country study: medicinal products in the czech republic
TRANSCRIPT
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COUNTRY STUDYMedicinal products in the Czech Republic Analysis of registered products by ATC code Date: December 30, 2016
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CZECH REPUBLICNumber of products per ATC code by registration status Graphics created in IBM Watson
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Approved treatments by ATC code
N03AX16Pregabalin1190 approved drugs
Number of registrations includes all strengths and dosage forms
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Approved treatments by ATC code
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Approved Cancelled Nutraceuticals Product after change (6 months)Specific therapeutic program app. Suspended
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ALIMENTARY TRACT AND METABOLISM (A)
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Alimentary tract: A01, A02 and A03 Stomatological preparations
Acid-related disorders: antacids, gastric-oesophageal reflux,
peptic ulcer
Drugs for functional GIT disorders: antispasmodics in combination with
psycholeptics
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Alimentary tract: A04, A05 and A06 Anti-emetics and
antinauseantsBile and liver
therapy Drugs for constipation
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Alimentary tract: A07, A08 and A09 Anti-diarrheals, intestinal anti-inflammatory
and intestinal anti-infective agents
Ant
i-obe
sity
dru
gs
Dig
estiv
es, i
ncl.
enzy
mes
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Alimentary tract and metabolism: A10 (drugs used in diabetes)
metformin
glimepiride
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Alimentary tract and metabolism: A11, A12, A14Vitamins
Ana
bolic
ste
roid
sMineral supplements
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Alimentary tract and metabolism: A16
(other alimentary tract and metabolism products)
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BLOOD AND BLOOD FORMING ORGANS (B)
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Blood and blood forming organs: B01
(anti-thrombotic agents)
clopidogrel
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Blood and blood forming organs: B01 Anti-hemorhagics: anti-fibrinolytics, vitamin K and other hemostatics
Anti-anemic preparations: iron, B12, folate, other
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Blood and blood forming organs: B05, B06 Blood substitutes and perfusion solutions Anti-anemic
preparations: iron, B12,
folate, other ElectrolytesHypertonic solutions
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CARDIOVASCULAR SYSTEM (C)
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Cardiovascular: C01, C02Cardiac glycosides, antiarrhythmic drugs class I and III, cardiac
stimulants, vasodilatators for cardiac use, other cardiac preparations Antihypertensives
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Cardiovascular: C03, C04, C05Vasoprotectives:
agents for the treatment of hemorrhoids, anal fissures, and varices, and capillary stabilizing agents
Perip
hera
l va
sodi
lata
tors
Diuretics
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Cardiovascular: C07 and C08Antiarrhythmic drugs:
Calcium channel blockers Antiarrhythmic drugs: Betablockers
metoprololbisoprolol
carvedilol amlodipine
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Cardiovascular: C09 (ACE inhibitors)Pe
rindo
pril
Ram
ipril
Perin
dopr
il +
am
lodi
pine
Ram
ipril
+ a
mlo
dipi
neLo
sarta
n Irb
esar
tan
Telm
isar
tan
Vals
arta
n +
diur
etic
sTe
lmis
arta
n +
diur
etic
s
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Cardiovascular: C10 (lipid modifying agents)C10AA HMG CoA reductase inhibitors:• C10AA05 – atorvastatin • C10AA07 – rosuvastatin
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DERMATOLOGICALS (D)
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Dermatological agents: D01, D02, D03, D04, D05, D06
Emol
lient
s an
d pr
otec
tives
Antifungals
Trea
tmen
t of w
ound
s an
d ul
cers
Ant
ipru
iritic
s
Ant
ipso
riatic
s
Antibiotics and topical chemotherapeutics
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Dermatological agents: D07, D08, D09, D10, D11
Corticosteroids for dermal use
Antiseptics, disinfectants
Med
icat
ed d
ress
ings Anti-acne
preparationsOther
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GENITO-URINARY AGENTS AND SEX HORMONES (G)
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Genito-urinary agents and sex hormones: G01, G02, G03
Gynecological anti-infectives and
anti-septics
Other gynecological
agents
Sex hormonesG03A – hormonal contraceptives for systemic use
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Genito-urinary agents and sex hormones: G03Sex hormones and modulators of the genital system: • hormonal contraceptives for systemic use• androgens, estrogens, progestogens• gonadotropins and other ovulation stimulants• antiandrogens
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Genito-urinary agents and sex hormones: G04(urologicals)
Solif
enac
in
Sild
enaf
ilTa
dala
fil
Tam
sulo
sin
Fina
ster
ide
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SYSTEMIC HORMONAL PREPARATIONS (H)
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Systemic hormonal preparations: H
Pituitary and hypothalamic hormones and their analogues
Corticosteroids for systemic use
Thyroid hormones
Calcium homeostasis
Panc
reat
ic h
orm
ones
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ANTIINFECTIVES FOR SYSTEMIC USE (J)
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Antibacterials for systemic use: J01J01A – Tetracyclines J01B – Amphenicols J01C – Beta-lactams, penicillines J01D – Other beta-lactams J01E – Sulfonamides and trimetoprim
J01F – Macrolides, lincosamides, streptogramines J01G – Aminoglycosides J01M – Quinolones J01R – Combinations J01X – Other
Linezolid
Amoxicillin + enzyme inhibitor
Cefuroxime
Clarith
romyc
ine
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J02 – Antimycotics for systemic use J04 – AntimycobacterialsJ05 – Antivirals
Linezolid
Antiinfectives for systemic use
Fluconazole
Voriconazole
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Antiinfectives for systemic use: J06, J07
Immune sera and immunoglobulins Vaccines
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ANTIINEOPLASTICS AND IMMUNOMODULANTS (L)
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Anti-neoplastic agents: L01Alkylating agents Anti-metabolites Plant alkaloids Cytotoxic
antibioticsMethotrexate
BendamustineCapecitabine
Temozolomide
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Anti-neoplastic AgentsL01X (Other)
Imatinib
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Antineoplastic and immunomodulating agentsEndocrine (L02) & Immunostimulants (L03)
Bica
luta
nide
Anas
trozo
leLe
trozo
le
pegi
nter
fero
n al
fa-2
b
filgr
astim
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Immunosuppressants: L04Selective immunosuppressants TNF-ɑ
inhibitorsInterleukin inhibitors
Cal
cine
urin
inhi
bito
rs
Other
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MUSCULO-SKELETAL SYSTEM (M)
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Musculo-skeletal system: M01, M02, M03Anti-inflammatory, anti-rheumatic agents Topical muscle
and joint pain Muscle relaxants
Ibuprofen
Diclofenac Etoricoxib
Diclofenac
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Musculo-skeletal system: M04, M05, M09Anti-gout
preparationsDrugs for the treatment of bone diseases Other drugs for
musculo-skeletal disorders
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NERVOUS SYSTEM (N)
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Nervous system: Anesthetics (N01) and Analgesics (N02)
Oxy
codo
ne
Oxy
codo
ne +
nal
oxon
e
Fent
anyl
Bup
reno
rphi
ne
Tram
adol
Ta
pent
adol
Tr
amad
ol +
com
bina
tions
Par
acet
amol
P
arac
etam
ol +
com
b.
