contents · 2018. 5. 16. · assalamualaikum w.b.t. and salam sejahtera. on behalf of the...

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7 TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM) IN CONJUNCTION WITH 3 RD NATIONAL CONFERENCE FOR CANCER RESEARCH (NCRR) MALAYSIA Message from the Science Advisor for the Prime Minister of Malaysia ............... 2 Message from Vice-Chancellor of Universi Kebangsaan Malaysia ..................... 3 Message from Chairman of the Organising Commiee ....................................... 4 Opening Ceremony ............................................................................................. 5 Scienfic Programme.......................................................................................... 6 Faculty of Speakers ........................................................................................... 11 Young Invesgator Award ................................................................................. 12 Free Papers Presentaons ................................................................................ 14 Lab Visitaon & Meet the Expert Sessions ........................................................ 15 Conference Informaon.................................................................................... 16 Emergency Evacuaon Plan .............................................................................. 17 Layout and Directory of the Exhibitors .............................................................. 18 Organising Commiee ...................................................................................... 19 Acknowledgement ........................................................................................... 20 Contents 1

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  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Message from the Science Advisor for the Prime Minister of Malaysia ...............2

    Message from Vice-Chancellor of Universiti Kebangsaan Malaysia .....................3

    Message from Chairman of the Organising Committee .......................................4

    Opening Ceremony .............................................................................................5

    Scientific Programme ..........................................................................................6

    Faculty of Speakers ...........................................................................................11

    Young Investigator Award .................................................................................12

    Free Papers Presentations ................................................................................14

    Lab Visitation & Meet the Expert Sessions ........................................................15

    Conference Information....................................................................................16

    Emergency Evacuation Plan ..............................................................................17

    Layout and Directory of the Exhibitors ..............................................................18

    Organising Committee ......................................................................................19

    Acknowledgement ...........................................................................................20

    Contents

    1

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Message from the Science Advisor for the Prime Minister of Malaysia

    Assalamualaikum w.b.t. and Salam Sejahtera.

    A very warm welcome to all participants and speakers to the 7th Regional Conference on Molecular Medicine in conjunction with 3rd National Congress for Cancer Research. I feel very honoured to be invited to write this message for the programme book. As a researcher myself, I value the tradition of a scientific conference which brings together researchers, academics, professionals, students and industry players from various countries to share and discuss their findings and expertise. The challenge nowadays in research is how to effectively harness the transformative power of scientific findings to make life-changing initiatives and game-changing innovations that will benefit the people and communities. For this purpose, the sharing expertise and discussions between the leading experts and our local researchers will certainly help strengthen research collaboration. The participation of the post-graduate students and young scientists will also enhance the scientific talent pool in the nation. For the medical and health sector, molecular medicine or precision medicine is already making significant inroads in healthcare and providing personalised therapies to patients with various diseases including cancer.

    I am proud that this outstanding conference is organised by UKM Medical Molecular Biology Institute (UMBI), which is one of the leading institutes in cancer and molecular medicine research in Malaysia. I am impressed with the line-up of invited speakers, both local and international experts for that I believe, they will deliver an impetus to stimulate new and exciting ideas in research and collaboration. I would like to thank the speakers for their participations and the organising committee for arranging an impressive scientific programme. I encourage the young academics and postgraduate students to engage and interact with the experts to gain wisdom and valuable advice and ideas for their future research.

    Lastly, I want to thank the Universiti Kebangsaan Malaysia (UKM) and UMBI for taking the initiative to host the event as well as the sponsors for taking the opportunity to engage in research and scientific collaboration. My best wishes for an engaging and memorable conference.

    Professor Tan Sri Dr. Zakri Abdul HamidScience Advisor for the Prime Minister of Malaysia

    2

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Message from Vice-Chancellor of Universiti Kebangsaan

    Malaysia

    Assalamualaikum w.b.t. and Salam Sejahtera.

    I am delighted to welcome all the speakers and participants to the 7th Regional Conference on Molecular Medicine in conjunction with 3rd National Congress for Cancer Research. The twin elements of this conference will cover a wide range of hot topics in the fields of cancer and lifestyle-related chronic diseases. I am proud that UMBI is again taking the lead in organising a national-level conference focused on molecular medicine and cancer. As a Higher Institution Centre of Excellence under the Ministry of Higher Education, this leadership role certainly reflects the strength of UMBI in cancer and molecular medicine research. UMBI is one of the flagship research institutes of UKM which has make a national impact with projects such as The Malaysian Cohort and the Space Science Programme.

