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    HospitalCrash Cart - MICU

    Yatska CartagenaJuan Morales

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    Objectives

    After this presentation the studentswill be able to:

    Define the term crash cart.

    Understand the purpose of

    crash cart.

    Identify the content of crash

    cart, their use and the nursing

    consideration for all the:

    Medications

    Supplies

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    Definition crash cart

    A crash cart or code cart is a special mobile storage unit with drawers

    used in health care facilities and emergency rooms that contain the

    necessary medications and equipment to respond to a cardiopulmonary

    arrest.

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    Purpose of the Crash Cart

    The purpose of the crash cart is to have a portable life saving unit that

    contains all the medications, equipment and supplies necessary to initiate a

    treatment in emergency and life threatening situations on all health care

    facilities.

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    Classification

    Action

    Indication

    Contraindication

    Side effect

    Nursing Consideration

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    Medications included in the Crash Cart

    First Line drugs

    Oxygen

    Epinephrine

    Atropine Sulfate

    Antiarrhythmic Agents

    Lidocaine (Xylocaine)

    Procainamide (Ponestyl)

    Bretylium (Bretylol)

    Verapamil (Calan) Diltiazem (Cardizem)

    Adenosine (Adenocard)

    Aminoradone (Cordaron)

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    Medications included in the Crash Cart

    Miscellaneous

    Magnesium Sulfate

    Sodium Bicarbonate

    Calcium Chloride

    Calcium Gluconate Dextrose 50%

    Second Line Drugs

    Norepinephrine (Levophed)

    Dopamine (Intropin)

    Dobutamine (Dobutrex)

    Isoprotenerol (Isuprel)

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    Medications included in the Crash Cart

    Vasodilators/ Antihypertensive

    Nitroglycerine (Tridil)

    Anti-diuretic

    Vasopressin

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Epinephrine (1:10000)

    Classification

    Beta2 Adrenergic Agonists

    Action

    Stimulates beta receptors in lung.

    Relaxes bronchial smooth muscle.

    Increases vital capacity

    Increases BP, HR, PR

    Decreases airway resistance.

    Indication

    Asthma

    Bronchitis

    Emphysema

    All cardiac arrest, anaphylaxis

    Used for symptomatic bradycardia.

    Relief of bronchospasm occurring during anesthesia

    Exercised-induced bronchospasm

    Side Effects/Adverse Reactions

    nervousness, tremor, vertigo, pain, widened pulse

    pressure, hypertension, nausea

    headache

    Contraindications With angle-closure glaucoma, shock (other than

    anaphylactic shock), organic brain damage, cardiacdilation, arrhythmias, coronary insufficiency, orcerebral arteriosclerosis. Also contraindicated inpatient receiving general anesthesia with halogenatedhydrocarbons or cyclopropane and in patients in labor(may delay second stage)

    In conjunction with local anesthesia, epinephrine iscontraindicated for use in finger, toes, ears, nose, andgenitalia.

    In pregnant woman, drug is contraindicated.

    In breast feeding do not use the drug or stop breastfeeding.

    Nursing Management Monitor V/S. and check for cardiac dysrrhythmias

    Drug increases rigidity and tremor in patients withParkinsons disease

    Epinephrine therapy interferes with tests for urinarycatecholamine

    Avoid IM use of parenteral suspension into buttocks.Gas gangrene may occur

    Massage site after IM injection to counteract possiblevasoconstriction.

    Observe patient closely for adverse reactions. Notifydoctor if adverse reaction develop

    If blood pressure increases sharply, rapid-actingvasodilators such as nitrates or alpha blockers can begiven to counteract

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Atropine Sulfate (4mg/mL)

    Classification Anticholinergic

    Indication Pre-op meds/pre-anesthetic meds

    To restore cardiac rate and arterial pressure duringanesthesia when vagal

    To lessen the degree of A-V heart block

    To overcome severe carotid sinus reflex

    Antidote for cholinergic toxicity

    Side effects CNS: restlessness, ataxia, disorientation,

    hallucinations, delirium, coma, insomnia, agitation,confusion.

    CV: tachycardia, angina, arrhythmias, flushing.

    EENT: photophobia, blurred vision, mydriasis.

    GI: dry mouth, constipation, vomiting.

    GU: urine retention.

    Hematologic: leukocytosis

    Other: anaphylaxis

    Adverse effects CNS: headache, excitement.

    CV: palpitations

    GI: thirst, nausea

    Contraindications

    Hypersensitivity

    With acute angle closure glaucoma, obstructive

    uropathy, obstructive disease of GI tract, paralytic

    ileus, toxic megacolon, intestinal atony, unstable CV

    status in acute hemorrhage, asthma, or myasthenia

    gravis.

