academy of Surgical Research Meeting, Minneapolis, MN. September 19, 2014.

152. Large Animal Model of a Critical Sized Defect that Allows Discrimination among

Grafting Materials. 12th New Jersey Symposium on Biomaterials Science, New Brunswick, NJ. October 6, 2014.

153. Translating Biomechanical Findings into Clinical Practice. Symposium of the American

College of Veterinary Surgeons, San Diego, CA. October 17, 2014. 154. Supplementing Bone Healing. Symposium of the American College of Veterinary

Surgeons, San Diego, CA. October 18, 2014. 155. Development and Validation of a Chronic Caprine Tibial Defect Model. Grand Rounds,

University of Minnesota, October 30, 2014. 156. Robust response of canine meningioma to tumor lysate immunotherapy: A model for

high-grade or recurrent meningiomas. Annual Meeting of the Society for Neuro-Oncology, November 16, 2014.

157. Treating canine brain tumors: The Minnesota experience. Invited presentation.

Research Animal Medicine Club, University of Minnesota, January 28, 2015. 158. Small animal bandaging a nd splinting lecture and laboratory. Invited presentation.

Annual Meeting of the Student American Veterinary Medical Association, Minneapolis, Minnesota, March 19, 2015.

159. Treating canine brain tumors: The Minnesota experience. Invited presentation. Annual Meeting of the Student American Veterinary Medical Association, Minneapolis, Minnesota, March 21, 2015.

160. Development of the caprine chronic tibial defect model. Invited presentation. Semi-

Annual Meeting of the ASTM for Tissue Engineering Methods and Protocols, Anaheim, California, May 20, 2015.

161. Translational immunotherapy for brain tumors. Invited presentation. 1st Annual Meeting

of the NIH NCI Comparative Brain Tumor Consortium, Washington DC, September 14, 2015.

162. The Science of Bone Healing: How goats can help your patients. Invited presentation.

Twin Cities Foot and Ankle Conference for the Minnesota Podiatric Medical Association, St. Paul, Minnesota, November 13, 2015.


VM 616 Functional Anatomy, Canine forelimb and hindlimb Elbow dysplasia 4 hr

Hip dysplasia 4 hr VM749 Clinical Sciences III, Small Animal Orthopedics

Elbow dysplasia 1 hr Hip dysplasia 1 hr Coxofemoral luxation 1 hr Cruciate disease 1 hr Meniscal damage 1 hr

VM 786AV Junior Practicum, Surgical Principles Laboratory Knot tying and manual skills lab 4 x 4 hr

Live animal labs 4 x 4 hr VM 733 Principles of Surgery

Bone biomechanics 1 hr Fracture classification 1 hr Bone healing 1 hr External skeletal fixation 1 hr External coaptation 1 hr

VM 774 Small Animal Medicine and Surgery II

Angular limb deformities 1 hr Arthrodesis 1 hr Osteomyelitis 1 hr Non-union and delayed unions 1 hr Miscellaneous orthopedic diseases 1 hr

(HOD, HO, CMO, Panosteitis) University of Minnesota (May 1, 2003 to present): CVM 6011 Freshman Professional Skills Ethics – Animal Use in Veterinary Teaching 1 hr CVM 6321 Surgery/Anesthesia/Critical Care (2003-2008)

Suture Materials 1 hr Surgical Instrumentation 1 hr Suture Patterns (lecture) 1 hr Suture laboratory 2 x 4 hr Grafts and Plastic Surgery 1 hr Surgical Infections 1 hr Antibiotics in Surgery 1 hr Spay/Neuter Laboratory 6 x 4 hr

CVM 6420 Musculoskeletal System (2007)

Osteoarthritis 1 hr




Orthopedic Examination 1 hr Introduction to Arthroscopy 1 hr Tendon and Ligament Injuries 1 hr Interlocking Nailing 1 hr Orthopedic Examination Laboratory 2 x 4 hr

CVM 6420 Musculoskeletal System (2008-2014)

Osteoarthritis 1 hr Small Animal Orthopedic Examination 1 hr Developmental Orthopedic Diseases 2 hr Fracture Classification 1 hr Fracture Biomechanics 1 hr Interlocking Nailing 1 hr Angular Limb Deformities 1 hr Splints and Bandages 1 hr Joint Luxations 1 hr Nonunion and Delayed Unions 1 hr Small Animal Orthopedic Examination lab 2 x 3 hr Pins and wires in fracture repair lab 2 x 2 hr Stifle arthrotomy/extracapsular stabilization lab 2 x 2 hr

CVM 6927 Small Animal Surgery I (2015-current)

