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C O M P L E T E F I L L I N G A N D P A C K A G I N G S O L U T I O N S
MARKET SEGMENTSPharmaceutical aseptic Pharmaceutical non-asepticCosmetic, health, beauty aids,personal care productsFood, beverage, dairyChemical, paint, industrial products
RESPONDING TO THE WORLD’S PLANT MANAGERS, OPERATION MANAGERS AND ENGINEERSFOR NEARLY 100 YEARS
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Cozzoli Machine Company is a global leader in the design, manufacture, distribution, and
service of precision cleaning, sterilizing, filling, and closing systems. Quality craftsman-
ship has always been the cornerstone of our foundation and we are dedicated to continu-
ing that tradition of excellence. The products we engineer today are designed to take you
beyond tomorrow, because at Cozzoli research and development doesn’t end when a
system is successful. We continually update our methods and equipment, integrating fast
moving technologies that shape the products we provide worldwide.
I am committed toinsuring that our products
are designed and manu-factured to the highest
quality standards in the industry and dedicated to providing exceptional and
dependable service.
Joan Cozzoli RooneyPresidentCozzoli Machine Company
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The most responsive team forall your packaging needs…Our expertise lies in the engineering and
manufacturing of exceptional equipment,
custom designed to your specifications for
a multi-faceted turnkey operation. As a
single source provider of individual components
through full lines, our projects are defined by
your individual requirements.
Progressive Engineering…We utilize on-going technologies with design
features that save time in product changeover
and enhance productivity. Some examples are:
• The use of the latest PLC’s makes operation
easier than ever, allowing the operator to
monitor and adjust volume, speed, and
container size.
• Equipment upstream and downstream can
be controlled from the same control panel, ensuring a smooth running, integrated line.
• No-tool changeovers save time when changing product or container size. This capability
reduces set-up time and increases throughput particularly when running a wide variety of
products and containers.
Dependability…The quality machines we build today, just as those built and still operating since the
1900’s, demonstrate the value that Cozzoli Machine Company places on reliability.
Rugged construction and dedicated workmanship you can depend on contribute to an
efficient, smooth-running operation.
Value Added… Cozzoli will meet the specifications and level of automation you require with machinery of the
highest integrity. We’ll test and fine-tune your equipment in our state of the art 100,000 sq. ft.
facility before shipment to ensure the highest level of performance. A smooth start up eliminates
costly delays.
Unparalleled Service…We boast over three generations of experience in the design and manufacture of precision
equipment matched with peerless dedication to technical service. When your line is down you
need fast service. Cozzoli’s highly trained field service technicians travel the world, providing
factory-direct assistance to protect your investment.
Extensive Parts Inventory and Customer Service…Regularly scheduled preventative maintenance minimizes downtime and assures trouble-free
operation. We maintain an impressive inventory of spare parts and are ever ready to assist
you. You are just a phone call or fax away from receiving prompt, courteous
attention from a Cozzoli customer service representative who will immediately
process your request.
From designers and fabricators to engineers and expeditors, sales
agents and representatives, customer service representatives and
service technicians, our dedicated staff will ensure that you receive
the most productive solutions with unsurpassed support.
HOW WE GET YOU UP FASTER...AND RUNNING LONGER
With a combined sixty years of work experience, Mario DellaFortuna and Morris Bekerman are two of the most respectedtechnical experts in the industry. They represent the qualityand loyalty of employees at Cozzoli Machine Company.
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Fill-to-LevelFill-to-level fillers are especially suited for thin and foamy products (such as cleaning solutions). The fill-to-level fillers compensate for variations in container volume while retaining cosmetic fill accuracy. All fill-to-level fillers operate in the same principles as illustrated: gravity, pressure, and vacuum.
Time PressureTime pressure filling is accomplished by controlling the flow of theproduct through the tubing. The product stays in the manifold thatfeeds the tubes. A computer calculates the product flow timeneeded based upon manifold pressure, nozzle size, and target fill volume.
Piston (industrial and aseptic)Piston fillers are ideally suited for filling a diverse range of products. These fillers are ruggedly designed yet precision built for long trouble free operation. Product viscosities may range from 1 to 100,000 centipoises and above.
