copyright © 2013 uni20years 20 years of...

“New ways for your products”

No. 1 Copyright © 2013 Uni20years PARIS, 2013 www.uni20years.comPrinted in France FREE

Issue 1Address: Unither Pharmaceuticals41 rue de la Chaussée d’Antin75009 PARIS / FranceTel.: +33 (0)1 44 63 51 70Fax: +33 (0)1 44 63 51 79

20 YEARS OF UNITHER

Unither Pharmaceuticals is 20 years old. Unither was created from a buyout of a Sanofi drug manufacturing plant, which at the time was generating turnover of $2.5 million, and it grew quickly in the sterile single-dose sector. In 2000, the management team formed a financial partnership to accelerate the Group’s development with a focus on external growth.

Unither then bought another sterile single-dose production site in 2002 and went on to diversify its portfolio by penetrating the effervescent segment and drug development with a buyout of the Créapharm Group in November 2005.

Over the last 20 years, Unither has been strengthening its position in drug manufacturing alongside its successful growth efforts by offering new solutions like the Unistick. We are keenly attuned to what our customers and the laboratories want while remaining true to our core mission of upholding the market position of existing brands by presenting the new product offering differently (galenics, packaging, etc.) and always innovating.

In addition to these innovations, Unither Pharmaceuticals is looking at the global landscape with a new subsidiary in Brazil and then in the U.S. in 2013 with the acquisition of UCB in New York state. The 250-person plant is an opportunity for us to become a global standard in our field and continue to produce UCB products. We plan to introduce our BFS and stick-pack technologies there so we can provide local manufacturing to our American customers. We are now setting our sights on other regions like China.

All of our staff and our partners deserve to be congratulated today for their dedication over the last two decades. We also want to thank our customers for their trust and say, “See you in 20 years in... 2033!”

See you soon,Eric Goupil, CEO

U N I 2 0 Y E A R S . C O M • U N I T H E R - P H A R M A . C O M

The Unither Pharmaceuticals 20th anniversary newsletter

For every type of consumption, product presentation has been focused on “portions” and “doses” for 20 years. There are many reasons for this.

Consumption awareness in the biscuit world opened a whole new avenue for products where now you could slip two or three biscuits into your child’s book bag pre-packaged in cellophane.

It’s the same at the office. Now you can just bring one portion of cheese and a mini-container of fruit salad. It’s convenient and more hygienic. No more waste, you always have the right amount.

So-called “mobile” consumption offers easily divisible parts and is more reliable. We no longer

open a whole bottle of Coca-Cola or Evian, just a can or small 33 cl bottle.

The same phenomena happened for detergent. Instead of pouring a dose of powder or liquid, manufacturers all over the world are successfully selling big tablets or liquid packets. They are easier to use, waste less product and are more convenient. It has been a standard for 20 years.

“Single-dose” products have been around for a long time. As early as 1919, Danone was marketing yoghurt in Spain that came in deposit jars and it was a key to their success.

In 1993, Unither began producing unidoses in Amiens as part of this trend. Today, Unither is one of the top trend-leaders and the global pioneer of the unidose.

For 20 years, Unither has been combining mobile use, convenience and hygiene. The venture began in Amiens in 1993. In 2013, Unither unidoses are being used in over 90 countries.

Eric Goupil, CEO of Unither Pharmaceuticals

Unither, the unidose leader

Unither turns 20

Unither PharmaceuticalsPARIS, FRANCE

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13 dates, 3 world regions

PAGE 2 • Uni20years • 2013

1993

1995

1997

2002

1994

1996

2005

20 yEArS of EvEntS

20 years of events at Unither and around the world


1993Unither is founded after a buyout of a plant in

Amiens. 17 employees.

Mandela receives the Nobel Peace Prize: South Africans Mandela and De Klerk are both awarded the Nobel Peace Prize for dismantling apartheid and restoring social equality. After spending 30 years in prison, Mandela is recognised for his fight for democracy. The following year, the famous political prisoner becomes president of South Africa.

