curriculum vitae date: name: office address · curriculum vitae . date: may 29, 2019 name: nicholas...

CURRICULUM VITAE DATE: May 29, 2019 NAME: Nicholas M. Ponzio, Ph.D. OFFICE ADDRESS: Department of Pathology and Laboratory Medicine Rutgers, The State University of New Jersey Rutgers New Jersey Medical School (NJMS) 185 South Orange Avenue P.O. Box 1709 Newark, New Jersey 07103-2484 Voice: (973) 972-5238 Fax: (973) 972-7293 E-mail: [email protected] CITIZENSHIP: United States of America

As of July 1, 2013 New Jersey Medical School and Graduate School of Biomedical Sciences are part of Rutgers University Biomedical and Health Sciences (http://rbhs.rutgers.edu/)

EDUCATION: 1968 B.A. Seton Hall University, South Orange, NJ 1970 M.S. Seton Hall University, South Orange, NJ 1973 Ph.D. State Univ New York, Downstate Medical Center, Brooklyn, NY RESEARCH FELLOWSHIPS: 1973-74 Postdoctoral Fellow, Dept Microbiology, Albert Einstein College of Medicine, Bronx, NY 1974-76 Postdoctoral Fellow, Dept Pathology, New York University Medical Center, New York, NY ACADEMIC APPOINTMENTS: Northwestern University Medical, Dental, and Graduate Schools, Chicago, IL 1976-80 Assistant Professor of Microbiology and Immunology; Medical School 1977-80 Assistant Professor; Graduate School 1979-80 Assistant Professor of Pathology; Medical & Graduate Schools 1980-81 Associate Professor of Microbiology & Immunology and Pathology; Medical, Dental and Graduate Schools University of Medicine and Dentistry of New Jersey (UMDNJ), Newark, NJ 1981-87 Associate Professor of Pathology; New Jersey Medical School (NJMS) and Graduate School of Biomedical Sciences (GSBS) 1987-2013 Professor of Pathology and Laboratory Medicine; NJMS and GSBS 1990-2013 Professor of Microbiology and Molecular Genetics (Joint Appointment) 2000-2013 Vice Chair, Department of Pathology and Laboratory Medicine 2000-2013 Associate Director and Chief Operating Officer; Neurological Institute of

New Jersey (NJMS-affiliated institute for clinical services, research and education related to neurological diseases

mailto:[email protected]

http://rbhs.rutgers.edu/

May 2019 Nicholas M. Ponzio, Ph.D.

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Rutgers, The State University of New Jersey 2013-present Professor of Pathology and Laboratory Medicine; NJMS and GSBS 2013-present Professor of Microbiology and Molecular Genetics (Joint Appointment) 2013-2014 Vice Chair, Department of Pathology and Laboratory Medicine 2013-2014 Associate Director and Chief Operating Officer; Neurological Institute of

New Jersey HOSPITAL APPOINTMENTS: 1981-2007 Adjunct Staff; UMDNJ-University Hospital; Newark, NJ

VISITING APPOINTMENTS: 1986, 1987 Visiting Investigator-The Jackson Laboratory, Bar Harbor, ME 1991-92 Visiting Scientist--The Imperial Cancer Research Fund; London, UK 2013 Visiting Professor, University of Sharjah, United Arab Emirates 2015-16 Visiting Professor, Stony Brook University, Stony Brook, NY CERTIFICATION: 1988-present Diplomate of the American Board of Medical Laboratory Immunology AWARDS AND HONORS: 1979-84 Research Career Development Award (CA00833) Nat'l Cancer Institute 1982, 84 & 95 UMDNJ Exceptional Merit Awards 1988 & 1991 NJMS Service and Teaching Awards

2003 Induction into UMDNJ Master Educators’ Guild President-elect (2004-05); (2013-2014) President (2005-06) 2009 UMDNJ – NJMS Faculty of the Year Award 2012 Excellence in Teaching Award (UMDNJ Foundation) 2013 Rutgers – NJMS Distinguished Career Award 2018 Excellence in Teaching Award (New Jersey Health Foundation)

BOARDS OF DIRECTORS/TRUSTEES; EDITORIAL BOARDS: American Cancer Society, New Jersey Division, Union County Unit: 1984-87 Board of Managers and Executive Committee 1986-87 Secretary American Cancer Society, New Jersey Division:

1986-91 Board of Trustees and Executive Committee 1986-2007 Ruth Estrin Goldberg Memorial for Cancer Research: Scientific Advisory Board 1987-91 NJ State Commission on Cancer Research: Scientific Advisory Board 1988-2001 NJ Organ and Tissue Sharing Network: Scientific Advisory Board 1988-89 Veteran's Administration Merit Review Board


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Immunology Study Section 1984-86 Editor, Cancer Update (Newsletter of the American Cancer Society, NJ Division) 1996-98 Editorial Board; Clinical Immunology & Immunopathology Section Editor for new ‘Molecule of the Month’ feature 1997-present Editorial Board; International Immunopharmacology 1998-2001 Associate Editor, AMLInteractions (Newsletter of the Association of Medical Laboratory Immunologists) 1999-2000 Associate Editor; AMLInteractions (Newsletter of the Association of Medical Laboratory Immunologists) 1999-2007 Scientific Advisory Board; New Jersey Cord Blood Resource Center

2008-present Commissioner; New Jersey Commission for Brain Injury Research 2014-2018 Board of Trustees; Institute of Medicine and Public Health of New Jersey 2016-2018 Co-Editor-in-Chief; International Journal of Translational Science

PROFESSIONAL POSITIONS: 1988-89 Program Director, UMDNJ/NIH-OPRR joint conference: "PHS Guidelines for Humane Care & Use of Laboratory Animals" 1988-89 Co-organizer, Third Annual Conference/Workshop, NJ State Commission on Cancer Research 1994-2001 Director, Cancer Research Training Program; NIH Grant T32CA09665 SERVICE ON MAJOR COMMITTEES: American Cancer Society New Jersey Division: 1982-88 Professional Education Committee (1986-88; Chairman) 1988-91 Public Issues Committee Union County Unit of New Jersey Division: 1984-87 Public Education Committee (1984-86; Chairman)

American Association of Immunologists (AAI) 1989-92 Member, Education Committee 1990-93 Member, FASEB Education Committee--AAI representative

Association of Medical Laboratory Immunologists (AMLI) 1995-present Member, Education Committee 1998-2001 Associate Editor, AMLInteractions (Association Newsletter)

American Association of University Professors (AAUP) 1990-91 President, UMDNJ Council of Chapters (all units) 2014-16 Board of Governors

AAUP UMDNJ-NJMS/NJDS Chapter 1988-89 Treasurer 1989-90 Vice-President 1990-91 President


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Master Educators’ Guild (UMDNJ and Rutgers University) 2004-2007 President-elect; President; Immediate Past President 2013-2016 President-elect President; Immediate Past President Rutgers University and Rutgers Biomedical and Health Sciences (RBHS) 2014-present RBHS Faculty Council 2015-present Rutgers University Senate

UMDNJ and Rutgers – New Jersey Medical School (NJMS): 1981-91 Animal Care and Use Committee: 1985-89 Chairman Dean's Advisory Committees: 1981-82; 85-87 Administer American Cancer Society Institu Research Grant 1984-86; 88-90 Administer NIH Biomedical Research Grants 1984-86; 88-90 Review NJMS grant applications for UMDNJ Foundation 1990-91; 98-99 Cancer Advisory and Planning Committee 1999- 2007 Oversight of Institutional Animal Care and Use Committee 1984-86; 89-91; 92-94; 2006-07 Faculty Comm on Appointments and Promotions (FCAP) 1985 Chairman, LCME Subcommittee on Graduate Education 1985-88; 91-96 Subcommittee of Basic Science Course Coordinators 1986-88 Curriculum Comm for BA/MD Program 1986-87 Committee to review guidelines for appointments & promotions 1987-88 Chairman, Search Comm for Micro & Mol Gen Dept Chair 1987-91; 95-97 Bylaws Committee (Chair, 1995-97) 1988-89 Student Affairs Committee 1988-90 Institutional Planning and Development Committee 1988-89 Search Comm for Pathology Dept Chair (Departmental Rep) 1995-97; 2008-10 NJMS Faculty Council 1998- 2010 Cancer Education Committee 2000- 2002 Academic Programs and Policies Committee 2000- 2004 Autism Forum 2006- 2007 Faculty Comm on Appointments and Promotions (FCAP) 2006- 2007 Search Comm for Research Animal Facility Director 2006- 2010 Transition Team for migration of GSBS into NJMS administration 2006- 2007 President, New Jersey Medical School Faculty Organization 2007- 2008 Vice-President, New Jersey Medical School Faculty Organization 2009- 2011 Faculty Affairs Committee 2009- 2011 UMDNJ-wide Faculty Senate Development Committee 2010- present Flow Cytometry Core Advisory Committee 2010-2011 Search Committee for NJMS Dean 2010-2011 Committee to revise bylaws for UMDNJ-Grad Sch Biomed Sci 2010-present NJMS Curriculum Evaluation Committee 2011-13; 2014-present NJMS Faculty Council 2011- 2013 Vice-President, New Jersey Medical School Faculty Organization Departmental:


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1981-82 Chairman, Graduate Admissions Committee 1981-82 Graduate Progress Committee 1982-present Combined Graduate Studies Committee: 1982-86 Chairman 1981-82 Faculty Search Committee 1983-85 Pathology Seminar Committee 1984-89 Space Committee (Chairman: 1986-89) 1984-87 Recruitment Committee 1986-87 Steering Committee 1989-91 Chairman, Departmental Appointments/Promotions Comm UMDNJ – Graduate School of Biomedical Sciences (GSBS): 1981-86; 2000-14 GSBS Executive Council 1981-86 Admissions Review Committee

1983-84 Self-Assessment Comm for Middle States Assoc accreditation 2006- 2011 Transition Team for migration of GSBS into NJMS administration 2010- 2011 GSBS-wide Bylaws Committee 2010- 2012 GSBS-wide Admissions Committee

UMDNJ – School of Health Related Professions (SHRP): 1984-94 Curriculum Committee, Medical Technology Program

MEMBESHIPS IN PROFESSIONAL SOCIETIES (Initial year of membership):

American Society of Zoologists (1969) American Association for the Advancement of Science (1970) American Association of Immunologists (1976) Chicago Association of Immunologists (1976; President 1979-80) American Society for Investigative Pathology (1981) (formerly the American Association of Pathologists) American Association for Cancer Research (1981) New York Academy of Sciences (1983) Scientists Center for Animal Welfare (1985) American Association for Laboratory Animal Science (1986) Clinical Immunology Society (1987; Charter member) Society for Leukocyte Biology (1987) (formerly the Reticuloendothelial Society) Sigma Xi (1987) Association of Medical Laboratory Immunologists (1987) New Jersey Academy of Science (1988) Society for Neuroscience (2008) International Society for Autism Research (2009) Psychoneuroimmunology Research Society (2009) American Association of Medical Colleges (2014) Association for Medical Education in Europe (2014)


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Invited Reviewer: Manuscripts: Grants: J Immunology NIH: National Cancer Inst Cellular Immunology Nat'l Science Foundation Int’l Immunopharmacology American Cancer Society Cancer Research Veteran's Administration J Cancer Res and Clin Oncol Autism Speaks J Nat'l Cancer Inst; Eur J Cancer Clin Immunol & Immunopathol

J Immunol Methods Aging: Immunol & Infectious Dis

Cancer Detection and Prevention Experimental Biology & Medicine Brain, Behavior, and Immunity SPONSORSHIP OF CANDIDATES FOR POSTGRADUATE DEGREE:

Years Trainee Degree Title of Thesis/Research Project 1977-79 C. Myers M.S. Experimental B cell lymphomas 1977-80 K. Fitzgerald Ph.D. Natural killer function in B cell lymphomas 1984-87 R. Alisauskas Ph.D. Host-tumor interactions in B cell lymphomas 1984-87 A. Alonso Ph.D. Lymphocyte responses to syngeneic antigens 1985-90 G. Erianne M.S. Monoclonal antibodies therapy for experimental B cell lymphomas 1984-86 R. Prince (Co-advisor) Ph.D. Tumor therapy by hyperthermia and a Rutgers University calcium channel blocker 1986-91 M. Buckley Ph.D. Mechanisms of Ig allotype suppression 1991-97 H. Wajchman Ph.D. Analysis of tumor activated T cells 1992-98 J. Delmanto Ph.D. IL-12 induced cytotoxicity vs. a syngeneic B cell lymphoma 1995-98 G. Erianne Ph.D. Regulation of viral superantigen gene expression in B lymphoma cells

*2000-03 W. Simmons Ph.D. Development of tumor-responsive TH1 cell lines for adoptive immunotherapy *William Simmons was selected to receive the 2003 Stanley S. Bergen Jr. Award given to one student from each of the eight UMDNJ schools.


