ConTenTs

DEAN’S ORATION

Polypill: Can it stall CVD? .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. xxvii BB Thakur

SEcTION 1cardiovascular Disease: An Update

Chapter 1 Aortic Aneurysms: Is Thoracoabdominal Aorta Dispensable? .. .. .. .. .. .. .. .. 3 Devi Shetty

Chapter 2 Endovascular Therapy: Lessons Learnt and Way Forward. .. .. .. .. .. .. .. .. .. .. 5 Sanjay Tyagi, Amit Mittal

Chapter 3 Rheumatic Heart Disease: The Indian Scenario .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. 20 Surendra Nath Khanna

Chapter 4 Aortic Stenosis: Changing Trends of Indication and Treatment .. .. .. .. .. .. 27 Ashok Seth, Vijay Kumar

Chapter 5 Ad Hoc Coronary Angioplasty: Current Consensus .. .. .. .. .. .. .. .. .. .. .. .. .. 43 BK Goyal, Shalima Gautam

Chapter 6 No Option Coronary Artery Disease: What are the Options? .. .. .. .. .. .. .. .. 48 Nakul Sinha

SEcTION 2cardiology: New Vistas

Chapter 7 Chirally Pure Medicine: Therapeutic Advances . .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. 59 YP Munjal, Kamlesh Tewary

Chapter 8 Management of Resistant Hypertension . .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. 66 KK Talwar, Sandeep Banga, A Bhardwaj

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Chapter 9 Diastolic Heart Failure: Diagnosis and Management .. .. .. .. .. .. .. .. .. .. .. .. 73 Murlidhar S Rao

Chapter 10 Refractory Ventricular Tachycardia: Approach to Management .. .. .. .. .. .. 86 Amit Vora, Kavita Tyagi

SEcTION 3Endocrinology: contemporary Issues

Chapter 11 Primary Aldosteronism: A Clinical Update .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. 97 Ashok Kumar Das, Susanth MJ

Chapter 12 Transient Thyroiditis: A Physician’s Dilemma. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 117 KJ Shetty, KN Manohar, KV Sravan Kumar

Chapter 13 Pituitary Tumors: An Approach to Diagnosis and Management .. .. .. .. .. . 127 Nihal Thomas, Nitin Kapoor

Chapter 14 Polyglandular Insufficiency: Management Approach .. .. .. .. .. .. .. .. .. .. .. . 137 Arpandev Bhattacharyya, Swaraj Waddankeri

Chapter 15 Male Infertility: How to Tackle the Problem? .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 146 Subhankar Chowdhury, Soumik Goswami

Chapter 16 Hormone Replacement Therapy and Bisphosphonates: Is there a Consensus? .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 157

Lily John, Nitin K Srivastava

SEcTION 4Diabetes/Metabolic Disorders: current Perspectives

Chapter 17 Metabolic Memory: Its Vascular Implications. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 165 Siddharth N Shah

Chapter 18 Oral Hypoglycemic Agents in Gestational Diabetes Mellitus: Past, Present and Future .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 172

VN Mishra, Nalini Mishra

Chapter 19 Incretin Based Therapy: Current Concepts .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 179 Apurba Kumar Mukherjee, Sandip Ghosh

Chapter 20 Controversy and Pitfalls of Prandial Glucose Management . .. .. .. .. .. .. .. . 193 Anil K Mandal, Linda M Hiebert, Harry Khamis

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Chapter 21 Hypoglycemia in Diabetes: Contentious Issues. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 202 Ajay Kumar

Chapter 22 Dyslipidemia: New Facets and Current Controversies . .. .. .. .. .. .. .. .. .. .. . 211 PC Manoria, Pankaj Manoria, Piyush Manoria, SK Parashar

SEcTION 5Futuristic Medicine: Moving Forward

Chapter 23 Robotics in Medicine . .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 227 RD Lele

Chapter 24 Regenerative Medicine: An Overview with Special Reference to Stroke .. .. . 241 Kameshwar Prasad, Meenakshi N, Paresh Zanzmera

Chapter 25 Emerging Role of Biologics in Clinical Medicine: An Overview. .. .. .. .. .. . 257 Sita Naik

SEcTION 6Diagnostic Medicine: State-of-the-Art

Chapter 26 Bedside and Hand-Held Ultrasound:An Emerging Tool in Rapid Diagnosis . .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 267

SK Sharma

SEcTION 7Gastrohepatology: Recent Advances

Chapter 27 Chronic Pancreatitis: Newer Insights into Pathophysiology and Treatment. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 277 D Nageshwar Reddy, Rupjyoti Talukdar

Chapter 28 Non-ulcer Dyspepsia: Clinical Approach .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 287 Gourdas Choudhuri, Vikas Sengar

Chapter 29 Gastroesophageal Reflux Disease: Work-up and Management . .. .. .. .. .. . 294 Showkat Ali Zargar

Chapter 30 Irritable Bowel Syndrome: Challenges in Diagnosis and Treatment . .. .. . 305 Rajendra Kumar Jain

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Chapter 31 Acute Liver Failure: Indian Perspective .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 315 Anil Arora, Praveen Sharma

