cruciferous vegetables & their benefit

21
Cruciferous Cruciferous How it helps cancer How it helps cancer http:// http:// www.whfoods.com www.whfoods.com

Upload: drericberg

Post on 24-Jan-2015

230 views

Category:

Health & Medicine


0 download

DESCRIPTION

http://www.DrBerg.com Learn how cruciferous benefits

TRANSCRIPT

Page 1: Cruciferous Vegetables & their Benefit

CruciferousCruciferousHow it helps cancerHow it helps cancer

http://http://www.whfoods.comwww.whfoods.com

Page 2: Cruciferous Vegetables & their Benefit

How people get cancerHow people get cancer

►►If potentially toxic molecules are not If potentially toxic molecules are not properly and rapidly detoxified in the liver, properly and rapidly detoxified in the liver, they can damage cell membranes and they can damage cell membranes and molecules such as DNA within the cell molecules such as DNA within the cell nucleus. Such damage can start a chain nucleus. Such damage can start a chain reaction that may eventually lead to reaction that may eventually lead to carcinogenesiscarcinogenesis----cell deregulation and cell deregulation and uncontrolled growth. uncontrolled growth.

Page 3: Cruciferous Vegetables & their Benefit

2 methods of ridding cancer2 methods of ridding cancer

►►Cauliflower and other cruciferous Cauliflower and other cruciferous vegetables, such as vegetables, such as broccolibroccoli, , cabbagecabbage, and , and kalekale, have compounds which may help , have compounds which may help prevent cancer. These compounds appear prevent cancer. These compounds appear to (1) to (1) stop enzymes from activating cancerstop enzymes from activating cancer--causing agents in the bodycausing agents in the body, and (2) , and (2) increase increase the activity of enzymes that disable and the activity of enzymes that disable and eliminate carcinogenseliminate carcinogens. .

Page 4: Cruciferous Vegetables & their Benefit

Plant ChemicalsPlant Chemicals

►►We now know that cruciferous vegetables We now know that cruciferous vegetables contain both contain both glucosinolatesglucosinolates and and thiocyanatesthiocyanates (including (including sulforaphanesulforaphane and and isothiocyanateisothiocyanate). These compounds increase ). These compounds increase the liver's ability to the liver's ability to neutralize potentially neutralize potentially toxic substances.toxic substances.

Page 5: Cruciferous Vegetables & their Benefit

CancerCancer

►► New Research Explains How Cruciferous Vegetables New Research Explains How Cruciferous Vegetables Prevent CancerPrevent Cancer

►► Cabbage, cauliflower, broccoli, kale and Brussels sprouts Cabbage, cauliflower, broccoli, kale and Brussels sprouts help prevent cancer. When these vegetables are help prevent cancer. When these vegetables are cut, cut, chewed or digestedchewed or digested, a sulfur, a sulfur--containing compound is containing compound is brought into contact with the enzyme, resulting in the brought into contact with the enzyme, resulting in the release of a highly reactive compound called release of a highly reactive compound called isothiocyanatesisothiocyanates. . IsothiocyanatesIsothiocyanates are not only potent are not only potent triggers of the liver’s Phase II enzymes, which detoxify triggers of the liver’s Phase II enzymes, which detoxify carcinogens, but research recently conducted at the carcinogens, but research recently conducted at the Institute for Food Research in the U.K. shows one of these Institute for Food Research in the U.K. shows one of these compounds, compounds, allylallyl isothicyanateisothicyanate, also inhibits cell division , also inhibits cell division and stimulates programmed cell death in human tumor and stimulates programmed cell death in human tumor cells. cells.

