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Courses Specifications

Pharmacology and Biochemistry Courses

2016-2017

Faculty of Pharmacy


Delta University

for Science and Technology

Faculty of Pharmacy, Delta University for Science and Technology

1

Dept. of Pharmacology and Biochemistry

General Biology ........................................................................................................ 2

Medical and Pharmacy Terminology ..................................................................... 5

Biochemistry-1 .......................................................................................................... 9

Anatomy and Histology ......................................................................................... 13

Physiology ............................................................................................................... 18

Biochemistry-2 ........................................................................................................ 22

Pharmacology-1 ...................................................................................................... 26

Pharmacology-2 ...................................................................................................... 30

OTC Abuse ............................................................................................................. 35

Toxicology ............................................................................................................... 38

Clinical Biochemistry ............................................................................................. 42

Biostatistics ............................................................................................................. 46

Faculty of Pharmacy


Delta University



2

General Biology

1. Basic Information:

Course title: General Biology

Course code: PB 101

Department: Pharmacology and Biochemistry

Program on which the course is given: B. Pharm.

Faculty: Pharmacy

University: Delta University for Science and Technology

Academic level: Level one Fall Semester 2016-2017

Specialization: Faculty Basic Requirements

Prerequisite: None

Credit hours: Lecture: 2 Practical: 0 Total: 2

Approval date: 1/9/2016

2. Course Aims: The course aims to identify the different classes of organisms. Recognition of differences between

euokaryotes and prokaryotes cell structure is also considered. Otherwise, the course correlates biological

cell structure with its function in human body. Also, the course utilizes the proper biological terminology.

All these, could be achieved by working effectively through a team which develop self-learning and

enhance thinking.

3. Intended Learning Outcomes (ILOs):

a. Knowledge and understanding:

At the end of this course, student should be able to:

A1 a1. Identify the principles of basic science related to organisms classification

A2 a2. Recognize the chemical properties of various substances included in cell membrane structure

A4 a3. Enumerate the theories of identification of different chemicals communicated to the cells

b. Intellectual Skills:


B18 b1. Correlate biological structure with the function of the human cell

c. Professional and Practical Skills:


C1 c1. Utilize the medical terminology to communicate with biologists

C5 c2. Apply understanding of human biology of cells to good pharmacy practice

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3

d. General and Transferable Skills:


D3 d1. Effectively work in a team.

D6 d2. Develop the skills for self-learning

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1. Classification of organisms: Prokaryotes 2

2. Classification of organisms: Eukaryotes 2

3. Animal cell structure 2

4. Organelles functions 2

5. Biological membranes structure 2

6. Biological membranes Function 2

7. Mid-Term exam

8. Membrane active transport 2

9. Membrane passive transport 2

10. Communication between cells 2

11. Ligands & receptors 2

12. Tumors & apoptosis 2

13. Revision + Quiz 2

14. Final Exam

15. 24

5. Teaching and Learning Methods:

5.1. Lectures : white board and data show

5.2. Research in library and web

5.3. Presentation of search topics

6. Student Assessment Methods:

6.1.Assessment methods:

1. Written exam to assess knowledge, understanding, intellectual and professional skills

2. Course work to assess knowledge, understanding, intellectual skills, general skills and

confidence

3. Quizzes to assess knowledge, understanding and intellectual skills

6.2.Assessment schedule:

Assessment 1 Mid-term 7th week

Assessment 2 Quiz 13th week

Assessment 3 Written 14th &15th weeks

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4

6.3.Weighing of Assessments:

Mid-Term Exam & course work 25

Final-Term Exam 75

Oral Exam -

Practical Exam -

Total 100%

7. List of References:

No. Reference type

1. Lippincott Illustrated Reviews: Cell and Molecular Biology by Nalini

Chandar (Author), Susan Viselli (Author) 1st Edition (Lippincott

Illustrated Reviews Series, 2010)

textbook

2.

Cell Biology and Histology by Gartner, Leslie P., Hiatt, James

L., Strum, Judy, 5th Edition [Lippincott Williams & Wilkins,

2006]

textbook

3. www.pubmed.com website

4. www.freebooks4doctors.com website

8. Matrix of course contents versus ILOs:

No. Course contents Study

week

ILOs

knowledge

and

understanding

intellectual

skills

professional

and

practical

skills

general and

transferable

skills

1. Classification of organisms

Prokaryotes 1 a1

c1

2. Classification of organisms

Eukaryotes 2 a1 b1 c1

3. Animal cell structure 3 a2 b1 c2 d1

4. Organelles functions 4 a2 a3

b1 c2

5. Biological membranes structure 5 a2 b1 c2 d1

6. Biological membranes Function 6 a2 a3

b1 c2 d1

7. Membrane active transport 8 a3 c2 d2

8. Membrane passive transport 9 a3 c2 d2

9. Communication between cells 10 a3 c2 d2

10. Ligands & receptors 11 a3 c2 d2

11. Tumors & apoptosis 12 b1 c1 d2

Name Signature

Course Coordinator: Dr. Rania Khalil

Head of Department: Prof. Dr. Hassan El Kashif

Approval Date 1/9/2016

https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&text=Nalini+Chandar+PhD&search-alias=books&field-author=Nalini+Chandar+PhD&sort=relevancerank

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https://www.amazon.com/s/ref=dp_byline_sr_book_2?ie=UTF8&text=Susan+Viselli+PhD&search-alias=books&field-author=Susan+Viselli+PhD&sort=relevancerank

Faculty of Pharmacy


Delta University



5

Medical and Pharmacy Terminology 1. Basic Information:

Course title: Medical and Pharmacy Terminology

Course code: PB 102

Department: Pharmacology & Biochemistry


Faculty: Pharmacy


Academic level: 1st level Spring semester 2016/2017

Specialization: Faculty Basic Requirements

Prerequisite: None

Credit hours: Lecture:1 Practical: 0 Total:1


2. Course Aims:

2.1. Understand the concept and methods required in reading biological and health science

research.

2.2. Learning general and specialized terminology related to the general and specialized passages

taught in the reading and comprehension component.

2.3. Learn and understand: (1) medical terminology, (2) terms in pharmacy, and (3) principles of

health care language. Then how to develop the gained knowledge in communications with other

health-care providers.




A1 a1 Identify principles of basic terms in biology and health sciences that are relevant to

orienting students to pharmacy.

A22

a2 Recognize the proper pharmaceutical and medical terminology, abbreviations,

symbols, health reports and pharmacy practice.

a3 Manage forms and mechanics of writing which help students produce a readable

piece of writing with minimal, or no, language mistakes.



B21

b1 Predict the meaning of different medical terms.

b2 Define the structure of the word.

b3 Differentiate between different medical abbreviations.

Faculty of Pharmacy


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C1

c1 Analyze and monitor parts of a medical term.

c2 Utilize acquired information for interpretation of terms and abbreviations in pharmacy.

c3 Synthesize, analyze authentic materials and discuss issues presented in the scientific

literature.



D1

d1 Identify and interpret terminology presented in scientific investigations and studies.

d2 Communicate effectively with patients and health care professionals in a scientific

language.