Peristaltic PumpNothing but the tube touches the fluid, eliminating the risk of thepump contaminating the fluid or the fluid contaminating the pump.The complete closure of the hose, which is squeezed between ashoe and the track, gives the pump its positive displacement action preventing backflow and eliminating the need for checkvalves when the pump is not running.
Diaphragm PumpDiaphragm pump fillers are suited for corrosive chemicals, abrasive materials, and delicate liquids (blood, insulin, andplasma). This completely enclosed system eliminates air bubbleson small fills and features accurate repeat fills.
Rotary Time PressureTime pressure fillers are well suited for filling heavy viscosity
products. The nozzle is open to the product for a specified amount
of time to achieve proper fill volume. Proper fill is dependent on
three critical areas —— time of fill, pressure of product flow, and
filling speed.
Vacuum Powder This totally enclosed system removes the possibility of productcontamination. Fill volume of each piston can be independentlyadjusted during operation. Two to sixteen fill stations are available.Multiple dose fills are made possible by simply setting the micro-processor. Product loss due to dusting is virtually eliminated.
FILLINGMETHODS
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Outstanding Features of Cozzoli’s Heavy Duty Lab EquipmentCompact si ze - Designed for clean rooms or industrial settings and is ideal for labs or smallproduction facilities.
Plug and play - Easy to set up and even easier to use; plug in and connect to a bulk supply container.
Easy to clean and sterilize - All parts which come in contact with the product are fabricated of316L stainless steel. Easy to disassemble for cleaning and sterilizing. Suitable and designedfor autoclaving, steam and/or gas sterilization. No “o” rings or gaskets.
Built to last - Our small production machines are made to last for decades and built to handleany factory setting including those of food, cosmetic, chemical, and paint facilities.
Highest level of performance - Designed for rapid changeover of parts to handle different products and containers on the same unit.
Equipment available: Ampule hand sealer, screw capper, powder filler, liquid filler, washer, air cleaner (not shown), bench model single valve piston filling machine (BMSV), and miniBMSV (not shown)
Ampule hand sealer
Screw capper
Bench model single valve (BMSV) piston filling machine with pedestal option.
Powder filler
Liquid filler
LAB, PILOT, AND SMALLPRODUCTION
Washer
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Washing Stringent regulations require strict compliance. Cozzoli’s versatile air cleaning and washing systemsoffer ease of operation and simple changeover, making compliance both direct and cost effective.
SterilizingCozzoli depyrogenation tunnels feature unidirectional air flow, process temperature progressioncurves, and significantly reduced sterilization times. They provide the repeatable accuracy necessary for successful validation, qualification, and reliable production capacity. Controllable and reproducible process parameters simplify validation.
Other features include safe zone pressure balance, automatic container density control for bettertemperature stability, friction-free container transport, and easy access to the tunnel interior forcleaning and maintenance.
Filling Cozzoli provides continuous motion fillers with speeds up to 600+ containers a minute. Our fillersperform with outstanding accuracies of +/- 0.5% of fill volume or better. Production and cost saving features include compact size and quick and easy changeover. All liquid contact parts are made of 316 stainless steel and medical grade silicone to accommodate sterile requirements.
Check WeighingThe Cozzoli check weigher is the pharmaceutical industries’ state of the art system and uses magnetic force restoration type weighing technology. This technology provides high speed/highprecision performance.
The system consists of a tare weight unit, a gross weight unit, and controls that identify and storein the memory the net weight of each bottle, simultaneously transmitting this information to theprinter. Additionally, the controller will send a signal either to the reject system and/or the filler for fine fill adjustment. The alarm will send a signal either visually (light tower) or audibly (buzzer)any time a gross weight is over or under pre-set limits.
PHARMACEUTICAL PRODUCTION(SPEEDS OF 600+ PER MINUTE)
Stoppering This high-speed stopper placement machine is capable of full or partial insertion of a variety of stoppers into round bottles and uses smooth, continuous motion to complete its function. Elimination of intermittent mechanical motion makes high-speed placement and part handling attainable. These systems have a no tool changeover, make up and back up detection, PLC controls, jog mode, and sanitary “wipe-down” cGMP design.