    Pregnant women.

    Nursing Management

    Monitor VS.

    Report increase HR

    Monitor for constipation, oliguria.

    Instruct to take 30 minutes before meals

    Eat foods high in fiber and drink plenty fluids.

    Can cause photophobia

    Instruct client not to drive a motor vehicle or

    participate in activities requiring alertness. Advise to use hard candy, ice chips, etc. for dry mouth.

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Lidocaine (Xylocaine) 100 mg bolus

    1 gm

    Classification CV drugs: Antiarrhythmics

    Anesthetic

    Action Increases electrical stimulation of ventricle and His-

    Purkinje system by direct action on tissues, resulting to

    decrease depolarization, automaticity and excitabilityin ventricles during diastolic phase

    Indication Anesthesia

    Arrhythmias

    Control of Status Epilepticus refractory to othertreatments

    Side Effects and Adverse Reactions GI disturbances, bradycardia, hypotension, convulsion,

    numbness of tongue, muscle twitching, restlessness,

    nervousness, dizziness, tinnitus, blurred vision, fetalintoxication, light headedness, drowsiness,apprehension, euphoria, vomiting, sensation of heat,respiratory arrest and CV collapse

    Contraindications Hypersensitivity

    Heart block

    Hypovolemia

    Adams stroke syndromes

    Infection at site of injection

    Nursing Management Assess pt before and after therapy

    Pts infusion must be on cardiac monitor

    Monitor ECG, if QT or QRS increases by 50% or more,withhold the drug

    Monitor BP, check for rebound HPN after 1-2 hrs

    Assess respiratory status, oxygenation and pulsedeficits

    Assess renal and liver function

    Monitor CNS symptoms

    Monitor blood levels

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Bretylium (Breytol) (500mg/10mL)

    Classification

    Antidysrhythmic

    Action

    Bretylol produces a prompt increase in ventricularfibrillation threshold, perhaps through postganglionicadrenergic blockade. It causes an initial release ofnorepinephrine from postganglionic nerve terminals.At present, its use is reserved for patients who fail torespond to lidocaine or other first-line

    antidysrhythmics. Indication

    Indicated in the prophylaxis and therapy of ventricularfibrillation.

    Indicated in the treatment of life-threateningventricular arrhythmias.

    Side effect/ Adverse effect

    Hypotension Hypotension and postural hypotension

    Nausea and vomiting

    Vertigo, dizziness, light-headedness and syncope

    Bradycardia, increased frequency of prematureventricular contractions, transitory hypertension,initial increase in arrhythmias, precipitation of anginalattacks, and sensation of substernal pressure.

    Renal dysfunction, diarrhea, abdominal pain, hiccups,erythematous macular rash, flushing, hyperthermia,confusion, paranoid psychosis, emotional liability,lethargy, generalized tenderness, anxiety, shortness ofbreath, diaphoresis, nasal stuffiness and mildconjunctivitis.

    Hyperthermia

    Contraindications

    There are no contraindications to use in treatment ofventricular fibrillation or life-threatening refractoryventricular arrhythmias.

    Nursing Management

    Assess and notify the doctor if the patient's medicalhistory include: any allergies, kidney disease, heartdisease, blocked blood vessels (aortic stenosis), lungproblems (pulmonary hypertension) because themedication is contraindicated with this conditions

    To avoid dizziness and lightheadedness, the patientshould remain lying down or, if necessary, get upslowly when rising from a seated or lying position.

    This medication should be avoid during pregnancyunless is clearly needed.

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Verapamil (Calan, Isoptin) (5mg/2mL)

    Classification

    Anti-anginal

    Anti-arrhythmics

    Anti-hypertensive

    Vascular headache suppressants

    Action

    Inhibits calcium transport into myocardial smoothmuscle cells

    Decreases SA and AV conduction and prolongs AVnode refractory period in conduction tissue

    Indication

    Hypertension

    Angina Pectoris

    Supraventricular Arrhythmia

    Atrial flutter/fibrillation

    Side Effects and Adverse Reactions

    CNS: abnormal dreams, anxiety, confusion,dizziness and headache

    EENT: blurred vision, epistaxis and tinnitus

    CV: arrhythmia, CHF, chest pain, bradycardia,hypotension and palpitations

    GU: dysuria, nocturia and polyuria

    GI: abnormal liver function, anorexia,constipation, diarrhea, nausea and vomiting

    Contraindications

    Hypersensitivity

    Sick sinus syndrome

    2nd or 3rd degree AV block

    CHF

    Cardiogenic shock

    Concurrent IV beta-blocker

    Nursing Management

    Monitor BP and pulse before therapy, duringtitration and therapy

    Monitor ECG, I&O, serum potassium and weight.