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1. Introduction ,basic word parts, combining vowel rules ,word building

and interpreting medical terms 1

2. Basic word structure (prefixes ,roots, suffixes) 1

3. Prefixes 1

4. Prefixes 1

5. Suffixes 1

6. Suffixes 1

7. Mid-Term exam

8. Roots 1

9. Roots 1

10. Exercise 1

11. Medical abbreviations. 1

12. Medical abbreviations. 1

13. Exercise 1

14. Final Exam

15. 12


5.1. Lectures

5.2. Case discussions.

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2. Course work to assess knowledge, understanding, intellectual skills and general skills .


5. Case study to assess the skills of problem-solving and data presentation






Mid-Term Exam & course work 25%

final Exam 75%

Total 100%


No. Reference Type

1.

1.1. Medical Terminology for Health Care Professionals by Jane

Rice. (Pearson; 8th edition, 2014)

1.2. Medical Terminology With Human Anatomy by Jane Rice.

(Pearson; 5th edition, 2005)

1.3. Mosby’s medical dictionary by Mosby (Mosby; 9th edition,

2012)

Textbook

2. USA Journal of pharmacy Education, Electronic Journal Periodical

3. www.dictionary.com Website



week

ILOs

knowledge

and

understanding

intellectual

skills

professional

and

practical

skills

general and

transferable

skills

1.

Introduction, basic word

parts, combining vowel

rules, word building and

interpreting medical terms

1 a1 b2 c1

2. Basic word structure

(prefixes ,roots, suffixes) 2 a1 b1 c2

3. Prefixes 3 a1 b2 c1, c2

http://www.dictionary.com/

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4. Prefixes 4 a1 b2 c1, c2

5. Suffixes 5 a1 b2 c1, c2

6. Suffixes 6 a1 b2 c1, c2

7. Roots 8 a1 b2 c1, c2 d1

8. Roots 9 a1 b2 c1, c2 d1

9. Exercise 10 a2, a3 b1 c1, c2 d1,d2

10. Medical abbreviations. 11 a.1 b1,b3 c1, c2 d1,d2

11. Medical abbreviations. 12 a.1 b1,b3 c1, c2 d1,d2

12. Exercise 13 a2 b1,b3 c3 d1,d2

Name Signature

Course Coordinator: Dr. Eman Mahmoud

Head of Department: Prof. Hassan Elkashef


Faculty of Pharmacy


Delta University



9

Biochemistry-1 1. Basic Information:

Course title: Biochemistry-1

Course code: PB 221



Faculty: Pharmacy


Academic level: 2nd level Fall Semester 2016-2017

Specialization: Compulsory medical science course

Prerequisite: General Biology



2. Course Aims:

The course aims to understand the basic principles of biochemistry & their importance for living

organisms. Integration between chemistry structure and properties of carbohydrates and lipids, vitamins,

porphyrins and amino acids is also considered. Meanwhile, the course describe the general characters of

enzyme, mechanism, kinetics, and regulation of enzyme function and also, discuss cell respiration,

including electron transport chain and its coupling with oxidative phosphorylation as well as

understanding of chemiosmotic theory and energy production in the cell.




A1 a1. Identify the principles of medical science

A2 a2. Recognize the chemical structures of macronutrients

A11 a3.

Enumerate different types of enzymes and their theories of interactions including cell

respiration enzymes

a4. Define the principles of enzymes inhibition



B3 b1. Determine qualitative methods of analysis of simple proteins and carbohydrates

B16 b2.

Predict proteins (generally) and amino acids (specifically) in the sample provided, using

different color reaction

B18 b3.

Integrate basic biochemical facts of different conjugated proteins and carbohydrates in the

samples with clinical laboratory data

B21 b4. Interpret biochemical data

Faculty of Pharmacy


Delta University



10



C2 c1. Handle and dispose chemicals safely

C6 c2. Carry out laboratory diagnostic tests

C11 c3. Conduct experimental and research studies.



D3 d1. Work as a part of a team.

D4 d2. Evaluate information

D6 d3. Develop skills required for self-learning

4. Contents:

4.1.Lectures:

Week No. Topics No. of hours

1. Carbohydrates (monosaccharides) chemistry 2

2. Disaccharides chemistry 2

3. Polysaccharides chemistry 2

4. Simple lipids chemistry 2

5. Complex lipids chemistry 2

6. Lipoproteins 2

7. Mid-Term exam

8. Amino acids chemistry 2

9. Porphyrins 2

10. Enzymes 2

11. Vitamins 2

12. Biological oxidation and electron transport chain 2

13. Practical Exam 2

14. Final Exam

15. 24

4.2.Practical:

Week No. Topics No. of hours

1. Qualitative determination of monosaccarides 1

2. Qualitative determination of monosaccarides 1

3. Qualitative determination of disaccharides 1

4. Qualitative determination of disaccharides 1

5. Qualitative determination of polysaccharides 1

6. Qualitative determination of polysaccharides 1

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7. Mid-Term exam

8. Qualitative determination of alkaline proteins 1

9. Qualitative determination of alkaline proteins 1

10. Qualitative determination of neutral proteins 1

11. Qualitative determination of neutral proteins 1

12. Qualitative determination of albumin 1


14. Final Exam

15. 12


5.1. Lectures

5.2. Practical lab

5.3. Research in library and web, seminars




2. Practical exam to assess professional and practical skills


confidence

3. Oral exam to assess knowledge, understanding, intellectual skills, general skills and

confidence





Assessment 3 Practical 13th week

Assessment 4 Oral 14th &15thweeks

Assessment 5 Written 14th &15thweeks



Final-Term Exam 40

Oral Exam 10

Practical Exam 25

Total 100%

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12


No. Reference type

1.

1.1. Biochemistry (Lippincott Illustrated Reviews Series) by Denise R.

Ferrier (Lippincott Williams & Wilkins; 6th Edition, 2013)

1.2. Medical biochemistry by M.D. Chatterjea and Shinde Rana

(Jaypee Brothers Medical Pub.; 8th edition, 2011)

textbook

2. 2.1. www.pubmed.com

2.2. www.freebooks4doctors.com website



week

ILOs

knowledge

and

understanding

intellectual

skills

professional

and

practical

skills

general and

transferable

skills

1. Carbohydrates

(monosaccharides) chemistry 1 a1,a2 b1,b3 c1,c2,c3 d1

2. Disaccharides chemistry 2 a1,a2

b1,b3 c1,c2,c3 d1

3. Polysaccharides chemistry 3 a1,a2 b1,b3

c1,c2,c3 d1

4. Simple lipids chemistry 4 a1,a2 d1,d2

5. Complex lipids chemistry 5 a1,a2 d1,d2

6. Lipoproteins 6 a1,a2

d1,d3

7. Amino acids chemistry 8 a1,a2 b1,b2,b3,

b4 c1,c2,c3 d1

8. Porphyrins 9 a1,a2 d1

9. Enzymes 10 a3,a4 d1,d3

10. Vitamins 11 a2 d1

11. Biological oxidation and

electron transport chain 12 a3 d1

Course Coordinator: Dr. Samouel Tanas

Head of Department: Prof. Dr. Hassan El Kashef


https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&field-author=Denise+R.+Ferrier+PhD&search-alias=books&text=Denise+R.+Ferrier+PhD&sort=relevancerank


https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&text=M.+N.%2C+M.D.+Chatterjea&search-alias=books&field-author=M.+N.%2C+M.D.+Chatterjea&sort=relevancerank

https://www.amazon.com/s/ref=dp_byline_sr_book_2?ie=UTF8&text=Ph.D.+Shinde+Rana&search-alias=books&field-author=Ph.D.+Shinde+Rana&sort=relevancerank

http://www.pubmed/

Faculty of Pharmacy


Delta University



13

Anatomy and Histology 1. Basic Information:

Course title: Anatomy and Histology

Course code: PB 203



Faculty: Pharmacy




Prerequisite: General biology



2. Course Aims:

2.1 Know different histological tools and techniques for preparation of histological

sections.