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2000-02 V. Papasozomenou M.S. Cytokine genotype analysis in transplant donors

and recipients 2001-05 L. Luistro Ph.D. Tumor inhibitory mechanisms of HER2- specific monoclonal antibody (Herceptin) 2002-05 P. Singh Ph.D/M.S. Development of CTL cell lines for adoptive immunotherapy 2003-05 J. Hu M.S. Immunological aspects of autism 2006- 08 C. So M.S. Immunological aspects of autism 2007- 2012 M. Mandal Ph.D. Influence of maternal immune response on the development of autism SPONSORSHIP OF POSTDOCTORAL FELLOWS: Years Trainee Degree Title of Thesis/Research Project 1985-90 Tao-Zhen Lin, M.D. Postdoctoral Natural killer activity in experimental Res. Assoc. B cell lymphomas 1987-90 H. Fernandes, Ph.D. Postdoctoral Influence of lymphokines on Res. Assoc. lymphoma growth 1995-96 H. Batarseh, M.D. Postdoctoral Therapeutic use of Human Umbilical Res. Assoc. Cord Blood cells 2010- 12 S. Basak Postdoctoral Role of fetal programming on vulnerability for Res. Assoc. development of immune disorders 2012-13 Pan Zhang Postdoctoral Role of fetal programming on vulnerability for Res. Assoc. development of immune disorders MENTORSHIP OF JUNIOR FACULTY MEMBERS 2015 – 2017 Sarah Morelli, M.D., Ph.D.; NJMS Department of Obstetrics & Gynecology 2017 – present Dominic Del Re, Ph.D.; NJMS Department of Cell Biology & Molecular Medicine MAJOR TEACHING RESPONSIBILITIES (Course Director/co-director): At Northwestern University Medical School 1977-80 Introductory Immunology (Graduate students) 1978-80 Fundamentals of Immunology (Medical students) 1979-80 Immunology for Medical Technologists

1980 Tumor Immunology (Graduate Students)

At University of Medicine and Dentistry of New Jersey/Rutgers University 1980-2000 Advanced Topics in Immunology 1985-1992 Fundamentals of Immunology (NJMS and GSBS) 1993-2013 Infection & Host Response (NJMS – formerly Fundamentals of Immunology) 1993-2013 Cellular & Molecular Immunology (GSBS)


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1993-1997 Ethics in Science and Research (GSBS) 1997-2007 Molecular & Immunopathologic Mechanisms of Cancer (GSBS) 2000-2012 Molecular & Cellular Biology – Immunology Core (GSBS) 2003-2013 Molecules to Medicine: The Business of Science (GSBS) 2013-present Foundations of Body Systems (NJMS) 2013-present Cellular/Molecular Immunology: Rutgers School of Graduate Studies (SGS) 2013-present Molecules to Medicine: The Business of Science (SGS) 2017-present Communicating Science Rutgers (SGS) 2017-present Communicating Science Workshops (Rutgers Office of Academic Affairs) PRINCIPAL CLINICAL AND HOSPITAL SERVICE RESPONSIBILITIES: 1982-1991 Co-director, Cancer Markers Laboratory 1984-1991 Director, Cellular Immunology Laboratory 1993-2000 Director, Cytokine Laboratory, Division of Serology

MAJOR CURRENT AND PAST ADMINISTRATIVE RESPONSIBILITIES: 1. Associate Director & Chief Operating Officer; Neurological Institute of New Jersey

(UMDNJ-affiliated institute for clinical services, research and education related to neurological diseases). Major oversight responsibility for organization and development of this campus-wide institute during its creation, early phases of growth, and evolution.

2. Program Director--Cancer Research Training Program: Major effort to obtain funding

(NIH/NCI Grant T32CA09665) and establish this new interdepartmental program, recruit high quality trainees, and strengthen the representation of cancer research among the academic programs offered on the Newark campus.

3. Vice Chair for Academic Programs (Department of Pathology and Laboratory Medicine):

Major oversight responsibility for departmental educational programs, including efforts to coordinate clinical and basic science educational programs within the department, and maximize cross-fertilization among residents and graduate students

4. Course Director--Fundamentals of Immunology: Major contribution to the initiation of this

course into the NJMS and GSBS curricula. Continuing effort to further develop this course to include contemporary Clinical Immunology for medical students.

5. Cancer Markers Laboratory: Establishment of a unit within the Clinical Pathology

Laboratories at University Hospital to perform biochemical and immunological assays that detect "markers" of cancer cells, including hormones, enzymes and other natural products elaborated by tumor cells, as well as surface antigenic determinants expressed by malignant cells.

6. Graduate Program in Experimental Pathology: Major effort directed toward an overall

strengthening of the predoctoral program through vigorous student recruitment, upgrading of existing elective courses and addition of new courses.

7. Chairman, Animal Care and Use Committee (ACUC): Major oversight responsibility of the

ACUC at the time that the new guidelines mandated by the US Public Health Service and the


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newly enacted amendments to the federal Animal Welfare Act for the use of animals in biomedical research needed to be implemented by the university.

MAJOR RESEARCH INTERESTS: • Role of fetal programming on vulnerability for development of immune-mediated disorders • Contribution of immunological mechanisms to autism spectrum disorders • Cellular and molecular approaches to investigate the etiology, diagnosis and

treatment of B cell lymphomas • Hematopoiesis and stem cell transplantation using umbilical cord blood cells

PATENT APPLICATIONS:

• Use of human umbilical cord blood for adoptive therapy (Filed December 1998) • Compositions & methods for inhibiting the effects of reverse immune surveillance in

lymphoproliferative disease (Filed April 2002) COMMUNITY OUTREACH ACTIVITIES

• 2018- present Rutgers Day event: Communicating Science exhibit GRANT SUPPORT: GRANTS AS PRINCIPAL INVESTIGATOR (Total direct costs indicated): At Northwestern University Medical School 1976-77 Effect of antigen localization on immunologically specific B cells; Northwestern Univ. Research. Comm. ($5,000) 1977-78 Membrane determinants mediating isogeneic lymphocyte interactions. American Cancer Society, IL Division; ($20,000) 1977-78 Host-tumor relationship of SJL mice to syngeneic lymphomas. Northwestern Univ. Cancer Ctr. ($6,000) 1978-80 Lymphocyte responses to syngeneic antigens. NIH - Natl Cancer Inst. ($122,000) 1979-80 Research Career Development Award, NIH - Natl Cancer Inst. ($72,000) 1978-81 Models of lymphocyte migration and localization. NIH - Natl Inst Allergy Immunol Dis. ($114,000) At University of Medicine and Dentistry of New Jersey/Rutgers University 1981-84 Transfer of Research Career Development Award to UMDNJ ($108,000) 1981-82 Lymphocyte responses to syngeneic antigens. American Cancer Society - NJ Division. ($20,000) 1981-82 NIH Institutional Biomedical Research Support Grant: Experimental lymphomas ($9,708) 1981-83 Biochemical analysis of membrane antigens on neoplastic B cells. UMDNJ Foundation ($19,903) 1982-87 Studies of allotype suppression in the mouse. Merck & Co.


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($50,000) 1982-83 Effect of lymphokines on lymphoma growth. American Cancer Society Institutional Research Grant ($4,000) 1982-94 Experimental models of lymphoma. Ohl Cancer Fund (Total award -- $109,129) 1983-86 Role of naturally cytotoxic cells in models of lymphoma. NIH - Natl Cancer Inst. (01 - 03 years; $162,000) 1984-88 Influence of Catrix-S on immune responses, Lescarden, Inc. ($200,000) 1984-86 Influence of lymphokines on growth of B cell derived tumors, NJ Commission on Cancer Research ($73,000) 1985-87 Mechanisms of allotype suppression, March of Dimes ($51,273) 1985-87 Predoctoral Fellowship award to R Alisauskas; National Cancer Cytology Center ($30,000). 1986-90 Role of naturally cytotoxic cells in models of lymphoma, NIH - Natl Cancer Inst (renewal; years 04-07; $356,407) 1987-96 Dependence of lymphoma growth on "Reversed Immunological Surveillance," Charles Edison Fund ($135,000) 1987-88 NIH Institutional Biomedical Research Support Grant: Allotype Suppression ($9,000) 1988-89 Planning/conduct of UMDNJ/NIH joint conference on implementation of Public Health Service guidelines for care and use of laboratory animals ($9,900) 1990-93 Influence of the host immune system on lymphoma development, NJ Commission on Cancer Research ($74,000). 1991-93 Shared Instrumentation Grant for a Gamma Irradiator; NIH Division of Research Resources ($180,000). 1993-96 Role of Tumor Activated Blast cells in the development and growth of B cell lymphomas, UMDNJ Foundation ($25,000). 1994-99 Molecular and Immunopathologic Mechanisms of Cancer. NIH - Natl Cancer Inst Training Grant ($717,163). 1995-97 Use of human umbilical cord blood cells for adoptive therapy. NJ State Comm on Cancer Research ($42,000). 1995-96 Use of human umbilical cord blood cells for cancer therapy. The Milheim Foundation for Cancer Research ($10,000). 1995 Sponsor for Summer Undergraduate Fellowship award to Andrew Klein. NJ State Commission on Cancer Research ($2,800). 1996-98 Cancer immunotherapy using human umbilical cord blood cells. Elsa U. Pardee Foundation ($60,000). 1996-01 National Research Service Award; NIH - Natl Inst Gen Med Sci. MARC Fellowship for MD/PhD candidate John Barnes; Faculty Advisor ($113,697). 1996-98 Cancer immunotherapy using human umbilical cord blood cells. UMDNJ Foundation ($25,000).