    Assess for CHF

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Diltiazem (Cardizem) (50mg/10mL)

    Classification

    Anti-anginals

    Antiarrhythmics

    Antihypertensive

    Ca channel blocker

    Action

    Inhibits calcium transport into myocardial smoothmuscle cells

    Systemic and coronary vasodilation

    Indication

    Hypertension

    Angina Pectoris

    Supraventricular Arrhythmia

    Atrial flutter/fibrillation

    Side Effects and Adverse and Reactions

    CNS: abnormal dreams, anxiety, confusion,dizziness and headache

    EENT: blurred vision, epistaxis and tinnitus

    CV: arrhythmia, CHF, chest pain, bradycardia,hypotension and palpitations

    GU: dysuria, nocturia and polyuria

    GI: abnormal liver function, anorexia,constipation, diarrhea, nausea and vomiting

    Contraindications

    Hypersensitivity

    Sick sinus syndrome

    2nd or 3rd degree AV block

    CHF

    Cardiogenic shock

    Concurrent IV beta-blocker

    Nursing Management

    Monitor BP and pulse before therapy, duringtitration and therapy

    Monitor I&O and weight

    Assess for CHF

    Routine serum Digoxin monitoring

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Adenosine (Adenocard) (6mg/2mL)

    Classification

    Nucleoside

    Indication

    To convert paroxysmalsupraventicular tachycardia (PSVT) tosinus rhythm

    Action

    A naturally occurring nucleoside that

    acts on the AV node to slowconduction and inhibit reentrypathways. Also useful in treatingPSVTs, including those with accessorybypass tracts (Wolff-Parkinson-Whitesyndrome)

    Adverse Reaction

    CNS: dizziness, light- headedness,numbness, tingling in arms,headache.

    CV: facial flushing.

    GI: nausea.

    Respiratory: dyspnea, shortness ofbreath, chest pressure.

    Contraindication Contraindicated in patients hypersensitivity

    to drugs.

    Contraindicated in those with second orthird-degree heart block or sinus nodedisease (such as sick sinus syndrome andsymptomatic bradycardia), except thosewith a peacemaker.

    Use cautiously in patients with asthma,emphysema, or bronchitis becausebronchoconstriction may occur.

    Nursing Management ALERT: by decreasing conduction through

    the AV node, drug may produce first-,second-or third-degree heart block.Patients who develop high-level heart blockafter a single dose shouldnt receiveadditional doses.

    ALERT: new arrhythmias, including heartblock and transient asystole, may develop;monitor cardiac rhythm and treat asindicated.

    If solution is cold, crystals may form; gentlywarm solution to room temperature. Dontuse solutions that arent clear.

    Drug lacks preservatives. Discard unusedportion.

    http://www.buyemp.com/tmp_image.php?item_id=11229435
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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Magnesium sulfate (50%(500mg/mL))

    Classification

    Anticonvulsant

    Indication

    Treatment of hypomagnesaemia accompanied bysigns of tetany

    Control of HTN

    Encephalopathy & convulsions

    Prevention & control of convulsions in patients w/preeclampsia or eclampsia

    Prevention of hypomagnesaemia in patients receivingTPN

    Action

    May decrease acetylcholine released by nerveimpulses, but its anticonvulsant mechanism isunknown

    Adverse Reactions

    flushing, sweating, hypotension, muscularweakness, sedation & confusion

    decreased deep tendon reflexes

    resp. paralysis

    Contraindications

    Heart block or myocardial damage

    Nursing Management

    Monitor the following: I.V.: Rapid administration:ECG monitoring, vital signs, deep tendon reflexes;magnesium, calcium, and potassium levels; renalfunction during administration.

    Obstetrics: Patient status including vital signs,oxygen saturation, deep tendon reflexes, level ofconsciousness, fetal heart rate, maternal uterineactivity.

    Oral: Renal function; magnesium levels; bowelmovements.

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Sodium Bicarbonate

    8.4% 50mEq/50mL

    Pediatric 4.2% 50 mEql

    Classification

    Alkalinizers

    Indication

    Metabolic acidosis

    Systemic or urinary alkalinization

    Antacid

    Cardiac arrest

    Action

    Restores buffering capacity of the body and

    neutralizes excess acid

    Adverse Reaction

    Tetany, edema, gastric distention, belching,

    flatulence, hypokalemia, metabolic alkalosis,

    hypernatremia, chemical cellulites because of

    alkalinity, pain, irritation, tissue necrosis,

    ulceration or sloughing at the site of

    infiltration

    Contraindications

    Contraindicated in patients with metabolic or

    respiratory alkalosis;

    Patients who are losing chlorides from vomiting or

    continuous GI suction;

    Patients taking diuretics known to produce

    hypochloremia alkalosis; and

    Patients with hypocalcemia in which alkalosis may

    produce tetany, hypertension, seizures, or heart

    failure.

