CURRICULUM VITAE Rinus Pretorius MBChB, FRCA, MSc(Dip)

PERSONAL DETAILS Name: Address: Cardiff CF5 2LQ Telephone: E-Mail: Date of birth: GMC Registration Nationality: Languages: Tel 029 20562655 Rinus5@hotmail.com 28 March 1968 4074784 Full registration May 1994 European Community (Dutch) Permanent right of residence English, Afrikaans, Dutch, Zulu (medical knowledge) Rinus David Pretorius 2 The Avenue Llandaff

SECONDARY EDUCATION 1981 - 1985 Matric Three Rivers High School Vereeniging, Republic of South Africa

HIGHER EDUCATION 1986 - 1991 MB ChB University of the Orange Free State Republic of South Africa

POST GRADUATE March 1995 June 1999 May 2001 United States Medical Examination F.R.C.A. M.Sc (Dip) in Clinical Science

APPOINTMENTS

CURRENT APPOINTMENT:

Aug 2004 - Present

Consultant Anaesthetist York Hospital York

PREVIOUS APPOINTMENTS:

Dec 2003-Aug 2004

SPR Anaesthesia Dept of Anaesthetics UHW Cardiff

Aug 2002 - Nov 2003

Advanced Trainee Intensive Care Medicine Dept of Anaesthetics and Intensive Care UHW Cardiff SPR Anaesthesia Dept of Anaesthetics Royal Gwent Hospital Newport SPR Anaesthesia Department of Anaesthetics UHW Cardiff

July 2001 -July 2002

August 2000 -July 2001

Feb 2000 - July 2000

SPR Anaesthesia Royal Gwent Hospital Dept of Anaesthetics Newport Registrar (LAT) Department of Anaesthetics Taunton and Somerset Hospital Taunton Registrar (LAS) Department of Anaesthesia & Intensive Care Derriford Hospital, Plymouth

April 1999 - Jan 2000

Jan 1999 - Mar 1999

Sept 1998 - Jan 1999

Registrar (LAS) Department of Anaesthetics & Intensive Care Royal Cornwall Hospitals Trust Treliske Hospital, Truro Registrar Critical Care Medicine Flinders Medical Centre Adelaide, South Australia Senior House Officer Anaesthesia and Intensive Care Torbay Hospital, Devon

Aug 1997- Aug 1998:

Aug 1996 - Jun 1997:

Nov 1995 - Jul 1996:

Senior House Officer Anaesthesia and Intensive Care Derriford Hospital, Plymouth Devon Senior House Officer Department of Anaesthetics Royal Devon and Exeter Hospital Exeter Senior House Officer Anaesthesia and Intensive Care Nqwelezana Hospital Natal, Republic of South Africa Senior House Officer General Medicine Nqwelezana Hospital Natal, Republic of South Africa Senior House Officer Accident and Emergency Nqwelezana Hospital Natal, Republic of South Africa House Officer Nqwelezana Hospital Natal, Republic of South Africa

Oct 1994 - Oct 1995:

Mar 1994 - Aug 1994:

Aug 1993 - Feb 1994:

Feb 1993 - Jul 1993:

Jan 1992 - Jan 1993:

Critical Care ExperienceConsultant Anaesthetist, York Hospital Advanced trainee ITU, UHW Cardiff Registrar in critical care medicine, Adelaide, South Austalia Registrar in Paediatric ITU, UHW Cardiff Intermediate training: SPR level: UHW Cardiff Royal Gwent, Newport SHO level: Derriford Plymouth Treliske, Truro 5 Years 12 months 12 months 3 months 6 months 6 months 3 months 3 months

I am currently employed as a Consultant Anaesthetist with sessional responsibilities in Intensive Care. As a Trainee I have a cumulative experience of over 3 years in critical care, which includes Paediatrics and experience abroad. My final year was spent as the advanced trainee, where I joined the consultant rota, leading ward rounds and overseeing the clinical duties of junior staff. I am familiar with the use of the latest technologies including High Flow Oscillatory Ventilation and PiCCO monitoring. In my most recent post as advanced trainee, I have become familiar with the use of activated protein-c as part of the treatment in the early stages of sepsis. I have been extensively involved in research including multicentre trials and regular attendance of research meetings. My research projects include prokinetics in the critically ill and the use of splancnic blood flow on admission as an indicator of response to resuscitation. I have extensive experience in the transport and retrieval of the critically ill patients whilst in Australia and in stabilization and retrieval of Paediatric patients. My interests include nutrition in the critically ill and non-invasive ventilation. I will complete my training with a CCST in anaesthesia and intensive care medicine.

Anaesthetic ExperienceMy anaesthetic career in the U.K. was started in the South West, although I had some experience in South Africa. I joined a 5-year training program in South Wales in 2000. I have a special interest in anaesthesia for the critically ill and multi-trauma patients, as well as the patient with the difficult airway. My experience in South Africa included working in a peripheral hospital in a third world environment, with limited resources. I was extensively involved with teaching of nursing staff involved with anaesthetics. During my time as a SPR, I completed a M.Sc(Dip) in clinical science, which enabled me to be extensively involved in teaching of medical students as well as on other M.Sc courses.

