Corporate Presentation

OTCQB:VYCO

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Safe Harbor Statement

Information in this document constitute forward-looking statements or statements which may be deemed or construed to be forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The words "forecast", "anticipate", "estimate", "project", "intend", "expect", "should", "believe", and similar expressions are intended to identify forward-looking statements. These forward-looking statements involve, and are subject to known and unknown risks, uncertainties and other factors which could cause VYCOR MEDICAL's actual results, performance (financial or operating) or achievements to differ from the future results, performance (financial or operating) or achievements expressed or implied by such forward-looking statements. The risks, uncertainties and other factors are more fully discussed in VYCOR'S SEC filings. All forward-looking statements attributable to VYCOR herein are expressly qualified in their entirety by the abovementioned cautionary statement. VYCOR disclaims any obligation to update forward-looking statements contained in this estimate , except as may be required by law. The recipient acknowledges that Vycor Medical, Inc. is a publicly traded company. Recipient acknowledges that any confidential information constituting material nonpublic information that Vycor Medical, Inc. provides to the recipient is being provided to the recipient in reliance upon the agreement that the information will remain confidential. By accepting this material, the recipient acknowledges that it is aware of the applicable requirements of the federal securities laws relating to material non-public information and trading in securities of Vycor Medical, Inc.

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Vycor Medical is focused on providing the medical community with innovative and superior surgical and therapeutic solutions

Through our two business units, Vycor Medical and NovaVision, we are pursuing minimal or non-invasive approaches to treating brain disorders or injury

Our portfolio of FDA-cleared medical solutions are changing and improving lives every day

Technology validated by numerous independent third party practitioners and by clinical studies

Robust patent portfolio: 57 patents and 13 pending

Who We Are

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Our Two Product Lines

Most comprehensive, commercially available and clinically-supported line of complementary therapies: Visual Restoration Therapy® (VRT): the only FDA-cleared therapy for the restoration of vision loss as the result of stroke or brain damage NeuroEyeCoach™: helps patient compensate for vision disorders as a result of stroke or brain damage

ViewSite™ Brain Access System (VBAS) • VBAS is a revolutionary neurosurgical device used

to retract and gain access to targets within the brain

• Allows access to tumors or other pathologies, or physical objects, like bullets or shrapnel fragments

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NovaVision’s suite of complementary therapies helps patients with vision disorders resulting from stroke or brain injury

Similar to recovery from motor deficits after brain injury, where repetitive stimulation has proven effective in recovery of patient functions such as movements of lower limbs, systematic repetitive visual training can lead to improved visual sensitivity and function

By stimulating the adjacent neuronal pathways, they assume some of the functionality that had been lost, effectively creating a bypass mechanism

NovaVision

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8 Million Stroke Survivors in the U.S. – 30% or 2.4 Million Suffer from Vision Disorders1 $13 Billion Global Market Opportunity1

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Multi-Billion Dollar Market Opportunity for NovaVision

US $2B

Europe $2B ROW

$9B

Suffer from Vision Disorders

30%

• Vision loss from stroke and traumatic brain injury (TBI) has been largely unaddressed

• Every 40 seconds someone has a stroke • Every year 600,000 people suffer from vision disorders due

to stroke or TBI

• NovaVision: ~$4bn in the US/Europe, ~$13bn globally • Stroke associations & support groups total over 6,000 in the

US, powerful disseminators • Most patients touch a stroke rehab center/clinic

1) Company estimate

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Recently launched Internet-delivered VRT and NeuroEyeCoach therapy suite • VRT the only FDA cleared therapy for restoration of this type

of vision loss • NeuroEyeCoach also FDA registered

Validated by Healthcare Professionals • HealthSouth has approved VRT diagnostic and

NeuroEyeCoach to be offered in its 100+ rehab hospital network, the largest in the US

• 200+ prescribing physicians in the US, 38 partners clinics in Europe

No clinically supported alternative • No other real competitors – Sight Science the largest,

purchased in 2012 • Fully patent-protected: 41 granted and 2 pending patents

An Unrivaled Approach…

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Clinically Demonstrated to Restore and Make the Most of Remaining Vision VRT: 15 years of research, 20 clinical studies including a 302 patient

study in which notable improvements were seen in over 70% of the patients. Prescription-based, bespoke “at home” therapy — Not an App

NeuroEyeCoach: based on empirical evidence gained from several decades of research and 14 studies on a total of 591 patients. Oct 2016 study concluded: “NeuroEyeCoach can be used as an effective rehabilitation tool to develop compensatory strategies in patients with visual field deficits after brain injury” and that NeuroEyeCoach can be viewed as being the first evidence-based, vision-specific, clinical gold standard registered medical device accessible to patients at home or in clinical settings.