    I would like to congratulate the organising committee and the management of UMBI for their efforts in organising this conference. Special thanks to the scientific committee for coming up with an outstanding programme packed with lectures on the latest findings and developments as well as cutting edge technologies. These lectures will certainly stimulate new research interests and collaboration. I would also like to thank the invited speakers, for sharing their insights and exciting findings with us. The poster discussion and oral presentation sessions will certainly provide a good opportunity for our local researchers particularly the young scientists to share their research findings.

    I hope this conference will be a pleasant and fruitful event to the participants, both socially and scientifically. I also encouraged the interaction of research students and young academics with the more established experts, to exchange views and wisdoms. This conference will certainly provide a networking opportunity for the researchers to form new collaboration in research. Lastly, to the international speakers and delegates, I hope you will enjoy the warmth and friendliness our Malaysian hospitality as well as our cultural and architectural delights.

    Professor Tan Sri Dato’ Seri Dr. Noor Azlan GhazaliVice-Chancellor

    Universiti Kebangsaan Malaysia (UKM)

    3

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Message from Chairman of the Organising

    Committee

    Assalamualaikum w.b.t. and Salam Sejahtera.

    On behalf of the organising committee, it gives me a great pleasure to extend a warm welcome to all the speakers and participants to the 7th Regional Conference on Molecular Medicine in conjunction with 3rd National Conference for Cancer Research. Molecular or genomics medicine has paved the way for precision medicine which is tailoring the treatment based on the individual genes, lifestyle and environment. Precision medicine is already changing healthcare practices and the research in molecular medicine will certainly discover new knowledge and more biomarkers that could be applied to the management of patients. This year, we have an impressive faculty of speakers, local and international, who will be sharing with us their knowledge and research findings. Our international speakers come from as far as Australia and also from Singapore and Thailand. I am pleased to say that the scientific committee has prepared an exciting programme over 3 days covering plenary talks and symposia, which should provide the latest updates in the field molecular medicine and cancer research. Importantly, this conference would not be possible without the excellent papers contributed by participants. I thank all the participants for their contributions and their partaking in the poster and oral presentations.

    I would like to thank the top management of UKM for the support and to all our sponsors. I hope that this smart partnership with the industry will continue in future. I also thank all the members of the scientific and organising committee from UMBI for the excellent works. Lastly, I wish everyone a successful conference and fruitful sharing of knowledge.

    Professor Datuk Dr. A Rahman A JamalChairman of the Organising Committe

    7th Regional Conference on Molecular Medicine (RCMM)

    in conjunction with 3rd National Conference for Cancer Research (NCRR)

    &

    Director

    UKM Medical Molecular Biology Institute (UMBI)

    Universiti Kebangsaan Malaysia (UKM)

    4

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Opening Ceremony

    7th Regional Conference on Molecular Medicine (RCMM) in conjunction with 3rd National Conference for Cancer Research (NCRR)

    10th NOVEMBER 2017, FRIDAY

    Venue

    Auditorium, Ground Floor & Level 1UKM Medical Molecular Biology Institute (UMBI)

    0930

    0935

    0940

    0950

    1015

    -Seating of Conference Delegates & Guests

    -Arrival of Vice-Chancellor, Universiti Kebangsaan Malaysia Professor Tan Sri Dato’ Seri Dr. Noor Azlan Ghazali

    -Arrival of Guest of Honour Professor Tan Sri Dr. Zakri Abdul Hamid Science Advisor for the Prime Minister of Malaysia

    -Negaraku

    -Doa Recital

    -Multimedia Presentation

    -Welcome Speech by Chairman of the Organising Committee Professor Datuk Dr. A Rahman A Jamal

    -Speech by Vice-Chancellor, Universiti Kebangsaan Malaysia Professor Tan Sri Dato’ Seri Dr. Noor Azlan Ghazali

    -Speech and Official Opening of the “7th Regional Conference on Molecular Medicine (RCMM) in conjunction with 3rd National Conference for Cancer Research (NCRR)” by Professor Tan Sri Dr. Zakri Abdul Hamid Science Advisor for the Prime Minister of Malaysia

    -Tea Break

    5

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Scientific Programme

    DAY 1 – FRIDAY 10 NOVEMBER 2017

    0800 - 0900 Registration of participants

    0900 - 0945PLENARY 1 Precision MedicineLaureate Professor Dr. Rodney John Scott (University of Newcastle, Australia)

    Chairperson: Professor Datuk Dr. A Rahman A Jamal (UKM, Malaysia)Venue: Auditorium, Level G & 1

    0945 - 1015 Opening CeremonyVenue: Auditorium, Level G & 1

    1015 - 1045 Tea Break, Booth & Poster Viewing

    1045 - 1215

    SYMPOSIUM 1 Cancer GeneticsChairperson: Dr. Nurul Syakima AB Mutalib (UKM, Malaysia)