RESEARCH Current 2002-2003 I am the chief collaborator for the FIRE (Fungal Infection Risk Evaluation) and SWINEFLU studies at York Hospital Enteral feeding in the critically ill. I looked at the effects of prokinetic agents on the absorption of feeding in critically ill patients using the Paracetamol absorption test I researched the effects of splancnic blood flow on morbidity and mortality on admission to ITU using indocyanine green I was involved in the recruitment of patients for the ADDRESS multicentre trial into Activated Protein-C as well as recruitment for the multicentre Surfactant trial. 2002 1991 MSc module in research statistics and trial designs Final year project medical student: Effects of Magnesium on PIH and essential hypertension in pregnancy

AUDIT 1997 2000 2001 Whilst in Australia I looked at the complication rate of central lines on the ward, which led to a centralized service. Pre-operative ECHO requests led to a standardized protocol for requests whilst I was in Newport. I looked at the most common reasons why patient were re-admitted to ITU following discharge to HDU. This contributed to the eventual amalgamation of ITU and HDU. I conducted a major audit into the management of severe Pancreatitis on ITU, which led to a consensus on use of prophylactic antibiotics and a standardized feeding regimen. Welsh Intensive care society presentation 2002 Why do patients die after ITU discharge? I investigated the possibility of adverse events after discharge that could have led to death on the ward. Welsh Intensive care society presentation

PRESENTATIONS Severe pancreatitis: An Audit of the management on ITU R Pretorius, S Grundler, G Findlay WICS meeting 2001 Why patients die after leaving ITU R Pretorius, G Findlay, M Smithies WICS meeting 2003 Another cardiac arrest Grand round presentation University Hospital Wales 2003 Welsh Society of Anaesthetists 2004 Airway compromise after Carotid endarterectomy R.Sivasubramanian, RD Pretorius I Hodzovic British Society of Vascular Anaesthesia meeting 2003 Welsh Society of Anaesthetists 2004 PUBLICATIONS Review articles 1. Bronchoscopies and other thorascopic procedures of the thorax. R D Pretorius, R S Vaughan Paper submitted for publication to BJA Feb 2004 Abstracts 1. Why do patients die after ITU? R D Pretorius, G P Findlay, M N Smithies Welsh Intensive Care Society 2001 2. Audit of the management of severe pancreatitis on ITU. R D Pretorius, S Grundler Welsh Intensive Care Society 2003 3. Prokinetics in the critically ill. R D Pretorius, G P Findlay, R Roberts, C Weaver Critical Care Forum, Oct 2003 4. Splancnic bloodflow on admission as an indicator of prognoses. R D Pretorius, G P Findlay Critical Care Forum, Oct 2003

5. Airway obstruction following CEA. S Ramanathan, R D Pretorius, I Hodzovic Vascular Anaesthesia Society of Great Britain and Ireland, Liverpool 2003 6. Management of Central Venous catheters in ICU. R Pretorius BMJ International Coference on Quality and Safety,Berlin, May 2009 7. . Management of Central Venous catheters in ICU. R Pretorius National Patient Safety Conference, Birmingham, July 2009

Letters 1. Who should be doing central lines? R D Pretorius BMJ Rapid response letters, Feb 2003 2. Survival of cardiac arrest R D Pretorius, M S Stacey Submitted to BMJ. Lesson of the week, Feb 2003

MANAGEMENT M Sc module in Health Care management 2001

I have regularly attended management meetings in the Critical Care Directorate In Natal, South Africa I was involved in the organization of peripheral clinics run by the base Hospital As advanced trainee in ITU, I was responsible for the junior trainees on-call rota and teaching program

TEACHING M Sc module in Teaching and Learning for the Health Care Professional 2000 This has allowed me to regularly teach on other MSc courses Organizing the FRCA teaching course in the Royal Gwent Hospital In Natal, South Africa I was extensively involved in the teaching of nursing staff working in peripheral clinics. I store all my lectures and talks electronically as part of my portfolio

COURSES ATTENDED

FEEL Intensive ECHO training fir Intensivists, Leeds Intensive Care Update Part 1, 2, 3, London Safer patient Initiative Part 3 and Part 4, London Safer patient Initiative Part 1 and Part 2, London APLS, UHW Cardiff ADDRESS trial training meeting, London Difficult airway management course, UHW Cardiff Law and medicine, UHW Cardiff

2009 2008 2008 2007 2003 2003 2002 2001

Percutaneous Trachestomy course, Ninewells Hospital, Dundee 2002 Advances in peri-operative care, Bristol ATLS, Treliske Hospital,Truro Retrieval of the critically ill, Adelaide South Australia Peripheral clinic setup, Nwqelezana Hospital, South Africa 2001 1999 1997 1993

LEISURE INTERESTS Active interest in flying. I have completed several hours towards my PPL. Open water certification in SCUBA diving Windsurfing and skiing Tennis and squash

REFERENCES 1.Dr Mark Smithies Director of Critical Care Services at UHW ,Cardiff Address: 34 Lake Rd East Roath Park Cardiff CF12 5NN 2. Dr Ralph Vaughan Consultant Anaesthetist at UHW, Cardiff Address: 17 Ashtree Close Telephone No.: 029 20843051 Telephone No.: 029 20748384 (work) 029 20763751 (home)

Radyr Cardiff Cf15 8RX 3. Dr Mark Stacey Consultant Anaesthetist at UHW/Llandough Hospital,Cardiff Address: 24 Heol Don Whitchurch Cardiff CF14 2AS Telephone No.: 029 20638858