    Oral sodium bicarbonate is contraindicated in patients

    with acute ingestion of strong mineral acids.

    Nursing Management

    Do not take drug with milk to avoid hypercalcemia,

    abnormally high alkalinity in tissues and fluids, orkidney stones.

    Do not give to patients with metabolic or respiratory

    alkalosis, and in those with hypocalcemia in which

    alkalosis may produce tetany, hypertension, seizures,

    or heart failure.

    Monitor for alkalosis by obtaining blood pH, PaO2,

    PCO2, and electrolyte levels

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Calcium Chloride (10% 100mg/mL)

    Classification

    Electrolytes

    Indication

    Hyperkalemia

    Hypocalcemia

    Hypermagnesia

    Action

    Increase the force of cardiac contractility, byinitiating myofibril

    shortening.

    In normally functioning hearts calcium will

    produce positive inotropic

    and vasoconstrictive effects and increase

    systemic arterial blood

    pressure.

    In abnormally functioning hearts calcium will

    produce positive

    inotropic effects may increase or decrease

    systemic vascular

    resistance.

    It also appears to increase ventricular

    automaticity.

    Adverse effect

    Metallic taste

    Burning

    Heat waves

    Bradycardia (may cause asystole)

    Hypotension

    Peripheral vasodilatation

    Cardiac arrhythmias

    Increased digitalis toxicity

    Extravasations with necrosis, sloughing and abscess

    formation

    Vasospasm in coronary and cerebral arteries.

    N/V

    Contraindications

    Hypercalcemia

    Digitalis toxicity

    VF during resuscitation

    Nursing Management Have patient remain recumbent for a short time after IV

    injection.

    Administer into ventricular cavity during cardiac

    resuscitation not in the myocardium

    Teach the patient to report loss of appetite, nausea,

    vomiting, abdominal pain, constipation, dry mouth, thirst,

    increased voiding.

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Dextrose 50% (500mL)

    Classification

    Intravenous & Other Sterile Solutions

    Indication

    Hypoglycemia

    Coma/seizure of unknown etiology

    Action:

    A simple water soluble sugar that minimizesglyconeogenesis and promotes anabolism in

    patients whose oral caloric intake is limited

    Adverse Reactions

    Local pain, vein irritation, thrombophlebitis &

    tissue necrosis in the event of extravasations.

    Fluid & electrolyte imbalance (eg hypokalemia,

    hypomagnesemia & hypophosphatemia); edema

    or water intoxication

    Contraindications

    Intracranial hemorrhage

    Increased intracranial pressure

    Nursing Measures:

    Monitor infusion rate frequently; ifsigns of fluid overload, turn off IV

    drip. Infusion may result in fluidoverload.

    Check IV site frequently and ifinfiltration is noted, turn off IV drip.

    Watch out for signs of fluid overload(distended neck veins (JVD), rapidrespirations, shallow tidal volume,

    fine auscultator crackles, dyspnea,and peripheral edema)

    Watch out for signs of infiltration(swelling and pain around IV site).

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Norepinephrine (Levophed) (1mg/mL)

    Classification

    Sympathomimetic

    Adrenergic

    Action

    Cause increase contractility and heart

    rate by acting on beta receptor in heart;

    also acts on alpha receptor causingvasoconstriction in blood vessel.

    Indication

    Cardiogenic shock

    Neurogenic shock

    Inotropic support

    Hemodinamically significant hypotension

    refractory to other sympathetic nerves

    Side Effects

    CNS: Headache, anxiety, dizziness, cerebral

    hemorrhage

    CV: tachycardia, hypertension

    GI: Nausea, vomiting

    GU: decrease urine output

    RESP: Dyspnea

    SYST: Anaphylaxis Contraindications

    Hypotensive patient with hypovolemia

    Nursing Management

    ECG during administration continuously

    Monitor BP and pulse q 2-3 minutes after

    parenteral route

    I/O ratio

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Dopamine (Intropin)