Sum
atrip
tan
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Nervous system: Anesthetics (N01) and Analgesics (N02)
Oxy
codo
ne
Oxy
codo
ne +
nal
oxon
e
Fent
anyl
Bup
reno
rphi
ne
Tram
adol
Ta
pent
adol
Tr
amad
ol +
com
bina
tions
Par
acet
amol
P
arac
etam
ol +
com
b.
Sum
atrip
tan
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Nervous system: Anti-epileptics (N03) and Anti-Parkinson drugs (N04)
Lam
otrig
ine
Topi
ram
ate
Gab
apen
tinLe
vetir
acet
am
Pre
gaba
lin
Levo
dopa
+ d
ecar
boxy
lase
in
hibi
tor +
CO
MT
Pra
mip
exol
eR
opin
irole
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Nervous system: Psycholeptics (N05)Antipsychotics Anxiolytics Hypnotics and
sedatives
Arip
ipra
zole
Que
tiapi
neO
lanz
apin
e
Ris
perid
one
Zolp
idem
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Nervous system: N06Antidepressants Psychostimulants
NootropicsAnti-ADHD drugs
Anti-dementia drugs
• AB04 – citalopram• AB06 – sertraline • AB10 – escitalopram • AX11 – mirtazapine • AX16 – venlafaxine • AX21 – Duloxetine
Don
epez
il
Mem
antin
e
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Nervous system: N07Pa
rasy
mpa
tom
imet
ics
Addictive disorders Anti-vertigo drugs Other
Nic
otin
e
Bet
ahis
tine
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ANTIPARASITICS (P)
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Antiparasitics, insecticides and repellents: P
P01 Antiprotozoals P02 Anthelmintics P03 Ectoparasiticides
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RESPIRATORY SYSTEM (R)
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Respiratory: R01 and R02
Nasal preparations Throat preparations
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Respiratory:Drugs for obstructive airway diseases (R03)
Montelucast
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Respiratory: R05, R06 and R07 Cough and cold preparations Antihistamines for systemic use Other
Levocetirizine Desloratidine
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SENSORY ORGANS (S)
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Sensory organs: Ophthalmologicals (S01), Otologicals (S02) and combinations (S03)
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VARIOUS (V)
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Various: V01, V03, V04 and V06Allergens All other therapeutic products
Dia
gnos
tic p
rodu
cts
Gen
eral
nut
rient
s (n
utra
ceut
ical
s)
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Various: All other non-therapeutic products (V07), Contrast media (V08), and Diagnostic radiopharmaceuticals (V09)
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Various: Therapeutic radiopharmaceuticals (V10), and all other (V11 and V12)
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ARETE-ZOE, as a consultancy, provides solutions to complex problems in the high stakes and high consequence environment of Global Pharmaceuticals, including clinical research, healthcare informatics, and public health. We blend established, Pharma sector methodologies, innovation, and adaptations/transfers from other sectors to identify and resolve consequential practices that pose risk and often result in avoidable patient casualty. However, we are specifically, not a patient advocacy group but believe in optimizing organizational effectiveness and that smart business is agile, competitive and profitable, while intrinsically safe, secure, and resilient. We work within a global context because transnational interests influence national circumstances and choices at point of prescription.
ARETE-ZOE, provides full spectrum organizational and operational risk management consultancy. Our published materials provide a glimpse of some aspects of our services to demonstrate both knowledge and ongoing participation within the Pharmaceutical Industry. Our analysis and consultancy includes all channels of misuse, diversion, counterfeiting and illicit exploitation of pharmaceuticals, medical devices, and precursor chemicals. Our advisement is to manufactures, jurisdictional entities, insurers, legislators, litigators, patients, and health care providers. This scope also frequently segues into the nexus of crime and terrorism as significant influencers that undermine sector integrity differentiated from other criminal activity. Obviously, vulnerability assessment, information collection management and intelligence production supporting decision-making for risk reduction and interventions are routinely within the scope of our services as well as design and implementation of operational control measures.
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