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1998-02 Cancer immunotherapy using human umbilical cord blood cells. Elsa U. Pardee Foundation Renewal ($110,000). 2002-04 Contribution of immunological mechanisms to autism spectrum disorders National Alliance for Autism Research ($120,000).

2002-04 Predoctoral Fellowship award to William Simmons; New Jersey Commission on Cancer Research ($36,000).

2003-05 Influence of CpG compounds on growth of B cell lymphomas. Dynavax Technologies Corp. (pilot study - $20,000)

2005-08 Influence of immune mechanisms on development of autism spectrum disorders. New Jersey Governor’s Council on Autism (200,000)

2007-09 Cytokine polymorphisms in mothers of children with autism The Autism Center at UMDNJ - New Jersey Medical School ($2,500)

2008-10 Influence of maternal cytokines on activation of the innate immune system as a factor in the development of autism. Autism Speaks (Fellowship award for M. Mandal - $64,000)

2008-11 Influence of the maternal immune response on the development of autism. Autism Speaks ($450,000)

2008-09 New rodent models of autism. UMDNJ Foundation – High impact collaborative award ($70,000)

2009-12 Influence of maternal cytokines during pregnancy on effector and regulatory T helper cells as etiological factors in autism ($330,000)

2013-2015 Development of new course - Re-defining clinical roles across a spectrum of health care settings. National Science Foundation Subaward through its Science Education for New Civic Engagements and Responsibilities (SENCER) program ($3,000)

2016-2017 Providing biomedical Ph.D. students with advanced communication skills for career transitions. The Burroughs Wellcome Fund ($36,166)

GRANTS AS CO-INVESTIGATOR: 1986 Recirculatory automatic watering system for the Research Animal Facility (Co-investigator with Dr. H. Villaverde), Biomedical Research Support Grant ($34,000) 1987 Shared Instrumentation Grant for a Cell Sorter; NIH-Division of Research Resources (P.I.-J Oleske; $400,000) 1988-89 Planning/conduct of the 3rd Annual Conference; New Jersey State

Commission on Cancer Research ($23,321) 1997 Shared Instrumentation Grant; New equipment for Flow Cytometry

Laboratory; NIH-Div Research Resources (P.I.-T Denny; $400,000) 2000-01 Shared Instrumentation Grant; Upgrade equipment for Flow Cytometry

Laboratory; NIH-Div Research Resources (P.I.-T Denny; $357,000) 2003-06 Psychoneuroimmunology of T cell activation; NIH-Natl Inst Mental Health

(P.I. S Zalcman; $125,000) 2005-06 Development of a screening method to predict immunogenic peptides for

vaccines; NIH (P.I.- P Rameshwar; $100,000)


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2007-09 The effect of supervised exercise on immune, physical, and psychological status in breast cancer patients undergoing chemotherapy; The Foundation of UMDNJ (P.I.- B Gladson; $20,000)

2012-2015 Effects of TLR9 Ligands on the Inflammatory Response, Bladder Dysfunction and Chronic Pain in Spinal Cord Injury. New Jersey Commission on Spinal Cord Injury (PI: S Elkabes; $598,449)

2015-2016 Development of an empathy and clarity rating scale for medical students and the effect of improvisation-informed communication skills curriculum on end-of-first-year OCSE performance (PI: C Terregino – Rutgers RWJMS; $5,000)

2016 – 2017 Cell restoration project. Advanced ReGen Medical Technologies (PI: Pranela Rameshwar – NJMS; $2,995,000)

2019 – 2022 Restoring the brain: an approach to treating Alzheimer’s Disease. Benjamin Ayer Foundation (PI: Pranela Rameshwar – NJMS; $2,400,000)

GRANTS AS ASSOCIATE DIRECTOR, NEUROLOGICAL INSTITUTE OF NEW JERSEY 2000-01 Seed grant for pilot projects in basic neuroscience F.M. Kirby Foundation ($50,000) 2001-02 Award for program project grants in basic neuroscience F.M. Kirby Foundation ($100,000) 2002-03 Renewal award for program project grants in basic neuroscience F.M. Kirby Foundation ($150,000) PUBLICATIONS: Refereed Original Journal Articles 1. Ponzio NM, Speirs RS: Lymphoid cell dependence of the eosinophil response to antigen. III. Comparison of the rate of appearance of two types of memory cells in various lymphoid tissues at different times after priming. J Immunol 110:1363-1370, 1973. 2. Ponzio NM, Speirs RS: Lymphoid cell dependence of the eosinophil response to antigen. IV. Effects of in vitro X-irradiation on the adoptive transfer of anamnestic cellular and humoral responses to tetanus toxoid. Proc Soc Exp Biol Med 145:1178-1180, 1974. 3. Ponzio NM, Speirs RS: Lymphoid cell dependence of the eosinophil response to antigen. V. Evidence for the induction of separate memory cells mediating cellular and humoral responses to tetanus toxoid. Zeithschrift Immunitatsforschung 146:405-413, 1974. 4. Ponzio NM, Speirs RS: Lymphoid cell dependence of the eosinophil response to antigen. VI. The effect of selective removal of T or B lymphocytes on the capacity of primed spleen cells to adoptively transfer immunity to tetanus toxoid. Immunology 28:243-251, 1975. 5. Ponzio NM, Finke JH, Battisto JR: Adult murine lymph node cells respond blastogenically to a new differentiation antigen on isologous and autologous B lymphocytes. J Immunol 114:971-975, 1975.


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6. Romano TJ, Ponzio NM, Thorbecke GJ: Graft-versus-host reaction in F1 mice induced by parental lymphoid cells: Nature of the recruited cells. J Immunol 116:1618-1623, 1976. 7. Finke JH, Ponzio NM, Battisto JR: Isogeneic and allogeneic lymphocyte interactions may be controlled by cell surface immunoglobulin tropism. Cell Immunol 26:284-294, 1976. 8. deKruyff RH, Ponzio NM, Thorbecke GJ: Migratory patterns of B lymphocytes. IV. Effect of anti-Ig pretreatment on follicular localization of radioactively labeled murine spleen and bone marrow cells. Cell Immunol 30:282-299, 1977. 9. Ponzio NM, Lerman SP, Chapman-Alexander JM, Thorbecke GJ: Properties of transplantable reticulum-cell sarcomas (RCS) in SJL/J mice. IV. minimal development of cytotoxic cells in spite of marked proliferation to syngeneic RCS cells in vivo and in vitro. Cell Immunol 32:10-22, 1977. 10. Ponzio NM, David CS, Shreffler DC, Thorbecke GJ: Properties of transplantable reticulum cell sarcomas (RCS) in SJL/J mice. V. Nature of RCS surface antigen which induces proliferation of normal SJL/J T cells. J Exp Med 146:132-145, 1977. 11. deKruyff RH, Ponzio NM, Thorbecke GJ: Evaluation of the possible role of B cell receptors in the tendency of B cells to migrate into follicles in mice and chickens. Eur J Immunol 7:237-241, 1977. 12. Ponzio NM, Chapman-Alexander JM, Thorbecke GJ: Properties of reticulum cell sarcomas (RCS) in SJL/J mice. VI. Characterization of lymphoid cells which proliferate in response to syngeneic RCS. Cell Immunol 41:157-171, 1978. 13. Ponzio NM, Chapman-Alexander JM, Thorbecke GJ: Transfer of memory cells into antigen pretreated hosts. I. Functional detection of migration sites for antigen-specific B cells. Cell Immunol 34:79-92, 1977. 14. Fitzgerald KL, Ponzio NM: Natural killer cell activity in reticulum-cell sarcomas (RCS) of SJL/J mice. Cell Immunol 43:185-191, 1979. 15. Ponzio NM: Lymphocyte responses to syngeneic antigens. I. Enhancement of the murine autologous mixed lymphocyte response by polyethylene glycol. Cell Immunol 49:266-282, 1980. 16. Finke JH, Fyfe DA, Del Villano BC, Butler GH, Ponzio NM: Characterization of "foreign" alloantigen-like specificities on a murine lymphoma cell line. Transpl Proc 12:53-58, 1980. 17. Katz IR, Lerman SP, Ponzio NM, Shreffler DC, Thorbecke GJ: Growth of SJL/J derived transplantable reticulum-cell sarcoma as related to its ability to induce T cell proliferation in the host. I. Dominant negative genetic influences of parental haplotype in F1 hybrids of SJL/J mice. J Exp Med 151:347-361, 1980.


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18. Scott JW, Ponzio NM, Orosz CG, Finke JH: H-2K/H-2D, as well as M1s and I-region associated antigens stimulate helper factor(s) involved in the generation of cytotoxic T lymphocytes. J Immunol 124:2378-2383, 1980. 19. Ponzio NM, Baine Y, Thorbecke GJ: Localization of functional memory B cells at sites of antigen localization and its relationship to local aspects of immunological memory. Proc Reticuloendothelial Society. Phylogeny of Immunological Memory (ed by MJ Manning) pp. 291-307, Elsevier/North Holland Biomedical Press, Amsterdam, 1980. 20. Ponzio NM, Fitzgerald KL, Thorbecke GJ, Vilcek J: Type II interferon production by reticulum-cell sarcomas from SJL/J mice. Ann. NY Acad Sci 350:157-167, 1980. 21. Fitzgerald KL, Ponzio NM: Natural killer cell activity in reticulum-cell sarcomas (RCS) of SJL/mice. II. Analysis of RCS-associated NK activity. Int J Cancer 28:627-634, 1981. 22. Fitzgerald KL, McMaster JS, Ponzio NM: Natural killer cell activity in reticulum-cell sarcomas (RCS) of SJL/J mice. III. Characterization of the effector cell within RCS that mediates NK lysis. Int J Cancer 28:635-645, 1981. 23. Baine Y, Thorbecke GJ, Ponzio NM: Transfer of memory cells into antigen pretreated hosts. II. Influence of localized antigen on the migration of specific memory B cells. Eur J Immunol 12:990-996, 1981. 24. Scheid MP, Chapman-Alexander JM, Hayama T, Katz IR, Lerman SP, Nagler C, Ponzio NM, Thorbecke GJ: Identification of transplantable reticulum cell sarcomas in SJL/J mice as belonging to the B cell lineage. In: B lymphocytes in the Immune Response (eds. Klinman, Mosier, Scher and) pp. 475-482, Elsevier/North Holland, Amsterdam, 1981. 25. Ponzio NM: Similarities between the syngeneic mixed lymphocyte response and lymphoma-induced T cell proliferation in SJL/J mice. Behring Institute Mitteilungen. 72:28-36, 1983. 26. Brown PH, Cone RE, Ponzio NM, Jones PP, Thorbecke GJ: Nature of T cell stimulating molecules on SJL/J lymphomas. Immunogenetics 18:399-413, 1984. 27. Katz IR, Nagase F, Bell MK, Ponzio NM, Thorbecke GJ: Suppression and enhancement of immune responses in vivo in SJL and F1 hybrid mice by injection of gamma-irradiated syngeneic lymphoma cells. J Natl Cancer Inst 72:125-132, 1984. 28. Ponzio NM, Hayama T, Nagler C, Katz IR, Hoffmann MK, Gilbert C, Vilcek J, Thorbecke GJ: I-A restricted interaction of normal lymphoid cells and SJL lymphoma (RCS) leading to lymphokine production. II. Rapid production of antibody enhancing factor, IL-2, and immune interferon. J Natl Cancer Inst 72:311-320, 1984.