Tritherapies are introduced to treat AIDS following the French-British clinical trial Concorde.

199450th anniversary of the Americans landing at

Normandy, France. On the eve of 6 June 1944, the Germans were astonished to see the Channel covered in war boats. The first wave of the Overlord Plan to take back Europe, Operation Neptune, had begun. The Americans land at Normandy to liberate France.

1995Unither focuses on sterile single doses, a

specialisation strategy for a solution that provides the right dose without preservatives.

The European currency, the euro, is introduced. On 1 January 1999, 11 national currencies disappear to give way for the single euro, the new common currency in Belgium, Germany, Spain, France, Ireland, Italy, Luxembourg, the

Netherlands, Austria, Portugal and Finland (Greece joins on 1 January 2001). The European

Central Bank is founded to manage Europe’s monetary policy.

The European Medicines Agency (EMA) is created.

1996The first mopral, omeprezole, proton pump

inhibitors go on the market to treat gastrointestinal ulcers.

1997Unither opens for exports in Europe and expands

its sales, operational and regulatory treatment capacities to international customers.

On 4 July 1997 – 28 years after the first moon walk – the man-made device Pathfinder drives on Mars. It brings along a variety of scientific instruments to study the atmosphere, climate and geology.

2002A new plant is acquired in Coutances and

Unither’s legacy technology BFS (Blow-Fill Seal) is consolidated.

The Concorde is grounded. The supersonic airliner designed by British Aerospace and Aérospatiale that flies at Mach 2 in altitudes over 16,000 m received its flight certificate in 1975. It is the most beautiful aircraft of all time, linking Paris to New York in three hours. It is equipped with a whole host of technological innovations in systems and materials.

Medicine travels great distances: In the wake of the world premier in September 2001 when a team of surgeons performed a gallbladder operation remotely between Strasbourg and New York, in November 2002 the same team conducts a 3D analysis of a patient’s medical record by consulting a number of specialists located several hundred kilometres away.

2005Acquisition of the Créapharm Group. The

acquisition brings new solutions, primarily effervescent technology and expertise in galenic and analytical development through its R&D centre in Bordeaux.

Brazilian footballer Ronaldinho playing for Chelsea is voted the best player of the year for the second time. He follows in the footsteps of Zinédine Zidane and his fellow countryman Ronaldo.

30 September: The Montreal Statement on the Human Right to Essential Medicines.

2006Unistick® is launched. Designed for liquid and

pasty forms, the stick-pack is a major advance for Unither’s capacity, first to offer unidose solutions and then to provide preservative-free unidoses.

The 250th anniversary of Mozart’s birth. Born in 1756, Mozart is the most famous musician in the world with 600 compositions that include symphonies, chamber music, works for piano and concerto, and opera. He has a formidable intellect from early childhood.

2006


2008

2009

2010

2013

2011


Composing was effortless for him; he often did not even correct his scores. He was able to blend Italian and German music, shifting from light-hearted to sombre.

For the first time, the H5N1 virus shows up in Europe with a dozen cases diagnosed in Turkey.

2008Boehringer Ingelheim closes its Bracknell plant

in England and hands all its production over to Unither.

J.M. Le Clézio wins the Nobel Prize in Literature in October 2008. The Prize is recognition for the French-Mauritian writer’s whole body of work. He lives in both Europe and South America. He is most known for his books Desert, The Prospector and The African. Time seems to stand still in his novels..

Matra Défense (EADS Group), Prof. Carpentier and his foundation, and Truffle Capital create CARMAT after developing a prototype of a fully optimised 900 gr artificial heart.

2009Takeover of Sanofi’s Colomiers site in France.

The rollout of liquid stick-pack technology meets demand of over 250 million sticks per year.

Michael Jackson dies in Los Angeles at age 50. Despite the controversies surrounding his private life and his death, The King of Pop is still the most popular singer of all time. The World Music Awards vote him Artist of the Millennium in 2000. We will always remember “Thriller” and “Bad”.