Patient Success Stories Substantial body of testimonials from enthusiastic patients whose

lives were changed Carol Urban, a former patient, interviews aired on 200+ US radio

stations

…And it Works

“VRT makes a world of difference. Every day I feel like l see a little better. This would not be possible without NovaVision.

This is second time NovaVision saved my eye sight when no-one else would help. Your program is a life saver I can smile again.” - Annette, a VRT and

NeuroEyeCoach patient, Aug. 2015

“We do not need a new brain, but innovative methods of treatment to overcome the functional consequences of brain injury” - Prof. Josef Zihl

NovaVision Scientific Advisor

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Impact on daily life can be dramatic, enabling a patient to live at home alone,

cross the road unaided, shop, read and even drive

Pre-VRT Post-VRT

“My vision began coming back after the first month of therapy…I passed my driving test, can read normally, and enjoy driving my boat on the lake…my life is back to normal.” – Stroke survivor & VRT patient

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An Important Therapy for Daily Life

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Patients Professionals

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Multi-Faceted Growth Strategy

Stroke Associations & Support Groups • Over 6,000 in the US, powerful disseminators;

identified, mailing and marketing to them • Partnered with American Stroke Association

Stroke Rehabilitation Centers and Clinics Most patients touch a rehab center/clinic • VRT Diagnostic model • NeuroEyeCoach Center model • Both approved by HealthSouth

NovaVision’s Multi-faceted Marketing Strategy to Drive Awareness & Adoption Into Key Interest Groups

Physicians and Other Healthcare Professionals VRT is a prescription-only therapy • NovaVision referral program: >200 prescribers • Pro Physician Model • Website, in-bound and out-bound marketing

Direct to Patients 80% of our enquires come through our website • New website to drive traffic, capture info • In-bound/out-bound marketing • Multi-channel digital/social media • Blogs, media placements, success stories

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ViewSite Brain Access System

“It is the ideal system for providing deep brain access through a smaller incision.”

-Leading Neurosurgeon

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VBAS is a Step Change Improvement. Incumbent Technology Hasn't Changed in Over 50 Years 12

• Less brain tissue damage • Less invasive: requires smaller opening • Better access • Better visibility • Self-contained working channel • Reduced operating and recovery time

The Future Standard of Care

Old Blade/Ribbon Retractor Technology

VBAS Next Generation Technology

Allows for use in procedures previously considered inoperable, saving lives

VS.

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VBAS Saves Lives

Previously Inoperable…Now Operable “Her case would have been inoperable via a traditional surgery, because she was taking Avastin®, which delays surgical wound healing. “The VBAS’ minimally invasive nature enabled the surgeon to gain access to the target through only a 3cm incision. “The patient was discharged uneventfully and there were no issues regarding her wound.”

– Daniel Prevedello, MD, Director of the Minimally Invasive Cranial Surgery Program, Ohio State University

Bullet fragment removal “We would not have attempted this without this technology. It’s very exciting”

– Narayan Sundaresan, MD, Chief Neurosurgeon at Lincoln Medical Center, NY, and Professor at Mount Sinai Hospital, NYC

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Large body of clinical papers and studies evidence VBAS’ clinical superiority and improved patient outcomes; including VBAS appearing on the cover of the prestigious Journal of Neurosurgery in March 2015

International presence with regulatory approvals in key international markets including Australia, Brazil, China, Europe, Japan and Russia

Technology protected by 16 granted and 11 pending patents in the U.S. and abroad

Patented, Validated & Approved Technology

Approved for Use in 202 Hospitals, including the Nation’s Leading Medical Centers

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Virtual Business Model Enables Vycor to Leverage Both Internal and Outsourced Partner Resources to Maximize Efficiency & Reduce Cost 15

Vycor operates upon “virtual outsourced” business model to focus its resources on product development and direct targeted marketing to physicians and hospitals

Manufacturing: outsourced to qualified sub-contract manufacturer

US sales: outsourced to 20 distributors with av. 4-5 reps each who are experts in the neurosurgical device space, have local presence and are in the OR daily

International sales and marketing: outsourced to leading distributors in each country/region focused on neurosurgical devices