    Venue: Auditorium, Level G & 1

    i. Panel Testing for Breast Cancer: How Valuable Is It? Laureate Professor Dr. Rodney John Scott (University of Newcastle, Australia)

    ii. Genetic Predisposition to Breast Cancer in Asian Women Professor Dr. Teo Soo Hwang (Cancer Research Malaysia, Malaysia)

    iii. Precision Medicine in Colorectal Cancer: A Local Experience Professor Datuk Dr. A Rahman A Jamal (UKM, Malaysia)

    SYMPOSIUM 2 Non-Communicable Diseases and Preventive MedicineChairperson: Professor Dr. Shamsul Azhar Shah (UKM, Malaysia)

    Venue: Seminar Lounge, Level 8

    i. Genotype and Phenotype Determinants Among Malaysian Malays with HypercholesterolemiaDr. Nor Azian Abdul Murad (UKM, Malaysia)

    ii. Epigenetics in Chronic Obstructive Pulmonary Disease (COPD): A Moving TargetAssociate Professor Dr. Tidi Maharani Hassan (UKM, Malaysia)

    iii. Vitamin D and Diabetes Risk: Current Evidences and ChallengesAssociate Professor Dr. Foo Leng Huat (USM, Malaysia)

    1215 - 1430 Lunch (Venue: Level G) & Friday Prayers

    6

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    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    1300 - 1400 Lab VisitationPlease refer to page 15 for more information

    1430 - 1615

    SYMPOSIUM 3 Molecular Diagnostics and Targeting in Cancer Chairperson: Dr. Tan Shing Cheng (UKM, Malaysia)Venue: Auditorium, Level G & 1

    i. Next Generation Sequencing in Translational Cancer Research, Delivering Value and UtilityMr. Kahlil Lawless (Illumina Inc./Science Vision Sdn Bhd)

    ii. Is There a Role for NGS in Diagnostic Oncology?Dr. Subramanian Yegappan (Hospital Ampang, Malaysia)

    iii. Models for Translational Research in Nasopharyngeal CarcinomaDr. Alan Khoo Soo Beng (Institute for Medical Research (IMR), Malaysia)

    SYMPOSIUM 4 Proteomics and Metabolomics in Today’s EraChairperson: Dr. Chin Siok Fong (UKM, Malaysia)Venue: Seminar Lounge, Level 8

    i. Reconciling Proteomics with Next Generation SequencingAssociate Professor Dr. Low Teck Yew (UKM, Malaysia)

    ii. Metabolomics and Integrated Biology: Increasing Biological UnderstandingDr. Robin Philp (Agilent Technologies)

    iii. Secretomics: The Challenges and StrategiesAssociate Professor Dr. Saiful Anuar Karsani (UM, Malaysia)

    1615 - 1645 Tea, Poster Viewing & Judging

    1645 - 1730 PLENARY 2

    Applications of Nanotechnology in Cancer Management – From Diagnostics to Therapeutics

    Professor Dr. Jackie Yi-Ru Ying (A* Star, Singapore)Chairperson: Professor Datuk Dr. A Rahman A Jamal (UKM, Malaysia)

    Venue: Auditorium, Level G & 1

    7

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    DAY 2 – SATURDAY 11 NOVEMBER 2017

    0800 - 0900

    YOUNG INVESTIGATOR AWARD 1Non Cancer (6 abstracts)

    Chairperson: Dr. Nor Adzimah Johdi (UKM, Malaysia)Venue: Seminar Lounge, Level 8

    Please refer to page 12 and 13 for more information

    YOUNG INVESTIGATOR AWARD 2Cancer (6 abstracts)

    Chairperson: Dr. Chin Siok Fong (UKM, Malaysia)Venue: Auditorium, Level G & 1

    Please refer to page 12 and 13 for more information

    0900 - 1030

    SYMPOSIUM 5Microbiome in Health and Disease

    Chairperson: Associate Professor Dr. Tidi Maharani Hassan (UKM, Malaysia)Venue: Auditorium, Level G & 1

    i. Debugging Lung Disease: Applying Precision Medicine and Metagenomics to the Pulmonary MicrobiomeDr. Sanjay Chotirmall (Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore)

    ii. The Facial Skin Microbiota and Their Correlation with HealthAssistant Professor Dr. Naraporn Somboonna (Chulalongkorn University, Thailand)

    iii. Microbiome in CRC: Our Local ExperienceAssociate Professor Dr. Neoh Hui-min (UKM, Malaysia)

