congenital gingival granular cell tumor
TRANSCRIPT
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NAME : ALI TAHIR BAJWACLASS : 3rd YEAR BDSRoll No: 1804
CONGENITAL GINGIVAL GRANULAR CELL TUMOR
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OUTLINE INTRODUCTION
CLINICAL FEATURES
HISTOPATHOLOGY
TREATMENT
SUMMARY
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CONGENITAL GINGIVAL GRANULAR CELL TUMOR
A pedunculated growth on the anterior maxilla or mandible of newborns that is composed of granular cells.
The congenital gingival granular cell tumor is also known as:1. Congenital epulis of the newborn2. Congenital granular cell epulis
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An infant with a pedunculated, multilobular lesion of the anterior alveolar ridge.Tissue of origin is still controversial.
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CLINICAL FEATURES1. Lesions are found only in newborn2. Lesions mostly occur in anterior maxilla and
occasionally lesions are found in the anterior mandible
3. Occurrence : Females > Males4. Lesions are pedunculated, originating from
crest of alveolar ridge5. Texture: Smooth surface6. Size: several cm in diameter(1-9)7. Colour: Pink
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Hematoxylin and Eosin (H and E) stained section show uniform pattern of granular cells with outer surface of atrophic stratified squamous epithelium
HISTOPATHOLOGY
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• Large, rounded cells
• Granular cytoplasm• Rounded nuclei
High-power microscopy show
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• Lesion is composed of sheets of large cells with a granular cytoplasm and vascular, noncollagenous stroma.
• Lesions contain autophagic vacuoles• Lesions are negative for S-100 protein
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TREATMENT• Surgical Excision that includes the base of stalk• Recurrence is rare
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SUMMARY• Newborns• Composition: Granular cells• Lesion is multilobular &
pedunculated• F>M• Colour: Pink• Smooth surface• Size: 1-9 cm• Treatment: Surgically excised• Reoccurrence: Rare
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