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29. Hayama T, Ponzio NM, Nagler C, Vilcek J, Thorbecke GJ: I. A restricted interaction of normal lymphoid cells and SJL lymphoma (RCS) leading to lymphokine production. III. Relative roles of RCS and normal lymphoid cells in lymphokine production. J Natl Cancer Inst 72:321-331, 1984. 30. Nagase F, Ponzio NM, Waltenbaugh C, Katz I, Thorbecke GJ: Experimental artifacts of biological interest. I. Nonspecific immune modulating effects of ascites fluid and hyperimmune sera in vivo. Cellular Immunol 90:92-102, 1985. 31. DeKruyff RH, Brown PH, Thorbecke GJ, Ponzio NM: Characterization of SJL T cell clones responsive to syngeneic lymphoma (RCS): RCS-specific clones are stimulated by activated B cells. J Immunol 135:3581-3586, 1985. 32. Alisauskas R and Ponzio NM: In vivo growth inhibition of Ia+ lymphomas in SJL mice treated with I-As-reactive monoclonal antibody. Immunopharmacology 12:1-9, 1986. 33. Ponzio NM, Alonso A, Alisauskas, RM: Dependence of lymphoma growth on "Reversed Immunological Surveillance." Pathol and Immunopathol Res. 6:1-21, 1987. 34. Lasky JL, Ponzio NM and Thorbecke GJ: Characterization and growth requirements of SJL lymphomas. I. Development of a B cell growth factor (BCGF) dependent in vitro cell line, cRCS-X. J Immunol 140:679-687, 1988. 35. Fine BP, Ponzio NM, Denny TM, Maher E and Walters TR: Sodium deficient diet restricts tumor growth in mice. Cancer Research 48:3445-3448, 1988. 36. Stavnezer J, Lasky JL, Ponzio NM, Scheid MP and Thorbecke GJ: Reticulum cell sarcomas of SJL/J mice have rearranged immunoglobulin heavy and light chain genes. Eur J Immunol. 19:1063-1069, 1989. 37. Alisauskas RM and Ponzio NM: T helper cell specific monoclonal antibody inhibits growth of B cell lymphomas (RCS) in syngeneic SJL/J mice. Cell Immunol 119:286-303, 1989. 38. Alisauskas RM, Friedman C and Ponzio NM: Influence of T helper cell specific monoclonal antibody on progressive growth of B cell lymphomas in SJL/J mice: Correlation of acute treatment dosage with tumor dormancy or complete remission in long-term survivors. Cancer Commun. 2:33-43, 1990. 39. Ende NE, Giuliani D, Ende M and Ponzio NM: Production of human to mouse xenografts by umbilical cord blood. Life Sciences. 46:1373-1380, 1990. 40. Tsiagbe VK, Asakawa J, Ponzio NM and Thorbecke GJ: Paraproteins and primary lymphoma in SJL mice. II. Primary lymphomas do not produce paraprotein. Cell Immunol. 129:503- 512, 1990.


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41. Tao-Zhen L and Ponzio NM: Syngeneic B lymphoma cells provide a unique stimulus to natural killer (NK) cells in genetically low-NK SJL/J mice. J Leukocyte Biol. 49:48-57, 1991. 42. Tao-Zhen L, Fernandez H, Yauch R, Ponzio NM and Raveche E: IL-10 production in a CD5+ B cell lymphoma arising in an anti-CD4 monoclonal antibody reated SJL/J Mouse. Clin Immunol and Immunopathol. 65:10-22, 1992. 43. Ende N, Ponzio NM, Athwal R, Ende M and Giuliani DC: Murine survival of lethal irradiation with the use of human umbilical cord blood. Life Sciences. 51:1249-1253, 1992. 44. Ende N, Ponzio NM, Giuliani D, Ende M, Bagga PS, Godyn J and Athwal RS: The effect of human cord blood on SJL/J mice after chemoablation and irradiation and its possible clinical significance. Immunological Investigations. 24:999-1012, 1995. 45. Ponzio NM, Tsiagbe VK and Thorbecke GJ: Superantigens related to B cell hyperplasia. Springer Seminars in Immunopathology. 17:285-306, 1996. 46. Wang X, Ponzio NM and Studzinski GP: Long-term exposure of HL-60 cells to 1,25-dihydroxyvitamin D3 reduces their tumorigenicity: A model for cancer chemoprevention. Proc Soc Exp Biol Med. 215:399-404, 1997. 47. Rameshwar P, Smith I, Ende N, Batarseh H and Ponzio NM: Endogenous hematopoietic reconstitution induced by human umbilical cord blood cells in immunocompromised mice: Implications for adoptive therapy. Experimental Hematology. 26:1-11, 1999. 48. Czarneski J, Yi-Chu L, Ende N, Ponzio NM and Raveche E: Effects of cord blood transfer on the hematopoietic recovery following sublethal irradiation in MRL lpr/lpr mice. Proc Soc Exp Biol Med. 220:79-87, 1999. 49. Ende N, Lu S, Mack R and Ponzio NM: The feasibility of using blood bank-stored cord blood, unmatched for HLA, for marrow transplantation. Amer J Clin Pathol. 111:773-781, 1999. 50. Kim BS, Bahk YY, Kang H-K, Yauch RL, Kang J-A, Park M-J and Ponzio NM: Diverse fine specificity and receptor repertoire of T cells reactive to the major VP1 epitope (VP1230-250) of Theiler’s virus. J Immunol. 162:7049-7057, 1999. 51. Erianne G, Wajchman J, Yauch R, Tsiagbe VK, Kim BS and Ponzio NM: B cell lymphomas of C57L/J mice; the role of Natural Killer cells and T helper cells in lymphoma development and growth. Leukemia Research. 24:705-718, 2000. 52. Thorbecke GJ and Ponzio NM: Reverse Immune Surveillance: An adaptive mechanism used by tumor cells to facilitate their survival and growth. Seminars in Cancer Biology. 10:327-330, 2000. 53. Ponzio, NM and Thorbecke, GJ: Requirement for reverse immune surveillance for the growth of germinal center derived murine lymphomas. In: Reverse Immune Surveillance: An adaptive


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mechanism used by tumor cells to facilitate their survival and growth. (GJ Thorbecke and NM Ponzio, eds.) Seminars in Cancer Biology. 10:331-340, 2000 54. Chong SY, Zhang M, Lin Y-C, Coffman F, Garcia Z, Ponzio NM, and Ravechè E. The growth regulatory role of B-cell-specific-activator-protein (BSAP) in NZB malignant B-1 cells. Cancer Immunology and Immunotherapy. 50:41-50, 2001. 55. Sen N, Simmons WJ, Thomas RM, Erianne G, Zhang DJ, Jaeggli NS, Huang C, Xiong X, Tsiagbe VK, Ponzio NM and Thorbecke GJ: META-controlled, env-initiated transcripts encoding superantigens of murine Mtv29 and Mtv7 and their possible role in germinal center B cell lymphomagenesis. J Immunol. 166:5422-5429, 2001. 56. Wajchman J, Simmons WJ, Klein A, Koneru M and Ponzio NM: Interleukin-12-induced cytotoxicity against syngeneic B cell lymphomas of SJL/J mice. Leukemia Research. 26:577-590, 2002. 57. Natelson BH, Haghighi MH, and Ponzio NM: A review of the evidence on the presence of immune dysfunction in chronic fatigue syndrome. Clinical and Diagnostic Laboratory Immunology. 9:747-752, 2002. 58. Chen K, Shiflett SC, Ponzio NM, He B, Elliott BS and Keller SE: A preliminary study of the effect of external Qigong on lymphoma growth in mice. J Alternative and Complementary Medicine. 8:615-621, 2002. 59. Potian JA, Aviv H, Ponzio NM, Harrison JS and Rameshwar P: Veto-like activity of mesenchymal stem cells (MSC): Functional discrimination between cellular responses to alloantigens and recall antigens. J Immunol. 171:3426-3434, 2003. 60. Simmons WJ, Koneru M, Mohindru M, Thomas R, Cutro S, Singh P, DeKruyff RH, Inghirami G, Coyle A, Kim BS, Ponzio NM: Tim-3+ T-bet+ Tumor Specific TH1 Cells Co-localize With and Inhibit Development and Growth of B Cell Lymphomas. J Immunol. 174:1405-1415, 2005. 61. Kang HS, Potian JA, Habib M, Chan J, Abavana C. Ponzio NM, Rameshwar P: A paradoxical role for IFN-γ in the immune properties of mesenchymal stem cells during viral challenge. Exp Hematol. 33:796-803, 2005. 62. Chan JL, Bonilla LM, Pierobon N, Taborga M, Tang KC, Ponzio NM, Rameshwar P: Antigen presenting property of mesenchymal stem cells occurs in the presence of low level of IFN-γ. Blood. 107:4817-4824, 2006. 63. Ponzio NM, Cutro S, Hu J, Marzouk A, Marshall J. CpG oligodeoxynucleotide-induced immunity prevents growth of germinal center derived B lymphoma cells. International Immunopharmacology. 6:2057-2068, 2006.


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64. Ponzio NM, Servatius R, Beck K, Marzouk A, Kreider T: Cytokine levels during pregnancy influence immunological profiles and neurobehavioral patterns of the offspring. Ann NY Acad Sci. 1107:118-128, 2007. 65. Castillo M, Trzaska K, Greco S, Ponzio NM, Rameshwar P: Immunostimulatory effects of mesenchymal stem cell-derived neurons: Implications for stem cell therapy in allogeneic transplantations. Clinical and Translational Science (Inaugural Issue). Volume1; Issue 1 (on-line access journal) Spring, 2008. 66. Upadhyay A, Ponzio NM, Pandey VN: Immunological response to peptide nucleic acid and its peptide conjugate targeted to transactivation response (TAR) region of HIV-1 RNA genome. Oligonucleotides. 18:1-8, 2008. 67. Speirs RS, Speirs EE, Ponzio NM: A role for eosinophils in adaptive humoral immunity. The Open Immunology Journal (an open access journal). 2:169-186, 2009. 68. Mandal M, Marzouk AC, Donnelly R, Ponzio, NM: Preferential development of TH17 cells in offspring of immunostimulated pregnant dams. J Reproductive Immunol. 87:97-100, 2010. (doi.org/10.1016/j.jri.2010.06.056) 69. Mandal M, Marzouk AC, Donnelly R, Ponzio NM: Maternal immune stimulation during pregnancy affects adaptive immunity in offspring to promote development of TH17 cells. Brain, Behavior, and Immunity. 25:863-871, 2011. (doi.org/10.1016/j.bbi.2010.09.011) 70. Fisher IB, McAlees JW, Sharp P, Kohm AP, Smith L, Erbe RS, Jarjoura D, Ponzio NM, Sanders VM: Epigenetic regulation of ß2-Adrenergic Receptor expression in murine primary Th1 and Th2 Cells. Brain, Behavior, and Immunity. 25:408-415, 2011. 71. Luistro LL, Rosinski JA, Hongjin B, Bishayee S, Rameshwar P, Ponzio NM, Ritland SR: Mechanistic implications in Trastuzumab acquired resistance using microarray expression profiling of a novel ovarian carcinoma model. Intl J Oncology. 41:639-651, 2012. (doi.org: 10.3892/ijo.2012.1463) 72. Banks WA, Niehoff ML, Ponzio NM, Erickson MA, Zalcman SS: Pharmacokinetics and modeling of immune cell trafficking: Quantifying differential influences of target tissues versus lymphocytes in SJL andl Lipopolysaccharide-treated mice. J Neuroinflammation. 9:231-245, 2012. (doi: 10.1186/1742-2094-9-231) 73. Pratt L, Ni L, Ponzio NM, Jonakait GM : Maternal immune activation promotes fetal microglial activation and increases choline acetyltransferase activity and cholinergic cell number in the fetal basal forebrain: implications for autism. Pediatric Research. 74:393-401, 2013. (doi: 10.1038/pr.2013.126)