2.2 Understand the bases of optics of light microscope, transmission and scanning by

electron microscopy.

2.3 Know theoretically and practically the normal structure of the cell by light and electron

microscope

2.4 Know the four basic tissues of the body (epithelium, connective tissue, muscle tissue

and nervous tissue) preparing students for studying human organs and systems.

2.5

Know the correlation between function and structure of various body systems from the

anatomical view such as digestive, respiratory, cardiovascular, urinary and nervous

systems

2.6 Understand the basic anatomical structure of different organs of human body




A1

a1. Define and describe the histological characteristics of normal cells, cytoplasmic

components, Membranous and non-membranous cell organelles.

a2. Describe the characteristics of the four basic tissues of human body.

a3. Describe and compare between different blood elements and their development

a4. Outline the clinical applications of the given anatomical facts

a5. Describe the basic structure of the different systems of the body and its correlation to

function

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B18

b1. Select appropriate methods to reveal specific microscopic features of cells and tissues

b2. Identify slides different from those seen during this course but of the same organs or

Tissues previously studied

b3. Interpret a complete blood picture report

b4. Compare the different anatomical structure of organs in the human body



C5

c1. Identify different cell organelles

c2. Assess the differences between different types of epithelium, connective tissue cells and

bone cells

c3. Identifiy different blood cells in blood films

c4. Apply the basic information to identify different types of tissues and organs and to

differentiate between surface markings



D1 d1. Enhance the communication skills through communication with colleagues during

preparing the essay.

D3 d2. Expres themselves freely and adequately by improving their descriptive capabilities

through writing an essay in groups.

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1. Cytology: Structure of cytoplasmic organelles and structure of the

nucleus

2

2. Epithelial tissue: Simple, stratified, neuron and glandular epithelium 2

3. Connective tissue Fibers, cells and types 2

4. Cartilage: Structure and different types of cartilage 2

5. Bone: cell types and ossification-Histology

Bone: cell types and ossification-Anatomy

2

6.

Muscular tissue: Skeletal muscles, smooth muscles and cardiac

muscles-Histology

Cardiovascular system and respiratory system-Anatomy

2

7. Mid-Term exam

8. Nervous tissue: Neuron, neuroglial cells and autonomic Ganglia 2

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9. Blood elements, Arteries and Veins. 2

10. Lymphatic system: Spleen, Thymus and Lymph nodes-Histology

Lymphatic system: Spleen, Thymus and Lymph nodes-Anatomy

2

11. Digestive system especially liver and pancreas-Histology

Digestive system especially liver and pancreas-Anatomy

2

12. Urinary and genital systems-Histology

Urinary and genital systems –Anatomy

2

13. Revision 2

14. Final Exam

15. 24

4.2.Practical:

Week

No. Topics

No. of

hours

1. Epithelial tissue : Simple, stratified ,neuronal and glandular epithelium 1

2. Epithelial tissue : Simple, stratified ,neuronal and glandular epithelium 1





7. Mid-Term exam

8. Bone: cell types and ossification. 1

9. Bone: cell types and ossification. 1

10. Muscular tissue: Skeletal muscles, smooth muscles and cardiac

muscles.

1

11. Muscular tissue: Skeletal muscles, smooth muscles and cardiac

muscles.

1

12. Revision 1


14. Final Exam

15. 12


5.1. Lectures

5.2. Practical Classes

5.3. Group discussion and homework

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16





3. Course work to assess knowledge, understanding, intellectual skills, general skills









Final-Term Exam 50%

Practical Exam 25%

Total 100%


No. Reference Type

1.

- Junqueira's basic histology: Text and Atlas, by Anthony

Mescher(McGraw-Hill Education/Medical; 13th edition, 2013)

- Ross and Wilson Anatomy and Physiology in Health and

Illness by Anne Waugh and Allison Grant (Churchill

Livingstone; 12th edition, 2014)

Textbook

2. Pubmed, Highwire, Biomednet, NIH. Website


No. Course

contents

Study

week

ILOs

knowledge and

understanding

intellectual

skills

professional

and practical

skills

general and

transferable

skills

1.

The Cell

structure &

organelles

1 a1 b1 c1 ----

2. The epithelium 2 a2 b , b2 c2 ----

3. The connective

tissue 3 a2 b1, b2 c2 d1, d2

4. Cartilage 4 a2 b1, b2 c2 d1, d2

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https://www.amazon.co.uk/s/ref=dp_byline_sr_book_2?ie=UTF8&text=Allison+Grant+BSc++PhD++RGN&search-alias=books-uk&field-author=Allison+Grant+BSc++PhD++RGN&sort=relevancerank

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5. bone 5 a2, a4, a5 b1, b2, b4 c2, c4 d1, d2

6. Muscle tissue 6 a , a4, a5 b1, b2, b4 c2, c4 d1, d2

7. Nervous Tissue 8 a2 b1, b2 c2 d1, d2

8. Blood and

vascular system 9 a2,a3 b3 c3 d1, d2

9. Lymphatic

system 10 a2, a4, a5 b1, b2, b4 c1, c4 d1, d2

10. Digestive

system 11 a2, a4, a5 b1, b2, b4 c1, c4 d1, d2

Name Signature

Course Coordinator: Prof. Dr. Sanaa Ahmad El-Sherbiny.

Head of Department: Prof. Dr. Hassan Elkashef.


Faculty of Pharmacy


Delta University



18

Physiology


Course title: Physiology

Course code: PB 204



Faculty: Pharmacy




Prerequisite: General biology



2. Course Aims:

1.1. Introduce the basic facts and principles of physiology.

1.2. To provide the students with the basic principles of human body hemostasis and the

consequences of the disturbances in the normal hemostasis.

1.3. To help the students to understand and interpret many pathophysiological disorders.

1.4. To integrate physiological data and mechanisms with the ongoing basic sciences anatomy,

histology and their clinical applications.




A1 a1. List the functional organization and structure of various body systems and its

relation to function.

A11

a2.

Describe the functional structure of the respiratory system, respiratory cycle, its

mechanism, regulation of normal respiration, respiratory functions of the blood

and some conditions related to disorders of the respiratory system.

a3. State the integration between different body systems to maintain homeostasis.

a4. Explain the feedback controls and auto-regulations that achieve the necessary

balances without which we could not be able to live.

a5. Describe the structure and functions of the Autonomic nervous system, its higher

centers, autonomic receptors and chemical transmitters

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B18

b1. Distinguish between physiological performance and pathophysiological disorders of

different body system.

b2. Examine the cardiac properties, cardiac cycle, factors affecting cardiac output and heart

rate.

b3. Analyze symptoms and manifestations of pathophysiological disorders in relation to the

normal physiology of human body.

b4. Assess the general classification of the central nervous system and describe the nerve

cells structures and their functions, the nerve impulse.

b5. Classify the endocrine system and describe the hormones secreted by each gland and

the different functions of them in the body.



C5

c1. Integrate physiology with other basic and clinical sciences.

c2. Employ the basic physiological measurements used to test different body functions.

c3. Apply clinical skill and tools in assessment of body function in health and in certain

specialty diseases.

c4. Predict and diagnose common endocrinal conditions: acromegaly dwarfism, thyroid

diseases, Cushing and Addison diseases.