    400mgs/VIAL

    200 mg/10mL

    Classification

    Adrenergic drugs

    Action

    Stimulates dopaminergic and alpha and

    beta receptors of the sympathetic nervoussystem resulting in positive inotropic effect

    and increased CO

    Indication

    To treat shock and correct hemodynamic

    imbalances

    To correct hypotension

    To improve perfusion of vital organs

    To increase CO

    Side Effects

    CNS: headache an anxiety

    CV: tachycardia, angina, palpitations and

    vasoconstriction

    GI: nausea and vomiting

    Contraindications

    Hypersensitivity

    With uncorrected tachyarrhythmias

    Pheochromocytoma

    Ventricular Fibrillation

    Nursing Management

    Most patients received less than 20 mcg/kg/min

    Drugs isnt substitute for blood or fluid volumedeficit

    During infusion, monitor ECG, BP, CO, PR and

    color and temp of the limbs

    Do not confuse dopamine to dobutamine

    Check urine output often

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Dobutamine (Dobutrex)

    250 mgs/20 mL

    250mgs/VIAL

    Classification

    Adrenergic drugs

    Action

    Stimulates heart beta receptors to increase

    myocardial contractility and SV Indication

    To increase CO

    Treatment of cardiac decomposition

    Side Effects

    CNS: headache

    CV: HPN, tachycardia, palpitations and

    vasoconstriction

    GI: nausea and vomiting

    Contraindications

    Hypersensitivity

    Use cautiously in patients with history of HPN and

    AMI

    Nursing Management

    Before starting therapy, give a plasma volume

    expander to correct hypovolemia and a cardiac

    glycoside

    Monitor ECG, BP, pulmonary artery wedge

    pressure and CO

    Monitor electrolyte levels

    Dont confuse dobutamine to dopamine

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Isoprotenerol (Isuprel)0.2mg/mL

    Classification Sympathomimetic

    Action Stimulates beta1- and beta2-receptors resulting in

    relaxation of bronchial, GI, and uterine smoothmuscle, increased heart rate and contractility,vasodilation of peripheral vasculature

    Indication

    Hemodinamically significant bradycardia refractive toother therapy.

    Side Effects Cardiovascular: Angina, flushing, hyper-/hypotension,

    pallor, palpitation, paradoxical bradycardia (with tilttable testing), premature ventricular beats, Stokes-Adams attacks, tachyarrhythmia, ventriculararrhythmia

    Central nervous system: Dizziness, headache,nervousness, restlessness, Stokes-Adams seizure

    Endocrine & metabolic: Hypokalemia, serum glucose

    increased Gastrointestinal: Nausea, vomiting

    Neuromuscular & skeletal: Tremor, weakness

    Ocular: Blurred vision

    Respiratory: Dyspnea, pulmonary edema

    Miscellaneous: Diaphoresis

    Contraindications VF/VT

    Hypotension

    Ischemia Heart Disease

    Cardiac arrest

    Nursing Management Monitor ECG, heart rate, respiratory rate, arterial

    blood gas, arterial blood pressure, CVP; serum glucose,serum potassium, serum magnesium

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Amrinone (Inocar)

    Classification

    Calcium Channel Blockers

    Cardiotonic Agents

    Phosphodiesterase Inhibitor

    Vasodilator Agents

    Action

    Increases cardiac contractility, vasodilator. Acts by

    inhibiting the breakdown of both cAMP and cGMP by thephosphodiesterase (PDE3) enzyme

    Indications

    Only for treatment of the following documented life-

    threatening recurrent ventricular arrhythmias that do not

    respond to other antiarrhythmics or when alternative

    agents are not tolerated: Recurrent ventricular

    fibrillation, recurrent hemodynamically unstable

    ventricular tachycardia. Serious and even fatal toxicity

    has been reported with this drug; use alternative agents

    first; very closely monitor patient receiving this drug.

    Unlabeled uses: Treatment of refractory sustained or

    paroxysmal atrial fibrillation and paroxysmal

    supraventricular tachycardia; treatment of symptomatic

    atrial flutter.

    Side effects/ Adverse effect CNS: Malaise, fatigue, dizziness, tremors, ataxia,

    paresthesias, lack of coordination

    CV: Cardiac arrhythmias, CHF, cardiac arrest, hypotension

    EENT:Corneal microdeposits (photophobia, dry eyes, halos,blurred vision); ophthalmic abnormalities includingpermanent blindness

    Endocrine:Hypothyroidism or hyperthyroidism

    GI: Nausea, vomiting, anorexia, constipation, abnormal liverfunction tests,liver toxicity

    Respiratory: Pulmonary toxicitypneumonitis, infiltrates

    (shortness of breath, cough, rales, wheezes) Other: Photosensitivity, angioedema

    Contraindications

    Patients with history of hypersensitivity to the drug

    Nursing Management Monitor cardiac rhythm continuously.

    Monitor for an extended period when dosage adjustmentsare made.

    Monitor for safe and effective serum levels (0.52.5mcg/mL).