    SYMPOSIUM 6Cancer Immunology & Immunotherapy

    Chairperson: Dr. Nor Adzimah Johdi (UKM, Malaysia)Venue: Seminar Lounge, Level 8

    i. Are Macrophages in the Tumour Microenvironment Useful Targets for Develop-ment of Cancer Therapeutics?Professor Dr. Seow Heng Fong (UPM, Malaysia)

    ii. Opportunities for Cancer Immunotherapy in Head and Neck CancerDr. Lim Kue Peng (Cancer Research Malaysia, Malaysia)

    iii. Development and Application of Full-Length, Correctly Folded Human Protein Mi-croarrays: Drug Selectivity Screening and Diagnostic Biomarker DiscoveryDr. Dayangku Haslina Pangiran Razali (Sengenics Sdn Bhd)

    1030 - 1100 Tea Break

    1100 - 1145 PLENARY 3

    The Application of Next Generation Sequencing in Rare Diseases Associate Professor Dr. Roger Foo

    (Cardiovascular Research Institute, National University of Singapore, Singapore)

    Chairperson: Professor Datuk Dr. A Rahman A Jamal (UKM, Malaysia)Venue: Auditorium, Level G & 1

    8

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    1145 - 1230 PLENARY 4

    Biobanking for the Future Professor Datuk Dr. A Rahman A Jamal (UKM, Malaysia)

    Chairperson: Dr. Nurul Syakima Ab MutalibVenue: Auditorium, Level G & 1

    1230 - 1400 Lunch (Venue: Level G) & Break

    1400 - 1530

    SYMPOSIUM 7Bioinformatics & Clinical Applications

    Chairperson: Associate Professor Dr. Low Teck Yew (UKM, Malaysia)Venue: Auditorium, Level G & 1

    i. Computational 3D Protein Side-Chain Comparisons: Applications in Drug Repurposing and Toxicity ScreeningAssociate Professor Dr. Mohd Firdaus Mohd Raih (UKM, Malaysia)

    ii. Improving Driver Prediction for Precision Oncology using a Consensus ApproachDr. Niranjan Nagarajan (Genome Institute of Singapore (GIS), Singapore)

    iii. Genetics of Sudden Cardiac DeathAssociate Professor Dr. Roger Foo (Cardiovascular Research Institute, National University of Singapore, Singapore)

    SYMPOSIUM 8State of the Art Technologies

    Chairperson: Dr. Ezanee Azlina Mohamad Hanif (UKM, Malaysia)Venue: Seminar Lounge, Level 8

    i. Automation as a Best Practice in Cryogenic Storage and Handling of Biological SamplesMr. Jason Huang (FC Bios Sdn Bhd)

    ii. Novaseq - The Next Era Sequencing TechnologyDr. Liu Fang Fang (Illumina Inc./Science Vision Sdn Bhd)

    iii. Overcoming Common NGS Challenges- From Research to DiagnosticsDr. Chiam Chun Wei (Qiagen Biotechnology Malaysia Sdn Bhd)

    1530 - 1600 Tea Break & Poster Judging

    1600 - 1800

    Free Papers: Non Cancer & CancerChairperson: Dr. Lee Pey Yee (UKM, Malaysia)

    Venue: Auditorium, Level G & 1Please refer to page 14 for more information

    2000 - 2200 Faculty Dinner (For Speakers)

    9

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    DAY 3 – SUNDAY 12 NOVEMBER 2017

    0730 - 0830Meet the expert session and Hot Breakfast

    (Limited to 10 participants per expert)Venue: Meeting Room Level 5, 7 & 9

    0830 - 1000

    INDUSTRY SYMPOSIUM

    Advances in Molecular DiagnosticsChairperson: Dr. Siti Aishah Sulaiman (UKM, Malaysia)

    Venue: Auditorium, Level G & 1

    i. Nanostring TechnologiesDr. Caroline Chan (Nanostring (USA), sponsored by Genomax Technologies Pte Ltd)

    ii. Digital Droplet PCR Technology and Single Cell ResearchAssociate Professor Dr. Richie Soong (sponsored by Bio-Rad Laboratories & Biomarketing Sdn Bhd)

    iii. Next Generation Sequencing and Precision Medicine Dr. Edward Wong (Axil Scientific Pte Ltd, sponsored by First BASE Laboratories Sdn Bhd)

    SYMPOSIUM 10Point of Care Testing (PoCT) for Infectious Diseases

    Chairperson: Associate Professor Dr. Neoh Hui-min (UKM, Malaysia)Venue: Seminar Lounge, Level 8

    i. Lateral Flow Rapid Tests for Neglected Parasitic DiseasesProfessor Dr. Rahmah Noordin (INFORMM, Malaysia)

    ii. PoCT for Common Malaysian Bacterial DiseasesDr. Fairuz Amran (Institute for Medical Research (IMR), Malaysia)

    iii. Chlamydia Trachomatis Detection Using the LAMP MethodAssistant Professor Dr. Naraporn Somboonna (Chulalongkorn University, Thailand)