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74. Mandal M, Elkabes S, Donnelly R, Zhang P, Davini D, David B, Ponzio NM: Maternal immune stimulation during pregnancy shapes the immunological phenotype of offspring. Brain, Behavior, and Immunity. 33:33-45, 2013. (doi.org/10.1016/j.bbi.2013.04.012) 75. Bliss SA, Sinha G, Sandiford OA, Williams L, Engelberth DJ, Guiro K, Isenalumhe LL, Greco SJ, Bryan M, Ponzio NM, Kumar R, Rameshwar P: Exosomes released from mesenchymal stem cells primed with breast cancer cells regulate tumor dormancy phenotype: Implications for a combined RNA therapeutics and chemotherapy. Cancer Research. 76(19); 5832–5844, 2016. (doi.org/10.1158/0008-5472.CAN-16-1092) 76. Walker, N; Liu, K; Mourad, Y; Buxhoeveden, M; Schoenberg, C; Eloy, J; Wilson, D; Brown, L; Botea, A; Chaudhry, F; Greco, S; Ponzio, NM; Koneru, B; Gubenko, Y; Rameshwar, P: Steroid-mediated decrease in blood mesenchymal stem cells in liver transplant could impact long-term recovery. Stem Cell Reviews. 13(5):644-658, 2017. (doi: 10.1007/s12015-017-9751-3) 77. Kaplan-Liss E, Lantz-Gefroh V, O’Connell C, Killebrew D, Ponzio NM, Bass E: Helping medical students learn to communicate with empathy and clarity. Academic Medicine. 93:440-443, 2018. (doi: 10.1097/ACM.0000000000002031) 78. Ponzio NM, Alder J, Nucci M, Dannenfelser D, Hilton H, Linardopoulos N, Lutz C: Learning science communication skills using improvisation, video recordings, and practice, practice, practice. Journal of Microbiology and Biology Education. 19(1):1-8, 2018. (doi:https://doi.org/10.1128/jmbe.v19il.1433)

79. Walker ND, Elias M, Guiro K, Bhatia R, Greco SJ, Bryan M, Gergues M, Sandiford OA, Ponzio NM, Leibovich SJ, Rameshwar P: Exosomes from differentially activated macrophages influence dormancy or resurgence of breast cancer cells within bone marrow stroma. Cell, Death and Disease (Nature Publishing Group journal), 10:59, 2019 (https://doi.org/10.1038/s41419-019-1304-z) Books, Monographs, Chapters, and Journal Series 1. Speirs RS, Speirs EE, Ponzio NM: Eosinophils in humoral and cell-mediated responses. In: Biology of the Lymphoid System, (Ed AA Gottlieb), pp. 51-73, CRC Press, Inc, Cleveland, 1974. 2. Ponzio NM, Chapman JM, Thorbecke GJ: Effect of antigen on the localization of immunologically specific B cells. In: The Reticuloendothelial System in Health and Disease. (eds H Friedman, M Escobar and S Reichard), pp. 65-76, Plenum Pub Corp, New York, 1976. 3. Lerman SP, Ponzio NM, Carswell EA, Thorbecke GJ: Properties of transplantable reticulum cell sarcomas in SJL/J mice. In: Immune Reactivity of Lymphocytes (eds MJ Feldman and A Globerson), pp. 691-697, Plenum Pub Corp, New York, 1976. 4. Ponzio NM, Matteoni LA, Sarley JM: Potentiation of allospecific cytotoxic T cell development by the autologous MLR. In: The Molecular Basis of Immune Cell Function (ed JG Kaplan) pp. 525-528, Elsevier/North Holland Biomedical Press, Amsterdam, 1979.

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5. Battisto JR, Ponzio NM: A review of autologous and isologous lymphocyte interactions and their immunological significance. Progress in Allergy 28:160-192, 1981. 6. Ponzio NM: Reticulum Cell Sarcomas (RCS) of SJL/mice: Pre-B cell lymphoma with apparent natural killer cell function. In: Natural Cell Mediated Immunity. (ed RB Herberman) Vol. 2, pp. 1153-1160. Academic Press, New York, 1982. 7. Ponzio NM, Brown P and Thorbecke GJ: Host-tumor interactions in the SJL lymphoma model. In: Int. Rev. Immunol. (ed, RG Lynch) Vol. 1, pp 273-301. Harwood Academic Publishers, Ann Arbor, MI, 1986. 8. Ponzio NM and Thorbecke GJ: Antigen-specific and non-specific patterns of B lymphocyte localization. In: Migration and homing of lymphoid cells. (ed A. Husband) Vol I, Chapter 6, pp 85-112. CRC Press, Boca Raton, FL, 1988. 9. Raska K and Ponzio NM: Cells and tissues of the immune system: a preview of the interactions to come. In: Basic and clinical immunology: Basic mechanisms and clinical consequences. (edited by L Sigal and Y Ron) McGraw Hill, Inc, New York. pp 15-36, 1994. 10. Ponzio NM, Zhang DJ, Tsiagbe VK and Thorbecke GJ: Influence of Mtv superantigen on B cell lymphoma development in SJL/J mice. In: Viral superantigens, K. Tomonari, ed. CRC Press, Inc, Boca Raton, FL, pp 219-231, 1997. 11. Tsiagbe VK, Zhang DJ, Erianne G Ponzio NM, Thorbecke GJ and Inghirami G: Germinal center derived lymphomas in humans and mice. In: The biology of germinal centers in lymphoid tissue, Chapter 5; GJ Thorbecke and VK Tsiagbe, eds. Landes Bioscience. Austin, TX. 1998. pp. 199-234. 12. Ponzio, NM and Thorbecke, GJ: Requirement for reverse immune surveillance for the growth of germinal center derived murine lymphomas. In: Seminars in Cancer Biology – Reverse Immune Surveillance, GJ Thorbecke and NM Ponzio, eds. Academic Press. 10:331-340, 2000. 13. Thorbecke GJ and Ponzio NM: Guest editors for special issue of Seminars in Cancer Biology (Volume 10 Number 5) devoted to the topic of Reverse Immune Surveillance. A total of 8 invited manuscripts were assembled for this issue. Academic Press. October, 2000. 14. Natelson BH, Haghighi MH, and Ponzio NM: A review of the evidence on the presence of immune dysfunction in chronic fatigue syndrome. Clinical and Diagnostic Laboratory Immunology. 9:747-752, 2002. 15. Ponzio NM, Mandal M, Elkabes S, Zhang P, Sadoshima S, Basak S, Zhai P, and Donnelly R: Pro-inflammatory phenotype induced by maternal immune stimulation during pregnancy. In: Recent Advances in Autism Spectrum Disorders - Volume I. Ed: Michael Fitzgerald. Pub: InTech, Rijeka, Croatia. pp113-141, 2013. (doi.org: 10.5772/53990)


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16. Morelli S, Kashani B, Goldsmith L, Mandal M, and Ponzio NM: The maternal immune system during pregnancy and its influence on fetal development. Research and Reports in Biology. Dove Medical Press, Ltd. Auckland, New Zealand. 6:1-19, 2015 Letters, Case Reports, Editorials, etc. 1. Tsiagbe VK, Zolla-Pazner S, Coico R, Ponzio, NM: In Memorium – G. Jeanette Thorbecke. J Immunol. 168:3695-3696, 2002. and Amer J Pathology. 160:1917-1920, 2002. 2. Ponzio, NM: Editorial: Communicating your science. International Journal of Translational Science. January 2017. http://www.riverpublishers.com/journal.php?j=IJTS/2016/1/jef ISSN: 2246-8765 (Online) 3. Ponzio, NM: Benchmarking Study of Leadership Training Programs for Undergraduate Medical Students: Rutgers Center for Organizational Development and Leadership; 2016. http://odl.rutgers.edu/research-development/#publications 4. Ponzio, NM: Communicating Science. Rutgers University Celebration of Scholarship 2017. March 28, 2017. https://www.libraries.rutgers.edu/sites/default/files/communications/celebration/RBHS%20catalog.pdf Abstracts and Presentations 1. Ponzio NM and Speirs RS: Model for immunological memory: Characterization of memory cells involved in cellular and humoral responses. 57th annual FASEB Meetings, Atlantic City, NJ, April, 1973.

2. Ponzio NM, Finke J and Battisto JR: Adult murine lymph node cells respond blastogenically to isogenic spleen cells. Ninth Leukocyte Culture Conference, Williamburg, VA, December, 1974. 3. Ponzio NM and Thorbecke GJ: Strong proliferative response, but lack of cytotoxic cell generation to syngeneic RCS tumor in lymphoid cells from normal and immune SJL mice. Tenth Leukocyte Culture Conference. Amsterdam, September, 1975. 4. Finke J, Ponzio NM and Battisto FR: Tropism of surface immunoglobulins may help determine isogeneic and allogeneic lymphocyte interactions. 10th Leukocyte Culture Conference, Amsterdam, September, 1975. 5. Ponzio NM and Thorbecke GJ: Effect of antigen on localization of immunologically specific B cells. 7th International Congress of the RES, Pamplona, Spain, September, 1975. 6. Ponzio NM and Thorbecke GJ: Relationship between induction of proliferation and cytotoxicity to syngeneic reticulum-cell sarcoma (RCS) in lymphoid cells from SJL mice. 60th Annual FASEB Meetings, Anaheim, CA, April, 1976.