    Doses of digoxin, quinidine, procainamide, phenytoin, and

    warfarin may need to be reduced one-third to one-halfwhen amiodarone is started.

    Give drug with meals to decrease GI problems.

    Arrange for ophthalmologic exams; reevaluate at any sign ofoptic neuropathy.

    Arrange for periodic chest x-ray to evaluate pulmonarystatus (every 36 mo).

    Arrange for regular periodic blood tests for liver enzymes,thyroid hormone levels.

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Nytroglycerin (Tridil) 50mg/ VIAL

    250 mgs/ 10 mL

    Classification Antianginal

    Nitrate

    Vasodilator

    Coronary

    Action Relaxes the vascular smooth system

    Reduces myocardial oxygen consumption Reduces left ventricular workload

    Reduces arterial BP

    Reduces venous return

    Indication Angina pectoris

    CHF associated with AMI

    Cardiac load reducing agent

    Hypertensive Crisis

    Side effects CNS: headache, throbbing, dizziness, weakness.

    GI: nausea, vomiting

    Skin: Rash

    Adverse Reactions CV: orthostatic hypotension, flushing, fainting.

    EENT: sublingual burning.

    Skin: Cutaneous vasodilation, contact dermatitis(patch)

    Contraindications Contraindicated in patients hypersensitive to nitrates

    With early MI. (S.L. form), severe anemia, increase ICPangle-closure glaucoma, IV nitroglycerine is contraindicatedin patients with hypovolemia, hypotension, orthostatichypotension, cardiac tamponade restrictivecardiomyopathy, constrictive pericarditis.

    Nursing Interventions Record characteristics and precipitating factors of anginal

    pain.

    Monitor BP and apical pulse before administration and

    periodically after dose. Have client sit or lie down if taking drug for the first time.

    Client must have continuing EKG monitoring for IVadministration

    Cardioverter/ defibrillator must not be discharged throughpaddle electrode overlying

    Nitro-Bid ointment or the Transderm-Nitro Patch. Assistwith ambulating if dizzy.

    Instruct to take at first sign of anginal pain.

    May be repeated q 5 minutes to max. of 3 doses.

    If the client doesnt experience relief, advise to seek medicalassistance immediately.

    Keep in a dark colored container

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Calcium Gluconate

    Classification:

    Electrolytes

    Indication/Dosage:

    PO Hypocalcaemia 10-50 mmol/day. IV Hypocalcaemic

    tetany 2.25 mmol via slow injection, then 58-77mL of

    10% soln diluted and administered as a continuous IV

    infusion. Antidote in severe hypermagnesaemia;

    Severe hyperkalemia 10mL of 10% solution, repeat

    every 10 minutes if needed.

    Action:

    replaces Calcium and maintains Calcium level

    Adverse Reactions:

    GI irritation; soft-tissue calcification, skin sloughing or

    necrosis after IM/SC inj. Hypercalcaemia characterized

    by anorexia, nausea, vomiting, constipation,

    abdominal pain, muscle weakness, mentaldisturbances, polydipsia, polyuria, nephrocalcinosis,

    renal calculi; chalky taste, hot flushes and peripheral

    vasodilation. Potentially Fatal: Cardiac arrhythmias

    and coma.

    Nursing Measures:

    Make sure prescriber specifies form of calcium to be

    given; crash carts may contain both calcium gluconate

    and calcium chloride.

    Tell patient to take oral calcium 1 to 11/2 hours after

    meals if GI upset occurs.

    Give I.M. injection in gluteus region in adults and in

    lateral thigh in infants. Use I.M. route only in

    emergencies when no I.V. route is available because ofirritation of tissue by calcium salts.

    Tell patient to take oral calcium with a full glass of

    water.

    Monitor calcium levels frequently. Hypercalcemia may

    result after large doses in chronic renal failure. Report

    abnormalities.

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Amiodarone

    Classification:

    Cardiac Drugs

    Indication:

    Ventricular and supraventricular arrhythmias.

    Action:

    Blocks potassium chloride leading to

    prolongation of action potential duration.

    Adverse Reactions:

    Blue-grey discoloration of skin,

    photosensitivity, peripheral neuropathy,

    paraesthesia, myopathy, ataxia, tremor,

    nausea, vomiting, metallic taste,

    hypothyroidism, hyperthyroidism, alopecia,

    sleep disturbances, corneal microdeposits, hot

    flushes, sweating. Heart block, bradycardia,

    sinus arrest, hepatoxicity, heart failure.

    Potentially Fatal: Pulmonary toxicity includingpulmonary fibrosis and interstitial

    pneumonitis, hepatoxicity, thyrotoxicity.