    1000 - 1030 Tea Break

    1030 - 1115 PLENARY 5

    Integrated Epigenomic and Genomic Profiling in Asian Cancers Professor Dr. Teh Bin Tean

    (National of Singapore (NUS), Singapore)Chairperson: Professor Datuk Dr. A Rahman A Jamal (UKM, Malaysia)

    Venue: Auditorium, Level G & 1

    1115 - 1300Closing Ceremony (Venue: Auditorium, Level G & 1) &

    Lunch (Venue: Level G)

    10

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Faculty of Speakers

    NO. SPEAKERS DEPARTMENT/UNIVERSITY/COMPANY

    1 Laureate Professor Dr. Rodney John Scott University of Newcastle, Australia

    2 Professor Datuk Dr. A Rahman A Jamal National University of Malaysia, Malaysia

    3 Professor Dr. Jackie Yi-Ru Ying A* Star, Singapore

    4 Professor Dr. Rahmah Noordin INFORMM, University of Science Malaysia, Malaysia

    5 Professor Dr. Seow Heng Fong Universiti Putra Malaysia, Malaysia

    6 Professor Dr. Teh Bin Tean National University of Singapore, Singapore

    7 Professor Dr. Teo Soo Hwang Cancer Research Malaysia, Malaysia

    8 Associate Professor Dr. Foo Leng Huat University of Science Malaysia, Malaysia

    9 Associate Professor Dr. Low Teck Yew National University of Malaysia, Malaysia

    10 Associate Professor Dr. Mohd Firdaus Mohd Raih National University of Malaysia, Malaysia

    11 Associate Professor Dr. Neoh Hui-min National University of Malaysia, Malaysia

    12 Associate Professor Dr. Roger Foo National University of Singapore, Singapore

    13 Associate Professor Dr. Saiful Anuar Karsani University of Malaya, Malaysia

    14 Associate Professor Dr. Tidi Maharani Hassan National University of Malaysia, Malaysia

    15 Assistant Professor Dr. Naraporn Somboonna Chulalongkorn University, Thailand

    16 Dr. Alan Khoo Soo Beng Institute for Medical Research, Malaysia

    17 Dr. Fairuz Amran Institute for Medical Research, Malaysia

    18 Dr. Lim Kue Peng Cancer Research Malaysia, Malaysia

    19 Dr. Niranjan Nagarajan Genome Institute of Singapore, Singapore

    20 Dr. Nor Azian Abdul Murad National University of Malaysia, Malaysia

    21 Dr. Sanjay Chotirmall Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore

    22 Dr. Subramanian Yegappan Hospital Ampang, Malaysia

    23 Associate Professor Dr. Richie SoongCancer Science Institute, National University Singapore, Singapore; Bio-Rad Laboratories & Biomarketing Sdn Bhd

    24 Dr. Caroline Chan Nanostring (USA) / Genomax Technologies Pte Ltd

    25 Dr. Chiam Chun Wei Qiagen Biotechnology Malaysia Sdn. Bhd

    26 Dr. Dayangku Haslina Pangiran Razali Sengenics Sdn Bhd

    27 Dr. Edward Wong Axil Scientific Pte Ltd, First BASE Laboratories Sdn Bhd

    28 Dr. Liu Fang Fang Illumina Inc., ScienceVision Sdn Bhd

    29 Dr. Robin Philp Agilent Technologies

    30 Mr. Kahlil Lawless Illumina Inc., Science Vision Sdn Bhd

    31 Mr. Jason Huang FC Bios Sdn Bhd

    11

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Young Investigator Award

    Date: Saturday 11th November 2017

    Time: 0800 - 0900

    Venue: Seminar Lounge, Level 8 (Non-Cancer) & Auditorium, Level 1 & G (Cancer)

    The Young Investigator Award (YIA) gives recognition to young investigators below the age of 35 on 31st December 2017, who is working on outstanding and original research in the field of molecular medicine and cancer. A total of 2 awards will be given (1 each for cancer and non-cancer). Judging will be based on originality of the research, the impact and relevance of research findings, all to be delivered in an oral presentation on 11th November 2017.

    CATEGORY 1

    Non Cancer

    Chairperson: Dr. Nor Adzimah Johdi (UKM, Malaysia)

    Venue: Seminar Lounge, Level 8

    YIA-NC1

    “Digenic Inheritance of Heterozygous FANCA and BRCA2 Mutations in a VACTERL-H Patient”

    by Zam Zureena Mohd Rani (UKM Medical Molecular Biology Institute, UKM)

    YIA-NC2

    “Protein network analysis on the association of PCOS and other diseases towards unraveling its molecular mechanism”

    by Nor Afiqah Aleng (Institute of Systems Biology, UKM)

    YIA-NC3 “Genotype-Phenotype Correlations in Patients with Osteogenesis Imperfecta”

    by Nadiah Mohd Nawawi (UKM Medical Molecular Biology Institute, UKM)