D2 d1. Retrieve physiological information resources.

D3 d2. Work in a team and lead teams to participate effectively as member of the health care

team. Respect the role of staff and co-staff members.

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1-3 Physiology of autonomic nervous system 6

4-6 Physiology of endocrine system 6

7 Mid-Term exam

8-9 Physiology of cardiovascular system 4

10-13 Physiology of gastrointestinal, respiratory and urinary tracts 8

14. Final Exam

15.

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5.1. Lectures

5.2. Research activity and assignment





confidence







Mid-Term Exam & course work 25 %

Final-Term Exam 75 %

Total 100%


No. Reference type

1.

1.1. Ross and Wilson Anatomy and Physiology in Health and

Illness by Anne Waugh and Allison Grant (Churchill

Livingstone; 12th edition, 2014)

1.2.Hole's Essentials of Anatomy and Physiology. by David

Shier (Author), Jackie Butler (Author), Ricki Lewis

(Author). (McGraw-Hill Education; 12th edition, 2014)

1.3. Ganong's Review of Medical Physiology. by Kim E.

Barrett, Susan M. Barman, Scott Boitano and Heddwen L.

Brooks (McGraw-Hill Education; 25th edition, 2015).

textbook

2. http:// Advan.Physiology.org website

https://www.amazon.co.uk/s/ref=dp_byline_sr_book_1?ie=UTF8&text=Anne+Waugh+BSc%28Hons%29++MSc++CertEd++SRN++RNT++FHEA&search-alias=books-uk&field-author=Anne+Waugh+BSc%28Hons%29++MSc++CertEd++SRN++RNT++FHEA&sort=relevancerank

https://www.amazon.co.uk/s/ref=dp_byline_sr_book_2?ie=UTF8&text=Allison+Grant+BSc++PhD++RGN&search-alias=books-uk&field-author=Allison+Grant+BSc++PhD++RGN&sort=relevancerank

https://www.amazon.com/David-Shier/e/B001IO9RJ2/ref=dp_byline_cont_book_1

https://www.amazon.com/David-Shier/e/B001IO9RJ2/ref=dp_byline_cont_book_1

https://www.amazon.com/s/ref=dp_byline_sr_book_2?ie=UTF8&text=Jackie+Butler&search-alias=books&field-author=Jackie+Butler&sort=relevancerank

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https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&text=Kim+E.+Barrett&search-alias=books&field-author=Kim+E.+Barrett&sort=relevancerank

https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&text=Kim+E.+Barrett&search-alias=books&field-author=Kim+E.+Barrett&sort=relevancerank

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Faculty of Pharmacy


Delta University



21


No

. Course contents

Study

week

ILOs

knowledge

and

understandi

ng

intellectual

skills

professional

and practical

skills

general and

transferabl

e skills

1. Physiology of autonomic

nervous system 1-3 a1,a3,a4,a5 b1,b2,b4 c1,c2,c3 d1,d2

2. Physiology of endocrine

system 4-6 a1,a3,a4 b1,b3,b5 c1,c2,c3,c4 d1,d2

3. Physiology of cardiovascular

system 8-10 a1,a3,a4 b1,b2,b3 c1,c2,c3 d1,d2

4.

Physiology of gastrointestinal

tract, respiratory and urinary

tracts

11-13 a1,a2,a3,a4 b1,b3,b3 c1,c2, d1,d2

Name Signature

Course Coordinator: Prof. Dr. Hassan A. Elkashef

Head of Department: Prof. Dr. Hassan A. Elkashef


Faculty of Pharmacy


Delta University



22

Biochemistry-2 1. Basic Information:

Course title: Biochemistry-2

Course code: PB 222



Faculty: Pharmacy


Academic level: 2nd level Spring Semester 2016-2017


Prerequisite: Biochemistry-1



2. Course Aims:

The course aims to define the metabolic pathways for different macronutrients. Integration

between the metabolic facts and biochemical laboratory data is also considered. In addition, the

course carries out the biochemical laboratory quantitative analysis for diagnosis of different

organs dysfunctions which could conduct between experimental and research studies. Handling

of biological specimens is one of the most important aims of this course All these, could be

achieved by working effectively through a team which develop self-learning and enhance critical

thinking.




A1 a1. Identify the principles of medical science

A2 a2. Recognize the chemical properties of various substances as enzymes and regulators

A4 a3. Enumerate the theories of synthesis of natural products (carbohydrates, lipids, proteins)

A11 a4. Define the principles of body function in health and disease states

A15 a5. Define the basis of nutrition and metabolism



B3 b1. Determine suitable methods of analysis of macronutrients in biological fluids

B14 b2. Evaluate evidence-based biomedical metabolic information for each of macronutrient

B18 b3. Integrate basic biochemical facts with clinical laboratory data

B21 b4. Interpret biochemical data

Faculty of Pharmacy


Delta University



23



C2 c1. Handle and dispose biological specimen safely

C6 c2. Carry out laboratory diagnostic tests

C11 c3. Conduct experimental and research studies.

C14 c4. Employ different quantitative chemical and biological methods.



D3 d1. Work as a part of a team.

D4 d2. Evaluate information


4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1. Metabolism 2

2. Glycolysis 2

3. Gluconeogenesis 2

4. Krebs cycle 2

5. Pentose phosphate pathway 2

6. Glycogenesis & Glycogenolysis 2

7. Mid-Term exam ---

8. Fatty acids synthesis 2

9. Beta oxidation of fatty acids 2

10. Ketogenesis &ketolysis 2

11. Amino acids synthesis & degredation 2

12. Biologically active compounds synthetized from amino acids 2

13. Revision 2

14. Final Exam

15. 24

4.2.Practical/Tutorial:

Week

No. Topics

No. of

hours

1. Handling processes 1

2. Determination of blood glucose level 1

Faculty of Pharmacy


Delta University



24

3. Liver function, albumin & total protein determination 1

4. Bilirubin determination 1

5. AST & ALT determination 1

6. Kidney function creatinine determination 1

7. Mid-Term exam ---

8. Urea & uric acid determination 1

9. Lipid profile: Choresterol & triglyceride determination 1

10. Lipid profile: Choresterol & triglyceride determination 1

11. Calcium determination 1

12. Revision 1


14. Final Exam

15. 12


5.1. Lectures

5.2. Practical lab

5.3. Research in library and web.





3. Class work to assess knowledge, understanding, intellectual skills, general skills and

confidence


confidence







Assessment 4 Oral 14th &15thweeks


Faculty of Pharmacy


Delta University



25



Final-Term Exam 40

Oral Exam 10

Practical Exam 25

Total 100%


No. Reference type

1.