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7. deKruyff RH, Ponzio NM and Thorbecke GJ: Influences on the localization of B cells in lymphoid tissue. 60th Annual FASEB Meetings, Anaheim, CA, April, 1976. 8. Ponzio NM and Thorbecke GJ: Effect of antigen on localization of immunologically specific B cells. 11th Leukocyte Culture Conference, Tuscon, Arizona, September, 1976. 9. Ponzio NM and Thorbecke GJ: Specific retention of B memory cells by antigen. 61st Annual FASEB Meeting, Chicago, Illinois, April, 1977. 10. Ponzio NM, Fitzgerald KL and Myers C: Natural killer (NK) cell activity in reticulum cell sarcomas (RCS) of SJL/J mice. 62nd Annual FASEB Meetings, Atlanta, GA, June, 1978. 11. Fyfe D, Ponzio NM and Finke J: Presence of foreign H-2 like antigenic specificities on reticulum-cell sarcoma cells syngeneic to SJL mice. American Assoc Cancer Res, 1978. 12. Butler G, Finke J, Ponzio NM and DelVillano B: Analysis of "target" cell surface alloantigens in syngeneic tumor cell lympholysis. Mid-West Autumn Immunology Conference, November, 1978. 13. Ponzio NM and Matteoni LA: Enhancement of the murine autologous mixed lymphocyte response (MLR) by polyethylene glycol (PEG). 63rd Annual FASEB Meetings, Dallas, Texas, April, 1979. 14. Fitzgerald KL and Ponzio NM: Reticulum cell sarcomas of SJL/J mice express natural killer (NK) cell function. 63rd Annual FASEB Meetings, Dallas, Texas, April, 1979. 15. Finke JH, Ponzio NM, Scott J and Orosz CG: Identification of antigens that stimulate helper factor production for cytotoxic T cell. 63rd Annual FASEB Meetings, Dallas, Texas, April, 1979. 16. Ponzio NM, Matteoni LA and Sarley JM: Potentiation of cytotoxic T cell development by the autologous mixed lymphocyte reaction. 13th International Leukocyte Culture Conference, Ottawa, Canada, May 1979. 17. Ponzio NM, Vilcek J and Thorbecke GJ: Constitutive production of T (Type II) interferon by a murine reticulum cell sarcoma. The New York Academy of Science Conference on Regulatory Functions of Interferons, October, 1979. 18. Fitzgerald KL and Ponzio NM: Reticulum-cell sarcomas (RCS) of SJL mice: a unique class of cytotoxic effectors with natural killer (NK) cell function. Fed Proc 39:900, 1980. (64th Annual FASEB Meetings, Anaheim, CA, April, 1980). 20. Medinieks MI, Schweppe JS and Ponzio NM: Cyclic AMP-dependent protein kinase activity in interferon and immunoglobulin secreting tumor cells. American Society for Cell Biology, November, 1980.


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21. Ponzio NM, Fitzgerald K and McMaster J: Lymphoma cells (RCS) of SJL/J mice exhibit natural killer (NK) cell function. Fed Proc 40:1092 (Abstract #4890). 65th Annual FASEB Meetings, Atlanta, GA, April, 1981. 22. Ponzio NM, Hayama T, Nagler C, Katz IR, Vilcek J and Thorbecke GJ: IR-gene restricted induction by lymph node T cells of lymphokine synthesis in irradiated lymphoma cells of SJL/J mice. J Cell Biochem Suppl 6:59, 1982 (Abstract #0168). 11th Annual ICN-UCLA Symposia, Squaw Valley, CA, March, 1982. 23. Ponzio NM, Hayama T, Nagler C, Katz IR, Vilcek J and Thorbecke GJ: IR-gene restricted induction by lymph node T cells of lymphokine synthesis by irradiated lymphoma cells of SJL/J mice. Fed Proc 41:319, 1982 (Abstract #298). 66th Annual FASEB Meetings, New Orleans, LA, April, 1982. 24. Brown PH, Cone R, Ponzio NM, Jones PP and Thorbecke GJ: Nature of T cell stimulating molecules on SJL/J lymphomas. Fed 42:1195, 1983 (Abstract #5292). 67th Annual FASEB Meetings, Chicago, IL, April, 1983. 25. Ponzio NM: Lymphoid abnormalities in SJL, NZB and other mice. Kroc Foundation Symposium: Murine models of demyelinative and other organ-specific diseases. Santa Ynez, CA, June, 1982. 26. Ponzio NM and Murdock A: Induction of natural killer cells by a syngeneic lymphoma in SJL/J mice. Fed Proc 42:677, 1983 (Abstract #2253). 67th Annual FASEB Meetings, Chicago, IL, April, 1983. 27. Kaur P, Pahwa S, Ponzio N, Desposito F, McDonald M, Singh R and Oleske J: Immune dysfunction in children with acquired immune deficiency syndrome. Amer Acad Allergy and Immunol Meeting in Chicago, IL, March, 1984. 28. Fine B, Ponzio N, Maher E and Walters T: Effect of dietary sodium deprivation on tumor growth. Amer Soc Clin Oncol Annual Meeting in Chicago, IL, March, 1984. 29. Ponzio NM, Murdock A and Taylor A: Natural killer (NK) cell activity in reticulum cell sarcomas (RCS) propagated in SJL/J mice possessing the beige mutation. Fed Proc 43:1753, 1984 (Abstract #1968). 68th Annual FASEB Meetings, St. Louis, MO, June, 1984. 30. Prince R, Ponzio NM and Strausser H: Tumor therapy by means of hyperthermia and a calcium channel blocker. Fed Proc 44:588, 1985 (Abstract #1040). 69th Annual FASEB Meetings, Anaheim, CA, April, 1985. 31. Brown PH, DeKruyff RH, Ponzio NM and Thorbecke GJ: Development of SJL T cell clones responsive to syngeneic lymphoma and activated B cells. Fed Proc 44:964, 1985 (Abstract #3237). 69th Annual FASEB Meetings, Anaheim, CA, April, 1985.


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32. Alisauskas RM and Ponzio NM: Monoclonal I-A antibody inhibits growth of I-A positive lymphomas in SJL/J mice. Fed Proc 44:1685, 1985 (Abstract #7454). 69th Annual FASEB Meetings, Anaheim, CA, April, 1985. 33. Ponzio NM: Host-tumor interactions in the SJL lymphoma model. Invited minisymposium presentation; 70th Annual FASEB Meetings, St. Louis, MO, April, 1986. 34. Alisauskas RM and Ponzio NM: T helper cell-specific monoclonal antibody inhibits growth of B cell lymphomas (RCS) in syngeneic SJL/J mice. Fed Proc 45: 269, 1986 (Abstract #667). 70th Annual FASEB Meetings, St. Louis, MO, April, 1986. 35. Alonso A and Ponzio NM: Production of antibodies against lymphocytes that respond to syngeneic reticulum cell sarcomas (RCS) of SJL/J mice. Fed Proc 45:717, 1986 (Abstract #3267). 70th Annual FASEB Meetings, St. Louis, MO, April, 1986. 36. Alisauskas RM and Ponzio NM: Mechanisms of growth inhibition of transplantable I-A+ lymphomas in SJL/J mice treated with anti-I-A monoclonal antibody (Abstract #3.15.47). 6th International Congress of Immunology, Toronto, Canada, July, 1986. 37. Erianne GS and Ponzio NM: Production of cloned hybrids of reticulum cell sarcoma (RCS) tumor cells possessing NK-like activity (Abstract #4.16.2). 6th International Congress of Immunology, Toronto, Canada, July, 1986. 38. Ponzio NM, Alisauskas RM and Alonso, A: Failure of lymphoma cells to grow progressively in the absence of a host immune response--Monoclonal antibody therapy to inhibit tumor reactive lymphocytes. NJ State Comm on Cancer Res "Workshop on Cancer Research in NJ, Woodbridge, NJ, November, 1986. 39. Alisauskas RM and Ponzio NM: T helper cell specific monoclonal antibody inhibits progressive growth of B cell lymphoma (RCS) in syngeneic SJL/J mice. Fed Proc 46:1512, 1987 (Abstract #6977). 71st Annual FASEB meeting, Washington, DC, March, 1987. 40. Alonso A and Ponzio NM: Production of autoantibodies against lymphocytes that respond to syngeneic lymphomas in SJL mice. Fed Proc 46:1506, 1987 (Abstract #6942). 71st Annual FASEB meeting, Washington, DC, March, 1987. 41. Lasky JL, Erianne GS, Ponzio NM and Thorbecke GJ: Characterization and growth factor requirements of SJL lymphoma: development of an in vitro reticulum cell sarcoma (RCS) cell line (cRCS-X). Fed Proc 46:1506, 1987 (Abstract #6941). 71st Annual FASEB meeting, Washington, DC, March, 1987. 42. Alisauskas RM and Ponzio NM: Treatment of reticulum cell sarcomas (RCS) in SJL/J mice with anti-I-As monoclonal antibodies induces antigenic modulation and promotes tumor dormancy. Proc Amer Assoc Cancer Res 28:392, 1987 (Abstract #1556). 78th Annual AACR meeting, Atlanta, GA, 1987.


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43. Lin Tao-Zhen, Alisauskas RM and Ponzio, NM: Natural killer (NK) cell activity in syngeneic transplantable B cell lymphomas (RCS) propagated in SJL/J "beige" mice. Proc Amer Assoc Cancer Res 28:346, 1987 (Abstract #1372). 78th Annual AACR meeting, Atlanta, GA, May, 1987. 44. Erianne GE, Lasky J, Thorbecke GJ and Ponzio, NM: Production of in vitro cell lines from spontaneous reticulum cell sarcomas (RCS) of SJL/J mice. Proc Amer Assoc Cancer Res 28:46, 1987 (Abstract #181). 78th Annual AACR meeting, Atlanta, GA, May, 1987. 45. Alonso A and Ponzio NM: Lymphocyte responses to syngeneic antigens: autoantibodies to syngeneic lymphoma-responsive lymphocytes. FASEB Journal 2:A1840, 1988 (Abstract #8967). 72nd Annual FASEB meetings, Las Vegas, NV, May, 1988. 46. Lin Tao Zhen and Ponzio NM: Syngeneic lymphoma cells provide a unique stimulus to natural killer (NK) cells in genetically low-NK SJL/J mice. FASEB Journal 2:A459, 1988 (Abstract #0950). 72nd Annual FASEB meetings, Las Vegas, NV, May, 1988. 47. Alisauskas RM, Hollberg CA, Hadala JT and Ponzio NM: Influence of anti-L3T4a monoclonal antibody treatment on growth potential and metastatic properties of follicular center cell lymphomas of SJL/J mice. Proc Amer Assoc Cancer Res 29:417, 1988 (Abstract #1659). 79th Annual AACR meeting, New Orleans, LA, May, 1988. 48. Buckley MJ, Jacobson EB and Ponzio NM: Maintenance of murine immunoglobulin (Ig) allotype suppression is T helper (TH) cell independent. FASEB Journal, 1989 (Abstract #). 73rd Annual FASEB meetings, New Orleans, LA, March, 1989. 49. Alonso A and Ponzio NM: Autoantibody response of SJL/J mice against syngeneic tumor activated blast (TAB) cells: characterization of the autoantigen. FASEB Journal, 1989 (Abstract #). 73rd Annual FASEB meetings, New Orleans, LA. March, 1989. 50. Alisauskas RM, Hollberg C and Ponzio NM: Short-term treatment with anti-L3T4a monoclonal antibody inhibits progressive in vivo growth of B cell lymphomas and promotes long-term survival of tumor cell injected SJL/J mice. Proc Amer Assoc Cancer Res, 1989 (Abstract #). 80th Annual AACR meeting, San Francisco, CA. May, 1989. 51. Buckley MJ, Jacobson EB and Ponzio NM: Splenic Lyt-2+ cells mediate allotype suppression in (BALB/c x SJL/J) mice by a non-cytotoxic mechanism. FASEB Journal. 4:A1879, 1990 (Abstract #1083). 74th Annual FASEB meetings, New Orleans, LA. June, 1990. 52. Ponzio NM, Quigley G, Friedman C and Yauch R. Influence of anti-CD4 monoclonal antibody treatment on development of primary B cell lymphomas in SJL/J mice. FASEB Journal. 4:A1716, 1990 (Abstract #127). 74th Annual FASEB meetings, New Orleans, LA. June, 1990.