Virtual Company: Reduces Cost

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Four-Part Growth Strategy

US Market Penetration • Well-defined market of 4,000 surgeons • Strengthening the distributor network • Broaden VBAS usage beyond “deep and difficult” • Focus on key teaching hospitals

Clinical data • Drives adoption and user acceptance, increases

revenues • 8 papers in 2015/16 alone • Moves VBAS up the hospital cost/benefit curve • Provides evidence of broader applicability

International • Target markets with patent protection and/or clear

regulatory path • Use distributors with experience in neurosurgical

devices • Focus on Brazil, larger European markets, Asia

New Product Development • VBAS provides platform for product extensions • Objective to broaden adoption and increase

applicability • VBASMini launched March 2016 • Adapting VBAS to be make it more easy to integrate

with IGS

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Peter Zachariou, CEO David Cantor, President Adrian Liddell, Chairman & CFO

Company Contacts Corporate Headquarters 6401 Congress Avenue Suite 140 Boca Raton, FL 33487

www.vycormedical.com

www.vycorvbas.com

www.novavision.com

www.sightscience.com

German Office Klausenerstr. 12 39112 Magdeburg, Germany

UK Office 214 Union Street, Aberdeen, AB10 1TL Scotland, UK

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Contact Us

Websites

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Appendix

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Peter Zachariou CEO & Director

David Cantor

President & Director

Adrian Liddell

Chairman & CFO

Steven Girgenti Director

Lowell Rush

Director

Dr. Oscar Bronsther

Director

Extensive operating experience over range of manufacturing businesses

Active investor in variety of companies and industries, both public and private, specializing in capital formation/raising and development companies

22 years experience of Investing in, raising money for and providing strategic advice to growth companies across a broad range of sectors

Investment Banking (Citigroup, Donaldson, Lufkin & Jenrette, Lehman Brothers)

Over 30 years of strategic, corporate and financial advisory and company investment

Private equity (Phoenix Equity Partners); Investment Banking (Citigroup, Donaldson, Lufkin & Jenrette, Lehman Brothers)

Chartered Accountant

Pharmaceutical and healthcare executive with 45 years experience

Managing partner of Medi-Pharm consulting, providing strategic advice to healthcare companies

Former President and CEO of DermWorx and former Chairman of Ogilvy Healthworld

CEO of Direct Incite

Former COO of Cosmetic Dermatology,CFO of Bijoux Terner and Little Switzerland, and has held operational and financial roles at SunGlasses Hut, Burger King and Knight-Ridder. CPA and MBA

Clinical professor at George Washington Univ. and Director of Transplant Services at Kaiser Permanente Medical Group. Previously Associate Prof. at Univ of Rochester, Univ of Pittsburg and Univ. of California San Diego

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Executive Management & Board of Directors

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Scientific Advisory Boards

Dr. David Langer

Dr. Konstantin Slavin

Dr. Ezriel Kornel

Prof. Arash Sahraie

Alvaro Pascale-Leone, MD/PhD

Jason S. Barton, MD

Joseph Zihl, MD

Jose Romano, MD

Vycor Vycor Vycor NovaVision NovaVision NovaVision NovaVision NovaVision

Director of Cerebrovascular Neurosurgery at St. Luke’s-Roosevelt, Beth-Israel and Long Island College Hospitals (New York, NY)

University of Illinois at Chicago (Chicago, IL); Alexian Neuroscience Center (Elk Grove Village, IL); Director of Illinois Gamma Knife Center

Director, Institute for Neurosciences at Northern Westchester Hospital Center (Mount Kisco, NY); President-elect New York State Neurosurgical Society; Board of Directors, Medical Liability Mutual Insurance; Director for Center Neurochiropractic Education

Professor, Chair in Vision Sciences at Univ. of Aberdeen (UK); PhD in Optics and Visual Science, City Univ. (London, UK); Founder of Sight Science Ltd

Professor of Neurology at Harvard Medical School; Director of Research, Cognitive Neurology Unit, Beth Israel Deaconess Medical Center; MD/PhD Neurophysiology, Albert-Ludwigs Univ (Germany); Former Medical Fellow National Institute of Health; Author 450+ Scientific papers as well as several books

Professor of Neurology, Ophthalmology and Visual Sciences, University of British Columbia

Prof. Josef Zihl, Prof. emeritus in the Department of Psychology at University of Munich (Germany), and Head (retired) of the Neuropsychology Research Group at the Max Planck Institute of Psychiatry Munich

Chief of Stroke Division and Professor of Neurology at the University of Miami Miller School of Medicine