Small Animal Orthopedic Examination lab 2 x 3 hr Bandaging & splinting lab 2 x 3 hr Bone healing, grafting, nonunions 1 hr Bone growth/Angular Limb Deformities 1 hr Developmental Orthopedic Diseases 2 hr Fracture Classification & biomechanics 1 hr Fracture repair methods 1 hr Joint luxation & limb salvage 1 hr

CVM 6410 Digestive Disorders (2003-2007) GI Terminal Laboratory 6 x 4 hr CVM 6424 Small Animal Orthopedics – A dvanced Block Interlocking Nailing in Canine Fracture Repair 1 hr

Angular Limb Deformities 1 hr CVM 6663 Small Animal Surgery – course coordinator Senior clinical surgery rotation

Didactic Lectures/Laboratories to Graduate Students

Colorado State University (May 1, 1999 to April 30, 2003):

VS 612 Plastic and Reconstructive SurgerySkin flaps and grafts 1 hr



Distal extremity wounds and tendon repair 1 hr VS 630-631 Orthopedic Surgery Gait analysis 1 hr

Total joint replacement 1 hr VS 630-631 Neurology Intracranial surgery 1 hr University of Minnesota (May 1, 2003 to present): VMED 8681 Advanced Small Animal Surgery

Arthroscopy 8 hr VMED 8694 Research in Veterinary Surgery Directed Studies 20-80 hr VMED 5190 Seminar and Presentation Development Poster Presentations 2 hr VMED 5242 Advanced Small Animal Pathobiology I II Bone Healing/Enhancement of Fracture Healing 1 hr CMB 8303 Comparative Models of Disease Animal Models of Brain Tumors 2 hr VMED 8685 Neurosurgery

Intracranial Surgery 2 hr Brain surgery laboratory 5 hr

OBIO 8012 Bone Healing and Bone Grafting 3 hr Clinical Rounds/Seminars: Washington State University: AAHA Small Animal Surgery rounds, coordinator and presenter for freshman, sophomore and junior veterinary students. Provided a discussion of clinical cases 4 hours/month, 1993-1995

Surgery Journal Club, coordinator and occasional presenter for interns, residents and faculty. Provided discussion of recent publications and clinical cases 1 hour/week, 1993-1995

Miscellaneous Teaching Aids:

Video teaching tool: DVD of canine coxofemoral lameness as a tool to teach veterinary students how to diagnose orthopedic disease of the hip joint with Dr. Randy Fitch, 2003.



Video teaching tool: DVD of canine cruciate lameness as a tool to teach veterinary students how to diagnose orthopedic disease of the stifle joint with Dr. Randy Fitch, 2003.

Video teaching tool: DVD of canine shoulder lameness as a tool to teach veterinary students how to diagnose and treat infraspinatus contracture with Dr. Randy Fitch, 2003

Video teaching tool: DVD "The Innovative Tibial Plateau Leveling Osteotomy Procedure"

Video teaching tool: DVD " Interlocking Nailing System Wet Lab Procedure"

Electronic Jeopardy - Orthopedic Diseases

Television segment for the local news channels on treating Batman the first patient in the clinical trial treating brain tumors with surgery and immunotherapy and gene therapy, 2008.

Television segment for “Survivor Tales” for the Foundation for Biomedical Research on Treating dogs with brain tumors: Implications for people with brain tumors, 2010.

Television segment for the Daily Planet on the Discovery Channel, Canadian Television on Rilley’s Journey about a beagle treated for a meningioma with surgery and immunotherapy, 2010.

Television segment for the local news channels on treating dogs with brain tumors with surgeryand immunotherapy and gene therapy, 2011.

Television segment for the CBS Early Show for national airing, on treating dogs and people with brain tumors with surgery and immunotherapy and gene therapy, 2011.

Dakota’s Brain, 30-minute television segment, Bench to Bedside TV series. Season 1, Australian Broadcasting Corporation, 2012.

Television segment for the local news channels celebrating the100th dog treated in the Brain Tumor Clinical Trials Program, 2013.

Television segment for the local news channels about Booster, the service dog with primary frontal sinus squamous cell carcinoma that was treated with vaccine immunotherapy. 2013.

Student and Resident Advising

Washington State University:

Senior Paper, Sally Anderson, The importance of nutritional therapy in the treatment of felineidiopathic hepatic lipidosis, 1992

Senior Paper, Lisa Bennett, Neuromuscular collapse in a dog, 1992

Senior Paper, Patrick C. Black, Preventative behavior medicine for dogs, 1992

American Association of Animal Hospitals, Student Chapter, 1992-1994



Colorado State University:

Matthew Rooney, SA surgery resident, M.S. co-advisor 1999–2002, M.S. awarded May 2002,Diplomate ACVS 2003