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53. Wajchman H, Yauch R and Ponzio NM: Unique membrane determinants expressed on tumor activated blast (TAB) T cells. FASEB Journal 5:A1771, 1991 (Abstract #7787). 75th Annual FASEB meetings, Atlanta, GA. April, 1991. 54. Ponzio NM, Lin T-Z and Quigley G: Dormancy of B cell lymphomas after treatment with anti-CD4 monoclonal antibody. FASEB Journal 5:A1712, 1991 (Abstract #8133). 75th Annual FASEB meetings, Atlanta, GA. April, 1991. 55. Wajchman, HJ and Ponzio NM: Detection of unique membrane determinants on tumor activated T cells. J Immunol. 150:58A, 1993. (Abstract #317). Annual AAI/CIS meeting, Denver, CO. May, 1993. 56. Weller AH, Rosenberg NL and Ponzio NM: Depletion of CD4-positive cells exacerbates myositis in SJL/J mice. J Immunol. 152:3229, 1994. (Abstract #115) 9th Annual Conference on Clinical Immunology sponsored by the Clinical Immunology Society; Anaheim, CA; April, 1994. 57. Wajchman J, Klein A, Park J and Ponzio NM: Interleukin-12 promotes development of cytotoxicity against a syngeneic B cell lymphoma in SJL/J mice. FASEB J. 9:A222, 1995. (Abstract #1290). Experimental Biology 95 meetings, Atlanta, GA. April, 1995. 58. Wajchman HJ and Ponzio NM: Emergence of CD4+CD8+ (Double Positive) T cells after stimulation with syngeneic B lymphoma cells in SJL/J mice. FASEB J. 9:A800, 1995. (Abstract #4633). Experimental Biology 95 meetings. Atlanta GA, April, 1995. 59. Weller AH and Ponzio NM: Depletion of either CD4+ or CD8+ T cells accelerates the development of spontaneous myositis in SJL/J mice. FASEB J. 9:A526, 1995. (Abstract #3048). Experimental Biology 95 meetings, Atlanta, GA. April, 1995. 60. Wajchman JR, Klein AJP, Parks J and Ponzio NM: Cytokine modulation of cytotoxic effector cells induced by syngeneic B cell lymphomas (RCS) of SJL/J mice. Annual Retreat on Cancer Research in New Jersey. May 31, 1996. Princeton, NJ. 61. Wajchman HJ and Ponzio NM: Contribution of Lactate Dehydrogenase ElevatingVirus (LDV) to the host Immune response to a syngeneic B cell lymphoma in SJL/J mice. Annual Retreat on Cancer Research in New Jersey. May 31, 1996. Princeton, NJ. 62. Rameshwar P, Batarseh H, Smith I and Ponzio NM: Use of Human Umbilical Cord Blood for adoptive therapy. Annual Retreat on Cancer Research in New Jersey. May 31, 1996. Princeton, NJ. 63. Wajchman JR, Klein AJP, Parks J and Ponzio NM: Effect of IL-12 on the cytotoxicity induced by syngeneic B cell lymphomas (RCS) of SJL/J mice. FASEB J. 10:A1348, 1996. (Abstract #2013) Presented at the ASBMB/ASIP/AAI Joint Meeting; New Orleans, LA; June, 1996. 64. Wajchman HJ and Ponzio NM: Detection of tumor activated blast (TAB) antigen on an in vitro SJL/J B cell lymphoma line (cRCS-XHW) and its relationship to viral antigens. FASEB J.


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10:A1466. (Abstract #2689) Presented at the ASBMB/ASIP/AAI Joint Meeting; New Orleans, LA; June, 1996. 65. Tsiagbe VK, Erianne G, Charytan D, Simmons WJ, Miller R, Linsley PS, Podack ER, Noelle RJ, Thorbecke GJ, Ponzio NM: Role of co-stimulation in Mtv29 superantigen induced Vb16 T cell responses to SJL lymphomas. J Allergy & Clin Immunol. 99:S40, 1997. (Abstract #166) Presented at the AAAAI/AAI/CIS Joint Meeting; San Francisco, CA; February 21-26, 1997. 66. Rameshwar P, Smith I, Ponzio NM: Use of human umbilical cord blood as an adjuvant therapy for hematopoietic deficiency. Worcester Translational Research Conference on Bone Marrow Transplantation for the Treatment of Autoimmune Disease. Worcester, MA; November, 1997. 67. Erianne GS, Zhang DJ, Thorbecke GJ, Tsiagbe VK, Ponzio NM: Natural killer cells influence growth of B cell lymphomas in C57L/J mice. FASEB J.12:A905, 1998. (Abstract #5240) Presented at the FASEB Experimental Biology ‘98 meetings; San Francisco, CA; April, 1998. 68. Erianne G, Wajchman J and Ponzio NM. Influence of NK and T helper cells on development and growth of B cell lymphomas of C57L mice. Cancer Research. 40:659, 1999. (Abstract #4348) AACR Annual Meeting; April 10-14, 1999; Philadelphia, PA. 69. Ponzio NM, Erianne G, Simmons WJ, Tsiagbe VK, Sen N, Zhang DJ, Beamer WG and Thorbecke, GJ. Mammary tumor virus (Mtv) encoded superantigen (vSAG) expression as a common mechanism in several mouse strains for B cell lymphomas to elicit growth-promoting host T cell help. (Abstract # ) Exp. Biology Meetings; April 17-21, 1999; Washington, DC. 70. Rameshwar P and Ponzio NM. Use of human umbilical cord blood as an adjuvant therapy for hematopoietic deficiency. Clin Immunol. 90:480, 1999. (Abstract #217) Clinical Immunology Society Meeting; April 15-17, 1999; Washington, DC 71. Simmons WJ, Sen N, Erianne G, Zhang DJ, Huang C, Thomas RM, Tsiagbe VK, Ponzio NM Jaeggli S, and Thorbecke GJ: Env-initiated transcripts encoding superantigens (vSAg29 and vSAg7) in B cell lymphomas and their role in lymphomagenesis. FASEB Journal. 14:A1014, 2000. (Abstract # 56.21) Immunology 2000; Amer Assoc Immunol & Clin Immunol Soc Mtgs; May 12-16, 2000; Seattle, WA. 72. Simmons WJ, Haleem K, Chiarle R, Inghirami G, Tsiagbe VK, Beamer W, Thorbecke GJ, and Ponzio NM. Multi-parameter analysis of SWxJ recombinant inbred strains suggest common cross-strain properties of spontaneous germinal center B cell lymphomagenesis. . FASEB Journal. 15:A1180, 2001. (Abstract # 925.1) Experimental Biology 2001; Annual Meetings of Amer Assoc Immunology & Amer Soc for Invest Pathology; March 31 – April 4, 2001; Orlando, FL. 73. Simmons WJ, Koneru M, Wajchman J, and Ponzio NM: IL-12-induced effector cells inhibit growth of syngeneic B cell lymphomas of SJL/J mice. . FASEB Journal. 15:A659, 2001. (Abstract # 522.3) Experimental Biology 2001; Annual Meetings of Amer Assoc Immunology & Amer Soc for Invest Pathology; March 31 – April 4, 2001; Orlando, FL.


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74. Simmons WJ, Wajchman J, Koneru M, Bai M, and Ponzio NM: Induction of IFN-γ in the absence of IL-12 is insufficient for activation of NK cells and the development of tumor specific CD8+ T cells against murine B cell lympomas of SJL/J mice. (Abstract # 073) Annual Retreat on Cancer Research in New Jersey. April 25, 2001. Princeton, NJ. 75. Simmons WJ, Haleem K, Chiarle R, Inghirami G, Tsiagbe VK, Beamer W, Thorbecke GJ, and Ponzio NM: Shared cellular and molecular traits of spontaneous germinal center B cell lymphomas from different mouse strains suggests a common genetic etiology. (Abstract # 109) Annual Retreat on Cancer Research in New Jersey. April 25, 2001. Princeton, NJ. 76. Simmons WJ, Koneru M, and Ponzio NM: SJL lymphoma-specific Th1 cells facilitate the development of tumor-specific cytotoxic effector cells. FASEB Journal. 2002. (Abstract # 6931) Experimental Biology 2002; Annual Meetings of Amer Assoc Immunology & Amer Soc for Invest Pathology; April 20 - 24, 2002; New Orleans, LA. 77. Simmons WJ, Koneru M, and Ponzio NM: IL-12 polarized Th1 cells promote development of SJL B cell lymphoma-specific cytotoxic effector cells. Cancer Research. 43:1112, 2002. (Abstract # 5510). 93rd Annual Meeting of the American Association for Cancer Research; April 6 - 10, 2002. San Francisco, CA. 78. Simmons WJ, Koneru M, and Ponzio NM: Cancer immunotherapy with syngneneic IL-12 polarized Th1, but not Th2, cells promotes development of lymphoma-specific cytotoxic effector cells. (Abstract # C-1) Annual Retreat on Cancer Research in New Jersey. April 24, 2002. Princeton, NJ. 79. Potian JA, Ahmeti E, Ramkissoon S, Harrison JS, Ponzio NM, Rameshwar P: Veto-like activity of mesenchymal stem cells (MSC) and the concentration of interferon-gamma in the microenvironment are important parameters to offset the allogeneic effects of MSC. 44th Annual Meeting of the American Society of Hematology. (Abstract # 553706) December 6-10, 2002. Philadelphia, PA 80. Simmons WJ, Koneru M, Mohindru M, Thomas R, Cutro S, Singh P, Inghirami G, Coyle A, Kim BS, Ponzio NM: In Vivo Localization and Efficacy of Adoptively Transferred Tim-3 Positive Tumor Specific TH1 Cell Clones. (Abstract # 2870). Cancer Research 44:655, 2003. 94th Annual Meeting of the American Association for Cancer Research; April 5 - 9, 2003. Toronto, Canada. (Note: The Toronto meeting was cancelled due to concerns about SARS, and rescheduled for June 11 - 14, 2003 in Washington, DC. Revised Abstract #2871) 81. Simmons WJ, Koneru M, Mohindru M, Thomas R, Cutro S, Singh P, DeKruyff RH, Inghirami G, Coyle A, Kim BS, Ponzio NM: Adoptively Transferred Tim-3+ T-bet+ Tumor Specific TH1 Cell Clones Co-localize With and Inhibit Development and Growth of B Cell Lymphomas. (Abstract # 2778) Annual Meeting of American Association of Immunologists. May 6 - 10, 2003. Denver, CO.