Page 6: Cruciferous Vegetables & their Benefit

How it works in colon cancerHow it works in colon cancer

►► Cell replication (when the parent cell divides to form two Cell replication (when the parent cell divides to form two daughter cells) occurs in a fourdaughter cells) occurs in a four--stage process. After the stage process. After the cell divides (the first stage), pole structures are created cell divides (the first stage), pole structures are created called spindles (the second or metaphase). If anything called spindles (the second or metaphase). If anything interferes with the construction and deconstruction of interferes with the construction and deconstruction of these spindles, the cell division process stops, and the these spindles, the cell division process stops, and the damaged cells commit suicidedamaged cells commit suicide. Researchers, have shown . Researchers, have shown that that isothiocyanateisothiocyanate disrupts the metaphase, thus disrupts the metaphase, thus preventing the cell division of the colon cancer cells. Their preventing the cell division of the colon cancer cells. Their research are published in the July 2004 issue of research are published in the July 2004 issue of CarcinogenesisCarcinogenesis. (June 3, 2004) . (June 3, 2004)

Page 7: Cruciferous Vegetables & their Benefit

How it works in breast cancerHow it works in breast cancer

►► SulforaphaneSulforaphane, a compound formed when , a compound formed when cruciferous vegetables are cruciferous vegetables are chopped or chewedchopped or chewed, , is already known to trigger the liver to produce is already known to trigger the liver to produce enzymes that enzymes that detoxify cancerdetoxify cancer--causing chemicalscausing chemicals, , inhibit chemicallyinhibit chemically--induced breast cancersinduced breast cancers in animal in animal studies, and studies, and induce colon cancer cells to commit induce colon cancer cells to commit suicide.suicide. Now, a study published in the September Now, a study published in the September 2004 issue of the 2004 issue of the Journal of NutritionJournal of Nutrition shows shows sulforaphanesulforaphane also helps also helps stop the proliferation of stop the proliferation of breast cancer cells, even in the later stages of breast cancer cells, even in the later stages of their growththeir growth. (October 19, 2004) . (October 19, 2004)

Page 8: Cruciferous Vegetables & their Benefit

Prostate cancerProstate cancer

►► Scientists tested turmeric (spice), a concentrated source of Scientists tested turmeric (spice), a concentrated source of the the phytonutrientphytonutrient curcumincurcumin, along with , along with phytochemicalsphytochemicalsabundant in cruciferous vegetables including cauliflower, abundant in cruciferous vegetables including cauliflower, cabbage, broccoli, Brussels sprouts, kale, kohlrabi and cabbage, broccoli, Brussels sprouts, kale, kohlrabi and turnips. turnips.

►► When tested singly, both cruciferous and When tested singly, both cruciferous and curcumincurcumin greatly greatly retarded the growth of human prostate cancerretarded the growth of human prostate cancer cells cells implanted in immuneimplanted in immune--deficient mice. In mice with welldeficient mice. In mice with well--established prostate cancer tumors, neither cruciferous and established prostate cancer tumors, neither cruciferous and curcumincurcumin by itself had a protective effect, by itself had a protective effect, but when but when combined, they significantly reduced both tumor combined, they significantly reduced both tumor growth and the ability of the prostate cancer cells growth and the ability of the prostate cancer cells to spread (metastasize) in the test animals.to spread (metastasize) in the test animals.

Page 9: Cruciferous Vegetables & their Benefit

Combinations of foodsCombinations of foods

►► The researchers believe the combination of The researchers believe the combination of cruciferous vegetables and cruciferous vegetables and curcumincurcumin could be an could be an effective therapy not only to prevent prostate effective therapy not only to prevent prostate cancer, but to inhibit the spread of established cancer, but to inhibit the spread of established prostate cancers. prostate cancers.

►► Use sautéed Use sautéed cauliflower spiced with turmericcauliflower spiced with turmeric..►► For protection against prostate cancer, cut For protection against prostate cancer, cut

cauliflower florets in quarters and let sit for 5cauliflower florets in quarters and let sit for 5--10 10 minutes; this allows time for the production of minutes; this allows time for the production of phenethylphenethyl isothiocyanatesisothiocyanates, which form when , which form when cruciferous vegetables are cut, but stops when cruciferous vegetables are cut, but stops when they are overthey are over--heated. heated.