By adding optional equipment, i.e., make up and back up controls, the machine becomes fully automated, making it usable with filling and capping equipment by means of up and downstream transfers.
Vision Inspecting Vision inspection at speeds of more than 600 containers per minute brings production throughputto a new level with our vision system. You can inspect 100% of your products and ensure thatyour shipments are defect free. Eliminate inspection personnel, fatigue factor, data collecting, and recording.
Crimping The final component to the Cozzoli filling and stoppering systems is the continuous motion rotarycrimper. Uniquely designed, it is capable of speeds of 600 + per minute and has the ability totest and record the seal pressure of every closure. Automatic vial height adjustment is provided foreasy operator changeover and also is a safeguard against adjustment errors.
Trayloading Utilizing the latest technology in robotic automation, the Cozzoli tray loader is designed for placingvials into either three or four-sided trays for lyophilization. Featuring a contemporary design with a stainless steel exterior, it is low, compact, and built to maximize laminar airflow effectivenesswhere class 100 conditions must be met. Vials can be loaded in straight, staggered, or “N minus1” patterns easily selected from the electronic control and display panel.
Barr ier Isolation TechnologyBarrier isolation technology offers cost savings over traditional cleanroom technology, and providesbetter sterility assurance, contamination control, and safety.
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Filling Whether you need volumetric, fill-to-level, or time/pressure (versa fill) filling, Cozzoli has the rightmachine to meet your requirements. Our rotary and in-line fillers handle an array of products of diverse viscosities (1-100,000 centipoises) and different size containers measuring from fractionalounce to five-gallon units. We incorporate the latest technologies into our designs on a constantbasis ensuring time savings in product changeover and enhanced productivity. Flush-in-place capa-bility is available for our rotary piston and fill-to-level fillers. This allows liquid contact parts to re-main intact on the machine during the flushing process.
Our rotary fill-to-level series accommodates a diverse range of low and high viscosity products usingvacuum, gravity, pressure, or a combination of these filling methods.
Rotary piston fillers are fully automatic machines that accommodate a wide range of containers andproducts of most viscosities at high production speeds of 600+ per minute.
High-speed time/pressure fillers are especially well suited for filling heavy products such as peanutbutter, relish, lotion, shampoo, industrial grease, and glue.
All rotary fillers can be combined for filling and capping in a monoblock design providing you with acompact, space-saving, and cost-efficient combination that is easy to operate, change over, andmaintain.
Capping In-lineThe Versa Cap is a straight through friction disc capper designed to handle a wide variety of capshapes and sizes with minimal changeover time required. The Versa Cap can be built in combinationwith any hi-speed rotary fillers in a monoblock design providing compact, cost-efficient operation.The Versa Cap accommodates threaded caps, snap-on caps and over-caps as well as plugs.
RotaryTorque controlled for precision capping of a wide range of container shapes and sizes, the multi-caprotary capper can be built in combination with any hi-speed rotary fillers in a monoblock design, providing a compact cost-efficient operation. Rotary fillers can accommodate threaded caps, snap-oncaps and over-caps as well as plugs. This extremely versatile and effective machine is designed tohandle caps up to 70mm in diameter at a speed of more than 600 containers per minute.
Monoblock
Versa capper Rotary piston filler
Fill to level filler
Time pressure filler
Rotary fill to level
INDUSTRIALPRODUCTION
C O Z Z O L I M A C H I N E C O M P A N Y T E L ( 7 3 2 ) 5 6 4 - 0 4 0 0 F A X ( 7 3 2 ) 5 6 4 - 0 4 4 4 W W W . C O Z Z O L I . C O M 8
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COZZOLI UNPARALLELED, INTEGRATED LINES:ACCURATE. DURABLE. FAST. DEPENDABLE.