Chengcheng Liu, M.S. co-advisor 2000–2002, M.S. awarded August 2002

Rod Hansen, Ph.D. committee member 2000–2003, Ph.D. awarded Spring 2003

Simon T. Kudnig, SA surgery resident, M.S. committee member 2000–2003, awarded Spring2003, Diplomate ACVS 2004

Carolyn Skurla, Ph.D. committee member 2001–2003, Ph.D. awarded August 2002

Jana Haynie, M.S. committee member 2001–2003, M.S. awarded Spring 2003

Tatiana Motta D.V.M., M.S. major advisor 2001-2003, awarded Spring 2004

Michael R. Reems, SA surgery resident, M.S. major advisor 2001-2004, awarded Spring 2004, Diplomate ACVS 2005

Brandon Santoni, M.S. committee member 2002–2003, M.S. awarded Summer 2003

University of Minnesota:

Cheri Nielsen M.S., D.V.M., M.S. major advisor, 2003-2006, awarded June 2006, Diplomate ACVS 2007

John Bevan D.V.M., M.S. major advisor, 2004-2007, did not complete degree, Diplomate ACVS 2009

Jeff Seaman D.V.M., M.S. major advisor, 2005-2008, awarded September 2010, Diplomate ACVS 2010

Brian Rose D.V.M., M.S. major advisor, 2006-2009, Diplomate ACVS 2010

Andrea Sotirakopoulos D.V.M., M.S. committee member, 2005-2007, awarded August 2007

Margaret McNulty, Ph.D. committee member, 2006-2010, awarded April 2010

Duane Robinson, D.V.M., Ph.D. committee member, 2007-2011,awarded May 2011, resident advisor, 2009-2011

Olivia Kilian, D.V.M./Ph.D. major advisor, 2007-2011

Kristina Kiefer, D.V.M., Ph.D. major advisor, 2008-2014

Michelle Goulart, D.V.M., Ph.D. major advisor, 2008-2014



Eric Battjes, D.V.M. 2009, faculty and research project mentor

Diana Davila, D.V.M., Residency and research project mentor, 2008-2011

Justin Uhl, D.V.M., Residency and research project mentor, 2010-2014

Katie Murphy, Ph.D., Post-doctoral traineeship mentor, 2011-2013

Brian Andersen, M.D./Ph.D. candidate, Research project mentor, 2011-2013

Erin Corbin, D.V.M., Research project mentor, 2012-2015

Zoe Zhang, M.D., Neurosurgery residency project mentor, 2012-2013

Chris Thomson, D.V.M. student, Summer Scholar mentor and research advisor, 2013

Jeff MacLellan, D.V.M., Residency and research project mentor, 2013-2016

Rickard Kohler, D.V.M., Research project mentor, 2013-2016

Philip Allen, D.V.M., Residency and research project mentor, 2014-2017

Elisabet Ampudia Mesia, B.S., Ph.D. committee member, 2015-2019

Emily Truckenbrod, D.V.M., Ph.D. advisor, 2015-2019

COMMITTEES:

Colorado State University:Departmental:

Departmental Reorganization Steering Committee, 2000

Resident Graduate Committee, 2000-2003

Scholarship and Awards Committee, 2001-2003

Veterinary Teaching Hospital:

Central Supply/Materials Management Committee, 2000-2003

University of Minnesota:University:

Infrastructure Task Force, Saint Paul campus, 2005

Clinical Research Advisory Board, 2005-2007



Faculty Senate, 2012-2016

Research Animal Resources User Group, 2013

Invited presenter, University of Minnesota Foundation Discovery Showcase, 2013

Executive Committee, Brain Tumor Program, 2013-present

Institutional Animal Care and Use Committee, 2014-2017

Collegiate:

Admissions and Scholastic Standing, 2004-2008

Graduate Programs Education Strategic Planning committee, Jan 2008 – Mar 2009

VBS Chair Search Committee, Sep 2008 - Dec 2008 (committee suspended)

Research Committee, Jul 2009 – Jul 2012

CVM representative, Director for the Institute for Engineering and Medicine Search Committee,October 2010-present

VMED Program Advisory Committee, 2005-2010

VMED PAC Task Force, 2005

Clinical Investigation Center Steering Committee, Chair, 2005-2009

MRI Work Group, Jul 2005 - Jan 2006

Focus Group for Research, Feb 2005 - Jun 2007

Associate Dean of Research Search Committee, Jul 2006 - Apr 2007

CVM Dean Search Committee, Jul 2007 - Jul 2008

Administrative Review Committee, 2009

College Representative to meet with President Kaler during the Campus Crawl, 2011

Poster judge, Musculoskeletal Training Grant Combined Retreat, Silverwood Park, St. Anthony, MN, 2011

Poster judge, Points of Pride Research Days, College of Veterinary Medicine, University of Minnesota, 2011

Reviewer, Small Animal Companion Research Grants, College of Veterinary Medicine, University of Minnesota, 2009-2012




