coordinated bacterial behaviour
DESCRIPTION
Coordinated bacterial behaviour. Skin diseases. Wound infection. Biofilm formation. Swarming motility. Quorum Sensing = Intercellular Signaling. Bioluminescence. Fruit body formation. Yoghurt production. Symbiosis. Pathogenicity. AHLs. Sin quorum sensing: - PowerPoint PPT PresentationTRANSCRIPT
Coordinated bacterial behaviour
Swarming motilityBiofilm formation
Symbiosis Pathogenicity
Fruit bodyformation
Bioluminescence
Quorum Sensing= Intercellular Signaling
Wound infection Skin diseases
Yoghurt production
after 3 d on agar
activation
Sin quorum sensing: a system of transcription control
WT
sinI-
expR-
sinR-
QS behaviour
SinISinR
AHLs
AHLs
AHLs
AHLs
nutrient limitation
ExpRAHLs
AHLs
A more detaileddescription
SinISinR
ExpR
resting state
SinISinR
AHLs
ExpR
nutrient limitation
positive feedback
negative feedback
SinISinR
AHLs
AHLsExpR
SinR
AHLs
ExpRAHLs
expression of green fluorescent protein fromthe sinI promoter
0 10 20 300
5000
10000
15000
20000
sinI promoter-egfp fusion
time (hours)
F/c
ell
log growth intermediate growth stat. phase
resting state nutrient limitation activation positive feeback negative feedback
AHL concentration 0-5 nM 5-20 nM 20-1000 nMin growth medium:
SinISinR
ExpR
SinISinR
AHLs
ExpR
nutrient limitation
SinISinR
AHLs
AHLsExpR
SinR
AHLs
ExpRAHLs
intermediate stagelog growthlog growthstat. phase & lag phase