Countries in Europe where combined vaccines are licenced

Pierre Van Damme, MD, PhD

University of Antwerp

Availability of combined vaccines in Europe, 2000

• DTPa-HepB (4):– Greece (Uni-Inf)– Italy (Uni-Inf)– Switzerland– Ukraine (Uni-Newb)

• DTPa-Hib (7)– Austria (UniInf)– Germany (UniInf)– Gibraltar– Slovenia (Child)– Spain (UniNewb)– Switzerland– United Kingdom (2

manuf.)

Availability of combined vaccines in Europe, 2000

• DTPa-IPV-Hib (12):– Austria – Belgium (Uinf)– Croatia – France (2) (Uinf)– Germany (2) (Uinf)– Greece (Uinf)– Israel (Unewb)– Italy (2) (Uinf)– Ireland– Spain (2) (Unewb)– Sweden (2)– Switzerland

• DTPa-IPV (7):– Austria– France (2 manuf.) (Uinf)– Switzerland – Belgium (2 manuf.)

(Uinf)– Italy (Uinf)– Germany (Uinf)– Ireland

Availability of combined vaccines in Europe, 2000

• DTPa-hepatitis B-IPV-Hib (7):– Austria (UniInf)– Croatia– Germany (2) (UniInf)– Greece (UniInf)– Italy (°2001) (2) (UniInf)– Spain (°2001) (2) (UniNewb)– Switzerland (2)

Availability of combined vaccines in Europe, 2000

• Greece: UniInf– DTPa-HB– DTPa-IPV-Hib– DTPa-HB-IPV-Hib– HB-Hib

• Italy: UniInf– DTPa-HB– DTPa-IPV– DTPa-IPV-Hib (2)– DTPa-HB-IPV-Hib (2)– HB-Hib

• Switzerland: Ado– DTPa-HB– DTPa-Hib– DTPa-IPV-Hib– DTPa-HB-IPV-Hib (2)

• Germany: UniInf– DTPa-Hib– DTPa-IPV– DTPa-IPV-Hib (2)– DTPa-HB-IPV-Hib (2)– HB-Hib

Availability of combined vaccines in Europe, 2000

• Croatia: Ado– DTPa-IPV-Hib– DTPa-HB-IPV-Hib

• Spain: UniInf– DTPa-Hib– DTPa-IPV-Hib (2)– DTPa-HB-IPV-Hib (2)

Availability of combined vaccines in Europe, 2000

• Combined vaccines appear to be licensed in a certain country, according to: – the vaccine history in the country– the antigens in the existing vaccination

programmes• e.g. no IPV combination in the UK (use OPV)• e.g. no hepB combination in UK or Sweden

• Specific combination according to what is already on the market (as a complement of):– e.g. Procomvax (HB+Hib) in Austria, Germany,

Greece and Italy