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82. Simmons WJ, Singh P, Cutro S, and Ponzio NM: Tumor specific TH1 cells inhibit the development and growth of syngeneic B lymphoma cells. (Abstract # C-1) Annual Retreat on Cancer Research in New Jersey. June 11, 2003. Princeton, NJ. 83. Luistro LL, Tovar C, Bishayee S, Rameshwar P, Ponzio NM, and Ritland SR. Development and characterization of a pre-clinical model of ovarian carcinoma to investigate mechanisms of resistance to the anti-HER2/neu antibody Herceptin™. . (Abstract # 1205). Cancer Research , 2004. 95th Annual Meeting of the American Association for Cancer Research; April , 2004. Orlando, FL. 84. Zalcman S, and Ponzio NM: Maternal exposure to Interleukin-2 induces long lasting behavior inducing effects in offspring. International Meeting for Autism Research (IMFAR) May 2004. Sacramento, CA. 85. Zalcman, Steven S., Alba Rossi-George, Jessica Hu, Mark D. Bobbin, Janet Worobiej, and Nicholas M. Ponzio. Maternal exposure to interleukin-2 induces long-lasting increases in behavioral and neuronal responses to novelty and psychostimulant challenge in offspring. Society for Neuroscience. October 23-27, 2004. San Diego, CA. Program No. 806.16. 2004 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2004. Online. 86. Chan, JL, Harrison, JS, Ponzio, NM, and Rameshwar, P: Mesenchymal stem cells exhibit antigen presenting and phagocytic properties: Implications to bone marrow failure during inflammation. 46th Annual Meeting of the American Society of Hematology. (Abstract # 553695) December, 2004. San Diego, CA 87. Ponzio, NM, Simmons WJ, Cutro S, Singh P, Inghirami G, Coyle A, Sanders V. Inhibition of development and growth of B cell lymphomas by adoptive transfer of Tim-3+ tumor-specific TH1 cells. (Abstract # 817.12). Experimental Biology 2005 - Annual Meeting of American Association of Immunologists. March 31 - April 5, 2005. San Diego, CA. 88. Luistro, Leopoldo L., James A. Rosinski, Hongjin Bian, Steve R. Ritland, and Nicholas M. Ponzio. Herceptin-Refractory Ovarian Carcinoma Cells Differentially Express Genes Involved in Angiogenesis, Invasion, and Metastasis. (Abstract # 5085). 96th Annual Meeting of the American Association for Cancer Research; April 16-20, 2005. Anaheim, CA. 89. Luistro, Leopoldo L., James A. Rosinski, Hongjin Bian, Nicholas M. Ponzio, and Steve R. Ritland. A preclinical model of ovarian carcinoma resistant to Herceptin differentially expresses genes involved in angiogenesis, invasion and metastasis. (Abstract # P-49) Annual Retreat on Cancer Research in New Jersey. April 27, 2005. Princeton, NJ. 90. Parul Singh, Jessica Hu, and Nicholas M. Ponzio. Characterization of tumor responsive CD4+ and CD8+ T cells in the presence of Interleukin-12. (Abstract # P-75) Annual Retreat on Cancer Research in New Jersey. April 27, 2005. Princeton, NJ.


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91. Singh P, Cutro S, Li Y, Gasinu S, Tsiagbe VK, Ponzio NM. Characterization of tumor-responsive CD4+ and CD8+ T cells under the influence of Interleukin-12. (Abstract #06-AB-782) 96th Annual Meeting of the American Association for Cancer Research; April 1-5, 2006. Washington, DC 92. Li Y, Gasinu S, Singh P, Cutro S, Ponzio NM, Tsiagbe VK. CD8+ T cells responding to endogenous retroviral superantigen vSAg29 transcribing lymphomas require Interleukin-12 for cytotoxicity against tumor. (Abstract #141.11) Annual Meeting of American Association of Immunologists. May 12 - 16, 2006. Boston, MA. 93. Ponzio NM, Cutro S, Hu J, Marzouk A, Marshall JD: CpG oligodeoxynucleotide-induced immunity prevents growth of germinal center-derived B lymphoma cells. (Late Breaking Abstract #79) Annual Meeting of American Association of Immunologists. May 12 - 16, 2006. Boston, MA. 94. Ponzio NM, Servatius RJ, Beck KD, Marzouk AC, Kreider TR: Cytokine levels during pregnancy influence immunological profiles and neurobehavioral patterns of the offspring – a prenatal model of autism. 5th International Congress on Autoimmunity (Nov 29 – Dec 3, 2006) Sorrento, Italy. 95. Jiao X, Zaccone EJ, Ponzio NM, Beck KD, Servatius RJ: Cytokine administration to pregnant mouse dams: Toward an animal model of autism. Pavlovian Society Annual Meeting September 14-16, 2006. Philadelphia, PA. 96. Li Y, Ponzio NM, Tsiagbe VK: Endogenous retroviral superantigen vSAg29 subverts Treg inhibition of proliferation of responsive CD4 T cells via deregulated cytokine production. Experimental Biology 2008; American Society for Investigative Pathology; April 5-9, 2008. SanDiego, CA. 97. Ponzio NM, Jonakait GM, Mandal M, Pratt L, Marzouk AC, Yehia G: Immunostimulation during pregnancy alters the development of T helper subsets in mother and offspring in a prenatal model of autism. 6th International Congress on Autoimmunity. Porto, Portugal. September 10-14, 2008. 98. Mandal M, Marzouk AC, Yehia G, Ponzio, NM: Immunostimulation during pregnancy alters development of T helper cell subsets of offspring in prenatal models of autism. Annual meeting of the Society for Neuroscience. Washington, DC. November 15-19, 2008. 99. Mandal M, Marzouk A, Donnelly R, Yehia G, and Ponzio, NM. Maternal immune activation during pregnancy alters development of T helper cell subsets of offspring in prenatal models of autism. 8th Annual International Meeting for Autism Research. Chicago, IL. May 6-8, 2009. 100. Ramanathan M, Ponzio NM and Fernandes H: Maternal cytokine regulation in the pathogenesis of autism. 5th Asian Pacific Congress in Maternal Fetal Medicine. November 2009; Hong Kong, China.


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101. Pratt L, Ponzio NM, Ni L, Sheng I, and Jonakait GM: Fetal microglia become activated following maternal immune challenge. 9th Annual International Meeting for Autism Research. Philadelphia, PA. May 20-22, 2010. 102. Mandal M, Marzouk AC, Donnelly R, Ponzio NM: Preferential differentiation of TH17 cells in offspring of immune-activated dams in a prenatal mouse model of autism. 9th Annual International Meeting for Autism Research. Philadelphia, PA. May 20-22, 2010. Also presented at the annual meeting of the Psychoneuroimmunology Research Society. Dublin, Ireland. June 2-5, 2010. 103. Ramanathan M, Ponzio NM, Limson F, Shah S, and Fernandes H: Maternal cytokine regulation in the pathogenesis of autism. 9th Annual International Meeting for Autism Research. Philadelphia, PA. May 20-22, 2010. 104. Agley AL, Jiao X, Beck KD, Pang KCH, Ponzio NM, Servatius RJ: A diathesis approach to modeling autism in rats: Interaction of immune activation in dams of either normal or inhibited temperament. Society for Neuroscience Annual Meeting satellite event: Emerging neuroscience of autism spectrum disorders. San Diego, CA. November 11-12, 2010. 105. Mandal M, Marzouk AC, Donnelly R, Ponzio NM: In utero cytokine exposure influences postnatal development of T helper cells. 10th Annual International Meeting for Autism Research. San Diego, CA. May 12-14, 2011. 106. Mandal M, Basak S, Marzouk AC, Donnelly R, Ponzio NM: Pre-natal cytokine exposure influences postnatal development of T helper cells. 18th Annual meeting of the Psychoneuroimmunology Research Society. Chicago, IL. June 8-11, 2011. 107. Mandal M, Donnelly R, Elkabes S, Ponzio NM: Maternal immune stimulation during pregnancy facilitates prenatal immuno-developmental changes leading to a pro-inflammatory phenotype in offspring. 11th Annual International Meeting for Autism Research (IMFAR). Toronto, Ontario. May 17-19, 2012. 108. Mandal M, Donnelly R, Elkabes S, Ponzio NM: Fetal programming of the immune system in a prenatal model of neurodevelopmental disorders. New York Academy of Sciences meeting on Fetal Programming and Environmental Exposures. June 11-12, 2012 109. Mandal M, Donnelly R, Elkabes S, Zhang P, PonzioNM: Maternal Cytokine Regulation in the Etiology/Pathogenesis of Autism. 12th Annual International Meeting for Autism Research (IMFAR). Donostia/San Sebastian, Spain. May 2-4, 2013. 110. Ponzio NM, Mandal M, Zhang P, Elkabes S, Donnelly R: Maternal immune stimulation during pregnancy promotes development of a pro-inflammatory phenotype in offspring. Society for Leukocyte Biology. Newport, RI. October 20-22, 2013.


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111. Ponzio NM and Kaplan SL: Re-defining clinical roles across a spectrum of health care settings. Invited presentation at the annual meeting of SENCER (Science Education for New Civil Engagements and Responsibilities). Asheville, NC, July 31 - August 4, 2014. 112. Sherman LS, Ponzio NM, Rameshwar P: Understanding the effects of an inflammatory milieu on the development of mesenchymal stem cells: implication for treating dormant cancer stem cells. Annual meeting of the American Association of Immunologists. Seattle, WA May 13-17, 2016.

113. Sinha G, Ghazarayan S, Sandiford OA, Ponzio NM, Rameshwar P: N-cadherin-Connexin 43 Axis in Breast Cancer Stem Cell: Implication for Dormancy in Bone Marrow 2016 Cancer Research Retreat; May 26, 2016; New Brunswick, NJ 114. Sherman LS, Sandiford OA, Ponzio NM, Rameshwar P: Understanding the effects of an inflammatory milieu on the development of mesenchymal stem cells: implication for treating dormant cancer stem cells. 2016 Cancer Research Retreat; May 26, 2016; New Brunswick, NJ.

115. Ponzio NM, et al. Scientist to storyteller – Communicating your Public Health science; 22nd Annual Public Health Symposium: Communicating Science of Public Health – A critical skill in challenging times; Piscataway, NJ; April 3, 2017. https://ophp.sph.rutgers.edu/phs2017/phs2017/Main.html

116. Ponzio, NM: Polishing your communication style: Panelist; 8th Annual Rutgers Postdoctoral Symposium; Re-defining the postdoctoral experience – new training for new careers; Robert Wood Johnson Medical School; Piscataway, NJ; April 28, 2017. https://rutgerspda.wordpress.com/events/postdoc-symposium-2017/

117. Walker ND, Elias M, Greco SJ, Ponzio NM, Rameshwar P: Crosstalk between mesenchymal stem cells and macrophages during breast cancer dormancy. Annual Retreat on Cancer Research in New Jersey; May 25, 2017. 118. Sherman LS, Ponzio NM, Rameshwar P: Understanding the effects of an inflammatory milieu on the development of mesenchymal stem cells: implication for treating inflammatory diseases; 6th Annual Research Retreat, Track in Infection, Immunity, and Inflammation; New Brunswick, NJ; June 30, 2017. 119. Sinha G, Ayer S, Ferrer A, Bibber B, Greco S, Sandiford O, Seth A, Ponzio NM, Rameshwar P: Cancer Stem Cell dormancy via N-cadherin/ Connexin43 Axis in Bone marrow. New Jersey Commission on Cancer Research Annual Meeting; May 24, 2018. 120. Sinha G, Ayer S, Ferrer A, Bibber B, Greco S, Sandiford O, Seth A, Ponzio NM, Rameshwar P: Cancer Stem Cell dormancy via N-cadherin/ Connexin43 Axis in Bone marrow. Cancer Stem Cell Conference; Cleveland, OH; August 6-8, 2018. 121. Ponzio NM, Badheka D: Teaching the Business of Science – Molecules to Medicines 2018 Regional Academic Drug Discovery Conference; Piscataway, NJ; November 15, 2018.

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