Nanorobot: Australian scientists develop a

nanorobot that is 250 micrometres in diameter (the thickness of two or three hairs) that can potentially control a brain.

2010Unither embarks on a series of projects to develop

a new sublingual medication solution. Uniflash® technology is one of the solutions tested.

The Shanghai World Expo. With the theme “Better City – Better Life” over 70 million people attend the event, making it the most visited expo in history. With 10 million visitors, the French Pavilion is the most popular, followed by the Chinese, Japanese and American pavilions.

2011Unither sales subsidiary opens in Brazil. The

Coutances site is granted FDA approval.

The 9/11 Memorial officially opens in the United States, 10 years after the terrorist attacks. The memorial features two square basins in the footprints of the two towers that were destroyed. They are fed by waterfalls cascading down the walls.

The European Parliament passes a European directive on counterfeit medicine: Directive 2011/62/EU. It requires all Member States in the EU to introduce a system by 2017 to protect their citizens against counterfeit medicine.

2013A plant is bought in Rochester, New York in

the United States. It allows Unither to deploy its unidose technologies (BFS and liquid stick), giving it a stronger foothold as a global leader in the sector.

The Colomiers site in France opens a pilot unit to develop preservative-free liquid sticks.

When it comes to ambition, Google doesn’t stop halfway. On Wednesday, 18 September, the American Internet giant posts a letter on its site announcing the creation of Calico. The company’s self-appointed mission is to “[focus] on health and well-being, in particular the challenge of aging and associated diseases.”

In other words, by taking on aging the IT giant’s budding subsidiary is embarking on a quest to cure mortality.

Watch videos of eventsto celebrate

Unither’s 20th anniversary on its special event website!

uni20years.com

QuizSpoofs


Flashbacks 10 questions about UnitherAnswers provided at the end of the quiz

1: What is Unither’s legacy technology?□ A. BFS□ B. ERG□ C. ECH

2: How many industrial sites does Unither have around the world?□ A. 3□ B. 5□ C. 6

3: Low-humidity rooms are especially useful for manufacturing ...□ A. sterile unidoses□ B. effervescent tablets□ C. powder Unistick

4: Where is the Unither Group’s research and development division located?□ A. Bordeaux, France□ B. Rochester, U.S.□ C. Sao Paulo, Brazil

5: What is the most common use for BFS technology?□ A. Anodynes□ B. Wound cleansing□ C. Asthma

6: In 2013, what is the Unither Group’s production capacity for sterile unidoses?□ A. 500,000,000□ B. 1 000,000,000□ C. 2 000,000,000

7: What was the Unither Group’s turnover in 2012?□ A. Over $50 million□ B. Over $100 million□ C. Over $200 million

8: In what year did Unither begin operations to Brazil?□ A. 1998□ B. 2010□ C. 2011

9: Unither started after buying out a plant from which company?□ A. Sanofi□ B. Unilever□ C. WalMart

10: What does the star in Unither’s logo symbolise?□ A. The company’s human dimension□ B. Innovation□ C. Excellence


Answers1. BFS (Blow-Fill Seal), 2. 6 (Amiens, Coutances, Gannat, Bordeaux, and Colomiers in France; Rochester in the U.S.), 3. Effervescent tablets, 4. Bordeaux, France, 5. Asthma, although ophthalmologic is growing sharply, 6. 2,000,000,000, 7. $216 million, 8. 2013, 9. Sanofi, 10. All three!

1989 - The fall of the Berlin Wall

2013 - Unither Pharmaceuticals created the characters TIK the Unistick® and DOZ the Unidose

See the original photos on the newsletter’s online version

Photo :Yann Forget

2009 - All the living US presidents

Photo :Y Joyce N. Boghosian

2012 - Curiosity on Mars

Photo : NASAIf you answered more than 5 of the 10 questions correctly, you really know Unither!

Visit the special 20th anniversary website: uni20years.com

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