Page 10: Cruciferous Vegetables & their Benefit

KaleKale

►► Kale stands out as an antiKale stands out as an anti--cancer food. It’s the cancer food. It’s the organosulfurorganosulfur compounds in this food that have compounds in this food that have been main subject of been main subject of phytonutrientphytonutrient research, and research, and these include the these include the glucosinolatesglucosinolates and the and the methyl methyl cysteinecysteine sulfoxidessulfoxides. Although there are . Although there are over 100 different over 100 different glucosinolatesglucosinolates in plants, only in plants, only 1010--15 are present in kale and other 15 are present in kale and other BrassicasBrassicas. . Yet Yet these 10these 10--15 15 glucosinolatesglucosinolates appear able to lessen appear able to lessen the occurrence of a wide variety of cancers, the occurrence of a wide variety of cancers, including breast and ovarian cancersincluding breast and ovarian cancers..

Page 11: Cruciferous Vegetables & their Benefit

CataractsCataracts

►► In addition to its unique In addition to its unique organosulfurorganosulfur compounds, compounds, kale kale is wellis well--known for its known for its carotenoidscarotenoids, especially , especially luteinlutein and and zeaxanthinzeaxanthin. These . These carotenoidscarotenoids act like act like sunglass filters and prevent damage to the eyes sunglass filters and prevent damage to the eyes from excessive exposure to ultraviolet lightfrom excessive exposure to ultraviolet light. . Studies have shown the protective effect of these Studies have shown the protective effect of these nutrients against the risk of cataracts, where nutrients against the risk of cataracts, where increased eye cloudiness leads to blurred vision. In increased eye cloudiness leads to blurred vision. In one study, people who had a diet history of eating one study, people who had a diet history of eating luteinlutein--rich foods like kale had a 50% lower risk for rich foods like kale had a 50% lower risk for new cataracts. new cataracts.

Page 12: Cruciferous Vegetables & their Benefit

BroccoliBroccoli

►► Like other cruciferous vegetables, broccoli contains Like other cruciferous vegetables, broccoli contains phytochemicalsphytochemicals----sulforaphanesulforaphane and the and the indolesindoles----with with significant antisignificant anti--cancer effects. Research on cancer effects. Research on indoleindole--33--carbinolcarbinol shows this compound shows this compound helps deactivate a helps deactivate a potent estrogen potent estrogen (4(4--hydroxyestrone) that promotes tumor hydroxyestrone) that promotes tumor growth, especially in estrogengrowth, especially in estrogen--sensitive breast cells, sensitive breast cells, while while at the same time increasing the level of 2at the same time increasing the level of 2--hydroxyestrone, a form of estrogen that can be hydroxyestrone, a form of estrogen that can be cancercancer--protective.protective. IndoleIndole--33--carbinol has been shown to carbinol has been shown to suppress not only breast tumor cell growth, but also cancer suppress not only breast tumor cell growth, but also cancer cell metastasiscell metastasis (the movement of cancerous cells to other (the movement of cancerous cells to other parts of the body). parts of the body).

Page 13: Cruciferous Vegetables & their Benefit

TumorsTumors

►►When researchers at Johns Hopkins studied When researchers at Johns Hopkins studied the effect of the effect of sulphoraphanesulphoraphane on tumor on tumor formation in lab animals, those animals formation in lab animals, those animals given given sulforaphanesulforaphane had fewer tumors, and had fewer tumors, and the tumors that did develop grew more the tumors that did develop grew more slowly and weighed less, meaning they slowly and weighed less, meaning they were smaller. were smaller. http://http://www.brassica.com/sci/patents.htmwww.brassica.com/sci/patents.htm

Page 14: Cruciferous Vegetables & their Benefit

Broccoli versus SproutsBroccoli versus Sprouts

►►A study published in the September 2004 A study published in the September 2004 issue of the issue of the Journal of NutritionJournal of Nutrition found found sulforaphanesulforaphane also helps stop the also helps stop the proliferation of breast cancer cells, even in proliferation of breast cancer cells, even in the later stages of their growth. (If broccoli the later stages of their growth. (If broccoli isn't one of your favorite vegetables, isn't one of your favorite vegetables, remember that a remember that a tablespoon of broccoli tablespoon of broccoli sprouts contains as much sprouts contains as much sulforaphanesulforaphaneas is found in a whole pound of adult as is found in a whole pound of adult broccolibroccoli.).)