    YIA-NC4 “Detection of Helicobacter pylori in Gastric Biopsy by Urease Test, Culture and PCR”

    by Noor Masyitah Jumahat (MARA University of Technology)

    YIA-NC5

    “Mutations in KIF27, GNAS and IFT140 Genes are Associated with VACTERL Association”

    by Siti Aishah Sulaiman (UKM Medical Molecular Biology Institute, UKM)

    YIA-NC6 “Gut Microbiota Diversity in Malaysians: A Pilot Study”

    by Muhammad Afiq Osman (UKM Medical Molecular Biology Institute, UKM)

    12

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    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    CATEGORY 2

    Cancer

    Chairperson: Dr. Chin Siok Fong (UKM, Malaysia)

    Venue: Auditorium, Level G & 1

    YIA-CA1

    “Elucidation of Signal Transduction Pathways Involved in Molecular Subtypes of Endometrial Cancer”

    by Nurul Syakima Ab Mutalib (UKM Medical Molecular Biology Institute, UKM)

    YIA-CA2

    “Novel Genomic Aberrations Detected with Customised DNA Microarray in Acute Myeloid Leukaemia (AML) Patients That Could Related to Patient’s Survival Status”

    by Angeli Ambayya (Hospital Ampang)

    YIA-CA3

    “The Landscape of Somatic Mutations in Malaysian Colorectal Cancer Patients using Whole Genome Sequencing”

    by Ryia Illani Mohd Yunos (UKM Medical Molecular Biology Institute, UKM)

    YIA-CA4

    “Methylation-Specific PCR Assay for Quantification of DNA Methylation of SPG20 Gene in Colorectal Cancer”

    by Maizatul Akma Mamat (International Islamic University Malaysia)

    YIA-CA5 “LOC285629 Regulates Cell Proliferation and Motility in Colorectal Cancer Cells”

    by Siti Nurmi Nasir (UKM Medical Molecular Biology Institute, UKM)

    YIA-CA6 “Epigenome Analysis of Colorectal Cancer: A Genome Wide Approach”

    by Muhiddin Ishak (UKM Medical Molecular Biology Institute, UKM)

    13

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Free Papers Presentations

    Chairperson: Dr. Lee Pey Yee (UKM, Malaysia)

    Venue: Auditorium, Level G & 1

    “Elucidating the Effect of YB-1 Protein on the Stromal Expression of Collagenases in Malignant Melanoma Cells in vitro”

    by Wisam Nabeel Ibrahim (Faculty of Nursing, International Islamic University Malaysia)

    “Biological Properties of Tumour Subpopulations in Nasopharyngeal Carcinoma”

    by Susan Ling Ling Hoe (Institute for Medical Research)

    “Relapsed-Related Genes in Childhood Acute Myeloid Leukemia Revealed by Whole Genome Sequencing of Diagnostic, Remission and Relapsed Samples”

    by Habsah Aziz (UKM Medical Molecular Biology Institute, UKM)

    “Maritoclax Represses Anti-Apoptotic Protein MCL-1 and Sensitizes Nasopharyngeal Carcinoma Cell Lines to BH3-Mimetic ABT-263”

    by Nethia Mohana Kumaran (School of Biological Sciences, USM)

    “Evaluation of the Sequence-Specific Peptide-Binding Activity of AGR2 Has Identified Specific Interaction Sites on the Oncogenic Receptor EpCAM”

    by Mohamad Aimanuddin Bin Mohtar (UKM Medical Molecular Biology Institute, UKM)

    “Pilot toxicology Study of a Novel Sirtuin Inhibitor as a Potential Therapeutic Candidate in Colorectal Cancer”

    by Lee Yuen Ting (Institute for Research in Molecular Medicine, USM)

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    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Lab Visitation & Meet the Expert Sessions LAB VISITATION

    DATE: 10TH OCTOBER 2017 (FRIDAY)TIME: 1.00 P.M TO 2.00 P.M (AFTER LUNCH)

    All participants are cordially invited to visit our labs.

    GROUND FLOOR

    BIOBANK

    The largest Biobank in Southeast Asia with a collection of 6.2 million biospecimen tubes.

    LEVEL 2

    GENOME SEQUENCING LABORATORY

    Visit our state-of-the-art centre for genome sequencing research. Our laboratory is equipped with the latest and fastest sequencing machines, including HiSeq, MiSeq, Ion Proton and Ion PGM Sequencer.

    PROTEOMIC LABORATORY

    Visit our state-of-the-art centre for proteomic research. The 2 main equipment in this lab are ‘ABSciex 5600 + LCMS Triple TOF’ and ‘Bruker UltrafleXtreme MALDI-TOF/TOF’.