ASEPTIC FILLING LINE • 600+ per minute• Full check weighing• Vision inspecting• High accuracy
INDUSTRIAL FILLING LINE• 900+ per minute• Fill any viscosity• Filling methods for any industry• High accuracy
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BOWL SPEED
MACHINE COMPANYR
MANUALJOG AUTO
START
EMERGENCYSTOP
MAIN SPEED
STOP
START STOP
EMERGENCYSTOP
BOWLVIBRATORYCONVEYOR
SPEED
MAINSPEED
R
MACHINE COMPANY
STARTJUGSTOP
EMERGENCY
WASHER STERILIZERTRAY LOADER UNSCRAMBLER
UNSCRAMBLERCHECK WEIGHER AND FILLER STOPPERING
CRIMPER ACCUMULATOR
GLASSWAREWASHING/STERILIZING
FILLING STERILIZING INACTIVATIONAC CHECKING CODING
CAPPING EXTERNAL WASHING
DECARTON
HEATER BANK
MACHINE COMPANY
R 1000
STOP
START
F5F4F2 F3F1
F9F7 F8F6
INDEX
6040SPEED
F10
8020
2 3
5 6
0
1
4
STOPEMERGENCY
ALLEN BRADLEY PANELVIEW 600
8 97
VACUUM
PURGING
DOSING
STOPEMERGENCY
START
MACHINE COMPANY
R
STOPCONVEYOR
SPEEDVIBRATORY
BOWL
SPEEDMAIN
6.25
[158
.75m
m]
WASHER STERILIZER UNSCRAMBLER POWDER FILLER STOPPERING CRIMPER ACCUMULATOR
SAMPLE FLOOR PLANSFOR INTEGRATED LINES
ASEPTIC FILLING LINE • Washing/sterilizing• Filling• Sterilizing• Capping• Checking/coding
ASEPTIC FILLING LINE • Washer• Tunnel• Unscrambling/accumulating• Powder filler• Stoppering• Crimping
1 0
TRAY LOADER
EMERGENCYSTARTSTOP
4
3
56
7
SPEED
1
0
2
9
8
10
STOP
STERILIZER WASHER UNSCRAMBLER FILLER & STOPPERING
CRIMPER ACCUMULATOR
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ASEPTIC FILLING LINE • Washer• Sterilizer• Unscrambler• Filling and Stoppering• Crimping• Accumulator• Tray loader
INDUSTRIAL FILLING LINE
LABELER
UNSCRAMBLER
FILLER CAPPER
ACCUMULATOR
Just as wine depends upon the perfect proportion of acidity and sweetness,fruit and oak, and alcohol and flavor to create a well-balanced taste, U.S. Dis-tilled Products Co. (USDP) is placing more emphasis on a balance betweenshort and long product runs, and own-brand versus co-packed products tosustain its thriving business. Establishing a bottling facility in 1981 for itsown alcohol product lines, the Princeton, MN-based company later uncorkedits capabilities for other brands. Today, with a recent brand acquisition, USDPhas come full circle. “We’re trying to focus on a balance between our ownbrands and our relationships with other companies, so that we can keep ourplant’s capacity at a very high level,” says Todd Geisness, general managerand executive VP of USDP. Traditionally USDP’s strongpoint had been in producing small runs of 100 to 200 cases of bottled liquor. Thus, it equippedits six filling lines with versatile machinery that allowed for quick changeovers.But, as its brands grew in popularity, so did its run lengths. This evolution,coupled with the competitive nature of the bottling market drove USDP to install a completely new line, outfitted to accommodate larger-volume runsquickly and efficiently.
Today, USDP typically runs three lines per 10-hr day, four days per week,maximizing the efficiencies of both its low- and high-speed equipment tomeet various filling needs. To take advantage of the new line’s speed, USDP
minimizes changeover on the filler by limiting to three the number of bottlesizes run: .750 mL, 1 L and 1.75 L. "We could do all of the sizes if wewanted to,” explains Rowland, “but w e feel that it’s not efficient to fill thesmaller bottles, because the volume is just not there.” Due to the clean-runningoperation of the line’s new MRM/Elgin-supplied filler, products of all viscositiesare run, from water-thin spirits to thick and sugary cordials. But the largestvolumes, notes Rowland, are in the spirits.