1.1. Biochemistry (Lippincott Illustrated Reviews Series) by Denise R.

Ferrier (Lippincott Williams & Wilkins; 6th Edition, 2013)

1.2. Medical biochemistry by M.D. Chatterjea and Shinde Rana

(Jaypee Brothers Medical Pub; 8th edition, 2011)

textbook


3. www.freebooks4doctors.com website



week

ILOs

knowledge

and

understanding

intellectual

skills

professional

and

practical

skills

general and

transferable

skills

1. Metabolism 1 a1,a2 b1

2. Glycolysis 2 a3,a4,a5 b1,b2,b3,b4 c1,c3,c4 d1

3. Gluconeogenesis 3 a3,a4,a5 b1,b2,b3,b4 c1,c3,c4 d1

4. Krebs cycle 4 a3 b1,b2 d1,d2

5. Pentose phosphate pathway 5 a3 b1 d1,d2

6. Glycogenesis &

Glycogenolysis 6

a3,a4,a5 b1,b2,b3 d1,d3

7. Fatty acids synthesis 8 a2,a3,a4,a5 b1,b2,b3,b4 c1,c3,c4 d1

8. Beta oxidation of fatty acids 9 a3,a4,a5 b1,b2,b3,b4 c1,c3,c4 d1

9. Ketogenesis &ketolysis 10 a3, a4,a5 b1,b2,b3 c2,c3,c4 d1,d3

10. Amino acids synthesis 11 a2,a3 b1,b3 c1,c2,c3,c4 d1

11. Amino acids degradation 12 a3,a5 b1,b3 c1,c2,c3,c4 d1

12. Biologically active compounds

synthetized from amino acids 13

a3,a5 b1,b4 c1,c2,c3,c4 d1

Name Signature

Course Coordinator: Dr. Rania Khalil





https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&text=M.+N.%2C+M.D.+Chatterjea&search-alias=books&field-author=M.+N.%2C+M.D.+Chatterjea&sort=relevancerank

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http://www.freebooks4doctors.com/

Faculty of Pharmacy


Delta University



26

Pharmacology-1 1. Basic Information:

Course title: Pharmacology-1

Course code: PB 331



Faculty: Pharmacy


Academic level: 3rd level Fall Semester 2016- 2017


Prerequisite: Physiology



2. Course Aims:

Provide knowledge and understanding of the basic principles of pharmacology

(pharmacokinetics and pharmacodynamics).

Introduce concepts of drug action at cell, tissue and system levels.

Illustrate different mechanisms of drug actions.

Provide comprehensive coverage of the major drug groups affecting different body

systems; autonomic nervous system, cardiovascular system, respiratory system, and

autacoids.




A8 a1. Outline the basic principles of pharmacology: pharmacokinetics, as well as

pharmacodynamics.

A13 a2.

Recognize different therapeutic classes of drugs, including their pharmacokinetics,

indications, adverse effects and interactions of medicines and their significance in

treatment of cardiovascular & autonomic diseases.

A14 a3. Identify the pharmacological effects of drugs acting on the respiratory system.



B9 b1. Predict the pharmacokinetics and pharmacodynamics of different classes of drugs

affecting autonomic nervous system.

B11 b2. Differentiate between different drugs used in treatment of cardiovascular diseases.

b3. Justify the adverse effects of different drugs and their relation to their indications

Faculty of Pharmacy


Delta University



27



C11 c1. Design an experimental protocol to show the effects of the drugs.

c2. Handle experimental animals as well as different isolated tissue preparations.

C13 c3. Utilize the problem-based learning to identify the interaction and adverse effects of

different agonists and antagonists of autonomic receptors.



D1 d1. Acquire proper skills for participation in various aspects of pharmacy professional

practice.

D2 d2. Retrieve drug information resources.

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1. Introduction 3

2. Pharmacokinetics and Pharmacodynamics 3

3. Introduction to autonomic nervous system 3

4. Sympathetic nervous system 3

5. Sympathetic and Parasympathetic nervous system 3

6. Parasympathetic nervous system 3

7. Mid-Term exam -

8. Autacoids 3

9. Bronchial asthma 3

10. Congestive heart failure 3

11. Anti-arrhythmic drugs 3

12. Anti-anginal drugs 3

13. Anti-hypertensive drugs 3

14. Final Exam

15. 36

Faculty of Pharmacy


Delta University



28

4.2.Practical/Tutorial:

Week

No. Topics

No. of

hours

1. Handling of animals 1

2. Route of administration 1

3. Dose calculation 1

4. Mice handling and injection 1

5. Hypnotics 1

6. Work activity 1

7. Mid-Term exam -

8. In-vitro experiments 1

9. Effect of known drugs on isolated rabbit intestine 1

10. Effect of unknown drugs on isolated rabbit intestine I 1

11. Effect of unknown drugs on isolated rabbit intestine II 1

12. Case study 1


14. Final Exam

15. 12


5.1. Lectures

5.2. Practical session using laboratory equipment and experimental animals

5.3. Assignments, PBL and case study.





3. Class work to assess knowledge, understanding, intellectual skills, general skills and

confidence


confidence







Assessment 4 Oral 14th &15th weeks


Faculty of Pharmacy


Delta University



29



Final-Term Exam 40%

Oral Exam 10%

Practical Exam 25%

Total 100%


No. Reference type

1.

1.1. Rang and Dale Pharmacology by James M. Ritter , Rod J. Flower

(Churchill Livingstone; 8th edition, 2015).

1.2. Lippincott Illustrated Reviews: Pharmacology by Karen Whalen

(Lippincott Williams & Wilkins; 6th edition, 2015).

textbook

2.

-British Journal of Pharmacology.

-Pharmacological Reviews.

-Journal of Pharmacology and Experimental Therapeutics.

-Trends in Pharmacological Sciences.

periodical

3. Pubmed, Highwire, Biomednet, NIH. website



week

ILOs

knowledge and

understanding

intellectual

skills

professional

and practical

skills

general and

transferable

skills

1. Introduction 1st a1

2. Pharmacokinetics and

Pharmacodynamics 2nd a1 b1 c2 d1

3. Introduction to autonomic

nervous system 3rd a1, a2 b1 c2, c3 d1

4. Sympathetic and

Parasympathetic nervous system 4th-6th a2 b1 c2, c3 d1

5. Autacoids 8th a3 b3 c2, c3 d1,d2

6. Bronchial asthma 9th a3 b2,b3 c1 d1, d2

7. Congestive heart failure 10th a2 b2,b3 c1 d1, d2

8. Anti-arrhythmic drugs 11th a2 b2,b3 c1 d1, d2

9. Anti-anginal drugs 12th a2 b2,b3 c1 d1, d2

10. Anti-hypertensive drugs 13th a2 b2,b3 c1 d1, d2

Name Signature

Course Coordinator: Prof. Dr. Hassan A. El-Kashef

Head of Department: Prof. Dr. Hassan A. El-Kashef


https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&field-author=James+M.+Ritter+DPhil+FRCP+FBPharmacolS+FMedSci&search-alias=books&text=James+M.+Ritter+DPhil+FRCP+FBPharmacolS+FMedSci&sort=relevancerank

https://www.amazon.com/s/ref=dp_byline_sr_book_2?ie=UTF8&field-author=Rod+J.+Flower+PhD+DSc+FBPharmacolS+FMedSci+FRS&search-alias=books&text=Rod+J.+Flower+PhD+DSc+FBPharmacolS+FMedSci+FRS&sort=relevancerank

https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&text=Karen+Whalen+PharmD++BCPS&search-alias=books&field-author=Karen+Whalen+PharmD++BCPS&sort=relevancerank

Faculty of Pharmacy


Delta University



30

Pharmacology-2


Course title: Pharmacology-2

Course code: PB 332



Faculty: Pharmacy


Academic level: 3rd level Spring Semester 2016- 2017


Prerequisite: Pharmacology-1



2. Course Aims:

1- Provide knowledge and understanding of the basic principles of centrally acting drugs

2- Provide comprehensive coverage of the major drug groups affecting the central nervous

system, gastrointestinal system, together with chemotherapeutic drugs (antimicrobial and

anticancer).