    UMBI MUSEUM

    Come and learn about UMBI’s history. The exhibits include a collection of our first batch of lab equipment and the time-line of key events in the journey of UMBI as a research centre.

    LEVEL 3

    C. ELEGANS LABORATORY

    This lab is used for the culture and maintenance of C. elegans. These worms are ideal biological models for a better understanding of the cellular processes because they share many homologous genes with humans.

    UMBI-ANGKASA MICROGRAVITY LAB

    This lab is equipped with the one and only ‘Desktop Random Positioning Machine (RPM) from Dutch Space Technolo-gies’ in Malaysia, which enables the simulation of microgravity involving small model organisms like C. elegans, plants and seeds.

    MEET THE EXPERT SESSIONS

    DATE: 12TH OCTOBER 2017 (SUNDAY)TIME: 7.30 A.M TO 8.30 A.M

    GROUP VENUE LEVEL SPEAKER

    1 UMBI Meeting Room 9

    Please refer to the secretariat for more information2 The Malaysian Cohort Project Meeting Room 7

    3 Seminar Room 5

    If interested, please register your name at the notice board located at UMBI main lobby

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  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Conference Information

    Conference Venue and SecretariatUKM Medical Molecular Biology Institute (UMBI)

    UKM Medical Centre (UKMMC)Jalan Yaacob Latiff, Bandar Tun Razak

    56000 Cheras, Kuala Lumpur, MALAYSIAPhone: 603-91718459 / 8461

    Fax: 603-91717185Email: [email protected]

    Website: http://www.ukm.my/umbi/rcmm

    LanguageThe official language of the conference is English.

    Certificate of AttendanceA certificate of attendance will be issued to all registered delegates.

    ParkingFree and Paid parking lots and spaces are provided near the conference venue. Please ask the secretariat and information counter for more information.

    WIFI and Internet AccessFree WIFI or internet access is available for all participants upon registration. Please ask the secretariat and information counter for more information.

    Instructions to PresentersPlease see details in http://www.ukm.my/umbi/rcmm for more information. For all the sessions, the rooms are equipped with a computer, Wi-Fi, a projector and a screen. Presenters are requested to bring their own USB device so that they can upload their presentations onto the computer. To save time, this procedure should be done during the break preceding the session.

    Poster ExhibitionThe poster exhibition will be held on according to their respective sessions. Please refer to schedule on the website at http://www.ukm.my/umbi/rcmm, as well as the full list of the selected abstracts.

    Trade ExhibitionA trade exhibition will be held at the lobby of the conference venue. Please refer to the layout and directory of the exhibitors on page 18.

    InsuranceThe Secretariat cannot accept liability for personal injuries and / or loss or damage to property belonging to meeting participants, either during or as a result of the meeting.

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  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Emergency Evacuation PlanEMERGENCY EVACUATION MAP (AUDITORIUM UMBI, LEVEL G)

    üDO NOT USE THE LIFT IN CASE OF EMERGENCY.üPLEASE EXIT VIA THE NEAREST STAIRCASE.

    üTHE GATHERING POINT IS LOCATED AT THE CARPARK NEXT TO UMBI’S BUILDING.

    Emergency Contact No.Reception Desk: 03-9145 9239

    Floor Manager: 019-2799913 (Raziff)

    Emergency Evacuation Map (Level 1)

    DO NOT USE THE LIFT IN CASE OF EMERGENCY, PLEASE EXIT VIA THE NEAREST STAIRCASE.THE GATHERING POINT IS LOCATED AT THE CARPARK NEXT TO UMBI’S BUILDING.

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  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Layout and Directory of The Exhibitors

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  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Organising Committee

    AdvisorProfessor Tan Sri Dato’ Seri Dr. Noor Azlan Ghazali

    Vice-ChancellorUniversiti Kebangsaan Malaysia

    ChairmanProfessor Datuk Dr. A Rahman A Jamal

    Organising Chairman &Director

    UKM Medical Molecular Biology Institute (UMBI)Universiti Kebangsaan Malaysia

    Deputy ChairmanProfessor Dr. Shamsul Azhar Shah

    Deputy Director (Academic and International Affairs)UKM Medical Molecular Biology Institute (UMBI)