Research Committee, Jul 2014 – Jul 2017


Departmental:

Ophthalmology Search Committee, Sept 2003 - Feb 2005

Small Animal Surgery Resident Search Committee, Chair, 2006-2011, member 2011-present

Graduate Faculty – Comparative and Molecular Biosciences, senior member

Graduate Faculty – Veterinary Medicine, senior member

Residency and Postgraduate Training Committee, 2013-present

Merit Review, Research and Scholarship Committee, 2004-2006

Orthopedic Surgeon Search Committee, Feb 2005 - Jun 2006

Residency and Postgraduate Training Committee, 2006-2009

Soft Tissue Surgeon Search Committee, Chair, Jun 2006 - Dec 2006

Merit Review Reform Committee, 2006-2007

Promotion and Tenure Committee, 2009-2012, Chair, 2010-2012

Medical Imaging Faculty Search Committee, 2011

Small Animal Surgeon Search Committee, 2013

Small Animal Surgery Resident Search Committee, Chair, 2013

Small Animal Surgery Resident Search Committee, Chair, 2015

External Academic and Administrative Service:

1999 Surgical Symposium Resident’s Forum Committee, ACVS


2001-2003 Program Director, ACVS, Small Animal Surgery, Colorado State University

2001-2004 Resident Credentialing Committee, ACVS

2002 Surgical Symposium Seminar Chair, Elbow Dysplasia, ACVS



2002-2003 Research Awards Committee, VOS

2004-present Reviewer, Journal of Orthopaedic Research

2004 Surgical Symposium Seminar Chair, Musculoskeletal Tissues, ACVS

2005-present Reviewer, Veterinary Medicine

2005-present Reviewer, Journal of Biomedical Materials Research

2005 Surgical Symposium Seminar Chair, Musculoskeletal Tissues, ACVS

2005-2007, Research Grant Committee, grant reviewer, Musculoskeletal Transplant 2010-present Foundation

2005-2007 Item Writer, National Board of Veterinary Medical Examiners

2005-present Reviewer, Veterinary Surgery

2004-2009 Program Director, Small Animal Surgery, University of Minnesota, ACVS

2007 Surgical Symposium Seminar Chair, Joint Salvage, ACVS

2007-2010 Research Committee, American College of Veterinary Surgeons Chair (2010)

2008 Surgical Symposium Seminar Chair, Knee Surgery I, ACVS

2008 Surgical Symposium Seminar Chair, Knee Surgery II, ACVS

2008-2012 Membership Committee, Orthopaedic Research Society Vice Chair 2009-2010, Chair 2010-2011, ex officio Chair 2011-2012

2010-2011 Board of Directors, Orthopedic Research Society

2009-2010 Volunteer Appointment Committee, Orthopaedic Research Society

2008-2011 Scientific Program, Veterinary Orthopedic Society Assistant Chair (2009-2010), Chair (2010-2011)

2008-2011 Board of Directors, Veterinary Orthopedic Society

2009 Co-Chair, Fall Small Animal Symposium, University of Minnesota

2009-2010 Planning Committee, World Veterinary Orthopedic Conference

2009-present Reviewer, Veterinary and Comparative Orthopaedics and Traumatology



2009- present Reviewer, American Journal of Veterinary Research

2011-present Editorial Board, ISRN Orthopedics

2011 Chair and Organizer, Professional Development Series, Orthopedic Research Society

2011-2014 Organizing Committee, World Veterinary Orthopedic Conference

2012-2013 Organizing Committee, International Conference One Medicine One Science

2012-2013 Organizing Committee, 2nd Neuro-Oncology Symposium

2013 AO Research Review Committee, grant reviewer, AO Research Foundation

2013 Leader, Task group, New Animal Models of Bone Repair, American Society for Testing and Materials (ASTM)

2013-2014 Chair, Neurosurgery session, World Veterinary Orthopaedic Congress

2013 Chair, Brain Surgery session, Surgical Symposium ACVS

2012-present Program Director, University of Minnesota, Small Animal Surgery ACVS

2013 Nominee, Secretary-Elect/Secretary and Board of Directors, Orthopaedic Research Society


2014-present Member, Cellular, Tissue and Gene Therapies Advisory Committee, Food and Drug Administration

2014-2018 Residency Program Compliance Committee, ACVS

2015-present Organizing member, Comparative Brain Tumor Consortium, NIH NationalCancer Institute

2015 Member working group for Animals, Public Health and Ethics, Group on the Integration of the Relationship of Animals, Public Health and Ethics (GIRAPHE), Johns Hopkins University


curriculum vitae grace elizabeth pluhar, dvm, phd ...€¦ · grace elizabeth pluhar, dvm, phd,...

Documents