    Ventricular arrhythmias, pulmonary alveolitis,

    exacerbation of arrhythmias and rare serious

    liver injury. Generally in patients with high

    doses and having preexisting abnormalities of

    diffusion capacity.

    Nursing Measures:

    Monitor cardiac rhythm continuously.

    Monitor for an extended period when dosage adjustments are

    made.

    Monitor for safe and effective serum levels (0.52.5 mcg/mL).

    Doses of digoxin, quinidine, procainamide, phenytoin, and

    warfarin may need to be reduced one-third to one-half when

    amiodarone is started.

    Give drug with meals to decrease GI problems.

    Arrange for ophthalmologic exams; reevaluate at any sign ofoptic neuropathy.

    Arrange for regular periodic blood tests for liver enzymes,

    thyroid hormone levels.

    Drug dosage will be changed in relation to response of

    arrhythmias; you will need to be hospitalized during initiation

    of drug therapy; you will be closely monitored when dosage is

    changed.

    Have regular medical follow-up, monitoring of cardiac rhythm,

    chest x-ray, eye exam, blood tests.

    These side effects may occur: Changes in vision (halos, dry

    eyes, sensitivity to light; wear sunglasses, monitor light

    exposure); nausea, vomiting, loss of appetite (take with meals;

    eat small, frequent meals); sensitivity to the sun (use a

    sunscreen or protective clothing when outdoors); constipation

    (a laxative may be ordered); tremors, twitching, dizziness, loss

    of coordination (do not drive, operate dangerous machinery,

    or undertake tasks that require coordination until drug effects

    stabilize and your body adjusts to it).

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    Medication Classification, Mechanism of action, uses,

    contraindication, side effects and nursing considerations

    Vasopressin

    Classification:

    Antidiuretic

    Action

    Increases cyclic adenosine monophosphate (cAMP)

    which increases water permeability at the renal tubule

    resulting in decreased urine volume and increased

    osmolality; causes peristalsis by directly stimulating

    the smooth muscle in the GI tract; direct

    vasoconstrictor without inotropic or chronotropic

    effects

    Adverse Reactions

    Cardiovascular: Arrhythmia, asystole (>0.04

    units/minute), blood pressure increased, cardiac

    output decreased (>0.04 units/minute), chest pain, MI,

    vasoconstriction (with higher doses), venous

    thrombosis

    Central nervous system: Pounding in head, fever,

    vertigo

    Dermatologic: Ischemic skin lesions, circumoral pallor,

    urticaria

    Gastrointestinal: Abdominal cramps, flatulence,

    mesenteric ischemia, nausea, vomiting

    Genitourinary: Uterine contraction

    Neuromuscular & skeletal: Tremor

    Respiratory: Bronchial constriction

    Indications Adjunct in the treatment of GI hemorrhage and

    esophageal varices; pulseless arrest (ventriculartachycardia [VT]/ventricular fibrillation [VF],asystole/pulseless electrical activity [PEA]);vasodilatory shock ; donor management in brain-deadpatients .

    Contraindications Hypersensitivity to vasopressin or any component of

    the formulation

    Nursing consideration

    Evaluate patient history closely for use cautions.

    Assess potential for interactions with otherpharmacological agents patient may be taking (eg,concurrent use that will block or enhance antidiureticresponse).

    Note: Dosing and administration vary according topurpose for use. I.V. requires use of infusion pump andclose monitoring to prevent extravasation (may causesevere necrosis and gangrene).

    Assess results of laboratory tests, therapeutic

    effectiveness, and adverse response (eg, cardiacstatus, blood pressure, CNS status, fluid balance, signsor symptoms of water intoxication, intranasalirritation) on a regular basis during therapy.

    Teach patient possible side effects/appropriateinterventions and adverse symptoms to report.

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    Crash Cart

    *** Its important to ensure that unless

    is being used, this cart need to have a

    security seal.

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    Equipment on top of

    the crash cart

    Portable monitor/defibrillator

    AMBU-SPUR

    Laryngoscope set

    Adult Pro-pads radiolucent electrodes

    Pacer cable

    Drip stand

    2 - #11 blade

    Laryngoscope

    Adult laryngoscope with blade

    Pediatric laryngoscope with blade

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    Equipment basket on

    top of the crash cart 5- tongue depressor

    2 Sterile gauze

    2 Berman Airways

    2- Sterilization Pouch

    2 Septra 360 Electro Gel

    1- Intubation Stylet

    5 Endotracheal tubes holder with releasable

    cable tie. 1 Nasal Cannula tube

    1 Medical Recording Chart

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    Equipment on side

    of the crash cart

    Oxygen: Pressure reducing valve

    Pressure gauge

    Nipple adaptor

    Oxygen tubing connected to the flow

    meter

    5 package - EKG Conductive Adhesive

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    Equipment on side

    of the crash cart

    Endotracheal tubes

    Adult: 6.5, 7, 7.5, 8

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    1st Drawer on top of the crash cart