3-Provide comprehensive coverage of human body control and the activity of hormones and

diseases resulting from excess or deficiency of hormones.

4- Provide knowledge and understanding of the adverse effects and toxicity of centrally

acting drugs, hormones and chemotherapeutic drugs

5- Relate the misuse of centrally acting drugs and addiction.




A11 a1.

Recognize the etiology of major diseases affecting the central nervous system and

study different therapeutic classes of drugs, including the adverse reactions and

interactions of drugs and their significance in treatment.

A13 a2. Outline the mechanisms of action of different drugs and their indications.

A14 a3.

Discuss the proper therapeutic use of drugs in various diseases / disorders resulting

from deficiency or excess of hormones.

a4. Recognize the effects of chemotherapeutic drugs and their toxicity.

Faculty of Pharmacy


Delta University



31


[At the end of this course, student should be able to:

B9

b1. Rationalize the therapeutic use of drugs and predict the most clinically important

therapeutic agents in various disorders or diseases.

b2. Justify the use of antibiotics and chemotherapeutic agents to different diseases and

disorders.

B11 b3. Assess the drug interaction, adverse reactions and misuse of centrally acting drugs

and hormones.



C11 c1. Handle experimental animals as well as different isolated tissue preparations and

screen pharmacological effects of different drugs.

C13 c2. Assess risks concerning drug interaction and adverse reaction that require prompt

medical intervention and utilize the proper medications.

C21 c3. Manage side effects and toxicity of chemotherapeutic agents.



D1 d1. Communicate effectively with professionals and patients.

D3 d2. Work in a team, demonstrate critical thinking and decision making abilities.

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1-2

Sedatives & Hypnotics 2

Anesthesia 2

Antipsychotics 2

3-4

Antidepressants 2

Analgesics and anti-inflammatory 2

GIT drugs 2

5-6 Pituitary gland and adrenal cortex hormones 6

7 Mid-Term exam -

8-9 Pancreatic hormones 2

Thyroid hormones 4

10-13

Antimicrobial drugs 3

Anticancer drugs 6

Antiviral drugs and anthelmintics 3

14. Final Exam

-

15. 36

Faculty of Pharmacy


Delta University



32

4.2.Practical:

Week

No. Topics

No. of

hours

1. CNS depressants I 1

2. CNS depressants II 1

3. Analgesics I 1

4. Analgesics II 1

5. CNS stimulants I 1

6. CNS stimulants II 1

7. Mid-Term Exam -

8. Local anesthetics I 1

9. Local anesthetics II 1

10. Revision I 1

11. Revision II 1

12. Oral activity exam 1


14. Final Exam

15. 12


5.1. Lectures

5.2. Practical session using laboratory equipment and experimental animals

5.3. Assignments, PBL or case study.






confidence

3. Oral exam to assess knowledge, understanding, intellectual skills, general skills



Faculty of Pharmacy


Delta University



33









Final-Term Exam 40%

Oral Exam 10%

Practical Exam 25%

Total 100%


No. Reference type

1.

1.1. Rang and Dale Pharmacology by James M. Ritter , Rod J.

Flower (Churchill Livingstone; 8th edition, 2015).

1.2. Lippincott Illustrated Reviews: Pharmacology by Karen

Whalen (Lippincott Williams & Wilkins; 6th edition, 2015).

textbook

2.

-British Journal of Pharmacology.

-Pharmacological Reviews.

-JPET.

periodical

3. Internet sites (Pubmed, Highwire, Biomednet, NIH). website



week

ILOs

knowledge

and

understanding

intellectual

skills

professional

& practical

skills

general and

transferable

skills

1. Sedatives & Hypnotics

1st &2nd

a1,a2 b1 c1, c2 d1, d2

2. Anesthesia a2 b3 c1, c2 d1, d2

3. Antipsychotics a1,a2 b1 c1, c2 d1, d2

4. Antidepressants

3rd &4th

a1,a2 b1 c1, c2 d1, d2

5. Analgesics and anti-inflammatory a1,a2 b1 c1, c2 d1, d2

6. GIT drugs a2 b1 c2 d1, d2

7. Pituitary gland & adrenal cortex

hormones 5th&6th a2,a3 b1, b3 c2 d1, d2

https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&field-author=James+M.+Ritter+DPhil+FRCP+FBPharmacolS+FMedSci&search-alias=books&text=James+M.+Ritter+DPhil+FRCP+FBPharmacolS+FMedSci&sort=relevancerank





Faculty of Pharmacy


Delta University



34

8. Pancreatic hormones 8th&9th

a2,a3 b1, b3 c2 d1, d2

9. Thyroid hormones a2,a3 b1, b3 c2 d1, d2

10. Antimicrobial drugs

10th -13th

a2,a4 b1, b2 c2,c3 d1, d2

11. Anticancer drugs a2,a4 b1, b2 c2, c3 d1, d2

12. Antiviral drugs and anthelmintics a2,a4 b1, b2 c2,c3 d1, d2

Name Signature

Course Coordinator: Prof. Dr. Hassan A. El-Kashef

Head of Department: Prof. Dr. Hassan A. El-Kashef


Faculty of Pharmacy


Delta University



35

OTC Abuse 1. Basic Information:

Course title: Over the counter medication abuse

Course code: PB 435

Department: Pharmacology and biochemistry


Faculty: Pharmacy


Academic level: 4th level Fall semester 2016/2017

Specialization: Compulsory health and environmental course

Prerequisite: None



2. Course Aims:

2.1. Introduce the students to the basic concepts of drug abuse

2.2. Provide the student with the necessary knowledge about the different classes of OTC drugs

susceptible to abuse and the major signs and symptoms of drug abuse.

2.3. Provide the student with the information about the driving forces and the different reasons of

drug abuse




A16 a1. Recognize the toxic profile of various drugs.

a2. Define the symptoms and measures of prevention of drug misuse.



B15 b1. Estimate health hazards concerning drug abuse, misuse and exposure to toxic agents.



C9 c1. Raise public awareness on rational use of drugs and social health hazards of drug abuse

and misuse.



D1 d1. Communicate effectively with patients.

Faculty of Pharmacy


Delta University



36

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1. Introduction to drug abuse 2

2. Cough suppressant (Dextromethorphan) 2

3. Decongestant (Pseudoephedrine) 2

4. Pain reliever Acetaminophen (or Paracetamol) (NSAIDs) Ibuprofen

and Aspirin

2

5. Antihistamine (Dimenhydrinate, Diphenhydramine) 2

6. Diet pills abuse ,Laxative , 2

7. Mid-Term exam

8. Caffeine abuse 2

9. Anxiolytic and Hypnotics 2

10. Abuse of opiate Abuse of opiate 2

11. Abuse of anabolic steroids 2

12. Abuse of cocaine 2

13. Abuse of amphetamine 2

14. Final Exam

15. 24


5.1. Lectures

5.2. Assignments



1. Mid-Term Exam

& course work to assess knowledge, understanding, intellectual skills and general skills



confidence







Faculty of Pharmacy


Delta University



37



Final-Term Exam 65%

Oral Exam 10%

Total 100%


No. Reference Type

1. Abusing Over-the-Counter Drugs: Illicit Uses for Everyday

Drugs (Illicit and Misused Drugs) by Kim Etingoff 2012 Textbook



week

ILOs

knowledge

and

understanding

intellectual

skills

professional

and practical

skills

general and

transferable

skills

1. Introduction to drug abuse 1. a1 b1 c1

2. cough suppressant

(Dextromethorphan) 2. a1,a2 b1 c1 d1

3. Decongestant

(Pseudoephedrine) 3.