The heart of the ne w line is 51-nozzle MRM/Elgin Husky 5 RFL rotary fill-to-level liquid filler that allows for gravity, pressure, or combination gravity/pressure filling. This versatility was vital to USDP’s equipment selection, giventhe company’s large range of product viscosities, and container sizes and materials. “To change over from one mode to another is fairly simple and canbe done in about ten minutes,” says on top of the machine. Notes MRM/Elgin,“The inherent difficulty of filling liquids like cordials is the sugar content. Whendrive parts are below the fill level, the sugar can get into the mechanismwhere it’s hard on cams, bearings and other machine parts.”
Rowland adds that he was also impressed by the filler’s ease of maintenance,made possible by a centralized lubrication system, and the quick changeoverenabled by tool-less changeparts. Changing over from one product to another,while retaining the same bottle size, is a 20-minute process, he notes, while afull changeover can be accomplished in an hour and fifteen minutes. “If youlook at the amount of nozzles we have, that’s pretty quick,” he says. On average, the filler runs at a 230- to 250-bottle/min rate, for a total of 15,000to 20,000 cases/day.
According to USDP’s Geisness, after just more than a year and a half in operation, the new line is virtually bug-free and is delivering “greatly increasedproductivity.” Installing the ne w line to increase our production capability enhanced our flexibility, and this has allowed us to become more efficient.And, obviously, the more efficient you are, the more competitive you can bewhen bidding on a contract. There is no doubt that our ability to be competitivehas resulted in a lot more inquiries from potential customers.”
Reprinted and condensed from PACKAGING DIGEST® October 2002. Copyright © Reed Business Information, a division of Reed Elsevier, Inc.
ARTICLES AND TESTIMONIALS
A redesigned sixth bottling line at spirits manufacturer and co-packer U.S. Distilled
Products provides a 60-percent increase in speed over existing lines.
By Anne Marie Mohan, Senior Editor
SPIRITS SOAR WITH NEW LIQUOR FILLING/LABELING LINE
When Jack Schrum needed a
machine for high volume glass
ampule sealing, he didn’t consider
any other company. He knew that
Cozzoli had the capability to do
what he wanted. When asked about
his experience with Cozzoli’s
Customer Service, he answered,
“Service has been excellent – we
think the world of Sam Alexander,
(Technical Service manager at
Cozzoli.) Since we are located
nearby, Sam can stop in
anytime – one of those 30-year
employees that does whatever we
need. Service and products are
what keep us coming to Cozzoli.”
—from an interview with Jack Schrum of Rutgers University
and member of ISBER
COZZOLI CUSTOMER SERVICE
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Biomune Company is a leading U.S. manufacturer of vaccines for the animalhealth industry. With headquarters in Lenexa, KS, the company producesmore than 50 US Dept. of Agriculture-licensed products and serves customersin 37 countries. Its manufacturing sites utilize state-of-the-art equipment andstandard operating procedures in the production of live and killed vaccines.
In June 2005, Biomune installed an integrated packaging line consisting of a Model UT 36 rotary unscrambler, a Model VR2S-10 in-line monoblocfiller/stopperer and a BT 15 dual automatic tray loader, all from Cozzoli Machine Co. (www.cozzoli.com), to run small vials ranging in size from 5 to 20 cc. The line is installed in a Class 100 clean-room. "Cozzoli wasn't highest or lowest on our list when we started thinking about this project,"says director of manufacturing Bill Krehbiel. "We looked at several other machines, but we have three other Cozzoli machines in our plant, and wehave had good experiences with them, so we decided to stick with Cozzoli."
Glass vials, which have been sterilized by hot air, are delivered to the line ontrays, from which a worker manually pushes them onto the rotary unscramblertable. The unscrambler delivers the vials single-file to a conveyor that trans-ports them to the monobloc filler/stopperer. A slight plastic protrusion on theside of the conveyor near the monobloc unit causes any vials that have fallenover to drop off the edge of the conveyor into a bin.
At the entrance to the intermittent-motion monobloc unit, the vials enter afeedscrew mounted beside the conveyor. The screw extends through the fillingzone of the unit and spaces and controls the vials for filling. The filler runs 10vials at a time, and the feedscrew stops during the filling operation, holdingthe vials while the filling takes place. The nozzles descend, creating a bottom-up fill. The nozzles rise in conjunction as the product is being dispensed, soas not to create any splashing or foaming. The feedscrew starts up again todischarge the filled vials and deliver the next group of vials beneath the nozzles. Each nozzle is served by a dedicated positive-displacement pistonpump that includes a suck-back feature to eliminate dripping. Both fill volumeand the amount of suck back can be adjusted manually to optimize the fill accuracy, which is typically in the 0.5-percent range.
