controls of the cell cycle
DESCRIPTION
Controls of the Cell Cycle. External Chemical Physical. Internal. Ex. At M phase checkpoint. Chemical signals essential nutrient growth factors. Density-dependent inhibition crowded cells stop dividing. Cells must be attached to a substratum - PowerPoint PPT PresentationTRANSCRIPT
Controls of the Cell Cycle
Internal ExternalExternalChemical Chemical PhysicalPhysical
Ex. At M phase checkpoint
Chemical signals
essential nutrientgrowth factors
1. Density-dependent inhibition
• crowded cells stop dividing
Cells must be attached to a substratum
ex. inside of a culture jar or ECMof a tissue
Don’t respond to body’s control mechanisms
Divide excessively
Don’t exhibit density-dependent inhibition
“Immortal”
HeLa cells
Diverse
Gene alteration
Worst 5 Foods
www.copperwiki.org/index.
HOW CANCER CELLS HOW CANCER CELLS SPREADSPREAD
Transformation (normal cell to cancer cell)
Tumor (mass of abnormal cells w/in normal tissue)
Benign tumor
Malignant tumor / cancer
Metastasis
How
Cancer
Cells
Spread
1. High-energy radiation
For localized tumor
Destroys DNA in cancer cells
2.Chemotherapy
For metastatic tumors
For actively dividing cells
Side effects
To summarize…To summarize…