    Universiti Kebangsaan Malaysia

    Scientific CommitteeProfessor Datuk Dr. A Rahman A Jamal, UKM

    Professor Dr. Shamsul Azhar Shah, UKMAssociate Professor Dr. Neoh Hui-Min, UKM

    Dr. Nor Azian Abdul Murad, UKMDr. Chin Siok Fong, UKM

    Dr. Nor Adzimah Johdi, UKMDr. Nurul Syakima Ab Mutalib, UKM

    Dr. Nadiah Abu, UKM

    Registration & SouvenirsNorsuzana Abdul Rahman

    Nadzirah SelamatZuraini Abdul Razak

    Afifah Awang

    Exhibition & SponsorshipDr. Nurul Syakima Ab Mutalib

    Dr. Nor Azian Abdul MuradDr. Nadiah Abu

    Dr. Chin Siok FongDr. Nor Adzimah JohdiDr. Tan Shing Cheng

    Editorial & PublicationDr. Siti Aishah Sulaiman

    Ang Mia Yang

    Special DutiesMohd Arman KamaruddinMohd Shaharom Abdullah

    Muhamad Hafiz Mohamed AminMohd Ridzuwann Che Halim

    Muhedir Mohamad

    SecretaryFarliza Zakaria

    TreasurerNadzirah Selamat

    Technical & Audio VisualZainal Azmir Ramli

    Raja Fadhil Raja Abdul RahmanHanif Zulkhairi Mohamad Said

    Mohd Ridhwan Abd. RazakMuhammad Nazirul ‘Azim Mohd Arpandi

    Poster & OralAssociate Professor Dr. Neoh Hui-Min

    Professor Dr. Shamsul Azhar ShahAssociate Professor Dr. Tidi Maharani Hassan

    Dr. Lee Pey YeeSiti Nurmi Nasir

    Publicity & SpeakersDr. Ezanee Azlina Mohamad Hanif

    Ilyahanis Sa’ariAng Mia Yang

    Mohd Raziff Alias

    Protocol & ProgrammeMohd Raziff Alias

    Food & BeverageNorshamsiah Hamim

    Nurul Izza UmarNooranizah Amdan

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    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    Acknowledgement

    Professor Tan Sri Dr. Zakri Abdul HamidScience Advisor for the Prime Minister of Malaysia

    Professor Tan Sri Dato’ Seri Dr. Noor Azlan GhazaliVice-Chancellor, Universiti Kebangsaan Malaysia (UKM)

    Ministry of Health (MOH), MalaysiaMinistry of Higher Education (MOHE), Malaysia

    Universiti Kebangsaan Malaysia (UKM)Universiti Malaya (UM), MalaysiaUniversiti Sains Malaysia (USM)Universiti Putra Malaysia (UPM)

    Institute for Medical Research (IMR), MalaysiaCancer Research Malaysia, Malaysia

    Hospital Ampang, MalaysiaUniversity of Newcastle, Australia

    A* Star, SingaporeNational University of Singapore (NUS), SingaporeGenome Institute of Singapore (GIS), Singapore

    Chulalongkorn University, ThailandLee Kong Chian School of Medicine, Nanyang Technological University, Singapore

    First BASE Laboratories Sdn BhdSengenics Sdn BhdFC-Bios Sdn Bhd

    QIAGEN Biotechnology (M) Sdn BhdNext Gene Scientific Sdn BhdKinematic Resources Sdn Bhd

    Analisa Resources (M) Sdn BhdNano Life Quest Sdn Bhd

    Biospensa ResourcesResearch Instruments Sdn Bhd

    Science Vision Sdn BhdAgilent Technologies

    Biomarketing Services (M) Sdn BhdGenomax Technologies Sdn Bhd

    Prima Nexus Sdn BhdFisher Scientific (M) Sdn Bhd

    Neoscience Sdn BhdSynergy Scientific Sdn Bhd

    Medigene Sdn BhdInterscience Sdn Bhd

    Sciencewerke Sdn BhdBio-Diagnostics Sdn BhdBita Lifescience Sdn Bhd

    Tree Code Sdn Bhd

    And to Everyone Involved.

    20

  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

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    # Our Sponsors #

    21

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    # Our Sponsors #

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    # Our Sponsors #

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  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

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    # Our Sponsors #

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    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

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    # Our Sponsors #

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  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

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    # Our Sponsors #

    26

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    # Our Sponsors #

    27

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    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

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    # Our Sponsors #

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    # Our Sponsors #

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    # Our Sponsors #

    Scan Me

    Tree Code Sdn Bhd (Registration No: 1005134-W)

    52-1, Jalan Ramin 2/KS7, Bandar Botanic, 41200 Klang, Malaysia Tel : +603-3319 0414

    E-mail: [email protected]

    Design-Services-Distribution By

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  • 7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FORCANCER RESEARCH (NCRR) MALAYSIAIN CONJUNCTION WITH 3CANCER RESEARCH (NCRR) MALAYSIA

    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    NOTES

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    7TH REGIONAL CONFERENCE ON MOLECULAR MEDICINE (RCMM)IN CONJUNCTION WITH 3RD NATIONAL CONFERENCE FOR

    CANCER RESEARCH (NCRR) MALAYSIA

    NOTES

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