SEcTION 8Neurology Update

Chapter 32 Alzheimer’s Disease: New Perspectives in Treatment .. .. .. .. .. .. .. .. .. .. .. . 323 PM Dalal, M Bhattacharjee

Chapter 33 Epilepsy: How to Avoid Misdiagnosis and Mismanagement? . .. .. .. .. .. .. . 330 Manjari Tripathi, Abhishek

Chapter 34 Myalgic Encephalopathy or Chronic Fatigue Syndrome . .. .. .. .. .. .. .. .. .. . 342 Joy Desai

Chapter 35 Parkinson’s Disease Management: Newer Perspectives . .. .. .. .. .. .. .. .. .. . 346 Pramod K Pal, Ketaki Ravindra Jhavar

Chapter 36 Transient Loss of Consciousness: Management Principles .. .. .. .. .. .. .. .. . 357 Mrinal Kanti Roy, Dhiman Das

SEcTION 9Rheumatology: Future Insights

Chapter 37 Pre-clinical Rheumatoid Arthritis: Back to the Future .. .. .. .. .. .. .. .. .. .. .. . 369 G Narsimulu, Ramakrishna Naidu

Chapter 38 Systemic Sclerosis: The Changing Therapeutic Landscape .. .. .. .. .. .. .. .. . 374 Ghan Shyam Pangtey, Sanjay Parmar

Chapter 39 SLE Management: Moving Forward in Diagnosis and Treatment .. .. .. .. . 391 Satyabrata Ganguly, Rajan Palui

Chapter 40 Vitamin D: Current Treatment Guidelines .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 400 CV Harinarayan

SEcTION 10Renal Medicine: current concept

Chapter 41 An Approach to Podocytopathies . .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 409 Narinder Pal Singh, Ankit Jain, Taposh Sarkar

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Chapter 42 Diagnosis and Management of Membranous Glomerulonephritis in 2012 .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 417 Vivekanand Jha

Chapter 43 Acute Kidney Injury: Current Management.. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 424 SC Dash

Chapter 44 Chronic Kidney Disease and Anemia .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 435 Kamlakar Tripathi, Sunny Garg, Lalit P Meena, Mousumi Kundu

Chapter 45 Protect Your Kidneys: Save Your Heart . .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 444 Sree Bhushan Raju

Chapter 46 Recurrent Urinary Tract Infections . .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 452 SNA Rizvi, Yasir Rizvi

SEcTION 11Respiratory Medicine Update

Chapter 47 Solitary Pulmonary Nodule: Approach to Diagnosis . .. .. .. .. .. .. .. .. .. .. .. . 467 Alladi Mohan, B Vijayalakshmi Devi, D Prabath Kumar, J Hari Krishna

Chapter 48 Approach to Interstitial Lung Disease: Diagnosis and Treatment .. .. .. .. . 480 JD Sunavala

Chapter 49 Chronic Obstructive Pulmonary Disease Management: Newer Perspectives . .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 491 PS Shankar

Chapter 50 Obstructive Sleep Apnea Syndrome: Management Perspectives . .. .. .. .. . 497 VK Vijayan

Chapter 51 Unexplained Cough: Management Approach. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 505 Debajyoti Bhattacharyya, Madhu Sudhan Barthwal

Chapter 52 Casual versus Comorbid Relationship between Obstructive Sleep Apnea and Metabolic Syndrome .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 512

SN Arya

SEcTION 12Infectious Diseases: current Aspects

Chapter 53 Salmonella Infections and Epidemics: Reservoirs and Resistance . .. .. .. . 523 RK Singal, Atul Bhasin

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Chapter 54 Diarrhea .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 528 Pranesh Nigam, KK Dwivedi, Praveen Kumar, Rajendra Chaudhary

Chapter 55 Cardiovascular Manifestations of HIV Infection/AIDS .. .. .. .. .. .. .. .. .. .. . 537 S Bhagyabati Devi, Th Sachin Deba Singh, Robinson Ningshen

Chapter 56 Malarial Hepatopathy .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 551 AP Mohanty

Chapter 57 Parasites that Still Challenge: Indian Perspectives .. .. .. .. .. .. .. .. .. .. .. .. .. .. 561 Bibhuti Saha, Shishir Kumar

Chapter 58 XDR-Tuberculosis: Management Principle .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 573 KK Lohani

Chapter 59 Is There Hope for Malaria Vaccine: What the Pandit Says? .. .. .. .. .. .. .. .. . 580 PC Bhattacharyya, Manabendra Nayak

SEcTION 13Hematology/Oncology: Recent Advances

Chapter 60 Approach to Thrombocytopenia .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 591 Farah Jijina, Mallikarjun Kalashetty

Chapter 61 Adult Acute Lymphoblastic Leukemia: Management Issues .. .. .. .. .. .. .. . 601 Ashish Dixit

Chapter 62 Aplastic Anemia: Current Management Issues .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. . 608 Manoranjan Mahapatra, Avinash Singh

Chapter 63 Megaloblastic Anemia in Tropics: The Emerging Trends .. .. .. .. .. .. .. .. .. . 616 Jina Bhattacharyya, Sangitanjan Dutta

Chapter 64 Human Papillomavirus, Cervical Cancer Vaccine and Male Cancers .. .. . 624 Purvish M Parikh Index .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. 631