Page 15: Cruciferous Vegetables & their Benefit

SproutsSprouts

►►Researchers estimate that broccoli sprouts Researchers estimate that broccoli sprouts contain 10contain 10--100 times the power of 100 times the power of mature broccolimature broccoli to boost enzymes that to boost enzymes that detoxify potential carcinogens! A healthy detoxify potential carcinogens! A healthy serving of broccoli sprouts in your salad or serving of broccoli sprouts in your salad or sandwich can offer as much or even more sandwich can offer as much or even more protection against cancer as larger amounts protection against cancer as larger amounts of mature broccoli. of mature broccoli.

Page 16: Cruciferous Vegetables & their Benefit

Stomach cancerStomach cancer

►► Regularly eating broccoli sprouts may help prevent Regularly eating broccoli sprouts may help prevent stomach cancer by reducing stomach cancer by reducing HelicobacteriHelicobacteri pyloripylori (H. pylori) (H. pylori) infection, which is known to cause gastritis (stomach infection, which is known to cause gastritis (stomach inflammation) and peptic ulcer, suggests a study published inflammation) and peptic ulcer, suggests a study published in an early 2005 issue of in an early 2005 issue of InflammopharmacologyInflammopharmacology. .

►► The research team, led by The research team, led by AkinoriAkinori YanakaYanaka of the University of the University of Tsukuba, Japan, found that in patients with of Tsukuba, Japan, found that in patients with H.pyloriH.pyloriinfection, infection, a diet including 100 grams of broccoli a diet including 100 grams of broccoli sprouts per day (about 3 ounces)sprouts per day (about 3 ounces) resulted in a resulted in a significant reduction of H. pylori and significant reduction of H. pylori and pepsinogenpepsinogen (a (a biomarker in the blood indicating the degree of gastritis). biomarker in the blood indicating the degree of gastritis).

Page 17: Cruciferous Vegetables & their Benefit

Broccoli sprouts vs. alfalfa sproutsBroccoli sprouts vs. alfalfa sprouts

►► The Japanese team recruited 40 patients infected with H. pylori.The Japanese team recruited 40 patients infected with H. pylori. Each day for Each day for two months, 20 patients ate a diet with 100 grams of two or thretwo months, 20 patients ate a diet with 100 grams of two or threee--day old day old sulforaphanesulforaphane--rich broccoli sprouts each day for two months, while the rich broccoli sprouts each day for two months, while the remaining 20 ate a diet with 100 grams of alfalfa sprouts instearemaining 20 ate a diet with 100 grams of alfalfa sprouts instead. d.

►► ""We wanted to test alfalfa spouts together with broccoli sproutsWe wanted to test alfalfa spouts together with broccoli sprouts," ," YanakaYanaka explained, "explained, "because the chemical constituents of the two plants because the chemical constituents of the two plants are almost identical, except that 100 grams of broccoli sprouts are almost identical, except that 100 grams of broccoli sprouts contain 250 milligrams of contain 250 milligrams of sulforaphanesulforaphane glucosinolateglucosinolate whereas alfalfa whereas alfalfa sprouts contain neither sprouts contain neither sulforaphanesulforaphane nor nor sulforaphanesulforaphaneglucosinolateglucosinolate."."

►► ((GlucosinolatesGlucosinolates, naturally occurring compounds in cruciferous vegetables such , naturally occurring compounds in cruciferous vegetables such as cauliflower and cabbage as well as broccoli, are as cauliflower and cabbage as well as broccoli, are enzymaticallyenzymatically converted converted into into sulforaphanesulforaphane and other bioactive components when the sprouts are and other bioactive components when the sprouts are chewed or cut.) chewed or cut.)

►► At the end of the twoAt the end of the two--month dietary regimen, patients month dietary regimen, patients consuming 100 consuming 100 grams of broccoli sprouts per day showed significantly less H. pgrams of broccoli sprouts per day showed significantly less H. pyloriyloriand markedly decreased and markedly decreased pepsinogenpepsinogen (an indicator of gastric atrophy). (an indicator of gastric atrophy). Those Those eating alfalfa sprouts did not show any effect.eating alfalfa sprouts did not show any effect.