a1,a2

b1 c1 d1

4.

pain reliever Acetaminophen

(or Paracetamol) (NSAIDs)

Ibuprofen and Aspirin

4. a1,a2 b1 c1 d1

5.

antihistamine

Dimenhydrinate

Diphenhydramine

5. a1,a2 b1 c1 d1

6. Diet pills abuse ,Laxative 6. a1,a2 b1 c1 d1

7. Caffeine abuse 8. a1,a2 b1 c1 d1

8. Anxiolytic and Hypnotics 9. a1 b1 c1 d1

9. Abuse of opiate 10. a1,a2 b1 c1 d1

10. Abuse of anabolic steroids 11. a1,a2 b1 c1 d1

11. Abuse of cocaine 12. a1,a2 b1 c1 d1

12. Abuse of amphetamine 13. a1,a2 b1 c1 d1

Name Signature

Course Coordinator: Dr. Eman Mahmoud

Head of Department: Prof. Dr. Hassan El Kashef


http://www.amazon.com/Kim-Etingoff/e/B001JS33EC/ref=sr_ntt_srch_lnk_1?_encoding=UTF8&qid=1264605410&sr=8-1

Faculty of Pharmacy


Delta University



38

Toxicology 1. Basic Information:

Course title: Toxicology

Course code: PB 421



Faculty: Pharmacy


Academic level: 4th level Spring Semester 2016-2017


Prerequisite: Pharmacology 2



2. Course Aims:

2.1 Understand the basic principles and the different disciplines of toxicology.

2.2 Gain knowledge regarding first aid measures, the supportive measures, therapeutic

interventions, specific antidotes as general guidelines of treatment modalities.

2.3 Know the mechanism of toxicity, toxicokinetics, clinical presentation, diagnosis and

medications indicated and contraindicated in the treatment of toxicity of common drugs and

chemical groups.

2.4 Recognize the serious consequences of exposure to therapeutic drugs, environmental and

occupational chemicals.




A1 a1. Describe the general principles of poisoning management; explain actions, interactions,

uses and toxicity of certain medications.

A16

a2. Illustrate clinical features of diseases and appropriate medical interventions in

emergencies, with stress on some genetic abnormalities and toxicology of addiction.

a3. Find toxic profile of various drugs and other xenobiotic including sources,

identification, symptoms, management, control and first aid measures.

Faculty of Pharmacy


Delta University



39



B11

b1. The student can differentiate between different toxic agents regarding their

symptoms, as well as their main lines of toxicity treatment.

b2. Apply the knowledge of patient stabilization and antidotes in management of toxicity

cases.

B15 b3. Assess drug interactions and adverse drug reactions.

b4. Analyze, evaluate and interpret clinical cases of toxicity.



C7 c1. Assess risks concerning drug-drug interactions, adverse reactions and toxicity profiles.

C21

c2. Conduct the safe and effective use of drugs on patients while managing the toxicity

condition.

c3. Analyze minor illnesses from toxicity cases requiring prompt medical intervention.



D1 d1. Provide good advice in poisoning cases.

D3 d2. Identify the problem affecting community or a subject in clinical toxicology, with trial

of solving by teamwork.

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1. Introduction 2

2. Mechanisms of toxicity 2

3. Air, soil and water pollution 2

4. Air, soil and water pollution 2

5. Metal Toxicity 2

6. Target organ Toxicity 2

7. Mid-Term exam

8. Liver Toxicity 2

9. Kidney Toxicity 2

10. pulmonary Toxicity 2

11. Neurotoxicity 2

12. Carcinogenesis 2

13. Mutagenesis 2

Faculty of Pharmacy


Delta University



40

14. Final Exam

15. 24


5.1. Lectures

5.2. Seminars





confidence



confidence



Assessment 2 Quiz 10th wek




Mid-Term Exam & course work 25 %


Oral Exam 10 %

Total 100%


No. Reference type

1. Casarett & Doull's Toxicology: The Basic Science of Poisons, by

Curtis Klaassen. (McGraw-Hill Education; 8th edition, 2013 textbook

2.

www.pubmed.com

http://toxnet.nlm.nih.gov/query.fcgi

http://www.ncbi.nlm.nih.gov/entrez/

website

http://www.pubmed.com/

http://toxnet.nlm.nih.gov/

http://www.ncbi.nlm.nih.gov/entrez/

Faculty of Pharmacy


Delta University



41



week

ILOs

knowledge

and

understanding

intellectual

skills

professional

and

practical

skills

general and

transferable

skills

1. Introduction 1 a1, a2 b4, b1, c2, c3

2. Mechanisms of toxicity 2 a1, a3 b4,b2 c1 d1

3. Air, soil and water

pollution 3-4 a3, a2 b1 c2, c3 d2

4. Metal Toxicity 5 a3 b1,b2, b3 c1, c3 d2

5. Target organ Toxicity 6 a2, a3 b1-b4 c1 d2

6. Liver, Kidney, pulmonary,

Toxicity 8-10 a1,a2, a3 b1-b4 c1, c3 d1, d2

7. Neurotoxicity 11 a1,a2, a3 b1-b4 c1, c3 d1

8. Carcinogenesis 12 a1,a2, a3 b2, b3,b4 c1,c2 d1

9. Mutagenesis 13 a1,a2, a3 b2, b3,b4 c1 d1

Name Signature

Course Coordinator: Dr. Hamdy Ghoneim



Faculty of Pharmacy


Delta University



42

Clinical Biochemistry 1. Basic Information:

Course title: Clinical Biochemistry

Course code: PB 422



Faculty: Pharmacy


Academic level: 4th level Spring Semester 2016/2017


Prerequisite: Biochemistry-2



2. Course Aims:

By the end of this course, a successful student should be able to demonstrate an understanding of

the principles of laboratory analysis and the application of analyses to human disease. Also, he

should be able to explain the concept of the reference range and its predictive value and the

limitations thereof and to discuss the use of a range of routine tests in the diagnosis of and follow

up of treatment of a variety of disease states.




A1 a1. Identify the medical principles of Clinical Biochemistry

A11

a2.

Recognize the differences between hormones as adrenal gland hormones, thyroid gland

hormones, gonads hormones, insulin hormone and tumor markers in health and disease

state

a3. Define the central role of liver and kidney disorders and their diagnosis by biochemical

tests



B3 b1. Determine the impact of clinical biochemistry results and be able to diagnose and manage

common medical conditions

B14 b2. Evaluate biomedical information concerning biochemical diagnostic tests

B18 b3. Correlate the liver and kidney functions with clinical data

B21 b4. Interpret the different disorders of endocrine glands and hormonal profile

Faculty of Pharmacy


Delta University



43



C1 c1. Utilize the proper medical terminology to communicate with other health care

professionals

C11 c2. Conduct research studies chosen on Endocrinology and kidney functions



D3 d1. Work effectively as a part of a team to perform the required tasks


4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1. Endocrine system: overview 2

2. Pituitary gland and their disorders 2

3. Thyroid gland and their disorders 2

4. Reproductive system : Male and female and their disorders 2

5. Male and Female infertility : hormonal profile and semen analysis 2

6. Kidney diseases 2

7. Mid-Term exam

8. Kidney function tests 2

9. Liver biochemical role and their disorders 2

10. Liver function tests 2

11. Clinical Enzymology 2

12. Tumor markers 2

13. Diabetes mellitus 2

14. Final Exam

15. 24


5.1. Lectures

5.2. Research in library and web.

5.3. case study and seminars

Faculty of Pharmacy


Delta University



44





confidence


confidence









Mid-Term Exam, course work & case study 25%

Final-Term Exam 65%

Oral Exam 10%

Total 100 %


No. Reference type

1.