Reprinted and condensed from PACKAGING DIGEST® March 2006. Copyright © Reed Business Information, a division of Reed Elsevier, Inc.
The feedscrew ends at the discharge of the filler, and the vials enter a starwheel that conveys them beneath the stoppering wheel. Stoppers are delivered from an overhead hopper down a track to the wheel. The rotatingstoppering wheel picks up the stoppers, rotates in synchronization with thestarwheel and pushes the stoppers into the vials. The unit can insertlypholization stoppers, which have a slot in the center and are pushed onlypart way into the vials and regular stoppers, which are pushed all the wayinto the vials. The filler/stopperer incorporates an upstream sensor to ensurethere are enough vials on the conveyor entering the unit and a downstreamsensor to detect unstoppered vials. The unit is controlled by a programmable-logic controller that stores the recipes for all of the products run on the line.Vials leaving the stopperer continue on the conveyor, which makes a right-angle turn and delivers them to the Model BT15 dual-tray loader. An infeedsystem directs containers onto the tray loader, where rows of vials arepushed onto three-sided trays. This unit also incorporates an A-B PLC, which counts the number of vials pushed onto a tray and diverts the vials to the adjacent tray when the first tray is filled. A worker then replaces the filled tray with an empty tray, and the process is repeated. "The Cozzoli equipment is of high quality and built to last, and it is relatively simple to set up and operate, since most adjustments do not require tools," says Krehbiel. "Cozzoli also has an excellent service department, so if we do need service, they take care of us immediately."
SMALL-VIAL FILLINGFINESSE
By Jack Mans, Plant Operations Editor
In response to the question of
why they selected Cozzoli to
manufacture vial washers for them,
Steve Panneta of Alk Abello replied,
“We usually choose manufacturers
based on experience and reputation.
We’ve been doing business with
Cozzoli for 25 years, and have had
excellent success with them from the
beginning. Cozzoli advances their
styles and we’ve advanced along
with them. We buy a particular piece
of equipment; a vial washer made
to order. We haven’t had to research
competitors in a very long time;
we’ve stuck with Cozzoli because of
their exceptional products. We are
a repeat customer – third machine
over the years – and we are
extremely happy.”
—from an interview with Steve Panneta of Alk Abello and member of ISPE
1 3
1895 Elgin ManufacturingCompany is startedand develops first
industrial filler
1926 CMC receives first patent
and is awarded first prize at the Belgium
International Exposition
1943 CMC provides fillers to
vaccinate US troops
1974 CMC is named DrugPackager of the Year
1999 CMC becomes first US
based packaging machinerycompany in our marketsegment to achieve ISO
9001 certification
A HISTORY OF INNOVATIONAND PERSONAL ATTENTION
1919 Cozzoli Machine Company(CMC) is founded.
1930CMC designs first monoblock
1953CMC develops first line
1983CMC purchases MRM/ElginCorp. expanding the company’sbusiness into the food, cosmetic,and industrial markets
2003 CMC opens new100,000 sq. ft. facilityin Somerset, NJ
2008President Frank J. Cozzoli poses
with the outstanding Cozzolistaff outside of the Somerset,
New Jersey headquarters.
1 4
1922 CMC develops firstaseptic filler
SYSTEM CERTIFICATION
ISO
9001:2000
Cozzoli Machine Company
50 Schoolhouse Road
Somerset, NJ 08873-1289
Telephone: (732) 564-0400
Fax: (732) 564-0444
www.cozzoli.com
FOR MORE INFORMATION PLEASE CONTACT:
• Application Analysis- Application Engineering- Product Testing
• Product Design- Line/machine design
• Manufacturing
• Line Integration
• Validation- Qualification- Verification
• Installation
• Parts & Service- Genuine Factory Replacement Parts- Maintenance- Field Service- Service Contacts
COZZOLI AT A GLANCE
SYSTEM CERTIFICATION
ISO
9001:2000