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    Equipment on Crash Cart

    1st Drawer Medications

    Epinephrine 1:10,000, (0.1 mg/mL) 5 IV JECT

    Dextrose 50 % 2 IV JECT

    Vasopressin 20 units/AMP 4 VIALS

    Atropine Sulfate 0.4 mg/ Ml

    1 IV JECT Calcium Gluconate 10 %

    5 VIALS

    Dopamine 200 mg/10 Ml - 5 VIALS

    Adenosine 6mg/2mL 2 IV JECT

    Dobutamine 250 mgs/20 mL - 3 VIALS

    Verapamil 5mg/ 2mL 2 AMP

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    2nd Drawer

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    Equipment on Crash Cart

    2nd Drawer - IV & Blood Draw Supply

    15 - Angiocath Needles Sizes:

    18G

    20G

    22G

    1 and 1.5 in

    6 - Butterflies Sizes:

    18G

    20G

    22G

    10 Vacutainers

    6 - non sterile glove

    4 Sterile Gauze 10 x 10

    20 Syringes: 3mL

    5mL

    10mL

    20mL

    Lab specimen tube

    Alcohol

    4 Tourniquet

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    Needles and Syringes

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    3rd Drawer

    Medications

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    Equipment on Crash Cart

    3rd Drawer - Medications Dextrose 50 %

    4 IV JECT

    Vasopressin 20 units/AMP 2 AMPS

    Sodium Bicarbonate 8.4 % 50 mEq 10 IV JECT

    Sodium Bicarbonate Pediatric 4.2 % 50 mEq 5 IV JECT

    Lidocaine (Xylocaine) 100 mg Bolus - 5 IV JECT

    1 GM 3 VIAL

    Epinephrine 1:10,000, (0.1 mg/mL) 15 IV JECT

    Adenosine 6mg/2mL 5 VIALS

    Calcium Chloride10% 3 IV JECT

    Calcium Gluconate 10 % 5 VIALS

    Diltiazem, refrigerated 50 mg - 4 VIALS

    50 mg/ 10mL 6 VIALS

    Amioradone HCL 150 mg/ 3mL 3 AMP

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    Equipment on Crash Cart

    3rd Drawer Medications

    Atropine Sulfate 0.4 mg/mL 10 AMP

    10 VIALS

    Verapamil 5mg/ 2mL 5 VIALS

    3 AMP

    Magnesium Sulfate 50% 4 IV JECT

    Norepinephrine Bitartrate 1mg/ml 3 AMP

    Dobutamine 250 mgs/ VIAL 5 VIALS

    Dopamine 200 mg/10 Ml - 4 VIALS

    400mgs/VIAL 5 VIALS

    Nitroglycerine 250mgs/ 10 Ml 2 VIALS

    50 mg/ VIAL 2 VIALS

    Bretylium 500 mg/ 10mL 5 AMP

    Isoproterenol 0.2 mgmL 5 AMP

    Pronestyl 1GM 2 VIALS

    h

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    4th Drawer

    IV Solutions and Tubing

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    Equipment on Crash Cart

    4th Drawer IV solutions and Tubing

    2 - IV care set

    2 - Micro-drip IV tubing

    2 - Macro-drip IV tubing

    2 - Secondary line IV

    tubing 2 Nitroglycerine IV set

    4 0.45 SS/50mL

    2 D/W 250mL

    2 D/W 500mL

    1 - N/S 9% 500mL

    1 - 0.45 SS/500mL D/W 250mL Glass Bottle

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    5th Drawer

    h

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    Equipment on Crash Cart

    5th Drawer Miscellaneous 2- 0.9% Sodium Chloride Irrigation 2- Irrigation Tray

    1- Adult Ambu bag with O2 connection

    1- Pediatric Ambu bag with O2 connection

    1 Nasal cannula

    1- Sterile Water

    3 Suction tubing

    1 Suction tubing tip 2 Sterile Gloves

    2 - Surgical gown

    2 Restraints

    2 Double lumen Catheters

    Endotracheal tubes: Adult: 6.5, 7, 7.5, 8

    Pediatrics:

    2.0 ET tubes without cuff

    3.0 ET tubes without cuff

    3.5 ET tubes without cuff

    4.0 ET tubes without cuff

    h i

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    Other equipment

    Oxygen and EKG machine

    On the side At the top