- Tietz Fundamentals of Clinical Chemistry and Molecular

Diagnostics by Carl A. Burtis, and David E. Bruns, editors. (St.

Louis, MO: Elsevier Saunders; 7th edition, 2014).

- Bishop Textbook for Clinical Chemistry principles, techniques

and correlations by Michael L. Bishop , Edward P. Fody and

Larry E. Schoeff (Lippincott Williams & Wilkins; 7th edition,

2013).

- Clinical biochemistry: An Illustrated Colour Text, By Allan

Gaw Michael Murphy Rajeev Srivastava Robert Cowan Denis

O'Reilly. (Churchill Livingstone; 5th edition, 2011)

textbook



Faculty of Pharmacy


Delta University



45



week

ILOs

knowledge

and

understanding

intellectual

skills

professional

and

practical

skills

general and

transferable

skills

1. Endocrine system: overview 1 a1,a2 b1,b2,b3 d1,d2

2. Pituitary gland and their

disorders 2 a1,a2 b1,b2,b3 c1 d1,d2

3. Thyroid gland and their

disorders 3 a2,a3 b1,b2,b4 c1 d1,d2

4.

Reproductive system : Male

and female and their

disorders

4 a2,a3 b1,b2,b4 c1 d1,d2

5.

Male and Female infertility :

hormonal profile and semen

analysis

5 a2,a3 b1,b2,b4 c1 d1,d2

6. Kidney diseases 6 a2 b1,b2,b4 c1 d1,d2

7. Kidney function tests 8 a3 b1,b2,b4 c2 d1,d2

8. Liver biochemical role and

their disorders 9 a2,a3 b1,b2,b4 c1,c2

d1,d2

9. Liver function tests 10 a2,a3 b1,b2,b4 c2

d1,d2

10. Clinical Enzymology 11 -- b1,b2 c1 d1,d2

11. Tumor markers 12 a2 b1,b2 c1 d1,d2

12. Diabetes mellitus 13 a2

b1,b2,b3 c1 d1,d2

Name Signature

Course Coordinator: Dr. Samouel Tanas



Faculty of Pharmacy


Delta University



46

Biostatistics 1. Basic Information:

Course title: Biostatistics

Course code: PB 542



Faculty: Pharmacy


Academic level: 5th level Spring semester 2016/2017


Prerequisite: None



2. Course Aims:

This course is designed to give student the ability in problem solving, experimental design, and

evaluation of data of clinical trials involving pharmacotherapy, data collection and presentation of

data mathematically. The course gives an idea about estimation of the drug’s effects on different

body organs and tissues, also provide the students with the basic principles of evaluation of the

results of experiments.




A1 a1. Describe the principles of basic in the field of statistics and biological assay.

A17

a2. Distinguish methods of statistical analysis and pharmaceutical calculations in an

efficient manner for handling data.

a3. Identify methods of drug screening and bioassay on experimental animals to estimate

the potency of drugs and for biological standardization.



B13

b1. Analyze critically the data derived from laboratory and clinical observations and

measurements.

b2. Compare the potency of the test and standard preparations used in bioassay procedures

based on the statistical results.

b3. Outline the main steps in screening and biological standardization of different

substances based on their physiological function or toxic effects.

Faculty of Pharmacy


Delta University



47



C11

c1. Discriminate between various experimental models to select the best one used for

biological assay.

c2.

Design complete experimental protocols for biological standardization of different

compounds, beginning from problem-recognition to statistical analysis and evaluation

of results and findings.



D3 d1. Work effectively within a team.

D4 d2. Collect, evaluate and present data in accordance with standard statistical methods.

D11 d3. Generate effective and reasonable solutions for rising problems based on the available

information.

4. Contents:

4.1.Lectures:

Week

No. Topics

No. of

hours

1. Introduction of statistics 2

2. Introduction of statistics 2

3. Student Paired T-test 2

4. Student unpaired T-test 2

5. Methods used to minimize variability in biological assay blind screening. 2

6. Application (exercise) 2

7. Mid-Term exam

8. Chi-X2 test 2

9. ANOVA test 2

10. Measures of mortality and morbidity 2

11. Bioassay and screening of autonomic acting drugs and skeletal muscle relaxants 2

12. Bioassay and screening of autacoid and anti-inflammatory drugs 2

13. Bioassay and screening of cardiac Glycosides and antihypertensive drugs 2

14. Final Exam 24

15.


5.1. Lectures

5.2. Assignments and homework

Faculty of Pharmacy


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48



1. Written exam To assess the knowledge, understanding and intellectual skills of students, in

midterm or final examination to the studied topics of the course.

2. Course work To assess intellectual, general, transferrable and Professional skills.


4. Oral exam To assess knowledge, understanding, intellectual skills, general skills and

confidence


Assessment 1 Mid-term 7th weeks

Assessment 2 Quiz 10th weeks

Assessment 3 Oral 14, 15th weeks

Assessment 5 Written 14, 15th weeks


Mid-Term Exam & Course work 25 %


Oral Exam 10 %

Total 100%


No. Reference type

1.

1.1. Drug Discovery and Evaluation: Pharmacological Assays by Franz J. Hock

(Editor), (Springer; 4th edition, 2016).

1.2. Drug Discovery and Evaluation: Pharmacologic assays by Vogel and Vogel

(Springer; 3rd edition, 2008).

1.3. Drug Discovery and Evaluation: Methods in Clinical Pharmacology by

Vogel, Maas and Gebauer (Springer; 1st edition, 2011)

textbooks

2. www.Pubmed.com website



week

ILOs

knowledge

and

understanding

intellectual

skills

professional

and

practical

skills

general and

transferable

skills

1. Introduction of statistics 1,2 a1,a2 b1 c2

2.

Student Paired T-test,

Student unpaired T-test,

Methods used to minimize

variability in biological

assay blind screening.

3-5 a2 b1,b2 c2 d2

https://www.amazon.com/s/ref=dp_byline_sr_book_1?ie=UTF8&text=Franz+J.+Hock&search-alias=books&field-author=Franz+J.+Hock&sort=relevancerank


Faculty of Pharmacy


Delta University



49

3. Application (exercise) 7 a2 b1,b2 c1,c2 d1,d2, d3

4.

Chi-X2 test, ANOVA test,

Measures of mortality and

morbidity

8-10 a2 b1,b2 c2 d1, d2

5.

Bioassay and screening of

autonomic acting drugs

and skeletal muscle

relaxants

11 a3 b2,b3 c1,c2 d2, d3

6.


autacoid and anti-

inflammatory drugs

12 a3 b2,b3 c1,c2 d2, d3

7.


cardiac Glycosides and

antihypertensive drugs

13 a3 b2,b3 c1,c2 d2, d3

Name Signature

Course Coordinator: Dr. Hamdy Ghoneim



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