Page 18: Cruciferous Vegetables & their Benefit

CabbageCabbage►► The study included hundreds of Polish women and PolishThe study included hundreds of Polish women and Polish--born women born women

in the U.S. who are part of the Polish Women's Health Study, a cin the U.S. who are part of the Polish Women's Health Study, a casease--control breast cancer study. Participants were given a food freqcontrol breast cancer study. Participants were given a food frequency uency questionnaire that assessed their cabbage consumption when they questionnaire that assessed their cabbage consumption when they were 12 to 13 years old and as adults. were 12 to 13 years old and as adults.

►► Compared with women who ate only one serving or less of cabbage Compared with women who ate only one serving or less of cabbage per week during adolescence, per week during adolescence, those who ate four or more those who ate four or more servings were 72% less likely to develop breast cancer as servings were 72% less likely to develop breast cancer as adults.adults.

►► In Poland, women typically eat In Poland, women typically eat an average of 30 pounds of an average of 30 pounds of cabbage and sauerkraut per year, while American women cabbage and sauerkraut per year, while American women consume just 10 pounds per year. Polish women also consume just 10 pounds per year. Polish women also traditionally eat more raw cabbage and sauerkraut in salads traditionally eat more raw cabbage and sauerkraut in salads or as a side dish.or as a side dish.

Page 19: Cruciferous Vegetables & their Benefit

Raw cabbageRaw cabbage

►► Cabbage foods were categorized as raw (raw Cabbage foods were categorized as raw (raw sauerkraut and fresh cabbage), shortsauerkraut and fresh cabbage), short--cooked cooked (steamed sauerkraut and cabbage), and long(steamed sauerkraut and cabbage), and long--cooked (hunter's stew, cabbage rolls, and cooked (hunter's stew, cabbage rolls, and pierogipierogi). ). Cabbage's protective effect was seen only Cabbage's protective effect was seen only for raw and shortfor raw and short--cooked cabbagecooked cabbage, , not longnot long--cookedcooked, which was eliminated from the analysis. , which was eliminated from the analysis. To promote the production of the most To promote the production of the most glucosinolatesglucosinolates, , slice or chop your cabbage and let slice or chop your cabbage and let sit for 5sit for 5--10 minutes before cooking, and cook 10 minutes before cooking, and cook lightly, steaming or sautéing for 5 minutes or lesslightly, steaming or sautéing for 5 minutes or less. .

Page 20: Cruciferous Vegetables & their Benefit

ParsleyParsley

►► Parsley’s volatile oils Parsley’s volatile oils –– particularly particularly myristicinmyristicin –– have been have been shown to inhibit tumor formation in animal studies, and shown to inhibit tumor formation in animal studies, and particularly, tumor formation in the lungs. particularly, tumor formation in the lungs. MyristicinMyristicin has has also been shown to activate the enzyme also been shown to activate the enzyme glutathioneglutathione--SS--transferasetransferase, which helps attach the molecule glutathione to , which helps attach the molecule glutathione to oxidized molecules that would otherwise do damage in the oxidized molecules that would otherwise do damage in the body. The activity of parsley’s volatile oils qualify it as a body. The activity of parsley’s volatile oils qualify it as a ““chemoprotectivechemoprotective”” food, and in particular, food, and in particular, a food that a food that can help neutralize particular types of carcinogenscan help neutralize particular types of carcinogens(like the (like the benzopyrenesbenzopyrenes that are part of that are part of cigarette smoke, cigarette smoke, charcoal grill smoke, and the smoke produced by charcoal grill smoke, and the smoke produced by trash incinerators). trash incinerators).

Page 21: Cruciferous Vegetables & their Benefit

BeetsBeets

►►The pigment that gives beets their rich, The pigment that gives beets their rich, purplepurple--crimson colorcrimson color----betacyaninbetacyanin----is also a is also a powerful cancerpowerful cancer--fighting agent. Beets' fighting agent. Beets' potential effectiveness against colon cancer, potential effectiveness against colon cancer, in particular, has been demonstrated in in particular, has been demonstrated in several studies. several studies.